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Cheap flights from Des Moines to Florence from $463

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Florence departing on 8/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Des Moines to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
Lufthansa Logo
3:20 pm - 6:30 pm
DSM
-
FLR
20h 10m
2 stops
Lufthansa Logo
10:20 am - 5:28 pm
FLR
-
DSM
38h 08m
2 stops
$794Lufthansa
Wed, Aug 19 - Wed, Aug 26
Lufthansa Logo
3:20 pm - 6:30 pm
DSM
-
FLR
20h 10m
2 stops
Lufthansa Logo
6:30 am - 5:28 pm
FLR
-
DSM
17h 58m
2 stops
$803Lufthansa
Wed, Aug 19 - Wed, Aug 26
Lufthansa Logo
3:20 pm - 8:15 pm
DSM
-
FLR
21h 55m
2 stops
Lufthansa Logo
6:30 am - 5:18 pm
FLR
-
DSM
17h 48m
2 stops
$804Lufthansa
Tue, Aug 18 - Tue, Aug 25
Multiple Airlines Logo
5:56 pm - 2:25 pm
DSM
-
FLR
13h 29m
2 stops
Multiple Airlines Logo
11:20 am - 8:39 pm
FLR
-
DSM
16h 19m
2 stops
$805Multiple Airlines
Tue, Aug 18 - Tue, Aug 25
Multiple Airlines Logo
5:56 pm - 2:25 pm
DSM
-
FLR
13h 29m
2 stops
Multiple Airlines Logo
11:20 am - 8:39 pm
FLR
-
DSM
16h 19m
2 stops
$806Multiple Airlines
Tue, Aug 18 - Tue, Aug 25
Multiple Airlines Logo
5:30 pm - 2:25 pm
DSM
-
FLR
13h 55m
2 stops
Multiple Airlines Logo
6:30 am - 4:50 pm
FLR
-
DSM
17h 20m
2 stops
$808Multiple Airlines
Wed, Aug 19 - Wed, Aug 26
Delta Logo
2:45 pm - 5:15 pm
DSM
-
FLR
19h 30m
2 stops
Delta Logo
11:20 am - 8:39 pm
FLR
-
DSM
16h 19m
2 stops
$814Delta
Tue, Aug 18 - Tue, Aug 25
United Airlines Logo
6:00 am - 12:40 pm
DSM
-
FLR
23h 40m
3 stops
United Airlines Logo
6:30 am - 5:18 pm
FLR
-
DSM
17h 48m
2 stops
$816United Airlines
Tue, Aug 18 - Tue, Aug 25
Air Canada Logo
8:00 am - 9:40 am
DSM
-
FLR
18h 40m
3 stops
Air Canada Logo
6:30 am - 9:23 pm
FLR
-
DSM
21h 53m
3 stops
$830Air Canada
Wed, Aug 19 - Wed, Aug 26
Air Canada Logo
8:00 am - 9:40 am
DSM
-
FLR
18h 40m
3 stops
Air Canada Logo
6:30 am - 9:23 pm
FLR
-
DSM
21h 53m
3 stops
$832Air Canada
Wed, Aug 19 - Wed, Aug 26

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Lufthansa flights from Des Moines to Florence

Our best Lufthansa deals on Des Moines to Florence flight tickets
Lufthansa
Aug 19
DSM3:20 pmDes Moines
20h 10m
2 stops
FLR6:30 pmFlorence Peretola
Aug 26
FLR10:20 amFlorence Peretola
38h 08m
2 stops
DSM5:28 pmDes Moines
$794
Lufthansa
Aug 19
DSM3:20 pmDes Moines
20h 10m
2 stops
FLR6:30 pmFlorence Peretola
Aug 26
FLR6:30 amFlorence Peretola
17h 58m
2 stops
DSM5:28 pmDes Moines
$803
Lufthansa
Aug 18
DSM3:20 pmDes Moines
21h 55m
2 stops
FLR8:15 pmFlorence Peretola
Aug 25
FLR6:30 amFlorence Peretola
17h 48m
2 stops
DSM5:18 pmDes Moines
$804

United Airlines flights from Des Moines to Florence

Our best United Airlines deals on Des Moines to Florence flight tickets
United Airlines
Aug 18
DSM6:00 amDes Moines
23h 40m
3 stops
FLR12:40 pmFlorence Peretola
Aug 25
FLR6:30 amFlorence Peretola
17h 48m
2 stops
DSM5:18 pmDes Moines
$816
United Airlines
Aug 20
DSM5:21 pmDes Moines
16h 14m
2 stops
FLR4:35 pmFlorence Peretola
Aug 27
FLR8:15 amFlorence Peretola
16h 13m
2 stops
DSM5:28 pmDes Moines
$859
United Airlines
Aug 21
DSM6:00 amDes Moines
22h 30m
3 stops
FLR11:30 amFlorence Peretola
Aug 28
FLR6:30 amFlorence Peretola
21h 53m
2 stops
DSM9:23 pmDes Moines
$867

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 10, 2026.
Use the filters below to find and compare flights from Des Moines to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 8/19

3:20 pm-6:30 pm

2 stops20h 10m

Florence Peretola

Wed 8/26

10:20 am-5:28 pm

2 stops38h 08m

$794

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 8/19

3:20 pm-6:30 pm

2 stops20h 10m

Florence Peretola

Wed 8/26

6:30 am-5:28 pm

2 stops17h 58m

$803

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 8/18

3:20 pm-8:15 pm

2 stops21h 55m

Florence Peretola

Tue 8/25

6:30 am-5:18 pm

2 stops17h 48m

$804
Quickest round-trip

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 8/18

5:56 pm-2:25 pm

2 stops13h 29m

Florence Peretola

Tue 8/25

11:20 am-8:39 pm

2 stops16h 19m

$805

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 8/18

5:56 pm-2:25 pm

2 stops13h 29m

Florence Peretola

Tue 8/25

11:20 am-8:39 pm

2 stops16h 19m

$806

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 8/19

5:30 pm-2:25 pm

2 stops13h 55m

Florence Peretola

Wed 8/26

6:30 am-4:50 pm

2 stops17h 20m

$808

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 8/18

2:45 pm-5:15 pm

2 stops19h 30m

Florence Peretola

Tue 8/25

11:20 am-8:39 pm

2 stops16h 19m

$814

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 8/18

6:00 am-12:40 pm

3 stops23h 40m

Florence Peretola

Tue 8/25

6:30 am-5:18 pm

2 stops17h 48m

$816

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 8/19

8:00 am-9:40 am

3 stops18h 40m

Florence Peretola

Wed 8/26

6:30 am-9:23 pm

3 stops21h 53m

$830

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 8/19

8:00 am-9:40 am

3 stops18h 40m

Florence Peretola

Wed 8/26

6:30 am-9:23 pm

3 stops21h 53m

$832

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Des Moines to Florence

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Florence?

If you aren’t able to travel during the month of February, then book flights to Florence from Des Moines during November instead. Flights to Florence in November, while not as cheap as those in February, still average around $780.

When to book flights from Des Moines to Florence

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Florence according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Florence (DSM to FLR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Florence

Fastest flight time

13h 55m

Direct flights

None
The fastest flight from Des Moines to Florence takes 13h 55m
There are no direct flights from Des Moines to Florence. There are no popular flight routes from Des Moines to Florence.
Search flight deals

Frequently asked questions about flying from Des Moines to Florence

  • How far is Des Moines to Florence Peretola by plane?

    The straight-line distance from Des Moines to Florence Peretola is 4923.7 mi. In terms of flight time, this usually takes a little over 13h 55m.

  • When did momondo last update prices for flights from Des Moines Airport to Florence Peretola Airport?

    Prices for flights from Des Moines Airport to Florence Peretola Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Florence Peretola Airport?

  • How old do you have to be to fly from Des Moines Airport to Florence Peretola Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Florence Peretola Airport.

  • What documentation or ID do you need to fly to Florence Peretola Airport?

    The necessary travel and health documents for your Florence Peretola Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Florence?

Best airlines flying from Des Moines to Florence

Compare and see reviews for airlines that fly from Des Moines to Florence with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $502Free CancellationRating
7.4
9,966 reviews
Search United Airlines flights
DeltaPriceFrom $701Free CancellationRating
7.8
8,456 reviews
Search Delta flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Prato
Siena
San Gimignano
Montecatini Terme
Fiesole
Pistoia
Arezzo
Colle di Val d'Elsa
Monteriggioni
Greve in Chianti
Impruneta
Volterra
Poggibonsi

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Florence with flexible booking policies on momondo?

Flights from Des Moines to Florence with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Florence?

Once all potential Des Moines to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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