Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Knoxville to Columbus from $122

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Columbus departing on 3/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Knoxville to Columbus

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:20 pm - 11:40 pm
TYS
-
CMH
4h 20m
1 stop
United Airlines Logo
5:30 am - 10:08 am
CMH
-
TYS
4h 38m
1 stop
$287United Airlines
Tue, Apr 7 - Thu, Apr 9
American Airlines Logo
5:00 am - 11:10 am
TYS
-
CMH
6h 10m
1 stop
American Airlines Logo
8:44 am - 2:22 pm
CMH
-
TYS
5h 38m
1 stop
$291American Airlines
Thu, Apr 2 - Tue, Apr 7
Southwest Logo
7:05 am - 12:30 pm
TYS
-
CMH
5h 25m
1 stop
Southwest Logo
1:15 pm - 8:20 pm
CMH
-
TYS
7h 05m
2 stops
$292Southwest
Tue, Apr 7 - Thu, Apr 9
Southwest Logo
8:15 am - 6:20 pm
TYS
-
CMH
10h 05m
2 stops
Southwest Logo
1:15 pm - 8:20 pm
CMH
-
TYS
7h 05m
2 stops
$297Southwest
Tue, Apr 7 - Thu, Apr 9
Multiple Airlines Logo
2:56 pm - 9:41 am
TYS
-
CMH
18h 45m
1 stop
Multiple Airlines Logo
8:03 pm - 5:30 pm
CMH
-
TYS
21h 27m
2 stops
$299Multiple Airlines
Tue, Apr 7 - Sun, Apr 12
United Airlines Logo
5:53 pm - 11:59 pm
TYS
-
CMH
6h 06m
1 stop
United Airlines Logo
6:04 pm - 10:34 pm
CMH
-
TYS
4h 30m
1 stop
$300United Airlines
Tue, Apr 7 - Sun, Apr 12
United Airlines Logo
7:00 am - 1:12 pm
TYS
-
CMH
6h 12m
1 stop
United Airlines Logo
4:10 pm - 10:34 pm
CMH
-
TYS
6h 24m
1 stop
$304United Airlines
Mon, Apr 13 - Fri, Apr 17
Multiple Airlines Logo
7:30 am - 10:32 pm
TYS
-
CMH
15h 02m
1 stop
Multiple Airlines Logo
9:42 am - 9:57 pm
CMH
-
TYS
12h 15m
1 stop
$307Multiple Airlines
Fri, Apr 24 - Sun, Apr 26
Southwest Logo
6:30 am - 2:55 pm
TYS
-
CMH
8h 25m
2 stops
Southwest Logo
4:15 pm - 8:50 pm
CMH
-
TYS
4h 35m
1 stop
$311Southwest
Thu, Apr 2 - Tue, Apr 7
Southwest Logo
6:30 am - 2:55 pm
TYS
-
CMH
8h 25m
2 stops
Southwest Logo
1:15 pm - 7:40 pm
CMH
-
TYS
6h 25m
2 stops
$316Southwest
Thu, Apr 2 - Tue, Apr 7

American Airlines flights from Knoxville to Columbus Airport

Our best American Airlines deals on Knoxville to Columbus Airport flight tickets
American Airlines
Apr 2
TYS5:00 amKnoxville McGhee Tyson
6h 10m
1 stop
CMH11:10 amColumbus
Apr 7
CMH8:44 amColumbus
5h 38m
1 stop
TYS2:22 pmKnoxville McGhee Tyson
$291
American Airlines
Mar 20
TYS5:02 pmKnoxville McGhee Tyson
4h 17m
1 stop
CMH9:19 pmColumbus
Mar 22
CMH5:02 amColumbus
3h 40m
1 stop
TYS8:42 amKnoxville McGhee Tyson
$417
American Airlines
Mar 23
TYS6:05 amKnoxville McGhee Tyson
5h 33m
1 stop
CMH11:38 amColumbus
Apr 3
CMH3:15 pmColumbus
6h 23m
1 stop
TYS9:38 pmKnoxville McGhee Tyson
$560

Southwest flights from Knoxville to Columbus Airport

Our best Southwest deals on Knoxville to Columbus Airport flight tickets
Southwest
Apr 7
TYS7:05 amKnoxville McGhee Tyson
5h 25m
1 stop
CMH12:30 pmColumbus
Apr 9
CMH1:15 pmColumbus
7h 05m
2 stops
TYS8:20 pmKnoxville McGhee Tyson
$292
Southwest
Apr 7
TYS8:15 amKnoxville McGhee Tyson
10h 05m
2 stops
CMH6:20 pmColumbus
Apr 9
CMH1:15 pmColumbus
7h 05m
2 stops
TYS8:20 pmKnoxville McGhee Tyson
$297
Southwest
Apr 2
TYS6:30 amKnoxville McGhee Tyson
8h 25m
2 stops
CMH2:55 pmColumbus
Apr 7
CMH4:15 pmColumbus
4h 35m
1 stop
TYS8:50 pmKnoxville McGhee Tyson
$311

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Columbus Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 11, 2026.
Use the filters below to find and compare flights from Knoxville to Columbus Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 4/7

7:20 pm-11:40 pm

1 stop4h 20m

Columbus

Thu 4/9

5:30 am-10:08 am

1 stop4h 38m

$287

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 4/2

5:00 am-11:10 am

1 stop6h 10m

Columbus

Tue 4/7

8:44 am-2:22 pm

1 stop5h 38m

$291

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 4/7

7:05 am-12:30 pm

1 stop5h 25m

Columbus

Thu 4/9

1:15 pm-8:20 pm

2 stops7h 05m

$292

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 4/7

8:15 am-6:20 pm

2 stops10h 05m

Columbus

Thu 4/9

1:15 pm-8:20 pm

2 stops7h 05m

$297

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 4/7

2:56 pm-9:41 am

1 stop18h 45m

Columbus

Sun 4/12

8:03 pm-5:30 pm

2 stops21h 27m

$299

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 4/7

5:53 pm-11:59 pm

1 stop6h 06m

Columbus

Sun 4/12

6:04 pm-10:34 pm

1 stop4h 30m

$300

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Mon 4/13

7:00 am-1:12 pm

1 stop6h 12m

Columbus

Fri 4/17

4:10 pm-10:34 pm

1 stop6h 24m

$304

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Fri 4/24

7:30 am-10:32 pm

1 stop15h 02m

Columbus

Sun 4/26

9:42 am-9:57 pm

1 stop12h 15m

$307

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 4/2

6:30 am-2:55 pm

2 stops8h 25m

Columbus

Tue 4/7

4:15 pm-8:50 pm

1 stop4h 35m

$311

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 4/2

6:30 am-2:55 pm

2 stops8h 25m

Columbus

Tue 4/7

1:15 pm-7:40 pm

2 stops6h 25m

$316

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Columbus from

How to get the cheapest flight ticket from Knoxville to Columbus Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Knoxville McGhee Tyson to Columbus?

Southwest, United Airlines, and American Airlines are the most popular carriers operating from Knoxville McGhee Tyson to Columbus

What airlines fly to Columbus Airport?

American Airlines, Delta and United Airlines are the top three most popular airlines that fly to Columbus Airport from Knoxville according to our data. American Airlines is the first choice among our users, with 47% of people opting to fly with this airline when traveling to Columbus Airport. Keep in mind that there are 3 different airlines that fly to Columbus Airport on a routine basis, so you have a few additional options to choose from.

When to book flights from Knoxville to Columbus Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Columbus Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Columbus Airport (TYS to CMH) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Columbus Airport

Fastest flight time

4h 10m

Direct flights

None
The fastest flight from Knoxville to Columbus Airport takes 4h 10m
There are no direct flights from Knoxville to Columbus Airport. There are no popular flight routes from Knoxville to Columbus Airport.
Search flight deals

  • How far is Knoxville McGhee Tyson to Columbus by plane?

    There are 284.5 mi between Knoxville McGhee Tyson and Columbus. In terms of flight time, this usually takes a little over 4h 10m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Columbus Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Columbus Airport are updated daily.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Columbus Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Columbus Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Columbus Airport.

  • What documentation or ID do you need to fly to Columbus Airport?

    The travel and health documents you'll need for your trip to Columbus Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Columbus Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Knoxville to Columbus Airport?

  • What is the most popular airline from Knoxville to Columbus Airport?

Best airlines flying from Knoxville to Columbus Airport

Compare and see reviews for airlines that fly from Knoxville to Columbus Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $218Free CancellationRating
7.9
8,278 reviews
Search Delta flights
American AirlinesPriceFrom $228Free CancellationRating
7.1
11,419 reviews
Search American Airlines flights
United AirlinesPriceFrom $294Free CancellationRating
7.4
9,414 reviews
Search United Airlines flights

Traveling to a place near Columbus?

Book flights to Columbus if you plan to visit one of these locations
Grove City
Reynoldsburg
Hilliard
Chillicothe
Logan
Zanesville
Worthington
Lancaster
Westerville
Bellville
Marysville
Gahanna
Milledgeville

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Columbus?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Columbus from Knoxville.

Can I find flights from Knoxville to Columbus with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Columbus from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Columbus?

Once all potential Knoxville to Columbus flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Knoxville to Columbus right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Columbus from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Columbus Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 4/10
Fri 4/17
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Columbus