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Cheap flights from Iowa to Panama from $209

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Panama departing on 4/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Iowa to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:44 pm - 3:15 pm
DSM
-
PTY
18h 31m
2 stops
American Airlines Logo
2:40 pm - 9:01 am
PTY
-
DSM
19h 21m
2 stops
$473American Airlines
Sun, Mar 1 - Fri, Mar 6
United Airlines Logo
6:12 am - 6:38 pm
DSM
-
PTY
12h 26m
1 stop
United Airlines Logo
7:55 am - 10:43 pm
PTY
-
DSM
14h 48m
1 stop
$483United Airlines
Sat, Mar 28 - Mon, Apr 20
United Airlines Logo
6:49 pm - 2:14 pm
DSM
-
PTY
19h 25m
2 stops
United Airlines Logo
10:00 am - 10:59 pm
PTY
-
DSM
12h 59m
2 stops
$487United Airlines
Sat, Mar 28 - Wed, Apr 15
United Airlines Logo
7:52 am - 5:07 pm
DSM
-
PTY
8h 15m
1 stop
United Airlines Logo
4:41 pm - 10:20 pm
PTY
-
DSM
30h 39m
1 stop
$492United Airlines
Mon, Feb 23 - Thu, Feb 26
United Airlines Logo
6:55 pm - 5:07 pm
DSM
-
PTY
21h 12m
2 stops
United Airlines Logo
4:41 pm - 10:20 pm
PTY
-
DSM
30h 39m
1 stop
$497United Airlines
Mon, Feb 23 - Thu, Feb 26
United Airlines Logo
3:28 pm - 6:38 pm
DSM
-
PTY
27h 10m
2 stops
United Airlines Logo
10:55 pm - 2:25 pm
PTY
-
DSM
15h 30m
2 stops
$503United Airlines
Thu, Mar 26 - Tue, Apr 21
American Airlines Logo
6:28 pm - 12:45 pm
CID
-
PTY
18h 17m
2 stops
American Airlines Logo
3:51 pm - 12:37 pm
PTY
-
CID
20h 46m
2 stops
$685American Airlines
Thu, Apr 2 - Sun, Apr 5
Delta Logo
5:33 am - 1:50 pm
CID
-
PTY
7h 17m
1 stop
Delta Logo
3:15 pm - 11:38 am
PTY
-
CID
21h 23m
2 stops
$767Delta
Mon, Feb 23 - Mon, Mar 2
Delta Logo
5:32 am - 1:03 pm
CID
-
PTY
7h 31m
1 stop
Delta Logo
2:28 pm - 10:19 pm
PTY
-
CID
7h 51m
1 stop
$1,106Delta
Thu, Apr 2 - Sun, Apr 5
Delta Logo
5:32 am - 1:03 pm
CID
-
PTY
7h 31m
1 stop
Delta Logo
2:28 pm - 10:19 pm
PTY
-
CID
7h 51m
1 stop
$1,288Delta
Thu, Apr 2 - Sun, Apr 5

American Airlines flights from Iowa to Panama

Our best American Airlines deals on Iowa to Panama flight tickets
American Airlines
Mar 1
DSM7:44 pmDes Moines
18h 31m
2 stops
PTY3:15 pmPanama City Tocumen Intl
Mar 6
PTY2:40 pmPanama City Tocumen Intl
19h 21m
2 stops
DSM9:01 amDes Moines
$473
American Airlines
Mar 23
DSM6:00 amDes Moines
8h 20m
1 stop
PTY2:20 pmPanama City Tocumen Intl
Mar 30
PTY3:51 pmPanama City Tocumen Intl
21h 16m
2 stops
DSM1:07 pmDes Moines
$558
American Airlines
Mar 23
DSM6:00 amDes Moines
8h 20m
1 stop
PTY2:20 pmPanama City Tocumen Intl
Mar 30
PTY3:51 pmPanama City Tocumen Intl
21h 27m
2 stops
DSM1:18 pmDes Moines
$560

Copa Airlines flights from Iowa to Panama

Our best Copa Airlines deals on Iowa to Panama flight tickets
Copa Airlines
Feb 9
OMA6:06 amOmaha Eppley Airfield
10h 01m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Feb 19
PTY4:41 pmPanama City Tocumen Intl
24h 36m
2 stops
OMA4:17 pmOmaha Eppley Airfield
$660
Copa Airlines
Feb 20
DSM7:52 amDes Moines
10h 46m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Feb 23
PTY4:41 pmPanama City Tocumen Intl
22h 46m
2 stops
DSM2:27 pmDes Moines
$734
Copa Airlines
Mar 15
OMA9:08 amOmaha Eppley Airfield
28h 37m
2 stops
PTY1:45 pmPanama City Tocumen Intl
Mar 20
PTY3:41 pmPanama City Tocumen Intl
28h 40m
2 stops
OMA8:21 pmOmaha Eppley Airfield
$743

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from Iowa to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sun 3/1

7:44 pm-3:15 pm

2 stops18h 31m

Panama City Tocumen Intl

Fri 3/6

2:40 pm-9:01 am

2 stops19h 21m

$473

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 3/28

6:12 am-6:38 pm

1 stop12h 26m

Panama City Tocumen Intl

Mon 4/20

7:55 am-10:43 pm

1 stop14h 48m

$483

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Sat 3/28

6:49 pm-2:14 pm

2 stops19h 25m

Panama City Tocumen Intl

Wed 4/15

10:00 am-10:59 pm

2 stops12h 59m

$487

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Mon 2/23

7:52 am-5:07 pm

1 stop8h 15m

Panama City Tocumen Intl

Thu 2/26

4:41 pm-10:20 pm

1 stop30h 39m

$492

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Mon 2/23

6:55 pm-5:07 pm

2 stops21h 12m

Panama City Tocumen Intl

Thu 2/26

4:41 pm-10:20 pm

1 stop30h 39m

$497

Des MoinesPanama City

DSM - PTY

DSMPTY

Des Moines

Thu 3/26

3:28 pm-6:38 pm

2 stops27h 10m

Panama City Tocumen Intl

Tue 4/21

10:55 pm-2:25 pm

2 stops15h 30m

$503

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Thu 4/2

6:28 pm-12:45 pm

2 stops18h 17m

Panama City Tocumen Intl

Sun 4/5

3:51 pm-12:37 pm

2 stops20h 46m

$685

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Mon 2/23

5:33 am-1:50 pm

1 stop7h 17m

Panama City Tocumen Intl

Mon 3/2

3:15 pm-11:38 am

2 stops21h 23m

$767

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Thu 4/2

5:32 am-1:03 pm

1 stop7h 31m

Panama City Tocumen Intl

Sun 4/5

2:28 pm-10:19 pm

1 stop7h 51m

$1,106

Cedar RapidsPanama City

CID - PTY

CIDPTY

Cedar Rapids

Thu 4/2

5:32 am-1:03 pm

1 stop7h 31m

Panama City Tocumen Intl

Sun 4/5

2:28 pm-10:19 pm

1 stop7h 51m

$1,288

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Iowa to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from Iowa, with most prices found around $441. If you don’t want to visit Panama in September, then you should wait until January to fly from Iowa, when ticket prices are also cheap, with an average price of $453.

Can stopping save me money on Iowa to Panama flights?

You could potentially save up to 13% on your flight if you consider stops on a Iowa to Panama flight.

Cheap Iowa to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Panama

Fastest flight time

7h 52m

Direct flights

None
The fastest flight from Iowa to Panama takes 7h 52m
There are no direct flights from Iowa to Panama. There are no popular flight routes from Iowa to Panama.
Search flight deals

  • When did momondo last update prices for flights from Iowa to Panama?

    Prices for flights from Iowa to Panama are updated daily.

  • How many operators does momondo search for flights from Iowa to Panama?

  • How old do you have to be to fly from Iowa to Panama?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Iowa to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Iowa to Panama

Compare and see reviews for airlines that fly from Iowa to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $441Free CancellationRating
7.4
9,245 reviews
Search United Airlines flights
DeltaPriceFrom $441Free CancellationRating
7.9
8,162 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Iowa to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Iowa to Panama with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Iowa to Panama flights to just show those with flexible booking policies.

How can momondo help me find flights from Iowa to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Iowa.

I’m not ready to book a flight from Iowa to Panama right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama, momondo offers a useful price alert feature which will track prices for flights to Panama from Iowa and alert you when they change.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
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