What is the cheapest airline that flies from Lambert-St Louis to Santiago Arturo Merino Benitez?

American Airlines, Air Canada, and LATAM Airlines are the most popular carriers operating from Lambert-St Louis to Santiago Arturo Merino Benitez

Which layover airport has the shortest connection time from St. Louis to Santiago?

Atlanta (ATL) has the shortest average layover time for this route: 2h 05m.

Which layover airport has the shortest travel time from St. Louis to Santiago?

Flights connecting via Miami (MIA) have the shortest average one-way travel time: 12h 45m.

Which airport is the most popular layover for flights between St. Louis and Santiago?

Atlanta (ATL) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

What airlines fly to Santiago?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to Santiago from St. Louis according to our data. Delta is the first choice among our users, with 46% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 3 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport offers the lowest fares from St. Louis to Santiago?

Flights via Miami (MIA) offer the lowest average round-trip price of $898.

When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.

How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

As of September 2026, there are 3 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$653 Cheap Flights from St. Louis to Santiago in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from St. Louis to Santiago

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

4:49 pm - 7:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

11h 51m1 stop Atlanta Hartsfield-Jackson

9:45 am - 9:07 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

26h 22m2 stops Miami Atlanta Hartsfield-Jackson

$997LATAM Airlines

Fri, Dec 25 - Tue, Dec 29

6:00 am - 7:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

22h 40m1 stop Atlanta Hartsfield-Jackson

11:10 pm - 10:48 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

14h 38m1 stop Atlanta Hartsfield-Jackson

$1,005LATAM Airlines

Tue, Feb 16 - Wed, Mar 3

3:40 pm - 5:40 pmSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

23h 00m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl

9:50 pm - 8:12 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

13h 22m1 stop Atlanta Hartsfield-Jackson

$1,010LATAM Airlines

Mon, Feb 15 - Mon, Mar 1

7:03 am - 7:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

21h 37m1 stop Atlanta Hartsfield-Jackson

9:50 pm - 4:43 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

21h 53m1 stop Atlanta Hartsfield-Jackson

$1,015Delta

Tue, Dec 1 - Tue, Dec 15

6:15 am - 8:50 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

23h 35m1 stop Houston George Bush Intcntl

10:45 pm - 10:06 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

26h 21m1 stop Houston George Bush Intcntl

$1,025United Airlines

Mon, Feb 15 - Mon, Mar 1

12:36 pm - 6:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

15h 04m1 stop Atlanta Hartsfield-Jackson

11:00 pm - 1:15 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

17h 15m1 stop Atlanta Hartsfield-Jackson

$1,026Delta

Fri, Dec 11 - Thu, Dec 24

9:00 am - 7:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

19h 40m1 stop Atlanta Hartsfield-Jackson

9:50 pm - 8:52 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

14h 02m1 stop Atlanta Hartsfield-Jackson

$1,026Delta

Mon, Feb 1 - Sat, Feb 13

5:00 pm - 8:45 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

12h 45m1 stop Miami

10:30 pm - 10:08 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

14h 38m1 stop Miami

$1,064American Airlines

Wed, Nov 4 - Wed, Nov 11

5:00 pm - 8:45 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

12h 45m1 stop Miami

10:30 pm - 12:28 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

16h 58m2 stops Miami Dallas/Fort Worth

$1,069American Airlines

Wed, Nov 4 - Wed, Nov 11

6:50 pm - 7:50 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

35h 00m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

10:45 pm - 4:59 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

21h 14m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$1,082United Airlines

Thu, Oct 29 - Mon, Nov 2

Cheap last minute flights

Enter your travel dates to find the best prices.

12:00 pm - 5:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

15h 40m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl

12:05 am - 7:56 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

21h 51m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$1,037LATAM Airlines

Fri, Sep 25 - Fri, Oct 23

6:00 am - 5:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

21h 40m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl

8:40 pm - 9:09 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

14h 29m1 stop Atlanta Hartsfield-Jackson

$1,063LATAM Airlines

Fri, Sep 25 - Sat, Oct 24

12:00 pm - 5:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

15h 40m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl

8:40 am - 6:15 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

35h 35m3 stops Punta Cana Miami Atlanta Hartsfield-Jackson

$1,094LATAM Airlines

Fri, Sep 25 - Sat, Oct 24

4:59 pm - 10:15 pmSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

27h 16m3 stops Atlanta Hartsfield-Jackson Miami Punta Cana

8:55 pm - 10:55 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

16h 00m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

$1,107LATAM Airlines

Thu, Sep 24 - Thu, Oct 1

4:59 pm - 10:15 pmSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

27h 16m3 stops Atlanta Hartsfield-Jackson Miami Punta Cana

9:30 am - 10:55 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

27h 25m3 stops Buenos Aires Ministro Pistarini Miami Atlanta Hartsfield-Jackson

$1,113LATAM Airlines

Thu, Sep 24 - Thu, Oct 1

2:11 pm - 8:00 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

15h 49m1 stop Miami

9:30 pm - 1:21 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

17h 51m1 stop Miami

$1,117American Airlines

Thu, Sep 24 - Thu, Oct 1

10:21 am - 8:00 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

19h 39m2 stops Charlotte Douglas Miami

9:30 pm - 1:21 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

17h 51m1 stop Miami

$1,122American Airlines

Thu, Sep 24 - Thu, Oct 1

11:09 am - 8:00 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

18h 51m2 stops Philadelphia Miami

9:30 pm - 2:44 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

19h 14m2 stops Miami Dallas/Fort Worth

$1,122American Airlines

Thu, Sep 24 - Thu, Oct 1

12:00 pm - 8:15 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

18h 15m1 stop Atlanta Hartsfield-Jackson

8:40 pm - 10:51 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

16h 11m1 stop Atlanta Hartsfield-Jackson

$1,312LATAM Airlines

Fri, Sep 25 - Sat, Oct 24

2:40 pm - 9:55 pmSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

29h 15m3 stops Toronto Pearson Intl Bogotá El Dorado Lima J Chavez Intl

7:40 am - 3:26 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

33h 46m3 stops Bogotá El Dorado Cancun Toronto Pearson Intl

$2,525Multiple Airlines

Fri, Sep 25 - Sat, Oct 24

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LATAM Airlines flights from St. Louis to Santiago

Our best LATAM Airlines deals on St. Louis to Santiago flight tickets

LATAM Airlines

Dec 25

STL4:49 pmLambert-St Louis

11h 51m

1 stop

SCL7:40 amSantiago Arturo Merino Benitez

Dec 29

SCL9:45 amSantiago Arturo Merino Benitez

26h 22m

2 stops

STL9:07 amLambert-St Louis

$997

LATAM Airlines

Feb 16

STL6:00 amLambert-St Louis

22h 40m

1 stop

SCL7:40 amSantiago Arturo Merino Benitez

Mar 3

SCL11:10 pmSantiago Arturo Merino Benitez

14h 38m

1 stop

STL10:48 amLambert-St Louis

$1,005

LATAM Airlines

Feb 15

STL3:40 pmLambert-St Louis

23h 00m

2 stops

SCL5:40 pmSantiago Arturo Merino Benitez

Mar 1

SCL9:50 pmSantiago Arturo Merino Benitez

13h 22m

1 stop

STL8:12 amLambert-St Louis

$1,010

Delta flights from St. Louis to Santiago

Our best Delta deals on St. Louis to Santiago flight tickets

Delta

Dec 1

STL7:03 amLambert-St Louis

21h 37m

1 stop

SCL7:40 amSantiago Arturo Merino Benitez

Dec 15

SCL9:50 pmSantiago Arturo Merino Benitez

21h 53m

1 stop

STL4:43 pmLambert-St Louis

$1,015

Delta

Dec 11

STL12:36 pmLambert-St Louis

15h 04m

1 stop

SCL6:40 amSantiago Arturo Merino Benitez

Dec 24

SCL11:00 pmSantiago Arturo Merino Benitez

17h 15m

1 stop

STL1:15 pmLambert-St Louis

$1,026

Delta

Feb 20

STL3:40 pmLambert-St Louis

20h 20m

2 stops

SCL3:00 pmSantiago Arturo Merino Benitez

Mar 6

SCL9:50 pmSantiago Arturo Merino Benitez

19h 53m

1 stop

STL2:43 pmLambert-St Louis

$1,037

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Fri 12/25

4:49 pm-7:40 am

1 stop11h 51m

Santiago Arturo Merino Benitez

Tue 12/29

9:45 am-9:07 am

2 stops26h 22m

$997

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Tue 2/16

6:00 am-7:40 am

1 stop22h 40m

Santiago Arturo Merino Benitez

Wed 3/3

11:10 pm-10:48 am

1 stop14h 38m

$1,005

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Mon 2/15

3:40 pm-5:40 pm

2 stops23h 00m

Santiago Arturo Merino Benitez

Mon 3/1

9:50 pm-8:12 am

1 stop13h 22m

$1,010

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Tue 12/1

7:03 am-7:40 am

1 stop21h 37m

Santiago Arturo Merino Benitez

Tue 12/15

9:50 pm-4:43 pm

1 stop21h 53m

$1,015

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Mon 2/15

6:15 am-8:50 am

1 stop23h 35m

Santiago Arturo Merino Benitez

Mon 3/1

10:45 pm-10:06 pm

1 stop26h 21m

$1,025

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Fri 12/11

12:36 pm-6:40 am

1 stop15h 04m

Santiago Arturo Merino Benitez

Thu 12/24

11:00 pm-1:15 pm

1 stop17h 15m

$1,026

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Mon 2/1

9:00 am-7:40 am

1 stop19h 40m

Santiago Arturo Merino Benitez

Sat 2/13

9:50 pm-8:52 am

1 stop14h 02m

$1,026

Quickest round-trip

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Wed 11/4

5:00 pm-8:45 am

1 stop12h 45m

Santiago Arturo Merino Benitez

Wed 11/11

10:30 pm-10:08 am

1 stop14h 38m

$1,064

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Wed 11/4

5:00 pm-8:45 am

1 stop12h 45m

Santiago Arturo Merino Benitez

Wed 11/11

10:30 pm-12:28 pm

2 stops16h 58m

$1,069

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Thu 10/29

6:50 pm-7:50 am

2 stops35h 00m

Santiago Arturo Merino Benitez

Mon 11/2

10:45 pm-4:59 pm

2 stops21h 14m

$1,082

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the cheapest month to fly to Santiago?

In general, March is the cheapest month to fly from St. Louis to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $764. If you don’t want to visit Santiago in March, then you should wait until December to fly from St. Louis, when ticket prices are also cheap, with an average price of $944.

When to book flights from St. Louis to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to Santiago (STL to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santiago

Best Price Found	$653
Fastest flight time	19h 00m
Direct flights	None

The best one-way flight to Santiago from St. Louis in the past 72 hours is $653. The best round-trip flight deal from St. Louis to Santiago found on momondo in the last 72 hours is $997.

The fastest flight from St. Louis to Santiago takes 19h 00m

There are no direct flights from St. Louis to Santiago. There are no popular flight routes from St. Louis to Santiago.

Search flight deals

Frequently asked questions about flying from St. Louis to Santiago

How far is Lambert-St Louis to Santiago Arturo Merino Benitez by plane?
The distance between Lambert-St Louis and Santiago Arturo Merino Benitez is about 5131.6 mi. Typically, this will take 19h 00m by plane in normal conditions.
When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.
How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
As of September 2026, there are 3 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from St. Louis to Santiago?
Based on momondo bookings for flights between St. Louis and Santiago, the leading airline is Delta, making up 46% of the total bookings. Other popular airlines include American Airlines with 30% and LATAM Airlines with 24%.

Best airlines flying from St. Louis to Santiago

Compare and see reviews for airlines that fly from St. Louis to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $611	Free Cancellation	Rating 7.8 8,597 reviews	Search Delta flights
American Airlines	PriceFrom $689	Free Cancellation	Rating 7.0 12,082 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $792	Free Cancellation	Rating 7.4 1,980 reviews	Search LATAM Airlines flights

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Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santiago?

Finding the right flight to Santiago from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from St. Louis to Santiago with flexible booking policies on momondo?

Flights from St. Louis to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from St. Louis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from St. Louis to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.