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Cheap flights from Des Moines to Florence from $462

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Des Moines to Florence departing on 2/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Des Moines to Florence

Cheap round-trip flights

Enter your travel dates to find the best prices.
Lufthansa Logo
6:48 pm - 10:00 pm
DSM
-
FLR
20h 12m2 stops
Lufthansa Logo
6:30 am - 5:47 pm
FLR
-
DSM
18h 17m2 stops
$462Lufthansa
화, 2월 3 - 화, 2월 10
Lufthansa Logo
6:48 pm - 4:30 pm
DSM
-
FLR
14h 42m2 stops
Lufthansa Logo
6:30 am - 9:41 pm
FLR
-
DSM
22h 11m2 stops
$480Lufthansa
화, 2월 10 - 화, 2월 24
Multiple Airlines Logo
6:48 pm - 10:00 pm
DSM
-
FLR
20h 12m3 stops
Multiple Airlines Logo
6:30 am - 10:30 pm
FLR
-
DSM
23h 00m2 stops
$481Multiple Airlines
일, 2월 1 - 일, 2월 8
Multiple Airlines Logo
3:35 pm - 1:35 pm
DSM
-
FLR
15h 00m2 stops
Multiple Airlines Logo
6:30 am - 10:30 pm
FLR
-
DSM
23h 00m2 stops
$482Multiple Airlines
일, 2월 1 - 일, 2월 8
Multiple Airlines Logo
11:26 am - 2:25 pm
DSM
-
FLR
19h 59m2 stops
Multiple Airlines Logo
6:40 am - 9:24 pm
FLR
-
DSM
21h 44m2 stops
$487Multiple Airlines
화, 2월 3 - 화, 2월 10
Multiple Airlines Logo
5:16 pm - 7:50 pm
DSM
-
FLR
19h 34m2 stops
Multiple Airlines Logo
6:40 am - 8:54 pm
FLR
-
DSM
21h 14m2 stops
$488Multiple Airlines
월, 2월 2 - 월, 2월 9
Multiple Airlines Logo
12:06 pm - 2:25 pm
DSM
-
FLR
19h 19m2 stops
Multiple Airlines Logo
6:40 am - 8:54 pm
FLR
-
DSM
21h 14m2 stops
$490Multiple Airlines
화, 2월 3 - 화, 2월 10
Multiple Airlines Logo
11:26 am - 2:25 pm
DSM
-
FLR
19h 59m2 stops
Multiple Airlines Logo
6:40 am - 8:54 pm
FLR
-
DSM
21h 14m2 stops
$491Multiple Airlines
화, 2월 3 - 화, 2월 10
Lufthansa Logo
11:30 am - 12:35 pm
DSM
-
FLR
18h 05m2 stops
Lufthansa Logo
1:15 pm - 9:50 pm
FLR
-
DSM
15h 35m2 stops
$493Lufthansa
월, 2월 2 - 월, 2월 9
KLM Logo
10:59 am - 11:35 am
DSM
-
FLR
17h 36m2 stops
KLM Logo
6:40 am - 8:54 pm
FLR
-
DSM
21h 14m2 stops
$496KLM
월, 2월 2 - 월, 2월 9

Lufthansa flights from Des Moines to Florence

Our best Lufthansa deals on Des Moines to Florence flight tickets
Lufthansa
Feb 3
DSM6:48 pmDes Moines
20h 12m
2 stops
FLR10:00 pmFlorence Peretola
Feb 10
FLR6:30 amFlorence Peretola
18h 17m
2 stops
DSM5:47 pmDes Moines
$462
Find similar
Lufthansa
Feb 10
DSM6:48 pmDes Moines
14h 42m
2 stops
FLR4:30 pmFlorence Peretola
Feb 24
FLR6:30 amFlorence Peretola
22h 11m
2 stops
DSM9:41 pmDes Moines
$480
Find similar
Lufthansa
Feb 2
DSM11:30 amDes Moines
18h 05m
2 stops
FLR12:35 pmFlorence Peretola
Feb 9
FLR1:15 pmFlorence Peretola
15h 35m
2 stops
DSM9:50 pmDes Moines
$493
Find similar

KLM flights from Des Moines to Florence

Our best KLM deals on Des Moines to Florence flight tickets
KLM
Feb 2
DSM10:59 amDes Moines
17h 36m
2 stops
FLR11:35 amFlorence Peretola
Feb 9
FLR6:40 amFlorence Peretola
21h 14m
2 stops
DSM8:54 pmDes Moines
$496
Find similar
KLM
Feb 2
DSM5:16 pmDes Moines
16h 04m
2 stops
FLR4:20 pmFlorence Peretola
Feb 9
FLR6:40 amFlorence Peretola
16h 01m
2 stops
DSM3:41 pmDes Moines
$497
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Des Moines to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated 12월 20, 2025.
Use the filters below to find and compare flights from Des Moines to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

화 2/3

6:48 pm-10:00 pm

2 stops20h 12m

Florence Peretola

화 2/10

6:30 am-5:47 pm

2 stops18h 17m

$462

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

화 2/10

6:48 pm-4:30 pm

2 stops14h 42m

Florence Peretola

화 2/24

6:30 am-9:41 pm

2 stops22h 11m

$480

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

일 2/1

6:48 pm-10:00 pm

3 stops20h 12m

Florence Peretola

일 2/8

6:30 am-10:30 pm

2 stops23h 00m

$481

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

일 2/1

3:35 pm-1:35 pm

2 stops15h 00m

Florence Peretola

일 2/8

6:30 am-10:30 pm

2 stops23h 00m

$482

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

화 2/3

11:26 am-2:25 pm

2 stops19h 59m

Florence Peretola

화 2/10

6:40 am-9:24 pm

2 stops21h 44m

$487

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

월 2/2

5:16 pm-7:50 pm

2 stops19h 34m

Florence Peretola

월 2/9

6:40 am-8:54 pm

2 stops21h 14m

$488

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

화 2/3

12:06 pm-2:25 pm

2 stops19h 19m

Florence Peretola

화 2/10

6:40 am-8:54 pm

2 stops21h 14m

$490

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

화 2/3

11:26 am-2:25 pm

2 stops19h 59m

Florence Peretola

화 2/10

6:40 am-8:54 pm

2 stops21h 14m

$491

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

월 2/2

11:30 am-12:35 pm

2 stops18h 05m

Florence Peretola

월 2/9

1:15 pm-9:50 pm

2 stops15h 35m

$493

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

월 2/2

10:59 am-11:35 am

2 stops17h 36m

Florence Peretola

월 2/9

6:40 am-8:54 pm

2 stops21h 14m

$496

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first
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See travel insights to Florence from

How to get the cheapest flight ticket from Des Moines to Florence

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Florence?

On average, the least expensive day to fly to Florence from Des Moines is on a Tuesday. momondo users have found tickets for Tuesday departures for as low as $1,244. However, this price may fluctuate depending on the airline, the season, and holidays. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Florence on Thursday is $1,991.

What is the cheapest time of day to depart on your flight to Florence?

Our data shows that the cheapest Des Moines to Florence flights are usually those with departure times in the afternoon. Our users have found flights to Florence in the afternoon for as low as $1,238. Flights to Florence are more costly in the morning, with an average ticket price of $1,785. Departure times in the morning fall within the peak daily travel times, which is why tickets can be more expensive.

When to book flights from Des Moines to Florence

Are you open to changing your travel dates? Check out the ideal times to fly from Des Moines to Florence according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Des Moines to Florence (DSM to FLR) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Des Moines to Florence

Fastest flight time

14h 04m

Direct flights

None
The fastest flight from Des Moines to Florence takes 14h 04m
There are no direct flights from Des Moines to Florence. There are no popular flight routes from Des Moines to Florence.
Search flight deals

  • How far is Des Moines to Florence Peretola by plane?

    The straight-line distance from Des Moines to Florence Peretola is 4923.7 mi. In terms of flight time, this usually takes a little over 14h 04m.

  • When did momondo last update prices for flights from Des Moines Airport to Florence Peretola Airport?

    Prices for flights from Des Moines Airport to Florence Peretola Airport refresh daily.

  • How many operators does momondo search for flights from Des Moines Airport to Florence Peretola Airport?

  • How old do you have to be to fly from Des Moines Airport to Florence Peretola Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Des Moines Airport to Florence Peretola Airport.

  • What documentation or ID do you need to fly to Florence Peretola Airport?

    The necessary travel and health documents for your Florence Peretola Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Des Moines to Florence?

Best airlines flying from Des Moines to Florence

Compare and see reviews for airlines that fly from Des Moines to Florence with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $660Free CancellationRating
7.9
8,021 reviews
Search Delta flights
United AirlinesPriceFrom $790Free CancellationRating
7.4
9,099 reviews
Search United Airlines flights

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Siena
Prato
San Gimignano
Montecatini Terme
Arezzo
Pistoia
Colle di Val d'Elsa
Fiesole
Impruneta
Greve in Chianti
Monteriggioni
Volterra

Why use momondo?

Why should I use momondo to find a flight deal from Des Moines to Florence?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Des Moines to Florence. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Des Moines to Florence with flexible booking policies on momondo?

Flights from Des Moines to Florence with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Des Moines to Florence?

Once all potential Des Moines to Florence flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Des Moines to Florence right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Des Moines to Florence flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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