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Cheap flights from Houston to Panama from $165

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Houston to Panama departing on 10/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Houston to Panama

Cheap round-trip flights

Logo
12:47 pm - 8:19 pmIAH-PTY
7h 32m1 stop
Logo
12:03 pm - 10:42 pmPTY-IAH
10h 39m1 stop
$412
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lun., sep. 29 - jue., oct. 2
Logo
10:55 am - 7:20 pmIAH-PTY
8h 25m1 stop
Logo
9:33 pm - 10:00 amPTY-IAH
13h 27m1 stop
$415
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vie., oct. 31 - dom., nov. 2
Logo
10:55 am - 7:29 pmIAH-PTY
8h 34m1 stop
Logo
9:33 pm - 10:00 amPTY-IAH
12h 27m1 stop
$419
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lun., oct. 20 - jue., oct. 23
Logo
5:45 am - 12:35 pmIAH-PTY
30h 50m3 stops
Logo
10:05 pm - 9:17 pmPTY-IAH
23h 12m3 stops
$429
Find Deal
jue., oct. 16 - lun., oct. 20
Delta Logo
6:00 am - 12:56 pmHOU-PTY
6h 56m1 stop
Delta Logo
3:21 pm - 11:00 pmPTY-HOU
8h 39m1 stop
$743Delta
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mar., oct. 28 - mar., nov. 4
American Airlines Logo
6:39 pm - 2:03 pmHOU-PTY
19h 24m2 stops
American Airlines Logo
3:15 pm - 8:28 amPTY-HOU
17h 13m2 stops
$758American Airlines
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mar., oct. 14 - vie., oct. 24
Delta Logo
6:00 am - 12:56 pmHOU-PTY
6h 56m1 stop
Delta Logo
2:21 pm - 11:00 pmPTY-HOU
8h 39m1 stop
$768Delta
Find Deal
mar., oct. 14 - vie., oct. 24
American Airlines Logo
6:07 pm - 1:53 pmHOU-PTY
18h 46m2 stops
American Airlines Logo
2:45 pm - 8:38 amPTY-HOU
18h 53m2 stops
$778American Airlines
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sáb., ene. 3 - mar., feb. 3
American Airlines Logo
8:19 pm - 1:48 pmHOU-PTY
16h 29m2 stops
American Airlines Logo
4:37 pm - 9:38 amPTY-HOU
18h 01m2 stops
$783American Airlines
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jue., dic. 4 - dom., dic. 14
Delta Logo
6:00 am - 12:56 pmHOU-PTY
6h 56m1 stop
Delta Logo
2:21 pm - 11:00 pmPTY-HOU
8h 39m1 stop
$893Delta
Find Deal
jue., oct. 16 - lun., oct. 20

American Airlines flights from Houston to Panama

Our best American Airlines deals on Houston to Panama flight tickets
American Airlines
Oct 14
HOU6:39 pmHouston Hobby
19h 24m
2 stops
PTY2:03 pmPanama City Tocumen Intl
Oct 24
PTY3:15 pmPanama City Tocumen Intl
17h 13m
2 stops
HOU8:28 amHouston Hobby
$758
Find similar
American Airlines
Jan 3
HOU6:07 pmHouston Hobby
18h 46m
2 stops
PTY1:53 pmPanama City Tocumen Intl
Feb 3
PTY2:45 pmPanama City Tocumen Intl
18h 53m
2 stops
HOU8:38 amHouston Hobby
$778
Find similar
American Airlines
Dec 4
HOU8:19 pmHouston Hobby
16h 29m
2 stops
PTY1:48 pmPanama City Tocumen Intl
Dec 14
PTY4:37 pmPanama City Tocumen Intl
18h 01m
2 stops
HOU9:38 amHouston Hobby
$783
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Delta flights from Houston to Panama

Our best Delta deals on Houston to Panama flight tickets
Delta
Oct 28
HOU6:00 amHouston Hobby
6h 56m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Nov 4
PTY3:21 pmPanama City Tocumen Intl
8h 39m
1 stop
HOU11:00 pmHouston Hobby
$743
Find similar
Delta
Oct 14
HOU6:00 amHouston Hobby
6h 56m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 24
PTY2:21 pmPanama City Tocumen Intl
8h 39m
1 stop
HOU11:00 pmHouston Hobby
$768
Find similar
Delta
Oct 16
HOU6:00 amHouston Hobby
6h 56m
1 stop
PTY12:56 pmPanama City Tocumen Intl
Oct 20
PTY2:21 pmPanama City Tocumen Intl
8h 39m
1 stop
HOU11:00 pmHouston Hobby
$893
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Houston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Houston to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

lun. 9/29

12:47 pm-8:19 pm

1 stop7h 32m

Panama City Tocumen Intl

jue. 10/2

12:03 pm-10:42 pm

1 stop10h 39m

$412

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

vie. 10/31

10:55 am-7:20 pm

1 stop8h 25m

Panama City Tocumen Intl

dom. 11/2

9:33 pm-10:00 am

1 stop13h 27m

$415

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

lun. 10/20

10:55 am-7:29 pm

1 stop8h 34m

Panama City Tocumen Intl

jue. 10/23

9:33 pm-10:00 am

1 stop12h 27m

$419

HoustonPanama City

IAH - PTY

IAHPTY

Houston George Bush Intcntl

jue. 10/16

5:45 am-12:35 pm

3 stops30h 50m

Panama City Tocumen Intl

lun. 10/20

10:05 pm-9:17 pm

3 stops23h 12m

$429

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

mar. 10/28

6:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

mar. 11/4

3:21 pm-11:00 pm

1 stop8h 39m

$743

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

mar. 10/14

6:39 pm-2:03 pm

2 stops19h 24m

Panama City Tocumen Intl

vie. 10/24

3:15 pm-8:28 am

2 stops17h 13m

$758

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

mar. 10/14

6:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

vie. 10/24

2:21 pm-11:00 pm

1 stop8h 39m

$768

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

sáb. 1/3

6:07 pm-1:53 pm

2 stops18h 46m

Panama City Tocumen Intl

mar. 2/3

2:45 pm-8:38 am

2 stops18h 53m

$778

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

jue. 12/4

8:19 pm-1:48 pm

2 stops16h 29m

Panama City Tocumen Intl

dom. 12/14

4:37 pm-9:38 am

2 stops18h 01m

$783

HoustonPanama City

HOU - PTY

HOUPTY

Houston Hobby

jue. 10/16

6:00 am-12:56 pm

1 stop6h 56m

Panama City Tocumen Intl

lun. 10/20

2:21 pm-11:00 pm

1 stop8h 39m

$893

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Houston to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of January is, on average, the cheapest month to fly to Panama from Houston, with most prices found around $788. If you don’t want to visit Panama in January, then you should wait until June to fly from Houston, when ticket prices are also cheap, with an average price of $845.

What is the cheapest day to depart on your flight to Panama?

According to our data, Saturday is the cheapest day to fly to Panama from Houston. The lowest ticket price found for a Saturday departure recently was $802. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Houston to Panama for around $1,137.

What is the cheapest time of day to depart on your flight to Panama?

In the afternoon is the cheapest time of day to fly from Houston to Panama when you can find flight prices for as low as $467. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $1,018 per ticket.

What is the cheapest Houston to Panama flight route?

Fly from Houston George Bush Intcntl to Panama City Tocumen Intl for the best Houston - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Houston when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $897 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Houston for as low as $435 on momondo.

What cabin class options are available on Houston to Panama flights?

There are 3 cabin classes available to choose from on Houston to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Houston to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Houston to Panama

Fastest flight time

4h 11m

Direct flights

Every day

Airports in Panama

1 airport
The fastest flight from Houston to Panama takes 4h 11m
Direct flights go from Houston to Panama every day.
There is 1 airport near Panama: Panama City Tocumen Intl (PTY)
Search flight deals

  • When did momondo last update prices for flights from Houston to Panama?

    Prices for flights from Houston to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from Houston to Panama?

  • How old do you have to be to fly from Houston to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Houston to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Houston to Panama

Compare and see reviews for airlines that fly from Houston to Panama with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $318Free CancellationRating
6.7
2,435 reviews
Search Avianca flights
United AirlinesPriceFrom $738Free CancellationRating
7.4
8,929 reviews
Search United Airlines flights
Copa AirlinesPriceFrom $824Free CancellationRating
7.6
1,531 reviews
Search Copa Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Houston to Panama?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Houston to Panama. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Houston to Panama with flexible booking policies on momondo?

All flight searches from Houston to Panama on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Houston to Panama?

Once you have performed a search for Houston to Panama flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Houston to Panama right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Houston to Panama flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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