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Cheap flights from Knoxville to Sao Paulo from $305

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Sao Paulo departing on 6/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Knoxville to Sao Paulo

Cheap round-trip flights

Enter your travel dates to find the best prices.
GOL Logo
6:00 am - 11:05 pm
TYS
-
GRU
16h 05m
2 stops
GOL Logo
9:55 pm - 7:18 pm
GRU
-
TYS
22h 23m
2 stops
$1,020GOL
Fri, Jul 10 - Fri, Jul 24
LATAM Airlines Logo
2:30 pm - 9:35 am
TYS
-
GRU
17h 05m
1 stop
LATAM Airlines Logo
9:30 pm - 9:12 am
GRU
-
TYS
13h 42m
1 stop
$1,053LATAM Airlines
Thu, Nov 12 - Mon, Nov 16
LATAM Airlines Logo
3:55 pm - 8:55 am
TYS
-
GRU
15h 00m
2 stops
LATAM Airlines Logo
10:15 am - 11:46 pm
GRU
-
TYS
15h 31m
2 stops
$1,057LATAM Airlines
Thu, Nov 12 - Mon, Nov 16
LATAM Airlines Logo
2:30 pm - 8:55 am
TYS
-
GRU
16h 25m
2 stops
LATAM Airlines Logo
11:45 pm - 5:18 pm
GRU
-
TYS
19h 33m
1 stop
$1,058LATAM Airlines
Thu, Nov 12 - Mon, Nov 16
GOL Logo
6:00 am - 10:45 pm
TYS
-
GRU
15h 45m
2 stops
GOL Logo
6:00 am - 11:59 pm
GRU
-
TYS
18h 59m
2 stops
$1,117GOL
Sat, Jul 18 - Tue, Jul 28
United Airlines Logo
1:35 pm - 9:30 am
TYS
-
GRU
18h 55m
1 stop
United Airlines Logo
9:50 pm - 11:17 am
GRU
-
TYS
14h 27m
1 stop
$1,147United Airlines
Wed, Sep 23 - Mon, Sep 28
LATAM Airlines Logo
5:37 pm - 8:00 pm
TYS
-
GRU
25h 23m
2 stops
LATAM Airlines Logo
7:30 am - 11:52 pm
GRU
-
TYS
17h 22m
2 stops
$1,188LATAM Airlines
Sat, Jul 18 - Tue, Jul 28
United Airlines Logo
3:25 pm - 6:30 am
TYS
-
GRU
14h 05m
1 stop
United Airlines Logo
9:50 pm - 11:19 am
GRU
-
TYS
14h 29m
1 stop
$1,203United Airlines
Mon, Jun 1 - Mon, Jun 15
LATAM Airlines Logo
10:26 am - 5:30 am
TYS
-
GRU
18h 04m
2 stops
LATAM Airlines Logo
11:40 am - 11:05 am
GRU
-
TYS
24h 25m
2 stops
$1,241LATAM Airlines
Sat, Jul 18 - Tue, Jul 28
United Airlines Logo
7:15 am - 6:30 am
TYS
-
GRU
22h 15m
1 stop
United Airlines Logo
9:30 pm - 10:34 pm
GRU
-
TYS
26h 04m
2 stops
$1,249United Airlines
Fri, Jul 10 - Fri, Jul 24

GOL flights from Knoxville to Sao Paulo Guarulhos Intl Airport

Our best GOL deals on Knoxville to Sao Paulo Guarulhos Intl Airport flight tickets
GOL
Jul 10
TYS6:00 amKnoxville McGhee Tyson
16h 05m
2 stops
GRU11:05 pmSao Paulo Guarulhos Intl
Jul 24
GRU9:55 pmSao Paulo Guarulhos Intl
22h 23m
2 stops
TYS7:18 pmKnoxville McGhee Tyson
$1,020
GOL
Jul 18
TYS6:00 amKnoxville McGhee Tyson
15h 45m
2 stops
GRU10:45 pmSao Paulo Guarulhos Intl
Jul 28
GRU6:00 amSao Paulo Guarulhos Intl
18h 59m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
$1,117
GOL
Jun 5
TYS1:00 pmKnoxville McGhee Tyson
15h 55m
2 stops
GRU5:55 amSao Paulo Guarulhos Intl
Jun 20
GRU9:25 pmSao Paulo Guarulhos Intl
16h 18m
2 stops
TYS12:43 pmKnoxville McGhee Tyson
$4,764

United Airlines flights from Knoxville to Sao Paulo Guarulhos Intl Airport

Our best United Airlines deals on Knoxville to Sao Paulo Guarulhos Intl Airport flight tickets
United Airlines
Sep 23
TYS1:35 pmKnoxville McGhee Tyson
18h 55m
1 stop
GRU9:30 amSao Paulo Guarulhos Intl
Sep 28
GRU9:50 pmSao Paulo Guarulhos Intl
14h 27m
1 stop
TYS11:17 amKnoxville McGhee Tyson
$1,147
United Airlines
Jun 1
TYS3:25 pmKnoxville McGhee Tyson
14h 05m
1 stop
GRU6:30 amSao Paulo Guarulhos Intl
Jun 15
GRU9:50 pmSao Paulo Guarulhos Intl
14h 29m
1 stop
TYS11:19 amKnoxville McGhee Tyson
$1,203
United Airlines
Jul 10
TYS7:15 amKnoxville McGhee Tyson
22h 15m
1 stop
GRU6:30 amSao Paulo Guarulhos Intl
Jul 24
GRU9:30 pmSao Paulo Guarulhos Intl
26h 04m
2 stops
TYS10:34 pmKnoxville McGhee Tyson
$1,249

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Sao Paulo Guarulhos Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 20, 2026.
Use the filters below to find and compare flights from Knoxville to Sao Paulo Guarulhos Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 7/10

6:00 am-11:05 pm

2 stops16h 05m

Sao Paulo Guarulhos Intl

Fri 7/24

9:55 pm-7:18 pm

2 stops22h 23m

$1,020

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 11/12

2:30 pm-9:35 am

1 stop17h 05m

Sao Paulo Guarulhos Intl

Mon 11/16

9:30 pm-9:12 am

1 stop13h 42m

$1,053

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 11/12

3:55 pm-8:55 am

2 stops15h 00m

Sao Paulo Guarulhos Intl

Mon 11/16

10:15 am-11:46 pm

2 stops15h 31m

$1,057

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 11/12

2:30 pm-8:55 am

2 stops16h 25m

Sao Paulo Guarulhos Intl

Mon 11/16

11:45 pm-5:18 pm

1 stop19h 33m

$1,058

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sat 7/18

6:00 am-10:45 pm

2 stops15h 45m

Sao Paulo Guarulhos Intl

Tue 7/28

6:00 am-11:59 pm

2 stops18h 59m

$1,117

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Wed 9/23

1:35 pm-9:30 am

1 stop18h 55m

Sao Paulo Guarulhos Intl

Mon 9/28

9:50 pm-11:17 am

1 stop14h 27m

$1,147

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sat 7/18

5:37 pm-8:00 pm

2 stops25h 23m

Sao Paulo Guarulhos Intl

Tue 7/28

7:30 am-11:52 pm

2 stops17h 22m

$1,188
Quickest round-trip

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Mon 6/1

3:25 pm-6:30 am

1 stop14h 05m

Sao Paulo Guarulhos Intl

Mon 6/15

9:50 pm-11:19 am

1 stop14h 29m

$1,203

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sat 7/18

10:26 am-5:30 am

2 stops18h 04m

Sao Paulo Guarulhos Intl

Tue 7/28

11:40 am-11:05 am

2 stops24h 25m

$1,241

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Fri 7/10

7:15 am-6:30 am

1 stop22h 15m

Sao Paulo Guarulhos Intl

Fri 7/24

9:30 pm-10:34 pm

2 stops26h 04m

$1,249

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Knoxville to Sao Paulo Guarulhos Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Knoxville to Sao Paulo Guarulhos Intl Airport flights?

You could potentially save up to 39% on your flight if you consider stops on a Knoxville to Sao Paulo Guarulhos Intl Airport flight.

When to book flights from Knoxville to Sao Paulo Guarulhos Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Sao Paulo Guarulhos Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Sao Paulo Guarulhos Intl Airport (TYS to GRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Sao Paulo Guarulhos Intl Airport

Fastest flight time

15h 45m

Direct flights

None
The fastest flight from Knoxville to Sao Paulo Guarulhos Intl Airport takes 15h 45m
There are no direct flights from Knoxville to Sao Paulo Guarulhos Intl Airport. There are no popular flight routes from Knoxville to Sao Paulo Guarulhos Intl Airport.
Search flight deals

Frequently asked questions about flying from Knoxville to Sao Paulo Guarulhos Intl Airport

  • How far is Knoxville McGhee Tyson to Sao Paulo Guarulhos Intl by plane?

    Sao Paulo Guarulhos Intl is 4773.7 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 15h 45m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo Guarulhos Intl Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo Guarulhos Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Sao Paulo Guarulhos Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Sao Paulo Guarulhos Intl Airport.

  • What documentation or ID do you need to fly to Sao Paulo Guarulhos Intl Airport?

    The travel and health documents required for your trip to Sao Paulo Guarulhos Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Sao Paulo Guarulhos Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Guarulhos
Santos
Campinas
Guarujá
Aparecida

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Sao Paulo?

It is quick and easy to find Knoxville to Sao Paulo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Sao Paulo that suits you.

Can I find flights from Knoxville to Sao Paulo with flexible booking policies on momondo?

All flight searches from Knoxville to Sao Paulo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Sao Paulo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Sao Paulo from Knoxville.

I’m not ready to book a flight from Knoxville to Sao Paulo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Sao Paulo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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