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Cheap flights from Des Moines to Guatemala from $306

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Guatemala departing on 4/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Guatemala

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
6:48 pm - 12:35 pm
DSM
-
GUA
18h 47m
2 stops
Multiple Airlines Logo
1:41 pm - 3:15 pm
GUA
-
DSM
24h 34m
1 stop
$443Multiple Airlines
Fri, May 8 - Sat, May 16
Multiple Airlines Logo
6:48 pm - 12:35 pm
DSM
-
GUA
18h 47m
2 stops
Multiple Airlines Logo
1:41 pm - 3:15 pm
GUA
-
DSM
24h 34m
1 stop
$446Multiple Airlines
Fri, May 8 - Sat, May 16
Multiple Airlines Logo
7:00 am - 8:45 am
DSM
-
GUA
26h 45m
2 stops
Multiple Airlines Logo
1:41 pm - 3:15 pm
GUA
-
DSM
24h 34m
1 stop
$495Multiple Airlines
Sun, May 10 - Sat, May 16
Multiple Airlines Logo
7:00 am - 8:45 am
DSM
-
GUA
26h 45m
2 stops
Multiple Airlines Logo
1:41 pm - 3:15 pm
GUA
-
DSM
24h 34m
1 stop
$496Multiple Airlines
Sun, May 10 - Sat, May 16
Multiple Airlines Logo
6:20 am - 11:10 pm
DSM
-
GUA
17h 50m
2 stops
Multiple Airlines Logo
5:25 am - 10:35 pm
GUA
-
DSM
16h 10m
2 stops
$626Multiple Airlines
Sun, May 24 - Sun, May 31
Delta Logo
5:27 am - 11:31 am
DSM
-
GUA
7h 04m
1 stop
Delta Logo
1:01 pm - 10:32 pm
GUA
-
DSM
8h 31m
1 stop
$633Delta
Mon, May 11 - Mon, May 18
Multiple Airlines Logo
3:21 pm - 12:04 am
DSM
-
GUA
9h 43m
1 stop
Multiple Airlines Logo
12:23 pm - 8:13 pm
GUA
-
DSM
30h 50m
2 stops
$638Multiple Airlines
Thu, Apr 2 - Sat, Apr 11
American Airlines Logo
7:05 pm - 11:50 am
DSM
-
GUA
17h 45m
2 stops
American Airlines Logo
1:47 pm - 11:59 pm
GUA
-
DSM
9h 12m
1 stop
$657American Airlines
Mon, May 11 - Mon, May 18
Multiple Airlines Logo
10:21 am - 12:04 am
DSM
-
GUA
14h 43m
2 stops
Multiple Airlines Logo
12:59 am - 10:51 pm
GUA
-
DSM
20h 52m
1 stop
$659Multiple Airlines
Wed, Apr 1 - Sat, Apr 4
American Airlines Logo
7:05 am - 6:43 pm
DSM
-
GUA
12h 38m
2 stops
American Airlines Logo
3:14 pm - 8:26 am
GUA
-
DSM
16h 12m
2 stops
$674American Airlines
Thu, May 7 - Thu, May 14

Delta flights from Des Moines to Guatemala

Our best Delta deals on Des Moines to Guatemala flight tickets
Delta
May 11
DSM5:27 amDes Moines
7h 04m
1 stop
GUA11:31 amGuatemala City La Aurora
May 18
GUA1:01 pmGuatemala City La Aurora
8h 31m
1 stop
DSM10:32 pmDes Moines
$633
Delta
May 10
DSM5:28 pmDes Moines
19h 03m
2 stops
GUA11:31 amGuatemala City La Aurora
May 17
GUA1:01 pmGuatemala City La Aurora
8h 31m
1 stop
DSM10:32 pmDes Moines
$751
Delta
May 10
DSM5:27 amDes Moines
7h 04m
1 stop
GUA11:31 amGuatemala City La Aurora
May 17
GUA1:01 pmGuatemala City La Aurora
8h 31m
1 stop
DSM10:32 pmDes Moines
$767

American Airlines flights from Des Moines to Guatemala

Our best American Airlines deals on Des Moines to Guatemala flight tickets
American Airlines
Jul 15
DSM5:00 amDes Moines
15h 35m
2 stops
GUA7:35 pmGuatemala City La Aurora
Jul 29
GUA12:35 amGuatemala City La Aurora
16h 58m
1 stop
DSM6:33 pmDes Moines
$646
American Airlines
May 11
DSM7:05 pmDes Moines
17h 45m
2 stops
GUA11:50 amGuatemala City La Aurora
May 18
GUA1:47 pmGuatemala City La Aurora
9h 12m
1 stop
DSM11:59 pmDes Moines
$657
American Airlines
May 7
DSM7:05 amDes Moines
12h 38m
2 stops
GUA6:43 pmGuatemala City La Aurora
May 14
GUA3:14 pmGuatemala City La Aurora
16h 12m
2 stops
DSM8:26 amDes Moines
$674

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Guatemala that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 25, 2026.
Use the filters below to find and compare flights from Des Moines to Guatemala that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Fri 5/8

6:48 pm-12:35 pm

2 stops18h 47m

Guatemala City La Aurora

Sat 5/16

1:41 pm-3:15 pm

1 stop24h 34m

$443

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Fri 5/8

6:48 pm-12:35 pm

2 stops18h 47m

Guatemala City La Aurora

Sat 5/16

1:41 pm-3:15 pm

1 stop24h 34m

$446

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 5/10

7:00 am-8:45 am

2 stops26h 45m

Guatemala City La Aurora

Sat 5/16

1:41 pm-3:15 pm

1 stop24h 34m

$495

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 5/10

7:00 am-8:45 am

2 stops26h 45m

Guatemala City La Aurora

Sat 5/16

1:41 pm-3:15 pm

1 stop24h 34m

$496

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Sun 5/24

6:20 am-11:10 pm

2 stops17h 50m

Guatemala City La Aurora

Sun 5/31

5:25 am-10:35 pm

2 stops16h 10m

$626
Quickest round-trip

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 5/11

5:27 am-11:31 am

1 stop7h 04m

Guatemala City La Aurora

Mon 5/18

1:01 pm-10:32 pm

1 stop8h 31m

$633

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 4/2

3:21 pm-12:04 am

1 stop9h 43m

Guatemala City La Aurora

Sat 4/11

12:23 pm-8:13 pm

2 stops30h 50m

$638

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Mon 5/11

7:05 pm-11:50 am

2 stops17h 45m

Guatemala City La Aurora

Mon 5/18

1:47 pm-11:59 pm

1 stop9h 12m

$657

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Wed 4/1

10:21 am-12:04 am

2 stops14h 43m

Guatemala City La Aurora

Sat 4/4

12:59 am-10:51 pm

1 stop20h 52m

$659

Des MoinesGuatemala City

DSM - GUA

DSMGUA

Des Moines

Thu 5/7

7:05 am-6:43 pm

2 stops12h 38m

Guatemala City La Aurora

Thu 5/14

3:14 pm-8:26 am

2 stops16h 12m

$674

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 15 resultsSorted by cheapest first
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See travel insights to Guatemala from

How to get the cheapest flight ticket from Des Moines to Guatemala

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Guatemala?

In general, February is the cheapest month to fly from Des Moines to Guatemala. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $468. The month of September is another great option to travel to Guatemala, with average flight prices from Des Moines averaging around $493.

Cheap Des Moines to Guatemala flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Guatemala

Fastest flight time

6h 43m

Direct flights

None
The fastest flight from Des Moines to Guatemala takes 6h 43m
There are no direct flights from Des Moines to Guatemala. There are no popular flight routes from Des Moines to Guatemala.
Search flight deals

  • When did momondo last update prices for flights from Des Moines Airport to Guatemala?

    Prices for flights from Des Moines Airport to Guatemala are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Guatemala?

  • How old do you have to be to fly from Des Moines Airport to Guatemala?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Guatemala.

  • What documentation or ID do you need to fly to Guatemala?

    The travel and health documents required for your trip to Guatemala can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guatemala. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

Best airlines flying from Des Moines to Guatemala

Compare and see reviews for airlines that fly from Des Moines to Guatemala with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $468Free CancellationRating
7.1
11,493 reviews
Search American Airlines flights
United AirlinesPriceFrom $494Free CancellationRating
7.4
9,478 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Guatemala?

It is quick and easy to find Des Moines to Guatemala flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Guatemala that suits you.

Can I find flights from Des Moines to Guatemala with flexible booking policies on momondo?

All flight searches from Des Moines to Guatemala on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Des Moines to Guatemala?

Once you have performed a search for Des Moines to Guatemala flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Des Moines to Guatemala right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Des Moines to Guatemala now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Guatemala and let you know when they change.

An easier way to manage your Guatemala trip

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Fri 4/24
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