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Cheap flights from Iowa to Panama from $240

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Panama departing on 5/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Iowa to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
1:25 pm - 12:46 pm
DSM
-
PTY
23h 21m
2 stops
American Airlines Logo
1:49 pm - 8:26 am
PTY
-
DSM
18h 37m
2 stops
$570American Airlines
خ, مايو 7 - خ, مايو 14
United Airlines Logo
8:20 am - 4:12 pm
DSM
-
PTY
7h 52m
1 stop
United Airlines Logo
7:55 am - 10:43 pm
PTY
-
DSM
14h 48m
1 stop
$573United Airlines
ن, أبريل 13 - ن, أبريل 20
American Airlines Logo
5:01 pm - 12:46 pm
DSM
-
PTY
19h 45m
2 stops
American Airlines Logo
1:49 pm - 8:26 am
PTY
-
DSM
18h 37m
2 stops
$574American Airlines
خ, مايو 7 - خ, مايو 14
United Airlines Logo
8:20 am - 6:37 pm
DSM
-
PTY
10h 17m
1 stop
United Airlines Logo
10:55 pm - 2:25 pm
PTY
-
DSM
15h 30m
2 stops
$577United Airlines
ن, أبريل 13 - ن, أبريل 20
American Airlines Logo
3:20 pm - 12:46 pm
DSM
-
PTY
21h 26m
2 stops
American Airlines Logo
1:49 pm - 2:47 pm
PTY
-
DSM
24h 58m
2 stops
$579American Airlines
ج, مايو 8 - ج, مايو 15
American Airlines Logo
8:03 pm - 12:46 pm
DSM
-
PTY
16h 43m
2 stops
American Airlines Logo
1:49 pm - 8:26 am
PTY
-
DSM
18h 37m
2 stops
$582American Airlines
ن, مايو 11 - ن, مايو 18
United Airlines Logo
8:15 am - 4:12 pm
DSM
-
PTY
7h 57m
1 stop
United Airlines Logo
7:55 am - 10:45 pm
PTY
-
DSM
14h 50m
1 stop
$585United Airlines
ج, مايو 8 - ج, مايو 15
Delta Logo
5:27 am - 12:50 pm
DSM
-
PTY
7h 23m
1 stop
Delta Logo
2:15 pm - 10:32 pm
PTY
-
DSM
8h 17m
1 stop
$593Delta
ج, مايو 8 - ج, مايو 15
Multiple Airlines Logo
6:01 pm - 4:09 pm
OMA
-
PTY
22h 08m
1 stop
Multiple Airlines Logo
6:02 pm - 7:34 pm
PTY
-
OMA
25h 32m
2 stops
$662Multiple Airlines
ج, مايو 1 - ث, مايو 5
Delta Logo
5:30 am - 1:02 pm
OMA
-
PTY
7h 32m
1 stop
Delta Logo
2:27 pm - 12:10 am
PTY
-
OMA
9h 43m
1 stop
$683Delta
ن, أبريل 13 - خ, أبريل 23

Copa Airlines flights from Iowa to Panama

Our best Copa Airlines deals on Iowa to Panama flight tickets
Copa Airlines
Jun 17
DSM6:00 amDes Moines
12h 37m
2 stops
PTY6:37 pmPanama City Tocumen Intl
Jun 29
PTY3:30 pmPanama City Tocumen Intl
21h 00m
2 stops
DSM12:30 pmDes Moines
$664
Copa Airlines
Apr 17
DSM8:20 amDes Moines
10h 17m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 20
PTY3:30 pmPanama City Tocumen Intl
22h 52m
1 stop
DSM2:22 pmDes Moines
$672
Copa Airlines
Jun 17
DSM6:20 amDes Moines
9h 52m
1 stop
PTY4:12 pmPanama City Tocumen Intl
Jun 29
PTY7:55 amPanama City Tocumen Intl
26h 32m
2 stops
DSM10:27 amDes Moines
$684

American Airlines flights from Iowa to Panama

Our best American Airlines deals on Iowa to Panama flight tickets
American Airlines
May 7
DSM1:25 pmDes Moines
23h 21m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 14
PTY1:49 pmPanama City Tocumen Intl
18h 37m
2 stops
DSM8:26 amDes Moines
$570
American Airlines
May 7
DSM5:01 pmDes Moines
19h 45m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 14
PTY1:49 pmPanama City Tocumen Intl
18h 37m
2 stops
DSM8:26 amDes Moines
$574
American Airlines
May 8
DSM3:20 pmDes Moines
21h 26m
2 stops
PTY12:46 pmPanama City Tocumen Intl
May 15
PTY1:49 pmPanama City Tocumen Intl
24h 58m
2 stops
DSM2:47 pmDes Moines
$579

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated مارس 28, 2026.
Use the filters below to find and compare flights from Iowa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

خ 5/7

1:25 pm-12:46 pm

2 stops23h 21m

Panama City Tocumen Intl

خ 5/14

1:49 pm-8:26 am

2 stops18h 37m

$570

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

ن 4/13

8:20 am-4:12 pm

1 stop7h 52m

Panama City Tocumen Intl

ن 4/20

7:55 am-10:43 pm

1 stop14h 48m

$573

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

خ 5/7

5:01 pm-12:46 pm

2 stops19h 45m

Panama City Tocumen Intl

خ 5/14

1:49 pm-8:26 am

2 stops18h 37m

$574

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

ن 4/13

8:20 am-6:37 pm

1 stop10h 17m

Panama City Tocumen Intl

ن 4/20

10:55 pm-2:25 pm

2 stops15h 30m

$577

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

ج 5/8

3:20 pm-12:46 pm

2 stops21h 26m

Panama City Tocumen Intl

ج 5/15

1:49 pm-2:47 pm

2 stops24h 58m

$579

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

ن 5/11

8:03 pm-12:46 pm

2 stops16h 43m

Panama City Tocumen Intl

ن 5/18

1:49 pm-8:26 am

2 stops18h 37m

$582

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

ج 5/8

8:15 am-4:12 pm

1 stop7h 57m

Panama City Tocumen Intl

ج 5/15

7:55 am-10:45 pm

1 stop14h 50m

$585
Quickest round-trip

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

ج 5/8

5:27 am-12:50 pm

1 stop7h 23m

Panama City Tocumen Intl

ج 5/15

2:15 pm-10:32 pm

1 stop8h 17m

$593

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

ج 5/1

6:01 pm-4:09 pm

1 stop22h 08m

Panama City Tocumen Intl

ث 5/5

6:02 pm-7:34 pm

2 stops25h 32m

$662

OmahaPanama City

OMA - PTY

OMAPTY

Omaha Eppley Airfield

ن 4/13

5:30 am-1:02 pm

1 stop7h 32m

Panama City Tocumen Intl

خ 4/23

2:27 pm-12:10 am

1 stop9h 43m

$683

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Iowa to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of April is, on average, the cheapest month to fly to Panama from Iowa, with most prices found around $436. If you don’t want to visit Panama in April, then you should wait until September to fly from Iowa, when ticket prices are also cheap, with an average price of $441.

Can stopping save me money on Iowa to Panama flights?

You could potentially save up to 13% on your flight if you consider stops on a Iowa to Panama flight.

Cheap Iowa to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Panama

Fastest flight time

7h 23m

Direct flights

None
The fastest flight from Iowa to Panama takes 7h 23m
There are no direct flights from Iowa to Panama. There are no popular flight routes from Iowa to Panama.
Search flight deals

  • When did momondo last update prices for flights from Iowa to Panama?

    Prices for flights from Iowa to Panama are updated daily.

  • How many operators does momondo search for flights from Iowa to Panama?

  • How old do you have to be to fly from Iowa to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Iowa to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Iowa to Panama

Compare and see reviews for airlines that fly from Iowa to Panama with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $364Free CancellationRating
7.9
8,356 reviews
Search Delta flights
United AirlinesPriceFrom $441Free CancellationRating
7.4
9,499 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Iowa to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Iowa to Panama with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Iowa to Panama flights to just show those with flexible booking policies.

How can momondo help me find flights from Iowa to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Iowa.

I’m not ready to book a flight from Iowa to Panama right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama, momondo offers a useful price alert feature which will track prices for flights to Panama from Iowa and alert you when they change.

An easier way to manage your Panama trip

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1 adult
ن 4/27
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