What airlines fly to Madrid?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Madrid from Knoxville according to our data. American Airlines is the first choice among our users, with 58% of people opting to fly with this airline when traveling to Madrid. Keep in mind that there are 4 different airlines that fly to Madrid on a routine basis, so you have a few additional options to choose from.

Which airport is the most popular layover for flights between Knoxville and Madrid?

Philadelphia (PHL) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest connection time from Knoxville to Madrid?

Philadelphia (PHL) has the shortest average layover time for this route: 3h 56m.

What is the cheapest airline that flies from Knoxville McGhee Tyson to Madrid Barajas?

Aer Lingus is the most popular carrier operating from Knoxville McGhee Tyson to Madrid Barajas

Which layover airport has the shortest travel time from Knoxville to Madrid?

Flights connecting via Philadelphia (PHL) have the shortest average one-way travel time: 14h 09m.

Which layover airport offers the lowest fares from Knoxville to Madrid?

Flights via Philadelphia (PHL) offer the lowest average round-trip price of $989.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport were last updated today.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

As of November 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Madrid Barajas Airport.

What documentation or ID do you need to fly to Madrid Barajas Airport?

The required travel and health documents for your Madrid Barajas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Madrid Barajas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$423 Cheap Flights from Knoxville to Madrid in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Knoxville to Madrid

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6:15 am - 9:30 amTYS Knoxville McGhee Tyson-MAD Madrid Barajas

21h 15m1 stop Newark

1:25 pm - 5:11 pmMAD Madrid Barajas-TYS Knoxville McGhee Tyson

33h 46m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$748United Airlines

Sun, Feb 14 - Wed, Feb 17

9:40 am - 9:30 amTYS Knoxville McGhee Tyson-MAD Madrid Barajas

17h 50m2 stops Washington, D.C. Dulles Intl Newark

1:25 pm - 5:11 pmMAD Madrid Barajas-TYS Knoxville McGhee Tyson

33h 46m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$752United Airlines

Sun, Feb 14 - Wed, Feb 17

6:15 am - 9:30 amTYS Knoxville McGhee Tyson-MAD Madrid Barajas

21h 15m1 stop Newark

11:15 am - 7:51 pmMAD Madrid Barajas-TYS Knoxville McGhee Tyson

14h 36m1 stop Newark

$768United Airlines

Sun, Feb 14 - Wed, Feb 17

2:07 pm - 7:45 amTYS Knoxville McGhee Tyson-MAD Madrid Barajas

11h 38m1 stop Washington, D.C. Dulles Intl

11:15 am - 8:54 pmMAD Madrid Barajas-TYS Knoxville McGhee Tyson

15h 39m1 stop Newark

$769United Airlines

Tue, Dec 8 - Thu, Dec 17

7:35 pm - 7:45 amTYS Knoxville McGhee Tyson-MAD Madrid Barajas

30h 10m1 stop Washington, D.C. Dulles Intl

1:25 pm - 1:20 pmMAD Madrid Barajas-TYS Knoxville McGhee Tyson

53h 55m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$810Multiple Airlines

Sun, Nov 29 - Sun, Dec 6

12:02 pm - 2:15 pmTYS Knoxville McGhee Tyson-MAD Madrid Barajas

20h 13m2 stops Chicago O'Hare Intl London Heathrow

12:40 pm - 7:30 pmMAD Madrid Barajas-TYS Knoxville McGhee Tyson

12h 50m1 stop Charlotte Douglas

$816British Airways

Fri, Feb 5 - Fri, Feb 12

6:14 am - 5:45 amTYS Knoxville McGhee Tyson-MAD Madrid Barajas

17h 31m1 stop Charlotte Douglas

1:15 pm - 8:52 pmMAD Madrid Barajas-TYS Knoxville McGhee Tyson

13h 37m1 stop Philadelphia

$818American Airlines

Fri, Feb 5 - Fri, Feb 12

6:00 am - 5:50 amTYS Knoxville McGhee Tyson-MAD Madrid Barajas

17h 50m1 stop Miami

12:40 pm - 11:59 pmMAD Madrid Barajas-TYS Knoxville McGhee Tyson

17h 19m1 stop Charlotte Douglas

$819American Airlines

Sun, Nov 29 - Sun, Dec 6

7:50 am - 2:15 pmTYS Knoxville McGhee Tyson-MAD Madrid Barajas

24h 25m2 stops Chicago O'Hare Intl London Heathrow

6:10 pm - 12:28 amMAD Madrid Barajas-TYS Knoxville McGhee Tyson

36h 18m2 stops London Heathrow Chicago O'Hare Intl

$833British Airways

Sun, Jan 10 - Sat, Jan 16

7:30 am - 8:55 amTYS Knoxville McGhee Tyson-MAD Madrid Barajas

19h 25m1 stop Philadelphia

6:10 pm - 12:28 amMAD Madrid Barajas-TYS Knoxville McGhee Tyson

36h 18m2 stops London Heathrow Chicago O'Hare Intl

$840British Airways

Sun, Jan 10 - Sat, Jan 16

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Air Canada flights from Knoxville to Madrid

Our best Air Canada deals on Knoxville to Madrid flight tickets

Air Canada

Dec 14

TYS9:45 amKnoxville McGhee Tyson

16h 15m

3 stops

MAD8:00 amMadrid Barajas

Dec 21

MAD8:35 amMadrid Barajas

21h 40m

3 stops

TYS12:15 amKnoxville McGhee Tyson

$1,247

Air Canada

Feb 5

TYS9:45 amKnoxville McGhee Tyson

16h 15m

3 stops

MAD8:00 amMadrid Barajas

Feb 12

MAD7:40 amMadrid Barajas

22h 19m

3 stops

TYS11:59 pmKnoxville McGhee Tyson

$1,366

Air Canada

Dec 8

TYS9:45 amKnoxville McGhee Tyson

16h 15m

3 stops

MAD8:00 amMadrid Barajas

Dec 17

MAD7:40 amMadrid Barajas

22h 35m

3 stops

TYS12:15 amKnoxville McGhee Tyson

$1,373

American Airlines flights from Knoxville to Madrid

Our best American Airlines deals on Knoxville to Madrid flight tickets

American Airlines

Feb 5

TYS6:14 amKnoxville McGhee Tyson

17h 31m

1 stop

MAD5:45 amMadrid Barajas

Feb 12

MAD1:15 pmMadrid Barajas

13h 37m

1 stop

TYS8:52 pmKnoxville McGhee Tyson

$818

American Airlines

Nov 29

TYS6:00 amKnoxville McGhee Tyson

17h 50m

1 stop

MAD5:50 amMadrid Barajas

Dec 6

MAD12:40 pmMadrid Barajas

17h 19m

1 stop

TYS11:59 pmKnoxville McGhee Tyson

$819

American Airlines

Dec 14

TYS7:00 amKnoxville McGhee Tyson

19h 55m

1 stop

MAD8:55 amMadrid Barajas

Dec 21

MAD12:40 pmMadrid Barajas

15h 17m

1 stop

TYS9:57 pmKnoxville McGhee Tyson

$924

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Sun 2/14

6:15 am-9:30 am

1 stop21h 15m

Madrid Barajas

Wed 2/17

1:25 pm-5:11 pm

2 stops33h 46m

$748

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Sun 2/14

9:40 am-9:30 am

2 stops17h 50m

Madrid Barajas

Wed 2/17

1:25 pm-5:11 pm

2 stops33h 46m

$752

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Sun 2/14

6:15 am-9:30 am

1 stop21h 15m

Madrid Barajas

Wed 2/17

11:15 am-7:51 pm

1 stop14h 36m

$768

Quickest round-trip

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Tue 12/8

2:07 pm-7:45 am

1 stop11h 38m

Madrid Barajas

Thu 12/17

11:15 am-8:54 pm

1 stop15h 39m

$769

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Sun 11/29

7:35 pm-7:45 am

1 stop30h 10m

Madrid Barajas

Sun 12/6

1:25 pm-1:20 pm

2 stops53h 55m

$810

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Fri 2/5

12:02 pm-2:15 pm

2 stops20h 13m

Madrid Barajas

Fri 2/12

12:40 pm-7:30 pm

1 stop12h 50m

$816

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Fri 2/5

6:14 am-5:45 am

1 stop17h 31m

Madrid Barajas

Fri 2/12

1:15 pm-8:52 pm

1 stop13h 37m

$818

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Sun 11/29

6:00 am-5:50 am

1 stop17h 50m

Madrid Barajas

Sun 12/6

12:40 pm-11:59 pm

1 stop17h 19m

$819

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Sun 1/10

7:50 am-2:15 pm

2 stops24h 25m

Madrid Barajas

Sat 1/16

6:10 pm-12:28 am

2 stops36h 18m

$833

KnoxvilleMadrid

TYS Knoxville McGhee Tyson - MAD Madrid Barajas

TYSMAD

Knoxville McGhee Tyson

Sun 1/10

7:30 am-8:55 am

1 stop19h 25m

Madrid Barajas

Sat 1/16

6:10 pm-12:28 am

2 stops36h 18m

$840

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Knoxville to Madrid

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Madrid?

The month of February is, on average, the cheapest month to fly to Madrid from Knoxville, with most prices found around $0. If you don’t want to visit Madrid in February, then you should wait until November to fly from Knoxville, when ticket prices are also cheap, with an average price of $677.

Can stopping save me money on Knoxville to Madrid flights?

You could potentially save up to 74% on your flight if you consider stops on a Knoxville to Madrid flight.

When to book flights from Knoxville to Madrid

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Madrid according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Madrid (TYS to MAD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Madrid

Best Price Found	$423
Fastest flight time	11h 38m
Direct flights	None

The best one-way flight to Madrid from Knoxville in the past 72 hours is $423. The best round-trip flight deal from Knoxville to Madrid found on momondo in the last 72 hours is $748.

The fastest flight from Knoxville to Madrid takes 11h 38m

There are no direct flights from Knoxville to Madrid. There are no popular flight routes from Knoxville to Madrid.

Search flight deals

Frequently asked questions about flying from Knoxville to Madrid

How far is Knoxville McGhee Tyson to Madrid Barajas by plane?
The straight-line distance from Knoxville McGhee Tyson to Madrid Barajas is 4209.0 mi. 11h 38m is a normal flight duration for this route.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport were last updated today.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?
As of November 2026, there are 2 operators available to choose from for flights from Knoxville McGhee Tyson Airport to Madrid Barajas Airport.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Madrid Barajas Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Madrid Barajas Airport.
What documentation or ID do you need to fly to Madrid Barajas Airport?
The required travel and health documents for your Madrid Barajas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Madrid Barajas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Knoxville to Madrid?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Knoxville to Madrid is United Airlines (59% of total bookings). The next most popular airline is British Airways (41%).

Best airlines flying from Knoxville to Madrid

Compare and see reviews for airlines that fly from Knoxville to Madrid with momondo

Airline	Rating	Free Cancellation	Price
British Airways	PriceFrom $549	Free Cancellation	Rating 6.7 8,281 reviews		Search British Airways flights
United Airlines	PriceFrom $591	Free Cancellation	Rating 7.3 10,458 reviews		Search United Airlines flights

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Why should I use momondo to find a flight deal from Knoxville to Madrid?

It is quick and easy to find Knoxville to Madrid flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Madrid that suits you.

Can I find flights from Knoxville to Madrid with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Madrid from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Madrid?

Once you have performed a search for Knoxville to Madrid flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Knoxville to Madrid right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Madrid flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Cheap flights from Knoxville to Madrid from $423

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Madrid departing on 12/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Air Canada flights from Knoxville to Madrid

Our best Air Canada deals on Knoxville to Madrid flight tickets

American Airlines flights from Knoxville to Madrid

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How to get the cheapest flight ticket from Knoxville to Madrid

What is the cheapest month to fly to Madrid?

Can stopping save me money on Knoxville to Madrid flights?

What is the cheapest airline that flies from Knoxville McGhee Tyson to Madrid Barajas?

What airlines fly to Madrid?

Which airport is the most popular layover for flights between Knoxville and Madrid?

Which layover airport offers the lowest fares from Knoxville to Madrid?

Which layover airport has the shortest travel time from Knoxville to Madrid?

Which layover airport has the shortest connection time from Knoxville to Madrid?

When to book flights from Knoxville to Madrid

Cheap Knoxville to Madrid (TYS to MAD) flight deals and tips

Best Price Found

Fastest flight time

Direct flights

Frequently asked questions about flying from Knoxville to Madrid

Best airlines flying from Knoxville to Madrid

Compare and see reviews for airlines that fly from Knoxville to Madrid with momondo

Traveling to a place near Madrid?

Why use momondo?

An easier way to manage your Madrid trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

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List of cabin classes available on flights landing in Madrid. Availability may vary depending on flight origin and airline.

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