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Cheap flights from Des Moines to Sao Paulo from $311

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Sao Paulo departing on 3/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:26 pm - 8:10 am
DSM
-
GRU
14h 44m
1 stop
American Airlines Logo
11:00 pm - 2:56 pm
GRU
-
DSM
17h 56m
1 stop
$1,270American Airlines
Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
11:17 am - 8:05 am
DSM
-
GRU
18h 48m
2 stops
American Airlines Logo
12:15 am - 6:19 pm
GRU
-
DSM
20h 04m
2 stops
$1,271American Airlines
Wed, Mar 18 - Tue, Mar 24
American Airlines Logo
1:37 pm - 8:05 am
DSM
-
GRU
16h 28m
2 stops
American Airlines Logo
12:15 am - 5:38 pm
GRU
-
DSM
19h 23m
2 stops
$1,275American Airlines
Tue, Mar 17 - Mon, Mar 23
American Airlines Logo
11:17 am - 6:20 am
DSM
-
GRU
17h 03m
2 stops
American Airlines Logo
10:35 pm - 1:18 pm
GRU
-
DSM
16h 43m
2 stops
$1,278American Airlines
Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
7:00 am - 8:05 am
DSM
-
GRU
23h 05m
1 stop
American Airlines Logo
11:30 pm - 2:56 pm
GRU
-
DSM
17h 26m
2 stops
$1,280American Airlines
Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
11:17 am - 8:10 am
DSM
-
GRU
18h 53m
1 stop
American Airlines Logo
10:35 pm - 11:56 pm
GRU
-
DSM
27h 21m
1 stop
$1,289American Airlines
Tue, Mar 17 - Tue, Mar 24
American Airlines Logo
3:26 pm - 8:10 am
DSM
-
GRU
14h 44m
1 stop
American Airlines Logo
12:15 am - 5:38 pm
GRU
-
DSM
19h 23m
2 stops
$1,293American Airlines
Tue, Mar 17 - Mon, Mar 23
LATAM Airlines Logo
5:20 pm - 9:35 am
DSM
-
GRU
14h 15m
1 stop
LATAM Airlines Logo
10:40 am - 10:48 am
GRU
-
DSM
26h 08m
1 stop
$1,297LATAM Airlines
Mon, Mar 16 - Mon, Mar 23
American Airlines Logo
7:00 am - 8:50 am
DSM
-
GRU
23h 50m
1 stop
American Airlines Logo
11:00 pm - 11:42 pm
GRU
-
DSM
26h 42m
1 stop
$1,298American Airlines
Wed, Mar 18 - Wed, Mar 25
American Airlines Logo
11:17 am - 6:20 am
DSM
-
GRU
17h 03m
2 stops
American Airlines Logo
10:35 pm - 2:56 pm
GRU
-
DSM
18h 21m
2 stops
$1,303American Airlines
Wed, Mar 18 - Wed, Mar 25

American Airlines flights from Des Moines to Sao Paulo Guarulhos Intl Airport

Our best American Airlines deals on Des Moines to Sao Paulo Guarulhos Intl Airport flight tickets
American Airlines
Mar 18
DSM3:26 pmDes Moines
14h 44m
1 stop
GRU8:10 amSao Paulo Guarulhos Intl
Mar 25
GRU11:00 pmSao Paulo Guarulhos Intl
17h 56m
1 stop
DSM2:56 pmDes Moines
$1,270
American Airlines
Mar 18
DSM11:17 amDes Moines
18h 48m
2 stops
GRU8:05 amSao Paulo Guarulhos Intl
Mar 24
GRU12:15 amSao Paulo Guarulhos Intl
20h 04m
2 stops
DSM6:19 pmDes Moines
$1,271
American Airlines
Mar 17
DSM1:37 pmDes Moines
16h 28m
2 stops
GRU8:05 amSao Paulo Guarulhos Intl
Mar 23
GRU12:15 amSao Paulo Guarulhos Intl
19h 23m
2 stops
DSM5:38 pmDes Moines
$1,275

United Airlines flights from Des Moines to Sao Paulo Guarulhos Intl Airport

Our best United Airlines deals on Des Moines to Sao Paulo Guarulhos Intl Airport flight tickets
United Airlines
Mar 18
DSM2:04 pmDes Moines
17h 26m
2 stops
GRU9:30 amSao Paulo Guarulhos Intl
Mar 25
GRU10:15 pmSao Paulo Guarulhos Intl
17h 08m
1 stop
DSM1:23 pmDes Moines
$1,293
United Airlines
Mar 18
DSM2:04 pmDes Moines
16h 51m
2 stops
GRU8:55 amSao Paulo Guarulhos Intl
Mar 25
GRU10:25 pmSao Paulo Guarulhos Intl
17h 59m
2 stops
DSM2:24 pmDes Moines
$1,297
United Airlines
Mar 1
DSM3:24 pmDes Moines
15h 56m
2 stops
GRU10:20 amSao Paulo Guarulhos Intl
Mar 9
GRU10:25 pmSao Paulo Guarulhos Intl
16h 58m
2 stops
DSM1:23 pmDes Moines
$1,407

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Sao Paulo Guarulhos Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 2, 2026.
Use the filters below to find and compare flights from Des Moines to Sao Paulo Guarulhos Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 3/18

3:26 pm-8:10 am

1 stop14h 44m

Sao Paulo Guarulhos Intl

Wed 3/25

11:00 pm-2:56 pm

1 stop17h 56m

$1,270

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 3/18

11:17 am-8:05 am

2 stops18h 48m

Sao Paulo Guarulhos Intl

Tue 3/24

12:15 am-6:19 pm

2 stops20h 04m

$1,271

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 3/17

1:37 pm-8:05 am

2 stops16h 28m

Sao Paulo Guarulhos Intl

Mon 3/23

12:15 am-5:38 pm

2 stops19h 23m

$1,275

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 3/18

11:17 am-6:20 am

2 stops17h 03m

Sao Paulo Guarulhos Intl

Wed 3/25

10:35 pm-1:18 pm

2 stops16h 43m

$1,278

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 3/18

7:00 am-8:05 am

1 stop23h 05m

Sao Paulo Guarulhos Intl

Wed 3/25

11:30 pm-2:56 pm

2 stops17h 26m

$1,280

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 3/17

11:17 am-8:10 am

1 stop18h 53m

Sao Paulo Guarulhos Intl

Tue 3/24

10:35 pm-11:56 pm

1 stop27h 21m

$1,289

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Tue 3/17

3:26 pm-8:10 am

1 stop14h 44m

Sao Paulo Guarulhos Intl

Mon 3/23

12:15 am-5:38 pm

2 stops19h 23m

$1,293

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Mon 3/16

5:20 pm-9:35 am

1 stop14h 15m

Sao Paulo Guarulhos Intl

Mon 3/23

10:40 am-10:48 am

1 stop26h 08m

$1,297

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 3/18

7:00 am-8:50 am

1 stop23h 50m

Sao Paulo Guarulhos Intl

Wed 3/25

11:00 pm-11:42 pm

1 stop26h 42m

$1,298

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Wed 3/18

11:17 am-6:20 am

2 stops17h 03m

Sao Paulo Guarulhos Intl

Wed 3/25

10:35 pm-2:56 pm

2 stops18h 21m

$1,303

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

When to book flights from Des Moines to Sao Paulo Guarulhos Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Sao Paulo Guarulhos Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Sao Paulo Guarulhos Intl Airport (DSM to GRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Sao Paulo Guarulhos Intl Airport

Fastest flight time

12h 51m

Direct flights

None
The fastest flight from Des Moines to Sao Paulo Guarulhos Intl Airport takes 12h 51m
There are no direct flights from Des Moines to Sao Paulo Guarulhos Intl Airport. There are no popular flight routes from Des Moines to Sao Paulo Guarulhos Intl Airport.
Search flight deals

  • How far is Des Moines to Sao Paulo Guarulhos Intl by plane?

    The distance between Des Moines and Sao Paulo Guarulhos Intl is about 5406.4 mi. A reasonable flight in good conditions will take 12h 51m.

  • When did momondo last update prices for flights from Des Moines Airport to Sao Paulo Guarulhos Intl Airport?

    Prices for flights from Des Moines Airport to Sao Paulo Guarulhos Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Des Moines Airport to Sao Paulo Guarulhos Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Sao Paulo Guarulhos Intl Airport.

  • What documentation or ID do you need to fly to Sao Paulo Guarulhos Intl Airport?

    The required travel and health documents for your Sao Paulo Guarulhos Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Sao Paulo Guarulhos Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • How do I get Price Alerts for flights from Des Moines to Sao Paulo Guarulhos Intl Airport?

    Confirm your travel details to search for the latest offers for flights from Des Moines to Sao Paulo Guarulhos Intl Airport. While browsing offers there will be the option to toggle “Price Alerts”. You’ll then receive updates when prices for the flight route increase or decrease.

  • How can I save money on flights from Des Moines to Sao Paulo Guarulhos Intl Airport with momondo?

    With “Price Forecast”, learn how soon you should book your flight in advance. Down to the day of week and time of day, our information can inform you on the ideal time to book to save on your travel. Our “Price Calendar” shows you at a quick glance when to book your travel for lower rates. By setting “Price Alerts” you can monitor changes in price and target the ideal time to book. Search for your trip destination by budget amount via our “Explore” feature. Whether you’re looking for ideas for your next travel adventure or cost-cutting tips, our “Discover” content is a great place to start.

  • How does momondo find its flight prices?

    momondo shows deals across 700+ competitors all at once. momondo is active in 30 international markets, so you can have access to a wide range of options from airlines and OTAs alike.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Guarulhos
Santos
Guarujá
Campinas
Aparecida

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Sao Paulo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Sao Paulo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Sao Paulo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Sao Paulo from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Sao Paulo?

momondo helps you find the best flight between Des Moines and Sao Paulo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Sao Paulo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Sao Paulo, momondo offers a useful price alert feature which will track prices for flights to Sao Paulo from Des Moines and alert you when they change.

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