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Cheap flights from Des Moines to Guadalajara from $212

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Guadalajara departing on 11/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Des Moines to Guadalajara

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
8:30 am - 6:25 pmDSM-GDL
9h 55m1 stop
Multiple Airlines Logo
6:08 am - 3:03 pmGDL-DSM
32h 55m2 stops
$436Multiple Airlines
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Thu, Jan 22 - Sat, Feb 7
Multiple Airlines Logo
8:30 am - 8:35 pmDSM-GDL
12h 05m1 stop
Multiple Airlines Logo
6:08 am - 3:03 pmGDL-DSM
32h 55m2 stops
$460Multiple Airlines
Find Deal
Fri, Jan 23 - Sat, Feb 7
United Airlines Logo
8:15 am - 10:35 pmDSM-GDL
14h 20m1 stop
United Airlines Logo
8:00 am - 2:12 pmGDL-DSM
6h 12m1 stop
$546United Airlines
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Thu, Dec 11 - Mon, Dec 15
United Airlines Logo
3:04 pm - 10:35 pmDSM-GDL
7h 31m1 stop
United Airlines Logo
2:30 pm - 10:30 pmGDL-DSM
7h 00m1 stop
$551United Airlines
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Mon, Feb 9 - Thu, May 7
American Airlines Logo
4:00 pm - 11:59 pmDSM-GDL
7h 59m1 stop
American Airlines Logo
4:44 pm - 11:23 pmGDL-DSM
6h 39m1 stop
$571American Airlines
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Fri, Jan 16 - Mon, Jan 19
Frontier Logo
7:58 pm - 1:17 pmDSM-GDL
17h 19m2 stops
Frontier Logo
7:04 am - 10:19 amGDL-DSM
27h 15m2 stops
$573Frontier
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Mon, Dec 8 - Mon, Dec 22
American Airlines Logo
11:35 am - 11:59 pmDSM-GDL
12h 24m1 stop
American Airlines Logo
4:44 pm - 11:23 pmGDL-DSM
6h 39m1 stop
$576American Airlines
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Fri, Jan 23 - Sun, Feb 8
Frontier Logo
8:19 pm - 5:41 pmDSM-GDL
21h 22m2 stops
Frontier Logo
3:18 pm - 7:03 pmGDL-DSM
27h 45m2 stops
$583Frontier
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Sun, Nov 30 - Sun, Dec 7
Aeromexico Logo
5:34 am - 12:27 amDSM-GDL
18h 53m2 stops
Aeromexico Logo
9:20 pm - 10:24 pmGDL-DSM
24h 04m2 stops
$587Aeromexico
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Mon, Feb 9 - Thu, May 7
Aeromexico Logo
5:34 am - 12:22 amDSM-GDL
18h 48m2 stops
Aeromexico Logo
2:06 pm - 10:34 pmGDL-DSM
8h 28m1 stop
$724Aeromexico
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Tue, Dec 9 - Wed, Dec 10

United Airlines flights from Des Moines to Guadalajara

Our best United Airlines deals on Des Moines to Guadalajara flight tickets
United Airlines
Dec 11
DSM8:15 amDes Moines
14h 20m
1 stop
GDL10:35 pmGuadalajara Miguel Hidal
Dec 15
GDL8:00 amGuadalajara Miguel Hidal
6h 12m
1 stop
DSM2:12 pmDes Moines
$546
Find similar
United Airlines
Feb 9
DSM3:04 pmDes Moines
7h 31m
1 stop
GDL10:35 pmGuadalajara Miguel Hidal
May 7
GDL2:30 pmGuadalajara Miguel Hidal
7h 00m
1 stop
DSM10:30 pmDes Moines
$551
Find similar
United Airlines
Feb 9
DSM8:00 amDes Moines
14h 35m
2 stops
GDL10:35 pmGuadalajara Miguel Hidal
May 7
GDL2:30 pmGuadalajara Miguel Hidal
7h 00m
1 stop
DSM10:30 pmDes Moines
$556
Find similar

American Airlines flights from Des Moines to Guadalajara

Our best American Airlines deals on Des Moines to Guadalajara flight tickets
American Airlines
Jan 16
DSM4:00 pmDes Moines
7h 59m
1 stop
GDL11:59 pmGuadalajara Miguel Hidal
Jan 19
GDL4:44 pmGuadalajara Miguel Hidal
6h 39m
1 stop
DSM11:23 pmDes Moines
$571
Find similar
American Airlines
Jan 23
DSM11:35 amDes Moines
12h 24m
1 stop
GDL11:59 pmGuadalajara Miguel Hidal
Feb 8
GDL4:44 pmGuadalajara Miguel Hidal
6h 39m
1 stop
DSM11:23 pmDes Moines
$576
Find similar
American Airlines
Nov 30
DSM5:00 amDes Moines
10h 09m
1 stop
GDL3:09 pmGuadalajara Miguel Hidal
Dec 7
GDL4:09 pmGuadalajara Miguel Hidal
6h 39m
1 stop
DSM10:48 pmDes Moines
$591
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Guadalajara that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Des Moines to Guadalajara that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Thu 1/22

8:30 am-6:25 pm

1 stop9h 55m

Guadalajara Miguel Hidal

Sat 2/7

6:08 am-3:03 pm

2 stops32h 55m

$436

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 1/23

8:30 am-8:35 pm

1 stop12h 05m

Guadalajara Miguel Hidal

Sat 2/7

6:08 am-3:03 pm

2 stops32h 55m

$460

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Thu 12/11

8:15 am-10:35 pm

1 stop14h 20m

Guadalajara Miguel Hidal

Mon 12/15

8:00 am-2:12 pm

1 stop6h 12m

$546

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Mon 2/9

3:04 pm-10:35 pm

1 stop7h 31m

Guadalajara Miguel Hidal

Thu 5/7

2:30 pm-10:30 pm

1 stop7h 00m

$551

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 1/16

4:00 pm-11:59 pm

1 stop7h 59m

Guadalajara Miguel Hidal

Mon 1/19

4:44 pm-11:23 pm

1 stop6h 39m

$571

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Mon 12/8

7:58 pm-1:17 pm

2 stops17h 19m

Guadalajara Miguel Hidal

Mon 12/22

7:04 am-10:19 am

2 stops27h 15m

$573

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Fri 1/23

11:35 am-11:59 pm

1 stop12h 24m

Guadalajara Miguel Hidal

Sun 2/8

4:44 pm-11:23 pm

1 stop6h 39m

$576

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Sun 11/30

8:19 pm-5:41 pm

2 stops21h 22m

Guadalajara Miguel Hidal

Sun 12/7

3:18 pm-7:03 pm

2 stops27h 45m

$583

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Mon 2/9

5:34 am-12:27 am

2 stops18h 53m

Guadalajara Miguel Hidal

Thu 5/7

9:20 pm-10:24 pm

2 stops24h 04m

$587

Des MoinesGuadalajara

DSM - GDL

DSMGDL

Des Moines

Tue 12/9

5:34 am-12:22 am

2 stops18h 48m

Guadalajara Miguel Hidal

Wed 12/10

2:06 pm-10:34 pm

1 stop8h 28m

$724

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guadalajara from

How to get the cheapest flight ticket from Des Moines to Guadalajara

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Des Moines and Guadalajara?

What is the cheapest month to fly to Guadalajara?

The cheapest month to fly to Guadalajara from Des Moines is in February. Flight prices, which tend to average around $557, are often lower during this time because this is during the off-season. If you’re not able to fly to Guadalajara in February, then April is your next best option. Flight prices from Des Moines to Guadalajara during April average around $570.

What is the cheapest day to depart on your flight to Guadalajara?

Our data shows that Saturday is the least expensive day to fly to Guadalajara. Tickets to fly out on this day can be as low as $574. Flights from Des Moines to Guadalajara on a Friday will generally be more expensive and average around $773. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Guadalajara?

Flying to Guadalajara from Des Moines in the morning is the least expensive time of day to depart. momondo users have found prices as low as $605 when looking at flights departing in the morning. In contrast, the most expensive time of day to depart to Guadalajara is in the evening when prices are around $829.

How have Des Moines to Guadalajara flight prices changed over time?

When to book flights from Des Moines to Guadalajara

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Guadalajara according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Guadalajara (DSM to GDL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Guadalajara

Direct flights

None
There are no direct flights from Des Moines to Guadalajara. There are no popular flight routes from Des Moines to Guadalajara.
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  • How far is Des Moines to Guadalajara Miguel Hidal by plane?

    The distance between Des Moines and Guadalajara Miguel Hidal is about 1552.3 mi. In terms of flight time, this usually takes a little over 6h 25m.

  • When did momondo last update prices for flights from Des Moines Airport to Guadalajara Miguel Hidal Airport?

    Prices for flights from Des Moines Airport to Guadalajara Miguel Hidal Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Des Moines Airport to Guadalajara Miguel Hidal Airport?

  • How old do you have to be to fly from Des Moines Airport to Guadalajara Miguel Hidal Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Guadalajara Miguel Hidal Airport.

  • What documentation or ID do you need to fly to Guadalajara Miguel Hidal Airport?

    The travel and health documents required for your trip to Guadalajara Miguel Hidal Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Guadalajara Miguel Hidal Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Des Moines to Guadalajara?

Best airlines flying from Des Moines to Guadalajara

Compare and see reviews for airlines that fly from Des Moines to Guadalajara with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $518Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
United AirlinesPriceFrom $521Free CancellationRating
7.4
9,002 reviews
Search United Airlines flights

Traveling to a place near Guadalajara?

Book flights to Guadalajara if you plan to visit one of these locations
Tequila
Ajijic
Zapopan
Tlaquepaque

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Guadalajara?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Des Moines to Guadalajara for you.

Can I find flights from Des Moines to Guadalajara with flexible booking policies on momondo?

Yes. All flights to Guadalajara from Des Moines on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Des Moines to Guadalajara?

Once all potential Des Moines to Guadalajara flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Guadalajara right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guadalajara, momondo offers a useful price alert feature which will track prices for flights to Guadalajara from Des Moines and alert you when they change.

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