Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Indianapolis to Panama from $232

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to Panama departing on 12/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Indianapolis to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
9:00 am - 5:07 pmIND-PTY
8h 07m1 stop
United Airlines Logo
9:30 am - 8:49 pmPTY-IND
10h 19m1 stop
$490United Airlines
Find Deal
Thu, Mar 5 - Tue, Mar 10
United Airlines Logo
6:00 am - 8:02 pmIND-PTY
14h 02m2 stops
United Airlines Logo
3:41 pm - 10:59 amPTY-IND
18h 18m2 stops
$494United Airlines
Find Deal
Thu, Mar 5 - Tue, Mar 10
Delta Logo
4:15 pm - 12:55 pmIND-PTY
21h 40m1 stop
Delta Logo
2:20 pm - 9:00 amPTY-IND
17h 40m1 stop
$498Delta
Find Deal
Sun, Mar 8 - Thu, Mar 12
United Airlines Logo
5:05 pm - 2:45 pmIND-PTY
21h 40m1 stop
United Airlines Logo
4:41 pm - 10:48 amPTY-IND
18h 07m1 stop
$499United Airlines
Find Deal
Sun, Jan 4 - Tue, Jan 13
American Airlines Logo
7:06 pm - 3:38 pmIND-PTY
20h 32m1 stop
American Airlines Logo
2:27 pm - 11:32 amPTY-IND
21h 05m2 stops
$506American Airlines
Find Deal
Thu, Jan 15 - Tue, Jan 20
United Airlines Logo
11:35 am - 7:38 pmIND-PTY
8h 03m1 stop
United Airlines Logo
9:30 am - 8:49 pmPTY-IND
10h 19m1 stop
$510United Airlines
Find Deal
Sat, Mar 7 - Tue, Mar 10
American Airlines Logo
8:18 pm - 2:20 pmIND-PTY
19h 02m2 stops
American Airlines Logo
1:50 pm - 1:14 pmPTY-IND
22h 24m2 stops
$514American Airlines
Find Deal
Sat, Mar 21 - Tue, Mar 31
Multiple Airlines Logo
11:51 am - 2:55 pmIND-PTY
27h 04m3 stops
Multiple Airlines Logo
11:25 am - 7:43 amPTY-IND
20h 18m3 stops
$616Multiple Airlines
Find Deal
Thu, Nov 27 - Wed, Dec 3
Multiple Airlines Logo
5:30 am - 1:00 amIND-PTY
19h 30m2 stops
Multiple Airlines Logo
2:55 am - 9:35 pmPTY-IND
18h 40m2 stops
$627Multiple Airlines
Find Deal
Sat, Dec 6 - Fri, Dec 12
Copa Airlines Logo
6:00 am - 2:00 pmIND-PTY
9h 00m1 stop
Copa Airlines Logo
7:40 pm - 9:21 amPTY-IND
12h 41m1 stop
$694Copa Airlines
Find Deal
Sat, Mar 21 - Thu, Apr 2

American Airlines flights from Indianapolis to Panama

Our best American Airlines deals on Indianapolis to Panama flight tickets
American Airlines
Jan 15
IND7:06 pmIndianapolis
20h 32m
1 stop
PTY3:38 pmPanama City Tocumen Intl
Jan 20
PTY2:27 pmPanama City Tocumen Intl
21h 05m
2 stops
IND11:32 amIndianapolis
$506
Find similar
American Airlines
Mar 21
IND8:18 pmIndianapolis
19h 02m
2 stops
PTY2:20 pmPanama City Tocumen Intl
Mar 31
PTY1:50 pmPanama City Tocumen Intl
22h 24m
2 stops
IND1:14 pmIndianapolis
$514
Find similar
American Airlines
Feb 24
IND6:00 amIndianapolis
7h 40m
1 stop
PTY1:40 pmPanama City Tocumen Intl
Mar 1
PTY4:04 pmPanama City Tocumen Intl
18h 13m
1 stop
IND10:17 amIndianapolis
$515
Find similar

United Airlines flights from Indianapolis to Panama

Our best United Airlines deals on Indianapolis to Panama flight tickets
United Airlines
Mar 5
IND9:00 amIndianapolis
8h 07m
1 stop
PTY5:07 pmPanama City Tocumen Intl
Mar 10
PTY9:30 amPanama City Tocumen Intl
10h 19m
1 stop
IND8:49 pmIndianapolis
$490
Find similar
United Airlines
Mar 5
IND6:00 amIndianapolis
14h 02m
2 stops
PTY8:02 pmPanama City Tocumen Intl
Mar 10
PTY3:41 pmPanama City Tocumen Intl
18h 18m
2 stops
IND10:59 amIndianapolis
$494
Find similar
United Airlines
Jan 4
IND5:05 pmIndianapolis
21h 40m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Jan 13
PTY4:41 pmPanama City Tocumen Intl
18h 07m
1 stop
IND10:48 amIndianapolis
$499
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 3/5

9:00 am-5:07 pm

1 stop8h 07m

Panama City Tocumen Intl

Tue 3/10

9:30 am-8:49 pm

1 stop10h 19m

$490

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 3/5

6:00 am-8:02 pm

2 stops14h 02m

Panama City Tocumen Intl

Tue 3/10

3:41 pm-10:59 am

2 stops18h 18m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sun 3/8

4:15 pm-12:55 pm

1 stop21h 40m

Panama City Tocumen Intl

Thu 3/12

2:20 pm-9:00 am

1 stop17h 40m

$498

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sun 1/4

5:05 pm-2:45 pm

1 stop21h 40m

Panama City Tocumen Intl

Tue 1/13

4:41 pm-10:48 am

1 stop18h 07m

$499

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 1/15

7:06 pm-3:38 pm

1 stop20h 32m

Panama City Tocumen Intl

Tue 1/20

2:27 pm-11:32 am

2 stops21h 05m

$506

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 3/7

11:35 am-7:38 pm

1 stop8h 03m

Panama City Tocumen Intl

Tue 3/10

9:30 am-8:49 pm

1 stop10h 19m

$510

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 3/21

8:18 pm-2:20 pm

2 stops19h 02m

Panama City Tocumen Intl

Tue 3/31

1:50 pm-1:14 pm

2 stops22h 24m

$514

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 11/27

11:51 am-2:55 pm

3 stops27h 04m

Panama City Tocumen Intl

Wed 12/3

11:25 am-7:43 am

3 stops20h 18m

$616

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 12/6

5:30 am-1:00 am

2 stops19h 30m

Panama City Tocumen Intl

Fri 12/12

2:55 am-9:35 pm

2 stops18h 40m

$627

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 3/21

6:00 am-2:00 pm

1 stop9h 00m

Panama City Tocumen Intl

Thu 4/2

7:40 pm-9:21 am

1 stop12h 41m

$694

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

See travel insights to Panama from

How to get the cheapest flight ticket from Indianapolis to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from Indianapolis, with most prices found around $489. If you don’t want to visit Panama in September, then you should wait until July to fly from Indianapolis, when ticket prices are also cheap, with an average price of $509.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Indianapolis. The lowest ticket price found for a Tuesday departure recently was $491. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Indianapolis to Panama for around $623.

What is the cheapest time of day to depart on your flight to Panama?

In the afternoon is the cheapest time of day to fly from Indianapolis to Panama when you can find flight prices for as low as $543. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $589 per ticket.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $608 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Indianapolis for as low as $491 on momondo.

Can stopping save me money on Indianapolis to Panama flights?

You could potentially save up to 51% on your flight if you consider stops on a Indianapolis to Panama flight.

Cheap Indianapolis to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to Panama

Direct flights

None
There are no direct flights from Indianapolis to Panama. There are no popular flight routes from Indianapolis to Panama.
Search flight deals

  • When did momondo last update prices for flights from Indianapolis Airport to Panama?

    Prices for flights from Indianapolis Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Indianapolis Airport to Panama?

  • How old do you have to be to fly from Indianapolis Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indianapolis Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Indianapolis to Panama

Compare and see reviews for airlines that fly from Indianapolis to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $463Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
United AirlinesPriceFrom $469Free CancellationRating
7.4
9,007 reviews
Search United Airlines flights
DeltaPriceFrom $473Free CancellationRating
7.9
8,001 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to Panama?

Finding the right flight to Panama from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama quick and easy, saving you time and money.

Can I find flights from Indianapolis to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Indianapolis with this policy.

How can momondo help me find flights from Indianapolis to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Indianapolis.

I’m not ready to book a flight from Indianapolis to Panama right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama, momondo offers a useful price alert feature which will track prices for flights to Panama from Indianapolis and alert you when they change.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 12/6
Sat 12/13
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo
Flights to Panama Cityfrom $250
Flights to Bocas del Torofrom $685
Flights to Davidfrom $359
Flights to Changuinola