What airlines fly to Spain?

American Airlines, United Airlines and Iberia are the top three most popular airlines that fly to Spain from Des Moines according to our data. American Airlines is the first choice among our users, with 45% of people opting to fly with this airline when traveling to Spain. Keep in mind that there are 5 different airlines that fly to Spain on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Des Moines to Spain?

British Airways, United Airlines, and Iberia are the most popular carriers operating from Des Moines to Spain

When did momondo last update prices for flights from Des Moines Airport to Spain?

Prices for flights from Des Moines Airport to Spain refresh daily.

How many operators does momondo search for flights from Des Moines Airport to Spain?

The number of operators available for flights from Des Moines Airport to Spain is 5 as of August 2026.

How old do you have to be to fly from Des Moines Airport to Spain?

The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Spain.

What documentation or ID do you need to fly to Spain?

The necessary travel and health documents for your Spain trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$315 Cheap Flights from Des Moines to Spain in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Spain

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:45 pm - 5:50 pmDSM Des Moines-MAD Madrid Barajas

16h 05m2 stops Chicago O'Hare Intl Munich Franz Josef Strauss

6:05 am - 9:17 pmMAD Madrid Barajas-DSM Des Moines

22h 12m2 stops Frankfurt am Main Chicago O'Hare Intl

$706Lufthansa

Mon, Jan 4 - Thu, Jan 14

3:22 pm - 7:50 pmDSM Des Moines-MAD Madrid Barajas

21h 28m2 stops Chicago O'Hare Intl Frankfurt am Main

5:55 am - 5:48 pmMAD Madrid Barajas-DSM Des Moines

18h 53m2 stops Frankfurt am Main Chicago O'Hare Intl

$708Lufthansa

Tue, Sep 22 - Tue, Sep 29

6:05 am - 9:15 amDSM Des Moines-MAD Madrid Barajas

20h 10m2 stops Chicago O'Hare Intl Newark

1:25 pm - 5:23 pmMAD Madrid Barajas-DSM Des Moines

34h 58m2 stops Montreal Pierre Elliott Trudeau Intl Chicago O'Hare Intl

$710United Airlines

Mon, Nov 2 - Tue, Nov 10

5:45 am - 10:55 amDSM Des Moines-MAD Madrid Barajas

22h 10m1 stop Atlanta Hartsfield-Jackson

12:55 pm - 10:29 pmMAD Madrid Barajas-DSM Des Moines

16h 34m1 stop Atlanta Hartsfield-Jackson

$720Delta

Mon, Jan 4 - Thu, Jan 14

2:29 pm - 1:30 pmDSM Des Moines-MAD Madrid Barajas

16h 01m1 stop Chicago O'Hare Intl

3:25 pm - 9:36 pmMAD Madrid Barajas-DSM Des Moines

13h 11m1 stop Philadelphia

$723American Airlines

Wed, Sep 23 - Wed, Sep 30

6:22 pm - 2:25 pmDSM Des Moines-MAD Madrid Barajas

13h 03m1 stop Dallas/Fort Worth

3:25 pm - 9:36 pmMAD Madrid Barajas-DSM Des Moines

13h 11m1 stop Philadelphia

$723American Airlines

Tue, Sep 22 - Tue, Sep 29

5:35 pm - 3:35 pmDSM Des Moines-MAD Madrid Barajas

15h 00m2 stops Detroit Metropolitan Wayne County Paris Charles de Gaulle

9:50 am - 10:33 pmMAD Madrid Barajas-DSM Des Moines

19h 43m1 stop Atlanta Hartsfield-Jackson

$735Delta

Mon, Oct 5 - Wed, Oct 21

2:29 pm - 1:30 pmDSM Des Moines-MAD Madrid Barajas

16h 01m1 stop Chicago O'Hare Intl

9:00 pm - 7:21 pmMAD Madrid Barajas-DSM Des Moines

29h 21m2 stops London Heathrow Chicago O'Hare Intl

$743Iberia

Mon, Sep 21 - Mon, Sep 28

5:56 pm - 1:30 pmDSM Des Moines-MAD Madrid Barajas

12h 34m1 stop Chicago O'Hare Intl

10:35 am - 12:04 amMAD Madrid Barajas-DSM Des Moines

20h 29m2 stops London Heathrow Chicago O'Hare Intl

$743Iberia

Wed, Sep 23 - Wed, Sep 30

8:00 am - 8:20 amDSM Des Moines-BCN Barcelona-El Prat

17h 20m3 stops Chicago O'Hare Intl Washington, D.C. Reagan-National Newark

11:00 am - 9:17 pmBCN Barcelona-El Prat-DSM Des Moines

17h 17m2 stops Newark Chicago O'Hare Intl

$774United Airlines

Sun, Jan 31 - Thu, Feb 4

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Air Canada flights from Des Moines to Spain

Our best Air Canada deals on Des Moines to Spain flight tickets

Air Canada

Oct 5

DSM6:55 pmDes Moines

28h 55m

2 stops

MAD6:50 amMadrid Barajas

Oct 21

MAD1:30 pmMadrid Barajas

38h 53m

2 stops

DSM9:23 pmDes Moines

$719

Air Canada

Jan 31

DSM8:00 amDes Moines

18h 35m

2 stops

BCN9:35 amBarcelona-El Prat

Feb 4

BCN1:35 pmBarcelona-El Prat

40h 26m

2 stops

DSM11:01 pmDes Moines

$752

Air Canada

Nov 30

DSM6:05 amDes Moines

42h 55m

2 stops

MAD8:00 amMadrid Barajas

Dec 6

MAD1:25 pmMadrid Barajas

38h 52m

2 stops

DSM9:17 pmDes Moines

$758

Delta flights from Des Moines to Spain

Our best Delta deals on Des Moines to Spain flight tickets

Delta

Oct 5

DSM5:35 pmDes Moines

15h 00m

2 stops

MAD3:35 pmMadrid Barajas

Oct 21

MAD9:50 amMadrid Barajas

19h 43m

1 stop

DSM10:33 pmDes Moines

$735

Delta

Sep 23

DSM5:35 pmDes Moines

15h 00m

2 stops

MAD3:35 pmMadrid Barajas

Sep 30

MAD6:00 amMadrid Barajas

17h 48m

2 stops

DSM4:48 pmDes Moines

$736

Delta

Nov 29

DSM2:58 pmDes Moines

11h 57m

1 stop

MAD9:55 amMadrid Barajas

Dec 7

MAD11:55 amMadrid Barajas

17h 39m

1 stop

DSM10:34 pmDes Moines

$770

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Mon 1/4

6:45 pm-5:50 pm

2 stops16h 05m

Madrid Barajas

Thu 1/14

6:05 am-9:17 pm

2 stops22h 12m

$706

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Tue 9/22

3:22 pm-7:50 pm

2 stops21h 28m

Madrid Barajas

Tue 9/29

5:55 am-5:48 pm

2 stops18h 53m

$708

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Mon 11/2

6:05 am-9:15 am

2 stops20h 10m

Madrid Barajas

Tue 11/10

1:25 pm-5:23 pm

2 stops34h 58m

$710

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Mon 1/4

5:45 am-10:55 am

1 stop22h 10m

Madrid Barajas

Thu 1/14

12:55 pm-10:29 pm

1 stop16h 34m

$720

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Wed 9/23

2:29 pm-1:30 pm

1 stop16h 01m

Madrid Barajas

Wed 9/30

3:25 pm-9:36 pm

1 stop13h 11m

$723

Quickest round-trip

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Tue 9/22

6:22 pm-2:25 pm

1 stop13h 03m

Madrid Barajas

Tue 9/29

3:25 pm-9:36 pm

1 stop13h 11m

$723

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Mon 10/5

5:35 pm-3:35 pm

2 stops15h 00m

Madrid Barajas

Wed 10/21

9:50 am-10:33 pm

1 stop19h 43m

$735

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Mon 9/21

2:29 pm-1:30 pm

1 stop16h 01m

Madrid Barajas

Mon 9/28

9:00 pm-7:21 pm

2 stops29h 21m

$743

Des MoinesMadrid

DSM Des Moines - MAD Madrid Barajas

DSMMAD

Des Moines

Wed 9/23

5:56 pm-1:30 pm

1 stop12h 34m

Madrid Barajas

Wed 9/30

10:35 am-12:04 am

2 stops20h 29m

$743

Des MoinesBarcelona

DSM Des Moines - BCN Barcelona-El Prat

DSMBCN

Des Moines

Sun 1/31

8:00 am-8:20 am

3 stops17h 20m

Barcelona-El Prat

Thu 2/4

11:00 am-9:17 pm

2 stops17h 17m

$774

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Spain

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Spain?

If you don’t want to visit Spain in February, then you should wait until November to fly from Des Moines, when ticket prices are also cheap, with an average price of $694.

Can stopping save me money on Des Moines to Spain flights?

You could potentially save up to 25% on your flight if you consider stops on a Des Moines to Spain flight.

Cheap Des Moines to Spain flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Spain

Fastest flight time	11h 25m
Direct flights	None

The fastest flight from Des Moines to Spain takes 11h 25m

There are no direct flights from Des Moines to Spain. There are no popular flight routes from Des Moines to Spain.

Search flight deals

Frequently asked questions about flying from Des Moines to Spain

When did momondo last update prices for flights from Des Moines Airport to Spain?
Prices for flights from Des Moines Airport to Spain refresh daily.
How many operators does momondo search for flights from Des Moines Airport to Spain?
The number of operators available for flights from Des Moines Airport to Spain is 5 as of August 2026.
How old do you have to be to fly from Des Moines Airport to Spain?
The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Des Moines Airport to Spain.
What documentation or ID do you need to fly to Spain?
The necessary travel and health documents for your Spain trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Des Moines to Spain

Compare and see reviews for airlines that fly from Des Moines to Spain with momondo

Airline	Rating	Free Cancellation	Price
United Airlines	PriceFrom $483	Free Cancellation	Rating 7.4 10,103 reviews	Search United Airlines flights
British Airways	PriceFrom $484	Free Cancellation	Rating 6.7 8,157 reviews	Search British Airways flights
American Airlines	PriceFrom $486	Free Cancellation	Rating 7.1 11,902 reviews	Search American Airlines flights
Iberia	PriceFrom $488	Free Cancellation	Rating 7.0 3,263 reviews	Search Iberia flights
Delta	PriceFrom $488	Free Cancellation	Rating 7.8 8,505 reviews	Search Delta flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Spain?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Spain for you.

Can I find flights from Des Moines to Spain with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Des Moines to Spain flights to just show those with flexible booking policies.

How can momondo help me find flights from Des Moines to Spain?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Spain from Des Moines.

I’m not ready to book a flight from Des Moines to Spain right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Des Moines to Spain flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.