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Cheap flights from Columbia to Chicago from $222

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Columbia to Chicago departing on 1/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Columbia to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
5:06 pm - 10:22 pm
CAE
-
MDW
6h 16m1 stop
Delta Logo
6:00 am - 11:58 am
MDW
-
CAE
4h 58m1 stop
$229Delta
Fri, Jan 23 - Sun, Jan 25
Delta Logo
6:59 pm - 10:22 pm
CAE
-
MDW
4h 23m1 stop
Delta Logo
6:00 am - 11:58 am
MDW
-
CAE
4h 58m1 stop
$254Delta
Fri, Jan 23 - Mon, Jan 26
Delta Logo
12:45 pm - 4:29 pm
CAE
-
MDW
4h 44m1 stop
Delta Logo
6:00 am - 11:58 am
MDW
-
CAE
4h 58m1 stop
$279Delta
Fri, Jan 16 - Mon, Jan 19
Delta Logo
12:45 pm - 4:29 pm
CAE
-
MDW
4h 44m1 stop
Delta Logo
6:45 am - 11:58 am
MDW
-
CAE
4h 13m1 stop
$314Delta
Fri, Jan 9 - Sat, Jan 10
Delta Logo
7:00 am - 9:55 am
CAE
-
MDW
3h 55m1 stop
Delta Logo
12:47 pm - 7:58 pm
MDW
-
CAE
6h 11m1 stop
$404Delta
Fri, Mar 20 - Sun, Mar 22
Delta Logo
12:45 pm - 4:29 pm
CAE
-
MDW
4h 44m1 stop
Delta Logo
6:45 am - 11:58 am
MDW
-
CAE
4h 13m1 stop
$429Delta
Mon, Jan 5 - Mon, Jan 12
Delta Logo
3:09 pm - 5:45 pm
CAE
-
MDW
3h 36m1 stop
Delta Logo
10:53 am - 4:21 pm
MDW
-
CAE
4h 28m1 stop
$443Delta
Tue, Mar 3 - Wed, Mar 4
Delta Logo
5:09 pm - 10:07 pm
CAE
-
MDW
5h 58m1 stop
Delta Logo
6:45 am - 2:17 pm
MDW
-
CAE
6h 32m1 stop
$465Delta
Tue, Jan 6 - Thu, Jan 8
Delta Logo
6:00 am - 9:05 am
CAE
-
MDW
4h 05m1 stop
Delta Logo
6:45 am - 11:58 am
MDW
-
CAE
4h 13m1 stop
$499Delta
Tue, Dec 30 - Mon, Jan 5
Delta Logo
6:00 am - 9:05 am
CAE
-
MDW
4h 05m1 stop
Delta Logo
6:00 am - 12:17 pm
MDW
-
CAE
5h 17m1 stop
$519Delta
Wed, Dec 31 - Thu, Jan 1

Delta flights from Columbia to Chicago Midway Airport

Our best Delta deals on Columbia to Chicago Midway Airport flight tickets
Delta
Jan 23
CAE5:06 pmColumbia Metropolitan
6h 16m
1 stop
MDW10:22 pmChicago Midway
Jan 25
MDW6:00 amChicago Midway
4h 58m
1 stop
CAE11:58 amColumbia Metropolitan
$229
Find similar
Delta
Jan 23
CAE6:59 pmColumbia Metropolitan
4h 23m
1 stop
MDW10:22 pmChicago Midway
Jan 26
MDW6:00 amChicago Midway
4h 58m
1 stop
CAE11:58 amColumbia Metropolitan
$254
Find similar
Delta
Jan 16
CAE12:45 pmColumbia Metropolitan
4h 44m
1 stop
MDW4:29 pmChicago Midway
Jan 19
MDW6:00 amChicago Midway
4h 58m
1 stop
CAE11:58 amColumbia Metropolitan
$279
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Columbia to Chicago Midway Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Columbia to Chicago Midway Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ColumbiaChicago

CAE - MDW

CAEMDW

Columbia Metropolitan

Fri 1/23

5:06 pm-10:22 pm

1 stop6h 16m

Chicago Midway

Sun 1/25

6:00 am-11:58 am

1 stop4h 58m

$229

ColumbiaChicago

CAE - MDW

CAEMDW

Columbia Metropolitan

Fri 1/23

6:59 pm-10:22 pm

1 stop4h 23m

Chicago Midway

Mon 1/26

6:00 am-11:58 am

1 stop4h 58m

$254

ColumbiaChicago

CAE - MDW

CAEMDW

Columbia Metropolitan

Fri 1/16

12:45 pm-4:29 pm

1 stop4h 44m

Chicago Midway

Mon 1/19

6:00 am-11:58 am

1 stop4h 58m

$279

ColumbiaChicago

CAE - MDW

CAEMDW

Columbia Metropolitan

Fri 1/9

12:45 pm-4:29 pm

1 stop4h 44m

Chicago Midway

Sat 1/10

6:45 am-11:58 am

1 stop4h 13m

$314

ColumbiaChicago

CAE - MDW

CAEMDW

Columbia Metropolitan

Fri 3/20

7:00 am-9:55 am

1 stop3h 55m

Chicago Midway

Sun 3/22

12:47 pm-7:58 pm

1 stop6h 11m

$404

ColumbiaChicago

CAE - MDW

CAEMDW

Columbia Metropolitan

Mon 1/5

12:45 pm-4:29 pm

1 stop4h 44m

Chicago Midway

Mon 1/12

6:45 am-11:58 am

1 stop4h 13m

$429

ColumbiaChicago

CAE - MDW

CAEMDW

Columbia Metropolitan

Tue 3/3

3:09 pm-5:45 pm

1 stop3h 36m

Chicago Midway

Wed 3/4

10:53 am-4:21 pm

1 stop4h 28m

$443

ColumbiaChicago

CAE - MDW

CAEMDW

Columbia Metropolitan

Tue 1/6

5:09 pm-10:07 pm

1 stop5h 58m

Chicago Midway

Thu 1/8

6:45 am-2:17 pm

1 stop6h 32m

$465

ColumbiaChicago

CAE - MDW

CAEMDW

Columbia Metropolitan

Tue 12/30

6:00 am-9:05 am

1 stop4h 05m

Chicago Midway

Mon 1/5

6:45 am-11:58 am

1 stop4h 13m

$499

ColumbiaChicago

CAE - MDW

CAEMDW

Columbia Metropolitan

Wed 12/31

6:00 am-9:05 am

1 stop4h 05m

Chicago Midway

Thu 1/1

6:00 am-12:17 pm

1 stop5h 17m

$519

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Columbia to Chicago Midway Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Chicago Midway Airport?

According to our data, Wednesday is the cheapest day to fly to Chicago Midway Airport from Columbia. The lowest ticket price found for a Wednesday departure recently was $315. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. On the other hand, Monday is the most expensive day to depart from Columbia because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $686.

What is the cheapest time of day to depart on your flight to Chicago Midway Airport?

Flying to Chicago Midway Airport from Columbia in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $371 when looking at flights departing in the afternoon. Try not to purchase tickets in the morning because they tend to be around $478. Of course, these prices can vary depending on the time of year and what airport you fly to.

When to book flights from Columbia to Chicago Midway Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Columbia to Chicago Midway Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Columbia to Chicago Midway Airport (CAE to MDW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Columbia to Chicago Midway Airport

Fastest flight time

3h 36m

Direct flights

None
The fastest flight from Columbia to Chicago Midway Airport takes 3h 36m
There are no direct flights from Columbia to Chicago Midway Airport. There are no popular flight routes from Columbia to Chicago Midway Airport.
Search flight deals

  • How far is Columbia Metropolitan to Chicago Midway by plane?

    The straight-line distance from Columbia Metropolitan to Chicago Midway is 649.7 mi. 3h 36m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Columbia Metropolitan Airport to Chicago Midway Airport?

    Prices for flights from Columbia Metropolitan Airport to Chicago Midway Airport are updated daily.

  • How many operators does momondo search for flights from Columbia Metropolitan Airport to Chicago Midway Airport?

  • How old do you have to be to fly from Columbia Metropolitan Airport to Chicago Midway Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Columbia Metropolitan Airport to Chicago Midway Airport.

  • What documentation or ID do you need to fly to Chicago Midway Airport?

    The travel and health documents required for your trip to Chicago Midway Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Chicago Midway Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Columbia to Chicago Midway Airport?

Best airlines flying from Columbia to Chicago Midway Airport

Compare and see reviews for airlines that fly from Columbia to Chicago Midway Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $266Free CancellationRating
7.9
8,008 reviews
Search Delta flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
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Porter
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Saint John

Why use momondo?

Why should I use momondo to find a flight deal from Columbia to Chicago?

It is quick and easy to find Columbia to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Columbia to Chicago with flexible booking policies on momondo?

All flight searches from Columbia to Chicago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Columbia to Chicago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Chicago from Columbia.

I’m not ready to book a flight from Columbia to Chicago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Columbia to Chicago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Chicago Midway Airport trip

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