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Cheap flights from Florence, South Carolina to Chicago from $433

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Florence, South Carolina to Chicago departing on 10/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
6:14 am - 10:32 amFLO-ORD
5h 18m1 stop
American Airlines Logo
5:00 am - 10:47 amORD-FLO
4h 47m1 stop
$433American Airlines
Find Deal
Fri, Oct 31 - Tue, Nov 4
American Airlines Logo
6:14 am - 10:32 amFLO-ORD
5h 18m1 stop
American Airlines Logo
10:29 am - 5:09 pmORD-FLO
5h 40m1 stop
$437American Airlines
Find Deal
Thu, Oct 30 - Mon, Nov 3
American Airlines Logo
6:14 am - 9:30 amFLO-ORD
4h 16m1 stop
American Airlines Logo
2:50 pm - 10:53 pmORD-FLO
7h 03m2 stops
$438American Airlines
Find Deal
Fri, Oct 31 - Tue, Nov 4
American Airlines Logo
6:14 am - 11:06 amFLO-ORD
5h 52m2 stops
American Airlines Logo
3:44 pm - 10:53 pmORD-FLO
6h 09m1 stop
$442American Airlines
Find Deal
Thu, Oct 30 - Mon, Nov 3
American Airlines Logo
6:14 am - 1:43 pmFLO-ORD
8h 29m2 stops
American Airlines Logo
2:50 pm - 10:53 pmORD-FLO
7h 03m2 stops
$443American Airlines
Find Deal
Fri, Oct 31 - Tue, Nov 4
American Airlines Logo
6:14 am - 12:03 pmFLO-ORD
6h 49m2 stops
American Airlines Logo
9:53 am - 5:09 pmORD-FLO
6h 16m2 stops
$447American Airlines
Find Deal
Thu, Oct 30 - Mon, Nov 3
American Airlines Logo
6:15 am - 12:28 pmFLO-ORD
7h 13m1 stop
American Airlines Logo
12:16 pm - 10:53 pmORD-FLO
9h 37m2 stops
$453American Airlines
Find Deal
Mon, Nov 24 - Tue, Dec 2
American Airlines Logo
6:15 am - 12:28 pmFLO-ORD
7h 13m2 stops
American Airlines Logo
12:16 pm - 10:53 pmORD-FLO
9h 37m2 stops
$458American Airlines
Find Deal
Mon, Nov 24 - Tue, Dec 2
American Airlines Logo
2:33 pm - 5:54 pmFLO-ORD
4h 21m1 stop
American Airlines Logo
5:36 pm - 11:29 pmORD-FLO
4h 53m1 stop
$463American Airlines
Find Deal
Wed, Mar 4 - Sat, Mar 7
American Airlines Logo
6:52 am - 6:00 pmFLO-ORD
12h 08m2 stops
American Airlines Logo
8:16 am - 2:03 pmORD-FLO
4h 47m1 stop
$466American Airlines
Find Deal
Wed, Mar 4 - Sat, Mar 7

American Airlines flights from Florence, South Carolina to Chicago O'Hare Intl Airport

Our best American Airlines deals on Florence, South Carolina to Chicago O'Hare Intl Airport flight tickets
American Airlines
Oct 31
FLO6:14 amFlorence
5h 18m
1 stop
ORD10:32 amChicago O'Hare Intl
Nov 4
ORD5:00 amChicago O'Hare Intl
4h 47m
1 stop
FLO10:47 amFlorence
$433
Find similar
American Airlines
Oct 30
FLO6:14 amFlorence
5h 18m
1 stop
ORD10:32 amChicago O'Hare Intl
Nov 3
ORD10:29 amChicago O'Hare Intl
5h 40m
1 stop
FLO5:09 pmFlorence
$437
Find similar
American Airlines
Oct 31
FLO6:14 amFlorence
4h 16m
1 stop
ORD9:30 amChicago O'Hare Intl
Nov 4
ORD2:50 pmChicago O'Hare Intl
7h 03m
2 stops
FLO10:53 pmFlorence
$438
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Florence, South Carolina to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Florence, South Carolina to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 10/31

6:14 am-10:32 am

1 stop5h 18m

Chicago O'Hare Intl

Tue 11/4

5:00 am-10:47 am

1 stop4h 47m

$433

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 10/30

6:14 am-10:32 am

1 stop5h 18m

Chicago O'Hare Intl

Mon 11/3

10:29 am-5:09 pm

1 stop5h 40m

$437

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 10/31

6:14 am-9:30 am

1 stop4h 16m

Chicago O'Hare Intl

Tue 11/4

2:50 pm-10:53 pm

2 stops7h 03m

$438

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 10/30

6:14 am-11:06 am

2 stops5h 52m

Chicago O'Hare Intl

Mon 11/3

3:44 pm-10:53 pm

1 stop6h 09m

$442

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 10/31

6:14 am-1:43 pm

2 stops8h 29m

Chicago O'Hare Intl

Tue 11/4

2:50 pm-10:53 pm

2 stops7h 03m

$443

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 10/30

6:14 am-12:03 pm

2 stops6h 49m

Chicago O'Hare Intl

Mon 11/3

9:53 am-5:09 pm

2 stops6h 16m

$447

FlorenceChicago

FLO - ORD

FLOORD

Florence

Mon 11/24

6:15 am-12:28 pm

1 stop7h 13m

Chicago O'Hare Intl

Tue 12/2

12:16 pm-10:53 pm

2 stops9h 37m

$453

FlorenceChicago

FLO - ORD

FLOORD

Florence

Mon 11/24

6:15 am-12:28 pm

2 stops7h 13m

Chicago O'Hare Intl

Tue 12/2

12:16 pm-10:53 pm

2 stops9h 37m

$458

FlorenceChicago

FLO - ORD

FLOORD

Florence

Wed 3/4

2:33 pm-5:54 pm

1 stop4h 21m

Chicago O'Hare Intl

Sat 3/7

5:36 pm-11:29 pm

1 stop4h 53m

$463

FlorenceChicago

FLO - ORD

FLOORD

Florence

Wed 3/4

6:52 am-6:00 pm

2 stops12h 08m

Chicago O'Hare Intl

Sat 3/7

8:16 am-2:03 pm

1 stop4h 47m

$466

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

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How to get the cheapest flight ticket from Florence, South Carolina to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Florence, South Carolina to Chicago O'Hare Intl Airport flights?

You could potentially save up to 15% on your flight if you consider stops on a Florence, South Carolina to Chicago O'Hare Intl Airport flight.

When to book flights from Florence, South Carolina to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Florence, South Carolina to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Florence, South Carolina to Chicago O'Hare Intl Airport (FLO to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to Chicago O'Hare Intl Airport

Direct flights

None
There are no direct flights from Florence, South Carolina to Chicago O'Hare Intl Airport. There are no popular flight routes from Florence, South Carolina to Chicago O'Hare Intl Airport.
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  • How far is Florence to Chicago O'Hare Intl by plane?

    A flight from Florence to Chicago O'Hare Intl will travel around 695.4 mi. Typically, this will take 4h 16m by plane in normal conditions.

  • When did momondo last update prices for flights from Florence Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Florence Airport to Chicago O'Hare Intl Airport refresh daily.

  • How many operators does momondo search for flights from Florence Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Florence Airport to Chicago O'Hare Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Florence Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The necessary travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Florence, South Carolina to Chicago O'Hare Intl Airport?

Best airlines flying from Florence, South Carolina to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Florence, South Carolina to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $176Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights

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Why should I use momondo to find a flight deal from Florence to Chicago?

Finding the right flight to Chicago from Florence is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Chicago quick and easy, saving you time and money.

Can I find flights from Florence to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Florence which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Florence to Chicago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Chicago from Florence.

I’m not ready to book a flight from Florence to Chicago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Chicago from Florence. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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