What airlines fly to Spain?

American Airlines, Iberia and United Airlines are the top three most popular airlines that fly to Spain from Des Moines according to our data. American Airlines is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Spain. Keep in mind that there are 6 different airlines that fly to Spain on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to Spain?

Air Canada, British Airways, and Delta are the most popular carriers operating from Des Moines to Spain

When did momondo last update prices for flights from Des Moines Airport to Spain?

Prices for flights from Des Moines Airport to Spain refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Spain?

The number of operators available for flights from Des Moines Airport to Spain is 6 as of November 2026.

How old do you have to be to fly from Des Moines Airport to Spain?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Spain.

What documentation or ID do you need to fly to Spain?

The necessary travel and health documents for your Spain trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$364 Cheap Flights from Des Moines to Spain in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Spain

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:18 pm - 8:00 amDSM Des Moines-MAD Madrid Barajas

30h 42m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl

1:25 pm - 6:43 pmMAD Madrid Barajas-DSM Des Moines

36h 18m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$717Air Canada

Sun, Feb 14 - Thu, Feb 18

7:38 am - 8:00 amDSM Des Moines-MAD Madrid Barajas

41h 22m2 stops Chicago O'Hare Intl Montreal Pierre Elliott Trudeau Intl

1:25 pm - 6:43 pmMAD Madrid Barajas-DSM Des Moines

36h 18m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$717Air Canada

Sun, Feb 14 - Thu, Feb 18

9:00 am - 9:30 amDSM Des Moines-MAD Madrid Barajas

17h 30m2 stops Denver Intl Newark

1:25 pm - 12:12 pmMAD Madrid Barajas-DSM Des Moines

29h 47m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$718United Airlines

Mon, Mar 1 - Wed, Mar 3

3:05 pm - 4:50 pmDSM Des Moines-BCN Barcelona-El Prat

18h 45m2 stops Chicago O'Hare Intl Brussels Bruxelles-National

1:35 pm - 2:12 pmBCN Barcelona-El Prat-DSM Des Moines

31h 37m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$730United Airlines

Mon, Mar 1 - Thu, Mar 4

7:25 am - 3:20 pmDSM Des Moines-MAD Madrid Barajas

24h 55m2 stops New York LaGuardia Paris Charles de Gaulle

9:20 am - 8:00 pmMAD Madrid Barajas-DSM Des Moines

16h 40m1 stop New York John F Kennedy Intl

$738Delta

Tue, Mar 9 - Tue, Mar 16

7:25 am - 9:10 amDSM Des Moines-MAD Madrid Barajas

18h 45m2 stops New York LaGuardia Paris Charles de Gaulle

9:20 am - 8:00 pmMAD Madrid Barajas-DSM Des Moines

16h 40m1 stop New York John F Kennedy Intl

$738Delta

Wed, Mar 10 - Tue, Mar 16

8:56 am - 6:45 amDSM Des Moines-BCN Barcelona-El Prat

14h 49m1 stop Chicago O'Hare Intl

10:30 am - 6:36 pmBCN Barcelona-El Prat-DSM Des Moines

15h 06m1 stop Chicago O'Hare Intl

$744Iberia

Mon, May 3 - Thu, May 6

7:18 am - 8:55 amDSM Des Moines-MAD Madrid Barajas

18h 37m1 stop Chicago O'Hare Intl

12:55 am - 3:21 pmMAD Madrid Barajas-DSM Des Moines

20h 26m1 stop Dallas/Fort Worth

$749American Airlines

Wed, Mar 10 - Wed, Mar 17

2:05 pm - 8:50 amDSM Des Moines-MAD Madrid Barajas

11h 45m1 stop Chicago O'Hare Intl

12:55 pm - 10:43 pmMAD Madrid Barajas-DSM Des Moines

16h 48m2 stops London Heathrow Chicago O'Hare Intl

$783Iberia

Sun, Dec 6 - Tue, Dec 22

10:46 am - 6:10 amDSM Des Moines-MAD Madrid Barajas

12h 24m1 stop Dallas/Fort Worth

12:40 pm - 11:58 pmMAD Madrid Barajas-DSM Des Moines

18h 18m1 stop Charlotte Douglas

$784American Airlines

Sun, Feb 14 - Sun, Feb 21

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Lufthansa flights from Des Moines to Spain

Our best Lufthansa deals on Des Moines to Spain flight tickets

Lufthansa

Jan 19

DSM12:52 pmDes Moines

21h 58m

2 stops

MAD5:50 pmMadrid Barajas

Feb 2

MAD6:05 amMadrid Barajas

22h 18m

2 stops

DSM9:23 pmDes Moines

$752

Lufthansa

Dec 9

DSM3:20 pmDes Moines

19h 30m

2 stops

MAD5:50 pmMadrid Barajas

Dec 23

MAD6:05 amMadrid Barajas

46h 18m

2 stops

DSM9:23 pmDes Moines

$768

Lufthansa

Mar 9

DSM6:15 amDes Moines

19h 05m

1 stop

BCN8:20 amBarcelona-El Prat

Mar 18

BCN6:50 amBarcelona-El Prat

20h 45m

2 stops

DSM9:35 pmDes Moines

$796

Air Canada flights from Des Moines to Spain

Our best Air Canada deals on Des Moines to Spain flight tickets

Air Canada

Feb 14

DSM7:38 amDes Moines

41h 22m

2 stops

MAD8:00 amMadrid Barajas

Feb 18

MAD1:25 pmMadrid Barajas

36h 18m

2 stops

DSM6:43 pmDes Moines

$717

Air Canada

Nov 24

DSM9:50 amDes Moines

16h 45m

2 stops

BCN9:35 amBarcelona-El Prat

Dec 11

BCN1:35 pmBarcelona-El Prat

30h 04m

2 stops

DSM12:39 pmDes Moines

$798

Air Canada

Nov 16

DSM6:45 pmDes Moines

30h 15m

2 stops

MAD8:00 amMadrid Barajas

Nov 24

MAD1:25 pmMadrid Barajas

35h 03m

2 stops

DSM5:28 pmDes Moines

$802

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Sun 2/14

6:18 pm-8:00 am

2 stops30h 42m

Madrid Barajas

Thu 2/18

1:25 pm-6:43 pm

2 stops36h 18m

$717

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Sun 2/14

7:38 am-8:00 am

2 stops41h 22m

Madrid Barajas

Thu 2/18

1:25 pm-6:43 pm

2 stops36h 18m

$717

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Mon 3/1

9:00 am-9:30 am

2 stops17h 30m

Madrid Barajas

Wed 3/3

1:25 pm-12:12 pm

2 stops29h 47m

$718

Des MoinesBarcelona

DSM Des Moines - BCN Barcelona-El Prat

DSMBCN

Des Moines

Mon 3/1

3:05 pm-4:50 pm

2 stops18h 45m

Barcelona-El Prat

Thu 3/4

1:35 pm-2:12 pm

2 stops31h 37m

$730

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Tue 3/9

7:25 am-3:20 pm

2 stops24h 55m

Madrid Barajas

Tue 3/16

9:20 am-8:00 pm

1 stop16h 40m

$738

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Wed 3/10

7:25 am-9:10 am

2 stops18h 45m

Madrid Barajas

Tue 3/16

9:20 am-8:00 pm

1 stop16h 40m

$738

Des MoinesBarcelona

DSM Des Moines - BCN Barcelona-El Prat

DSMBCN

Des Moines

Mon 5/3

8:56 am-6:45 am

1 stop14h 49m

Barcelona-El Prat

Thu 5/6

10:30 am-6:36 pm

1 stop15h 06m

$744

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Wed 3/10

7:18 am-8:55 am

1 stop18h 37m

Madrid Barajas

Wed 3/17

12:55 am-3:21 pm

1 stop20h 26m

$749

Quickest round-trip

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Sun 12/6

2:05 pm-8:50 am

1 stop11h 45m

Madrid Barajas

Tue 12/22

12:55 pm-10:43 pm

2 stops16h 48m

$783

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Sun 2/14

10:46 am-6:10 am

1 stop12h 24m

Madrid Barajas

Sun 2/21

12:40 pm-11:58 pm

1 stop18h 18m

$784

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Spain

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Spain?

If you don’t want to visit Spain in February, then you should wait until April to fly from Des Moines, when ticket prices are also cheap, with an average price of $731.

Can stopping save me money on Des Moines to Spain flights?

You could potentially save up to 10% on your flight if you consider stops on a Des Moines to Spain flight.

Cheap Des Moines to Spain flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Spain

Best Price Found	$364
Fastest flight time	14h 49m
Direct flights	None

The best one-way flight to Spain from Des Moines in the past 72 hours is $364. The best round-trip flight deal from Des Moines to Spain found on momondo in the last 72 hours is $717.

The fastest flight from Des Moines to Spain takes 14h 49m

There are no direct flights from Des Moines to Spain. There are no popular flight routes from Des Moines to Spain.

Search flight deals

Frequently asked questions about flying from Des Moines to Spain

When did momondo last update prices for flights from Des Moines Airport to Spain?
Prices for flights from Des Moines Airport to Spain refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Spain?
The number of operators available for flights from Des Moines Airport to Spain is 6 as of November 2026.
How old do you have to be to fly from Des Moines Airport to Spain?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Spain.
What documentation or ID do you need to fly to Spain?
The necessary travel and health documents for your Spain trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Spain

Compare and see reviews for airlines that fly from Des Moines to Spain with momondo

Airline	Rating	Free Cancellation	Price
British Airways	PriceFrom $484	Free Cancellation	Rating 6.7 8,283 reviews	Search British Airways flights
United Airlines	PriceFrom $484	Free Cancellation	Rating 7.3 10,487 reviews	Search United Airlines flights
American Airlines	PriceFrom $486	Free Cancellation	Rating 7.0 12,235 reviews	Search American Airlines flights
Delta	PriceFrom $488	Free Cancellation	Rating 7.8 8,722 reviews	Search Delta flights
Iberia	PriceFrom $575	Free Cancellation	Rating 7.0 3,228 reviews	Search Iberia flights
Lufthansa	PriceFrom $716	Free Cancellation	Rating 6.8 8,294 reviews	Search Lufthansa flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Spain?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Spain for you.

Can I find flights from Des Moines to Spain with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Spain flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Spain?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Spain from Des Moines.

I’m not ready to book a flight from Des Moines to Spain right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Spain flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.