Cheap flights from Des Moines to Santiago from $464

1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Des Moines to Santiago

Cheap round-trip flights

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American Airlines Logo
6:00 am - 8:35 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
23h 35m1 stop Dallas/Fort Worth
American Airlines Logo
10:15 pm - 11:16 pmSCL  Santiago Arturo Merino Benitez-DSM Des Moines
27h 01m2 stops Miami Dallas/Fort Worth
$1,272American Airlines
Mon, Jan 18 - Fri, Mar 26
American Airlines Logo
9:45 am - 8:35 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
19h 50m1 stop Dallas/Fort Worth
American Airlines Logo
10:15 pm - 12:59 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
28h 44m1 stop Miami
$1,283American Airlines
Mon, Jan 18 - Fri, Mar 26
LATAM Airlines Logo
11:04 am - 3:00 pmDSM  Des Moines-SCL Santiago Arturo Merino Benitez
25h 56m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl
LATAM Airlines Logo
1:01 am - 10:18 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
35h 17m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson
$1,298LATAM Airlines
Fri, Mar 26 - Mon, Mar 29
LATAM Airlines Logo
5:45 am - 7:30 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
23h 45m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado
LATAM Airlines Logo
8:15 am - 10:18 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
28h 03m3 stops Buenos Aires Ministro Pistarini Miami Atlanta Hartsfield-Jackson
$1,302LATAM Airlines
Fri, Mar 26 - Tue, Mar 30
Delta Logo
11:04 am - 7:00 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
16h 56m2 stops Atlanta Hartsfield-Jackson Miami
Delta Logo
7:55 am - 10:18 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
28h 23m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson
$1,332Delta
Fri, Mar 12 - Fri, Mar 19
LATAM Airlines Logo
11:46 am - 3:00 pmDSM  Des Moines-SCL Santiago Arturo Merino Benitez
24h 14m3 stops Atlanta Hartsfield-Jackson Miami Buenos Aires Ministro Pistarini
LATAM Airlines Logo
8:35 am - 10:18 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
27h 43m3 stops Buenos Aires Ministro Pistarini Miami Atlanta Hartsfield-Jackson
$1,333LATAM Airlines
Mon, Jan 18 - Fri, Mar 26
LATAM Airlines Logo
5:15 pm - 7:00 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
34h 45m2 stops Atlanta Hartsfield-Jackson Miami
LATAM Airlines Logo
8:15 am - 10:18 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
28h 03m3 stops Punta Cana Miami Atlanta Hartsfield-Jackson
$1,363LATAM Airlines
Fri, Mar 12 - Sat, Mar 20
Delta Logo
11:38 am - 6:40 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
16h 02m1 stop Atlanta Hartsfield-Jackson
Delta Logo
12:35 am - 5:31 pmSCL  Santiago Arturo Merino Benitez-DSM Des Moines
19h 56m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson
$1,368Delta
Wed, Dec 23 - Tue, Dec 29
Delta Logo
5:30 am - 5:55 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
21h 25m2 stops Atlanta Hartsfield-Jackson Miami
Delta Logo
9:50 pm - 11:56 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
17h 06m2 stops Atlanta Hartsfield-Jackson Minneapolis St Paul
$1,372Delta
Wed, Dec 23 - Wed, Dec 30
LATAM Airlines Logo
11:04 am - 7:00 amDSM  Des Moines-SCL Santiago Arturo Merino Benitez
16h 56m2 stops Atlanta Hartsfield-Jackson Miami
LATAM Airlines Logo
7:55 am - 10:18 amSCL  Santiago Arturo Merino Benitez-DSM Des Moines
28h 23m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson
$1,387LATAM Airlines
Fri, Mar 12 - Sat, Mar 20

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LATAM Airlines flights from Des Moines to Santiago

Our best LATAM Airlines deals on Des Moines to Santiago flight tickets
LATAM Airlines
Mar 26
DSM5:45 amDes Moines
22h 55m
1 stop
SCL6:40 amSantiago Arturo Merino Benitez
Mar 30
SCL2:40 pmSantiago Arturo Merino Benitez
21h 38m
2 stops
DSM10:18 amDes Moines
$1,298
LATAM Airlines
Mar 26
DSM5:45 amDes Moines
23h 45m
2 stops
SCL7:30 amSantiago Arturo Merino Benitez
Mar 30
SCL8:15 amSantiago Arturo Merino Benitez
28h 03m
3 stops
DSM10:18 amDes Moines
$1,302
LATAM Airlines
Jan 18
DSM11:46 amDes Moines
24h 14m
3 stops
SCL3:00 pmSantiago Arturo Merino Benitez
Mar 26
SCL8:35 amSantiago Arturo Merino Benitez
27h 43m
3 stops
DSM10:18 amDes Moines
$1,333

American Airlines flights from Des Moines to Santiago

Our best American Airlines deals on Des Moines to Santiago flight tickets
American Airlines
Jan 18
DSM6:00 amDes Moines
23h 35m
1 stop
SCL8:35 amSantiago Arturo Merino Benitez
Mar 26
SCL10:15 pmSantiago Arturo Merino Benitez
27h 01m
2 stops
DSM11:16 pmDes Moines
$1,272
American Airlines
Jan 18
DSM9:45 amDes Moines
19h 50m
1 stop
SCL8:35 amSantiago Arturo Merino Benitez
Mar 26
SCL10:15 pmSantiago Arturo Merino Benitez
28h 44m
1 stop
DSM12:59 amDes Moines
$1,283
American Airlines
Dec 18
DSM7:02 amDes Moines
23h 18m
2 stops
SCL9:20 amSantiago Arturo Merino Benitez
Jan 10
SCL11:15 pmSantiago Arturo Merino Benitez
21h 14m
1 stop
DSM5:29 pmDes Moines
$2,198

momondo Fare Finder

 
Use the filters below to find and compare flights from Des Moines to Santiago that are best for you.

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Route

Depart

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Price

Cheapest round-trip

Des MoinesSantiago

DSM Des Moines - SCL Santiago Arturo Merino Benitez

DSMSCL

Des Moines

Mon 1/18

6:00 am-8:35 am

1 stop23h 35m

Santiago Arturo Merino Benitez

Fri 3/26

10:15 pm-11:16 pm

2 stops27h 01m

$1,272

Des MoinesSantiago

DSM Des Moines - SCL Santiago Arturo Merino Benitez

DSMSCL

Des Moines

Mon 1/18

9:45 am-8:35 am

1 stop19h 50m

Santiago Arturo Merino Benitez

Fri 3/26

10:15 pm-12:59 am

1 stop28h 44m

$1,283

Des MoinesSantiago

DSM Des Moines - SCL Santiago Arturo Merino Benitez

DSMSCL

Des Moines

Fri 3/26

11:04 am-3:00 pm

2 stops25h 56m

Santiago Arturo Merino Benitez

Mon 3/29

1:01 am-10:18 am

2 stops35h 17m

$1,298

Des MoinesSantiago

DSM Des Moines - SCL Santiago Arturo Merino Benitez

DSMSCL

Des Moines

Fri 3/26

5:45 am-7:30 am

2 stops23h 45m

Santiago Arturo Merino Benitez

Tue 3/30

8:15 am-10:18 am

3 stops28h 03m

$1,302

Des MoinesSantiago

DSM Des Moines - SCL Santiago Arturo Merino Benitez

DSMSCL

Des Moines

Fri 3/12

11:04 am-7:00 am

2 stops16h 56m

Santiago Arturo Merino Benitez

Fri 3/19

7:55 am-10:18 am

2 stops28h 23m

$1,332

Des MoinesSantiago

DSM Des Moines - SCL Santiago Arturo Merino Benitez

DSMSCL

Des Moines

Mon 1/18

11:46 am-3:00 pm

3 stops24h 14m

Santiago Arturo Merino Benitez

Fri 3/26

8:35 am-10:18 am

3 stops27h 43m

$1,333

Des MoinesSantiago

DSM Des Moines - SCL Santiago Arturo Merino Benitez

DSMSCL

Des Moines

Fri 3/12

5:15 pm-7:00 am

2 stops34h 45m

Santiago Arturo Merino Benitez

Sat 3/20

8:15 am-10:18 am

3 stops28h 03m

$1,363
Quickest round-trip

Des MoinesSantiago

DSM Des Moines - SCL Santiago Arturo Merino Benitez

DSMSCL

Des Moines

Wed 12/23

11:38 am-6:40 am

1 stop16h 02m

Santiago Arturo Merino Benitez

Tue 12/29

12:35 am-5:31 pm

2 stops19h 56m

$1,368

Des MoinesSantiago

DSM Des Moines - SCL Santiago Arturo Merino Benitez

DSMSCL

Des Moines

Wed 12/23

5:30 am-5:55 am

2 stops21h 25m

Santiago Arturo Merino Benitez

Wed 12/30

9:50 pm-11:56 am

2 stops17h 06m

$1,372

Des MoinesSantiago

DSM Des Moines - SCL Santiago Arturo Merino Benitez

DSMSCL

Des Moines

Fri 3/12

11:04 am-7:00 am

2 stops16h 56m

Santiago Arturo Merino Benitez

Sat 3/20

7:55 am-10:18 am

2 stops28h 23m

$1,387

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Des Moines to Santiago

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Can stopping save me money on Des Moines to Santiago flights?

You could potentially save up to 3% on your flight if you consider stops on a Des Moines to Santiago flight.

When to book flights from Des Moines to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Santiago (DSM to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Santiago

Best Price Found

$464

Fastest flight time

12h 55m

Direct flights

None
The best one-way flight to Santiago from Des Moines in the past 72 hours is $464. The best round-trip flight deal from Des Moines to Santiago found on momondo in the last 72 hours is $1,272.
The fastest flight from Des Moines to Santiago takes 12h 55m
There are no direct flights from Des Moines to Santiago. There are no popular flight routes from Des Moines to Santiago.

Frequently asked questions about flying from Des Moines to Santiago

  • How far is Des Moines to Santiago Arturo Merino Benitez by plane?

    Des Moines and Santiago Arturo Merino Benitez are 5382.1 mi apart from one another. 12h 55m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Des Moines Airport to Santiago Arturo Merino Benitez Airport are updated daily.

  • How old do you have to be to fly from Des Moines Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The necessary travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Valparaíso
Viña del Mar
Santa Cruz
San Fernando
Valle Nevado
Pichilemu
Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Santiago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago from Des Moines.

Can I find flights from Des Moines to Santiago with flexible booking policies on momondo?

Flights from Des Moines to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Santiago?

momondo helps you find the best flight between Des Moines and Santiago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Des Moines to Santiago right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago, momondo offers a useful price alert feature which will track prices for flights to Santiago from Des Moines and alert you when they change.

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Thu 12/10
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