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Cheap flights from Des Moines to Guadalajara from $203

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Guadalajara departing on 9/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Guadalajara

Cheap round-trip flights

Logo
8:00 am - 8:15 pmDSM-GDL
13h 15m2 stops
Logo
8:54 am - 10:29 pmGDL-DSM
12h 35m1 stop
$440
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Thu, Sep 4 - Fri, Sep 5
Logo
7:00 am - 5:03 amDSM-GDL
23h 03m1 stop
Logo
10:20 am - 10:29 pmGDL-DSM
11h 09m1 stop
$458
Find Deal
Thu, Sep 4 - Fri, Sep 5
Frontier Logo
2:25 pm - 1:24 pmDSM-GDL
23h 59m2 stops
Frontier Logo
7:08 am - 1:40 pmGDL-DSM
29h 32m2 stops
$508Frontier
Find Deal
Sun, Sep 14 - Sun, Sep 21
Frontier Logo
8:44 pm - 10:23 pmDSM-GDL
26h 39m2 stops
Frontier Logo
3:18 pm - 7:59 pmGDL-DSM
27h 41m2 stops
$529Frontier
Find Deal
Fri, Oct 17 - Sun, Oct 26
American Airlines Logo
4:09 pm - 11:24 pmDSM-GDL
8h 15m1 stop
American Airlines Logo
6:00 am - 3:24 pmGDL-DSM
8h 24m1 stop
$545American Airlines
Find Deal
Wed, Sep 17 - Wed, Sep 24
American Airlines Logo
5:12 am - 9:38 amDSM-GDL
5h 26m1 stop
American Airlines Logo
6:00 am - 5:35 pmGDL-DSM
10h 35m1 stop
$549American Airlines
Find Deal
Fri, Aug 22 - Wed, Sep 3
Delta Logo
7:00 am - 6:33 pmDSM-GDL
12h 33m2 stops
Delta Logo
12:46 pm - 10:43 pmGDL-DSM
8h 57m1 stop
$574Delta
Find Deal
Fri, Aug 22 - Wed, Sep 3
Delta Logo
7:00 am - 3:30 pmDSM-GDL
9h 30m2 stops
Delta Logo
12:46 pm - 10:43 pmGDL-DSM
8h 57m1 stop
$575Delta
Find Deal
Fri, Aug 22 - Wed, Sep 3
United Airlines Logo
1:10 pm - 9:34 pmDSM-GDL
9h 24m2 stops
United Airlines Logo
6:40 am - 5:14 pmGDL-DSM
9h 34m2 stops
$582United Airlines
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Tue, Sep 16 - Tue, Sep 23
United Airlines Logo
6:05 am - 9:35 pmDSM-GDL
16h 30m1 stop
United Airlines Logo
5:45 am - 2:19 pmGDL-DSM
32h 34m2 stops
$666United Airlines
Find Deal
Thu, Oct 30 - Sat, Nov 8

Delta flights from Des Moines to Guadalajara

Our best Delta deals on Des Moines to Guadalajara flight tickets
Delta
Aug 22
DSM7:00 amDes Moines
12h 33m
2 stops
GDL6:33 pmGuadalajara Miguel Hidal
Sep 3
GDL12:46 pmGuadalajara Miguel Hidal
8h 57m
1 stop
DSM10:43 pmDes Moines
$574
Find similar
Delta
Aug 22
DSM7:00 amDes Moines
9h 30m
2 stops
GDL3:30 pmGuadalajara Miguel Hidal
Sep 3
GDL12:46 pmGuadalajara Miguel Hidal
8h 57m
1 stop
DSM10:43 pmDes Moines
$575
Find similar
Delta
Aug 21
DSM7:00 amDes Moines
10h 37m
2 stops
GDL4:37 pmGuadalajara Miguel Hidal
Sep 1
GDL12:46 pmGuadalajara Miguel Hidal
8h 57m
1 stop
DSM10:43 pmDes Moines
$655
Find similar

American Airlines flights from Des Moines to Guadalajara

Our best American Airlines deals on Des Moines to Guadalajara flight tickets
American Airlines
Sep 17
DSM4:09 pmDes Moines
8h 15m
1 stop
GDL11:24 pmGuadalajara Miguel Hidal
Sep 24
GDL6:00 amGuadalajara Miguel Hidal
8h 24m
1 stop
DSM3:24 pmDes Moines
$545
Find similar
American Airlines
Aug 22
DSM5:12 amDes Moines
5h 26m
1 stop
GDL9:38 amGuadalajara Miguel Hidal
Sep 3
GDL6:00 amGuadalajara Miguel Hidal
10h 35m
1 stop
DSM5:35 pmDes Moines
$549
Find similar
American Airlines
Sep 16
DSM4:09 pmDes Moines
8h 15m
1 stop
GDL11:24 pmGuadalajara Miguel Hidal
Sep 23
GDL1:25 pmGuadalajara Miguel Hidal
18h 39m
2 stops
DSM9:04 amDes Moines
$550
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Guadalajara that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 2, 2025.
Use the filters below to find and compare flights from Des Moines to Guadalajara that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Thu 9/4

8:00 am-8:15 pm

2 stops13h 15m

Guadalajara Miguel Hidal

Fri 9/5

8:54 am-10:29 pm

1 stop12h 35m

$440

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Thu 9/4

7:00 am-5:03 am

1 stop23h 03m

Guadalajara Miguel Hidal

Fri 9/5

10:20 am-10:29 pm

1 stop11h 09m

$458

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 9/14

2:25 pm-1:24 pm

2 stops23h 59m

Guadalajara Miguel Hidal

Sun 9/21

7:08 am-1:40 pm

2 stops29h 32m

$508

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 10/17

8:44 pm-10:23 pm

2 stops26h 39m

Guadalajara Miguel Hidal

Sun 10/26

3:18 pm-7:59 pm

2 stops27h 41m

$529

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Wed 9/17

4:09 pm-11:24 pm

1 stop8h 15m

Guadalajara Miguel Hidal

Wed 9/24

6:00 am-3:24 pm

1 stop8h 24m

$545

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 8/22

5:12 am-9:38 am

1 stop5h 26m

Guadalajara Miguel Hidal

Wed 9/3

6:00 am-5:35 pm

1 stop10h 35m

$549

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 8/22

7:00 am-6:33 pm

2 stops12h 33m

Guadalajara Miguel Hidal

Wed 9/3

12:46 pm-10:43 pm

1 stop8h 57m

$574

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 8/22

7:00 am-3:30 pm

2 stops9h 30m

Guadalajara Miguel Hidal

Wed 9/3

12:46 pm-10:43 pm

1 stop8h 57m

$575

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Tue 9/16

1:10 pm-9:34 pm

2 stops9h 24m

Guadalajara Miguel Hidal

Tue 9/23

6:40 am-5:14 pm

2 stops9h 34m

$582

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Thu 10/30

6:05 am-9:35 pm

1 stop16h 30m

Guadalajara Miguel Hidal

Sat 11/8

5:45 am-2:19 pm

2 stops32h 34m

$666

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guadalajara from

How to get the cheapest flight ticket from Des Moines to Guadalajara

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Guadalajara?

What is the cheapest month to fly to Guadalajara?

The cheapest month to fly to Guadalajara from Des Moines is in September. Flight prices, which tend to average around $542, are often lower during this time because this is during the off-season. If you’re not able to fly to Guadalajara in September, then April is your next best option. Flight prices from Des Moines to Guadalajara during April average around $570.

What is the cheapest day to depart on your flight to Guadalajara?

Our data shows that Saturday is the least expensive day to fly to Guadalajara. Tickets to fly out on this day can be as low as $574. Flights from Des Moines to Guadalajara on a Friday will generally be more expensive and average around $773. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Guadalajara?

Flying to Guadalajara from Des Moines in the morning is the least expensive time of day to depart. momondo users have found prices as low as $605 when looking at flights departing in the morning. In contrast, the most expensive time of day to depart to Guadalajara is in the evening when prices are around $829.

How have Des Moines to Guadalajara flight prices changed over time?

When to book flights from Des Moines to Guadalajara

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Guadalajara according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Guadalajara (DSM to GDL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Guadalajara

Best Price Found

$203

Fastest flight time

5h 26m

Direct flights

None

Airports in Guadalajara

1 airport
The best one-way flight to Guadalajara from Des Moines in the past 72 hours is $203. The best round-trip flight deal from Des Moines to Guadalajara found on momondo in the last 72 hours is $440.
The fastest flight from Des Moines to Guadalajara takes 5h 26m
There are no direct flights from Des Moines to Guadalajara. Popular non-direct route for this connection is Des Moines Airport - Guadalajara Miguel Hidal Airport.
There is 1 airport near Guadalajara: Guadalajara Miguel Hidal (GDL)
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  • How far is Des Moines to Guadalajara Miguel Hidal by plane?

    The distance between Des Moines and Guadalajara Miguel Hidal is about 1552.3 mi. In terms of flight time, this usually takes a little over 5h 26m.

  • When did momondo last update prices for flights from Des Moines Airport to Guadalajara Miguel Hidal Airport?

    Prices for flights from Des Moines Airport to Guadalajara Miguel Hidal Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Guadalajara Miguel Hidal Airport?

  • How old do you have to be to fly from Des Moines Airport to Guadalajara Miguel Hidal Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Guadalajara Miguel Hidal Airport.

  • What documentation or ID do you need to fly to Guadalajara Miguel Hidal Airport?

    The travel and health documents required for your trip to Guadalajara Miguel Hidal Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guadalajara Miguel Hidal Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Guadalajara?

Best airlines flying from Des Moines to Guadalajara

Compare and see reviews for airlines that fly from Des Moines to Guadalajara with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $502Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $521Free CancellationRating
7.4
8,904 reviews
Search United Airlines flights

Traveling to a place near Guadalajara?

Book flights to Guadalajara if you plan to visit one of these locations
Tequila
Ajijic
Zapopan
Tlaquepaque

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Guadalajara?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Guadalajara for you.

Can I find flights from Des Moines to Guadalajara with flexible booking policies on momondo?

Yes. All flights to Guadalajara from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Guadalajara?

Once all potential Des Moines to Guadalajara flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Guadalajara right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guadalajara, momondo offers a useful price alert feature which will track prices for flights to Guadalajara from Des Moines and alert you when they change.

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