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Cheap flights from Des Moines to Sao Paulo from $972

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Sao Paulo departing on 1/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

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Multiple Airlines Logo
2:58 pm - 5:40 am
DSM
-
GRU
35h 42m3 stops
Multiple Airlines Logo
5:25 am - 10:46 pm
GRU
-
DSM
20h 21m2 stops
$972Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
11:26 am - 5:40 am
DSM
-
GRU
15h 14m1 stop
Multiple Airlines Logo
5:25 am - 10:46 pm
GRU
-
DSM
20h 21m2 stops
$1,080Multiple Airlines
Thu, Jan 22 - Thu, Jan 29
Multiple Airlines Logo
2:58 pm - 5:40 am
DSM
-
GRU
35h 42m3 stops
Multiple Airlines Logo
1:30 am - 10:46 pm
GRU
-
DSM
24h 16m3 stops
$1,180Multiple Airlines
Thu, Jan 22 - Wed, Jan 28
LATAM Airlines Logo
11:28 am - 5:40 am
DSM
-
GRU
15h 12m1 stop
LATAM Airlines Logo
10:55 pm - 10:38 pm
GRU
-
DSM
25h 43m2 stops
$1,197LATAM Airlines
Mon, Mar 2 - Tue, Mar 10
American Airlines Logo
6:00 am - 8:05 am
DSM
-
GRU
23h 05m1 stop
American Airlines Logo
11:00 pm - 6:58 pm
GRU
-
DSM
21h 58m1 stop
$1,200American Airlines
Mon, Mar 2 - Tue, Mar 10
American Airlines Logo
10:09 am - 8:05 am
DSM
-
GRU
18h 56m2 stops
American Airlines Logo
10:35 pm - 1:32 pm
GRU
-
DSM
16h 57m2 stops
$1,205American Airlines
Mon, Mar 2 - Tue, Mar 10
United Airlines Logo
6:55 pm - 7:15 am
DSM
-
GRU
33h 20m1 stop
United Airlines Logo
9:45 pm - 4:07 pm
GRU
-
DSM
20h 22m2 stops
$1,208United Airlines
Sun, Mar 1 - Mon, Mar 9
United Airlines Logo
6:55 pm - 10:20 am
DSM
-
GRU
36h 25m2 stops
United Airlines Logo
9:45 pm - 1:23 pm
GRU
-
DSM
17h 38m2 stops
$1,221United Airlines
Sun, Mar 1 - Mon, Mar 9
Delta Logo
5:15 pm - 9:35 am
DSM
-
GRU
13h 20m1 stop
Delta Logo
10:40 am - 10:38 pm
GRU
-
DSM
13h 58m1 stop
$1,240Delta
Sun, Mar 1 - Mon, Mar 9
Delta Logo
10:57 am - 5:40 am
DSM
-
GRU
15h 43m2 stops
Delta Logo
9:00 pm - 3:45 pm
GRU
-
DSM
20h 45m2 stops
$1,245Delta
Sun, Mar 1 - Mon, Mar 9

Delta flights from Des Moines to Sao Paulo Guarulhos Intl Airport

Our best Delta deals on Des Moines to Sao Paulo Guarulhos Intl Airport flight tickets
Delta
Mar 1
DSM5:15 pmDes Moines
13h 20m
1 stop
GRU9:35 amSao Paulo Guarulhos Intl
Mar 9
GRU4:30 pmSao Paulo Guarulhos Intl
20h 09m
2 stops
DSM10:39 amDes Moines
$1,240
Find similar
Delta
Mar 1
DSM10:57 amDes Moines
15h 43m
2 stops
GRU5:40 amSao Paulo Guarulhos Intl
Mar 9
GRU9:00 pmSao Paulo Guarulhos Intl
20h 45m
2 stops
DSM3:45 pmDes Moines
$1,245
Find similar

LATAM Airlines flights from Des Moines to Sao Paulo Guarulhos Intl Airport

Our best LATAM Airlines deals on Des Moines to Sao Paulo Guarulhos Intl Airport flight tickets
LATAM Airlines
Mar 2
DSM11:28 amDes Moines
15h 12m
1 stop
GRU5:40 amSao Paulo Guarulhos Intl
Mar 10
GRU10:55 pmSao Paulo Guarulhos Intl
25h 43m
2 stops
DSM10:38 pmDes Moines
$1,197
Find similar
LATAM Airlines
Jan 22
DSM5:16 pmDes Moines
23h 39m
2 stops
GRU7:55 pmSao Paulo Guarulhos Intl
Jan 29
GRU5:45 pmSao Paulo Guarulhos Intl
19h 56m
2 stops
DSM10:41 amDes Moines
$1,272
Find similar
LATAM Airlines
Jan 22
DSM5:16 pmDes Moines
23h 39m
2 stops
GRU7:55 pmSao Paulo Guarulhos Intl
Jan 29
GRU11:45 pmSao Paulo Guarulhos Intl
13h 56m
1 stop
DSM10:41 amDes Moines
$1,273
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Sao Paulo Guarulhos Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Des Moines to Sao Paulo Guarulhos Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 1/22

2:58 pm-5:40 am

3 stops35h 42m

Sao Paulo Guarulhos Intl

Thu 1/29

5:25 am-10:46 pm

2 stops20h 21m

$972

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 1/22

11:26 am-5:40 am

1 stop15h 14m

Sao Paulo Guarulhos Intl

Thu 1/29

5:25 am-10:46 pm

2 stops20h 21m

$1,080

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 1/22

2:58 pm-5:40 am

3 stops35h 42m

Sao Paulo Guarulhos Intl

Wed 1/28

1:30 am-10:46 pm

3 stops24h 16m

$1,180

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 3/2

11:28 am-5:40 am

1 stop15h 12m

Sao Paulo Guarulhos Intl

Tue 3/10

10:55 pm-10:38 pm

2 stops25h 43m

$1,197

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 3/2

6:00 am-8:05 am

1 stop23h 05m

Sao Paulo Guarulhos Intl

Tue 3/10

11:00 pm-6:58 pm

1 stop21h 58m

$1,200

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 3/2

10:09 am-8:05 am

2 stops18h 56m

Sao Paulo Guarulhos Intl

Tue 3/10

10:35 pm-1:32 pm

2 stops16h 57m

$1,205

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 3/1

6:55 pm-7:15 am

1 stop33h 20m

Sao Paulo Guarulhos Intl

Mon 3/9

9:45 pm-4:07 pm

2 stops20h 22m

$1,208

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 3/1

6:55 pm-10:20 am

2 stops36h 25m

Sao Paulo Guarulhos Intl

Mon 3/9

9:45 pm-1:23 pm

2 stops17h 38m

$1,221

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 3/1

5:15 pm-9:35 am

1 stop13h 20m

Sao Paulo Guarulhos Intl

Mon 3/9

10:40 am-10:38 pm

1 stop13h 58m

$1,240

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 3/1

10:57 am-5:40 am

2 stops15h 43m

Sao Paulo Guarulhos Intl

Mon 3/9

9:00 pm-3:45 pm

2 stops20h 45m

$1,245

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Des Moines to Sao Paulo Guarulhos Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Sao Paulo Guarulhos Intl Airport?

On average, the least expensive day to fly to Sao Paulo Guarulhos Intl Airport from Des Moines is on a Sunday. momondo users have found tickets for Sunday departures for as low as $747. However, this price may fluctuate depending on the airline, the season, and holidays. The most expensive day to fly to Sao Paulo Guarulhos Intl Airport is Saturday, with ticket prices averaging around $1,633.

What is the cheapest time of day to depart on your flight to Sao Paulo Guarulhos Intl Airport?

Our data shows that the cheapest Des Moines to Sao Paulo Guarulhos Intl Airport flights are usually those with departure times in the afternoon. Our users have found flights to Sao Paulo Guarulhos Intl Airport in the afternoon for as low as $997. Flights in the morning are often more expensive with an average ticket price of $1,394.

When to book flights from Des Moines to Sao Paulo Guarulhos Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Sao Paulo Guarulhos Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Sao Paulo Guarulhos Intl Airport (DSM to GRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Sao Paulo Guarulhos Intl Airport

Fastest flight time

15h 31m

Direct flights

None
The fastest flight from Des Moines to Sao Paulo Guarulhos Intl Airport takes 15h 31m
There are no direct flights from Des Moines to Sao Paulo Guarulhos Intl Airport. There are no popular flight routes from Des Moines to Sao Paulo Guarulhos Intl Airport.
Search flight deals

  • How far is Des Moines to Sao Paulo Guarulhos Intl by plane?

    The distance between Des Moines and Sao Paulo Guarulhos Intl is about 5406.4 mi. A reasonable flight in good conditions will take 15h 31m.

  • When did momondo last update prices for flights from Des Moines Airport to Sao Paulo Guarulhos Intl Airport?

    Prices for flights from Des Moines Airport to Sao Paulo Guarulhos Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Des Moines Airport to Sao Paulo Guarulhos Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Sao Paulo Guarulhos Intl Airport.

  • What documentation or ID do you need to fly to Sao Paulo Guarulhos Intl Airport?

    The required travel and health documents for your Sao Paulo Guarulhos Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Sao Paulo Guarulhos Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Guarulhos
Santos
Guarujá
Campinas
Aparecida

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Sao Paulo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Sao Paulo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Sao Paulo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Sao Paulo from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Sao Paulo?

momondo helps you find the best flight between Des Moines and Sao Paulo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Sao Paulo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Sao Paulo, momondo offers a useful price alert feature which will track prices for flights to Sao Paulo from Des Moines and alert you when they change.

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