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Cheap flights from Knoxville to Istanbul from $545

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Istanbul departing on 10/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Istanbul

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
7:20 pm - 3:30 am
TYS
-
IST
25h 10m
2 stops
Delta Logo
5:55 pm - 11:46 pm
IST
-
TYS
36h 51m
2 stops
$749Delta
Mon, Sep 21 - Wed, Oct 28
Delta Logo
7:20 pm - 3:30 am
TYS
-
IST
25h 10m
2 stops
Delta Logo
4:25 am - 11:46 pm
IST
-
TYS
26h 21m
2 stops
$809Delta
Thu, Sep 24 - Fri, Oct 23
Delta Logo
5:57 pm - 3:30 am
TYS
-
IST
26h 33m
2 stops
Delta Logo
5:55 pm - 6:13 pm
IST
-
TYS
31h 18m
2 stops
$822Delta
Sat, Sep 26 - Wed, Oct 28
British Airways Logo
11:34 am - 6:25 pm
TYS
-
IST
23h 51m
2 stops
British Airways Logo
8:15 am - 11:43 pm
IST
-
TYS
22h 28m
2 stops
$848British Airways
Tue, Aug 11 - Wed, Aug 19
Delta Logo
5:57 pm - 3:30 am
TYS
-
IST
26h 33m
2 stops
Delta Logo
4:25 am - 11:46 pm
IST
-
TYS
26h 21m
2 stops
$859Delta
Sun, Sep 20 - Fri, Oct 23
Delta Logo
7:20 pm - 3:30 am
TYS
-
IST
25h 10m
2 stops
Delta Logo
5:55 pm - 9:45 pm
IST
-
TYS
34h 50m
2 stops
$909Delta
Mon, Sep 21 - Mon, Oct 26
Delta Logo
7:20 pm - 3:30 am
TYS
-
IST
25h 10m
2 stops
Delta Logo
6:00 am - 11:46 pm
IST
-
TYS
24h 46m
2 stops
$954Delta
Mon, Sep 21 - Sat, Oct 24
Delta Logo
5:57 pm - 1:20 am
TYS
-
IST
24h 23m
2 stops
Delta Logo
4:25 am - 10:56 pm
IST
-
TYS
25h 31m
2 stops
$964Delta
Fri, Sep 4 - Sun, Sep 13
Delta Logo
7:20 pm - 3:30 am
TYS
-
IST
25h 10m
2 stops
Delta Logo
5:55 pm - 9:45 pm
IST
-
TYS
34h 50m
2 stops
$969Delta
Thu, Sep 24 - Mon, Oct 26
Delta Logo
5:57 pm - 3:30 am
TYS
-
IST
26h 33m
2 stops
Delta Logo
5:55 pm - 9:45 pm
IST
-
TYS
34h 50m
2 stops
$982Delta
Sat, Sep 26 - Mon, Oct 26

Delta flights from Knoxville to Istanbul Airport

Our best Delta deals on Knoxville to Istanbul Airport flight tickets
Delta
Sep 21
TYS7:20 pmKnoxville McGhee Tyson
25h 10m
2 stops
IST3:30 amIstanbul
Oct 28
IST5:55 pmIstanbul
36h 51m
2 stops
TYS11:46 pmKnoxville McGhee Tyson
$749
Delta
Sep 24
TYS7:20 pmKnoxville McGhee Tyson
25h 10m
2 stops
IST3:30 amIstanbul
Oct 23
IST4:25 amIstanbul
26h 21m
2 stops
TYS11:46 pmKnoxville McGhee Tyson
$809
Delta
Sep 26
TYS5:57 pmKnoxville McGhee Tyson
26h 33m
2 stops
IST3:30 amIstanbul
Oct 28
IST5:55 pmIstanbul
31h 18m
2 stops
TYS6:13 pmKnoxville McGhee Tyson
$822

United Airlines flights from Knoxville to Istanbul Airport

Our best United Airlines deals on Knoxville to Istanbul Airport flight tickets
United Airlines
Sep 24
TYS7:20 pmKnoxville McGhee Tyson
19h 15m
2 stops
IST9:35 pmIstanbul
Oct 27
IST6:30 amIstanbul
24h 07m
2 stops
TYS11:37 pmKnoxville McGhee Tyson
$1,079
United Airlines
Sep 20
TYS6:30 amKnoxville McGhee Tyson
23h 30m
2 stops
IST1:00 pmIstanbul
Oct 27
IST6:30 amIstanbul
24h 07m
2 stops
TYS11:37 pmKnoxville McGhee Tyson
$1,119
United Airlines
Sep 21
TYS7:19 pmKnoxville McGhee Tyson
19h 06m
2 stops
IST9:25 pmIstanbul
Oct 25
IST6:30 amIstanbul
34h 30m
2 stops
TYS10:00 amKnoxville McGhee Tyson
$1,186

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Istanbul Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 8, 2026.
Use the filters below to find and compare flights from Knoxville to Istanbul Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 9/21

7:20 pm-3:30 am

2 stops25h 10m

Istanbul

Wed 10/28

5:55 pm-11:46 pm

2 stops36h 51m

$749

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 9/24

7:20 pm-3:30 am

2 stops25h 10m

Istanbul

Fri 10/23

4:25 am-11:46 pm

2 stops26h 21m

$809

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 9/26

5:57 pm-3:30 am

2 stops26h 33m

Istanbul

Wed 10/28

5:55 pm-6:13 pm

2 stops31h 18m

$822
Quickest round-trip

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Tue 8/11

11:34 am-6:25 pm

2 stops23h 51m

Istanbul

Wed 8/19

8:15 am-11:43 pm

2 stops22h 28m

$848

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sun 9/20

5:57 pm-3:30 am

2 stops26h 33m

Istanbul

Fri 10/23

4:25 am-11:46 pm

2 stops26h 21m

$859

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 9/21

7:20 pm-3:30 am

2 stops25h 10m

Istanbul

Mon 10/26

5:55 pm-9:45 pm

2 stops34h 50m

$909

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Mon 9/21

7:20 pm-3:30 am

2 stops25h 10m

Istanbul

Sat 10/24

6:00 am-11:46 pm

2 stops24h 46m

$954

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Fri 9/4

5:57 pm-1:20 am

2 stops24h 23m

Istanbul

Sun 9/13

4:25 am-10:56 pm

2 stops25h 31m

$964

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Thu 9/24

7:20 pm-3:30 am

2 stops25h 10m

Istanbul

Mon 10/26

5:55 pm-9:45 pm

2 stops34h 50m

$969

KnoxvilleIstanbul

TYS - IST

TYSIST

Knoxville McGhee Tyson

Sat 9/26

5:57 pm-3:30 am

2 stops26h 33m

Istanbul

Mon 10/26

5:55 pm-9:45 pm

2 stops34h 50m

$982

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Istanbul from

How to get the cheapest flight ticket from Knoxville to Istanbul Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Istanbul Airport?

What is the cheapest month to fly to Istanbul Airport?

In general, March is the cheapest month to fly from Knoxville to Istanbul Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you don’t want to visit Istanbul Airport in March, then you should wait until January to fly from Knoxville, when ticket prices are also cheap, with an average price of $0.

When to book flights from Knoxville to Istanbul Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Istanbul Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Istanbul Airport (TYS to IST) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Istanbul Airport

Fastest flight time

18h 26m

Direct flights

None
The fastest flight from Knoxville to Istanbul Airport takes 18h 26m
There are no direct flights from Knoxville to Istanbul Airport. There are no popular flight routes from Knoxville to Istanbul Airport.
Search flight deals

Frequently asked questions about flying from Knoxville to Istanbul Airport

  • How far is Knoxville McGhee Tyson to Istanbul by plane?

    Knoxville McGhee Tyson and Istanbul are 5606.4 mi apart from one another. 18h 26m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Istanbul Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Istanbul Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Istanbul Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Istanbul Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Istanbul Airport.

  • What documentation or ID do you need to fly to Istanbul Airport?

    The travel and health documents you'll need for your trip to Istanbul Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Istanbul Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Istanbul Airport?

Best airlines flying from Knoxville to Istanbul Airport

Compare and see reviews for airlines that fly from Knoxville to Istanbul Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $628Free CancellationRating
7.4
9,694 reviews
Search United Airlines flights
British AirwaysPriceFrom $758Free CancellationRating
6.7
7,952 reviews
Search British Airways flights
American AirlinesPriceFrom $787Free CancellationRating
7.1
11,667 reviews
Search American Airlines flights

Traveling to a place near Istanbul?

Book flights to Istanbul if you plan to visit one of these locations
Yalova

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Istanbul?

Finding the right flight to Istanbul from Knoxville is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Istanbul quick and easy, saving you time and money.

Can I find flights from Knoxville to Istanbul with flexible booking policies on momondo?

All flight searches from Knoxville to Istanbul on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Istanbul?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Istanbul from Knoxville.

I’m not ready to book a flight from Knoxville to Istanbul right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Istanbul from Knoxville. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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