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Cheap flights from Tampa to Santiago de los Caballeros from $123

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Tampa to Santiago de los Caballeros departing on 11/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Tampa to Santiago de los Caballeros

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
9:37 pm - 12:22 pmTPA-STI
13h 45m1 stop
Spirit Airlines Logo
1:17 pm - 10:51 pmSTI-TPA
10h 34m1 stop
$269Spirit Airlines
Find Deal
Sat, Nov 15 - Tue, Nov 18
Spirit Airlines Logo
8:11 pm - 2:42 amTPA-STI
5h 31m1 stop
Spirit Airlines Logo
6:18 pm - 10:18 pmSTI-TPA
5h 00m1 stop
$277Spirit Airlines
Find Deal
Wed, Dec 10 - Wed, Jan 28
Spirit Airlines Logo
9:37 pm - 12:22 pmTPA-STI
13h 45m1 stop
Spirit Airlines Logo
1:17 pm - 10:51 pmSTI-TPA
10h 34m1 stop
$280Spirit Airlines
Find Deal
Sat, Nov 15 - Mon, Nov 17
Spirit Airlines Logo
6:45 am - 12:22 pmTPA-STI
4h 37m1 stop
Spirit Airlines Logo
1:17 pm - 10:51 pmSTI-TPA
10h 34m1 stop
$297Spirit Airlines
Find Deal
Fri, Nov 14 - Sun, Nov 16
American Airlines Logo
6:00 am - 9:46 pmTPA-STI
14h 46m1 stop
American Airlines Logo
6:00 am - 5:52 pmSTI-TPA
12h 52m1 stop
$300American Airlines
Find Deal
Thu, Jan 15 - Tue, Jan 20
American Airlines Logo
10:42 am - 9:46 pmTPA-STI
10h 04m1 stop
American Airlines Logo
6:00 am - 9:09 pmSTI-TPA
16h 09m2 stops
$304American Airlines
Find Deal
Thu, Jan 15 - Tue, Jan 20
Multiple Airlines Logo
8:09 am - 2:42 amTPA-STI
17h 33m1 stop
Multiple Airlines Logo
3:43 am - 11:29 pmSTI-TPA
20h 46m2 stops
$351Multiple Airlines
Find Deal
Fri, Dec 5 - Tue, Dec 16
Delta Logo
7:15 pm - 1:06 pmTPA-STI
16h 51m2 stops
Delta Logo
6:40 am - 4:59 pmSTI-TPA
11h 19m2 stops
$362Delta
Find Deal
Sat, Nov 15 - Tue, Nov 18
Delta Logo
1:45 pm - 12:59 amTPA-STI
10h 14m2 stops
Delta Logo
9:01 pm - 12:37 pmSTI-TPA
16h 36m2 stops
$380Delta
Find Deal
Sat, Nov 15 - Mon, Nov 17
JetBlue Logo
6:00 am - 3:45 pmTPA-STI
8h 45m1 stop
JetBlue Logo
4:10 am - 6:40 pmSTI-TPA
15h 30m1 stop
$422JetBlue
Find Deal
Sat, Jan 24 - Sun, Feb 1

Spirit Airlines flights from Tampa to Santiago de los Caballeros

Our best Spirit Airlines deals on Tampa to Santiago de los Caballeros flight tickets
Spirit Airlines
Nov 15
TPA9:37 pmTampa
13h 45m
1 stop
STI12:22 pmSantiago de los Caballeros
Nov 18
STI1:17 pmSantiago de los Caballeros
10h 34m
1 stop
TPA10:51 pmTampa
$269
Find similar
Spirit Airlines
Dec 10
TPA8:11 pmTampa
5h 31m
1 stop
STI2:42 amSantiago de los Caballeros
Jan 28
STI6:18 pmSantiago de los Caballeros
5h 00m
1 stop
TPA10:18 pmTampa
$277
Find similar
Spirit Airlines
Nov 15
TPA9:37 pmTampa
13h 45m
1 stop
STI12:22 pmSantiago de los Caballeros
Nov 17
STI1:17 pmSantiago de los Caballeros
10h 34m
1 stop
TPA10:51 pmTampa
$280
Find similar

American Airlines flights from Tampa to Santiago de los Caballeros

Our best American Airlines deals on Tampa to Santiago de los Caballeros flight tickets
American Airlines
Jan 15
TPA6:00 amTampa
14h 46m
1 stop
STI9:46 pmSantiago de los Caballeros
Jan 20
STI6:00 amSantiago de los Caballeros
12h 52m
1 stop
TPA5:52 pmTampa
$300
Find similar
American Airlines
Jan 15
TPA10:42 amTampa
10h 04m
1 stop
STI9:46 pmSantiago de los Caballeros
Jan 20
STI6:00 amSantiago de los Caballeros
16h 09m
2 stops
TPA9:09 pmTampa
$304
Find similar
American Airlines
Jan 7
TPA8:30 pmTampa
24h 16m
1 stop
STI9:46 pmSantiago de los Caballeros
Jan 27
STI4:33 pmSantiago de los Caballeros
18h 37m
2 stops
TPA10:10 amTampa
$310
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Tampa to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Tampa to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sat 11/15

9:37 pm-12:22 pm

1 stop13h 45m

Santiago de los Caballeros

Tue 11/18

1:17 pm-10:51 pm

1 stop10h 34m

$269

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Wed 12/10

8:11 pm-2:42 am

1 stop5h 31m

Santiago de los Caballeros

Wed 1/28

6:18 pm-10:18 pm

1 stop5h 00m

$277

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sat 11/15

9:37 pm-12:22 pm

1 stop13h 45m

Santiago de los Caballeros

Mon 11/17

1:17 pm-10:51 pm

1 stop10h 34m

$280

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Fri 11/14

6:45 am-12:22 pm

1 stop4h 37m

Santiago de los Caballeros

Sun 11/16

1:17 pm-10:51 pm

1 stop10h 34m

$297

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Thu 1/15

6:00 am-9:46 pm

1 stop14h 46m

Santiago de los Caballeros

Tue 1/20

6:00 am-5:52 pm

1 stop12h 52m

$300

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Thu 1/15

10:42 am-9:46 pm

1 stop10h 04m

Santiago de los Caballeros

Tue 1/20

6:00 am-9:09 pm

2 stops16h 09m

$304

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Fri 12/5

8:09 am-2:42 am

1 stop17h 33m

Santiago de los Caballeros

Tue 12/16

3:43 am-11:29 pm

2 stops20h 46m

$351

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sat 11/15

7:15 pm-1:06 pm

2 stops16h 51m

Santiago de los Caballeros

Tue 11/18

6:40 am-4:59 pm

2 stops11h 19m

$362

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sat 11/15

1:45 pm-12:59 am

2 stops10h 14m

Santiago de los Caballeros

Mon 11/17

9:01 pm-12:37 pm

2 stops16h 36m

$380

TampaSantiago de los Caballeros

TPA - STI

TPASTI

Tampa

Sat 1/24

6:00 am-3:45 pm

1 stop8h 45m

Santiago de los Caballeros

Sun 2/1

4:10 am-6:40 pm

1 stop15h 30m

$422

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santiago de los Caballeros from

How to get the cheapest flight ticket from Tampa to Santiago de los Caballeros

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago de los Caballeros?

The cheapest month to fly to Santiago de los Caballeros from Tampa is in October. Flight prices, which tend to average around $370, are often lower during this time because this is during the off-season. If you aren’t able to travel to Santiago de los Caballeros during the month of October, then flying in September is also cheap. Prices for this month can be found on momondo for an average of $436.

What is the cheapest day to depart on your flight to Santiago de los Caballeros?

The cheapest day to depart from Tampa to Santiago de los Caballeros is on a Thursday when prices can be found for as low as $423. When flying out on a Sunday, the most expensive travel day of the week, you can expect to see flight prices from Tampa to Santiago de los Caballeros for around $509.

What is the cheapest time of day to depart on your flight to Santiago de los Caballeros?

Our data shows that the cheapest Tampa to Santiago de los Caballeros flights are usually those with departure times in the evening. Our users have found flights to Santiago de los Caballeros in the evening for as low as $289. In the afternoon is when there is more demand to fly to Santiago de los Caballeros, so prices are often more expensive at around $718 per ticket.

How far in advance should I book a flight to Santiago de los Caballeros?

You are more likely to see cheaper flights to Santiago de los Caballeros from Tampa when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago de los Caballeros for around $546 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago de los Caballeros from Tampa for as low as $432 on momondo.

How have Tampa to Santiago de los Caballeros flight prices changed over time?

As of October 2025, prices for Tampa to Santiago de los Caballeros flights are approximately 33% more expensive when compared to flights at the same time last year.

When to book flights from Tampa to Santiago de los Caballeros

Are you open to changing your travel dates? Check out the ideal times to fly from Tampa to Santiago de los Caballeros according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Tampa to Santiago de los Caballeros (TPA to STI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Tampa to Santiago de los Caballeros

Direct flights

None
There are no direct flights from Tampa to Santiago de los Caballeros. There are no popular flight routes from Tampa to Santiago de los Caballeros.
Search flight deals

  • How far is Tampa to Santiago de los Caballeros by plane?

    Santiago de los Caballeros is 946.3 mi away from Tampa. A reasonable flight in good conditions will take 4h 22m.

  • When did momondo last update prices for flights from Tampa Airport to Santiago de los Caballeros Airport?

    Prices for flights from Tampa Airport to Santiago de los Caballeros Airport refresh daily.

  • How many operators does momondo search for flights from Tampa Airport to Santiago de los Caballeros Airport?

  • How old do you have to be to fly from Tampa Airport to Santiago de los Caballeros Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Tampa Airport to Santiago de los Caballeros Airport.

  • What documentation or ID do you need to fly to Santiago de los Caballeros Airport?

    The travel and health documents required for your trip to Santiago de los Caballeros Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago de los Caballeros Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Tampa to Santiago de los Caballeros?

Best airlines flying from Tampa to Santiago de los Caballeros

Compare and see reviews for airlines that fly from Tampa to Santiago de los Caballeros with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $313Free CancellationRating
6.3
8,110 reviews
Search Spirit Airlines flights
DeltaPriceFrom $348Free CancellationRating
7.9
7,996 reviews
Search Delta flights
American AirlinesPriceFrom $370Free CancellationRating
7.2
11,033 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Tampa to Santiago de los Caballeros?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santiago de los Caballeros from Tampa.

Can I find flights from Tampa to Santiago de los Caballeros with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santiago de los Caballeros from Tampa with this policy.

How can momondo help me find flights from Tampa to Santiago de los Caballeros?

momondo provides multiple filters to help you find the best flight to Santiago de los Caballeros from Tampa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Tampa to Santiago de los Caballeros right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santiago de los Caballeros, momondo offers a useful price alert feature which will track prices for flights to Santiago de los Caballeros from Tampa and alert you when they change.

An easier way to manage your Santiago de los Caballeros trip

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