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Cheap flights from Des Moines to Sao Paulo from $388

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Sao Paulo departing on 8/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Des Moines to Sao Paulo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:15 am - 12:10 am
DSM
-
GRU
38h 55m
2 stops
Multiple Airlines Logo
3:50 am - 9:26 pm
GRU
-
DSM
19h 36m
2 stops
$907Multiple Airlines
Fri, Aug 21 - Thu, Aug 27
Multiple Airlines Logo
10:24 am - 7:50 am
DSM
-
GRU
19h 26m
1 stop
Multiple Airlines Logo
11:45 pm - 11:54 am
GRU
-
DSM
38h 09m
2 stops
$919Multiple Airlines
Mon, Sep 14 - Mon, Sep 21
LATAM Airlines Logo
6:35 pm - 5:25 am
DSM
-
GRU
32h 50m
2 stops
LATAM Airlines Logo
1:15 pm - 3:16 pm
GRU
-
DSM
28h 01m
2 stops
$999LATAM Airlines
Mon, Aug 24 - Mon, Aug 31
LATAM Airlines Logo
6:35 pm - 8:50 am
DSM
-
GRU
36h 15m
2 stops
LATAM Airlines Logo
5:45 pm - 3:16 pm
GRU
-
DSM
23h 31m
2 stops
$1,003LATAM Airlines
Mon, Aug 24 - Mon, Aug 31
Multiple Airlines Logo
8:00 am - 5:40 am
DSM
-
GRU
43h 40m
2 stops
Multiple Airlines Logo
8:30 am - 9:34 am
GRU
-
DSM
27h 04m
1 stop
$1,013Multiple Airlines
Sun, Sep 13 - Sun, Sep 20
LATAM Airlines Logo
6:54 pm - 5:30 am
DSM
-
GRU
32h 36m
2 stops
LATAM Airlines Logo
7:00 am - 10:46 am
GRU
-
DSM
29h 46m
2 stops
$1,025LATAM Airlines
Mon, Sep 14 - Mon, Sep 21
LATAM Airlines Logo
6:35 pm - 5:25 am
DSM
-
GRU
32h 50m
2 stops
LATAM Airlines Logo
12:45 pm - 3:16 pm
GRU
-
DSM
28h 31m
2 stops
$1,045LATAM Airlines
Tue, Aug 25 - Tue, Sep 1
LATAM Airlines Logo
6:35 pm - 5:00 am
DSM
-
GRU
32h 25m
2 stops
LATAM Airlines Logo
1:05 pm - 5:50 pm
GRU
-
DSM
30h 45m
2 stops
$1,046LATAM Airlines
Wed, Aug 19 - Wed, Aug 26
Multiple Airlines Logo
2:53 pm - 2:50 am
DSM
-
GRU
33h 57m
2 stops
Multiple Airlines Logo
10:50 pm - 10:43 am
GRU
-
DSM
13h 53m
1 stop
$1,058Multiple Airlines
Mon, Aug 24 - Mon, Aug 31
Multiple Airlines Logo
2:54 pm - 5:40 am
DSM
-
GRU
12h 46m
1 stop
Multiple Airlines Logo
3:50 am - 9:26 pm
GRU
-
DSM
19h 36m
2 stops
$1,191Multiple Airlines
Fri, Aug 21 - Thu, Aug 27

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American Airlines flights from Des Moines to Sao Paulo Guarulhos Intl Airport

Our best American Airlines deals on Des Moines to Sao Paulo Guarulhos Intl Airport flight tickets
American Airlines
Jan 5
DSM3:28 pmDes Moines
17h 52m
2 stops
GRU12:20 pmSao Paulo Guarulhos Intl
Jan 12
GRU10:45 pmSao Paulo Guarulhos Intl
19h 29m
1 stop
DSM3:14 pmDes Moines
$1,320
American Airlines
Sep 13
DSM2:59 pmDes Moines
16h 01m
1 stop
GRU9:00 amSao Paulo Guarulhos Intl
Sep 20
GRU10:00 pmSao Paulo Guarulhos Intl
21h 52m
1 stop
DSM5:52 pmDes Moines
$1,413
American Airlines
Aug 20
DSM1:55 pmDes Moines
17h 05m
2 stops
GRU9:00 amSao Paulo Guarulhos Intl
Aug 27
GRU9:25 pmSao Paulo Guarulhos Intl
18h 00m
2 stops
DSM1:25 pmDes Moines
$1,435

United Airlines flights from Des Moines to Sao Paulo Guarulhos Intl Airport

Our best United Airlines deals on Des Moines to Sao Paulo Guarulhos Intl Airport flight tickets
United Airlines
Jan 5
DSM3:00 pmDes Moines
15h 30m
1 stop
GRU9:30 amSao Paulo Guarulhos Intl
Jan 12
GRU9:30 pmSao Paulo Guarulhos Intl
15h 50m
1 stop
DSM10:20 amDes Moines
$1,328
United Airlines
Aug 20
DSM3:20 pmDes Moines
16h 20m
1 stop
GRU9:40 amSao Paulo Guarulhos Intl
Aug 27
GRU9:50 pmSao Paulo Guarulhos Intl
18h 24m
1 stop
DSM2:14 pmDes Moines
$1,443

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Sao Paulo Guarulhos Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 11, 2026.
Use the filters below to find and compare flights from Des Moines to Sao Paulo Guarulhos Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Fri 8/21

7:15 am-12:10 am

2 stops38h 55m

Sao Paulo Guarulhos Intl

Thu 8/27

3:50 am-9:26 pm

2 stops19h 36m

$907

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 9/14

10:24 am-7:50 am

1 stop19h 26m

Sao Paulo Guarulhos Intl

Mon 9/21

11:45 pm-11:54 am

2 stops38h 09m

$919

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 8/24

6:35 pm-5:25 am

2 stops32h 50m

Sao Paulo Guarulhos Intl

Mon 8/31

1:15 pm-3:16 pm

2 stops28h 01m

$999

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 8/24

6:35 pm-8:50 am

2 stops36h 15m

Sao Paulo Guarulhos Intl

Mon 8/31

5:45 pm-3:16 pm

2 stops23h 31m

$1,003

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 9/13

8:00 am-5:40 am

2 stops43h 40m

Sao Paulo Guarulhos Intl

Sun 9/20

8:30 am-9:34 am

1 stop27h 04m

$1,013

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 9/14

6:54 pm-5:30 am

2 stops32h 36m

Sao Paulo Guarulhos Intl

Mon 9/21

7:00 am-10:46 am

2 stops29h 46m

$1,025

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 8/25

6:35 pm-5:25 am

2 stops32h 50m

Sao Paulo Guarulhos Intl

Tue 9/1

12:45 pm-3:16 pm

2 stops28h 31m

$1,045

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 8/19

6:35 pm-5:00 am

2 stops32h 25m

Sao Paulo Guarulhos Intl

Wed 8/26

1:05 pm-5:50 pm

2 stops30h 45m

$1,046

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 8/24

2:53 pm-2:50 am

2 stops33h 57m

Sao Paulo Guarulhos Intl

Mon 8/31

10:50 pm-10:43 am

1 stop13h 53m

$1,058
Quickest round-trip

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Fri 8/21

2:54 pm-5:40 am

1 stop12h 46m

Sao Paulo Guarulhos Intl

Thu 8/27

3:50 am-9:26 pm

2 stops19h 36m

$1,191

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Des Moines to Sao Paulo Guarulhos Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Sao Paulo Guarulhos Intl?

Air Canada and LATAM Airlines are the most popular carriers operating from Des Moines to Sao Paulo Guarulhos Intl

When to book flights from Des Moines to Sao Paulo Guarulhos Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Sao Paulo Guarulhos Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Sao Paulo Guarulhos Intl Airport (DSM to GRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Sao Paulo Guarulhos Intl Airport

Fastest flight time

19h 26m

Direct flights

None
The fastest flight from Des Moines to Sao Paulo Guarulhos Intl Airport takes 19h 26m
There are no direct flights from Des Moines to Sao Paulo Guarulhos Intl Airport. There are no popular flight routes from Des Moines to Sao Paulo Guarulhos Intl Airport.
Search flight deals

Frequently asked questions about flying from Des Moines to Sao Paulo Guarulhos Intl Airport

  • How far is Des Moines to Sao Paulo Guarulhos Intl by plane?

    The distance between Des Moines and Sao Paulo Guarulhos Intl is about 5406.4 mi. A reasonable flight in good conditions will take 19h 26m.

  • When did momondo last update prices for flights from Des Moines Airport to Sao Paulo Guarulhos Intl Airport?

    Prices for flights from Des Moines Airport to Sao Paulo Guarulhos Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Des Moines Airport to Sao Paulo Guarulhos Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Sao Paulo Guarulhos Intl Airport.

  • What documentation or ID do you need to fly to Sao Paulo Guarulhos Intl Airport?

    The required travel and health documents for your Sao Paulo Guarulhos Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Sao Paulo Guarulhos Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Guarulhos
Santos
Guarujá
Campinas
Aparecida

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Sao Paulo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Sao Paulo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Sao Paulo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Sao Paulo from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Sao Paulo?

momondo helps you find the best flight between Des Moines and Sao Paulo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Sao Paulo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Sao Paulo, momondo offers a useful price alert feature which will track prices for flights to Sao Paulo from Des Moines and alert you when they change.

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