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Cheap flights from Knoxville to Sao Paulo from $649

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Sao Paulo departing on 4/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:30 am - 8:55 pm
TYS
-
GRU
36h 25m
1 stop
Multiple Airlines Logo
11:10 am - 12:51 pm
GRU
-
TYS
26h 41m
2 stops
$832Multiple Airlines
Sun, Mar 1 - Tue, Mar 17
Multiple Airlines Logo
6:30 am - 8:55 pm
TYS
-
GRU
36h 25m
1 stop
Multiple Airlines Logo
11:10 am - 5:22 pm
GRU
-
TYS
31h 12m
2 stops
$839Multiple Airlines
Sun, Mar 1 - Wed, Mar 18
Multiple Airlines Logo
6:30 am - 8:55 pm
TYS
-
GRU
36h 25m
1 stop
Multiple Airlines Logo
5:25 am - 8:08 am
GRU
-
TYS
27h 43m
2 stops
$840Multiple Airlines
Sun, Mar 1 - Thu, Mar 19
Multiple Airlines Logo
6:30 am - 8:55 pm
TYS
-
GRU
36h 25m
1 stop
Multiple Airlines Logo
4:10 am - 10:59 am
GRU
-
TYS
31h 49m
2 stops
$857Multiple Airlines
Sun, Mar 1 - Sun, Mar 15
Multiple Airlines Logo
6:30 am - 8:55 pm
TYS
-
GRU
36h 25m
1 stop
Multiple Airlines Logo
3:10 am - 6:42 pm
GRU
-
TYS
16h 32m
2 stops
$871Multiple Airlines
Sun, Mar 1 - Fri, Mar 13
Multiple Airlines Logo
6:30 am - 8:55 pm
TYS
-
GRU
36h 25m
1 stop
Multiple Airlines Logo
11:10 am - 12:51 pm
GRU
-
TYS
26h 41m
2 stops
$872Multiple Airlines
Thu, Feb 26 - Tue, Mar 17
Multiple Airlines Logo
2:06 pm - 3:50 am
TYS
-
GRU
35h 44m
2 stops
Multiple Airlines Logo
10:10 am - 6:27 pm
GRU
-
TYS
33h 17m
1 stop
$876Multiple Airlines
Mon, Mar 2 - Thu, Mar 19
Multiple Airlines Logo
6:30 am - 8:55 pm
TYS
-
GRU
36h 25m
1 stop
Multiple Airlines Logo
11:10 am - 5:22 pm
GRU
-
TYS
31h 12m
2 stops
$879Multiple Airlines
Thu, Feb 26 - Wed, Mar 18
Multiple Airlines Logo
6:30 am - 8:55 pm
TYS
-
GRU
36h 25m
1 stop
Multiple Airlines Logo
5:25 am - 8:08 am
GRU
-
TYS
27h 43m
2 stops
$880Multiple Airlines
Thu, Feb 26 - Thu, Mar 19
Multiple Airlines Logo
6:30 am - 8:55 pm
TYS
-
GRU
36h 25m
1 stop
Multiple Airlines Logo
4:10 am - 10:59 am
GRU
-
TYS
31h 49m
2 stops
$897Multiple Airlines
Thu, Feb 26 - Sun, Mar 15

LATAM Airlines flights from Knoxville to Sao Paulo Guarulhos Intl Airport

Our best LATAM Airlines deals on Knoxville to Sao Paulo Guarulhos Intl Airport flight tickets
LATAM Airlines
Mar 1
TYS6:41 pmKnoxville McGhee Tyson
32h 59m
1 stop
GRU5:40 amSao Paulo Guarulhos Intl
Apr 1
GRU10:50 pmSao Paulo Guarulhos Intl
19h 55m
1 stop
TYS5:45 pmKnoxville McGhee Tyson
$1,340
LATAM Airlines
Feb 25
TYS7:02 amKnoxville McGhee Tyson
20h 38m
1 stop
GRU5:40 amSao Paulo Guarulhos Intl
Mar 18
GRU4:30 pmSao Paulo Guarulhos Intl
19h 47m
2 stops
TYS11:17 amKnoxville McGhee Tyson
$1,433
LATAM Airlines
Feb 27
TYS4:03 pmKnoxville McGhee Tyson
22h 27m
2 stops
GRU4:30 pmSao Paulo Guarulhos Intl
Mar 17
GRU3:00 pmSao Paulo Guarulhos Intl
21h 17m
3 stops
TYS11:17 amKnoxville McGhee Tyson
$1,482

United Airlines flights from Knoxville to Sao Paulo Guarulhos Intl Airport

Our best United Airlines deals on Knoxville to Sao Paulo Guarulhos Intl Airport flight tickets
United Airlines
Mar 25
TYS7:25 pmKnoxville McGhee Tyson
13h 55m
1 stop
GRU10:20 amSao Paulo Guarulhos Intl
Apr 10
GRU10:20 pmSao Paulo Guarulhos Intl
25h 09m
1 stop
TYS10:29 pmKnoxville McGhee Tyson
$1,186
United Airlines
Mar 1
TYS5:27 pmKnoxville McGhee Tyson
35h 48m
1 stop
GRU7:15 amSao Paulo Guarulhos Intl
Apr 1
GRU10:20 pmSao Paulo Guarulhos Intl
19h 32m
1 stop
TYS4:52 pmKnoxville McGhee Tyson
$1,300
United Airlines
Mar 1
TYS5:27 pmKnoxville McGhee Tyson
35h 48m
1 stop
GRU7:15 amSao Paulo Guarulhos Intl
Apr 1
GRU9:50 pmSao Paulo Guarulhos Intl
25h 39m
2 stops
TYS10:29 pmKnoxville McGhee Tyson
$1,305

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Sao Paulo Guarulhos Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from Knoxville to Sao Paulo Guarulhos Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 3/1

6:30 am-8:55 pm

1 stop36h 25m

Sao Paulo Guarulhos Intl

Tue 3/17

11:10 am-12:51 pm

2 stops26h 41m

$832

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 3/1

6:30 am-8:55 pm

1 stop36h 25m

Sao Paulo Guarulhos Intl

Wed 3/18

11:10 am-5:22 pm

2 stops31h 12m

$839

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 3/1

6:30 am-8:55 pm

1 stop36h 25m

Sao Paulo Guarulhos Intl

Thu 3/19

5:25 am-8:08 am

2 stops27h 43m

$840

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 3/1

6:30 am-8:55 pm

1 stop36h 25m

Sao Paulo Guarulhos Intl

Sun 3/15

4:10 am-10:59 am

2 stops31h 49m

$857

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Sun 3/1

6:30 am-8:55 pm

1 stop36h 25m

Sao Paulo Guarulhos Intl

Fri 3/13

3:10 am-6:42 pm

2 stops16h 32m

$871

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 2/26

6:30 am-8:55 pm

1 stop36h 25m

Sao Paulo Guarulhos Intl

Tue 3/17

11:10 am-12:51 pm

2 stops26h 41m

$872

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Mon 3/2

2:06 pm-3:50 am

2 stops35h 44m

Sao Paulo Guarulhos Intl

Thu 3/19

10:10 am-6:27 pm

1 stop33h 17m

$876

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 2/26

6:30 am-8:55 pm

1 stop36h 25m

Sao Paulo Guarulhos Intl

Wed 3/18

11:10 am-5:22 pm

2 stops31h 12m

$879

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 2/26

6:30 am-8:55 pm

1 stop36h 25m

Sao Paulo Guarulhos Intl

Thu 3/19

5:25 am-8:08 am

2 stops27h 43m

$880

KnoxvilleSao Paulo

TYS - GRU

TYSGRU

Knoxville McGhee Tyson

Thu 2/26

6:30 am-8:55 pm

1 stop36h 25m

Sao Paulo Guarulhos Intl

Sun 3/15

4:10 am-10:59 am

2 stops31h 49m

$897

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Sao Paulo Guarulhos Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Knoxville to Sao Paulo Guarulhos Intl Airport flights?

You could potentially save up to 26% on your flight if you consider stops on a Knoxville to Sao Paulo Guarulhos Intl Airport flight.

When to book flights from Knoxville to Sao Paulo Guarulhos Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Sao Paulo Guarulhos Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Sao Paulo Guarulhos Intl Airport (TYS to GRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Sao Paulo Guarulhos Intl Airport

Fastest flight time

14h 35m

Direct flights

None
The fastest flight from Knoxville to Sao Paulo Guarulhos Intl Airport takes 14h 35m
There are no direct flights from Knoxville to Sao Paulo Guarulhos Intl Airport. There are no popular flight routes from Knoxville to Sao Paulo Guarulhos Intl Airport.
Search flight deals

  • How far is Knoxville McGhee Tyson to Sao Paulo Guarulhos Intl by plane?

    Sao Paulo Guarulhos Intl is 4773.7 mi away from Knoxville McGhee Tyson. In terms of flight time, this usually takes a little over 14h 35m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo Guarulhos Intl Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Sao Paulo Guarulhos Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Sao Paulo Guarulhos Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Knoxville McGhee Tyson Airport to Sao Paulo Guarulhos Intl Airport.

  • What documentation or ID do you need to fly to Sao Paulo Guarulhos Intl Airport?

    The travel and health documents required for your trip to Sao Paulo Guarulhos Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Sao Paulo Guarulhos Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Guarulhos
Santos
Guarujá
Campinas
Aparecida

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Sao Paulo?

It is quick and easy to find Knoxville to Sao Paulo flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Sao Paulo that suits you.

Can I find flights from Knoxville to Sao Paulo with flexible booking policies on momondo?

All flight searches from Knoxville to Sao Paulo on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Sao Paulo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Sao Paulo from Knoxville.

I’m not ready to book a flight from Knoxville to Sao Paulo right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Sao Paulo flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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