What is the cheapest airline that flies from Des Moines to Santiago Arturo Merino Benitez?

LATAM Airlines and American Airlines are the most popular carriers operating from Des Moines to Santiago Arturo Merino Benitez

When did momondo last update prices for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport are updated daily.

How many operators does momondo search for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport?

The number of operators available for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport is 1 as of May 2026.

How old do you have to be to fly from Des Moines Airport to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$547 Cheap Flights from Des Moines to Santiago in 2026

Q: What is the typical price of a round-trip flight between Des Moines and Santiago?

Prices are currently low for flights on this route. Typical prices usually range from $1,668 to $1,595. The lowest price recently found on this route was $1,183.

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Find the cheapest flights from Des Moines to Santiago

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:39 pm - 1:35 pm

DSM

SCL

41h 56m

2 stops

8:55 pm - 1:35 pm

SCL

DSM

41h 40m

2 stops

$1,183LATAM Airlines

Wed, Jun 10 - Wed, Jun 17

1:37 pm - 7:05 am

DSM

SCL

16h 28m

2 stops

9:00 pm - 6:22 pm

SCL

DSM

22h 22m

2 stops

$1,230American Airlines

Mon, Jun 1 - Mon, Jun 8

11:28 am - 6:50 am

DSM

SCL

18h 22m

2 stops

8:40 pm - 10:43 am

SCL

DSM

15h 03m

1 stop

$1,232LATAM Airlines

Thu, Jun 18 - Thu, Jun 25

11:28 am - 6:50 am

DSM

SCL

18h 22m

2 stops

11:05 pm - 10:49 am

SCL

DSM

36h 44m

2 stops

$1,235LATAM Airlines

Thu, Jun 18 - Thu, Jun 25

2:33 pm - 6:55 am

DSM

SCL

15h 22m

2 stops

8:40 pm - 1:35 pm

SCL

DSM

17h 55m

1 stop

$1,241LATAM Airlines

Wed, Jun 3 - Wed, Jun 10

2:25 pm - 7:15 am

DSM

SCL

15h 50m

1 stop

8:40 pm - 10:43 am

SCL

DSM

15h 03m

1 stop

$1,242LATAM Airlines

Thu, Jun 18 - Thu, Jun 25

11:28 am - 6:50 am

DSM

SCL

18h 22m

2 stops

8:30 am - 10:43 am

SCL

DSM

27h 13m

3 stops

$1,260LATAM Airlines

Thu, Jun 18 - Thu, Jun 25

2:25 pm - 7:15 am

DSM

SCL

15h 50m

1 stop

8:55 pm - 1:35 pm

SCL

DSM

41h 40m

2 stops

$1,262LATAM Airlines

Wed, Jun 10 - Wed, Jun 17

2:25 pm - 1:25 pm

DSM

SCL

22h 00m

2 stops

8:40 pm - 10:43 am

SCL

DSM

15h 03m

1 stop

$1,263LATAM Airlines

Thu, Jun 18 - Thu, Jun 25

5:35 am - 4:50 am

DSM

SCL

22h 15m

2 stops

8:40 pm - 10:43 am

SCL

DSM

15h 03m

1 stop

$1,265Delta

Thu, Jun 18 - Thu, Jun 25

LATAM Airlines flights from Des Moines to Santiago

Our best LATAM Airlines deals on Des Moines to Santiago flight tickets

LATAM Airlines

Jun 10

DSM6:39 pmDes Moines

41h 56m

2 stops

SCL1:35 pmSantiago Arturo Merino Benitez

Jun 17

SCL8:55 pmSantiago Arturo Merino Benitez

41h 40m

2 stops

DSM1:35 pmDes Moines

$1,183

LATAM Airlines

Jun 18

DSM11:28 amDes Moines

18h 22m

2 stops

SCL6:50 amSantiago Arturo Merino Benitez

Jun 25

SCL8:40 pmSantiago Arturo Merino Benitez

15h 03m

1 stop

DSM10:43 amDes Moines

$1,232

LATAM Airlines

Jun 18

DSM11:28 amDes Moines

18h 22m

2 stops

SCL6:50 amSantiago Arturo Merino Benitez

Jun 25

SCL11:05 pmSantiago Arturo Merino Benitez

36h 44m

2 stops

DSM10:49 amDes Moines

$1,235

Delta flights from Des Moines to Santiago

Our best Delta deals on Des Moines to Santiago flight tickets

Delta

Jun 18

DSM5:35 amDes Moines

22h 15m

2 stops

SCL4:50 amSantiago Arturo Merino Benitez

Jun 25

SCL8:40 pmSantiago Arturo Merino Benitez

15h 03m

1 stop

DSM10:43 amDes Moines

$1,265

Delta

Jun 19

DSM11:28 amDes Moines

16h 22m

2 stops

SCL4:50 amSantiago Arturo Merino Benitez

Jun 26

SCL8:40 pmSantiago Arturo Merino Benitez

15h 09m

1 stop

DSM10:49 amDes Moines

$1,365

Delta

Jun 20

DSM4:47 pmDes Moines

13h 28m

1 stop

SCL7:15 amSantiago Arturo Merino Benitez

Jun 27

SCL8:40 pmSantiago Arturo Merino Benitez

15h 05m

1 stop

DSM10:45 amDes Moines

$1,465

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 6/10

6:39 pm-1:35 pm

2 stops41h 56m

Santiago Arturo Merino Benitez

Wed 6/17

8:55 pm-1:35 pm

2 stops41h 40m

$1,183

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Mon 6/1

1:37 pm-7:05 am

2 stops16h 28m

Santiago Arturo Merino Benitez

Mon 6/8

9:00 pm-6:22 pm

2 stops22h 22m

$1,230

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 6/18

11:28 am-6:50 am

2 stops18h 22m

Santiago Arturo Merino Benitez

Thu 6/25

8:40 pm-10:43 am

1 stop15h 03m

$1,232

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 6/18

11:28 am-6:50 am

2 stops18h 22m

Santiago Arturo Merino Benitez

Thu 6/25

11:05 pm-10:49 am

2 stops36h 44m

$1,235

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 6/3

2:33 pm-6:55 am

2 stops15h 22m

Santiago Arturo Merino Benitez

Wed 6/10

8:40 pm-1:35 pm

1 stop17h 55m

$1,241

Quickest round-trip

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 6/18

2:25 pm-7:15 am

1 stop15h 50m

Santiago Arturo Merino Benitez

Thu 6/25

8:40 pm-10:43 am

1 stop15h 03m

$1,242

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 6/18

11:28 am-6:50 am

2 stops18h 22m

Santiago Arturo Merino Benitez

Thu 6/25

8:30 am-10:43 am

3 stops27h 13m

$1,260

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 6/10

2:25 pm-7:15 am

1 stop15h 50m

Santiago Arturo Merino Benitez

Wed 6/17

8:55 pm-1:35 pm

2 stops41h 40m

$1,262

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 6/18

2:25 pm-1:25 pm

2 stops22h 00m

Santiago Arturo Merino Benitez

Thu 6/25

8:40 pm-10:43 am

1 stop15h 03m

$1,263

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 6/18

5:35 am-4:50 am

2 stops22h 15m

Santiago Arturo Merino Benitez

Thu 6/25

8:40 pm-10:43 am

1 stop15h 03m

$1,265

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between Des Moines and Santiago?

What is the cheapest month to fly to Santiago?

In general, September is the cheapest month to fly from Des Moines to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $0. If you don’t want to visit Santiago in September, then you should wait until February to fly from Des Moines, when ticket prices are also cheap, with an average price of $0.

Can stopping save me money on Des Moines to Santiago flights?

You could potentially save up to 1% on your flight if you consider stops on a Des Moines to Santiago flight.

When to book flights from Des Moines to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Santiago (DSM to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Santiago

Fastest flight time	23h 08m
Direct flights	None

The fastest flight from Des Moines to Santiago takes 23h 08m

There are no direct flights from Des Moines to Santiago. There are no popular flight routes from Des Moines to Santiago.

Search flight deals

Frequently asked questions about flying from Des Moines to Santiago

How far is Des Moines to Santiago Arturo Merino Benitez by plane?
Des Moines and Santiago Arturo Merino Benitez are 5382.1 mi apart from one another. 23h 08m is a normal flight duration for this route.
When did momondo last update prices for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport are updated daily.
How many operators does momondo search for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport?
The number of operators available for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport is 1 as of May 2026.
How old do you have to be to fly from Des Moines Airport to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Des Moines to Santiago?
Based on momondo bookings for flights between Des Moines and Santiago, the leading airline is LATAM Airlines, making up 100% of the total bookings.

Best airlines flying from Des Moines to Santiago

Compare and see reviews for airlines that fly from Des Moines to Santiago with momondo

Airline	Rating	Free Cancellation	Price
LATAM Airlines	PriceFrom $814	Free Cancellation	Rating 7.4 1,917 reviews		Search LATAM Airlines flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

Pichilemu

San Fernando

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from Des Moines.

Can I find flights from Des Moines to Santiago with flexible booking policies on momondo?

Flights from Des Moines to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Santiago?

momondo helps you find the best flight between Des Moines and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from Des Moines and alert you when they change.