What is the cheapest airline that flies from Charleston to Panama?

American Airlines and United Airlines are the most popular carriers operating from Charleston to Panama

What airlines fly to Panama?

American Airlines, United Airlines and Delta are the top three most popular airlines that fly to Panama from Charleston according to our data. American Airlines is the first choice among our users, with 49% of people opting to fly with this airline when traveling to Panama. Keep in mind that there are 3 different airlines that fly to Panama on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Charleston Airport to Panama?

Prices for flights from Charleston Airport to Panama are updated daily.

How many operators does momondo search for flights from Charleston Airport to Panama?

As of April 2026, there are 3 operators available to choose from for flights from Charleston Airport to Panama.

How old do you have to be to fly from Charleston Airport to Panama?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama.

What documentation or ID do you need to fly to Panama?

The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

$218 Cheap Flights from Charleston to Panama in 2026

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Charleston to Panama

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

6:30 am - 12:56 pm

CHS

PTY

7h 26m

1 stop

2:21 pm - 8:40 am

PTY

CHS

17h 19m

1 stop

$467Delta

Mon, Sep 28 - Tue, Oct 6

10:19 am - 7:31 pm

CHS

PTY

10h 12m

2 stops

10:00 am - 10:02 am

PTY

CHS

23h 02m

2 stops

$471United Airlines

Mon, Sep 28 - Mon, Oct 5

7:59 pm - 12:56 pm

CHS

PTY

17h 57m

1 stop

2:21 pm - 11:57 pm

PTY

CHS

8h 36m

1 stop

$474Delta

Sun, Sep 27 - Mon, Oct 5

7:59 pm - 12:56 pm

CHS

PTY

17h 57m

1 stop

2:21 pm - 4:51 pm

PTY

CHS

25h 30m

1 stop

$480Delta

Sun, Sep 27 - Thu, Oct 8

5:30 am - 12:56 pm

CHS

PTY

8h 26m

1 stop

2:21 pm - 11:57 pm

PTY

CHS

8h 36m

1 stop

$501Delta

Fri, Oct 2 - Mon, Oct 5

6:00 am - 7:31 pm

CHS

PTY

14h 31m

2 stops

10:00 am - 10:12 pm

PTY

CHS

11h 12m

1 stop

$505United Airlines

Sat, Oct 3 - Wed, Oct 7

11:18 am - 7:31 pm

CHS

PTY

9h 13m

1 stop

3:30 pm - 10:08 am

PTY

CHS

17h 38m

2 stops

$508United Airlines

Fri, May 29 - Mon, Jun 8

7:34 pm - 12:14 pm

CHS

PTY

17h 40m

1 stop

1:14 pm - 11:59 pm

PTY

CHS

9h 45m

1 stop

$510American Airlines

Tue, May 26 - Tue, Jun 2

11:09 am - 7:31 pm

CHS

PTY

9h 22m

1 stop

3:30 pm - 10:12 pm

PTY

CHS

29h 42m

1 stop

$511United Airlines

Wed, Sep 30 - Sat, Oct 3

6:50 am - 4:12 pm

CHS

PTY

10h 22m

1 stop

10:00 am - 10:15 pm

PTY

CHS

11h 15m

1 stop

$514United Airlines

Fri, Jul 3 - Wed, Jul 8

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American Airlines flights from Charleston to Panama

Our best American Airlines deals on Charleston to Panama flight tickets

American Airlines

May 26

CHS7:34 pmCharleston

17h 40m

1 stop

PTY12:14 pmPanama City Tocumen Intl

Jun 2

PTY1:14 pmPanama City Tocumen Intl

9h 45m

1 stop

CHS11:59 pmCharleston

$510

American Airlines

May 14

CHS7:13 pmCharleston

18h 33m

2 stops

PTY12:46 pmPanama City Tocumen Intl

May 17

PTY1:49 pmPanama City Tocumen Intl

19h 45m

1 stop

CHS10:34 amCharleston

$540

American Airlines

Jul 24

CHS7:50 pmCharleston

17h 24m

2 stops

PTY12:14 pmPanama City Tocumen Intl

Aug 2

PTY1:14 pmPanama City Tocumen Intl

22h 05m

2 stops

CHS12:19 pmCharleston

$550

Delta flights from Charleston to Panama

Our best Delta deals on Charleston to Panama flight tickets

Delta

Sep 28

CHS6:30 amCharleston

7h 26m

1 stop

PTY12:56 pmPanama City Tocumen Intl

Oct 6

PTY2:21 pmPanama City Tocumen Intl

17h 19m

1 stop

CHS8:40 amCharleston

$467

Delta

Sep 27

CHS7:59 pmCharleston

17h 57m

1 stop

PTY12:56 pmPanama City Tocumen Intl

Oct 5

PTY2:21 pmPanama City Tocumen Intl

8h 36m

1 stop

CHS11:57 pmCharleston

$474

Delta

Sep 27

CHS7:59 pmCharleston

17h 57m

1 stop

PTY12:56 pmPanama City Tocumen Intl

Oct 8

PTY2:21 pmPanama City Tocumen Intl

25h 30m

1 stop

CHS4:51 pmCharleston

$480

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 9/28

6:30 am-12:56 pm

1 stop7h 26m

Panama City Tocumen Intl

Tue 10/6

2:21 pm-8:40 am

1 stop17h 19m

$467

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Mon 9/28

10:19 am-7:31 pm

2 stops10h 12m

Panama City Tocumen Intl

Mon 10/5

10:00 am-10:02 am

2 stops23h 02m

$471

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sun 9/27

7:59 pm-12:56 pm

1 stop17h 57m

Panama City Tocumen Intl

Mon 10/5

2:21 pm-11:57 pm

1 stop8h 36m

$474

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sun 9/27

7:59 pm-12:56 pm

1 stop17h 57m

Panama City Tocumen Intl

Thu 10/8

2:21 pm-4:51 pm

1 stop25h 30m

$480

Quickest round-trip

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 10/2

5:30 am-12:56 pm

1 stop8h 26m

Panama City Tocumen Intl

Mon 10/5

2:21 pm-11:57 pm

1 stop8h 36m

$501

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Sat 10/3

6:00 am-7:31 pm

2 stops14h 31m

Panama City Tocumen Intl

Wed 10/7

10:00 am-10:12 pm

1 stop11h 12m

$505

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 5/29

11:18 am-7:31 pm

1 stop9h 13m

Panama City Tocumen Intl

Mon 6/8

3:30 pm-10:08 am

2 stops17h 38m

$508

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Tue 5/26

7:34 pm-12:14 pm

1 stop17h 40m

Panama City Tocumen Intl

Tue 6/2

1:14 pm-11:59 pm

1 stop9h 45m

$510

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Wed 9/30

11:09 am-7:31 pm

1 stop9h 22m

Panama City Tocumen Intl

Sat 10/3

3:30 pm-10:12 pm

1 stop29h 42m

$511

CharlestonPanama City

CHS - PTY

CHSPTY

Charleston

Fri 7/3

6:50 am-4:12 pm

1 stop10h 22m

Panama City Tocumen Intl

Wed 7/8

10:00 am-10:15 pm

1 stop11h 15m

$514

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first

How to get the cheapest flight ticket from Charleston to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Panama?

The month of September is, on average, the cheapest month to fly to Panama from Charleston, with most prices found around $389. If you don’t want to visit Panama in September, then you should wait until August to fly from Charleston, when ticket prices are also cheap, with an average price of $457.

Can stopping save me money on Charleston to Panama flights?

You could potentially save up to 75% on your flight if you consider stops on a Charleston to Panama flight.

Cheap Charleston to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama

Fastest flight time	7h 43m
Direct flights	None

The fastest flight from Charleston to Panama takes 7h 43m

There are no direct flights from Charleston to Panama. There are no popular flight routes from Charleston to Panama.

Search flight deals

Frequently asked questions about flying from Charleston to Panama

When did momondo last update prices for flights from Charleston Airport to Panama?
Prices for flights from Charleston Airport to Panama are updated daily.
How many operators does momondo search for flights from Charleston Airport to Panama?
As of April 2026, there are 3 operators available to choose from for flights from Charleston Airport to Panama.
How old do you have to be to fly from Charleston Airport to Panama?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Charleston Airport to Panama.
What documentation or ID do you need to fly to Panama?
The travel and health documents you'll need for your trip to Panama may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Best airlines flying from Charleston to Panama

Compare and see reviews for airlines that fly from Charleston to Panama with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $309	Free Cancellation	Rating 7.9 8,422 reviews	Search Delta flights
American Airlines	PriceFrom $363	Free Cancellation	Rating 7.1 11,620 reviews	Search American Airlines flights
United Airlines	PriceFrom $389	Free Cancellation	Rating 7.4 9,604 reviews	Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Charleston to Panama?

It is quick and easy to find Charleston to Panama flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Panama that suits you.

Can I find flights from Charleston to Panama with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama from Charleston which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Charleston to Panama?

Once you have performed a search for Charleston to Panama flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Charleston to Panama right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Panama from Charleston. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Popular cities in Panama

Flights to Panama Cityfrom $341

Flights to Bocas del Torofrom $716

Flights to Davidfrom $460

Flights to Changuinola

Cheap flights from Charleston to Panama from $218

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Charleston to Panama departing on 5/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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American Airlines flights from Charleston to Panama

Our best American Airlines deals on Charleston to Panama flight tickets

Delta flights from Charleston to Panama

Our best Delta deals on Charleston to Panama flight tickets

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See travel insights to Panama from

How to get the cheapest flight ticket from Charleston to Panama

What is the cheapest month to fly to Panama?

Can stopping save me money on Charleston to Panama flights?

What is the cheapest airline that flies from Charleston to Panama?

What airlines fly to Panama?

Cheap Charleston to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Charleston to Panama

Fastest flight time

Direct flights

Frequently asked questions about flying from Charleston to Panama

Best airlines flying from Charleston to Panama

Compare and see reviews for airlines that fly from Charleston to Panama with momondo

Why use momondo?

An easier way to manage your Panama trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Panama

Popular cities in Panama

Popular flights according to clicks in the last 7 days on momondo

Charleston flight routes

According to popular flight searches on momondo this year

Panama flight routes

According to popular flight searches on momondo this year

Fly your favorite airline to Panama

Airlines are sorted and displayed according to clicks in the past 7 days on momondo

Cabin classes currently available on flights to Panama

List of cabin classes available on flights landing in Panama. Availability may vary depending on flight origin and airline.

Complete your trip to Panama

Explore popular destinations other users love

According to popular flight searches on momondo this year