Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Indianapolis to Panama from $221

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Indianapolis to Panama departing on 11/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Indianapolis to Panama

Cheap round-trip flights

Multiple Airlines Logo
10:15 am - 9:10 pmIND-PTY
11h 55m2 stops
Multiple Airlines Logo
2:55 am - 7:43 pmPTY-IND
15h 48m2 stops
$387Multiple Airlines
Find Deal
Sat, Oct 25 - Tue, Oct 28
Multiple Airlines Logo
10:15 am - 9:10 pmIND-PTY
11h 55m2 stops
Multiple Airlines Logo
2:55 am - 7:43 pmPTY-IND
15h 48m2 stops
$388Multiple Airlines
Find Deal
Sat, Oct 25 - Mon, Oct 27
Multiple Airlines Logo
6:35 am - 8:19 pmIND-PTY
13h 44m1 stop
Multiple Airlines Logo
12:03 pm - 10:56 pmPTY-IND
10h 53m1 stop
$445Multiple Airlines
Find Deal
Tue, Nov 11 - Thu, Nov 20
Multiple Airlines Logo
6:35 am - 8:19 pmIND-PTY
13h 44m1 stop
Multiple Airlines Logo
12:03 pm - 10:56 pmPTY-IND
10h 53m1 stop
$450Multiple Airlines
Find Deal
Tue, Nov 11 - Tue, Nov 18
Delta Logo
6:00 am - 12:55 pmIND-PTY
7h 55m1 stop
Delta Logo
2:20 pm - 11:57 pmPTY-IND
8h 37m1 stop
$489Delta
Find Deal
Tue, Mar 10 - Thu, Mar 12
United Airlines Logo
7:37 am - 6:38 pmIND-PTY
12h 01m2 stops
United Airlines Logo
3:40 pm - 9:21 amPTY-IND
16h 41m2 stops
$494United Airlines
Find Deal
Tue, Mar 10 - Thu, Mar 12
American Airlines Logo
4:46 pm - 1:10 pmIND-PTY
20h 24m2 stops
American Airlines Logo
2:45 pm - 10:49 amPTY-IND
20h 04m2 stops
$499American Airlines
Find Deal
Wed, Jan 14 - Wed, Jan 21
American Airlines Logo
7:12 pm - 1:49 pmIND-PTY
18h 37m1 stop
American Airlines Logo
2:49 pm - 11:56 pmPTY-IND
9h 07m1 stop
$501American Airlines
Find Deal
Tue, Nov 4 - Fri, Nov 7
United Airlines Logo
9:00 am - 7:38 pmIND-PTY
10h 38m1 stop
United Airlines Logo
8:55 am - 11:44 pmPTY-IND
14h 49m1 stop
$509United Airlines
Find Deal
Fri, Nov 14 - Mon, Nov 17
Delta Logo
7:00 am - 12:56 pmIND-PTY
6h 56m1 stop
Delta Logo
2:21 pm - 12:22 amPTY-IND
9h 01m1 stop
$529Delta
Find Deal
Thu, Oct 16 - Tue, Oct 28

American Airlines flights from Indianapolis to Panama

Our best American Airlines deals on Indianapolis to Panama flight tickets
American Airlines
Jan 14
IND4:46 pmIndianapolis
20h 24m
2 stops
PTY1:10 pmPanama City Tocumen Intl
Jan 21
PTY2:45 pmPanama City Tocumen Intl
20h 04m
2 stops
IND10:49 amIndianapolis
$499
Find similar
American Airlines
Nov 4
IND7:12 pmIndianapolis
18h 37m
1 stop
PTY1:49 pmPanama City Tocumen Intl
Nov 7
PTY2:49 pmPanama City Tocumen Intl
9h 07m
1 stop
IND11:56 pmIndianapolis
$501
Find similar
American Airlines
Nov 4
IND7:43 pmIndianapolis
18h 06m
2 stops
PTY1:49 pmPanama City Tocumen Intl
Nov 8
PTY2:49 pmPanama City Tocumen Intl
18h 58m
2 stops
IND9:47 amIndianapolis
$514
Find similar

United Airlines flights from Indianapolis to Panama

Our best United Airlines deals on Indianapolis to Panama flight tickets
United Airlines
Mar 10
IND7:37 amIndianapolis
12h 01m
2 stops
PTY6:38 pmPanama City Tocumen Intl
Mar 12
PTY3:40 pmPanama City Tocumen Intl
16h 41m
2 stops
IND9:21 amIndianapolis
$494
Find similar
United Airlines
Nov 14
IND9:00 amIndianapolis
10h 38m
1 stop
PTY7:38 pmPanama City Tocumen Intl
Nov 17
PTY8:55 amPanama City Tocumen Intl
14h 49m
1 stop
IND11:44 pmIndianapolis
$509
Find similar
United Airlines
Nov 8
IND5:22 pmIndianapolis
21h 23m
1 stop
PTY2:45 pmPanama City Tocumen Intl
Nov 12
PTY8:55 amPanama City Tocumen Intl
14h 49m
1 stop
IND11:44 pmIndianapolis
$519
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Indianapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Indianapolis to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 10/25

10:15 am-9:10 pm

2 stops11h 55m

Panama City Tocumen Intl

Tue 10/28

2:55 am-7:43 pm

2 stops15h 48m

$387

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Sat 10/25

10:15 am-9:10 pm

2 stops11h 55m

Panama City Tocumen Intl

Mon 10/27

2:55 am-7:43 pm

2 stops15h 48m

$388

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 11/11

6:35 am-8:19 pm

1 stop13h 44m

Panama City Tocumen Intl

Thu 11/20

12:03 pm-10:56 pm

1 stop10h 53m

$445

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 11/11

6:35 am-8:19 pm

1 stop13h 44m

Panama City Tocumen Intl

Tue 11/18

12:03 pm-10:56 pm

1 stop10h 53m

$450

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/10

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 3/12

2:20 pm-11:57 pm

1 stop8h 37m

$489

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 3/10

7:37 am-6:38 pm

2 stops12h 01m

Panama City Tocumen Intl

Thu 3/12

3:40 pm-9:21 am

2 stops16h 41m

$494

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Wed 1/14

4:46 pm-1:10 pm

2 stops20h 24m

Panama City Tocumen Intl

Wed 1/21

2:45 pm-10:49 am

2 stops20h 04m

$499

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Tue 11/4

7:12 pm-1:49 pm

1 stop18h 37m

Panama City Tocumen Intl

Fri 11/7

2:49 pm-11:56 pm

1 stop9h 07m

$501

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Fri 11/14

9:00 am-7:38 pm

1 stop10h 38m

Panama City Tocumen Intl

Mon 11/17

8:55 am-11:44 pm

1 stop14h 49m

$509

IndianapolisPanama City

IND - PTY

INDPTY

Indianapolis

Thu 10/16

7:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

Tue 10/28

2:21 pm-12:22 am

1 stop9h 01m

$529

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

See travel insights to Panama from

How to get the cheapest flight ticket from Indianapolis to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of July is, on average, the cheapest month to fly to Panama from Indianapolis, with most prices found around $509. If you don’t want to visit Panama in July, then you should wait until May to fly from Indianapolis, when ticket prices are also cheap, with an average price of $519.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Indianapolis. The lowest ticket price found for a Tuesday departure recently was $491. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Indianapolis to Panama for around $623.

What is the cheapest time of day to depart on your flight to Panama?

In the afternoon is the cheapest time of day to fly from Indianapolis to Panama when you can find flight prices for as low as $543. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $589 per ticket.

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Indianapolis when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $604 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Indianapolis for as low as $488 on momondo.

Cheap Indianapolis to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Indianapolis to Panama

Direct flights

None
There are no direct flights from Indianapolis to Panama. There are no popular flight routes from Indianapolis to Panama.
Search flight deals

  • When did momondo last update prices for flights from Indianapolis Airport to Panama?

    Prices for flights from Indianapolis Airport to Panama refresh daily.

  • How many operators does momondo search for flights from Indianapolis Airport to Panama?

  • How old do you have to be to fly from Indianapolis Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Indianapolis Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The required travel and health documents for your Panama trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Indianapolis to Panama

Compare and see reviews for airlines that fly from Indianapolis to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $463Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $469Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
DeltaPriceFrom $489Free CancellationRating
7.9
7,961 reviews
Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Indianapolis to Panama?

Finding the right flight to Panama from Indianapolis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Panama quick and easy, saving you time and money.

Can I find flights from Indianapolis to Panama with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Panama from Indianapolis with this policy.

How can momondo help me find flights from Indianapolis to Panama?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Panama from Indianapolis.

I’m not ready to book a flight from Indianapolis to Panama right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Panama, momondo offers a useful price alert feature which will track prices for flights to Panama from Indianapolis and alert you when they change.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Fri 10/17
Fri 10/24
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo
Flights to Panama Cityfrom $248
Flights to Bocas del Torofrom $516
Flights to Davidfrom $296
Flights to Changuinola