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Cheap flights from Knoxville to Madrid from $343

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Madrid departing on 12/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Madrid

Cheap round-trip flights

Enter your travel dates to find the best prices.
British Airways Logo
7:38 am - 8:55 am
TYS
-
MAD
19h 17m
1 stop
British Airways Logo
12:40 pm - 11:57 pm
MAD
-
TYS
17h 17m
1 stop
$727British Airways
Wed, Dec 2 - Wed, Dec 9
United Airlines Logo
9:45 am - 8:05 am
TYS
-
MAD
16h 20m
1 stop
United Airlines Logo
11:15 am - 9:45 am
MAD
-
TYS
28h 30m
2 stops
$728United Airlines
Mon, Sep 21 - Tue, Oct 6
Delta Logo
7:25 pm - 12:15 pm
TYS
-
MAD
10h 50m
1 stop
Delta Logo
12:45 pm - 9:09 pm
MAD
-
TYS
14h 24m
1 stop
$728Delta
Mon, Sep 21 - Tue, Oct 6
United Airlines Logo
10:45 am - 8:05 am
TYS
-
MAD
15h 20m
2 stops
United Airlines Logo
11:15 am - 9:45 am
MAD
-
TYS
28h 30m
2 stops
$728United Airlines
Mon, Sep 21 - Tue, Oct 6
Iberia Logo
11:35 am - 8:50 am
TYS
-
MAD
15h 15m
1 stop
Iberia Logo
12:00 pm - 10:40 pm
MAD
-
TYS
16h 40m
1 stop
$730Iberia
Wed, Dec 2 - Wed, Dec 9
KLM Logo
2:40 pm - 9:55 am
TYS
-
MAD
13h 15m
1 stop
KLM Logo
7:00 am - 5:24 pm
MAD
-
TYS
16h 24m
2 stops
$736KLM
Wed, Dec 2 - Wed, Dec 9
Multiple Airlines Logo
6:09 pm - 3:20 pm
TYS
-
MAD
15h 11m
2 stops
Multiple Airlines Logo
7:00 am - 5:24 pm
MAD
-
TYS
16h 24m
2 stops
$740Multiple Airlines
Wed, Dec 2 - Wed, Dec 9
United Airlines Logo
7:35 pm - 7:45 am
TYS
-
MAD
30h 10m
1 stop
United Airlines Logo
1:25 pm - 2:42 pm
MAD
-
TYS
55h 17m
2 stops
$744United Airlines
Mon, Dec 7 - Thu, Dec 10
American Airlines Logo
11:35 am - 8:20 am
TYS
-
MAD
14h 45m
1 stop
American Airlines Logo
12:35 pm - 10:01 pm
MAD
-
TYS
15h 26m
1 stop
$765American Airlines
Tue, Oct 20 - Tue, Nov 3
American Airlines Logo
10:49 am - 8:55 am
TYS
-
MAD
16h 06m
1 stop
American Airlines Logo
1:15 pm - 8:56 pm
MAD
-
TYS
13h 41m
1 stop
$835American Airlines
Thu, Dec 24 - Sat, Jan 9

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American Airlines flights from Knoxville to Madrid

Our best American Airlines deals on Knoxville to Madrid flight tickets
American Airlines
Oct 20
TYS11:35 amKnoxville McGhee Tyson
14h 45m
1 stop
MAD8:20 amMadrid Barajas
Nov 3
MAD12:35 pmMadrid Barajas
15h 26m
1 stop
TYS10:01 pmKnoxville McGhee Tyson
$765
American Airlines
Dec 24
TYS10:49 amKnoxville McGhee Tyson
16h 06m
1 stop
MAD8:55 amMadrid Barajas
Jan 9
MAD1:15 pmMadrid Barajas
13h 41m
1 stop
TYS8:56 pmKnoxville McGhee Tyson
$835

Iberia flights from Knoxville to Madrid

Our best Iberia deals on Knoxville to Madrid flight tickets
Iberia
Dec 2
TYS11:35 amKnoxville McGhee Tyson
15h 15m
1 stop
MAD8:50 amMadrid Barajas
Dec 9
MAD12:00 pmMadrid Barajas
16h 40m
1 stop
TYS10:40 pmKnoxville McGhee Tyson
$730
Iberia
Oct 3
TYS8:15 pmKnoxville McGhee Tyson
30h 05m
1 stop
MAD8:20 amMadrid Barajas
Oct 10
MAD9:00 pmMadrid Barajas
32h 59m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
$802
Iberia
Dec 24
TYS11:35 amKnoxville McGhee Tyson
42h 20m
2 stops
MAD11:55 amMadrid Barajas
Jan 9
MAD12:50 pmMadrid Barajas
41h 09m
2 stops
TYS11:59 pmKnoxville McGhee Tyson
$843

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from Knoxville to Madrid that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 12/2

7:38 am-8:55 am

1 stop19h 17m

Madrid Barajas

Wed 12/9

12:40 pm-11:57 pm

1 stop17h 17m

$727

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 9/21

9:45 am-8:05 am

1 stop16h 20m

Madrid Barajas

Tue 10/6

11:15 am-9:45 am

2 stops28h 30m

$728
Quickest round-trip

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 9/21

7:25 pm-12:15 pm

1 stop10h 50m

Madrid Barajas

Tue 10/6

12:45 pm-9:09 pm

1 stop14h 24m

$728

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 9/21

10:45 am-8:05 am

2 stops15h 20m

Madrid Barajas

Tue 10/6

11:15 am-9:45 am

2 stops28h 30m

$728

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 12/2

11:35 am-8:50 am

1 stop15h 15m

Madrid Barajas

Wed 12/9

12:00 pm-10:40 pm

1 stop16h 40m

$730

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 12/2

2:40 pm-9:55 am

1 stop13h 15m

Madrid Barajas

Wed 12/9

7:00 am-5:24 pm

2 stops16h 24m

$736

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Wed 12/2

6:09 pm-3:20 pm

2 stops15h 11m

Madrid Barajas

Wed 12/9

7:00 am-5:24 pm

2 stops16h 24m

$740

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Mon 12/7

7:35 pm-7:45 am

1 stop30h 10m

Madrid Barajas

Thu 12/10

1:25 pm-2:42 pm

2 stops55h 17m

$744

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Tue 10/20

11:35 am-8:20 am

1 stop14h 45m

Madrid Barajas

Tue 11/3

12:35 pm-10:01 pm

1 stop15h 26m

$765

KnoxvilleMadrid

TYS - MAD

TYSMAD

Knoxville McGhee Tyson

Thu 12/24

10:49 am-8:55 am

1 stop16h 06m

Madrid Barajas

Sat 1/9

1:15 pm-8:56 pm

1 stop13h 41m

$835

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Knoxville to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Madrid?

The month of February is, on average, the cheapest month to fly to Madrid from Knoxville, with most prices found around $0. If you don’t want to visit Madrid in February, then you should wait until January to fly from Knoxville, when ticket prices are also cheap, with an average price of $0.

Can stopping save me money on Knoxville to Madrid flights?

You could potentially save up to 74% on your flight if you consider stops on a Knoxville to Madrid flight.

When to book flights from Knoxville to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Madrid according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Madrid (TYS to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Madrid

Fastest flight time

10h 50m

Direct flights

None
The fastest flight from Knoxville to Madrid takes 10h 50m
There are no direct flights from Knoxville to Madrid. There are no popular flight routes from Knoxville to Madrid.
Search flight deals

Frequently asked questions about flying from Knoxville to Madrid

  • How far is Knoxville McGhee Tyson to Madrid Barajas by plane?

    The straight-line distance from Knoxville McGhee Tyson to Madrid Barajas is 4209.0 mi. 10h 50m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Madrid Barajas Airport.

  • What documentation or ID do you need to fly to Madrid Barajas Airport?

    The required travel and health documents for your Madrid Barajas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Madrid Barajas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Knoxville to Madrid?

Best airlines flying from Knoxville to Madrid

Compare and see reviews for airlines that fly from Knoxville to Madrid with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $666Free CancellationRating
7.1
11,841 reviews
Search American Airlines flights

Traveling to a place near Madrid?

Book flights to Madrid if you plan to visit one of these locations
Toledo
Segovia
Fuenlabrada
Getafe
Cuenca
Guadalajara
San Lorenzo de El Escorial

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Madrid?

It is quick and easy to find Knoxville to Madrid flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Madrid that suits you.

Can I find flights from Knoxville to Madrid with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Madrid from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Madrid?

Once you have performed a search for Knoxville to Madrid flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to Madrid right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Madrid flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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