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Cheap flights from Tampa to Santiago de los Caballeros from $221

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Tampa to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:00 am - 9:29 pmTPA  Tampa-STI Santiago de los Caballeros
13h 29m1 stop Miami
American Airlines Logo
7:18 am - 7:21 pmSTI  Santiago de los Caballeros-TPA Tampa
13h 03m1 stop Miami
$412American Airlines
Thu, Jan 14 - Tue, Jan 19
Delta Logo
8:30 am - 12:53 amTPA  Tampa-STI Santiago de los Caballeros
15h 23m1 stop New York John F Kennedy Intl
Delta Logo
6:38 am - 11:04 pmSTI  Santiago de los Caballeros-TPA Tampa
17h 26m1 stop New York John F Kennedy Intl
$412Delta
Mon, Feb 1 - Thu, Feb 4
American Airlines Logo
6:34 pm - 1:22 pmTPA  Tampa-STI Santiago de los Caballeros
17h 48m2 stops Charlotte Douglas Miami
American Airlines Logo
7:18 am - 9:44 pmSTI  Santiago de los Caballeros-TPA Tampa
15h 26m2 stops Miami Charlotte Douglas
$417American Airlines
Mon, Feb 1 - Thu, Feb 4
American Airlines Logo
6:34 pm - 1:22 pmTPA  Tampa-STI Santiago de los Caballeros
17h 48m2 stops Charlotte Douglas Miami
American Airlines Logo
7:18 am - 5:43 pmSTI  Santiago de los Caballeros-TPA Tampa
11h 25m1 stop Miami
$417American Airlines
Mon, Feb 1 - Thu, Feb 4
American Airlines Logo
6:41 pm - 12:36 pmTPA  Tampa-STI Santiago de los Caballeros
17h 55m2 stops Charlotte Douglas Miami
American Airlines Logo
6:10 am - 12:56 pmSTI  Santiago de los Caballeros-TPA Tampa
6h 46m1 stop Miami
$417American Airlines
Mon, Mar 22 - Wed, Mar 31
Delta Logo
8:30 am - 12:53 amTPA  Tampa-STI Santiago de los Caballeros
15h 23m1 stop New York John F Kennedy Intl
Delta Logo
6:38 am - 11:04 pmSTI  Santiago de los Caballeros-TPA Tampa
17h 26m1 stop New York John F Kennedy Intl
$432Delta
Mon, Feb 1 - Thu, Feb 4
Delta Logo
8:30 am - 12:53 amTPA  Tampa-STI Santiago de los Caballeros
15h 23m1 stop New York John F Kennedy Intl
Delta Logo
6:38 am - 9:15 pmSTI  Santiago de los Caballeros-TPA Tampa
15h 37m2 stops New York John F Kennedy Intl Detroit Metropolitan Wayne County
$437Delta
Mon, Feb 1 - Thu, Feb 4
JetBlue Logo
9:00 am - 6:45 pmTPA  Tampa-STI Santiago de los Caballeros
8h 45m1 stop San Juan Luis Munoz Marin Intl
JetBlue Logo
5:01 am - 11:20 amSTI  Santiago de los Caballeros-TPA Tampa
7h 19m1 stop Fort Lauderdale
$658JetBlue
Sun, Nov 22 - Sun, Nov 29
JetBlue Logo
9:00 am - 6:45 pmTPA  Tampa-STI Santiago de los Caballeros
8h 45m1 stop San Juan Luis Munoz Marin Intl
JetBlue Logo
5:01 am - 11:20 amSTI  Santiago de los Caballeros-TPA Tampa
7h 19m1 stop Fort Lauderdale
$689JetBlue
Sun, Nov 22 - Sun, Nov 29
JetBlue Logo
9:00 am - 6:45 pmTPA  Tampa-STI Santiago de los Caballeros
8h 45m1 stop San Juan Luis Munoz Marin Intl
JetBlue Logo
5:01 am - 11:20 amSTI  Santiago de los Caballeros-TPA Tampa
7h 19m1 stop Fort Lauderdale
$700JetBlue
Sun, Nov 22 - Sun, Nov 29

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American Airlines flights from Tampa to Santiago de los Caballeros

Our best American Airlines deals on Tampa to Santiago de los Caballeros flight tickets
American Airlines
Jan 14
TPA7:00 amTampa
13h 29m
1 stop
STI9:29 pmSantiago de los Caballeros
Jan 19
STI7:18 amSantiago de los Caballeros
13h 03m
1 stop
TPA7:21 pmTampa
$412
American Airlines
Feb 1
TPA6:34 pmTampa
17h 48m
2 stops
STI1:22 pmSantiago de los Caballeros
Feb 4
STI7:18 amSantiago de los Caballeros
15h 26m
2 stops
TPA9:44 pmTampa
$417
American Airlines
Mar 22
TPA7:36 pmTampa
24h 20m
1 stop
STI7:56 pmSantiago de los Caballeros
Mar 31
STI6:10 amSantiago de los Caballeros
6h 46m
1 stop
TPA12:56 pmTampa
$419

Delta flights from Tampa to Santiago de los Caballeros

Our best Delta deals on Tampa to Santiago de los Caballeros flight tickets
Delta
Nov 10
TPA11:57 amTampa
12h 02m
1 stop
STI12:59 amSantiago de los Caballeros
Nov 13
STI7:00 amSantiago de los Caballeros
12h 41m
1 stop
TPA6:41 pmTampa
$476
Delta
Nov 10
TPA6:20 amTampa
17h 39m
2 stops
STI12:59 amSantiago de los Caballeros
Nov 13
STI9:25 pmSantiago de los Caballeros
16h 50m
2 stops
TPA1:15 pmTampa
$481
Delta
Nov 10
TPA11:57 amTampa
12h 02m
1 stop
STI12:59 amSantiago de los Caballeros
Nov 13
STI7:00 amSantiago de los Caballeros
16h 59m
1 stop
TPA10:59 pmTampa
$496

momondo Fare Finder

 
Use the filters below to find and compare flights from Tampa to Santiago de los Caballeros that are best for you.

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Price

Cheapest round-trip

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Thu 1/14

7:00 am-9:29 pm

1 stop13h 29m

Santiago de los Caballeros

Tue 1/19

7:18 am-7:21 pm

1 stop13h 03m

$412

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Mon 2/1

8:30 am-12:53 am

1 stop15h 23m

Santiago de los Caballeros

Thu 2/4

6:38 am-11:04 pm

1 stop17h 26m

$412

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Mon 2/1

6:34 pm-1:22 pm

2 stops17h 48m

Santiago de los Caballeros

Thu 2/4

7:18 am-9:44 pm

2 stops15h 26m

$417

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Mon 2/1

6:34 pm-1:22 pm

2 stops17h 48m

Santiago de los Caballeros

Thu 2/4

7:18 am-5:43 pm

1 stop11h 25m

$417

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Mon 3/22

6:41 pm-12:36 pm

2 stops17h 55m

Santiago de los Caballeros

Wed 3/31

6:10 am-12:56 pm

1 stop6h 46m

$417

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Mon 2/1

8:30 am-12:53 am

1 stop15h 23m

Santiago de los Caballeros

Thu 2/4

6:38 am-11:04 pm

1 stop17h 26m

$432

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Mon 2/1

8:30 am-12:53 am

1 stop15h 23m

Santiago de los Caballeros

Thu 2/4

6:38 am-9:15 pm

2 stops15h 37m

$437
Quickest round-trip

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Sun 11/22

9:00 am-6:45 pm

1 stop8h 45m

Santiago de los Caballeros

Sun 11/29

5:01 am-11:20 am

1 stop7h 19m

$658

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Sun 11/22

9:00 am-6:45 pm

1 stop8h 45m

Santiago de los Caballeros

Sun 11/29

5:01 am-11:20 am

1 stop7h 19m

$689

TampaSantiago de los Caballeros

TPA Tampa - STI Santiago de los Caballeros

TPASTI

Tampa

Sun 11/22

9:00 am-6:45 pm

1 stop8h 45m

Santiago de los Caballeros

Sun 11/29

5:01 am-11:20 am

1 stop7h 19m

$700

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Tampa to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Tampa and Santiago de los Caballeros?

Prices are currently low for flights on this route.

Typical prices usually range from $441 to $478.
The lowest price recently found on this route was $412.

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Tampa is in January. Flight prices, which tend to average around $358, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of January, then flying in February is also cheap. Prices for this month can be found on momondo for an average of $382.

How far in advance should I book a flight from Tampa to Santiago de los Caballeros?

You are more likely to see cheaper flights to Santiago de los Caballeros from Tampa when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago de los Caballeros for around $502 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago de los Caballeros from Tampa for as low as $338 on momondo.

How have Tampa to Santiago de los Caballeros flight prices changed over time?

As of November 2026, prices for Tampa to Santiago de los Caballeros flights are approximately 23% cheaper when compared to flights at the same time last year.

When to book flights from Tampa to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Santiago de los Caballeros (TPA to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Santiago de los Caballeros

Best Price Found

$221

Fastest flight time

7h 09m

Direct flights

None
The best one-way flight to Santiago de los Caballeros from Tampa in the past 72 hours is $221. The best round-trip flight deal from Tampa to Santiago de los Caballeros found on momondo in the last 72 hours is $412.
The fastest flight from Tampa to Santiago de los Caballeros takes 7h 09m
There are no direct flights from Tampa to Santiago de los Caballeros. There are no popular flight routes from Tampa to Santiago de los Caballeros.
Search flight deals

Frequently asked questions about flying from Tampa to Santiago de los Caballeros

  • How far is Tampa to Santiago de los Caballeros by plane?

    Santiago de los Caballeros is 946.3 mi away from Tampa. A reasonable flight in good conditions will take 7h 09m.

  • When did momondo last update prices for flights from Tampa Airport to Santiago de los Caballeros Airport?

    Prices for flights from Tampa Airport to Santiago de los Caballeros Airport refresh daily.

  • How many operators does momondo search for flights from Tampa Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Tampa Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents required for your trip to Santiago de los Caballeros Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago de los Caballeros Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Tampa to Santiago de los Caballeros?

Best airlines flying from Tampa to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Tampa to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $358Free CancellationRating
7.0
12,233 reviews
Search American Airlines flights
JetBluePriceFrom $436Free CancellationRating
7.1
3,064 reviews
Search JetBlue flights

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Tampa.

Can I find flights from Tampa to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago de los Caballeros from Tampa with this policy.

How can momondo help me find flights from Tampa to Santiago de los Caballeros?

momondo provides multiple filters to help you find the best flight to Santiago de los Caballeros from Tampa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Tampa to Santiago de los Caballeros right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago de los Caballeros, momondo offers a useful price alert feature which will track prices for flights to Santiago de los Caballeros from Tampa and alert you when they change.

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