Cheap flights from Houston to Panama from $333

The month of March is, on average, the cheapest month to fly to Panama from Houston, with most prices found around $814. If you don’t want to visit Panama in March, then you should wait until January to fly from Houston, when ticket prices are also cheap, with an average price of $835.

At noon is the cheapest time of day to fly from Houston to Panama when you can find flight prices for as low as $980. Flying to Panama at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $1,016 per ticket.

Fly from Houston George Bush Intcntl to Panama City Tocumen Intl for the best Houston - Panama flight prices

There are 3 cabin classes available to choose from on Houston to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Historically, on average around 15% of flights between Houston and Panama have experienced a delay on any given week. The average delay length over the past 12 months has been 113 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Friday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

According to our data, United Airlines have had the least number of delays on this route over the last 12 months; with about 15% of their flights experiencing any sort of delay.

The number of flights available between Houston and Panama is 4 per day as of November 2026. The most frequent departure time is 9:00AM, with 50% of daily flights leaving at noon.

The number of flights available between Houston and Panama is 28 per week as of November 2026. The most frequent departure day is Mon, with 14% of weekly flights leaving on this day.