Cheap flights from Houston to Panama from $190

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Panama departing on 1/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:20 pm - 2:00 pm
IAH
-
PTY
20h 40m2 stops
Multiple Airlines Logo
7:50 pm - 3:08 pm
PTY
-
IAH
20h 18m2 stops
$456Multiple Airlines
Thu, Jan 22 - Mon, Jan 26
Multiple Airlines Logo
7:30 am - 6:55 pm
IAH
-
PTY
10h 25m1 stop
Multiple Airlines Logo
3:50 pm - 2:37 pm
PTY
-
IAH
23h 47m1 stop
$470Multiple Airlines
Mon, Jan 12 - Tue, Jan 20
Multiple Airlines Logo
3:56 pm - 8:50 am
IAH
-
PTY
15h 54m2 stops
Multiple Airlines Logo
9:45 pm - 5:17 pm
PTY
-
IAH
20h 32m1 stop
$482Multiple Airlines
Mon, Jan 19 - Mon, Jan 26
Multiple Airlines Logo
4:20 pm - 8:50 am
IAH
-
PTY
15h 30m2 stops
Multiple Airlines Logo
7:50 pm - 11:05 am
PTY
-
IAH
16h 15m1 stop
$485Multiple Airlines
Thu, Jan 22 - Mon, Jan 26
Delta Logo
5:45 am - 1:55 pm
HOU
-
PTY
7h 10m1 stop
Delta Logo
3:20 pm - 4:10 pm
PTY
-
HOU
25h 50m1 stop
$745Delta
Mon, Jan 19 - Mon, Jan 26
Delta Logo
6:00 am - 12:55 pm
HOU
-
PTY
6h 55m1 stop
Delta Logo
2:20 pm - 10:28 pm
PTY
-
HOU
8h 08m1 stop
$754Delta
Tue, Mar 10 - Wed, Mar 18
American Airlines Logo
6:36 pm - 3:38 pm
HOU
-
PTY
20h 02m2 stops
American Airlines Logo
2:27 pm - 10:05 am
PTY
-
HOU
20h 38m2 stops
$758American Airlines
Wed, Jan 7 - Wed, Jan 14
Delta Logo
5:27 pm - 12:55 pm
HOU
-
PTY
19h 28m1 stop
Delta Logo
2:20 pm - 10:28 pm
PTY
-
HOU
8h 08m1 stop
$765Delta
Wed, Mar 11 - Wed, Mar 18
American Airlines Logo
4:55 pm - 1:27 pm
HOU
-
PTY
19h 32m2 stops
American Airlines Logo
5:00 pm - 10:05 am
PTY
-
HOU
18h 05m2 stops
$778American Airlines
Tue, Jan 6 - Sat, Jan 24
American Airlines Logo
4:55 pm - 1:27 pm
HOU
-
PTY
19h 32m2 stops
American Airlines Logo
4:50 pm - 10:05 am
PTY
-
HOU
18h 15m2 stops
$779American Airlines
Fri, Jan 23 - Fri, Jan 30

American Airlines flights from Houston to Panama

Our best American Airlines deals on Houston to Panama flight tickets
American Airlines
Jan 7
HOU6:36 pmHouston Hobby
20h 02m
2 stops
PTY3:38 pmPanama City Tocumen Intl
Jan 14
PTY2:27 pmPanama City Tocumen Intl
20h 38m
2 stops
HOU10:05 amHouston Hobby
American Airlines
Jan 6
HOU4:55 pmHouston Hobby
19h 32m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Jan 24
PTY5:00 pmPanama City Tocumen Intl
18h 05m
2 stops
HOU10:05 amHouston Hobby
American Airlines
Jan 23
HOU4:55 pmHouston Hobby
19h 32m
2 stops
PTY1:27 pmPanama City Tocumen Intl
Jan 30
PTY4:50 pmPanama City Tocumen Intl
18h 15m
2 stops
HOU10:05 amHouston Hobby

Delta flights from Houston to Panama

Our best Delta deals on Houston to Panama flight tickets
Delta
Jan 19
HOU5:45 amHouston Hobby
7h 10m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Jan 26
PTY3:20 pmPanama City Tocumen Intl
25h 50m
1 stop
HOU4:10 pmHouston Hobby
Delta
Mar 10
HOU6:00 amHouston Hobby
6h 55m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Mar 18
PTY2:20 pmPanama City Tocumen Intl
8h 08m
1 stop
HOU10:28 pmHouston Hobby
Delta
Mar 11
HOU5:27 pmHouston Hobby
19h 28m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Mar 18
PTY2:20 pmPanama City Tocumen Intl
8h 08m
1 stop
HOU10:28 pmHouston Hobby

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Houston to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Thu 1/22

4:20 pm-2:00 pm

2 stops20h 40m

Panama City Tocumen Intl

Mon 1/26

7:50 pm-3:08 pm

2 stops20h 18m

$456

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Mon 1/12

7:30 am-6:55 pm

1 stop10h 25m

Panama City Tocumen Intl

Tue 1/20

3:50 pm-2:37 pm

1 stop23h 47m

$470

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Mon 1/19

3:56 pm-8:50 am

2 stops15h 54m

Panama City Tocumen Intl

Mon 1/26

9:45 pm-5:17 pm

1 stop20h 32m

$482

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

Thu 1/22

4:20 pm-8:50 am

2 stops15h 30m

Panama City Tocumen Intl

Mon 1/26

7:50 pm-11:05 am

1 stop16h 15m

$485

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Mon 1/19

5:45 am-1:55 pm

1 stop7h 10m

Panama City Tocumen Intl

Mon 1/26

3:20 pm-4:10 pm

1 stop25h 50m

$745

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 3/10

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Wed 3/18

2:20 pm-10:28 pm

1 stop8h 08m

$754

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Wed 1/7

6:36 pm-3:38 pm

2 stops20h 02m

Panama City Tocumen Intl

Wed 1/14

2:27 pm-10:05 am

2 stops20h 38m

$758

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Wed 3/11

5:27 pm-12:55 pm

1 stop19h 28m

Panama City Tocumen Intl

Wed 3/18

2:20 pm-10:28 pm

1 stop8h 08m

$765

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Tue 1/6

4:55 pm-1:27 pm

2 stops19h 32m

Panama City Tocumen Intl

Sat 1/24

5:00 pm-10:05 am

2 stops18h 05m

$778

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

Fri 1/23

4:55 pm-1:27 pm

2 stops19h 32m

Panama City Tocumen Intl

Fri 1/30

4:50 pm-10:05 am

2 stops18h 15m

$779

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Panama from

How to get the cheapest flight ticket from Houston to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of January is, on average, the cheapest month to fly to Panama from Houston, with most prices found around $788. If you don’t want to visit Panama in January, then you should wait until May to fly from Houston, when ticket prices are also cheap, with an average price of $858.

What is the cheapest day to depart on your flight to Panama?

According to our data, Saturday is the cheapest day to fly to Panama from Houston. The lowest ticket price found for a Saturday departure recently was $802. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Houston to Panama for around $1,137.

What is the cheapest time of day to depart on your flight to Panama?

In the afternoon is the cheapest time of day to fly from Houston to Panama when you can find flight prices for as low as $467. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $908 per ticket.

What is the cheapest Houston to Panama flight route?

Fly from Houston George Bush Intcntl to Panama City Tocumen Intl for the best Houston - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Houston when booking week ahead of your departure date. In general, you can expect to find flights to Panama for around $902 when searching week out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Houston for as low as $733 on momondo.

What cabin class options are available on Houston to Panama flights?

There are 3 cabin classes available to choose from on Houston to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Panama

Fastest flight time

4h 11m

Direct flights

Every day

Airports in Panama

21 airports
The fastest flight from Houston to Panama takes 4h 11m
Direct flights go from Houston to Panama every day.
There are 21 airports in Panama. From Houston there are direct flights to Panama City Tocumen Intl (PTY).
  • When did momondo last update prices for flights from Houston to Panama?

    Prices for flights from Houston to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to Panama?

  • How old do you have to be to fly from Houston to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Houston to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Panama

Compare and see reviews for airlines that fly from Houston to Panama with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $318Free CancellationRating
6.6
2,480 reviews
Search Avianca flights
United AirlinesPriceFrom $738Free CancellationRating
7.4
9,095 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $846Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Houston to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Houston to Panama with flexible booking policies on momondo?

All flight searches from Houston to Panama on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Houston to Panama?

Once you have performed a search for Houston to Panama flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Houston to Panama right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Panama flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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1 adult
Sat 1/10
Sat 1/17

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