What is the cheapest airline that flies from Lambert-St Louis to Santiago Arturo Merino Benitez?

JetBlue and LATAM Airlines are the most popular carriers operating from Lambert-St Louis to Santiago Arturo Merino Benitez

Which layover airport offers the lowest fares from St. Louis to Santiago?

Flights via Miami (MIA) offer the lowest average round-trip price of $898.

Which airport is the most popular layover for flights between St. Louis and Santiago?

Atlanta (ATL) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest connection time from St. Louis to Santiago?

Atlanta (ATL) has the shortest average layover time for this route: 2h 05m.

What airlines fly to Santiago?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to Santiago from St. Louis according to our data. Delta is the first choice among our users, with 44% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 3 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Which layover airport has the shortest travel time from St. Louis to Santiago?

Flights connecting via Miami (MIA) have the shortest average one-way travel time: 12h 45m.

When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.

How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

As of August 2026, there are 3 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$361 Cheap Flights from St. Louis to Santiago in 2026

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from St. Louis to Santiago

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:00 am - 7:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

22h 40m1 stop Atlanta Hartsfield-Jackson

11:10 pm - 11:15 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

15h 05m1 stop Atlanta Hartsfield-Jackson

$876JetBlue

Sat, Oct 31 - Tue, Nov 10

10:00 am - 7:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

18h 40m1 stop Atlanta Hartsfield-Jackson

9:50 pm - 11:15 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

16h 25m1 stop Atlanta Hartsfield-Jackson

$986LATAM Airlines

Tue, Nov 17 - Tue, Dec 15

10:38 am - 9:00 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

19h 22m1 stop Miami

10:15 pm - 10:11 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

14h 56m1 stop Miami

$995American Airlines

Sun, Nov 15 - Sun, Nov 22

5:00 pm - 9:00 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

13h 00m1 stop Miami

11:45 pm - 8:19 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

23h 34m1 stop Dallas/Fort Worth

$995American Airlines

Tue, Nov 17 - Tue, Dec 15

10:00 am - 7:15 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

18h 15m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

5:55 pm - 8:53 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

17h 58m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

$995LATAM Airlines

Tue, Nov 17 - Tue, Dec 15

2:31 pm - 7:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

14h 09m1 stop Atlanta Hartsfield-Jackson

11:10 pm - 4:32 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

20h 22m2 stops Miami Atlanta Hartsfield-Jackson

$995LATAM Airlines

Tue, Nov 17 - Tue, Dec 15

6:50 pm - 8:50 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

35h 00m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

10:45 pm - 4:51 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

21h 06m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$1,000United Airlines

Sun, Nov 1 - Thu, Nov 12

6:50 pm - 8:50 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

35h 00m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

10:45 pm - 4:46 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

21h 01m1 stop Houston George Bush Intcntl

$1,000United Airlines

Sun, Nov 1 - Thu, Nov 12

3:40 pm - 7:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

13h 00m1 stop Atlanta Hartsfield-Jackson

11:00 pm - 2:43 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

18h 43m1 stop Atlanta Hartsfield-Jackson

$1,035Delta

Thu, Jan 7 - Sat, Jan 23

5:46 pm - 3:00 pmSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

19h 14m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl

8:55 pm - 1:52 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

18h 57m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

$1,047Delta

Thu, Sep 10 - Thu, Sep 17

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LATAM Airlines flights from St. Louis to Santiago

Our best LATAM Airlines deals on St. Louis to Santiago flight tickets

LATAM Airlines

Nov 17

STL10:00 amLambert-St Louis

18h 40m

1 stop

SCL7:40 amSantiago Arturo Merino Benitez

Dec 15

SCL9:50 pmSantiago Arturo Merino Benitez

16h 25m

1 stop

STL11:15 amLambert-St Louis

$986

LATAM Airlines

Nov 17

STL2:31 pmLambert-St Louis

14h 09m

1 stop

SCL7:40 amSantiago Arturo Merino Benitez

Dec 15

SCL11:10 pmSantiago Arturo Merino Benitez

20h 22m

2 stops

STL4:32 pmLambert-St Louis

$995

LATAM Airlines

Oct 31

STL4:00 pmLambert-St Louis

59h 35m

2 stops

SCL5:35 amSantiago Arturo Merino Benitez

Nov 10

SCL11:10 pmSantiago Arturo Merino Benitez

15h 05m

1 stop

STL11:15 amLambert-St Louis

$1,012

American Airlines flights from St. Louis to Santiago

Our best American Airlines deals on St. Louis to Santiago flight tickets

American Airlines

Sep 28

STL2:11 pmLambert-St Louis

15h 49m

1 stop

SCL8:00 amSantiago Arturo Merino Benitez

Oct 5

SCL9:30 pmSantiago Arturo Merino Benitez

22h 19m

1 stop

STL5:49 pmLambert-St Louis

$1,021

American Airlines

Sep 30

STL5:10 pmLambert-St Louis

12h 50m

1 stop

SCL8:00 amSantiago Arturo Merino Benitez

Oct 7

SCL9:30 pmSantiago Arturo Merino Benitez

21h 57m

1 stop

STL5:27 pmLambert-St Louis

$1,022

American Airlines

Sep 28

STL2:11 pmLambert-St Louis

15h 49m

1 stop

SCL8:00 amSantiago Arturo Merino Benitez

Oct 5

SCL9:30 pmSantiago Arturo Merino Benitez

20h 18m

2 stops

STL3:48 pmLambert-St Louis

$1,026

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Sat 10/31

7:00 am-7:40 am

1 stop22h 40m

Santiago Arturo Merino Benitez

Tue 11/10

11:10 pm-11:15 am

1 stop15h 05m

$876

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Tue 11/17

10:00 am-7:40 am

1 stop18h 40m

Santiago Arturo Merino Benitez

Tue 12/15

9:50 pm-11:15 am

1 stop16h 25m

$986

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Sun 11/15

10:38 am-9:00 am

1 stop19h 22m

Santiago Arturo Merino Benitez

Sun 11/22

10:15 pm-10:11 am

1 stop14h 56m

$995

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Tue 11/17

5:00 pm-9:00 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Tue 12/15

11:45 pm-8:19 pm

1 stop23h 34m

$995

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Tue 11/17

10:00 am-7:15 am

2 stops18h 15m

Santiago Arturo Merino Benitez

Tue 12/15

5:55 pm-8:53 am

2 stops17h 58m

$995

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Tue 11/17

2:31 pm-7:40 am

1 stop14h 09m

Santiago Arturo Merino Benitez

Tue 12/15

11:10 pm-4:32 pm

2 stops20h 22m

$995

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Sun 11/1

6:50 pm-8:50 am

2 stops35h 00m

Santiago Arturo Merino Benitez

Thu 11/12

10:45 pm-4:51 pm

2 stops21h 06m

$1,000

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Sun 11/1

6:50 pm-8:50 am

2 stops35h 00m

Santiago Arturo Merino Benitez

Thu 11/12

10:45 pm-4:46 pm

1 stop21h 01m

$1,000

Quickest round-trip

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Thu 1/7

3:40 pm-7:40 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Sat 1/23

11:00 pm-2:43 pm

1 stop18h 43m

$1,035

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Thu 9/10

5:46 pm-3:00 pm

2 stops19h 14m

Santiago Arturo Merino Benitez

Thu 9/17

8:55 pm-1:52 pm

2 stops18h 57m

$1,047

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between St. Louis and Santiago?

Prices are currently low for flights on this route.

Typical prices usually range from $1,234 to $1,382.
The lowest price recently found on this route was $876.

What is the cheapest month to fly to Santiago?

In general, March is the cheapest month to fly from St. Louis to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $823. If you don’t want to visit Santiago in March, then you should wait until December to fly from St. Louis, when ticket prices are also cheap, with an average price of $944.

When to book flights from St. Louis to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to Santiago (STL to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santiago

Best Price Found	$361
Fastest flight time	15h 49m
Direct flights	None

The best one-way flight to Santiago from St. Louis in the past 72 hours is $361. The best round-trip flight deal from St. Louis to Santiago found on momondo in the last 72 hours is $876.

The fastest flight from St. Louis to Santiago takes 15h 49m

There are no direct flights from St. Louis to Santiago. There are no popular flight routes from St. Louis to Santiago.

Search flight deals

Frequently asked questions about flying from St. Louis to Santiago

How far is Lambert-St Louis to Santiago Arturo Merino Benitez by plane?
The distance between Lambert-St Louis and Santiago Arturo Merino Benitez is about 5131.6 mi. Typically, this will take 15h 49m by plane in normal conditions.
When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.
How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
As of August 2026, there are 3 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from St. Louis to Santiago?
Based on momondo bookings for flights between St. Louis and Santiago, the leading airline is Delta, making up 44% of the total bookings. Other popular airlines include American Airlines with 33% and LATAM Airlines with 23%.

Best airlines flying from St. Louis to Santiago

Compare and see reviews for airlines that fly from St. Louis to Santiago with momondo

Airline	Rating	Free Cancellation	Price
Delta	PriceFrom $611	Free Cancellation	Rating 7.8 8,503 reviews	Search Delta flights
American Airlines	PriceFrom $689	Free Cancellation	Rating 7.1 11,948 reviews	Search American Airlines flights
LATAM Airlines	PriceFrom $792	Free Cancellation	Rating 7.4 1,986 reviews	Search LATAM Airlines flights

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Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santiago?

Finding the right flight to Santiago from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from St. Louis to Santiago with flexible booking policies on momondo?

Flights from St. Louis to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from St. Louis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from St. Louis to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.