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Cheap flights from Florence, South Carolina to Chicago from $173

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Florence, South Carolina to Chicago departing on 6/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Florence, South Carolina to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
4:02 pm - 7:22 pm
FLO
-
ORD
4h 20m
1 stop
American Airlines Logo
4:17 pm - 10:42 pm
ORD
-
FLO
5h 25m
1 stop
$309American Airlines
Tue, Apr 28 - Tue, May 5
American Airlines Logo
6:15 am - 10:11 am
FLO
-
ORD
4h 56m
1 stop
American Airlines Logo
1:54 pm - 9:47 pm
ORD
-
FLO
6h 53m
1 stop
$339American Airlines
Tue, Apr 14 - Sat, Apr 18
American Airlines Logo
5:20 am - 10:11 am
FLO
-
ORD
5h 51m
1 stop
American Airlines Logo
4:17 pm - 9:47 pm
ORD
-
FLO
4h 30m
1 stop
$343American Airlines
Fri, May 1 - Fri, May 8
American Airlines Logo
6:15 am - 10:11 am
FLO
-
ORD
4h 56m
1 stop
American Airlines Logo
12:42 pm - 9:47 pm
ORD
-
FLO
8h 05m
2 stops
$344American Airlines
Tue, Apr 14 - Sat, Apr 18
American Airlines Logo
5:20 am - 10:44 am
FLO
-
ORD
6h 24m
1 stop
American Airlines Logo
4:17 pm - 9:47 pm
ORD
-
FLO
4h 30m
1 stop
$357American Airlines
Thu, Apr 16 - Mon, Apr 20
American Airlines Logo
5:20 am - 10:44 am
FLO
-
ORD
6h 24m
1 stop
American Airlines Logo
8:39 am - 3:32 pm
ORD
-
FLO
5h 53m
1 stop
$380American Airlines
Fri, Apr 17 - Tue, Apr 21
American Airlines Logo
5:20 am - 10:14 am
FLO
-
ORD
5h 54m
1 stop
American Airlines Logo
8:39 am - 3:50 pm
ORD
-
FLO
6h 11m
1 stop
$411American Airlines
Fri, Apr 24 - Mon, Apr 27
American Airlines Logo
5:20 am - 10:11 am
FLO
-
ORD
5h 51m
1 stop
American Airlines Logo
1:54 pm - 9:47 pm
ORD
-
FLO
6h 53m
1 stop
$431American Airlines
Thu, Apr 16 - Mon, Apr 20
American Airlines Logo
5:20 am - 8:30 am
FLO
-
ORD
4h 10m
1 stop
American Airlines Logo
1:25 pm - 9:47 pm
ORD
-
FLO
7h 22m
2 stops
$599American Airlines
Thu, Apr 16 - Mon, Apr 20
American Airlines Logo
5:20 am - 10:11 am
FLO
-
ORD
5h 51m
1 stop
American Airlines Logo
1:25 pm - 9:47 pm
ORD
-
FLO
7h 22m
2 stops
$634American Airlines
Fri, May 1 - Fri, May 8

American Airlines flights from Florence, South Carolina to Chicago O'Hare Intl Airport

Our best American Airlines deals on Florence, South Carolina to Chicago O'Hare Intl Airport flight tickets
American Airlines
Apr 28
FLO4:02 pmFlorence
4h 20m
1 stop
ORD7:22 pmChicago O'Hare Intl
May 5
ORD4:17 pmChicago O'Hare Intl
5h 25m
1 stop
FLO10:42 pmFlorence
$309
American Airlines
Apr 14
FLO6:15 amFlorence
4h 56m
1 stop
ORD10:11 amChicago O'Hare Intl
Apr 18
ORD1:54 pmChicago O'Hare Intl
6h 53m
1 stop
FLO9:47 pmFlorence
$339
American Airlines
May 1
FLO5:20 amFlorence
5h 51m
1 stop
ORD10:11 amChicago O'Hare Intl
May 8
ORD4:17 pmChicago O'Hare Intl
4h 30m
1 stop
FLO9:47 pmFlorence
$343

momondo Fare Finder

 
Customize your flight search to find flights from Florence, South Carolina to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 4, 2026.
Use the filters below to find and compare flights from Florence, South Carolina to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

FlorenceChicago

FLO - ORD

FLOORD

Florence

Tue 4/28

4:02 pm-7:22 pm

1 stop4h 20m

Chicago O'Hare Intl

Tue 5/5

4:17 pm-10:42 pm

1 stop5h 25m

$309

FlorenceChicago

FLO - ORD

FLOORD

Florence

Tue 4/14

6:15 am-10:11 am

1 stop4h 56m

Chicago O'Hare Intl

Sat 4/18

1:54 pm-9:47 pm

1 stop6h 53m

$339

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 5/1

5:20 am-10:11 am

1 stop5h 51m

Chicago O'Hare Intl

Fri 5/8

4:17 pm-9:47 pm

1 stop4h 30m

$343

FlorenceChicago

FLO - ORD

FLOORD

Florence

Tue 4/14

6:15 am-10:11 am

1 stop4h 56m

Chicago O'Hare Intl

Sat 4/18

12:42 pm-9:47 pm

2 stops8h 05m

$344

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 4/16

5:20 am-10:44 am

1 stop6h 24m

Chicago O'Hare Intl

Mon 4/20

4:17 pm-9:47 pm

1 stop4h 30m

$357

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 4/17

5:20 am-10:44 am

1 stop6h 24m

Chicago O'Hare Intl

Tue 4/21

8:39 am-3:32 pm

1 stop5h 53m

$380

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 4/24

5:20 am-10:14 am

1 stop5h 54m

Chicago O'Hare Intl

Mon 4/27

8:39 am-3:50 pm

1 stop6h 11m

$411

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 4/16

5:20 am-10:11 am

1 stop5h 51m

Chicago O'Hare Intl

Mon 4/20

1:54 pm-9:47 pm

1 stop6h 53m

$431

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 4/16

5:20 am-8:30 am

1 stop4h 10m

Chicago O'Hare Intl

Mon 4/20

1:25 pm-9:47 pm

2 stops7h 22m

$599

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 5/1

5:20 am-10:11 am

1 stop5h 51m

Chicago O'Hare Intl

Fri 5/8

1:25 pm-9:47 pm

2 stops7h 22m

$634

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Florence, South Carolina to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Florence, South Carolina to Chicago O'Hare Intl Airport flights?

You could potentially save up to 45% on your flight if you consider stops on a Florence, South Carolina to Chicago O'Hare Intl Airport flight.

When to book flights from Florence, South Carolina to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Florence, South Carolina to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Florence, South Carolina to Chicago O'Hare Intl Airport (FLO to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to Chicago O'Hare Intl Airport

Fastest flight time

5h 51m

Direct flights

None
The fastest flight from Florence, South Carolina to Chicago O'Hare Intl Airport takes 5h 51m
There are no direct flights from Florence, South Carolina to Chicago O'Hare Intl Airport. There are no popular flight routes from Florence, South Carolina to Chicago O'Hare Intl Airport.
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Frequently asked questions about flying from Florence, South Carolina to Chicago O'Hare Intl Airport

  • How far is Florence to Chicago O'Hare Intl by plane?

    A flight from Florence to Chicago O'Hare Intl will travel around 695.4 mi. Typically, this will take 5h 51m by plane in normal conditions.

  • When did momondo last update prices for flights from Florence Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Florence Airport to Chicago O'Hare Intl Airport refresh daily.

  • How many operators does momondo search for flights from Florence Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Florence Airport to Chicago O'Hare Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Florence Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The necessary travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Florence, South Carolina to Chicago O'Hare Intl Airport?

Best airlines flying from Florence, South Carolina to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Florence, South Carolina to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $176Free CancellationRating
7.1
11,556 reviews
Search American Airlines flights

Traveling to a place near Chicago?

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Why use momondo?

Why should I use momondo to find a flight deal from Florence to Chicago?

Finding the right flight to Chicago from Florence is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Chicago quick and easy, saving you time and money.

Can I find flights from Florence to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Florence which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Florence to Chicago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Chicago from Florence.

I’m not ready to book a flight from Florence to Chicago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Chicago from Florence. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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