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Cheap flights from Indianapolis to Panama from $307

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to Panama departing on 2/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Indianapolis to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:43 pm - 12:46 pm
IND
-
PTY
18h 03m
2 stops
American Airlines Logo
1:49 pm - 11:46 am
PTY
-
IND
20h 57m
2 stops
$431American Airlines
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
7:43 pm - 12:46 pm
IND
-
PTY
18h 03m
2 stops
American Airlines Logo
1:49 pm - 11:26 am
PTY
-
IND
20h 37m
1 stop
$441American Airlines
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
6:00 am - 2:20 pm
IND
-
PTY
9h 20m
1 stop
American Airlines Logo
3:51 pm - 10:04 am
PTY
-
IND
17h 13m
1 stop
$467American Airlines
Tue, Mar 24 - Wed, Apr 1
American Airlines Logo
6:01 am - 12:46 pm
IND
-
PTY
7h 45m
1 stop
American Airlines Logo
1:49 pm - 11:26 am
PTY
-
IND
20h 37m
1 stop
$469American Airlines
Tue, Apr 21 - Tue, Apr 28
American Airlines Logo
9:30 pm - 2:20 pm
IND
-
PTY
17h 50m
2 stops
American Airlines Logo
3:51 pm - 1:26 pm
PTY
-
IND
20h 35m
2 stops
$471American Airlines
Tue, Mar 24 - Wed, Apr 1
American Airlines Logo
4:49 pm - 12:40 pm
IND
-
PTY
20h 51m
2 stops
American Airlines Logo
1:40 pm - 10:42 am
PTY
-
IND
20h 02m
2 stops
$490American Airlines
Sat, Mar 21 - Thu, Apr 2
American Airlines Logo
5:30 pm - 12:40 pm
IND
-
PTY
20h 10m
2 stops
American Airlines Logo
1:49 pm - 10:18 am
PTY
-
IND
19h 29m
2 stops
$505American Airlines
Sat, Mar 28 - Wed, Apr 8
American Airlines Logo
5:30 pm - 12:46 pm
IND
-
PTY
20h 16m
2 stops
American Airlines Logo
1:49 pm - 10:45 am
PTY
-
IND
19h 56m
2 stops
$506American Airlines
Mon, Apr 6 - Wed, May 6
United Airlines Logo
9:24 am - 6:37 pm
IND
-
PTY
10h 13m
1 stop
United Airlines Logo
10:00 am - 8:06 pm
PTY
-
IND
9h 06m
1 stop
$511United Airlines
Mon, Apr 6 - Wed, May 6
American Airlines Logo
5:30 pm - 12:40 pm
IND
-
PTY
20h 10m
2 stops
American Airlines Logo
1:49 pm - 11:26 am
PTY
-
IND
20h 37m
1 stop
$515American Airlines
Sat, Mar 28 - Wed, Apr 8

United Airlines flights from Indianapolis to Panama

Our best United Airlines deals on Indianapolis to Panama flight tickets
United Airlines
Apr 6
IND9:24 amIndianapolis
10h 13m
1 stop
PTY6:37 pmPanama City Tocumen Intl
May 6
PTY10:00 amPanama City Tocumen Intl
9h 06m
1 stop
IND8:06 pmIndianapolis
$511
United Airlines
Mar 24
IND9:00 amIndianapolis
8h 07m
1 stop
PTY4:07 pmPanama City Tocumen Intl
Apr 1
PTY9:45 amPanama City Tocumen Intl
9h 48m
1 stop
IND8:33 pmIndianapolis
$531
United Airlines
Mar 24
IND7:15 amIndianapolis
12h 23m
2 stops
PTY6:38 pmPanama City Tocumen Intl
Apr 1
PTY3:30 pmPanama City Tocumen Intl
18h 16m
1 stop
IND10:46 amIndianapolis
$535

American Airlines flights from Indianapolis to Panama

Our best American Airlines deals on Indianapolis to Panama flight tickets
American Airlines
Apr 21
IND7:43 pmIndianapolis
18h 03m
2 stops
PTY12:46 pmPanama City Tocumen Intl
Apr 28
PTY1:49 pmPanama City Tocumen Intl
20h 57m
2 stops
IND11:46 amIndianapolis
$431
American Airlines
Apr 21
IND7:43 pmIndianapolis
18h 03m
2 stops
PTY12:46 pmPanama City Tocumen Intl
Apr 28
PTY1:49 pmPanama City Tocumen Intl
20h 37m
1 stop
IND11:26 amIndianapolis
$441
American Airlines
Mar 24
IND6:00 amIndianapolis
9h 20m
1 stop
PTY2:20 pmPanama City Tocumen Intl
Apr 1
PTY3:51 pmPanama City Tocumen Intl
17h 13m
1 stop
IND10:04 amIndianapolis
$467

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 4/21

7:43 pm-12:46 pm

2 stops18h 03m

Panama City Tocumen Intl

Tue 4/28

1:49 pm-11:46 am

2 stops20h 57m

$431

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 4/21

7:43 pm-12:46 pm

2 stops18h 03m

Panama City Tocumen Intl

Tue 4/28

1:49 pm-11:26 am

1 stop20h 37m

$441

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/24

6:00 am-2:20 pm

1 stop9h 20m

Panama City Tocumen Intl

Wed 4/1

3:51 pm-10:04 am

1 stop17h 13m

$467

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 4/21

6:01 am-12:46 pm

1 stop7h 45m

Panama City Tocumen Intl

Tue 4/28

1:49 pm-11:26 am

1 stop20h 37m

$469

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/24

9:30 pm-2:20 pm

2 stops17h 50m

Panama City Tocumen Intl

Wed 4/1

3:51 pm-1:26 pm

2 stops20h 35m

$471

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 3/21

4:49 pm-12:40 pm

2 stops20h 51m

Panama City Tocumen Intl

Thu 4/2

1:40 pm-10:42 am

2 stops20h 02m

$490

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 3/28

5:30 pm-12:40 pm

2 stops20h 10m

Panama City Tocumen Intl

Wed 4/8

1:49 pm-10:18 am

2 stops19h 29m

$505

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 4/6

5:30 pm-12:46 pm

2 stops20h 16m

Panama City Tocumen Intl

Wed 5/6

1:49 pm-10:45 am

2 stops19h 56m

$506

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 4/6

9:24 am-6:37 pm

1 stop10h 13m

Panama City Tocumen Intl

Wed 5/6

10:00 am-8:06 pm

1 stop9h 06m

$511

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 3/28

5:30 pm-12:40 pm

2 stops20h 10m

Panama City Tocumen Intl

Wed 4/8

1:49 pm-11:26 am

1 stop20h 37m

$515

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Indianapolis to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from Indianapolis, with most prices found around $489. If you don’t want to visit Panama in September, then you should wait until July to fly from Indianapolis, when ticket prices are also cheap, with an average price of $509.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $646 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Indianapolis for as low as $493 on momondo.

Can stopping save me money on Indianapolis to Panama flights?

You could potentially save up to 47% on your flight if you consider stops on a Indianapolis to Panama flight.

Cheap Indianapolis to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to Panama

Fastest flight time

7h 54m

Direct flights

None
The fastest flight from Indianapolis to Panama takes 7h 54m
There are no direct flights from Indianapolis to Panama. There are no popular flight routes from Indianapolis to Panama.
Search flight deals

  • When did momondo last update prices for flights from Indianapolis Airport to Panama?

    Prices for flights from Indianapolis Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Indianapolis Airport to Panama?

  • How old do you have to be to fly from Indianapolis Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indianapolis Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Indianapolis to Panama

Compare and see reviews for airlines that fly from Indianapolis to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $463Free CancellationRating
7.2
11,248 reviews
Search American Airlines flights
United AirlinesPriceFrom $469Free CancellationRating
7.4
9,250 reviews
Search United Airlines flights
DeltaPriceFrom $473Free CancellationRating
7.9
8,169 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to Panama?

Finding the right flight to Panama from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama quick and easy, saving you time and money.

Can I find flights from Indianapolis to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Indianapolis with this policy.

How can momondo help me find flights from Indianapolis to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Indianapolis.

I’m not ready to book a flight from Indianapolis to Panama right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama, momondo offers a useful price alert feature which will track prices for flights to Panama from Indianapolis and alert you when they change.

An easier way to manage your Panama trip

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