What airlines fly to Santiago?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to Santiago from St. Louis according to our data. Delta is the first choice among our users, with 37% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 3 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.

How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

As of January 2026, there are 3 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$761 Cheap Flights from St. Louis to Santiago in 2026

Q: What is the typical price of a round-trip flight between St. Louis and Santiago?

Prices are currently low for flights on this route. Typical prices usually range from $894 to $2,001. The lowest price recently found on this route was $761.

1 adult

0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

Find the cheapest flights from St. Louis to Santiago

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

7:03 am - 7:40 am

STL

SCL

22h 37m1 stop

10:10 pm - 9:05 am

SCL

STL

12h 55m1 stop

$761LATAM Airlines

Wed, Mar 11 - Mon, Mar 23

5:04 pm - 2:55 pm

STL

SCL

18h 51m2 stops

6:30 pm - 9:06 am

SCL

STL

17h 36m2 stops

$763LATAM Airlines

Wed, Feb 4 - Wed, Feb 18

5:21 pm - 7:40 am

STL

SCL

12h 19m1 stop

10:10 pm - 5:53 pm

SCL

STL

21h 43m1 stop

$765Delta

Wed, Mar 11 - Mon, Mar 23

6:59 pm - 2:05 pm

STL

SCL

17h 06m2 stops

5:15 am - 11:58 pm

SCL

STL

20h 43m2 stops

$769LATAM Airlines

Wed, Mar 11 - Mon, Mar 23

12:04 pm - 2:10 pm

STL

SCL

24h 06m3 stops

4:35 am - 11:58 pm

SCL

STL

21h 23m2 stops

$770LATAM Airlines

Mon, Mar 9 - Tue, Mar 24

10:13 am - 7:40 am

STL

SCL

18h 27m1 stop

11:10 pm - 5:42 pm

SCL

STL

21h 32m1 stop

$779LATAM Airlines

Thu, Feb 19 - Thu, Feb 26

4:51 pm - 8:20 pm

STL

SCL

49h 29m2 stops

4:20 pm - 9:49 am

SCL

STL

43h 29m3 stops

$795Multiple Airlines

Wed, Mar 11 - Mon, Mar 23

12:04 pm - 2:10 pm

STL

SCL

24h 06m3 stops

8:30 am - 11:09 am

SCL

STL

28h 39m3 stops

$800LATAM Airlines

Tue, Mar 17 - Tue, Mar 31

6:04 am - 6:45 am

STL

SCL

22h 41m2 stops

8:45 am - 11:58 pm

SCL

STL

17h 13m2 stops

$803LATAM Airlines

Fri, Mar 20 - Mon, Mar 30

10:12 am - 6:45 am

STL

SCL

18h 33m2 stops

8:45 pm - 11:09 am

SCL

STL

16h 24m2 stops

$805Delta

Fri, Mar 20 - Mon, Mar 30

Delta flights from St. Louis to Santiago

Our best Delta deals on St. Louis to Santiago flight tickets

Delta

Mar 11

STL5:21 pmLambert-St Louis

12h 19m

1 stop

SCL7:40 amSantiago Arturo Merino Benitez

Mar 23

SCL10:10 pmSantiago Arturo Merino Benitez

14h 59m

1 stop

STL11:09 amLambert-St Louis

$765

Find similar

Delta

Mar 20

STL10:12 amLambert-St Louis

19h 28m

1 stop

SCL7:40 amSantiago Arturo Merino Benitez

Mar 30

SCL8:45 pmSantiago Arturo Merino Benitez

16h 24m

2 stops

STL11:09 amLambert-St Louis

$805

Find similar

Delta

Feb 20

STL3:47 pmLambert-St Louis

20h 43m

2 stops

SCL3:30 pmSantiago Arturo Merino Benitez

Mar 2

SCL6:30 pmSantiago Arturo Merino Benitez

17h 36m

2 stops

STL9:06 amLambert-St Louis

$935

Find similar

American Airlines flights from St. Louis to Santiago

Our best American Airlines deals on St. Louis to Santiago flight tickets

American Airlines

Mar 21

STL1:30 pmLambert-St Louis

17h 35m

2 stops

SCL9:05 amSantiago Arturo Merino Benitez

Mar 28

SCL9:15 pmSantiago Arturo Merino Benitez

15h 17m

1 stop

STL10:32 amLambert-St Louis

$850

Find similar

American Airlines

Mar 20

STL10:33 amLambert-St Louis

18h 27m

2 stops

SCL7:00 amSantiago Arturo Merino Benitez

Mar 30

SCL9:25 pmSantiago Arturo Merino Benitez

20h 03m

2 stops

STL3:28 pmLambert-St Louis

$903

Find similar

American Airlines

Apr 10

STL11:06 amLambert-St Louis

18h 44m

1 stop

SCL6:50 amSantiago Arturo Merino Benitez

Apr 18

SCL8:30 pmSantiago Arturo Merino Benitez

14h 46m

1 stop

STL10:16 amLambert-St Louis

$955

Find similar

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

7:03 am-7:40 am

1 stop22h 37m

Santiago Arturo Merino Benitez

Mon 3/23

10:10 pm-9:05 am

1 stop12h 55m

$761

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 2/4

5:04 pm-2:55 pm

2 stops18h 51m

Santiago Arturo Merino Benitez

Wed 2/18

6:30 pm-9:06 am

2 stops17h 36m

$763

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

5:21 pm-7:40 am

1 stop12h 19m

Santiago Arturo Merino Benitez

Mon 3/23

10:10 pm-5:53 pm

1 stop21h 43m

$765

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

6:59 pm-2:05 pm

2 stops17h 06m

Santiago Arturo Merino Benitez

Mon 3/23

5:15 am-11:58 pm

2 stops20h 43m

$769

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Mon 3/9

12:04 pm-2:10 pm

3 stops24h 06m

Santiago Arturo Merino Benitez

Tue 3/24

4:35 am-11:58 pm

2 stops21h 23m

$770

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 2/19

10:13 am-7:40 am

1 stop18h 27m

Santiago Arturo Merino Benitez

Thu 2/26

11:10 pm-5:42 pm

1 stop21h 32m

$779

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

4:51 pm-8:20 pm

2 stops49h 29m

Santiago Arturo Merino Benitez

Mon 3/23

4:20 pm-9:49 am

3 stops43h 29m

$795

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Tue 3/17

12:04 pm-2:10 pm

3 stops24h 06m

Santiago Arturo Merino Benitez

Tue 3/31

8:30 am-11:09 am

3 stops28h 39m

$800

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Fri 3/20

6:04 am-6:45 am

2 stops22h 41m

Santiago Arturo Merino Benitez

Mon 3/30

8:45 am-11:58 pm

2 stops17h 13m

$803

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Fri 3/20

10:12 am-6:45 am

2 stops18h 33m

Santiago Arturo Merino Benitez

Mon 3/30

8:45 pm-11:09 am

2 stops16h 24m

$805

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between St. Louis and Santiago?

What is the cheapest month to fly to Santiago?

In general, March is the cheapest month to fly from St. Louis to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $868. If you don’t want to visit Santiago in March, then you should wait until July to fly from St. Louis, when ticket prices are also cheap, with an average price of $883.

When to book flights from St. Louis to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to Santiago (STL to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santiago

Fastest flight time	16h 25m
Direct flights	None

The fastest flight from St. Louis to Santiago takes 16h 25m

There are no direct flights from St. Louis to Santiago. There are no popular flight routes from St. Louis to Santiago.

Search flight deals

How far is Lambert-St Louis to Santiago Arturo Merino Benitez by plane?
The distance between Lambert-St Louis and Santiago Arturo Merino Benitez is about 5131.6 mi. Typically, this will take 16h 25m by plane in normal conditions.
When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.
How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
As of January 2026, there are 3 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from St. Louis to Santiago?
Based on momondo bookings for flights between St. Louis and Santiago, the leading airline is Delta, making up 37% of the total bookings. Other popular airlines include American Airlines with 33% and LATAM Airlines with 31%.

Best airlines flying from St. Louis to Santiago

Compare and see reviews for airlines that fly from St. Louis to Santiago with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $689	Free Cancellation	Rating 7.2 11,090 reviews	Search American Airlines flights
Delta	PriceFrom $755	Free Cancellation	Rating 7.9 8,021 reviews	Search Delta flights
LATAM Airlines	PriceFrom $803	Free Cancellation	Rating 7.5 1,897 reviews	Search LATAM Airlines flights

Viña del Mar

Valparaíso

Santa Cruz

Valle Nevado

San Fernando

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santiago?

Finding the right flight to Santiago from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from St. Louis to Santiago with flexible booking policies on momondo?

Flights from St. Louis to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from St. Louis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from St. Louis to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.