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Cheap flights from Des Moines to Florence from $771

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Florence departing on 8/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from Des Moines to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
Lufthansa Logo
6:50 pm - 8:15 pm
DSM
-
FLR
18h 25m
2 stops
Lufthansa Logo
6:30 am - 9:12 pm
FLR
-
DSM
21h 42m
2 stops
$771Lufthansa
Mon, Aug 17 - Thu, Aug 27
Multiple Airlines Logo
5:35 pm - 2:25 pm
DSM
-
FLR
13h 50m
2 stops
Multiple Airlines Logo
6:30 am - 2:07 pm
FLR
-
DSM
14h 37m
2 stops
$815Multiple Airlines
Sun, Aug 16 - Wed, Aug 26
Lufthansa Logo
7:16 pm - 8:15 pm
DSM
-
FLR
17h 59m
2 stops
Lufthansa Logo
6:30 am - 11:17 pm
FLR
-
DSM
23h 47m
2 stops
$908Lufthansa
Wed, Apr 15 - Wed, Apr 22
Lufthansa Logo
7:16 pm - 8:15 pm
DSM
-
FLR
17h 59m
2 stops
Lufthansa Logo
6:30 am - 9:32 pm
FLR
-
DSM
22h 02m
2 stops
$909Lufthansa
Wed, Apr 15 - Wed, Apr 22
Lufthansa Logo
7:16 pm - 6:30 pm
DSM
-
FLR
16h 14m
2 stops
Lufthansa Logo
6:30 am - 11:17 pm
FLR
-
DSM
23h 47m
2 stops
$919Lufthansa
Wed, Apr 15 - Wed, Apr 22
Multiple Airlines Logo
5:56 pm - 4:50 pm
DSM
-
FLR
15h 54m
2 stops
Multiple Airlines Logo
11:25 am - 9:03 pm
FLR
-
DSM
16h 38m
2 stops
$958Multiple Airlines
Tue, May 12 - Tue, May 19
KLM Logo
5:28 pm - 10:30 pm
DSM
-
FLR
46h 02m
2 stops
KLM Logo
7:40 pm - 4:48 pm
FLR
-
DSM
28h 08m
2 stops
$963KLM
Tue, May 12 - Tue, May 19
KLM Logo
2:33 pm - 7:00 pm
DSM
-
FLR
21h 27m
2 stops
KLM Logo
7:40 pm - 4:48 pm
FLR
-
DSM
28h 08m
2 stops
$964KLM
Mon, May 11 - Mon, May 18
KLM Logo
5:56 pm - 4:50 pm
DSM
-
FLR
15h 54m
2 stops
KLM Logo
6:30 am - 4:48 pm
FLR
-
DSM
17h 18m
2 stops
$965KLM
Tue, May 12 - Tue, May 19
Multiple Airlines Logo
5:56 pm - 4:50 pm
DSM
-
FLR
15h 54m
2 stops
Multiple Airlines Logo
11:25 am - 9:03 pm
FLR
-
DSM
16h 38m
2 stops
$969Multiple Airlines
Tue, May 12 - Tue, May 19

KLM flights from Des Moines to Florence

Our best KLM deals on Des Moines to Florence flight tickets
KLM
May 12
DSM5:28 pmDes Moines
46h 02m
2 stops
FLR10:30 pmFlorence Peretola
May 19
FLR7:40 pmFlorence Peretola
28h 08m
2 stops
DSM4:48 pmDes Moines
$963
KLM
May 11
DSM2:33 pmDes Moines
21h 27m
2 stops
FLR7:00 pmFlorence Peretola
May 18
FLR7:40 pmFlorence Peretola
28h 08m
2 stops
DSM4:48 pmDes Moines
$964
KLM
May 12
DSM5:56 pmDes Moines
15h 54m
2 stops
FLR4:50 pmFlorence Peretola
May 19
FLR6:30 amFlorence Peretola
17h 18m
2 stops
DSM4:48 pmDes Moines
$965

Air Canada flights from Des Moines to Florence

Our best Air Canada deals on Des Moines to Florence flight tickets
Air Canada
Apr 15
DSM6:20 amDes Moines
20h 20m
3 stops
FLR9:40 amFlorence Peretola
Apr 22
FLR8:15 amFlorence Peretola
20h 17m
3 stops
DSM9:32 pmDes Moines
$1,070
Air Canada
May 12
DSM8:00 amDes Moines
18h 40m
3 stops
FLR9:40 amFlorence Peretola
May 19
FLR6:30 amFlorence Peretola
21h 53m
3 stops
DSM9:23 pmDes Moines
$1,376
Air Canada
Aug 17
DSM8:00 amDes Moines
21h 50m
3 stops
FLR12:50 pmFlorence Peretola
Aug 27
FLR6:30 amFlorence Peretola
19h 54m
3 stops
DSM7:24 pmDes Moines
$1,532

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Des Moines to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Mon 8/17

6:50 pm-8:15 pm

2 stops18h 25m

Florence Peretola

Thu 8/27

6:30 am-9:12 pm

2 stops21h 42m

$771
Quickest round-trip

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sun 8/16

5:35 pm-2:25 pm

2 stops13h 50m

Florence Peretola

Wed 8/26

6:30 am-2:07 pm

2 stops14h 37m

$815

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 4/15

7:16 pm-8:15 pm

2 stops17h 59m

Florence Peretola

Wed 4/22

6:30 am-11:17 pm

2 stops23h 47m

$908

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 4/15

7:16 pm-8:15 pm

2 stops17h 59m

Florence Peretola

Wed 4/22

6:30 am-9:32 pm

2 stops22h 02m

$909

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 4/15

7:16 pm-6:30 pm

2 stops16h 14m

Florence Peretola

Wed 4/22

6:30 am-11:17 pm

2 stops23h 47m

$919

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 5/12

5:56 pm-4:50 pm

2 stops15h 54m

Florence Peretola

Tue 5/19

11:25 am-9:03 pm

2 stops16h 38m

$958

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 5/12

5:28 pm-10:30 pm

2 stops46h 02m

Florence Peretola

Tue 5/19

7:40 pm-4:48 pm

2 stops28h 08m

$963

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Mon 5/11

2:33 pm-7:00 pm

2 stops21h 27m

Florence Peretola

Mon 5/18

7:40 pm-4:48 pm

2 stops28h 08m

$964

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 5/12

5:56 pm-4:50 pm

2 stops15h 54m

Florence Peretola

Tue 5/19

6:30 am-4:48 pm

2 stops17h 18m

$965

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 5/12

5:56 pm-4:50 pm

2 stops15h 54m

Florence Peretola

Tue 5/19

11:25 am-9:03 pm

2 stops16h 38m

$969

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Des Moines to Florence

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Des Moines to Florence Peretola?

British Airways and United Airlines are the most popular carriers operating from Des Moines to Florence Peretola

When to book flights from Des Moines to Florence

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Florence according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Florence (DSM to FLR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Florence

Fastest flight time

17h 59m

Direct flights

None
The fastest flight from Des Moines to Florence takes 17h 59m
There are no direct flights from Des Moines to Florence. There are no popular flight routes from Des Moines to Florence.
Search flight deals

Frequently asked questions about flying from Des Moines to Florence

  • How far is Des Moines to Florence Peretola by plane?

    The straight-line distance from Des Moines to Florence Peretola is 4923.7 mi. In terms of flight time, this usually takes a little over 17h 59m.

  • When did momondo last update prices for flights from Des Moines Airport to Florence Peretola Airport?

    Prices for flights from Des Moines Airport to Florence Peretola Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Florence Peretola Airport?

  • How old do you have to be to fly from Des Moines Airport to Florence Peretola Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Florence Peretola Airport.

  • What documentation or ID do you need to fly to Florence Peretola Airport?

    The necessary travel and health documents for your Florence Peretola Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Florence?

Best airlines flying from Des Moines to Florence

Compare and see reviews for airlines that fly from Des Moines to Florence with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $502Free CancellationRating
7.4
9,529 reviews
Search United Airlines flights
DeltaPriceFrom $505Free CancellationRating
7.9
8,368 reviews
Search Delta flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Prato
Siena
San Gimignano
Montecatini Terme
Arezzo
Pistoia
Colle di Val d'Elsa
Fiesole
Greve in Chianti
Impruneta
Monteriggioni
Volterra
Poggibonsi

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Florence with flexible booking policies on momondo?

Flights from Des Moines to Florence with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Florence?

Once all potential Des Moines to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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