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Cheap flights from Knoxville to Madrid from $408

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Madrid departing on 3/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Madrid

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
2:25 pm - 11:10 am
TYS
-
MAD
14h 45m2 stops
Multiple Airlines Logo
1:35 pm - 2:49 pm
MAD
-
TYS
31h 14m2 stops
$467Multiple Airlines
Mon, Jan 12 - Mon, Jan 19
United Airlines Logo
7:25 pm - 8:00 am
TYS
-
MAD
30h 35m2 stops
United Airlines Logo
12:35 pm - 7:29 pm
MAD
-
TYS
35h 54m2 stops
$472United Airlines
Tue, Feb 17 - Mon, Mar 16
United Airlines Logo
11:07 am - 9:15 am
TYS
-
MAD
16h 08m2 stops
United Airlines Logo
1:35 pm - 7:27 pm
MAD
-
TYS
35h 52m2 stops
$473United Airlines
Fri, Jan 23 - Tue, Jan 27
British Airways Logo
2:19 pm - 11:55 am
TYS
-
MAD
15h 36m2 stops
British Airways Logo
12:40 pm - 10:54 pm
MAD
-
TYS
16h 14m1 stop
$476British Airways
Mon, Jan 12 - Mon, Jan 19
Air Canada Logo
2:21 pm - 12:05 pm
TYS
-
MAD
39h 44m2 stops
Air Canada Logo
12:40 pm - 2:50 pm
MAD
-
TYS
31h 10m2 stops
$477Air Canada
Sat, Feb 14 - Tue, Mar 17
Lufthansa Logo
2:25 pm - 11:10 am
TYS
-
MAD
14h 45m2 stops
Lufthansa Logo
7:25 am - 8:47 pm
MAD
-
TYS
18h 22m2 stops
$478Lufthansa
Thu, Jan 15 - Tue, Mar 17
British Airways Logo
2:19 pm - 4:55 pm
TYS
-
MAD
20h 36m2 stops
British Airways Logo
12:50 pm - 8:56 pm
MAD
-
TYS
38h 06m2 stops
$481British Airways
Wed, Jan 28 - Wed, Feb 4
Finnair Logo
12:20 pm - 9:25 am
TYS
-
MAD
15h 05m1 stop
Finnair Logo
12:55 am - 11:20 pm
MAD
-
TYS
27h 25m1 stop
$483Finnair
Tue, Feb 17 - Mon, Mar 16
British Airways Logo
7:44 am - 8:55 am
TYS
-
MAD
19h 11m1 stop
British Airways Logo
1:15 pm - 8:56 pm
MAD
-
TYS
13h 41m1 stop
$486British Airways
Sat, Jan 10 - Fri, Jan 23
Delta Logo
6:01 am - 8:00 am
TYS
-
MAD
19h 59m1 stop
Delta Logo
9:00 am - 8:30 pm
MAD
-
TYS
16h 30m1 stop
$488Delta
Tue, Feb 17 - Wed, Mar 18

United Airlines flights from Knoxville to Madrid

Our best United Airlines deals on Knoxville to Madrid flight tickets
United Airlines
Feb 17
TYS7:25 pmKnoxville McGhee Tyson
30h 35m
2 stops
MAD8:00 amMadrid Barajas
Mar 16
MAD12:35 pmMadrid Barajas
35h 54m
2 stops
TYS7:29 pmKnoxville McGhee Tyson
$472
Find similar
United Airlines
Jan 23
TYS11:07 amKnoxville McGhee Tyson
16h 08m
2 stops
MAD9:15 amMadrid Barajas
Jan 27
MAD1:35 pmMadrid Barajas
35h 52m
2 stops
TYS7:27 pmKnoxville McGhee Tyson
$473
Find similar
United Airlines
Feb 20
TYS2:21 pmKnoxville McGhee Tyson
15h 24m
2 stops
MAD11:45 amMadrid Barajas
Mar 20
MAD6:25 amMadrid Barajas
19h 22m
2 stops
TYS8:47 pmKnoxville McGhee Tyson
$499
Find similar

British Airways flights from Knoxville to Madrid

Our best British Airways deals on Knoxville to Madrid flight tickets
British Airways
Jan 12
TYS2:19 pmKnoxville McGhee Tyson
15h 36m
2 stops
MAD11:55 amMadrid Barajas
Jan 19
MAD12:40 pmMadrid Barajas
16h 14m
1 stop
TYS10:54 pmKnoxville McGhee Tyson
$476
Find similar
British Airways
Jan 28
TYS2:19 pmKnoxville McGhee Tyson
20h 36m
2 stops
MAD4:55 pmMadrid Barajas
Feb 4
MAD12:50 pmMadrid Barajas
38h 06m
2 stops
TYS8:56 pmKnoxville McGhee Tyson
$481
Find similar
British Airways
Jan 10
TYS7:44 amKnoxville McGhee Tyson
19h 11m
1 stop
MAD8:55 amMadrid Barajas
Jan 23
MAD1:15 pmMadrid Barajas
13h 41m
1 stop
TYS8:56 pmKnoxville McGhee Tyson
$486
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 1/12

2:25 pm-11:10 am

2 stops14h 45m

Madrid Barajas

Mon 1/19

1:35 pm-2:49 pm

2 stops31h 14m

$467

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 2/17

7:25 pm-8:00 am

2 stops30h 35m

Madrid Barajas

Mon 3/16

12:35 pm-7:29 pm

2 stops35h 54m

$472

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Fri 1/23

11:07 am-9:15 am

2 stops16h 08m

Madrid Barajas

Tue 1/27

1:35 pm-7:27 pm

2 stops35h 52m

$473

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 1/12

2:19 pm-11:55 am

2 stops15h 36m

Madrid Barajas

Mon 1/19

12:40 pm-10:54 pm

1 stop16h 14m

$476

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 2/14

2:21 pm-12:05 pm

2 stops39h 44m

Madrid Barajas

Tue 3/17

12:40 pm-2:50 pm

2 stops31h 10m

$477

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 1/15

2:25 pm-11:10 am

2 stops14h 45m

Madrid Barajas

Tue 3/17

7:25 am-8:47 pm

2 stops18h 22m

$478

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 1/28

2:19 pm-4:55 pm

2 stops20h 36m

Madrid Barajas

Wed 2/4

12:50 pm-8:56 pm

2 stops38h 06m

$481

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 2/17

12:20 pm-9:25 am

1 stop15h 05m

Madrid Barajas

Mon 3/16

12:55 am-11:20 pm

1 stop27h 25m

$483

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Sat 1/10

7:44 am-8:55 am

1 stop19h 11m

Madrid Barajas

Fri 1/23

1:15 pm-8:56 pm

1 stop13h 41m

$486

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 2/17

6:01 am-8:00 am

1 stop19h 59m

Madrid Barajas

Wed 3/18

9:00 am-8:30 pm

1 stop16h 30m

$488

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Madrid from

How to get the cheapest flight ticket from Knoxville to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Madrid?

The month of December is, on average, the cheapest month to fly to Madrid from Knoxville, with most prices found around $673. If you don’t want to visit Madrid in December, then you should wait until November to fly from Knoxville, when ticket prices are also cheap, with an average price of $686.

What is the cheapest day to depart on your flight to Madrid?

The cheapest day to depart on your flight to Madrid is on a Monday when prices can be found for as low as $758. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Tuesday as prices are generally higher than usual. According to our data, the average ticket price to Madrid on Tuesday is $1,132.

What is the cheapest time of day to depart on your flight to Madrid?

Flying to Madrid from Knoxville in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $831 when looking at flights departing in the afternoon. Flights to Madrid are more costly in the evening, with an average ticket price of $1,100. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on Knoxville to Madrid flights?

You could potentially save up to 32% on your flight if you consider stops on a Knoxville to Madrid flight.

When to book flights from Knoxville to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Madrid according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Madrid (TYS to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Madrid

Fastest flight time

10h 21m

Direct flights

None
The fastest flight from Knoxville to Madrid takes 10h 21m
There are no direct flights from Knoxville to Madrid. There are no popular flight routes from Knoxville to Madrid.
Search flight deals

  • How far is Knoxville McGhee Tyson to Madrid Barajas by plane?

    The straight-line distance from Knoxville McGhee Tyson to Madrid Barajas is 4209.0 mi. 10h 21m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Madrid Barajas Airport.

  • What documentation or ID do you need to fly to Madrid Barajas Airport?

    The required travel and health documents for your Madrid Barajas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Madrid Barajas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Madrid?

Best airlines flying from Knoxville to Madrid

Compare and see reviews for airlines that fly from Knoxville to Madrid with momondo
Airline
Rating
Free Cancellation
Price
British AirwaysPriceFrom $612Free CancellationRating
6.7
7,575 reviews
Search British Airways flights
American AirlinesPriceFrom $642Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Toledo
Segovia
Getafe
Fuenlabrada
Cuenca
San Lorenzo de El Escorial
Guadalajara

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Madrid?

It is quick and easy to find Knoxville to Madrid flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Madrid that suits you.

Can I find flights from Knoxville to Madrid with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Madrid from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Madrid?

Once you have performed a search for Knoxville to Madrid flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to Madrid right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Madrid flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Madrid trip

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