What is the cheapest airline that flies from Lambert-St Louis to Santiago Arturo Merino Benitez?

LATAM Airlines and Air Canada are the most popular carriers operating from Lambert-St Louis to Santiago Arturo Merino Benitez

What airlines fly to Santiago?

Delta, LATAM Airlines and American Airlines are the top three most popular airlines that fly to Santiago from St. Louis according to our data. Delta is the first choice among our users, with 32% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 4 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.

How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

As of December 2025, there are 4 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$356 Cheap Flights from St. Louis to Santiago in 2025/26

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10:00 am - 7:50 am

STL

SCL

19h 50m2 stops

9:45 pm - 9:21 am

SCL

STL

13h 36m1 stop

$752United Airlines

Wed, Mar 11 - Mon, Mar 23

5:00 am - 7:50 am

STL

SCL

24h 50m2 stops

9:45 pm - 9:21 am

SCL

STL

13h 36m1 stop

$755United Airlines

Wed, Mar 11 - Mon, Mar 23

5:00 pm - 2:05 pm

STL

SCL

19h 05m2 stops

4:35 am - 11:42 pm

SCL

STL

21h 07m2 stops

$761LATAM Airlines

Wed, Mar 11 - Mon, Mar 23

5:00 pm - 2:05 pm

STL

SCL

19h 05m2 stops

5:15 am - 11:42 pm

SCL

STL

20h 27m2 stops

$764LATAM Airlines

Wed, Mar 11 - Mon, Mar 23

10:02 am - 6:35 am

STL

SCL

18h 33m2 stops

12:25 am - 9:10 pm

SCL

STL

22h 45m2 stops

$804Delta

Fri, Mar 20 - Sun, Mar 29

3:58 pm - 5:55 pm

STL

SCL

23h 57m2 stops

10:25 pm - 11:42 pm

SCL

STL

27h 17m2 stops

$859LATAM Airlines

Mon, Mar 9 - Fri, Mar 20

7:10 am - 5:45 am

STL

SCL

21h 35m2 stops

4:50 pm - 10:45 am

SCL

STL

18h 55m2 stops

$884Delta

Fri, Apr 10 - Sat, Apr 18

10:00 am - 7:05 am

STL

SCL

20h 05m1 stop

8:50 pm - 9:16 am

SCL

STL

13h 26m1 stop

$934American Airlines

Fri, Apr 10 - Sat, Apr 18

9:47 am - 7:40 am

STL

SCL

18h 53m1 stop

9:30 pm - 8:58 am

SCL

STL

14h 28m1 stop

$944LATAM Airlines

Sat, Dec 20 - Fri, Jan 2

12:00 pm - 6:10 am

STL

SCL

15h 10m1 stop

4:15 pm - 8:53 am

SCL

STL

19h 38m2 stops

$976LATAM Airlines

Tue, Jan 6 - Tue, Jan 13

LATAM Airlines flights from St. Louis to Santiago

Our best LATAM Airlines deals on St. Louis to Santiago flight tickets

LATAM Airlines

Mar 11

STL5:00 pmLambert-St Louis

19h 05m

2 stops

SCL2:05 pmSantiago Arturo Merino Benitez

Mar 23

SCL4:35 amSantiago Arturo Merino Benitez

21h 07m

2 stops

STL11:42 pmLambert-St Louis

$761

Find similar

LATAM Airlines

Jan 22

STL9:59 amLambert-St Louis

25h 31m

3 stops

SCL2:30 pmSantiago Arturo Merino Benitez

Jan 29

SCL4:15 pmSantiago Arturo Merino Benitez

19h 38m

2 stops

STL8:53 amLambert-St Louis

$769

Find similar

LATAM Airlines

Mar 9

STL3:58 pmLambert-St Louis

23h 57m

2 stops

SCL5:55 pmSantiago Arturo Merino Benitez

Mar 20

SCL10:25 pmSantiago Arturo Merino Benitez

27h 17m

2 stops

STL11:42 pmLambert-St Louis

$859

Find similar

American Airlines flights from St. Louis to Santiago

Our best American Airlines deals on St. Louis to Santiago flight tickets

American Airlines

Mar 20

STL11:22 amLambert-St Louis

19h 43m

1 stop

SCL9:05 amSantiago Arturo Merino Benitez

Mar 28

SCL9:15 pmSantiago Arturo Merino Benitez

15h 17m

1 stop

STL10:32 amLambert-St Louis

$894

Find similar

American Airlines

Apr 10

STL10:00 amLambert-St Louis

20h 05m

1 stop

SCL7:05 amSantiago Arturo Merino Benitez

Apr 18

SCL8:50 pmSantiago Arturo Merino Benitez

13h 26m

1 stop

STL9:16 amLambert-St Louis

$934

Find similar

American Airlines

Dec 24

STL6:00 pmLambert-St Louis

12h 25m

1 stop

SCL9:25 amSantiago Arturo Merino Benitez

Jan 6

SCL10:30 pmSantiago Arturo Merino Benitez

20h 44m

1 stop

STL4:14 pmLambert-St Louis

$1,502

Find similar

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

10:00 am-7:50 am

2 stops19h 50m

Santiago Arturo Merino Benitez

Mon 3/23

9:45 pm-9:21 am

1 stop13h 36m

$752

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

5:00 am-7:50 am

2 stops24h 50m

Santiago Arturo Merino Benitez

Mon 3/23

9:45 pm-9:21 am

1 stop13h 36m

$755

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

5:00 pm-2:05 pm

2 stops19h 05m

Santiago Arturo Merino Benitez

Mon 3/23

4:35 am-11:42 pm

2 stops21h 07m

$761

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

5:00 pm-2:05 pm

2 stops19h 05m

Santiago Arturo Merino Benitez

Mon 3/23

5:15 am-11:42 pm

2 stops20h 27m

$764

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Fri 3/20

10:02 am-6:35 am

2 stops18h 33m

Santiago Arturo Merino Benitez

Sun 3/29

12:25 am-9:10 pm

2 stops22h 45m

$804

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Mon 3/9

3:58 pm-5:55 pm

2 stops23h 57m

Santiago Arturo Merino Benitez

Fri 3/20

10:25 pm-11:42 pm

2 stops27h 17m

$859

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Fri 4/10

7:10 am-5:45 am

2 stops21h 35m

Santiago Arturo Merino Benitez

Sat 4/18

4:50 pm-10:45 am

2 stops18h 55m

$884

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Fri 4/10

10:00 am-7:05 am

1 stop20h 05m

Santiago Arturo Merino Benitez

Sat 4/18

8:50 pm-9:16 am

1 stop13h 26m

$934

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Sat 12/20

9:47 am-7:40 am

1 stop18h 53m

Santiago Arturo Merino Benitez

Fri 1/2

9:30 pm-8:58 am

1 stop14h 28m

$944

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Tue 1/6

12:00 pm-6:10 am

1 stop15h 10m

Santiago Arturo Merino Benitez

Tue 1/13

4:15 pm-8:53 am

2 stops19h 38m

$976

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 14 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the cheapest month to fly to Santiago?

In general, March is the cheapest month to fly from St. Louis to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $876. If you don’t want to visit Santiago in March, then you should wait until July to fly from St. Louis, when ticket prices are also cheap, with an average price of $883.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $955. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,189.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from St. Louis to Santiago when you can find flight prices for as low as $982. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,074 per ticket.

When to book flights from St. Louis to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to Santiago (STL to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santiago

Fastest flight time	12h 30m
Direct flights	None

The fastest flight from St. Louis to Santiago takes 12h 30m

There are no direct flights from St. Louis to Santiago. There are no popular flight routes from St. Louis to Santiago.

Search flight deals

How far is Lambert-St Louis to Santiago Arturo Merino Benitez by plane?
The distance between Lambert-St Louis and Santiago Arturo Merino Benitez is about 5131.6 mi. Typically, this will take 12h 25m by plane in normal conditions.
When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.
How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
As of December 2025, there are 4 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from St. Louis to Santiago?
Based on momondo bookings for flights between St. Louis and Santiago, the leading airline is Delta, making up 32% of the total bookings. Other popular airlines include LATAM Airlines with 31%, American Airlines with 27%, and United Airlines with 10%.

Best airlines flying from St. Louis to Santiago

Compare and see reviews for airlines that fly from St. Louis to Santiago with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $689	Free Cancellation	Rating 7.2 11,044 reviews	Search American Airlines flights
United Airlines	PriceFrom $764	Free Cancellation	Rating 7.4 9,078 reviews	Search United Airlines flights
Delta	PriceFrom $803	Free Cancellation	Rating 7.9 8,010 reviews	Search Delta flights
LATAM Airlines	PriceFrom $823	Free Cancellation	Rating 7.5 1,889 reviews	Search LATAM Airlines flights

Viña del Mar

Santa Cruz

Valparaíso

Valle Nevado

San Fernando

Pichilemu

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Why should I use momondo to find a flight deal from St. Louis to Santiago?

Finding the right flight to Santiago from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from St. Louis to Santiago with flexible booking policies on momondo?

Flights from St. Louis to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from St. Louis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from St. Louis to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.

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Cheap flights from St. Louis to Santiago from $356

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Santiago departing on 12/14. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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LATAM Airlines flights from St. Louis to Santiago

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How to get the cheapest flight ticket from St. Louis to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santiago?

What is the cheapest day to depart on your flight to Santiago?

What is the cheapest time of day to depart on your flight to Santiago?

What is the cheapest airline that flies from Lambert-St Louis to Santiago Arturo Merino Benitez?

LATAM Airlines and Air Canada are the most popular carriers operating from Lambert-St Louis to Santiago Arturo Merino Benitez

What airlines fly to Santiago?

When to book flights from St. Louis to Santiago

Cheap St. Louis to Santiago (STL to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santiago

Fastest flight time

Direct flights

How far is Lambert-St Louis to Santiago Arturo Merino Benitez by plane?

When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

What is the most popular airline from St. Louis to Santiago?

Best airlines flying from St. Louis to Santiago

Compare and see reviews for airlines that fly from St. Louis to Santiago with momondo

Traveling to a place near Santiago?

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santiago?

Can I find flights from St. Louis to Santiago with flexible booking policies on momondo?

How can momondo help me find flights from St. Louis to Santiago?

I’m not ready to book a flight from St. Louis to Santiago right now. Can momondo alert me if prices change?

An easier way to manage your Santiago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Chile

Airports servicing Chile