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Cheap flights from Tampa to Santiago de los Caballeros from $147

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Santiago de los Caballeros departing on 10/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Tampa to Santiago de los Caballeros

Cheap round-trip flights

Spirit Airlines Logo
10:59 pm - 10:38 amTPA-STI
11h 39m1 stop
Spirit Airlines Logo
11:43 am - 5:19 pmSTI-TPA
5h 36m1 stop
$299Spirit Airlines
Find Deal
Fri, Oct 17 - Mon, Oct 27
Spirit Airlines Logo
6:28 am - 10:38 amTPA-STI
4h 10m1 stop
Spirit Airlines Logo
11:43 am - 11:26 pmSTI-TPA
11h 43m1 stop
$301Spirit Airlines
Find Deal
Tue, Oct 7 - Tue, Oct 28
Logo
11:30 am - 11:03 amTPA-STI
23h 33m2 stops
Logo
12:10 pm - 11:51 pmSTI-TPA
11h 41m1 stop
$382
Find Deal
Sat, Sep 27 - Wed, Oct 1
Logo
10:59 pm - 10:38 amTPA-STI
11h 39m1 stop
Logo
11:43 am - 11:42 pmSTI-TPA
11h 59m2 stops
$383
Find Deal
Wed, Oct 22 - Mon, Oct 27
JetBlue Logo
6:00 am - 4:15 pmTPA-STI
9h 15m1 stop
JetBlue Logo
4:41 am - 9:53 pmSTI-TPA
18h 12m1 stop
$407JetBlue
Find Deal
Mon, Nov 3 - Sun, Nov 16
JetBlue Logo
2:00 pm - 2:21 amTPA-STI
12h 21m1 stop
JetBlue Logo
3:43 am - 5:53 pmSTI-TPA
14h 10m1 stop
$421JetBlue
Find Deal
Tue, Oct 7 - Mon, Oct 27
Delta Logo
7:35 am - 7:11 pmTPA-STI
11h 36m1 stop
Delta Logo
6:11 am - 6:00 pmSTI-TPA
11h 49m1 stop
$437Delta
Find Deal
Fri, Sep 26 - Sun, Oct 5
Delta Logo
8:30 am - 7:36 pmTPA-STI
10h 06m1 stop
Delta Logo
2:31 pm - 10:30 pmSTI-TPA
8h 59m1 stop
$439Delta
Find Deal
Sat, Nov 15 - Mon, Nov 24
American Airlines Logo
6:35 pm - 12:27 pmTPA-STI
17h 52m2 stops
American Airlines Logo
1:29 pm - 9:20 amSTI-TPA
19h 51m2 stops
$453American Airlines
Find Deal
Fri, Sep 26 - Sun, Oct 5
American Airlines Logo
4:25 pm - 12:27 pmTPA-STI
20h 02m2 stops
American Airlines Logo
1:29 pm - 9:20 amSTI-TPA
19h 51m2 stops
$458American Airlines
Find Deal
Fri, Sep 26 - Sun, Oct 5

Spirit Airlines flights from Tampa to Santiago de los Caballeros

Our best Spirit Airlines deals on Tampa to Santiago de los Caballeros flight tickets
Spirit Airlines
Oct 17
TPA10:59 pmTampa
11h 39m
1 stop
STI10:38 amSantiago de los Caballeros
Oct 27
STI11:43 amSantiago de los Caballeros
5h 36m
1 stop
TPA5:19 pmTampa
$299
Find similar
Spirit Airlines
Oct 7
TPA6:28 amTampa
4h 10m
1 stop
STI10:38 amSantiago de los Caballeros
Oct 28
STI11:43 amSantiago de los Caballeros
11h 43m
1 stop
TPA11:26 pmTampa
$301
Find similar
Spirit Airlines
Sep 28
TPA7:18 pmTampa
15h 45m
1 stop
STI11:03 amSantiago de los Caballeros
Oct 4
STI12:10 pmSantiago de los Caballeros
10h 58m
1 stop
TPA11:08 pmTampa
$312
Find similar

Delta flights from Tampa to Santiago de los Caballeros

Our best Delta deals on Tampa to Santiago de los Caballeros flight tickets
Delta
Sep 26
TPA7:35 amTampa
11h 36m
1 stop
STI7:11 pmSantiago de los Caballeros
Oct 5
STI6:11 amSantiago de los Caballeros
11h 49m
1 stop
TPA6:00 pmTampa
$437
Find similar
Delta
Nov 15
TPA8:30 amTampa
10h 06m
1 stop
STI7:36 pmSantiago de los Caballeros
Nov 24
STI2:31 pmSantiago de los Caballeros
8h 59m
1 stop
TPA10:30 pmTampa
$439
Find similar
Delta
Sep 17
TPA6:00 amTampa
13h 11m
2 stops
STI7:11 pmSantiago de los Caballeros
Sep 27
STI6:11 amSantiago de los Caballeros
17h 44m
2 stops
TPA11:55 pmTampa
$441
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 27, 2025.
Use the filters below to find and compare flights from Tampa to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Fri 10/17

10:59 pm-10:38 am

1 stop11h 39m

Santiago de los Caballeros

Mon 10/27

11:43 am-5:19 pm

1 stop5h 36m

$299

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Tue 10/7

6:28 am-10:38 am

1 stop4h 10m

Santiago de los Caballeros

Tue 10/28

11:43 am-11:26 pm

1 stop11h 43m

$301

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sat 9/27

11:30 am-11:03 am

2 stops23h 33m

Santiago de los Caballeros

Wed 10/1

12:10 pm-11:51 pm

1 stop11h 41m

$382

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Wed 10/22

10:59 pm-10:38 am

1 stop11h 39m

Santiago de los Caballeros

Mon 10/27

11:43 am-11:42 pm

2 stops11h 59m

$383

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Mon 11/3

6:00 am-4:15 pm

1 stop9h 15m

Santiago de los Caballeros

Sun 11/16

4:41 am-9:53 pm

1 stop18h 12m

$407

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Tue 10/7

2:00 pm-2:21 am

1 stop12h 21m

Santiago de los Caballeros

Mon 10/27

3:43 am-5:53 pm

1 stop14h 10m

$421

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Fri 9/26

7:35 am-7:11 pm

1 stop11h 36m

Santiago de los Caballeros

Sun 10/5

6:11 am-6:00 pm

1 stop11h 49m

$437

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sat 11/15

8:30 am-7:36 pm

1 stop10h 06m

Santiago de los Caballeros

Mon 11/24

2:31 pm-10:30 pm

1 stop8h 59m

$439

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Fri 9/26

6:35 pm-12:27 pm

2 stops17h 52m

Santiago de los Caballeros

Sun 10/5

1:29 pm-9:20 am

2 stops19h 51m

$453

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Fri 9/26

4:25 pm-12:27 pm

2 stops20h 02m

Santiago de los Caballeros

Sun 10/5

1:29 pm-9:20 am

2 stops19h 51m

$458

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Tampa to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Tampa is in September. Flight prices, which tend to average around $443, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of September, then flying in July is also cheap. Prices for this month can be found on momondo for an average of $460.

What is the cheapest day to depart on your flight to Santiago de los Caballeros?

The cheapest day to depart from Tampa to Santiago de los Caballeros is on a Thursday when prices can be found for as low as $423. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Tampa to Santiago de los Caballeros for around $509.

What is the cheapest time of day to depart on your flight to Santiago de los Caballeros?

Our data shows that the cheapest Tampa to Santiago de los Caballeros flights are usually those with departure times in the evening. Our users have found flights to Santiago de los Caballeros in the evening for as low as $289. In the afternoon is when there is more demand to fly to Santiago de los Caballeros, so prices are often more expensive at around $718 per ticket.

How far in advance should I book a flight to Santiago de los Caballeros?

You are more likely to see cheaper flights to Santiago de los Caballeros from Tampa when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago de los Caballeros for around $555 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago de los Caballeros from Tampa for as low as $366 on momondo.

How have Tampa to Santiago de los Caballeros flight prices changed over time?

As of August 2025, prices for Tampa to Santiago de los Caballeros flights are approximately 55% more expensive when compared to flights at the same time last year.

When to book flights from Tampa to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Santiago de los Caballeros (TPA to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Santiago de los Caballeros

Direct flights

None
There are no direct flights from Tampa to Santiago de los Caballeros. There are no popular flight routes from Tampa to Santiago de los Caballeros.
Search flight deals

  • How far is Tampa to Santiago de los Caballeros by plane?

    Santiago de los Caballeros is 946.3 mi away from Tampa. A reasonable flight in good conditions will take 4h 10m.

  • When did momondo last update prices for flights from Tampa Airport to Santiago de los Caballeros Airport?

    Prices for flights from Tampa Airport to Santiago de los Caballeros Airport refresh daily.

  • How many operators does momondo search for flights from Tampa Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Tampa Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents required for your trip to Santiago de los Caballeros Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago de los Caballeros Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Tampa to Santiago de los Caballeros?

Best airlines flying from Tampa to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Tampa to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $330Free CancellationRating
6.3
8,030 reviews
Search Spirit Airlines flights
American AirlinesPriceFrom $436Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
United AirlinesPriceFrom $483Free CancellationRating
7.4
8,945 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Tampa.

Can I find flights from Tampa to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago de los Caballeros from Tampa with this policy.

How can momondo help me find flights from Tampa to Santiago de los Caballeros?

momondo provides multiple filters to help you find the best flight to Santiago de los Caballeros from Tampa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Tampa to Santiago de los Caballeros right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago de los Caballeros, momondo offers a useful price alert feature which will track prices for flights to Santiago de los Caballeros from Tampa and alert you when they change.

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