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Cheap flights from Cleveland to Santiago de los Caballeros from $225

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Cleveland to Santiago de los Caballeros departing on 9/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Cleveland to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
6:00 am - 5:33 pmCLE  Cleveland Hopkins Intl-STI Santiago de los Caballeros
11h 33m1 stop New York LaGuardia
Delta Logo
7:05 pm - 10:51 amSTI  Santiago de los Caballeros-CLE Cleveland Hopkins Intl
15h 46m1 stop New York John F Kennedy Intl
$480Delta
Sun, Oct 11 - Tue, Oct 20
Delta Logo
6:00 am - 5:33 pmCLE  Cleveland Hopkins Intl-STI Santiago de los Caballeros
11h 33m1 stop New York LaGuardia
Delta Logo
7:05 pm - 10:51 amSTI  Santiago de los Caballeros-CLE Cleveland Hopkins Intl
15h 46m1 stop New York John F Kennedy Intl
$480Delta
Sun, Oct 11 - Fri, Oct 23
Delta Logo
6:00 am - 5:33 pmCLE  Cleveland Hopkins Intl-STI Santiago de los Caballeros
11h 33m1 stop New York LaGuardia
Delta Logo
7:05 pm - 10:51 amSTI  Santiago de los Caballeros-CLE Cleveland Hopkins Intl
15h 46m1 stop New York John F Kennedy Intl
$480Delta
Wed, Oct 14 - Thu, Oct 22
JetBlue Logo
8:00 am - 2:45 pmCLE  Cleveland Hopkins Intl-STI Santiago de los Caballeros
6h 45m1 stop Fort Lauderdale
JetBlue Logo
3:55 pm - 11:59 pmSTI  Santiago de los Caballeros-CLE Cleveland Hopkins Intl
8h 04m1 stop Fort Lauderdale
$556JetBlue
Fri, Oct 16 - Sat, Oct 17
JetBlue Logo
7:00 am - 1:27 pmCLE  Cleveland Hopkins Intl-STI Santiago de los Caballeros
6h 27m1 stop Fort Lauderdale
JetBlue Logo
3:15 pm - 10:54 pmSTI  Santiago de los Caballeros-CLE Cleveland Hopkins Intl
7h 39m1 stop New York John F Kennedy Intl
$556JetBlue
Tue, Oct 6 - Fri, Oct 9
JetBlue Logo
8:00 am - 2:45 pmCLE  Cleveland Hopkins Intl-STI Santiago de los Caballeros
6h 45m1 stop Fort Lauderdale
JetBlue Logo
3:55 pm - 11:59 pmSTI  Santiago de los Caballeros-CLE Cleveland Hopkins Intl
8h 04m1 stop Fort Lauderdale
$556JetBlue
Fri, Oct 16 - Thu, Oct 22
American Airlines Logo
6:19 am - 2:15 pmCLE  Cleveland Hopkins Intl-STI Santiago de los Caballeros
7h 56m1 stop Miami
American Airlines Logo
3:15 pm - 11:46 pmSTI  Santiago de los Caballeros-CLE Cleveland Hopkins Intl
8h 31m1 stop Miami
$567American Airlines
Sun, Sep 20 - Sat, Sep 26
American Airlines Logo
7:40 pm - 2:15 pmCLE  Cleveland Hopkins Intl-STI Santiago de los Caballeros
18h 35m2 stops Washington, D.C. Reagan-National Miami
American Airlines Logo
3:15 pm - 9:15 amSTI  Santiago de los Caballeros-CLE Cleveland Hopkins Intl
18h 00m2 stops Miami Chicago O'Hare Intl
$572American Airlines
Sun, Sep 20 - Sat, Sep 26
United Airlines Logo
8:05 am - 12:57 pmCLE  Cleveland Hopkins Intl-STI Santiago de los Caballeros
28h 52m1 stop Newark
United Airlines Logo
6:00 am - 9:59 pmSTI  Santiago de los Caballeros-CLE Cleveland Hopkins Intl
15h 59m1 stop Newark
$641United Airlines
Sun, Sep 20 - Sat, Sep 26
United Airlines Logo
8:05 am - 10:52 pmCLE  Cleveland Hopkins Intl-STI Santiago de los Caballeros
14h 47m1 stop Newark
United Airlines Logo
6:00 am - 9:51 pmSTI  Santiago de los Caballeros-CLE Cleveland Hopkins Intl
15h 51m1 stop Newark
$647United Airlines
Sun, Sep 6 - Wed, Sep 16

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American Airlines flights from Cleveland to Santiago de los Caballeros

Our best American Airlines deals on Cleveland to Santiago de los Caballeros flight tickets
American Airlines
Sep 20
CLE6:19 amCleveland Hopkins Intl
7h 56m
1 stop
STI2:15 pmSantiago de los Caballeros
Sep 26
STI3:15 pmSantiago de los Caballeros
8h 31m
1 stop
CLE11:46 pmCleveland Hopkins Intl
$567
American Airlines
Sep 20
CLE7:40 pmCleveland Hopkins Intl
18h 35m
2 stops
STI2:15 pmSantiago de los Caballeros
Sep 26
STI3:15 pmSantiago de los Caballeros
18h 00m
2 stops
CLE9:15 amCleveland Hopkins Intl
$572
American Airlines
Sep 20
CLE6:19 amCleveland Hopkins Intl
7h 56m
1 stop
STI2:15 pmSantiago de los Caballeros
Sep 26
STI3:15 pmSantiago de los Caballeros
19h 59m
2 stops
CLE11:14 amCleveland Hopkins Intl
$585

Delta flights from Cleveland to Santiago de los Caballeros

Our best Delta deals on Cleveland to Santiago de los Caballeros flight tickets
Delta
Oct 11
CLE6:00 amCleveland Hopkins Intl
11h 33m
1 stop
STI5:33 pmSantiago de los Caballeros
Oct 22
STI7:05 pmSantiago de los Caballeros
15h 46m
1 stop
CLE10:51 amCleveland Hopkins Intl
$480
Delta
Oct 15
CLE7:15 amCleveland Hopkins Intl
10h 18m
1 stop
STI5:33 pmSantiago de los Caballeros
Oct 20
STI7:05 pmSantiago de los Caballeros
17h 17m
1 stop
CLE12:22 pmCleveland Hopkins Intl
$482
Delta
Oct 15
CLE7:15 amCleveland Hopkins Intl
10h 18m
1 stop
STI5:33 pmSantiago de los Caballeros
Oct 19
STI7:05 pmSantiago de los Caballeros
17h 17m
1 stop
CLE12:22 pmCleveland Hopkins Intl
$484

momondo Fare Finder

 
Customize your flight search to find flights from Cleveland to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 18, 2026.
Use the filters below to find and compare flights from Cleveland to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ClevelandSantiago de los Caballeros

CLE Cleveland Hopkins Intl - STI Santiago de los Caballeros

CLESTI

Cleveland Hopkins Intl

Sun 10/11

6:00 am-5:33 pm

1 stop11h 33m

Santiago de los Caballeros

Tue 10/20

7:05 pm-10:51 am

1 stop15h 46m

$480

ClevelandSantiago de los Caballeros

CLE Cleveland Hopkins Intl - STI Santiago de los Caballeros

CLESTI

Cleveland Hopkins Intl

Sun 10/11

6:00 am-5:33 pm

1 stop11h 33m

Santiago de los Caballeros

Fri 10/23

7:05 pm-10:51 am

1 stop15h 46m

$480

ClevelandSantiago de los Caballeros

CLE Cleveland Hopkins Intl - STI Santiago de los Caballeros

CLESTI

Cleveland Hopkins Intl

Wed 10/14

6:00 am-5:33 pm

1 stop11h 33m

Santiago de los Caballeros

Thu 10/22

7:05 pm-10:51 am

1 stop15h 46m

$480

ClevelandSantiago de los Caballeros

CLE Cleveland Hopkins Intl - STI Santiago de los Caballeros

CLESTI

Cleveland Hopkins Intl

Fri 10/16

8:00 am-2:45 pm

1 stop6h 45m

Santiago de los Caballeros

Sat 10/17

3:55 pm-11:59 pm

1 stop8h 04m

$556
Quickest round-trip

ClevelandSantiago de los Caballeros

CLE Cleveland Hopkins Intl - STI Santiago de los Caballeros

CLESTI

Cleveland Hopkins Intl

Tue 10/6

7:00 am-1:27 pm

1 stop6h 27m

Santiago de los Caballeros

Fri 10/9

3:15 pm-10:54 pm

1 stop7h 39m

$556

ClevelandSantiago de los Caballeros

CLE Cleveland Hopkins Intl - STI Santiago de los Caballeros

CLESTI

Cleveland Hopkins Intl

Fri 10/16

8:00 am-2:45 pm

1 stop6h 45m

Santiago de los Caballeros

Thu 10/22

3:55 pm-11:59 pm

1 stop8h 04m

$556

ClevelandSantiago de los Caballeros

CLE Cleveland Hopkins Intl - STI Santiago de los Caballeros

CLESTI

Cleveland Hopkins Intl

Sun 9/20

6:19 am-2:15 pm

1 stop7h 56m

Santiago de los Caballeros

Sat 9/26

3:15 pm-11:46 pm

1 stop8h 31m

$567

ClevelandSantiago de los Caballeros

CLE Cleveland Hopkins Intl - STI Santiago de los Caballeros

CLESTI

Cleveland Hopkins Intl

Sun 9/20

7:40 pm-2:15 pm

2 stops18h 35m

Santiago de los Caballeros

Sat 9/26

3:15 pm-9:15 am

2 stops18h 00m

$572

ClevelandSantiago de los Caballeros

CLE Cleveland Hopkins Intl - STI Santiago de los Caballeros

CLESTI

Cleveland Hopkins Intl

Sun 9/20

8:05 am-12:57 pm

1 stop28h 52m

Santiago de los Caballeros

Sat 9/26

6:00 am-9:59 pm

1 stop15h 59m

$641

ClevelandSantiago de los Caballeros

CLE Cleveland Hopkins Intl - STI Santiago de los Caballeros

CLESTI

Cleveland Hopkins Intl

Sun 9/6

8:05 am-10:52 pm

1 stop14h 47m

Santiago de los Caballeros

Wed 9/16

6:00 am-9:51 pm

1 stop15h 51m

$647

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Cleveland to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Cleveland is in January. Flight prices, which tend to average around $461, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of January, then flying in November is also cheap. Prices for this month can be found on momondo for an average of $485.

How have Cleveland to Santiago de los Caballeros flight prices changed over time?

As of August 2026, prices for Cleveland to Santiago de los Caballeros flights are approximately 130% more expensive when compared to flights at the same time last year.

When to book flights from Cleveland to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Cleveland to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Cleveland to Santiago de los Caballeros (CLE to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Cleveland to Santiago de los Caballeros

Best Price Found

$225

Fastest flight time

6h 27m

Direct flights

None
The best one-way flight to Santiago de los Caballeros from Cleveland in the past 72 hours is $225. The best round-trip flight deal from Cleveland to Santiago de los Caballeros found on momondo in the last 72 hours is $480.
The fastest flight from Cleveland to Santiago de los Caballeros takes 6h 27m
There are no direct flights from Cleveland to Santiago de los Caballeros. There are no popular flight routes from Cleveland to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from Cleveland to Santiago de los Caballeros

  • How far is Cleveland Hopkins Intl to Santiago de los Caballeros by plane?

    Cleveland Hopkins Intl and Santiago de los Caballeros are 1653.6 mi apart from one another. By plane, this route typically takes 6h 27m.

  • When did momondo last update prices for flights from Cleveland Hopkins Intl Airport to Santiago de los Caballeros Airport?

    Prices for flights from Cleveland Hopkins Intl Airport to Santiago de los Caballeros Airport are updated daily.

  • How many operators does momondo search for flights from Cleveland Hopkins Intl Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Cleveland Hopkins Intl Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Cleveland Hopkins Intl Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents you'll need for your trip to Santiago de los Caballeros Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Santiago de los Caballeros Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Cleveland to Santiago de los Caballeros?

Best airlines flying from Cleveland to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Cleveland to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $231Free CancellationRating
7.8
8,503 reviews
Search Delta flights
JetBluePriceFrom $431Free CancellationRating
7.1
3,033 reviews
Search JetBlue flights
American AirlinesPriceFrom $440Free CancellationRating
7.1
11,954 reviews
Search American Airlines flights
United AirlinesPriceFrom $456Free CancellationRating
7.4
10,103 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Cleveland to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Cleveland.

Can I find flights from Cleveland to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago de los Caballeros from Cleveland with this policy.

How can momondo help me find flights from Cleveland to Santiago de los Caballeros?

Once all potential Cleveland to Santiago de los Caballeros flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Cleveland to Santiago de los Caballeros right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Santiago de los Caballeros from Cleveland. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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