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Cheap flights from Des Moines to Sao Paulo from $744

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Sao Paulo departing on 4/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:30 am - 8:40 pm
DSM
-
GRU
35h 10m
1 stop
Multiple Airlines Logo
2:20 am - 4:23 pm
GRU
-
DSM
40h 03m
2 stops
$1,024Multiple Airlines
Sun, Jun 21 - Mon, Jul 6
Multiple Airlines Logo
7:30 am - 8:40 pm
DSM
-
GRU
35h 10m
1 stop
Multiple Airlines Logo
2:20 am - 10:15 pm
GRU
-
DSM
21h 55m
2 stops
$1,048Multiple Airlines
Sun, Jun 21 - Thu, Jul 9
Multiple Airlines Logo
5:06 pm - 4:20 am
DSM
-
GRU
33h 14m
2 stops
Multiple Airlines Logo
8:30 am - 8:33 am
GRU
-
DSM
26h 03m
1 stop
$1,065Multiple Airlines
Sat, Jun 20 - Wed, Jul 8
Multiple Airlines Logo
7:30 am - 8:40 pm
DSM
-
GRU
35h 10m
1 stop
Multiple Airlines Logo
5:15 pm - 3:50 pm
GRU
-
DSM
48h 35m
2 stops
$1,103Multiple Airlines
Sun, Jun 21 - Wed, Jul 8
Multiple Airlines Logo
7:30 am - 8:40 pm
DSM
-
GRU
35h 10m
1 stop
Multiple Airlines Logo
2:20 am - 10:15 pm
GRU
-
DSM
21h 55m
2 stops
$1,110Multiple Airlines
Sun, Jun 21 - Sun, Jul 5
Multiple Airlines Logo
7:30 am - 8:40 pm
DSM
-
GRU
35h 10m
1 stop
Multiple Airlines Logo
2:20 am - 4:23 pm
GRU
-
DSM
40h 03m
2 stops
$1,126Multiple Airlines
Sun, Jun 28 - Mon, Jul 6
Multiple Airlines Logo
7:00 am - 8:40 pm
DSM
-
GRU
35h 40m
1 stop
Multiple Airlines Logo
11:50 am - 2:00 pm
GRU
-
DSM
28h 10m
2 stops
$1,127Multiple Airlines
Thu, May 14 - Thu, May 21
Multiple Airlines Logo
9:27 am - 4:20 am
DSM
-
GRU
16h 53m
2 stops
Multiple Airlines Logo
8:30 am - 8:33 am
GRU
-
DSM
26h 03m
1 stop
$1,129Multiple Airlines
Sun, Jun 28 - Wed, Jul 8
Multiple Airlines Logo
5:06 pm - 4:20 am
DSM
-
GRU
33h 14m
2 stops
Multiple Airlines Logo
11:40 am - 3:24 pm
GRU
-
DSM
29h 44m
1 stop
$1,130Multiple Airlines
Sat, Jun 20 - Mon, Jul 6
Multiple Airlines Logo
7:00 am - 8:40 pm
DSM
-
GRU
35h 40m
1 stop
Multiple Airlines Logo
11:50 am - 2:00 pm
GRU
-
DSM
28h 10m
2 stops
$1,133Multiple Airlines
Thu, May 14 - Thu, May 21

LATAM Airlines flights from Des Moines to Sao Paulo Guarulhos Intl Airport

Our best LATAM Airlines deals on Des Moines to Sao Paulo Guarulhos Intl Airport flight tickets
LATAM Airlines
Sep 13
DSM6:30 pmDes Moines
23h 30m
2 stops
GRU8:00 pmSao Paulo Guarulhos Intl
Sep 20
GRU11:45 pmSao Paulo Guarulhos Intl
19h 57m
2 stops
DSM5:42 pmDes Moines
$1,159
LATAM Airlines
Sep 13
DSM6:30 pmDes Moines
23h 30m
2 stops
GRU8:00 pmSao Paulo Guarulhos Intl
Sep 20
GRU9:30 pmSao Paulo Guarulhos Intl
41h 52m
2 stops
DSM1:22 pmDes Moines
$1,169
LATAM Airlines
Sep 13
DSM6:30 pmDes Moines
23h 30m
2 stops
GRU8:00 pmSao Paulo Guarulhos Intl
Sep 20
GRU10:50 pmSao Paulo Guarulhos Intl
13h 24m
1 stop
DSM10:14 amDes Moines
$1,199

American Airlines flights from Des Moines to Sao Paulo Guarulhos Intl Airport

Our best American Airlines deals on Des Moines to Sao Paulo Guarulhos Intl Airport flight tickets
American Airlines
Jul 15
DSM4:48 pmDes Moines
14h 12m
1 stop
GRU9:00 amSao Paulo Guarulhos Intl
Jul 31
GRU9:25 pmSao Paulo Guarulhos Intl
17h 31m
2 stops
DSM12:56 pmDes Moines
$1,250
American Airlines
Jul 15
DSM4:48 pmDes Moines
14h 12m
1 stop
GRU9:00 amSao Paulo Guarulhos Intl
Jul 31
GRU9:25 pmSao Paulo Guarulhos Intl
28h 16m
1 stop
DSM11:41 pmDes Moines
$1,261
American Airlines
Jun 22
DSM9:41 amDes Moines
21h 19m
1 stop
GRU9:00 amSao Paulo Guarulhos Intl
Jul 7
GRU10:00 pmSao Paulo Guarulhos Intl
20h 00m
1 stop
DSM4:00 pmDes Moines
$1,276

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Sao Paulo Guarulhos Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 31, 2026.
Use the filters below to find and compare flights from Des Moines to Sao Paulo Guarulhos Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 6/21

7:30 am-8:40 pm

1 stop35h 10m

Sao Paulo Guarulhos Intl

Mon 7/6

2:20 am-4:23 pm

2 stops40h 03m

$1,024

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 6/21

7:30 am-8:40 pm

1 stop35h 10m

Sao Paulo Guarulhos Intl

Thu 7/9

2:20 am-10:15 pm

2 stops21h 55m

$1,048

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sat 6/20

5:06 pm-4:20 am

2 stops33h 14m

Sao Paulo Guarulhos Intl

Wed 7/8

8:30 am-8:33 am

1 stop26h 03m

$1,065

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 6/21

7:30 am-8:40 pm

1 stop35h 10m

Sao Paulo Guarulhos Intl

Wed 7/8

5:15 pm-3:50 pm

2 stops48h 35m

$1,103

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 6/21

7:30 am-8:40 pm

1 stop35h 10m

Sao Paulo Guarulhos Intl

Sun 7/5

2:20 am-10:15 pm

2 stops21h 55m

$1,110

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 6/28

7:30 am-8:40 pm

1 stop35h 10m

Sao Paulo Guarulhos Intl

Mon 7/6

2:20 am-4:23 pm

2 stops40h 03m

$1,126

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 5/14

7:00 am-8:40 pm

1 stop35h 40m

Sao Paulo Guarulhos Intl

Thu 5/21

11:50 am-2:00 pm

2 stops28h 10m

$1,127
Quickest round-trip

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sun 6/28

9:27 am-4:20 am

2 stops16h 53m

Sao Paulo Guarulhos Intl

Wed 7/8

8:30 am-8:33 am

1 stop26h 03m

$1,129

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Sat 6/20

5:06 pm-4:20 am

2 stops33h 14m

Sao Paulo Guarulhos Intl

Mon 7/6

11:40 am-3:24 pm

1 stop29h 44m

$1,130

Des MoinesSao Paulo

DSM - GRU

DSMGRU

Des Moines

Thu 5/14

7:00 am-8:40 pm

1 stop35h 40m

Sao Paulo Guarulhos Intl

Thu 5/21

11:50 am-2:00 pm

2 stops28h 10m

$1,133

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Des Moines to Sao Paulo Guarulhos Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Sao Paulo Guarulhos Intl?

Avianca and United Airlines are the most popular carriers operating from Des Moines to Sao Paulo Guarulhos Intl

When to book flights from Des Moines to Sao Paulo Guarulhos Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Sao Paulo Guarulhos Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Sao Paulo Guarulhos Intl Airport (DSM to GRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Sao Paulo Guarulhos Intl Airport

Fastest flight time

18h 22m

Direct flights

None
The fastest flight from Des Moines to Sao Paulo Guarulhos Intl Airport takes 18h 22m
There are no direct flights from Des Moines to Sao Paulo Guarulhos Intl Airport. There are no popular flight routes from Des Moines to Sao Paulo Guarulhos Intl Airport.
Search flight deals

  • How far is Des Moines to Sao Paulo Guarulhos Intl by plane?

    The distance between Des Moines and Sao Paulo Guarulhos Intl is about 5406.4 mi. A reasonable flight in good conditions will take 18h 22m.

  • When did momondo last update prices for flights from Des Moines Airport to Sao Paulo Guarulhos Intl Airport?

    Prices for flights from Des Moines Airport to Sao Paulo Guarulhos Intl Airport are refreshed on a daily basis.

  • How old do you have to be to fly from Des Moines Airport to Sao Paulo Guarulhos Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Sao Paulo Guarulhos Intl Airport.

  • What documentation or ID do you need to fly to Sao Paulo Guarulhos Intl Airport?

    The required travel and health documents for your Sao Paulo Guarulhos Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Sao Paulo Guarulhos Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Santos
Guarulhos
Campinas
Guarujá
Aparecida

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Sao Paulo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Sao Paulo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Sao Paulo with flexible booking policies on momondo?

momondo does allow users to show only those flights to Sao Paulo from Des Moines which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Des Moines to Sao Paulo?

momondo helps you find the best flight between Des Moines and Sao Paulo by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Sao Paulo right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Sao Paulo, momondo offers a useful price alert feature which will track prices for flights to Sao Paulo from Des Moines and alert you when they change.

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