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Cheap flights from Tampa to Santiago de los Caballeros from $174

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Tampa to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:00 am - 4:08 pmTPA  Tampa-STI Santiago de los Caballeros
8h 08m1 stop Miami
American Airlines Logo
5:36 pm - 9:53 amSTI  Santiago de los Caballeros-TPA Tampa
17h 17m1 stop Philadelphia
$382American Airlines
Fri, Nov 13 - Thu, Nov 19
American Airlines Logo
10:10 am - 2:12 pmTPA  Tampa-STI Santiago de los Caballeros
4h 02m1 stop Miami
American Airlines Logo
3:12 pm - 9:46 amSTI  Santiago de los Caballeros-TPA Tampa
18h 34m2 stops Miami Charlotte Douglas
$387American Airlines
Tue, Oct 13 - Wed, Oct 21
American Airlines Logo
6:00 am - 2:12 pmTPA  Tampa-STI Santiago de los Caballeros
8h 12m2 stops Charlotte Douglas Miami
American Airlines Logo
3:12 pm - 12:35 amSTI  Santiago de los Caballeros-TPA Tampa
9h 23m2 stops Miami Charlotte Douglas
$387American Airlines
Tue, Oct 13 - Wed, Oct 21
American Airlines Logo
7:06 am - 4:36 pmTPA  Tampa-STI Santiago de los Caballeros
8h 30m1 stop Philadelphia
American Airlines Logo
5:08 pm - 11:39 amSTI  Santiago de los Caballeros-TPA Tampa
19h 31m2 stops Miami Charlotte Douglas
$387American Airlines
Tue, Nov 24 - Tue, Dec 1
Frontier Logo
4:45 pm - 10:28 amTPA  Tampa-STI Santiago de los Caballeros
17h 43m1 stop Philadelphia
Frontier Logo
11:43 am - 8:49 amSTI  Santiago de los Caballeros-TPA Tampa
21h 06m1 stop Philadelphia
$415Frontier
Fri, Oct 16 - Sat, Oct 24
JetBlue Logo
7:45 am - 3:23 pmTPA  Tampa-STI Santiago de los Caballeros
6h 38m1 stop Fort Lauderdale
JetBlue Logo
5:01 am - 11:20 amSTI  Santiago de los Caballeros-TPA Tampa
7h 19m1 stop Fort Lauderdale
$435JetBlue
Fri, Nov 13 - Thu, Nov 19
JetBlue Logo
7:45 am - 3:23 pmTPA  Tampa-STI Santiago de los Caballeros
6h 38m1 stop Fort Lauderdale
JetBlue Logo
9:12 am - 2:03 pmSTI  Santiago de los Caballeros-TPA Tampa
5h 51m1 stop Fort Lauderdale
$435JetBlue
Wed, Nov 4 - Mon, Nov 9
Copa Airlines Logo
4:51 am - 2:54 pmTPA  Tampa-STI Santiago de los Caballeros
9h 03m1 stop Panama City Tocumen Intl
Copa Airlines Logo
4:01 pm - 12:40 pmSTI  Santiago de los Caballeros-TPA Tampa
21h 39m1 stop Panama City Tocumen Intl
$455Copa Airlines
Wed, Nov 4 - Mon, Nov 9
United Airlines Logo
10:46 am - 11:51 pmTPA  Tampa-STI Santiago de los Caballeros
12h 05m1 stop Newark
United Airlines Logo
6:00 am - 2:16 pmSTI  Santiago de los Caballeros-TPA Tampa
9h 16m1 stop Newark
$460United Airlines
Wed, Nov 4 - Wed, Nov 11
JetBlue Logo
7:45 am - 3:23 pmTPA  Tampa-STI Santiago de los Caballeros
6h 38m1 stop Fort Lauderdale
JetBlue Logo
5:01 am - 11:20 amSTI  Santiago de los Caballeros-TPA Tampa
7h 19m1 stop Fort Lauderdale
$465JetBlue
Fri, Nov 13 - Thu, Nov 19

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American Airlines flights from Tampa to Santiago de los Caballeros

Our best American Airlines deals on Tampa to Santiago de los Caballeros flight tickets
American Airlines
Nov 13
TPA7:00 amTampa
8h 08m
1 stop
STI4:08 pmSantiago de los Caballeros
Nov 19
STI5:36 pmSantiago de los Caballeros
17h 17m
1 stop
TPA9:53 amTampa
$382
American Airlines
Oct 13
TPA10:10 amTampa
4h 02m
1 stop
STI2:12 pmSantiago de los Caballeros
Oct 21
STI3:12 pmSantiago de los Caballeros
18h 34m
2 stops
TPA9:46 amTampa
$387
American Airlines
Nov 5
TPA8:30 pmTampa
18h 38m
1 stop
STI4:08 pmSantiago de los Caballeros
Nov 12
STI4:16 pmSantiago de los Caballeros
18h 37m
1 stop
TPA9:53 amTampa
$389

Frontier flights from Tampa to Santiago de los Caballeros

Our best Frontier deals on Tampa to Santiago de los Caballeros flight tickets
Frontier
Oct 16
TPA4:45 pmTampa
17h 43m
1 stop
STI10:28 amSantiago de los Caballeros
Oct 24
STI11:43 amSantiago de los Caballeros
21h 06m
1 stop
TPA8:49 amTampa
$415
Frontier
Oct 16
TPA4:45 pmTampa
17h 43m
1 stop
STI10:28 amSantiago de los Caballeros
Oct 24
STI11:43 amSantiago de los Caballeros
11h 11m
2 stops
TPA10:54 pmTampa
$482

momondo Fare Finder

 
Use the filters below to find and compare flights from Tampa to Santiago de los Caballeros that are best for you.

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Cheapest round-trip

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Fri 11/13

7:00 am-4:08 pm

1 stop8h 08m

Santiago de los Caballeros

Thu 11/19

5:36 pm-9:53 am

1 stop17h 17m

$382

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Tue 10/13

10:10 am-2:12 pm

1 stop4h 02m

Santiago de los Caballeros

Wed 10/21

3:12 pm-9:46 am

2 stops18h 34m

$387

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Tue 10/13

6:00 am-2:12 pm

2 stops8h 12m

Santiago de los Caballeros

Wed 10/21

3:12 pm-12:35 am

2 stops9h 23m

$387

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Tue 11/24

7:06 am-4:36 pm

1 stop8h 30m

Santiago de los Caballeros

Tue 12/1

5:08 pm-11:39 am

2 stops19h 31m

$387

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Fri 10/16

4:45 pm-10:28 am

1 stop17h 43m

Santiago de los Caballeros

Sat 10/24

11:43 am-8:49 am

1 stop21h 06m

$415

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Fri 11/13

7:45 am-3:23 pm

1 stop6h 38m

Santiago de los Caballeros

Thu 11/19

5:01 am-11:20 am

1 stop7h 19m

$435
Quickest round-trip

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Wed 11/4

7:45 am-3:23 pm

1 stop6h 38m

Santiago de los Caballeros

Mon 11/9

9:12 am-2:03 pm

1 stop5h 51m

$435

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Wed 11/4

4:51 am-2:54 pm

1 stop9h 03m

Santiago de los Caballeros

Mon 11/9

4:01 pm-12:40 pm

1 stop21h 39m

$455

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Wed 11/4

10:46 am-11:51 pm

1 stop12h 05m

Santiago de los Caballeros

Wed 11/11

6:00 am-2:16 pm

1 stop9h 16m

$460

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Fri 11/13

7:45 am-3:23 pm

1 stop6h 38m

Santiago de los Caballeros

Thu 11/19

5:01 am-11:20 am

1 stop7h 19m

$465

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Tampa to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Tampa and Santiago de los Caballeros?

Prices are currently low for flights on this route.

Typical prices usually range from $407 to $461.
The lowest price recently found on this route was $382.

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Tampa is in January. Flight prices, which tend to average around $349, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of January, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $382.

How far in advance should I book a flight from Tampa to Santiago de los Caballeros?

You are more likely to see cheaper flights to Santiago de los Caballeros from Tampa when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago de los Caballeros for around $499 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago de los Caballeros from Tampa for as low as $338 on momondo.

How have Tampa to Santiago de los Caballeros flight prices changed over time?

As of September 2026, prices for Tampa to Santiago de los Caballeros flights are approximately 137% more expensive when compared to flights at the same time last year.

When to book flights from Tampa to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Santiago de los Caballeros (TPA to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Santiago de los Caballeros

Best Price Found

$174

Fastest flight time

6h 20m

Direct flights

None
The best one-way flight to Santiago de los Caballeros from Tampa in the past 72 hours is $174. The best round-trip flight deal from Tampa to Santiago de los Caballeros found on momondo in the last 72 hours is $382.
The fastest flight from Tampa to Santiago de los Caballeros takes 6h 20m
There are no direct flights from Tampa to Santiago de los Caballeros. There are no popular flight routes from Tampa to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from Tampa to Santiago de los Caballeros

  • How far is Tampa to Santiago de los Caballeros by plane?

    Santiago de los Caballeros is 946.3 mi away from Tampa. A reasonable flight in good conditions will take 6h 20m.

  • When did momondo last update prices for flights from Tampa Airport to Santiago de los Caballeros Airport?

    Prices for flights from Tampa Airport to Santiago de los Caballeros Airport refresh daily.

  • How many operators does momondo search for flights from Tampa Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Tampa Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents required for your trip to Santiago de los Caballeros Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago de los Caballeros Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Tampa to Santiago de los Caballeros?

Best airlines flying from Tampa to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Tampa to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $358Free CancellationRating
7.0
12,079 reviews
Search American Airlines flights
JetBluePriceFrom $436Free CancellationRating
7.1
3,037 reviews
Search JetBlue flights

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Tampa.

Can I find flights from Tampa to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago de los Caballeros from Tampa with this policy.

How can momondo help me find flights from Tampa to Santiago de los Caballeros?

momondo provides multiple filters to help you find the best flight to Santiago de los Caballeros from Tampa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Tampa to Santiago de los Caballeros right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago de los Caballeros, momondo offers a useful price alert feature which will track prices for flights to Santiago de los Caballeros from Tampa and alert you when they change.

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