What airlines fly to Panama City?

Copa Airlines, United Airlines and Avianca are the top three most popular airlines that fly to Panama City from Chicago according to our data. Copa Airlines is the first choice among our users, with 82% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 5 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

What is the most punctual flight time for Chicago to Panama City flights?

Generally, flights departing in the evening tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

What day of the week experiences the fewest flight delays on this route?

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

How many flights depart from Chicago to Panama City on average per day?

The number of flights available between Chicago and Panama City is 4 per day as of January 2026. The most frequent departure time is 7:00AM, with 69% of daily flights leaving at noon.

Which layover airport has the shortest travel time from Chicago to Panama City?

Flights connecting via Miami (MIA) have the shortest average one-way travel time: 6h 59m.

Which airline has the best punctuality record on Chicago to Panama City flights?

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 9% of their flights experiencing any sort of delay.

What is the cheapest airline that flies from Chicago to Panama City Tocumen Intl?

Avianca is the most popular carrier operating from Chicago to Panama City Tocumen Intl

Which airport is the most popular layover for flights between Chicago and Panama City?

Bogotá (BOG) was the most common stop: 57% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Chicago to Panama City?

Flights via Atlanta (ATL) offer the lowest average round-trip price of $479.

How many flights depart from Chicago to Panama City on average per week?

As of January 2026, there are 33 flights per week flying from Chicago to Panama City. The most common day of the week flights depart is Tue, with 18% of flights taking off on this day.

Which layover airport has the shortest connection time from Chicago to Panama City?

Houston (IAH) has the shortest average layover time for this route: 1h 05m.

How often are flights from Chicago to Panama City delayed?

Historically, on average around 10% of flights between Chicago and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 128 minutes.

When did momondo last update prices for flights from Chicago to Panama City Tocumen Intl Airport?

Prices for flights from Chicago to Panama City Tocumen Intl Airport refresh daily.

How many operators does momondo search for flights from Chicago to Panama City Tocumen Intl Airport?

As of January 2026, there are 5 operators available to choose from for flights from Chicago to Panama City Tocumen Intl Airport.

How old do you have to be to fly from Chicago to Panama City Tocumen Intl Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Panama City Tocumen Intl Airport.

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$100 Cheap Flights from Chicago to Panama City in 2026

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Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

11:20 pm - 8:50 am

ORD

PTY

9h 30m

1 stop

10:05 pm - 1:15 pm

PTY

ORD

15h 10m

1 stop

$447Avianca

Thu, Mar 19 - Sun, Apr 5

2:35 pm - 12:10 am

ORD

PTY

9h 35m

1 stop

5:30 am - 6:35 pm

PTY

ORD

13h 05m

2 stops

$448Multiple Airlines

Sun, Mar 29 - Wed, Apr 8

11:20 pm - 8:50 am

ORD

PTY

9h 30m

1 stop

5:50 pm - 8:25 am

PTY

ORD

14h 35m

2 stops

$450Multiple Airlines

Mon, Mar 23 - Thu, Mar 26

11:20 pm - 8:50 am

ORD

PTY

9h 30m

1 stop

3:20 am - 1:15 pm

PTY

ORD

9h 55m

1 stop

$453Avianca

Fri, Mar 20 - Tue, Mar 31

6:51 pm - 10:30 am

ORD

PTY

14h 39m

2 stops

9:45 am - 9:20 pm

PTY

ORD

11h 35m

1 stop

$456Multiple Airlines

Sun, Mar 1 - Sat, Mar 21

10:20 pm - 2:00 pm

ORD

PTY

14h 40m

1 stop

9:45 am - 8:20 pm

PTY

ORD

11h 35m

1 stop

$457Avianca

Mon, Feb 16 - Sat, Feb 21

6:51 pm - 10:30 am

ORD

PTY

14h 39m

2 stops

9:45 am - 9:20 pm

PTY

ORD

11h 35m

1 stop

$460Multiple Airlines

Sat, Mar 7 - Sat, Mar 14

2:35 pm - 12:45 am

ORD

PTY

10h 10m

1 stop

3:20 am - 6:15 pm

PTY

ORD

14h 55m

2 stops

$461Multiple Airlines

Wed, Apr 29 - Sat, May 9

6:00 am - 1:03 pm

MDW

PTY

7h 03m

1 stop

2:20 pm - 10:29 pm

PTY

MDW

8h 09m

1 stop

$625Delta

Tue, Apr 7 - Mon, Apr 20

6:00 am - 1:03 pm

MDW

PTY

7h 03m

1 stop

2:20 pm - 8:47 am

PTY

MDW

18h 27m

2 stops

$629Delta

Sun, Apr 12 - Wed, Apr 29

Delta flights from Chicago to Panama City

Our best Delta deals on Chicago to Panama City flight tickets

Delta

Mar 17

MDW6:00 amChicago Midway

7h 03m

1 stop

PTY1:03 pmPanama City Tocumen Intl

Mar 24

PTY2:28 pmPanama City Tocumen Intl

8h 03m

1 stop

MDW10:31 pmChicago Midway

$645

Delta

Mar 17

MDW6:34 pmChicago Midway

18h 29m

2 stops

PTY1:03 pmPanama City Tocumen Intl

Mar 24

PTY2:28 pmPanama City Tocumen Intl

8h 03m

1 stop

MDW10:31 pmChicago Midway

$649

Delta

Mar 12

MDW6:00 amChicago Midway

7h 03m

1 stop

PTY1:03 pmPanama City Tocumen Intl

Mar 18

PTY2:28 pmPanama City Tocumen Intl

19h 28m

1 stop

MDW9:56 amChicago Midway

$671

Avianca flights from Chicago to Panama City

Our best Avianca deals on Chicago to Panama City flight tickets

Avianca

Mar 19

ORD11:20 pmChicago O'Hare Intl

9h 30m

1 stop

PTY8:50 amPanama City Tocumen Intl

Apr 3

PTY3:25 amPanama City Tocumen Intl

9h 50m

1 stop

ORD1:15 pmChicago O'Hare Intl

$447

Avianca

Mar 20

ORD11:20 pmChicago O'Hare Intl

9h 30m

1 stop

PTY8:50 amPanama City Tocumen Intl

Mar 31

PTY3:20 amPanama City Tocumen Intl

9h 55m

1 stop

ORD1:15 pmChicago O'Hare Intl

$453

Avianca

Feb 16

ORD10:20 pmChicago O'Hare Intl

14h 40m

1 stop

PTY2:00 pmPanama City Tocumen Intl

Feb 21

PTY9:45 amPanama City Tocumen Intl

11h 35m

1 stop

ORD8:20 pmChicago O'Hare Intl

$457

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 3/19

11:20 pm-8:50 am

1 stop9h 30m

Panama City Tocumen Intl

Sun 4/5

10:05 pm-1:15 pm

1 stop15h 10m

$447

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 3/29

2:35 pm-12:10 am

1 stop9h 35m

Panama City Tocumen Intl

Wed 4/8

5:30 am-6:35 pm

2 stops13h 05m

$448

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 3/23

11:20 pm-8:50 am

1 stop9h 30m

Panama City Tocumen Intl

Thu 3/26

5:50 pm-8:25 am

2 stops14h 35m

$450

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 3/20

11:20 pm-8:50 am

1 stop9h 30m

Panama City Tocumen Intl

Tue 3/31

3:20 am-1:15 pm

1 stop9h 55m

$453

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 3/1

6:51 pm-10:30 am

2 stops14h 39m

Panama City Tocumen Intl

Sat 3/21

9:45 am-9:20 pm

1 stop11h 35m

$456

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 2/16

10:20 pm-2:00 pm

1 stop14h 40m

Panama City Tocumen Intl

Sat 2/21

9:45 am-8:20 pm

1 stop11h 35m

$457

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 3/7

6:51 pm-10:30 am

2 stops14h 39m

Panama City Tocumen Intl

Sat 3/14

9:45 am-9:20 pm

1 stop11h 35m

$460

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 4/29

2:35 pm-12:45 am

1 stop10h 10m

Panama City Tocumen Intl

Sat 5/9

3:20 am-6:15 pm

2 stops14h 55m

$461

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 4/7

6:00 am-1:03 pm

1 stop7h 03m

Panama City Tocumen Intl

Mon 4/20

2:20 pm-10:29 pm

1 stop8h 09m

$625

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 4/12

6:00 am-1:03 pm

1 stop7h 03m

Panama City Tocumen Intl

Wed 4/29

2:20 pm-8:47 am

2 stops18h 27m

$629

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How to get the cheapest flight ticket from Chicago to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Delays

Layovers

Other information

What is the cheapest month to fly to Panama City?

In general, July is the cheapest month to fly from Chicago to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $523. If you’re not able to fly to Panama City in July, then September is your next best option. Flight prices from Chicago to Panama City during September average around $534.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $530. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $584. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Chicago to Panama City during this time can be as low as $496. Try not to purchase tickets in the morning because they tend to be around $577. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago to Panama City Tocumen Intl flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $585 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Chicago for as low as $535 on momondo.

What cabin class options are available on Chicago to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Chicago to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Panama City flights?

You could potentially save up to 81% on your flight if you consider stops on a Chicago to Panama City flight.

How have Chicago to Panama City flight prices changed over time?

When to book flights from Chicago to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Panama City according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Chicago to Panama City (CHI to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Panama City

Best Price Found	$179
Fastest flight time	5h 13m
Direct flights	Every day
Airports in Panama City	1 airport

The best one-way flight to Panama City from Chicago in the past 72 hours is $179. The best round-trip flight deal from Chicago to Panama City found on momondo in the last 72 hours is $376.

The fastest flight from Chicago to Panama City takes 5h 13m

Direct flights go from Chicago to Panama City every day.

There is 1 airport in Panama City. From Chicago there are direct flights to Panama City Tocumen Intl (PTY).

Search flight deals

How far is Chicago to Panama City Tocumen Intl by plane?
The straight-line distance from Chicago to Panama City Tocumen Intl is 2323.9 mi. Typically, this will take 5h 13m by plane in normal conditions.
When did momondo last update prices for flights from Chicago to Panama City Tocumen Intl Airport?
Prices for flights from Chicago to Panama City Tocumen Intl Airport refresh daily.
How many operators does momondo search for flights from Chicago to Panama City Tocumen Intl Airport?
As of January 2026, there are 5 operators available to choose from for flights from Chicago to Panama City Tocumen Intl Airport.
How old do you have to be to fly from Chicago to Panama City Tocumen Intl Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Panama City Tocumen Intl Airport.
What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?
The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Chicago to Panama City?
momondo data reveals that the most frequently booked plane model on the route from Chicago to Panama City is Boeing 737-800, representing 39.95% of all bookings. The subsequent popular models are Airbus A320neo at 25.09%, Boeing 737 MAX 8 at 13.91%, and Boeing 737 MAX 9 at 10.11%.
What is the most popular airline from Chicago to Panama City?
momondo data reveals that the most frequently booked airline on the route from Chicago to Panama City is Copa Airlines, representing 79% of all bookings. The subsequent popular airlines are Avianca at 9%, United Airlines at 6%, and Delta at 4%.

Best airlines flying from Chicago to Panama City

Compare and see reviews for airlines that fly from Chicago to Panama City with momondo

Airline	Rating	Free Cancellation	Price
Avianca	PriceFrom $272	Free Cancellation	Rating 6.6 2,496 reviews	Search Avianca flights
Copa Airlines	PriceFrom $463	Free Cancellation	Rating 7.6 1,557 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $479	Free Cancellation	Rating 7.4 9,190 reviews	Search United Airlines flights
Delta	PriceFrom $479	Free Cancellation	Rating 7.9 8,087 reviews	Search Delta flights
American Airlines	PriceFrom $563	Free Cancellation	Rating 7.2 11,173 reviews	Search American Airlines flights

Copa Airlines Flights From Chicago to Panama City
Copa Airlines flies from Chicago to Panama City around 14 times per week, with 1,557 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Chicago to Panama City in the last 72 hours was $463 (round-trip), much lower than the average airfare cost of $580 for Copa Airlines flights on this route.
United Airlines Flights From Chicago to Panama City
United Airlines (7.4/10 from 9,190 reviews) operates around 12 flights from Chicago to Panama City in any given week. The average United Airlines airfare for this route is around $653, with deals from around $479 rare but found on momondo. Referenced prices are for round-trip Chicago to Panama City flight searches in the last 72 hours.

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Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Chicago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Chicago to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Chicago to Panama City.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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Airports servicing Panama

Puerto Piña Bahia Pinas Airport

Bocas Del Toro Airport

Changuinola Airport

David Enrique Malek Airport

Jaque Airport

Mulatupo Airport

Puerto Obaldia Airport

Playon Chico Airport

Cheap flights from Chicago to Panama City from $100

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Panama City departing on 4/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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How to get the cheapest flight ticket from Chicago to Panama City

What is the cheapest month to fly to Panama City?

What is the cheapest day to depart on your flight to Panama City?

What is the cheapest time of day to depart on your flight to Panama City?

What is the cheapest Chicago to Panama City Tocumen Intl flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

What cabin class options are available on Chicago to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Chicago to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Panama City flights?

You could potentially save up to 81% on your flight if you consider stops on a Chicago to Panama City flight.

How have Chicago to Panama City flight prices changed over time?

What is the cheapest airline that flies from Chicago to Panama City Tocumen Intl?

Avianca is the most popular carrier operating from Chicago to Panama City Tocumen Intl

What airlines fly to Panama City?

How often are flights from Chicago to Panama City delayed?

Historically, on average around 10% of flights between Chicago and Panama City have experienced a delay on any given week. The average delay length over the past 12 months has been 128 minutes.

What is the most punctual flight time for Chicago to Panama City flights?

Generally, flights departing in the evening tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

What day of the week experiences the fewest flight delays on this route?

Saturday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

Which airline has the best punctuality record on Chicago to Panama City flights?

According to our data, Copa Airlines have had the least number of delays on this route over the last 12 months; with about 9% of their flights experiencing any sort of delay.

Which airport is the most popular layover for flights between Chicago and Panama City?

Bogotá (BOG) was the most common stop: 57% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Chicago to Panama City?

Flights via Atlanta (ATL) offer the lowest average round-trip price of $479.

Which layover airport has the shortest travel time from Chicago to Panama City?

Flights connecting via Miami (MIA) have the shortest average one-way travel time: 6h 59m.

Which layover airport has the shortest connection time from Chicago to Panama City?

Houston (IAH) has the shortest average layover time for this route: 1h 05m.

How many flights depart from Chicago to Panama City on average per day?

The number of flights available between Chicago and Panama City is 4 per day as of January 2026. The most frequent departure time is 7:00AM, with 69% of daily flights leaving at noon.

How many flights depart from Chicago to Panama City on average per week?

As of January 2026, there are 33 flights per week flying from Chicago to Panama City. The most common day of the week flights depart is Tue, with 18% of flights taking off on this day.

When to book flights from Chicago to Panama City

Cheap Chicago to Panama City (CHI to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Panama City

Best Price Found

Fastest flight time

Direct flights

Airports in Panama City

How far is Chicago to Panama City Tocumen Intl by plane?

When did momondo last update prices for flights from Chicago to Panama City Tocumen Intl Airport?

How many operators does momondo search for flights from Chicago to Panama City Tocumen Intl Airport?

How old do you have to be to fly from Chicago to Panama City Tocumen Intl Airport?

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

What is the most popular plane model from Chicago to Panama City?

What is the most popular airline from Chicago to Panama City?

Best airlines flying from Chicago to Panama City

Compare and see reviews for airlines that fly from Chicago to Panama City with momondo

Copa Airlines Flights From Chicago to Panama City

United Airlines Flights From Chicago to Panama City

Traveling to a place near Panama City?

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

How can momondo help me find flights from Chicago to Panama City?