Which layover airport offers the lowest fares from Chicago to Panama City?

Flights via Atlanta (ATL) offer the lowest average round-trip price of $479.

Which airline has the best punctuality record on Chicago to Panama City flights?

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 8% of their flights experiencing any sort of delay.

Which layover airport has the shortest travel time from Chicago to Panama City?

Flights connecting via Miami (MIA) have the shortest average one-way travel time: 6h 59m.

What day of the week experiences the fewest flight delays on this route?

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

What airlines fly to Panama City?

Copa Airlines, United Airlines and Avianca are the top three most popular airlines that fly to Panama City from Chicago according to our data. Copa Airlines is the first choice among our users, with 79% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 5 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

How many flights depart from Chicago to Panama City on average per day?

The number of flights available between Chicago and Panama City is 3 per day as of December 2025. The most frequent departure time is 7:00AM, with 70% of daily flights leaving at noon.

Which layover airport has the shortest connection time from Chicago to Panama City?

Miami (MIA) has the shortest average layover time for this route: 1h 14m.

How many flights depart from Chicago to Panama City on average per week?

As of December 2025, there are 24 flights per week flying from Chicago to Panama City. The most common day of the week flights depart is Mon, with 21% of flights taking off on this day.

How often are flights from Chicago to Panama City delayed?

Historically, on average around 8% of flights between Chicago and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 120 minutes.

Which airport is the most popular layover for flights between Chicago and Panama City?

Bogotá (BOG) was the most common stop: 52% of momondo users choosing 1-stop flights on this route connected there.

What is the cheapest airline that flies from Chicago to Panama City Tocumen Intl?

Avianca is the most popular carrier operating from Chicago to Panama City Tocumen Intl

What is the most punctual flight time for Chicago to Panama City flights?

Generally, flights departing in the evening tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

When did momondo last update prices for flights from Chicago to Panama City Tocumen Intl Airport?

Prices for flights from Chicago to Panama City Tocumen Intl Airport refresh daily.

How many operators does momondo search for flights from Chicago to Panama City Tocumen Intl Airport?

As of December 2025, there are 5 operators available to choose from for flights from Chicago to Panama City Tocumen Intl Airport.

How old do you have to be to fly from Chicago to Panama City Tocumen Intl Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Panama City Tocumen Intl Airport.

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$190 Cheap Flights from Chicago to Panama City in 2025/26

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9:23 am - 10:30 am

ORD

PTY

24h 07m3 stops

2:55 am - 6:16 pm

PTY

ORD

16h 21m2 stops

$477Multiple Airlines

Thu, Jan 22 - Wed, Jan 28

6:57 pm - 8:50 am

ORD

PTY

12h 53m2 stops

6:15 pm - 8:18 am

PTY

ORD

15h 03m1 stop

$484Multiple Airlines

Mon, Jan 19 - Mon, Jan 26

6:57 pm - 8:06 am

ORD

PTY

12h 09m1 stop

9:33 pm - 9:39 am

PTY

ORD

13h 06m1 stop

$495Multiple Airlines

Mon, Feb 9 - Tue, Feb 17

6:57 pm - 8:50 am

ORD

PTY

12h 53m2 stops

6:34 pm - 8:18 am

PTY

ORD

14h 44m1 stop

$498Multiple Airlines

Fri, Jan 23 - Fri, Jan 30

7:20 am - 8:50 am

ORD

PTY

24h 30m2 stops

2:55 am - 9:03 pm

PTY

ORD

19h 08m2 stops

$500Multiple Airlines

Thu, Jan 22 - Wed, Jan 28

9:23 am - 8:37 pm

ORD

PTY

10h 14m1 stop

9:33 pm - 8:18 am

PTY

ORD

11h 45m1 stop

$502Multiple Airlines

Wed, Jan 28 - Mon, Feb 9

6:57 pm - 8:40 am

ORD

PTY

12h 43m1 stop

9:33 pm - 8:18 am

PTY

ORD

11h 45m1 stop

$503Multiple Airlines

Sun, Feb 1 - Mon, Feb 9

9:23 am - 10:30 am

ORD

PTY

24h 07m3 stops

5:50 pm - 10:38 pm

PTY

ORD

29h 48m3 stops

$504Multiple Airlines

Thu, Feb 5 - Mon, Feb 9

6:00 am - 1:55 pm

MDW

PTY

6h 55m1 stop

3:20 pm - 10:42 pm

PTY

MDW

8h 22m1 stop

$604Delta

Wed, Feb 25 - Sun, Mar 1

6:00 am - 12:55 pm

MDW

PTY

6h 55m1 stop

2:20 pm - 8:42 am

PTY

MDW

18h 22m2 stops

$608Delta

Mon, Apr 20 - Sat, Apr 25

United Airlines flights from Chicago to Panama City

Our best United Airlines deals on Chicago to Panama City flight tickets

United Airlines

Dec 21

ORD9:23 pmChicago O'Hare Intl

18h 44m

1 stop

PTY5:07 pmPanama City Tocumen Intl

Dec 31

PTY11:55 pmPanama City Tocumen Intl

10h 15m

1 stop

ORD9:10 amChicago O'Hare Intl

$748

Find similar

United Airlines

Dec 17

ORD7:35 amChicago O'Hare Intl

11h 03m

1 stop

PTY7:38 pmPanama City Tocumen Intl

Dec 24

PTY4:41 pmPanama City Tocumen Intl

8h 33m

1 stop

ORD12:14 amChicago O'Hare Intl

$757

Find similar

United Airlines

Dec 21

ORD8:05 pmChicago O'Hare Intl

20h 02m

1 stop

PTY5:07 pmPanama City Tocumen Intl

Dec 28

PTY8:55 amPanama City Tocumen Intl

10h 50m

1 stop

ORD6:45 pmChicago O'Hare Intl

$770

Find similar

Avianca flights from Chicago to Panama City

Our best Avianca deals on Chicago to Panama City flight tickets

Avianca

Feb 5

ORD10:20 pmChicago O'Hare Intl

17h 35m

1 stop

PTY4:55 pmPanama City Tocumen Intl

Feb 7

PTY2:55 amPanama City Tocumen Intl

18h 25m

1 stop

ORD8:20 pmChicago O'Hare Intl

$541

Find similar

Avianca

Jan 6

ORD4:10 pmChicago O'Hare Intl

17h 20m

1 stop

PTY10:30 amPanama City Tocumen Intl

Jan 20

PTY2:55 amPanama City Tocumen Intl

18h 25m

1 stop

ORD8:20 pmChicago O'Hare Intl

$552

Find similar

Avianca

Jan 3

ORD4:10 pmChicago O'Hare Intl

17h 20m

1 stop

PTY10:30 amPanama City Tocumen Intl

Jan 31

PTY2:55 amPanama City Tocumen Intl

18h 25m

1 stop

ORD8:20 pmChicago O'Hare Intl

$575

Find similar

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/22

9:23 am-10:30 am

3 stops24h 07m

Panama City Tocumen Intl

Wed 1/28

2:55 am-6:16 pm

2 stops16h 21m

$477

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 1/19

6:57 pm-8:50 am

2 stops12h 53m

Panama City Tocumen Intl

Mon 1/26

6:15 pm-8:18 am

1 stop15h 03m

$484

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 2/9

6:57 pm-8:06 am

1 stop12h 09m

Panama City Tocumen Intl

Tue 2/17

9:33 pm-9:39 am

1 stop13h 06m

$495

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 1/23

6:57 pm-8:50 am

2 stops12h 53m

Panama City Tocumen Intl

Fri 1/30

6:34 pm-8:18 am

1 stop14h 44m

$498

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/22

7:20 am-8:50 am

2 stops24h 30m

Panama City Tocumen Intl

Wed 1/28

2:55 am-9:03 pm

2 stops19h 08m

$500

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 1/28

9:23 am-8:37 pm

1 stop10h 14m

Panama City Tocumen Intl

Mon 2/9

9:33 pm-8:18 am

1 stop11h 45m

$502

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 2/1

6:57 pm-8:40 am

1 stop12h 43m

Panama City Tocumen Intl

Mon 2/9

9:33 pm-8:18 am

1 stop11h 45m

$503

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 2/5

9:23 am-10:30 am

3 stops24h 07m

Panama City Tocumen Intl

Mon 2/9

5:50 pm-10:38 pm

3 stops29h 48m

$504

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Wed 2/25

6:00 am-1:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Sun 3/1

3:20 pm-10:42 pm

1 stop8h 22m

$604

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Mon 4/20

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Sat 4/25

2:20 pm-8:42 am

2 stops18h 22m

$608

Flights are sorted by cheapest round-trip flights first.

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How to get the cheapest flight ticket from Chicago to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Delays

Layovers

Other information

What is the cheapest month to fly to Panama City?

In general, July is the cheapest month to fly from Chicago to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $523. If you’re not able to fly to Panama City in July, then September is your next best option. Flight prices from Chicago to Panama City during September average around $548.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $528. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $587. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Chicago to Panama City during this time can be as low as $499. Try not to purchase tickets in the morning because they tend to be around $578. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago to Panama City Tocumen Intl flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $584 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Chicago for as low as $538 on momondo.

What cabin class options are available on Chicago to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Chicago to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Panama City flights?

You could potentially save up to 34% on your flight if you consider stops on a Chicago to Panama City flight.

How have Chicago to Panama City flight prices changed over time?

When to book flights from Chicago to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Panama City according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Chicago to Panama City (CHI to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Panama City

Best Price Found	$207
Fastest flight time	5h 13m
Direct flights	Every day
Airports in Panama City	1 airport

The best one-way flight to Panama City from Chicago in the past 72 hours is $207. The best round-trip flight deal from Chicago to Panama City found on momondo in the last 72 hours is $430.

The fastest flight from Chicago to Panama City takes 5h 13m

Direct flights go from Chicago to Panama City every day.

There is 1 airport in Panama City. From Chicago there are direct flights to Panama City Tocumen Intl (PTY).

Search flight deals

How far is Chicago to Panama City Tocumen Intl by plane?
The straight-line distance from Chicago to Panama City Tocumen Intl is 2323.9 mi. Typically, this will take 5h 13m by plane in normal conditions.
When did momondo last update prices for flights from Chicago to Panama City Tocumen Intl Airport?
Prices for flights from Chicago to Panama City Tocumen Intl Airport refresh daily.
How many operators does momondo search for flights from Chicago to Panama City Tocumen Intl Airport?
As of December 2025, there are 5 operators available to choose from for flights from Chicago to Panama City Tocumen Intl Airport.
How old do you have to be to fly from Chicago to Panama City Tocumen Intl Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Panama City Tocumen Intl Airport.
What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?
The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Chicago to Panama City?
momondo data reveals that the most frequently booked plane model on the route from Chicago to Panama City is Boeing 737-800, representing 40.78% of all bookings. The subsequent popular models are Airbus A320neo at 28.16%, Boeing 737 MAX 8 at 11.04%, and Boeing 737 MAX 9 at 9.59%.
What is the most popular airline from Chicago to Panama City?
momondo data reveals that the most frequently booked airline on the route from Chicago to Panama City is Copa Airlines, representing 75% of all bookings. The subsequent popular airlines are Avianca at 11%, United Airlines at 8%, and Delta at 5%.

Best airlines flying from Chicago to Panama City

Compare and see reviews for airlines that fly from Chicago to Panama City with momondo

Airline	Rating	Free Cancellation	Price
Avianca	PriceFrom $358	Free Cancellation	Rating 6.6 2,478 reviews	Search Avianca flights
Copa Airlines	PriceFrom $464	Free Cancellation	Rating 7.6 1,558 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $479	Free Cancellation	Rating 7.4 9,095 reviews	Search United Airlines flights
Delta	PriceFrom $479	Free Cancellation	Rating 7.9 8,008 reviews	Search Delta flights
American Airlines	PriceFrom $589	Free Cancellation	Rating 7.2 11,048 reviews	Search American Airlines flights

Copa Airlines Flights From Chicago to Panama City
Copa Airlines flies from Chicago to Panama City around 10 times per week, with 1,558 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Chicago to Panama City in the last 72 hours was $464 (round-trip), much lower than the average airfare cost of $579 for Copa Airlines flights on this route.
United Airlines Flights From Chicago to Panama City
United Airlines (7.4/10 from 9,095 reviews) operates around 10 flights from Chicago to Panama City in any given week. The average United Airlines airfare for this route is around $653, with deals from around $479 rare but found on momondo. Referenced prices are for round-trip Chicago to Panama City flight searches in the last 72 hours.

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Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Chicago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Chicago to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Chicago to Panama City.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Find better results for your trip to Panama

Airports servicing Panama

Puerto Piña Bahia Pinas Airport

Bocas Del Toro Airport

Changuinola Airport

David Enrique Malek Airport

Jaque Airport

Mulatupo Airport

Puerto Obaldia Airport

Playon Chico Airport

Cheap flights from Chicago to Panama City from $190

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Panama City departing on 1/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Chicago to Panama City

What is the cheapest month to fly to Panama City?

What is the cheapest day to depart on your flight to Panama City?

What is the cheapest time of day to depart on your flight to Panama City?

What is the cheapest Chicago to Panama City Tocumen Intl flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

What cabin class options are available on Chicago to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Chicago to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Panama City flights?

You could potentially save up to 34% on your flight if you consider stops on a Chicago to Panama City flight.

How have Chicago to Panama City flight prices changed over time?

What is the cheapest airline that flies from Chicago to Panama City Tocumen Intl?

Avianca is the most popular carrier operating from Chicago to Panama City Tocumen Intl

What airlines fly to Panama City?

How often are flights from Chicago to Panama City delayed?

Historically, on average around 8% of flights between Chicago and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 120 minutes.

What is the most punctual flight time for Chicago to Panama City flights?

Generally, flights departing in the evening tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

What day of the week experiences the fewest flight delays on this route?

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

Which airline has the best punctuality record on Chicago to Panama City flights?

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 8% of their flights experiencing any sort of delay.

Which airport is the most popular layover for flights between Chicago and Panama City?

Bogotá (BOG) was the most common stop: 52% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Chicago to Panama City?

Flights via Atlanta (ATL) offer the lowest average round-trip price of $479.

Which layover airport has the shortest travel time from Chicago to Panama City?

Flights connecting via Miami (MIA) have the shortest average one-way travel time: 6h 59m.

Which layover airport has the shortest connection time from Chicago to Panama City?

Miami (MIA) has the shortest average layover time for this route: 1h 14m.

How many flights depart from Chicago to Panama City on average per day?

The number of flights available between Chicago and Panama City is 3 per day as of December 2025. The most frequent departure time is 7:00AM, with 70% of daily flights leaving at noon.

How many flights depart from Chicago to Panama City on average per week?

As of December 2025, there are 24 flights per week flying from Chicago to Panama City. The most common day of the week flights depart is Mon, with 21% of flights taking off on this day.

When to book flights from Chicago to Panama City

Cheap Chicago to Panama City (CHI to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Panama City

Best Price Found

Fastest flight time

Direct flights

Airports in Panama City

How far is Chicago to Panama City Tocumen Intl by plane?

When did momondo last update prices for flights from Chicago to Panama City Tocumen Intl Airport?

How many operators does momondo search for flights from Chicago to Panama City Tocumen Intl Airport?

How old do you have to be to fly from Chicago to Panama City Tocumen Intl Airport?

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

What is the most popular plane model from Chicago to Panama City?

What is the most popular airline from Chicago to Panama City?

Best airlines flying from Chicago to Panama City

Compare and see reviews for airlines that fly from Chicago to Panama City with momondo

Copa Airlines Flights From Chicago to Panama City

United Airlines Flights From Chicago to Panama City

Traveling to a place near Panama City?

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

How can momondo help me find flights from Chicago to Panama City?