What is the cheapest airline that flies from Des Moines to Santiago Arturo Merino Benitez?

Delta is the most popular carrier operating from Des Moines to Santiago Arturo Merino Benitez

When did momondo last update prices for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport are updated daily.

How many operators does momondo search for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport?

The number of operators available for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport is 1 as of March 2026.

How old do you have to be to fly from Des Moines Airport to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$326 Cheap Flights from Des Moines to Santiago in 2026

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Find the cheapest flights from Des Moines to Santiago

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:25 pm - 7:05 am

DSM

SCL

16h 40m

2 stops

8:35 pm - 4:31 pm

SCL

DSM

20h 56m

2 stops

$921American Airlines

Tue, May 5 - Tue, May 12

11:57 am - 5:45 am

DSM

SCL

16h 48m

2 stops

11:00 pm - 5:53 pm

SCL

DSM

19h 53m

2 stops

$922LATAM Airlines

Thu, May 7 - Thu, May 14

11:51 am - 5:25 am

DSM

SCL

16h 34m

2 stops

11:05 pm - 5:53 pm

SCL

DSM

19h 48m

2 stops

$923LATAM Airlines

Wed, May 6 - Wed, May 13

2:44 pm - 6:55 am

DSM

SCL

15h 11m

2 stops

11:05 pm - 5:53 pm

SCL

DSM

19h 48m

2 stops

$927LATAM Airlines

Wed, May 6 - Wed, May 13

5:27 am - 6:00 am

DSM

SCL

23h 33m

2 stops

7:55 pm - 11:08 am

SCL

DSM

16h 13m

2 stops

$928Delta

Thu, May 7 - Thu, May 14

2:44 pm - 6:55 am

DSM

SCL

15h 11m

2 stops

8:40 pm - 11:08 am

SCL

DSM

15h 28m

1 stop

$931LATAM Airlines

Wed, May 6 - Wed, May 13

2:44 pm - 7:15 am

DSM

SCL

15h 31m

1 stop

7:55 pm - 11:08 am

SCL

DSM

16h 13m

2 stops

$944LATAM Airlines

Tue, May 5 - Tue, May 12

5:45 am - 5:35 am

DSM

SCL

22h 50m

2 stops

11:05 pm - 5:53 pm

SCL

DSM

19h 48m

2 stops

$946LATAM Airlines

Tue, May 5 - Tue, May 12

11:51 am - 5:25 am

DSM

SCL

16h 34m

2 stops

8:40 pm - 11:08 am

SCL

DSM

15h 28m

1 stop

$949LATAM Airlines

Wed, May 6 - Wed, May 13

7:11 am - 7:05 am

DSM

SCL

22h 54m

2 stops

8:35 pm - 12:52 pm

SCL

DSM

17h 17m

2 stops

$950American Airlines

Mon, May 4 - Mon, May 11

American Airlines flights from Des Moines to Santiago

Our best American Airlines deals on Des Moines to Santiago flight tickets

American Airlines

May 5

DSM1:25 pmDes Moines

16h 40m

2 stops

SCL7:05 amSantiago Arturo Merino Benitez

May 12

SCL8:35 pmSantiago Arturo Merino Benitez

20h 56m

2 stops

DSM4:31 pmDes Moines

$921

American Airlines

May 4

DSM7:11 amDes Moines

22h 54m

2 stops

SCL7:05 amSantiago Arturo Merino Benitez

May 11

SCL8:35 pmSantiago Arturo Merino Benitez

17h 17m

2 stops

DSM12:52 pmDes Moines

$950

American Airlines

May 6

DSM12:06 pmDes Moines

17h 59m

2 stops

SCL7:05 amSantiago Arturo Merino Benitez

May 13

SCL8:35 pmSantiago Arturo Merino Benitez

17h 36m

2 stops

DSM1:11 pmDes Moines

$955

LATAM Airlines flights from Des Moines to Santiago

Our best LATAM Airlines deals on Des Moines to Santiago flight tickets

LATAM Airlines

May 7

DSM11:57 amDes Moines

16h 48m

2 stops

SCL5:45 amSantiago Arturo Merino Benitez

May 14

SCL11:00 pmSantiago Arturo Merino Benitez

19h 53m

2 stops

DSM5:53 pmDes Moines

$922

LATAM Airlines

May 6

DSM11:51 amDes Moines

16h 34m

2 stops

SCL5:25 amSantiago Arturo Merino Benitez

May 13

SCL11:05 pmSantiago Arturo Merino Benitez

19h 48m

2 stops

DSM5:53 pmDes Moines

$923

LATAM Airlines

May 6

DSM2:44 pmDes Moines

15h 11m

2 stops

SCL6:55 amSantiago Arturo Merino Benitez

May 13

SCL8:40 pmSantiago Arturo Merino Benitez

15h 28m

1 stop

DSM11:08 amDes Moines

$927

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Tue 5/5

1:25 pm-7:05 am

2 stops16h 40m

Santiago Arturo Merino Benitez

Tue 5/12

8:35 pm-4:31 pm

2 stops20h 56m

$921

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 5/7

11:57 am-5:45 am

2 stops16h 48m

Santiago Arturo Merino Benitez

Thu 5/14

11:00 pm-5:53 pm

2 stops19h 53m

$922

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 5/6

11:51 am-5:25 am

2 stops16h 34m

Santiago Arturo Merino Benitez

Wed 5/13

11:05 pm-5:53 pm

2 stops19h 48m

$923

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 5/6

2:44 pm-6:55 am

2 stops15h 11m

Santiago Arturo Merino Benitez

Wed 5/13

11:05 pm-5:53 pm

2 stops19h 48m

$927

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 5/7

5:27 am-6:00 am

2 stops23h 33m

Santiago Arturo Merino Benitez

Thu 5/14

7:55 pm-11:08 am

2 stops16h 13m

$928

Quickest round-trip

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 5/6

2:44 pm-6:55 am

2 stops15h 11m

Santiago Arturo Merino Benitez

Wed 5/13

8:40 pm-11:08 am

1 stop15h 28m

$931

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Tue 5/5

2:44 pm-7:15 am

1 stop15h 31m

Santiago Arturo Merino Benitez

Tue 5/12

7:55 pm-11:08 am

2 stops16h 13m

$944

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Tue 5/5

5:45 am-5:35 am

2 stops22h 50m

Santiago Arturo Merino Benitez

Tue 5/12

11:05 pm-5:53 pm

2 stops19h 48m

$946

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Wed 5/6

11:51 am-5:25 am

2 stops16h 34m

Santiago Arturo Merino Benitez

Wed 5/13

8:40 pm-11:08 am

1 stop15h 28m

$949

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Mon 5/4

7:11 am-7:05 am

2 stops22h 54m

Santiago Arturo Merino Benitez

Mon 5/11

8:35 pm-12:52 pm

2 stops17h 17m

$950

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Des Moines to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Can stopping save me money on Des Moines to Santiago flights?

You could potentially save up to 36% on your flight if you consider stops on a Des Moines to Santiago flight.

When to book flights from Des Moines to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Des Moines to Santiago (DSM to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Santiago

Fastest flight time	23h 33m
Direct flights	None

The fastest flight from Des Moines to Santiago takes 23h 33m

There are no direct flights from Des Moines to Santiago. There are no popular flight routes from Des Moines to Santiago.

Search flight deals

How far is Des Moines to Santiago Arturo Merino Benitez by plane?
Des Moines and Santiago Arturo Merino Benitez are 5382.1 mi apart from one another. 23h 33m is a normal flight duration for this route.
When did momondo last update prices for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport are updated daily.
How many operators does momondo search for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport?
The number of operators available for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport is 1 as of March 2026.
How old do you have to be to fly from Des Moines Airport to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular airline from Des Moines to Santiago?
Based on momondo bookings for flights between Des Moines and Santiago, the leading airline is LATAM Airlines, making up 100% of the total bookings.

Best airlines flying from Des Moines to Santiago

Compare and see reviews for airlines that fly from Des Moines to Santiago with momondo

Airline	Rating	Free Cancellation	Price
LATAM Airlines	PriceFrom $814	Free Cancellation	Rating 7.4 1,905 reviews		Search LATAM Airlines flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from Des Moines.

Can I find flights from Des Moines to Santiago with flexible booking policies on momondo?

Flights from Des Moines to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Santiago?

momondo helps you find the best flight between Des Moines and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from Des Moines and alert you when they change.