What airlines fly to Santiago?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to Santiago from St. Louis according to our data. Delta is the first choice among our users, with 37% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 3 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.

How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

As of January 2026, there are 3 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$846 Cheap Flights from St. Louis to Santiago in 2026

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11:25 am - 7:50 am

STL

SCL

18h 25m

2 stops

9:45 pm - 9:21 am

SCL

STL

13h 36m

1 stop

$846United Airlines

Wed, Mar 11 - Mon, Mar 23

7:40 am - 7:50 am

STL

SCL

22h 10m

2 stops

9:45 pm - 9:07 pm

SCL

STL

25h 22m

2 stops

$849United Airlines

Wed, Mar 11 - Mon, Mar 23

7:00 am - 8:05 am

STL

SCL

22h 05m

1 stop

10:15 pm - 5:13 pm

SCL

STL

20h 58m

1 stop

$858American Airlines

Mon, Mar 2 - Mon, Mar 23

6:20 pm - 9:05 am

STL

SCL

12h 45m

1 stop

9:20 pm - 10:32 am

SCL

STL

15h 12m

1 stop

$859American Airlines

Wed, Mar 11 - Mon, Mar 23

11:55 am - 2:30 pm

STL

SCL

23h 35m

3 stops

4:35 am - 11:58 pm

SCL

STL

21h 23m

2 stops

$863LATAM Airlines

Thu, Mar 5 - Thu, Mar 12

5:00 pm - 7:40 am

STL

SCL

11h 40m

1 stop

6:30 pm - 11:02 am

SCL

STL

19h 32m

2 stops

$873LATAM Airlines

Wed, Feb 18 - Tue, Feb 24

9:55 am - 8:50 am

STL

SCL

19h 55m

2 stops

10:45 pm - 2:29 pm

SCL

STL

18h 44m

2 stops

$878United Airlines

Wed, Feb 18 - Tue, Feb 24

11:55 am - 2:30 pm

STL

SCL

23h 35m

3 stops

7:15 am - 11:09 am

SCL

STL

29h 54m

3 stops

$893LATAM Airlines

Thu, Mar 5 - Thu, Mar 12

4:21 pm - 7:40 am

STL

SCL

13h 19m

1 stop

11:00 pm - 5:53 pm

SCL

STL

20h 53m

2 stops

$895LATAM Airlines

Fri, Mar 20 - Mon, Mar 30

4:21 pm - 7:40 am

STL

SCL

13h 19m

1 stop

10:10 pm - 9:02 am

SCL

STL

12h 52m

1 stop

$898LATAM Airlines

Mon, Mar 9 - Fri, Mar 20

LATAM Airlines flights from St. Louis to Santiago

Our best LATAM Airlines deals on St. Louis to Santiago flight tickets

LATAM Airlines

Mar 5

STL11:55 amLambert-St Louis

23h 35m

3 stops

SCL2:30 pmSantiago Arturo Merino Benitez

Mar 12

SCL4:35 amSantiago Arturo Merino Benitez

21h 23m

2 stops

STL11:58 pmLambert-St Louis

$863

LATAM Airlines

Feb 18

STL5:00 pmLambert-St Louis

11h 40m

1 stop

SCL7:40 amSantiago Arturo Merino Benitez

Feb 24

SCL6:30 pmSantiago Arturo Merino Benitez

19h 32m

2 stops

STL11:02 amLambert-St Louis

$873

LATAM Airlines

Mar 5

STL11:55 amLambert-St Louis

23h 35m

3 stops

SCL2:30 pmSantiago Arturo Merino Benitez

Mar 12

SCL7:15 amSantiago Arturo Merino Benitez

29h 54m

3 stops

STL11:09 amLambert-St Louis

$893

United Airlines flights from St. Louis to Santiago

Our best United Airlines deals on St. Louis to Santiago flight tickets

United Airlines

Mar 11

STL11:25 amLambert-St Louis

18h 25m

2 stops

SCL7:50 amSantiago Arturo Merino Benitez

Mar 23

SCL9:45 pmSantiago Arturo Merino Benitez

13h 36m

1 stop

STL9:21 amLambert-St Louis

$846

United Airlines

Mar 11

STL7:40 amLambert-St Louis

22h 10m

2 stops

SCL7:50 amSantiago Arturo Merino Benitez

Mar 23

SCL9:45 pmSantiago Arturo Merino Benitez

25h 22m

2 stops

STL9:07 pmLambert-St Louis

$849

United Airlines

Feb 18

STL9:55 amLambert-St Louis

19h 55m

2 stops

SCL8:50 amSantiago Arturo Merino Benitez

Feb 24

SCL10:45 pmSantiago Arturo Merino Benitez

18h 44m

2 stops

STL2:29 pmLambert-St Louis

$878

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

11:25 am-7:50 am

2 stops18h 25m

Santiago Arturo Merino Benitez

Mon 3/23

9:45 pm-9:21 am

1 stop13h 36m

$846

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

7:40 am-7:50 am

2 stops22h 10m

Santiago Arturo Merino Benitez

Mon 3/23

9:45 pm-9:07 pm

2 stops25h 22m

$849

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Mon 3/2

7:00 am-8:05 am

1 stop22h 05m

Santiago Arturo Merino Benitez

Mon 3/23

10:15 pm-5:13 pm

1 stop20h 58m

$858

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

6:20 pm-9:05 am

1 stop12h 45m

Santiago Arturo Merino Benitez

Mon 3/23

9:20 pm-10:32 am

1 stop15h 12m

$859

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 3/5

11:55 am-2:30 pm

3 stops23h 35m

Santiago Arturo Merino Benitez

Thu 3/12

4:35 am-11:58 pm

2 stops21h 23m

$863

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 2/18

5:00 pm-7:40 am

1 stop11h 40m

Santiago Arturo Merino Benitez

Tue 2/24

6:30 pm-11:02 am

2 stops19h 32m

$873

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 2/18

9:55 am-8:50 am

2 stops19h 55m

Santiago Arturo Merino Benitez

Tue 2/24

10:45 pm-2:29 pm

2 stops18h 44m

$878

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 3/5

11:55 am-2:30 pm

3 stops23h 35m

Santiago Arturo Merino Benitez

Thu 3/12

7:15 am-11:09 am

3 stops29h 54m

$893

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Fri 3/20

4:21 pm-7:40 am

1 stop13h 19m

Santiago Arturo Merino Benitez

Mon 3/30

11:00 pm-5:53 pm

2 stops20h 53m

$895

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Mon 3/9

4:21 pm-7:40 am

1 stop13h 19m

Santiago Arturo Merino Benitez

Fri 3/20

10:10 pm-9:02 am

1 stop12h 52m

$898

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Santiago?

In general, March is the cheapest month to fly from St. Louis to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $868. If you don’t want to visit Santiago in March, then you should wait until July to fly from St. Louis, when ticket prices are also cheap, with an average price of $883.

When to book flights from St. Louis to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to Santiago (STL to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santiago

Fastest flight time	11h 40m
Direct flights	None

The fastest flight from St. Louis to Santiago takes 11h 40m

There are no direct flights from St. Louis to Santiago. There are no popular flight routes from St. Louis to Santiago.

Search flight deals

How far is Lambert-St Louis to Santiago Arturo Merino Benitez by plane?
The distance between Lambert-St Louis and Santiago Arturo Merino Benitez is about 5131.6 mi. Typically, this will take 11h 40m by plane in normal conditions.
When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.
How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
As of January 2026, there are 3 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from St. Louis to Santiago?
Based on momondo bookings for flights between St. Louis and Santiago, the leading airline is Delta, making up 37% of the total bookings. Other popular airlines include American Airlines with 32% and LATAM Airlines with 31%.

Best airlines flying from St. Louis to Santiago

Compare and see reviews for airlines that fly from St. Louis to Santiago with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $689	Free Cancellation	Rating 7.2 11,173 reviews	Search American Airlines flights
Delta	PriceFrom $755	Free Cancellation	Rating 7.9 8,087 reviews	Search Delta flights
LATAM Airlines	PriceFrom $803	Free Cancellation	Rating 7.5 1,913 reviews	Search LATAM Airlines flights

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Santa Cruz

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San Fernando

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Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santiago?

Finding the right flight to Santiago from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from St. Louis to Santiago with flexible booking policies on momondo?

Flights from St. Louis to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from St. Louis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from St. Louis to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.