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Cheap flights from Knoxville to Manchester from $376

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Manchester departing on 1/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Lufthansa Logo
7:20 pm - 11:20 pmTYS-MAN
23h 00m2 stops
Lufthansa Logo
6:00 am - 7:29 pmMAN-TYS
18h 29m2 stops
$744Lufthansa
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Mon, Dec 1 - Thu, Dec 4
United Airlines Logo
9:40 am - 12:20 pmTYS-MAN
22h 40m2 stops
United Airlines Logo
6:05 am - 5:28 pmMAN-TYS
16h 23m2 stops
$931United Airlines
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Fri, Mar 27 - Tue, Mar 31
Virgin Atlantic Logo
7:20 pm - 10:30 amTYS-MAN
11h 10m1 stop
Virgin Atlantic Logo
8:40 pm - 9:32 pmMAN-TYS
29h 52m2 stops
$936Virgin Atlantic
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Fri, Mar 27 - Tue, Mar 31
Virgin Atlantic Logo
2:30 pm - 7:55 amTYS-MAN
13h 25m2 stops
Virgin Atlantic Logo
11:10 am - 11:00 pmMAN-TYS
16h 50m2 stops
$942Virgin Atlantic
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Fri, Mar 27 - Tue, Mar 31
Delta Logo
4:00 pm - 10:30 amTYS-MAN
14h 30m1 stop
Delta Logo
11:00 am - 11:44 pmMAN-TYS
17h 44m1 stop
$948Delta
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Fri, Mar 27 - Tue, Mar 31
Multiple Airlines Logo
8:07 pm - 4:05 pmTYS-MAN
14h 58m2 stops
Multiple Airlines Logo
1:30 pm - 11:28 pmMAN-TYS
14h 58m1 stop
$979Multiple Airlines
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Mon, Dec 1 - Thu, Dec 4
Delta Logo
8:35 am - 8:20 amTYS-MAN
18h 45m2 stops
Delta Logo
1:30 pm - 10:31 amMAN-TYS
26h 01m1 stop
$1,180Delta
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Mon, Dec 1 - Wed, Dec 31
Multiple Airlines Logo
11:29 am - 7:00 amTYS-MAN
14h 31m1 stop
Multiple Airlines Logo
10:30 am - 9:44 pmMAN-TYS
16h 14m1 stop
$1,216Multiple Airlines
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Mon, Dec 1 - Thu, Dec 4
Air Canada Logo
9:50 am - 10:20 amTYS-MAN
19h 30m3 stops
Air Canada Logo
6:10 am - 10:56 amMAN-TYS
33h 46m3 stops
$2,496Air Canada
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Mon, Dec 1 - Wed, Dec 31
Air Canada Logo
5:45 am - 10:20 amTYS-MAN
23h 35m3 stops
Air Canada Logo
6:10 am - 10:56 amMAN-TYS
33h 46m3 stops
$3,219Air Canada
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Mon, Dec 1 - Wed, Dec 31

United Airlines flights from Knoxville to Manchester

Our best United Airlines deals on Knoxville to Manchester flight tickets
United Airlines
Mar 27
TYS9:40 amKnoxville McGhee Tyson
22h 40m
2 stops
MAN12:20 pmManchester
Mar 31
MAN6:05 amManchester
16h 23m
2 stops
TYS5:28 pmKnoxville McGhee Tyson
$931
Find similar
United Airlines
Dec 1
TYS2:25 pmKnoxville McGhee Tyson
16h 55m
2 stops
MAN12:20 pmManchester
Dec 31
MAN6:00 amManchester
33h 56m
2 stops
TYS10:56 amKnoxville McGhee Tyson
$1,171
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Virgin Atlantic flights from Knoxville to Manchester

Our best Virgin Atlantic deals on Knoxville to Manchester flight tickets
Virgin Atlantic
Mar 27
TYS7:20 pmKnoxville McGhee Tyson
11h 10m
1 stop
MAN10:30 amManchester
Mar 31
MAN8:40 pmManchester
29h 52m
2 stops
TYS9:32 pmKnoxville McGhee Tyson
$936
Find similar
Virgin Atlantic
Mar 27
TYS2:30 pmKnoxville McGhee Tyson
13h 25m
2 stops
MAN7:55 amManchester
Mar 31
MAN11:10 amManchester
16h 50m
2 stops
TYS11:00 pmKnoxville McGhee Tyson
$942
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momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Manchester that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 11, 2025.
Use the filters below to find and compare flights from Knoxville to Manchester that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 12/1

7:20 pm-11:20 pm

2 stops23h 00m

Manchester

Thu 12/4

6:00 am-7:29 pm

2 stops18h 29m

$744

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 3/27

9:40 am-12:20 pm

2 stops22h 40m

Manchester

Tue 3/31

6:05 am-5:28 pm

2 stops16h 23m

$931

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 3/27

7:20 pm-10:30 am

1 stop11h 10m

Manchester

Tue 3/31

8:40 pm-9:32 pm

2 stops29h 52m

$936

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 3/27

2:30 pm-7:55 am

2 stops13h 25m

Manchester

Tue 3/31

11:10 am-11:00 pm

2 stops16h 50m

$942

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Fri 3/27

4:00 pm-10:30 am

1 stop14h 30m

Manchester

Tue 3/31

11:00 am-11:44 pm

1 stop17h 44m

$948

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 12/1

8:07 pm-4:05 pm

2 stops14h 58m

Manchester

Thu 12/4

1:30 pm-11:28 pm

1 stop14h 58m

$979

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 12/1

8:35 am-8:20 am

2 stops18h 45m

Manchester

Wed 12/31

1:30 pm-10:31 am

1 stop26h 01m

$1,180

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 12/1

11:29 am-7:00 am

1 stop14h 31m

Manchester

Thu 12/4

10:30 am-9:44 pm

1 stop16h 14m

$1,216

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 12/1

9:50 am-10:20 am

3 stops19h 30m

Manchester

Wed 12/31

6:10 am-10:56 am

3 stops33h 46m

$2,496

KnoxvilleManchester

TYS - MAN

TYSMAN

Knoxville McGhee Tyson

Mon 12/1

5:45 am-10:20 am

3 stops23h 35m

Manchester

Wed 12/31

6:10 am-10:56 am

3 stops33h 46m

$3,219

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Manchester

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Manchester?

The cheapest day to depart from Knoxville to Manchester is on a Tuesday. Travelers who choose to depart for Manchester on a Tuesday will often find tickets for as low as $877. On the other hand, Monday is the most expensive day to depart from Knoxville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,389.

What is the cheapest time of day to depart on your flight to Manchester?

Flying to Manchester from Knoxville in the evening is the least expensive time of day to depart. momondo users have found prices as low as $823 when looking at flights departing in the evening. Flights to Manchester are more costly in the afternoon, with an average ticket price of $1,196. Departure times in the afternoon fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Knoxville to Manchester

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Manchester according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Manchester (TYS to MAN) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Manchester

Direct flights

None
There are no direct flights from Knoxville to Manchester. There are no popular flight routes from Knoxville to Manchester.
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  • How far is Knoxville McGhee Tyson to Manchester by plane?

    Manchester is 3949.9 mi away from Knoxville McGhee Tyson. Typically, this will take 11h 10m by plane in normal conditions.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Manchester Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Manchester Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Manchester Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Manchester Airport.

  • What documentation or ID do you need to fly to Manchester Airport?

    The required travel and health documents for your Manchester Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Manchester Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Manchester?

Best airlines flying from Knoxville to Manchester

Compare and see reviews for airlines that fly from Knoxville to Manchester with momondo
Airline
Rating
Free Cancellation
Price
Virgin AtlanticPriceFrom $730Free CancellationRating
7.5
673 reviews
Search Virgin Atlantic flights
DeltaPriceFrom $747Free CancellationRating
7.9
8,004 reviews
Search Delta flights
American AirlinesPriceFrom $798Free CancellationRating
7.2
11,046 reviews
Search American Airlines flights

Traveling to a place near Manchester?

Book flights to Manchester if you plan to visit one of these locations
York
Llandudno
Leicester
Conwy
Chester
Windermere
Ambleside
Bradford
Telford
Sheffield
Derby
Stoke-on-Trent
Lincoln
Southport
Rochdale
Bolton
Harrogate
Sale
Warrington
Wrexham

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Manchester?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Knoxville to Manchester for you.

Can I find flights from Knoxville to Manchester with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Knoxville to Manchester flights to just show those with flexible booking policies.

How can momondo help me find flights from Knoxville to Manchester?

Once all potential Knoxville to Manchester flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Manchester right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Manchester flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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