Which layover airport has the shortest travel time from Chicago to Panama City?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 7h 02m.

How many flights depart from Chicago to Panama City on average per day?

The number of flights available between Chicago and Panama City is 3 per day as of November 2025. The most frequent departure time is 2:00PM, with 57% of daily flights leaving in the afternoon.

Which layover airport offers the lowest fares from Chicago to Panama City?

Flights via Bogotá (BOG) offer the lowest average round-trip price of $440.

Which layover airport has the shortest connection time from Chicago to Panama City?

Houston (IAH) has the shortest average layover time for this route: 1h 15m.

What is the cheapest airline that flies from Chicago to Panama City Tocumen Intl?

Avianca and Aeromexico are the most popular carriers operating from Chicago to Panama City Tocumen Intl

What airlines fly to Panama City?

Copa Airlines, United Airlines and Avianca are the top three most popular airlines that fly to Panama City from Chicago according to our data. Copa Airlines is the first choice among our users, with 78% of people opting to fly with this airline when traveling to Panama City. Keep in mind that there are 5 different airlines that fly to Panama City on a routine basis, so you have a few additional options to choose from.

Which airport is the most popular layover for flights between Chicago and Panama City?

Bogotá (BOG) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

How many flights depart from Chicago to Panama City on average per week?

As of November 2025, there are 22 flights per week flying from Chicago to Panama City. The most common day of the week flights depart is Mon, with 23% of flights taking off on this day.

When did momondo last update prices for flights from Chicago to Panama City Tocumen Intl Airport?

Prices for flights from Chicago to Panama City Tocumen Intl Airport refresh daily.

How many operators does momondo search for flights from Chicago to Panama City Tocumen Intl Airport?

As of November 2025, there are 5 operators available to choose from for flights from Chicago to Panama City Tocumen Intl Airport.

How old do you have to be to fly from Chicago to Panama City Tocumen Intl Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Panama City Tocumen Intl Airport.

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$207 Cheap Flights from Chicago to Panama City in 2025/26

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Cheap round-trip flights

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10:20 pm - 4:55 pmORD-PTY

17h 35m1 stop

2:55 am - 8:20 pmPTY-ORD

18h 25m1 stop

$451Avianca

Find Deal

Thu, Feb 5 - Sat, Feb 7

6:57 pm - 8:06 amORD-PTY

12h 09m1 stop

9:33 pm - 7:54 amPTY-ORD

11h 21m1 stop

$462Multiple Airlines

Find Deal

Thu, Jan 29 - Sun, Feb 8

6:57 pm - 8:06 amORD-PTY

12h 09m1 stop

9:33 pm - 7:54 amPTY-ORD

11h 21m1 stop

$465Multiple Airlines

Find Deal

Sun, Jan 18 - Sun, Jan 25

6:57 pm - 10:40 amORD-PTY

14h 43m1 stop

9:33 pm - 7:54 amPTY-ORD

11h 21m1 stop

$473Multiple Airlines

Find Deal

Fri, Jan 30 - Wed, Feb 4

8:59 am - 7:20 pmORD-PTY

9h 21m1 stop

9:33 pm - 7:54 amPTY-ORD

11h 21m1 stop

$474Multiple Airlines

Find Deal

Sat, Jan 17 - Sat, Jan 24

3:22 pm - 8:35 pmORD-PTY

5h 13mnonstop

7:20 pm - 1:04 amPTY-ORD

5h 44mnonstop

$563Copa Airlines

Find Deal

Thu, Mar 12 - Wed, Mar 18

2:13 pm - 8:35 pmORD-PTY

5h 22mnonstop

7:40 pm - 12:24 amPTY-ORD

5h 44mnonstop

$572Copa Airlines

Find Deal

Thu, Jan 15 - Mon, Jan 19

6:00 am - 12:55 pmMDW-PTY

6h 55m1 stop

2:20 pm - 12:35 pmPTY-MDW

22h 15m2 stops

$582Delta

Find Deal

Tue, Mar 10 - Wed, Mar 11

8:57 pm - 1:21 pmORD-PTY

15h 24m2 stops

1:50 pm - 12:14 amPTY-ORD

10h 24m1 stop

$582American Airlines

Find Deal

Thu, Mar 5 - Tue, Mar 10

6:00 am - 12:55 pmMDW-PTY

6h 55m1 stop

2:20 pm - 4:25 pmPTY-MDW

26h 05m1 stop

$587Delta

Find Deal

Tue, Mar 10 - Wed, Mar 11

Avianca flights from Chicago to Panama City

Our best Avianca deals on Chicago to Panama City flight tickets

Avianca

Feb 5

ORD10:20 pmChicago O'Hare Intl

17h 35m

1 stop

PTY4:55 pmPanama City Tocumen Intl

Feb 7

PTY2:55 amPanama City Tocumen Intl

18h 25m

1 stop

ORD8:20 pmChicago O'Hare Intl

$451

Find similar

Avianca

Feb 11

ORD10:20 pmChicago O'Hare Intl

17h 35m

1 stop

PTY4:55 pmPanama City Tocumen Intl

Feb 14

PTY2:55 amPanama City Tocumen Intl

18h 25m

1 stop

ORD8:20 pmChicago O'Hare Intl

$479

Find similar

Avianca

Nov 16

ORD10:20 pmChicago O'Hare Intl

9h 30m

1 stop

PTY8:50 amPanama City Tocumen Intl

Nov 21

PTY9:45 amPanama City Tocumen Intl

11h 35m

1 stop

ORD8:20 pmChicago O'Hare Intl

$541

Find similar

American Airlines flights from Chicago to Panama City

Our best American Airlines deals on Chicago to Panama City flight tickets

American Airlines

Mar 5

ORD8:57 pmChicago O'Hare Intl

15h 24m

2 stops

PTY1:21 pmPanama City Tocumen Intl

Mar 10

PTY1:50 pmPanama City Tocumen Intl

10h 24m

1 stop

ORD12:14 amChicago O'Hare Intl

$582

Find similar

American Airlines

Nov 20

ORD5:00 amChicago O'Hare Intl

7h 43m

1 stop

PTY1:43 pmPanama City Tocumen Intl

Nov 23

PTY2:43 pmPanama City Tocumen Intl

9h 16m

1 stop

ORD10:59 pmChicago O'Hare Intl

$762

Find similar

American Airlines

Nov 20

ORD8:35 pmChicago O'Hare Intl

16h 08m

2 stops

PTY1:43 pmPanama City Tocumen Intl

Nov 23

PTY2:43 pmPanama City Tocumen Intl

17h 21m

2 stops

ORD7:04 amChicago O'Hare Intl

$881

Find similar

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 2/5

10:20 pm-4:55 pm

1 stop17h 35m

Panama City Tocumen Intl

Sat 2/7

2:55 am-8:20 pm

1 stop18h 25m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/29

6:57 pm-8:06 am

1 stop12h 09m

Panama City Tocumen Intl

Sun 2/8

9:33 pm-7:54 am

1 stop11h 21m

$462

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 1/18

6:57 pm-8:06 am

1 stop12h 09m

Panama City Tocumen Intl

Sun 1/25

9:33 pm-7:54 am

1 stop11h 21m

$465

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 1/30

6:57 pm-10:40 am

1 stop14h 43m

Panama City Tocumen Intl

Wed 2/4

9:33 pm-7:54 am

1 stop11h 21m

$473

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 1/17

8:59 am-7:20 pm

1 stop9h 21m

Panama City Tocumen Intl

Sat 1/24

9:33 pm-7:54 am

1 stop11h 21m

$474

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 3/12

3:22 pm-8:35 pm

Nonstop5h 13m

Panama City Tocumen Intl

Wed 3/18

7:20 pm-1:04 am

Nonstop5h 44m

$563

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/15

2:13 pm-8:35 pm

Nonstop5h 22m

Panama City Tocumen Intl

Mon 1/19

7:40 pm-12:24 am

Nonstop5h 44m

$572

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 3/10

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Wed 3/11

2:20 pm-12:35 pm

2 stops22h 15m

$582

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 3/5

8:57 pm-1:21 pm

2 stops15h 24m

Panama City Tocumen Intl

Tue 3/10

1:50 pm-12:14 am

1 stop10h 24m

$582

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 3/10

6:00 am-12:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Wed 3/11

2:20 pm-4:25 pm

1 stop26h 05m

$587

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Chicago to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

Other information

What is the cheapest month to fly to Panama City?

In general, July is the cheapest month to fly from Chicago to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $523. If you’re not able to fly to Panama City in July, then June is your next best option. Flight prices from Chicago to Panama City during June average around $528.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $533. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $607. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Chicago to Panama City during this time can be as low as $505. Try not to purchase tickets at noon because they tend to be around $592. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago to Panama City Tocumen Intl flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $567 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Chicago for as low as $502 on momondo.

What cabin class options are available on Chicago to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Chicago to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Panama City flights?

You could potentially save up to 57% on your flight if you consider stops on a Chicago to Panama City flight.

How have Chicago to Panama City flight prices changed over time?

When to book flights from Chicago to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Panama City according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Chicago to Panama City (CHI to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Panama City

Best Price Found	$170
Fastest flight time	5h 13m
Direct flights	Every day
Airports in Panama City	1 airport

The best one-way flight to Panama City from Chicago in the past 72 hours is $170. The best round-trip flight deal from Chicago to Panama City found on momondo in the last 72 hours is $463.

The fastest flight from Chicago to Panama City takes 5h 13m

Direct flights go from Chicago to Panama City every day.

There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)

Search flight deals

How far is Chicago to Panama City Tocumen Intl by plane?
The straight-line distance from Chicago to Panama City Tocumen Intl is 2323.9 mi. Typically, this will take 5h 13m by plane in normal conditions.
When did momondo last update prices for flights from Chicago to Panama City Tocumen Intl Airport?
Prices for flights from Chicago to Panama City Tocumen Intl Airport refresh daily.
How many operators does momondo search for flights from Chicago to Panama City Tocumen Intl Airport?
As of November 2025, there are 5 operators available to choose from for flights from Chicago to Panama City Tocumen Intl Airport.
How old do you have to be to fly from Chicago to Panama City Tocumen Intl Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Panama City Tocumen Intl Airport.
What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?
The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular plane model from Chicago to Panama City?
momondo data reveals that the most frequently booked plane model on the route from Chicago to Panama City is Boeing 737-800, representing 40.61% of all bookings. The subsequent popular models are Airbus A320neo at 27.39%, Boeing 737 MAX 8 at 13.45%, and Boeing 737 MAX 9 at 7.52%.
What is the most popular airline from Chicago to Panama City?
momondo data reveals that the most frequently booked airline on the route from Chicago to Panama City is Copa Airlines, representing 73% of all bookings. The subsequent popular airlines are Avianca at 11%, United Airlines at 9%, and Delta at 4%.

Best airlines flying from Chicago to Panama City

Compare and see reviews for airlines that fly from Chicago to Panama City with momondo

Airline	Rating	Free Cancellation	Price
Avianca	PriceFrom $334	Free Cancellation	Rating 6.6 2,473 reviews	Search Avianca flights
Copa Airlines	PriceFrom $464	Free Cancellation	Rating 7.6 1,563 reviews	Search Copa Airlines flights
United Airlines	PriceFrom $479	Free Cancellation	Rating 7.4 9,015 reviews	Search United Airlines flights
Delta	PriceFrom $479	Free Cancellation	Rating 7.9 8,008 reviews	Search Delta flights
American Airlines	PriceFrom $589	Free Cancellation	Rating 7.2 11,050 reviews	Search American Airlines flights

Copa Airlines Flights From Chicago to Panama City
Copa Airlines flies from Chicago to Panama City around 9 times per week, with 1,563 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Chicago to Panama City in the last 72 hours was $464 (round-trip), much lower than the average airfare cost of $577 for Copa Airlines flights on this route.
United Airlines Flights From Chicago to Panama City
United Airlines (7.4/10 from 9,015 reviews) operates around 9 flights from Chicago to Panama City in any given week. The average United Airlines airfare for this route is around $653, with deals from around $479 rare but found on momondo. Referenced prices are for round-trip Chicago to Panama City flight searches in the last 72 hours.

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Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Chicago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Chicago to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Chicago to Panama City.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

An easier way to manage your Panama City trip

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Airports servicing Panama

Puerto Piña Bahia Pinas Airport

Bocas Del Toro Airport

Changuinola Airport

David Enrique Malek Airport

Jaque Airport

Mulatupo Airport

Puerto Obaldia Airport

Playon Chico Airport

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Flights from Chicago Midway to Atlanta Hartsfield-Jackson

Cheap flights from Chicago to Panama City from $207

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Panama City departing on 3/25. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Our best American Airlines deals on Chicago to Panama City flight tickets

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How to get the cheapest flight ticket from Chicago to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

What is the cheapest day to depart on your flight to Panama City?

What is the cheapest time of day to depart on your flight to Panama City?

What is the cheapest Chicago to Panama City Tocumen Intl flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

What cabin class options are available on Chicago to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Chicago to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Panama City flights?

You could potentially save up to 57% on your flight if you consider stops on a Chicago to Panama City flight.

How have Chicago to Panama City flight prices changed over time?

What is the cheapest airline that flies from Chicago to Panama City Tocumen Intl?

Avianca and Aeromexico are the most popular carriers operating from Chicago to Panama City Tocumen Intl

What airlines fly to Panama City?

Which airport is the most popular layover for flights between Chicago and Panama City?

Bogotá (BOG) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Chicago to Panama City?

Flights via Bogotá (BOG) offer the lowest average round-trip price of $440.

Which layover airport has the shortest travel time from Chicago to Panama City?

Flights connecting via Atlanta (ATL) have the shortest average one-way travel time: 7h 02m.

Which layover airport has the shortest connection time from Chicago to Panama City?

Houston (IAH) has the shortest average layover time for this route: 1h 15m.

How many flights depart from Chicago to Panama City on average per day?

The number of flights available between Chicago and Panama City is 3 per day as of November 2025. The most frequent departure time is 2:00PM, with 57% of daily flights leaving in the afternoon.

How many flights depart from Chicago to Panama City on average per week?

As of November 2025, there are 22 flights per week flying from Chicago to Panama City. The most common day of the week flights depart is Mon, with 23% of flights taking off on this day.

When to book flights from Chicago to Panama City

Cheap Chicago to Panama City (CHI to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Panama City

Best Price Found

Fastest flight time

Direct flights

Airports in Panama City

How far is Chicago to Panama City Tocumen Intl by plane?

When did momondo last update prices for flights from Chicago to Panama City Tocumen Intl Airport?

How many operators does momondo search for flights from Chicago to Panama City Tocumen Intl Airport?

How old do you have to be to fly from Chicago to Panama City Tocumen Intl Airport?

What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

What is the most popular plane model from Chicago to Panama City?

What is the most popular airline from Chicago to Panama City?

Best airlines flying from Chicago to Panama City

Compare and see reviews for airlines that fly from Chicago to Panama City with momondo

Copa Airlines Flights From Chicago to Panama City

United Airlines Flights From Chicago to Panama City

Traveling to a place near Panama City?

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

How can momondo help me find flights from Chicago to Panama City?

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Airports servicing Panama