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Cheap flights from Knoxville to Madrid from $581

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Madrid departing on 6/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Madrid

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
10:00 am - 8:05 am
TYS
-
MAD
16h 05m
1 stop
United Airlines Logo
1:30 pm - 2:37 pm
MAD
-
TYS
31h 07m
2 stops
$825United Airlines
Wed, Sep 9 - Fri, Sep 25
United Airlines Logo
7:15 am - 8:05 am
TYS
-
MAD
18h 50m
2 stops
United Airlines Logo
1:30 pm - 2:37 pm
MAD
-
TYS
31h 07m
2 stops
$829United Airlines
Wed, Sep 9 - Fri, Sep 25
United Airlines Logo
5:45 am - 8:05 am
TYS
-
MAD
20h 20m
1 stop
United Airlines Logo
11:15 am - 2:37 pm
MAD
-
TYS
33h 22m
1 stop
$845United Airlines
Tue, Sep 8 - Fri, Sep 25
United Airlines Logo
5:45 am - 8:05 am
TYS
-
MAD
20h 20m
1 stop
United Airlines Logo
6:20 am - 10:36 am
MAD
-
TYS
34h 16m
2 stops
$847United Airlines
Tue, Sep 8 - Fri, Sep 25
United Airlines Logo
5:45 am - 8:05 am
TYS
-
MAD
20h 20m
1 stop
United Airlines Logo
12:45 pm - 2:37 pm
MAD
-
TYS
31h 52m
2 stops
$849United Airlines
Tue, Sep 8 - Fri, Sep 25
United Airlines Logo
6:30 am - 8:05 am
TYS
-
MAD
19h 35m
2 stops
United Airlines Logo
6:20 am - 10:36 am
MAD
-
TYS
34h 16m
2 stops
$851United Airlines
Tue, Sep 8 - Fri, Sep 25
United Airlines Logo
5:45 am - 9:00 am
TYS
-
MAD
21h 15m
2 stops
United Airlines Logo
12:45 pm - 2:37 pm
MAD
-
TYS
31h 52m
2 stops
$853United Airlines
Tue, Sep 8 - Fri, Sep 25
United Airlines Logo
1:35 pm - 8:05 am
TYS
-
MAD
12h 30m
1 stop
United Airlines Logo
10:50 am - 9:33 am
MAD
-
TYS
28h 43m
2 stops
$1,115United Airlines
Fri, Jul 24 - Mon, Aug 3
United Airlines Logo
7:19 pm - 8:05 am
TYS
-
MAD
30h 46m
1 stop
United Airlines Logo
10:50 am - 9:33 am
MAD
-
TYS
28h 43m
2 stops
$1,121United Airlines
Fri, Jul 17 - Mon, Jul 27
United Airlines Logo
10:00 am - 11:50 am
TYS
-
MAD
19h 50m
2 stops
United Airlines Logo
10:50 am - 9:33 am
MAD
-
TYS
28h 43m
2 stops
$1,123United Airlines
Fri, Jul 17 - Mon, Jul 27

United Airlines flights from Knoxville to Madrid

Our best United Airlines deals on Knoxville to Madrid flight tickets
United Airlines
Sep 9
TYS10:00 amKnoxville McGhee Tyson
16h 05m
1 stop
MAD8:05 amMadrid Barajas
Sep 25
MAD1:30 pmMadrid Barajas
31h 07m
2 stops
TYS2:37 pmKnoxville McGhee Tyson
$825
United Airlines
Sep 9
TYS7:15 amKnoxville McGhee Tyson
18h 50m
2 stops
MAD8:05 amMadrid Barajas
Sep 25
MAD1:30 pmMadrid Barajas
31h 07m
2 stops
TYS2:37 pmKnoxville McGhee Tyson
$829
United Airlines
Sep 8
TYS5:45 amKnoxville McGhee Tyson
20h 20m
1 stop
MAD8:05 amMadrid Barajas
Sep 25
MAD11:15 amMadrid Barajas
33h 22m
1 stop
TYS2:37 pmKnoxville McGhee Tyson
$845

Lufthansa flights from Knoxville to Madrid

Our best Lufthansa deals on Knoxville to Madrid flight tickets
Lufthansa
Jun 9
TYS7:19 pmKnoxville McGhee Tyson
16h 21m
2 stops
MAD5:40 pmMadrid Barajas
Jun 23
MAD7:00 amMadrid Barajas
22h 54m
2 stops
TYS11:54 pmKnoxville McGhee Tyson
$1,182
Lufthansa
Jun 3
TYS7:19 pmKnoxville McGhee Tyson
16h 21m
2 stops
MAD5:40 pmMadrid Barajas
Aug 4
MAD5:55 amMadrid Barajas
20h 39m
2 stops
TYS8:34 pmKnoxville McGhee Tyson
$1,183
Lufthansa
May 24
TYS10:10 amKnoxville McGhee Tyson
25h 30m
2 stops
MAD5:40 pmMadrid Barajas
May 31
MAD6:25 pmMadrid Barajas
28h 33m
2 stops
TYS4:58 pmKnoxville McGhee Tyson
$1,247

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 9/9

10:00 am-8:05 am

1 stop16h 05m

Madrid Barajas

Fri 9/25

1:30 pm-2:37 pm

2 stops31h 07m

$825

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 9/9

7:15 am-8:05 am

2 stops18h 50m

Madrid Barajas

Fri 9/25

1:30 pm-2:37 pm

2 stops31h 07m

$829

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 9/8

5:45 am-8:05 am

1 stop20h 20m

Madrid Barajas

Fri 9/25

11:15 am-2:37 pm

1 stop33h 22m

$845

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 9/8

5:45 am-8:05 am

1 stop20h 20m

Madrid Barajas

Fri 9/25

6:20 am-10:36 am

2 stops34h 16m

$847

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 9/8

5:45 am-8:05 am

1 stop20h 20m

Madrid Barajas

Fri 9/25

12:45 pm-2:37 pm

2 stops31h 52m

$849

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 9/8

6:30 am-8:05 am

2 stops19h 35m

Madrid Barajas

Fri 9/25

6:20 am-10:36 am

2 stops34h 16m

$851

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 9/8

5:45 am-9:00 am

2 stops21h 15m

Madrid Barajas

Fri 9/25

12:45 pm-2:37 pm

2 stops31h 52m

$853
Quickest round-trip

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 7/24

1:35 pm-8:05 am

1 stop12h 30m

Madrid Barajas

Mon 8/3

10:50 am-9:33 am

2 stops28h 43m

$1,115

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 7/17

7:19 pm-8:05 am

1 stop30h 46m

Madrid Barajas

Mon 7/27

10:50 am-9:33 am

2 stops28h 43m

$1,121

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 7/17

10:00 am-11:50 am

2 stops19h 50m

Madrid Barajas

Mon 7/27

10:50 am-9:33 am

2 stops28h 43m

$1,123

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Madrid?

What is the cheapest month to fly to Madrid?

The month of February is, on average, the cheapest month to fly to Madrid from Knoxville, with most prices found around $0. If you don’t want to visit Madrid in February, then you should wait until January to fly from Knoxville, when ticket prices are also cheap, with an average price of $0.

Can stopping save me money on Knoxville to Madrid flights?

You could potentially save up to 74% on your flight if you consider stops on a Knoxville to Madrid flight.

When to book flights from Knoxville to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Madrid according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Madrid (TYS to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Madrid

Fastest flight time

13h 23m

Direct flights

None
The fastest flight from Knoxville to Madrid takes 13h 23m
There are no direct flights from Knoxville to Madrid. There are no popular flight routes from Knoxville to Madrid.
Search flight deals

Frequently asked questions about flying from Knoxville to Madrid

  • How far is Knoxville McGhee Tyson to Madrid Barajas by plane?

    The straight-line distance from Knoxville McGhee Tyson to Madrid Barajas is 4209.0 mi. 13h 23m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Madrid Barajas Airport.

  • What documentation or ID do you need to fly to Madrid Barajas Airport?

    The required travel and health documents for your Madrid Barajas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Madrid Barajas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Madrid?

Best airlines flying from Knoxville to Madrid

Compare and see reviews for airlines that fly from Knoxville to Madrid with momondo
Airline
Rating
Free Cancellation
Price
British AirwaysPriceFrom $549Free CancellationRating
6.7
7,945 reviews
Search British Airways flights
American AirlinesPriceFrom $586Free CancellationRating
7.1
11,668 reviews
Search American Airlines flights
United AirlinesPriceFrom $587Free CancellationRating
7.4
9,683 reviews
Search United Airlines flights

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Toledo
Segovia
Fuenlabrada
Getafe
Cuenca
San Lorenzo de El Escorial
Guadalajara

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Madrid?

It is quick and easy to find Knoxville to Madrid flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Madrid that suits you.

Can I find flights from Knoxville to Madrid with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Madrid from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Madrid?

Once you have performed a search for Knoxville to Madrid flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to Madrid right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Madrid flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Fly your favorite airline to Madrid

Airlines are sorted and displayed according to clicks in the past 7 days on momondo
American Airlines
British Airways
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