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Cheap flights from Knoxville to Sao Paulo from $447

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Sao Paulo departing on 4/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Multiple Airlines Logo
7:30 am - 8:40 pm
TYS
-
GRU
36h 10m
1 stop
Multiple Airlines Logo
1:00 am - 3:30 pm
GRU
-
TYS
15h 30m
2 stops
$1,099Multiple Airlines
Thu, Jul 2 - Mon, Jul 6
LATAM Airlines Logo
7:20 pm - 7:30 pm
TYS
-
GRU
23h 10m
2 stops
LATAM Airlines Logo
10:50 pm - 3:07 pm
GRU
-
TYS
17h 17m
1 stop
$1,226LATAM Airlines
Fri, Sep 4 - Fri, Sep 11
LATAM Airlines Logo
10:05 am - 5:20 am
TYS
-
GRU
18h 15m
2 stops
LATAM Airlines Logo
10:15 am - 11:47 pm
GRU
-
TYS
14h 32m
2 stops
$1,227LATAM Airlines
Fri, Sep 4 - Fri, Sep 11
United Airlines Logo
12:05 pm - 6:30 am
TYS
-
GRU
17h 25m
1 stop
United Airlines Logo
9:30 pm - 10:36 am
GRU
-
TYS
14h 06m
1 stop
$1,243United Airlines
Fri, Sep 4 - Fri, Sep 11
United Airlines Logo
8:20 am - 6:30 am
TYS
-
GRU
21h 10m
2 stops
United Airlines Logo
9:30 pm - 5:12 pm
GRU
-
TYS
20h 42m
2 stops
$1,267United Airlines
Thu, Jul 2 - Tue, Jul 7
American Airlines Logo
7:35 pm - 8:20 am
TYS
-
GRU
11h 45m
1 stop
American Airlines Logo
11:15 pm - 11:59 pm
GRU
-
TYS
25h 44m
1 stop
$1,274American Airlines
Thu, Jul 2 - Tue, Jul 7
American Airlines Logo
6:30 am - 5:55 am
TYS
-
GRU
22h 25m
1 stop
American Airlines Logo
10:00 pm - 1:02 pm
GRU
-
TYS
16h 02m
1 stop
$1,318American Airlines
Fri, May 1 - Sat, May 30
American Airlines Logo
3:58 pm - 8:20 am
TYS
-
GRU
15h 22m
2 stops
American Airlines Logo
10:00 pm - 1:02 pm
GRU
-
TYS
16h 02m
1 stop
$1,322American Airlines
Fri, May 1 - Sat, May 30
LATAM Airlines Logo
4:38 pm - 5:40 am
TYS
-
GRU
12h 02m
1 stop
LATAM Airlines Logo
10:50 pm - 11:09 am
GRU
-
TYS
13h 19m
1 stop
$1,359LATAM Airlines
Fri, May 1 - Sat, May 30
LATAM Airlines Logo
4:38 pm - 5:40 am
TYS
-
GRU
12h 02m
1 stop
LATAM Airlines Logo
10:50 pm - 11:09 am
GRU
-
TYS
13h 19m
1 stop
$1,361LATAM Airlines
Fri, May 1 - Sat, May 30

LATAM Airlines flights from Knoxville to Sao Paulo Guarulhos Intl Airport

Our best LATAM Airlines deals on Knoxville to Sao Paulo Guarulhos Intl Airport flight tickets
LATAM Airlines
Sep 4
TYS7:20 pmKnoxville McGhee Tyson
23h 10m
2 stops
GRU7:30 pmSao Paulo Guarulhos Intl
Sep 11
GRU10:50 pmSao Paulo Guarulhos Intl
17h 17m
1 stop
TYS3:07 pmKnoxville McGhee Tyson
$1,226
LATAM Airlines
Sep 4
TYS10:05 amKnoxville McGhee Tyson
18h 15m
2 stops
GRU5:20 amSao Paulo Guarulhos Intl
Sep 11
GRU10:15 amSao Paulo Guarulhos Intl
14h 32m
2 stops
TYS11:47 pmKnoxville McGhee Tyson
$1,227
LATAM Airlines
May 1
TYS4:38 pmKnoxville McGhee Tyson
12h 02m
1 stop
GRU5:40 amSao Paulo Guarulhos Intl
May 30
GRU10:50 pmSao Paulo Guarulhos Intl
13h 19m
1 stop
TYS11:09 amKnoxville McGhee Tyson
$1,359

United Airlines flights from Knoxville to Sao Paulo Guarulhos Intl Airport

Our best United Airlines deals on Knoxville to Sao Paulo Guarulhos Intl Airport flight tickets
United Airlines
Sep 4
TYS12:05 pmKnoxville McGhee Tyson
17h 25m
1 stop
GRU6:30 amSao Paulo Guarulhos Intl
Sep 11
GRU9:30 pmSao Paulo Guarulhos Intl
14h 06m
1 stop
TYS10:36 amKnoxville McGhee Tyson
$1,243
United Airlines
Jul 2
TYS8:20 amKnoxville McGhee Tyson
21h 10m
2 stops
GRU6:30 amSao Paulo Guarulhos Intl
Jul 7
GRU9:30 pmSao Paulo Guarulhos Intl
20h 42m
2 stops
TYS5:12 pmKnoxville McGhee Tyson
$1,267
United Airlines
Apr 24
TYS11:25 amKnoxville McGhee Tyson
18h 20m
1 stop
GRU6:45 amSao Paulo Guarulhos Intl
May 1
GRU9:30 pmSao Paulo Guarulhos Intl
18h 04m
1 stop
TYS2:34 pmKnoxville McGhee Tyson
$1,501

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Sao Paulo Guarulhos Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 28, 2026.
Use the filters below to find and compare flights from Knoxville to Sao Paulo Guarulhos Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 7/2

7:30 am-8:40 pm

1 stop36h 10m

Sao Paulo Guarulhos Intl

Mon 7/6

1:00 am-3:30 pm

2 stops15h 30m

$1,099

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 9/4

7:20 pm-7:30 pm

2 stops23h 10m

Sao Paulo Guarulhos Intl

Fri 9/11

10:50 pm-3:07 pm

1 stop17h 17m

$1,226

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 9/4

10:05 am-5:20 am

2 stops18h 15m

Sao Paulo Guarulhos Intl

Fri 9/11

10:15 am-11:47 pm

2 stops14h 32m

$1,227

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 9/4

12:05 pm-6:30 am

1 stop17h 25m

Sao Paulo Guarulhos Intl

Fri 9/11

9:30 pm-10:36 am

1 stop14h 06m

$1,243

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 7/2

8:20 am-6:30 am

2 stops21h 10m

Sao Paulo Guarulhos Intl

Tue 7/7

9:30 pm-5:12 pm

2 stops20h 42m

$1,267

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 7/2

7:35 pm-8:20 am

1 stop11h 45m

Sao Paulo Guarulhos Intl

Tue 7/7

11:15 pm-11:59 pm

1 stop25h 44m

$1,274

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 5/1

6:30 am-5:55 am

1 stop22h 25m

Sao Paulo Guarulhos Intl

Sat 5/30

10:00 pm-1:02 pm

1 stop16h 02m

$1,318

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 5/1

3:58 pm-8:20 am

2 stops15h 22m

Sao Paulo Guarulhos Intl

Sat 5/30

10:00 pm-1:02 pm

1 stop16h 02m

$1,322
Quickest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 5/1

4:38 pm-5:40 am

1 stop12h 02m

Sao Paulo Guarulhos Intl

Sat 5/30

10:50 pm-11:09 am

1 stop13h 19m

$1,359

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 5/1

4:38 pm-5:40 am

1 stop12h 02m

Sao Paulo Guarulhos Intl

Sat 5/30

10:50 pm-11:09 am

1 stop13h 19m

$1,361

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Knoxville to Sao Paulo Guarulhos Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Knoxville to Sao Paulo Guarulhos Intl Airport flights?

You could potentially save up to 39% on your flight if you consider stops on a Knoxville to Sao Paulo Guarulhos Intl Airport flight.

When to book flights from Knoxville to Sao Paulo Guarulhos Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Sao Paulo Guarulhos Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Sao Paulo Guarulhos Intl Airport (TYS to GRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Sao Paulo Guarulhos Intl Airport

Fastest flight time

13h 11m

Direct flights

None
The fastest flight from Knoxville to Sao Paulo Guarulhos Intl Airport takes 13h 11m
There are no direct flights from Knoxville to Sao Paulo Guarulhos Intl Airport. There are no popular flight routes from Knoxville to Sao Paulo Guarulhos Intl Airport.
Search flight deals

  • How far is Knoxville McGhee Tyson to Sao Paulo Guarulhos Intl by plane?

    Sao Paulo Guarulhos Intl is 4773.7 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 13h 11m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo Guarulhos Intl Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo Guarulhos Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Sao Paulo Guarulhos Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Sao Paulo Guarulhos Intl Airport.

  • What documentation or ID do you need to fly to Sao Paulo Guarulhos Intl Airport?

    The travel and health documents required for your trip to Sao Paulo Guarulhos Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Sao Paulo Guarulhos Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Santos
Guarulhos
Campinas
Guarujá
Aparecida

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Sao Paulo?

It is quick and easy to find Knoxville to Sao Paulo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Sao Paulo that suits you.

Can I find flights from Knoxville to Sao Paulo with flexible booking policies on momondo?

All flight searches from Knoxville to Sao Paulo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Sao Paulo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Sao Paulo from Knoxville.

I’m not ready to book a flight from Knoxville to Sao Paulo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Sao Paulo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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