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Cheap flights from Tampa to Santiago de los Caballeros from $170

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Santiago de los Caballeros departing on 5/1. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Tampa to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
6:46 pm - 1:49 am
TPA
-
STI
7h 03m
1 stop
Spirit Airlines Logo
3:28 pm - 7:19 am
STI
-
TPA
15h 51m
1 stop
$346Spirit Airlines
Fri, Apr 10 - Mon, Apr 13
Spirit Airlines Logo
10:54 pm - 2:23 pm
TPA
-
STI
15h 29m
1 stop
Spirit Airlines Logo
2:46 am - 7:19 am
STI
-
TPA
4h 33m
1 stop
$367Spirit Airlines
Thu, Apr 9 - Sat, Apr 11
Spirit Airlines Logo
10:54 pm - 2:23 pm
TPA
-
STI
15h 29m
1 stop
Spirit Airlines Logo
3:07 pm - 7:36 pm
STI
-
TPA
4h 29m
1 stop
$376Spirit Airlines
Sat, Apr 11 - Sat, Apr 18
Spirit Airlines Logo
7:20 am - 2:02 pm
TPA
-
STI
6h 42m
1 stop
Spirit Airlines Logo
3:07 pm - 10:11 pm
STI
-
TPA
7h 04m
1 stop
$377Spirit Airlines
Thu, May 7 - Mon, May 11
Spirit Airlines Logo
8:44 am - 2:02 pm
TPA
-
STI
5h 18m
1 stop
Spirit Airlines Logo
3:07 pm - 10:11 pm
STI
-
TPA
7h 04m
1 stop
$378Spirit Airlines
Sat, May 9 - Mon, May 11
Spirit Airlines Logo
7:20 am - 2:02 pm
TPA
-
STI
6h 42m
1 stop
Spirit Airlines Logo
3:07 pm - 10:11 pm
STI
-
TPA
7h 04m
1 stop
$379Spirit Airlines
Thu, May 7 - Thu, May 14
Spirit Airlines Logo
6:46 pm - 1:49 am
TPA
-
STI
7h 03m
1 stop
Spirit Airlines Logo
3:28 pm - 9:59 pm
STI
-
TPA
6h 31m
1 stop
$383Spirit Airlines
Mon, Apr 6 - Thu, Apr 9
Spirit Airlines Logo
10:10 am - 2:02 pm
TPA
-
STI
27h 52m
1 stop
Spirit Airlines Logo
3:07 pm - 9:05 am
STI
-
TPA
17h 58m
1 stop
$384Spirit Airlines
Wed, May 6 - Mon, May 11
Spirit Airlines Logo
10:54 pm - 2:23 pm
TPA
-
STI
15h 29m
1 stop
Spirit Airlines Logo
3:28 pm - 9:59 pm
STI
-
TPA
6h 31m
1 stop
$387Spirit Airlines
Tue, Apr 7 - Sat, Apr 11
Spirit Airlines Logo
8:14 am - 2:23 pm
TPA
-
STI
6h 09m
1 stop
Spirit Airlines Logo
3:28 pm - 9:59 pm
STI
-
TPA
6h 31m
1 stop
$388Spirit Airlines
Sun, Apr 5 - Wed, Apr 8

Delta flights from Tampa to Santiago de los Caballeros

Our best Delta deals on Tampa to Santiago de los Caballeros flight tickets
Delta
Apr 24
TPA12:35 pmTampa
11h 47m
1 stop
STI12:22 amSantiago de los Caballeros
Apr 28
STI1:35 pmSantiago de los Caballeros
9h 42m
1 stop
TPA11:17 pmTampa
$549
Delta
Apr 9
TPA8:35 amTampa
15h 19m
2 stops
STI11:54 pmSantiago de los Caballeros
Apr 12
STI6:00 amSantiago de los Caballeros
17h 12m
1 stop
TPA11:12 pmTampa
$553
Delta
Mar 29
TPA5:30 amTampa
13h 45m
2 stops
STI7:15 pmSantiago de los Caballeros
Apr 6
STI8:40 pmSantiago de los Caballeros
13h 49m
1 stop
TPA10:29 amTampa
$595

JetBlue flights from Tampa to Santiago de los Caballeros

Our best JetBlue deals on Tampa to Santiago de los Caballeros flight tickets
JetBlue
May 9
TPA5:48 pmTampa
21h 24m
1 stop
STI3:12 pmSantiago de los Caballeros
May 11
STI8:57 amSantiago de los Caballeros
13h 06m
1 stop
TPA10:03 pmTampa
$500
JetBlue
Apr 24
TPA6:30 pmTampa
20h 42m
1 stop
STI3:12 pmSantiago de los Caballeros
Apr 29
STI8:31 amSantiago de los Caballeros
13h 32m
1 stop
TPA10:03 pmTampa
$531
JetBlue
May 5
TPA7:00 amTampa
25h 51m
1 stop
STI8:51 amSantiago de los Caballeros
Jun 2
STI7:21 pmSantiago de los Caballeros
25h 48m
1 stop
TPA9:09 pmTampa
$532

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Tampa to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Fri 4/10

6:46 pm-1:49 am

1 stop7h 03m

Santiago de los Caballeros

Mon 4/13

3:28 pm-7:19 am

1 stop15h 51m

$346

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Thu 4/9

10:54 pm-2:23 pm

1 stop15h 29m

Santiago de los Caballeros

Sat 4/11

2:46 am-7:19 am

1 stop4h 33m

$367

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sat 4/11

10:54 pm-2:23 pm

1 stop15h 29m

Santiago de los Caballeros

Sat 4/18

3:07 pm-7:36 pm

1 stop4h 29m

$376

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Thu 5/7

7:20 am-2:02 pm

1 stop6h 42m

Santiago de los Caballeros

Mon 5/11

3:07 pm-10:11 pm

1 stop7h 04m

$377
Quickest round-trip

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sat 5/9

8:44 am-2:02 pm

1 stop5h 18m

Santiago de los Caballeros

Mon 5/11

3:07 pm-10:11 pm

1 stop7h 04m

$378

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Thu 5/7

7:20 am-2:02 pm

1 stop6h 42m

Santiago de los Caballeros

Thu 5/14

3:07 pm-10:11 pm

1 stop7h 04m

$379

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Mon 4/6

6:46 pm-1:49 am

1 stop7h 03m

Santiago de los Caballeros

Thu 4/9

3:28 pm-9:59 pm

1 stop6h 31m

$383

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Wed 5/6

10:10 am-2:02 pm

1 stop27h 52m

Santiago de los Caballeros

Mon 5/11

3:07 pm-9:05 am

1 stop17h 58m

$384

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Tue 4/7

10:54 pm-2:23 pm

1 stop15h 29m

Santiago de los Caballeros

Sat 4/11

3:28 pm-9:59 pm

1 stop6h 31m

$387

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sun 4/5

8:14 am-2:23 pm

1 stop6h 09m

Santiago de los Caballeros

Wed 4/8

3:28 pm-9:59 pm

1 stop6h 31m

$388

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Tampa to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Tampa and Santiago de los Caballeros?

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Tampa is in January. Flight prices, which tend to average around $354, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of January, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $370.

How far in advance should I book a flight to Santiago de los Caballeros?

You are more likely to see cheaper flights to Santiago de los Caballeros from Tampa when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago de los Caballeros for around $496 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago de los Caballeros from Tampa for as low as $387 on momondo.

How have Tampa to Santiago de los Caballeros flight prices changed over time?

As of March 2026, prices for Tampa to Santiago de los Caballeros flights are approximately 69% more expensive when compared to flights at the same time last year.

When to book flights from Tampa to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Santiago de los Caballeros (TPA to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Santiago de los Caballeros

Fastest flight time

3h 36m

Direct flights

None
The fastest flight from Tampa to Santiago de los Caballeros takes 3h 36m
There are no direct flights from Tampa to Santiago de los Caballeros. There are no popular flight routes from Tampa to Santiago de los Caballeros.
Search flight deals

  • How far is Tampa to Santiago de los Caballeros by plane?

    Santiago de los Caballeros is 946.3 mi away from Tampa. A reasonable flight in good conditions will take 3h 36m.

  • When did momondo last update prices for flights from Tampa Airport to Santiago de los Caballeros Airport?

    Prices for flights from Tampa Airport to Santiago de los Caballeros Airport refresh daily.

  • How many operators does momondo search for flights from Tampa Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Tampa Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents required for your trip to Santiago de los Caballeros Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago de los Caballeros Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Tampa to Santiago de los Caballeros?

Best airlines flying from Tampa to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Tampa to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $171Free CancellationRating
7.9
8,345 reviews
Search Delta flights
Spirit AirlinesPriceFrom $272Free CancellationRating
6.3
8,550 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $370Free CancellationRating
7.1
11,510 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Tampa.

Can I find flights from Tampa to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago de los Caballeros from Tampa with this policy.

How can momondo help me find flights from Tampa to Santiago de los Caballeros?

momondo provides multiple filters to help you find the best flight to Santiago de los Caballeros from Tampa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Tampa to Santiago de los Caballeros right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago de los Caballeros, momondo offers a useful price alert feature which will track prices for flights to Santiago de los Caballeros from Tampa and alert you when they change.

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