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Cheap flights from Tampa to Santiago de los Caballeros from $108

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Santiago de los Caballeros departing on 1/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Tampa to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
8:38 am - 3:33 pm
TPA
-
STI
5h 55m1 stop
Spirit Airlines Logo
4:40 pm - 8:49 pm
STI
-
TPA
5h 09m1 stop
$240Spirit Airlines
Mon, Jan 12 - Thu, Jan 22
Spirit Airlines Logo
8:27 am - 3:35 pm
TPA
-
STI
6h 08m1 stop
Spirit Airlines Logo
4:40 pm - 8:44 pm
STI
-
TPA
5h 04m1 stop
$246Spirit Airlines
Sat, Feb 21 - Wed, Feb 25
Spirit Airlines Logo
8:27 am - 3:35 pm
TPA
-
STI
6h 08m1 stop
Spirit Airlines Logo
4:40 pm - 8:44 pm
STI
-
TPA
5h 04m1 stop
$257Spirit Airlines
Sat, Feb 21 - Wed, Feb 25
Spirit Airlines Logo
9:03 pm - 2:42 am
TPA
-
STI
4h 39m1 stop
Spirit Airlines Logo
4:40 pm - 8:49 pm
STI
-
TPA
5h 09m1 stop
$260Spirit Airlines
Tue, Jan 6 - Thu, Jan 29
Spirit Airlines Logo
8:38 am - 3:33 pm
TPA
-
STI
5h 55m1 stop
Spirit Airlines Logo
4:40 pm - 8:49 pm
STI
-
TPA
5h 09m1 stop
$262Spirit Airlines
Mon, Jan 12 - Thu, Jan 22
Spirit Airlines Logo
6:55 pm - 3:33 pm
TPA
-
STI
19h 38m1 stop
Spirit Airlines Logo
4:40 pm - 8:49 pm
STI
-
TPA
5h 09m1 stop
$268Spirit Airlines
Sat, Jan 10 - Wed, Jan 14
Spirit Airlines Logo
10:05 am - 3:33 pm
TPA
-
STI
4h 28m1 stop
Spirit Airlines Logo
4:40 pm - 8:49 pm
STI
-
TPA
5h 09m1 stop
$269Spirit Airlines
Wed, Jan 14 - Fri, Jan 30
Spirit Airlines Logo
6:03 pm - 2:42 am
TPA
-
STI
7h 39m1 stop
Spirit Airlines Logo
4:40 pm - 8:49 pm
STI
-
TPA
5h 09m1 stop
$270Spirit Airlines
Tue, Jan 6 - Thu, Jan 29
Spirit Airlines Logo
8:38 am - 3:33 pm
TPA
-
STI
5h 55m1 stop
Spirit Airlines Logo
4:40 pm - 8:49 pm
STI
-
TPA
5h 09m1 stop
$273Spirit Airlines
Sun, Jan 25 - Mon, Feb 2
Spirit Airlines Logo
8:27 am - 3:35 pm
TPA
-
STI
6h 08m1 stop
Spirit Airlines Logo
4:40 pm - 8:44 pm
STI
-
TPA
5h 04m1 stop
$274Spirit Airlines
Fri, Feb 20 - Mon, Feb 23

American Airlines flights from Tampa to Santiago de los Caballeros

Our best American Airlines deals on Tampa to Santiago de los Caballeros flight tickets
American Airlines
Jan 30
TPA8:48 amTampa
5h 44m
1 stop
STI3:32 pmSantiago de los Caballeros
Feb 6
STI6:00 amSantiago de los Caballeros
11h 00m
2 stops
TPA4:00 pmTampa
$291
Find similar
American Airlines
Dec 31
TPA6:00 amTampa
14h 04m
1 stop
STI9:04 pmSantiago de los Caballeros
Jan 14
STI6:00 amSantiago de los Caballeros
12h 52m
1 stop
TPA5:52 pmTampa
$300
Find similar
American Airlines
Jan 12
TPA6:00 amTampa
14h 46m
2 stops
STI9:46 pmSantiago de los Caballeros
Jan 22
STI6:00 amSantiago de los Caballeros
11h 00m
2 stops
TPA4:00 pmTampa
$304
Find similar

Delta flights from Tampa to Santiago de los Caballeros

Our best Delta deals on Tampa to Santiago de los Caballeros flight tickets
Delta
Jan 24
TPA12:00 pmTampa
7h 34m
1 stop
STI8:34 pmSantiago de los Caballeros
Jan 31
STI9:59 pmSantiago de los Caballeros
13h 19m
1 stop
TPA10:18 amTampa
$300
Find similar
Delta
Jan 24
TPA12:32 pmTampa
11h 18m
2 stops
STI12:50 amSantiago de los Caballeros
Jan 31
STI6:38 amSantiago de los Caballeros
12h 57m
2 stops
TPA6:35 pmTampa
$333
Find similar
Delta
Jan 14
TPA8:30 amTampa
15h 20m
2 stops
STI12:50 amSantiago de los Caballeros
Jan 30
STI9:59 pmSantiago de los Caballeros
16h 47m
2 stops
TPA1:46 pmTampa
$346
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Tampa to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Mon 1/12

8:38 am-3:33 pm

1 stop5h 55m

Santiago de los Caballeros

Thu 1/22

4:40 pm-8:49 pm

1 stop5h 09m

$240

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sat 2/21

8:27 am-3:35 pm

1 stop6h 08m

Santiago de los Caballeros

Wed 2/25

4:40 pm-8:44 pm

1 stop5h 04m

$246

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sat 2/21

8:27 am-3:35 pm

1 stop6h 08m

Santiago de los Caballeros

Wed 2/25

4:40 pm-8:44 pm

1 stop5h 04m

$257

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Tue 1/6

9:03 pm-2:42 am

1 stop4h 39m

Santiago de los Caballeros

Thu 1/29

4:40 pm-8:49 pm

1 stop5h 09m

$260

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Mon 1/12

8:38 am-3:33 pm

1 stop5h 55m

Santiago de los Caballeros

Thu 1/22

4:40 pm-8:49 pm

1 stop5h 09m

$262

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sat 1/10

6:55 pm-3:33 pm

1 stop19h 38m

Santiago de los Caballeros

Wed 1/14

4:40 pm-8:49 pm

1 stop5h 09m

$268

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Wed 1/14

10:05 am-3:33 pm

1 stop4h 28m

Santiago de los Caballeros

Fri 1/30

4:40 pm-8:49 pm

1 stop5h 09m

$269

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Tue 1/6

6:03 pm-2:42 am

1 stop7h 39m

Santiago de los Caballeros

Thu 1/29

4:40 pm-8:49 pm

1 stop5h 09m

$270

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sun 1/25

8:38 am-3:33 pm

1 stop5h 55m

Santiago de los Caballeros

Mon 2/2

4:40 pm-8:49 pm

1 stop5h 09m

$273

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Fri 2/20

8:27 am-3:35 pm

1 stop6h 08m

Santiago de los Caballeros

Mon 2/23

4:40 pm-8:44 pm

1 stop5h 04m

$274

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Tampa to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Tampa is in October. Flight prices, which tend to average around $370, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of October, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $436.

What is the cheapest day to depart on your flight to Santiago de los Caballeros?

The cheapest day to depart from Tampa to Santiago de los Caballeros is on a Thursday when prices can be found for as low as $423. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Tampa to Santiago de los Caballeros for around $509.

What is the cheapest time of day to depart on your flight to Santiago de los Caballeros?

Our data shows that the cheapest Tampa to Santiago de los Caballeros flights are usually those with departure times in the evening. Our users have found flights to Santiago de los Caballeros in the evening for as low as $289. In the afternoon is when there is more demand to fly to Santiago de los Caballeros, so prices are often more expensive at around $718 per ticket.

How have Tampa to Santiago de los Caballeros flight prices changed over time?

As of December 2025, prices for Tampa to Santiago de los Caballeros flights are approximately 4% more expensive when compared to flights at the same time last year.

When to book flights from Tampa to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Santiago de los Caballeros (TPA to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Santiago de los Caballeros

Fastest flight time

4h 39m

Direct flights

None
The fastest flight from Tampa to Santiago de los Caballeros takes 4h 39m
There are no direct flights from Tampa to Santiago de los Caballeros. There are no popular flight routes from Tampa to Santiago de los Caballeros.
Search flight deals

  • How far is Tampa to Santiago de los Caballeros by plane?

    Santiago de los Caballeros is 946.3 mi away from Tampa. A reasonable flight in good conditions will take 4h 39m.

  • When did momondo last update prices for flights from Tampa Airport to Santiago de los Caballeros Airport?

    Prices for flights from Tampa Airport to Santiago de los Caballeros Airport refresh daily.

  • How many operators does momondo search for flights from Tampa Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Tampa Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents required for your trip to Santiago de los Caballeros Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago de los Caballeros Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Tampa to Santiago de los Caballeros?

Best airlines flying from Tampa to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Tampa to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $290Free CancellationRating
6.3
8,190 reviews
Search Spirit Airlines flights
DeltaPriceFrom $315Free CancellationRating
7.9
8,005 reviews
Search Delta flights
American AirlinesPriceFrom $370Free CancellationRating
7.2
11,055 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Tampa.

Can I find flights from Tampa to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago de los Caballeros from Tampa with this policy.

How can momondo help me find flights from Tampa to Santiago de los Caballeros?

momondo provides multiple filters to help you find the best flight to Santiago de los Caballeros from Tampa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Tampa to Santiago de los Caballeros right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago de los Caballeros, momondo offers a useful price alert feature which will track prices for flights to Santiago de los Caballeros from Tampa and alert you when they change.

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