Cheap flights from Chicago to Panama City from $161

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago to Panama City departing on 2/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Cheap round-trip flights

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Multiple Airlines Logo
9:14 am - 7:20 pmORD-PTY
9h 06m1 stop
Multiple Airlines Logo
9:33 pm - 8:09 amPTY-ORD
11h 36m1 stop
$462Multiple Airlines
Find Deal
Sun, Feb 1 - Sun, Feb 8
Multiple Airlines Logo
6:57 pm - 8:06 amORD-PTY
12h 09m1 stop
Multiple Airlines Logo
9:33 pm - 8:09 amPTY-ORD
11h 36m1 stop
$463Multiple Airlines
Find Deal
Sat, Jan 17 - Sat, Jan 24
Multiple Airlines Logo
9:14 am - 8:37 pmORD-PTY
10h 23m1 stop
Multiple Airlines Logo
9:33 pm - 9:16 amPTY-ORD
12h 43m1 stop
$472Multiple Airlines
Find Deal
Wed, Feb 4 - Thu, Feb 12
Multiple Airlines Logo
9:14 am - 7:20 pmORD-PTY
9h 06m1 stop
Multiple Airlines Logo
9:33 pm - 8:09 amPTY-ORD
11h 36m1 stop
$473Multiple Airlines
Find Deal
Thu, Jan 15 - Thu, Jan 22
Multiple Airlines Logo
9:14 am - 7:20 pmORD-PTY
9h 06m1 stop
Multiple Airlines Logo
10:25 am - 6:39 pmPTY-ORD
9h 14m1 stop
$474Multiple Airlines
Find Deal
Thu, Jan 15 - Thu, Jan 29
Multiple Airlines Logo
9:14 am - 8:50 amORD-PTY
22h 36m2 stops
Multiple Airlines Logo
2:55 pm - 8:34 pmPTY-ORD
30h 39m3 stops
$477Multiple Airlines
Find Deal
Thu, Jan 22 - Mon, Jan 26
Multiple Airlines Logo
6:57 pm - 8:06 amORD-PTY
12h 09m1 stop
Multiple Airlines Logo
9:33 pm - 9:16 amPTY-ORD
12h 43m1 stop
$492Multiple Airlines
Find Deal
Thu, Feb 5 - Thu, Feb 12
Multiple Airlines Logo
6:57 pm - 8:06 amORD-PTY
12h 09m1 stop
Multiple Airlines Logo
9:33 pm - 8:09 amPTY-ORD
11h 36m1 stop
$496Multiple Airlines
Find Deal
Fri, Jan 16 - Fri, Jan 23
Delta Logo
6:00 am - 2:02 pmMDW-PTY
7h 02m1 stop
Delta Logo
3:27 pm - 10:44 pmPTY-MDW
8h 17m1 stop
$578Delta
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Sun, Feb 15 - Thu, Feb 19
Delta Logo
6:00 am - 1:55 pmMDW-PTY
6h 55m1 stop
Delta Logo
3:27 pm - 10:44 pmPTY-MDW
8h 17m1 stop
$579Delta
Find Deal
Tue, Feb 3 - Fri, Feb 13

Avianca flights from Chicago to Panama City

Our best Avianca deals on Chicago to Panama City flight tickets
Avianca
Dec 1
ORD10:20 pmChicago O'Hare Intl
9h 30m
1 stop
PTY8:50 amPanama City Tocumen Intl
Dec 4
PTY9:45 amPanama City Tocumen Intl
11h 35m
1 stop
ORD8:20 pmChicago O'Hare Intl
Avianca
May 5
ORD2:35 pmChicago O'Hare Intl
19h 35m
1 stop
PTY10:10 amPanama City Tocumen Intl
May 8
PTY3:25 amPanama City Tocumen Intl
9h 50m
1 stop
ORD1:15 pmChicago O'Hare Intl
Avianca
Dec 1
ORD10:20 pmChicago O'Hare Intl
17h 35m
1 stop
PTY4:55 pmPanama City Tocumen Intl
Dec 5
PTY2:55 amPanama City Tocumen Intl
18h 25m
1 stop
ORD8:20 pmChicago O'Hare Intl

Delta flights from Chicago to Panama City

Our best Delta deals on Chicago to Panama City flight tickets
Delta
Feb 15
MDW6:00 amChicago Midway
7h 02m
1 stop
PTY2:02 pmPanama City Tocumen Intl
Feb 19
PTY3:27 pmPanama City Tocumen Intl
8h 17m
1 stop
MDW10:44 pmChicago Midway
Delta
Feb 3
MDW6:00 amChicago Midway
6h 55m
1 stop
PTY1:55 pmPanama City Tocumen Intl
Feb 13
PTY3:27 pmPanama City Tocumen Intl
8h 17m
1 stop
MDW10:44 pmChicago Midway
Delta
Mar 10
MDW6:00 amChicago Midway
6h 55m
1 stop
PTY12:55 pmPanama City Tocumen Intl
Mar 11
PTY2:20 pmPanama City Tocumen Intl
28h 14m
2 stops
MDW6:34 pmChicago Midway

momondo Fare Finder

 
Customize your flight search to find flights from Chicago to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 18, 2025.
Use the filters below to find and compare flights from Chicago to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 2/1

9:14 am-7:20 pm

1 stop9h 06m

Panama City Tocumen Intl

Sun 2/8

9:33 pm-8:09 am

1 stop11h 36m

$462

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 1/17

6:57 pm-8:06 am

1 stop12h 09m

Panama City Tocumen Intl

Sat 1/24

9:33 pm-8:09 am

1 stop11h 36m

$463

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 2/4

9:14 am-8:37 pm

1 stop10h 23m

Panama City Tocumen Intl

Thu 2/12

9:33 pm-9:16 am

1 stop12h 43m

$472

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/15

9:14 am-7:20 pm

1 stop9h 06m

Panama City Tocumen Intl

Thu 1/22

9:33 pm-8:09 am

1 stop11h 36m

$473

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/15

9:14 am-7:20 pm

1 stop9h 06m

Panama City Tocumen Intl

Thu 1/29

10:25 am-6:39 pm

1 stop9h 14m

$474

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/22

9:14 am-8:50 am

2 stops22h 36m

Panama City Tocumen Intl

Mon 1/26

2:55 pm-8:34 pm

3 stops30h 39m

$477

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 2/5

6:57 pm-8:06 am

1 stop12h 09m

Panama City Tocumen Intl

Thu 2/12

9:33 pm-9:16 am

1 stop12h 43m

$492

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 1/16

6:57 pm-8:06 am

1 stop12h 09m

Panama City Tocumen Intl

Fri 1/23

9:33 pm-8:09 am

1 stop11h 36m

$496

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Sun 2/15

6:00 am-2:02 pm

1 stop7h 02m

Panama City Tocumen Intl

Thu 2/19

3:27 pm-10:44 pm

1 stop8h 17m

$578

ChicagoPanama City

MDW - PTY

MDWPTY

Chicago Midway

Tue 2/3

6:00 am-1:55 pm

1 stop6h 55m

Panama City Tocumen Intl

Fri 2/13

3:27 pm-10:44 pm

1 stop8h 17m

$579

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Chicago to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Chicago and Panama City?

What is the cheapest month to fly to Panama City?

In general, July is the cheapest month to fly from Chicago to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $523. If you’re not able to fly to Panama City in July, then June is your next best option. Flight prices from Chicago to Panama City during June average around $528.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $533. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $607. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Chicago to Panama City during this time can be as low as $505. Try not to purchase tickets at noon because they tend to be around $592. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago to Panama City Tocumen Intl flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Chicago when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $566 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Chicago for as low as $516 on momondo.

What cabin class options are available on Chicago to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Chicago to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago to Panama City flights?

You could potentially save up to 57% on your flight if you consider stops on a Chicago to Panama City flight.

How have Chicago to Panama City flight prices changed over time?

When to book flights from Chicago to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago to Panama City (CHI to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago to Panama City

Best Price Found

$170

Fastest flight time

5h 13m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Chicago in the past 72 hours is $170. The best round-trip flight deal from Chicago to Panama City found on momondo in the last 72 hours is $463.
The fastest flight from Chicago to Panama City takes 5h 13m
Direct flights go from Chicago to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
  • How far is Chicago to Panama City Tocumen Intl by plane?

    The straight-line distance from Chicago to Panama City Tocumen Intl is 2323.9 mi. Typically, this will take 5h 26m by plane in normal conditions.

  • When did momondo last update prices for flights from Chicago to Panama City Tocumen Intl Airport?

    Prices for flights from Chicago to Panama City Tocumen Intl Airport refresh daily.

  • How many operators does momondo search for flights from Chicago to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Chicago to Panama City Tocumen Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Chicago to Panama City?

  • What is the most popular airline from Chicago to Panama City?

Best airlines flying from Chicago to Panama City

Compare and see reviews for airlines that fly from Chicago to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $334Free CancellationRating
6.6
2,475 reviews
Search Avianca flights
Copa AirlinesPriceFrom $464Free CancellationRating
7.6
1,566 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $479Free CancellationRating
7.4
9,015 reviews
Search United Airlines flights
DeltaPriceFrom $479Free CancellationRating
7.9
8,007 reviews
Search Delta flights
American AirlinesPriceFrom $589Free CancellationRating
7.2
11,047 reviews
Search American Airlines flights
  • Copa Airlines Flights From Chicago to Panama City

    Copa Airlines flies from Chicago to Panama City around 4 times per week, with 1,566 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Chicago to Panama City in the last 72 hours was $464 (round-trip), much lower than the average airfare cost of $577 for Copa Airlines flights on this route.

  • United Airlines Flights From Chicago to Panama City

    United Airlines (7.4/10 from 9,015 reviews) operates around 4 flights from Chicago to Panama City in any given week. The average United Airlines airfare for this route is around $653, with deals from around $479 rare but found on momondo. Referenced prices are for round-trip Chicago to Panama City flight searches in the last 72 hours.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

Yes. All flights to Panama City from Chicago on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Chicago to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Chicago to Panama City.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Price alerts on flights to Panama City from Chicago are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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1 adult
Thu 12/18
Thu 12/25

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