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Cheap flights from Indianapolis to Panama from $252

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to Panama departing on 11/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

United Airlines Logo
7:00 am - 6:37 pmIND-PTY
12h 37m1 stop
United Airlines Logo
10:00 am - 11:30 pmPTY-IND
12h 30m1 stop
$489United Airlines
Find Deal
Wed, Oct 8 - Mon, Oct 20
American Airlines Logo
6:00 am - 2:00 pmIND-PTY
9h 00m2 stops
American Airlines Logo
3:15 pm - 12:17 pmPTY-IND
20h 02m2 stops
$494American Airlines
Find Deal
Wed, Oct 22 - Wed, Oct 29
American Airlines Logo
6:25 pm - 1:36 pmIND-PTY
19h 11m2 stops
American Airlines Logo
2:43 pm - 9:52 amPTY-IND
19h 09m2 stops
$499American Airlines
Find Deal
Tue, Nov 4 - Fri, Nov 7
United Airlines Logo
7:00 am - 2:14 pmIND-PTY
8h 14m1 stop
United Airlines Logo
10:00 am - 11:30 pmPTY-IND
12h 30m1 stop
$509United Airlines
Find Deal
Fri, Oct 10 - Tue, Oct 21
American Airlines Logo
1:59 pm - 1:36 pmIND-PTY
23h 37m2 stops
American Airlines Logo
2:43 pm - 11:54 pmPTY-IND
9h 11m1 stop
$514American Airlines
Find Deal
Sat, Nov 8 - Wed, Nov 12
United Airlines Logo
5:22 pm - 6:38 pmIND-PTY
26h 16m1 stop
United Airlines Logo
4:41 pm - 10:53 amPTY-IND
18h 12m1 stop
$519United Airlines
Find Deal
Fri, Oct 31 - Mon, Nov 3
Logo
5:30 am - 9:00 pmIND-PTY
15h 30m2 stops
Logo
3:19 am - 10:56 pmPTY-IND
19h 37m2 stops
$520
Find Deal
Tue, Nov 4 - Thu, Nov 6
United Airlines Logo
5:22 pm - 6:38 pmIND-PTY
26h 16m1 stop
United Airlines Logo
4:41 pm - 1:12 pmPTY-IND
20h 31m2 stops
$524United Airlines
Find Deal
Fri, Oct 31 - Mon, Nov 3
United Airlines Logo
7:00 am - 6:37 pmIND-PTY
12h 37m1 stop
United Airlines Logo
3:30 pm - 11:02 amPTY-IND
18h 32m1 stop
$529United Airlines
Find Deal
Thu, Sep 4 - Mon, Sep 8
Delta Logo
7:15 am - 12:50 pmIND-PTY
6h 35m1 stop
Delta Logo
2:05 pm - 12:08 amPTY-IND
9h 03m1 stop
$549Delta
Find Deal
Mon, Sep 1 - Fri, Sep 5

American Airlines flights from Indianapolis to Panama

Our best American Airlines deals on Indianapolis to Panama flight tickets
American Airlines
Oct 22
IND6:00 amIndianapolis
9h 00m
2 stops
PTY2:00 pmPanama City Tocumen Intl
Oct 29
PTY3:15 pmPanama City Tocumen Intl
20h 02m
2 stops
IND12:17 pmIndianapolis
$494
Find similar
American Airlines
Nov 4
IND6:25 pmIndianapolis
19h 11m
2 stops
PTY1:36 pmPanama City Tocumen Intl
Nov 7
PTY2:43 pmPanama City Tocumen Intl
19h 09m
2 stops
IND9:52 amIndianapolis
$499
Find similar
American Airlines
Nov 8
IND1:59 pmIndianapolis
23h 37m
2 stops
PTY1:36 pmPanama City Tocumen Intl
Nov 12
PTY2:43 pmPanama City Tocumen Intl
9h 11m
1 stop
IND11:54 pmIndianapolis
$514
Find similar

United Airlines flights from Indianapolis to Panama

Our best United Airlines deals on Indianapolis to Panama flight tickets
United Airlines
Oct 8
IND7:00 amIndianapolis
12h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Oct 20
PTY10:00 amPanama City Tocumen Intl
12h 30m
1 stop
IND11:30 pmIndianapolis
$489
Find similar
United Airlines
Oct 10
IND7:00 amIndianapolis
8h 14m
1 stop
PTY2:14 pmPanama City Tocumen Intl
Oct 21
PTY10:00 amPanama City Tocumen Intl
12h 30m
1 stop
IND11:30 pmIndianapolis
$509
Find similar
United Airlines
Oct 31
IND5:22 pmIndianapolis
26h 16m
1 stop
PTY6:38 pmPanama City Tocumen Intl
Nov 3
PTY4:41 pmPanama City Tocumen Intl
18h 12m
1 stop
IND10:53 amIndianapolis
$519
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 1, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 10/8

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Mon 10/20

10:00 am-11:30 pm

1 stop12h 30m

$489

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 10/22

6:00 am-2:00 pm

2 stops9h 00m

Panama City Tocumen Intl

Wed 10/29

3:15 pm-12:17 pm

2 stops20h 02m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 11/4

6:25 pm-1:36 pm

2 stops19h 11m

Panama City Tocumen Intl

Fri 11/7

2:43 pm-9:52 am

2 stops19h 09m

$499

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 10/10

7:00 am-2:14 pm

1 stop8h 14m

Panama City Tocumen Intl

Tue 10/21

10:00 am-11:30 pm

1 stop12h 30m

$509

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 11/8

1:59 pm-1:36 pm

2 stops23h 37m

Panama City Tocumen Intl

Wed 11/12

2:43 pm-11:54 pm

1 stop9h 11m

$514

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 10/31

5:22 pm-6:38 pm

1 stop26h 16m

Panama City Tocumen Intl

Mon 11/3

4:41 pm-10:53 am

1 stop18h 12m

$519

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 11/4

5:30 am-9:00 pm

2 stops15h 30m

Panama City Tocumen Intl

Thu 11/6

3:19 am-10:56 pm

2 stops19h 37m

$520

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 10/31

5:22 pm-6:38 pm

1 stop26h 16m

Panama City Tocumen Intl

Mon 11/3

4:41 pm-1:12 pm

2 stops20h 31m

$524

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 9/4

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Mon 9/8

3:30 pm-11:02 am

1 stop18h 32m

$529

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Mon 9/1

7:15 am-12:50 pm

1 stop6h 35m

Panama City Tocumen Intl

Fri 9/5

2:05 pm-12:08 am

1 stop9h 03m

$549

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 16 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Indianapolis to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of October is, on average, the cheapest month to fly to Panama from Indianapolis, with most prices found around $497. If you don’t want to visit Panama in October, then you should wait until July to fly from Indianapolis, when ticket prices are also cheap, with an average price of $509.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Indianapolis. The lowest ticket price found for a Tuesday departure recently was $491. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Indianapolis to Panama for around $623.

What is the cheapest time of day to depart on your flight to Panama?

In the afternoon is the cheapest time of day to fly from Indianapolis to Panama when you can find flight prices for as low as $543. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $589 per ticket.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $589 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Indianapolis for as low as $502 on momondo.

Cheap Indianapolis to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to Panama

Best Price Found

$252

Fastest flight time

6h 35m

Direct flights

None

Airports in Panama

1 airport
The best one-way flight to Panama from Indianapolis in the past 72 hours is $252. The best round-trip flight deal from Indianapolis to Panama found on momondo in the last 72 hours is $489.
The fastest flight from Indianapolis to Panama takes 6h 35m
There are no direct flights from Indianapolis to Panama. Popular non-direct route for this connection is Indianapolis Airport - Panama City Tocumen Intl Airport.
There is 1 airport near Panama: Panama City Tocumen Intl (PTY)
Search flight deals

  • When did momondo last update prices for flights from Indianapolis Airport to Panama?

    Prices for flights from Indianapolis Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Indianapolis Airport to Panama?

  • How old do you have to be to fly from Indianapolis Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indianapolis Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Indianapolis to Panama

Compare and see reviews for airlines that fly from Indianapolis to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $463Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $469Free CancellationRating
7.4
8,900 reviews
Search United Airlines flights
DeltaPriceFrom $469Free CancellationRating
8.0
7,981 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to Panama?

Finding the right flight to Panama from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama quick and easy, saving you time and money.

Can I find flights from Indianapolis to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Indianapolis with this policy.

How can momondo help me find flights from Indianapolis to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Indianapolis.

I’m not ready to book a flight from Indianapolis to Panama right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama, momondo offers a useful price alert feature which will track prices for flights to Panama from Indianapolis and alert you when they change.

An easier way to manage your Panama trip

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