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Cheap flights from Charleston to Panama from $258

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Panama departing on 8/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charleston to Panama

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:00 am - 6:37 pm
CHS
-
PTY
12h 37m
1 stop
United Airlines Logo
9:45 am - 11:59 pm
PTY
-
CHS
13h 14m
1 stop
$557United Airlines
Wed, Sep 16 - Mon, Sep 21
Multiple Airlines Logo
8:14 pm - 10:30 am
CHS
-
PTY
15h 16m
2 stops
Multiple Airlines Logo
3:50 pm - 10:08 am
PTY
-
CHS
17h 18m
2 stops
$559Multiple Airlines
Thu, Aug 27 - Sun, Aug 30
United Airlines Logo
7:00 am - 6:37 pm
CHS
-
PTY
12h 37m
1 stop
United Airlines Logo
3:30 pm - 1:58 pm
PTY
-
CHS
21h 28m
2 stops
$561United Airlines
Wed, Sep 16 - Mon, Sep 21
Multiple Airlines Logo
8:14 pm - 10:30 am
CHS
-
PTY
15h 16m
2 stops
Multiple Airlines Logo
11:25 am - 10:08 am
PTY
-
CHS
21h 43m
3 stops
$566Multiple Airlines
Thu, Aug 27 - Sun, Aug 30
United Airlines Logo
7:00 am - 6:37 pm
CHS
-
PTY
12h 37m
1 stop
United Airlines Logo
9:45 am - 11:59 pm
PTY
-
CHS
13h 14m
1 stop
$569United Airlines
Thu, Sep 3 - Mon, Sep 14
United Airlines Logo
6:30 am - 4:04 am
CHS
-
PTY
22h 34m
2 stops
United Airlines Logo
9:45 am - 10:41 am
PTY
-
CHS
23h 56m
2 stops
$573United Airlines
Thu, Sep 3 - Tue, Sep 15
Multiple Airlines Logo
8:25 pm - 2:55 pm
CHS
-
PTY
19h 30m
3 stops
Multiple Airlines Logo
3:50 pm - 10:08 am
PTY
-
CHS
17h 18m
2 stops
$576Multiple Airlines
Fri, Aug 21 - Mon, Aug 24
American Airlines Logo
6:00 am - 12:16 pm
CHS
-
PTY
7h 16m
1 stop
American Airlines Logo
1:16 pm - 9:36 pm
PTY
-
CHS
7h 20m
1 stop
$577American Airlines
Fri, Sep 25 - Tue, Sep 29
Multiple Airlines Logo
11:05 am - 10:30 am
CHS
-
PTY
24h 25m
2 stops
Multiple Airlines Logo
3:50 pm - 10:15 am
PTY
-
CHS
17h 25m
2 stops
$578Multiple Airlines
Fri, Sep 25 - Tue, Sep 29
United Airlines Logo
7:00 am - 7:31 pm
CHS
-
PTY
13h 31m
1 stop
United Airlines Logo
11:35 am - 4:12 pm
PTY
-
CHS
28h 37m
1 stop
$579United Airlines
Tue, Aug 18 - Thu, Feb 25

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American Airlines flights from Charleston to Panama

Our best American Airlines deals on Charleston to Panama flight tickets
American Airlines
Sep 25
CHS6:00 amCharleston
7h 16m
1 stop
PTY12:16 pmPanama City Tocumen Intl
Sep 29
PTY1:16 pmPanama City Tocumen Intl
7h 20m
1 stop
CHS9:36 pmCharleston
$577
American Airlines
Aug 18
CHS2:06 pmCharleston
23h 33m
2 stops
PTY12:39 pmPanama City Tocumen Intl
Feb 25
PTY2:39 pmPanama City Tocumen Intl
9h 20m
1 stop
CHS11:59 pmCharleston
$583
American Airlines
Sep 9
CHS7:00 amCharleston
6h 26m
1 stop
PTY12:26 pmPanama City Tocumen Intl
Sep 11
PTY1:16 pmPanama City Tocumen Intl
20h 32m
2 stops
CHS10:48 amCharleston
$586

United Airlines flights from Charleston to Panama

Our best United Airlines deals on Charleston to Panama flight tickets
United Airlines
Sep 16
CHS7:00 amCharleston
12h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Sep 21
PTY9:45 amPanama City Tocumen Intl
13h 14m
1 stop
CHS11:59 pmCharleston
$557
United Airlines
Sep 16
CHS7:00 amCharleston
12h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Sep 21
PTY3:30 pmPanama City Tocumen Intl
21h 28m
2 stops
CHS1:58 pmCharleston
$561
United Airlines
Sep 3
CHS7:00 amCharleston
12h 37m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Sep 14
PTY9:45 amPanama City Tocumen Intl
13h 14m
1 stop
CHS11:59 pmCharleston
$569

momondo Fare Finder

 
Customize your flight search to find flights from Charleston to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 25, 2026.
Use the filters below to find and compare flights from Charleston to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 9/16

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Mon 9/21

9:45 am-11:59 pm

1 stop13h 14m

$557

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 8/27

8:14 pm-10:30 am

2 stops15h 16m

Panama City Tocumen Intl

Sun 8/30

3:50 pm-10:08 am

2 stops17h 18m

$559

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 9/16

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Mon 9/21

3:30 pm-1:58 pm

2 stops21h 28m

$561

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 8/27

8:14 pm-10:30 am

2 stops15h 16m

Panama City Tocumen Intl

Sun 8/30

11:25 am-10:08 am

3 stops21h 43m

$566

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 9/3

7:00 am-6:37 pm

1 stop12h 37m

Panama City Tocumen Intl

Mon 9/14

9:45 am-11:59 pm

1 stop13h 14m

$569

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Thu 9/3

6:30 am-4:04 am

2 stops22h 34m

Panama City Tocumen Intl

Tue 9/15

9:45 am-10:41 am

2 stops23h 56m

$573

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 8/21

8:25 pm-2:55 pm

3 stops19h 30m

Panama City Tocumen Intl

Mon 8/24

3:50 pm-10:08 am

2 stops17h 18m

$576
Quickest round-trip

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 9/25

6:00 am-12:16 pm

1 stop7h 16m

Panama City Tocumen Intl

Tue 9/29

1:16 pm-9:36 pm

1 stop7h 20m

$577

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 9/25

11:05 am-10:30 am

2 stops24h 25m

Panama City Tocumen Intl

Tue 9/29

3:50 pm-10:15 am

2 stops17h 25m

$578

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 8/18

7:00 am-7:31 pm

1 stop13h 31m

Panama City Tocumen Intl

Thu 2/25

11:35 am-4:12 pm

1 stop28h 37m

$579

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 12 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Charleston to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of August is, on average, the cheapest month to fly to Panama from Charleston, with most prices found around $458. If you don’t want to visit Panama in August, then you should wait until March to fly from Charleston, when ticket prices are also cheap, with an average price of $487.

Cheap Charleston to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama

Fastest flight time

9h 03m

Direct flights

None
The fastest flight from Charleston to Panama takes 9h 03m
There are no direct flights from Charleston to Panama. There are no popular flight routes from Charleston to Panama.
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Frequently asked questions about flying from Charleston to Panama

  • When did momondo last update prices for flights from Charleston Airport to Panama?

    Prices for flights from Charleston Airport to Panama are updated daily.

  • How many operators does momondo search for flights from Charleston Airport to Panama?

  • How old do you have to be to fly from Charleston Airport to Panama?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama.

  • What documentation or ID do you need to fly to Panama?

    The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Charleston to Panama

Compare and see reviews for airlines that fly from Charleston to Panama with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $369Free CancellationRating
7.4
10,034 reviews
Search United Airlines flights
DeltaPriceFrom $396Free CancellationRating
7.8
8,486 reviews
Search Delta flights
American AirlinesPriceFrom $399Free CancellationRating
7.1
11,847 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Panama?

It is quick and easy to find Charleston to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Charleston to Panama with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama from Charleston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Charleston to Panama?

Once you have performed a search for Charleston to Panama flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Charleston to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Charleston. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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