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Cheap flights from Knoxville to Madrid from $362

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Madrid departing on 2/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Madrid

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:01 am - 8:00 am
TYS
-
MAD
19h 59m
1 stop
Delta Logo
9:00 am - 9:06 pm
MAD
-
TYS
17h 06m
2 stops
$483Delta
Thu, Feb 26 - Wed, Mar 11
Delta Logo
5:35 am - 8:00 am
TYS
-
MAD
20h 25m
2 stops
Delta Logo
9:00 am - 8:50 pm
MAD
-
TYS
16h 50m
2 stops
$494Delta
Thu, Feb 26 - Wed, Mar 11
United Airlines Logo
9:40 am - 9:15 am
TYS
-
MAD
18h 35m
2 stops
United Airlines Logo
12:40 pm - 2:50 pm
MAD
-
TYS
31h 10m
2 stops
$524United Airlines
Mon, Mar 9 - Mon, Mar 16
United Airlines Logo
7:00 am - 1:00 pm
TYS
-
MAD
25h 00m
2 stops
United Airlines Logo
12:40 pm - 2:50 pm
MAD
-
TYS
31h 10m
2 stops
$540United Airlines
Sun, Mar 8 - Mon, Mar 16
United Airlines Logo
9:40 am - 11:45 am
TYS
-
MAD
21h 05m
2 stops
United Airlines Logo
6:25 am - 7:29 pm
MAD
-
TYS
18h 04m
2 stops
$553United Airlines
Thu, Mar 19 - Thu, Mar 26
United Airlines Logo
10:55 am - 1:00 pm
TYS
-
MAD
20h 05m
2 stops
United Airlines Logo
6:00 am - 10:49 am
MAD
-
TYS
33h 49m
2 stops
$561United Airlines
Thu, Mar 5 - Thu, Mar 12
Delta Logo
6:01 am - 8:00 am
TYS
-
MAD
19h 59m
1 stop
Delta Logo
10:05 am - 5:45 pm
MAD
-
TYS
12h 40m
1 stop
$590Delta
Thu, Mar 5 - Thu, Mar 12
Delta Logo
6:01 am - 8:00 am
TYS
-
MAD
19h 59m
1 stop
Delta Logo
9:00 am - 11:57 pm
MAD
-
TYS
19h 57m
2 stops
$594Delta
Thu, Mar 5 - Thu, Mar 12
Delta Logo
5:01 pm - 7:00 am
TYS
-
MAD
32h 59m
1 stop
Delta Logo
9:00 am - 8:35 pm
MAD
-
TYS
16h 35m
1 stop
$595Delta
Sun, Mar 8 - Mon, Mar 16
Delta Logo
6:01 am - 8:00 am
TYS
-
MAD
19h 59m
1 stop
Delta Logo
6:00 am - 8:35 pm
MAD
-
TYS
19h 35m
2 stops
$599Delta
Thu, Mar 5 - Fri, Mar 13

British Airways flights from Knoxville to Madrid

Our best British Airways deals on Knoxville to Madrid flight tickets
British Airways
Feb 18
TYS6:10 amKnoxville McGhee Tyson
23h 45m
2 stops
MAD11:55 amMadrid Barajas
Feb 28
MAD1:15 pmMadrid Barajas
13h 52m
1 stop
TYS9:07 pmKnoxville McGhee Tyson
$677
British Airways
Jan 30
TYS7:44 amKnoxville McGhee Tyson
27h 11m
2 stops
MAD4:55 pmMadrid Barajas
Feb 1
MAD8:35 pmMadrid Barajas
30h 21m
2 stops
TYS8:56 pmKnoxville McGhee Tyson
$681
British Airways
Feb 18
TYS6:10 amKnoxville McGhee Tyson
31h 55m
2 stops
MAD8:05 pmMadrid Barajas
Feb 28
MAD12:50 pmMadrid Barajas
39h 05m
2 stops
TYS9:55 pmKnoxville McGhee Tyson
$682

United Airlines flights from Knoxville to Madrid

Our best United Airlines deals on Knoxville to Madrid flight tickets
United Airlines
Mar 9
TYS9:40 amKnoxville McGhee Tyson
18h 35m
2 stops
MAD9:15 amMadrid Barajas
Mar 16
MAD12:40 pmMadrid Barajas
31h 10m
2 stops
TYS2:50 pmKnoxville McGhee Tyson
$524
United Airlines
Mar 8
TYS7:00 amKnoxville McGhee Tyson
25h 00m
2 stops
MAD1:00 pmMadrid Barajas
Mar 16
MAD12:40 pmMadrid Barajas
31h 10m
2 stops
TYS2:50 pmKnoxville McGhee Tyson
$540
United Airlines
Mar 19
TYS9:40 amKnoxville McGhee Tyson
21h 05m
2 stops
MAD11:45 amMadrid Barajas
Mar 26
MAD6:25 amMadrid Barajas
18h 04m
2 stops
TYS7:29 pmKnoxville McGhee Tyson
$553

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 2/26

6:01 am-8:00 am

1 stop19h 59m

Madrid Barajas

Wed 3/11

9:00 am-9:06 pm

2 stops17h 06m

$483

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 2/26

5:35 am-8:00 am

2 stops20h 25m

Madrid Barajas

Wed 3/11

9:00 am-8:50 pm

2 stops16h 50m

$494

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 3/9

9:40 am-9:15 am

2 stops18h 35m

Madrid Barajas

Mon 3/16

12:40 pm-2:50 pm

2 stops31h 10m

$524

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sun 3/8

7:00 am-1:00 pm

2 stops25h 00m

Madrid Barajas

Mon 3/16

12:40 pm-2:50 pm

2 stops31h 10m

$540

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 3/19

9:40 am-11:45 am

2 stops21h 05m

Madrid Barajas

Thu 3/26

6:25 am-7:29 pm

2 stops18h 04m

$553

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 3/5

10:55 am-1:00 pm

2 stops20h 05m

Madrid Barajas

Thu 3/12

6:00 am-10:49 am

2 stops33h 49m

$561

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 3/5

6:01 am-8:00 am

1 stop19h 59m

Madrid Barajas

Thu 3/12

10:05 am-5:45 pm

1 stop12h 40m

$590

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 3/5

6:01 am-8:00 am

1 stop19h 59m

Madrid Barajas

Thu 3/12

9:00 am-11:57 pm

2 stops19h 57m

$594

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sun 3/8

5:01 pm-7:00 am

1 stop32h 59m

Madrid Barajas

Mon 3/16

9:00 am-8:35 pm

1 stop16h 35m

$595

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 3/5

6:01 am-8:00 am

1 stop19h 59m

Madrid Barajas

Fri 3/13

6:00 am-8:35 pm

2 stops19h 35m

$599

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Knoxville to Madrid flights?

You could potentially save up to 18% on your flight if you consider stops on a Knoxville to Madrid flight.

When to book flights from Knoxville to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Madrid according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Madrid (TYS to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Madrid

Fastest flight time

15h 08m

Direct flights

None
The fastest flight from Knoxville to Madrid takes 15h 08m
There are no direct flights from Knoxville to Madrid. There are no popular flight routes from Knoxville to Madrid.
Search flight deals

  • How far is Knoxville McGhee Tyson to Madrid Barajas by plane?

    The straight-line distance from Knoxville McGhee Tyson to Madrid Barajas is 4209.0 mi. 15h 08m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Madrid Barajas Airport.

  • What documentation or ID do you need to fly to Madrid Barajas Airport?

    The required travel and health documents for your Madrid Barajas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Madrid Barajas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Madrid?

Best airlines flying from Knoxville to Madrid

Compare and see reviews for airlines that fly from Knoxville to Madrid with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $586Free CancellationRating
7.2
11,199 reviews
Search American Airlines flights
British AirwaysPriceFrom $612Free CancellationRating
6.7
7,705 reviews
Search British Airways flights

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Toledo
Segovia
Fuenlabrada
Getafe
Cuenca
San Lorenzo de El Escorial
Guadalajara

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Madrid?

It is quick and easy to find Knoxville to Madrid flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Madrid that suits you.

Can I find flights from Knoxville to Madrid with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Madrid from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Madrid?

Once you have performed a search for Knoxville to Madrid flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to Madrid right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Madrid flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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