Cheap flights from Houston to Panama from $207

The month of April is, on average, the cheapest month to fly to Panama from Houston, with most prices found around $452. If you don’t want to visit Panama in April, then you should wait until September to fly from Houston, when ticket prices are also cheap, with an average price of $483.

At noon is the cheapest time of day to fly from Houston to Panama when you can find flight prices for as low as $830. Flying to Panama at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $912 per ticket.

Fly from Houston George Bush Intcntl to Panama City Tocumen Intl for the best Houston - Panama flight prices

You are more likely to see cheaper flights to Panama from Houston when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $912 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Houston for as low as $636 on momondo.

Delta and Avianca are the most popular carriers operating from Houston to Panama

United Airlines, Copa Airlines and JetBlue are the top three most popular airlines that fly to Panama from Houston according to our data. United Airlines is the first choice among our users, with 79% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

Historically, on average around 18% of flights between Houston and Panama have experienced a delay on any given week. The average delay length over the past 12 months has been 139 minutes.

Generally, flights departing at night tend to experience fewer delays. Flights in the morning have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, United Airlines have had the least number of delays on this route over the last 12 months; with about 18% of their flights experiencing any sort of delay.

The number of flights available between Houston and Panama is 6 per day as of May 2026. The most frequent departure time is 9:00AM, with 66% of daily flights leaving at noon.

The number of flights available between Houston and Panama is 42 per week as of May 2026. The most frequent departure day is Mon, with 14% of weekly flights leaving on this day.