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Cheap flights from Florence, South Carolina to Chicago from $209

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Florence, South Carolina to Chicago departing on 9/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Florence, South Carolina to Chicago (FLO-ORD)

Cheap round-trip flights

American Airlines Logo
12:11 pm - 4:48 pmFLO-ORD
5h 37m1 stop
American Airlines Logo
9:51 am - 5:12 pmORD-FLO
6h 21m1 stop
$417American Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6
American Airlines Logo
3:30 pm - 6:29 pmFLO-ORD
3h 59m1 stop
American Airlines Logo
8:01 am - 5:12 pmORD-FLO
8h 11m2 stops
$422American Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6
American Airlines Logo
12:27 pm - 6:28 pmFLO-ORD
7h 01m2 stops
American Airlines Logo
3:33 pm - 11:16 pmORD-FLO
6h 43m2 stops
$427American Airlines
Find Deal
Thu, Sep 4 - Mon, Sep 8
American Airlines Logo
6:20 am - 12:09 pmFLO-ORD
6h 49m2 stops
American Airlines Logo
8:20 am - 5:12 pmORD-FLO
7h 52m2 stops
$458American Airlines
Find Deal
Tue, Sep 2 - Sat, Sep 6

American Airlines flights from Florence, South Carolina to Chicago O'Hare Intl Airport

Our best American Airlines deals on Florence, South Carolina to Chicago O'Hare Intl Airport flight tickets
American Airlines
Sep 2
FLO12:11 pmFlorence
5h 37m
1 stop
ORD4:48 pmChicago O'Hare Intl
Sep 6
ORD9:51 amChicago O'Hare Intl
6h 21m
1 stop
FLO5:12 pmFlorence
$417
Find similar
American Airlines
Sep 2
FLO3:30 pmFlorence
3h 59m
1 stop
ORD6:29 pmChicago O'Hare Intl
Sep 6
ORD8:01 amChicago O'Hare Intl
8h 11m
2 stops
FLO5:12 pmFlorence
$422
Find similar
American Airlines
Sep 4
FLO12:27 pmFlorence
7h 01m
2 stops
ORD6:28 pmChicago O'Hare Intl
Sep 8
ORD3:33 pmChicago O'Hare Intl
6h 43m
2 stops
FLO11:16 pmFlorence
$427
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Florence, South Carolina to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Florence, South Carolina to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

FlorenceChicago

FLO - ORD

FLOORD

Florence

Tue 9/2

12:11 pm-4:48 pm

1 stop5h 37m

Chicago O'Hare Intl

Sat 9/6

9:51 am-5:12 pm

1 stop6h 21m

$417

FlorenceChicago

FLO - ORD

FLOORD

Florence

Tue 9/2

3:30 pm-6:29 pm

1 stop3h 59m

Chicago O'Hare Intl

Sat 9/6

8:01 am-5:12 pm

2 stops8h 11m

$422

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 9/4

12:27 pm-6:28 pm

2 stops7h 01m

Chicago O'Hare Intl

Mon 9/8

3:33 pm-11:16 pm

2 stops6h 43m

$427

FlorenceChicago

FLO - ORD

FLOORD

Florence

Tue 9/2

6:20 am-12:09 pm

2 stops6h 49m

Chicago O'Hare Intl

Sat 9/6

8:20 am-5:12 pm

2 stops7h 52m

$458

FlorenceChicago

FLO - ORD

FLOORD

Florence

Sun 9/7

5:14 am-10:47 am

1 stop6h 33m

$209

FlorenceChicago

FLO - ORD

FLOORD

Florence

Sun 9/7

5:14 am-12:02 pm

2 stops7h 48m

$214

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Chicago from

How to get the cheapest flight ticket from Florence, South Carolina to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Florence, South Carolina to Chicago O'Hare Intl Airport flights?

You could potentially save up to 15% on your flight if you consider stops on a Florence, South Carolina to Chicago O'Hare Intl Airport flight.

When to book flights from Florence, South Carolina to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Florence, South Carolina to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Florence, South Carolina to Chicago O'Hare Intl Airport (FLO to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Florence, South Carolina to Chicago O'Hare Intl Airport

Direct flights

None
There are no direct flights from Florence, South Carolina to Chicago O'Hare Intl Airport. There are no popular flight routes from Florence, South Carolina to Chicago O'Hare Intl Airport.
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  • How far is Florence to Chicago O'Hare Intl by plane?

    A flight from Florence to Chicago O'Hare Intl will travel around 695.4 mi. Typically, this will take 3h 59m by plane in normal conditions.

  • When did momondo last update prices for flights from Florence Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Florence Airport to Chicago O'Hare Intl Airport refresh daily.

  • How many operators does momondo search for flights from Florence Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Florence Airport to Chicago O'Hare Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Florence Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The necessary travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Florence, South Carolina to Chicago O'Hare Intl Airport?

Best airlines flying from Florence, South Carolina to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Florence, South Carolina to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $176Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

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Why use momondo?

Why should I use momondo to find a flight deal from Florence to Chicago?

Finding the right flight to Chicago from Florence is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Chicago quick and easy, saving you time and money.

Can I find flights from Florence to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Florence which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Florence to Chicago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Chicago from Florence.

I’m not ready to book a flight from Florence to Chicago right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Chicago from Florence. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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