What airlines fly to Santiago?

LATAM Airlines, Delta and American Airlines are the top three most popular airlines that fly to Santiago from St. Louis according to our data. LATAM Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 4 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.

How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

As of November 2025, there are 4 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$328 Cheap Flights from St. Louis to Santiago in 2025/26

Q: What is the typical price of a round-trip flight between St. Louis and Santiago?

Prices are currently low for flights on this route. Typical prices usually range from $841 to $1,161. The lowest price recently found on this route was $735.

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Find the cheapest flights from St. Louis to Santiago

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One-way

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Cheap round-trip flights

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6:00 am - 5:35 amSTL-SCL

20h 35m2 stops

11:25 pm - 7:14 pmSCL-STL

21h 49m2 stops

$735LATAM Airlines

Find Deal

Thu, Mar 5 - Mon, Mar 16

10:13 am - 5:35 amSTL-SCL

16h 22m2 stops

11:15 pm - 11:50 amSCL-STL

14h 35m1 stop

$737LATAM Airlines

Find Deal

Thu, Mar 5 - Mon, Mar 16

11:55 am - 7:00 amSTL-SCL

16h 05m2 stops

11:25 pm - 3:01 pmSCL-STL

17h 36m2 stops

$740LATAM Airlines

Find Deal

Wed, Mar 4 - Wed, Mar 18

11:55 am - 7:00 amSTL-SCL

16h 05m2 stops

11:15 pm - 10:50 amSCL-STL

13h 35m1 stop

$745LATAM Airlines

Find Deal

Wed, Mar 4 - Wed, Mar 18

1:00 pm - 7:00 amSTL-SCL

16h 00m2 stops

11:25 pm - 7:14 pmSCL-STL

21h 49m2 stops

$746LATAM Airlines

Find Deal

Wed, Mar 11 - Mon, Mar 23

6:00 am - 5:35 amSTL-SCL

21h 35m2 stops

11:25 pm - 7:14 pmSCL-STL

21h 49m2 stops

$748LATAM Airlines

Find Deal

Wed, Mar 11 - Mon, Mar 23

6:00 am - 5:35 amSTL-SCL

21h 35m2 stops

11:25 pm - 7:14 pmSCL-STL

21h 49m2 stops

$749LATAM Airlines

Find Deal

Wed, Mar 11 - Mon, Mar 23

1:00 pm - 7:00 amSTL-SCL

16h 00m2 stops

11:15 pm - 7:14 pmSCL-STL

21h 59m1 stop

$750LATAM Airlines

Find Deal

Wed, Mar 11 - Mon, Mar 23

1:00 pm - 7:00 amSTL-SCL

16h 00m2 stops

11:15 pm - 11:50 amSCL-STL

14h 35m1 stop

$752LATAM Airlines

Find Deal

Wed, Mar 11 - Mon, Mar 23

10:00 am - 5:35 amSTL-SCL

17h 35m2 stops

11:15 pm - 11:50 amSCL-STL

14h 35m1 stop

$753LATAM Airlines

Find Deal

Wed, Mar 11 - Mon, Mar 23

United Airlines flights from St. Louis to Santiago

Our best United Airlines deals on St. Louis to Santiago flight tickets

United Airlines

Mar 11

STL10:05 amLambert-St Louis

19h 45m

1 stop

SCL7:50 amSantiago Arturo Merino Benitez

Mar 23

SCL9:45 pmSantiago Arturo Merino Benitez

13h 36m

1 stop

STL9:21 amLambert-St Louis

$755

Find similar

United Airlines

Mar 11

STL6:00 amLambert-St Louis

23h 50m

1 stop

SCL7:50 amSantiago Arturo Merino Benitez

Mar 23

SCL9:45 pmSantiago Arturo Merino Benitez

13h 36m

1 stop

STL9:21 amLambert-St Louis

$756

Find similar

United Airlines

Feb 15

STL9:55 amLambert-St Louis

43h 55m

2 stops

SCL8:50 amSantiago Arturo Merino Benitez

Feb 27

SCL10:45 pmSantiago Arturo Merino Benitez

13h 38m

1 stop

STL9:23 amLambert-St Louis

$824

Find similar

Delta flights from St. Louis to Santiago

Our best Delta deals on St. Louis to Santiago flight tickets

Delta

Mar 12

STL10:00 amLambert-St Louis

18h 35m

2 stops

SCL6:35 amSantiago Arturo Merino Benitez

Mar 24

SCL6:30 pmSantiago Arturo Merino Benitez

19h 20m

2 stops

STL11:50 amLambert-St Louis

$764

Find similar

Delta

Nov 27

STL11:04 amLambert-St Louis

16h 56m

2 stops

SCL7:00 amSantiago Arturo Merino Benitez

Dec 8

SCL8:15 amSantiago Arturo Merino Benitez

18h 27m

2 stops

STL11:42 pmLambert-St Louis

$769

Find similar

Delta

Dec 6

STL5:12 pmLambert-St Louis

17h 53m

2 stops

SCL2:05 pmSantiago Arturo Merino Benitez

Dec 9

SCL4:35 amSantiago Arturo Merino Benitez

20h 22m

2 stops

STL9:57 pmLambert-St Louis

$804

Find similar

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 3/5

6:00 am-5:35 am

2 stops20h 35m

Santiago Arturo Merino Benitez

Mon 3/16

11:25 pm-7:14 pm

2 stops21h 49m

$735

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Thu 3/5

10:13 am-5:35 am

2 stops16h 22m

Santiago Arturo Merino Benitez

Mon 3/16

11:15 pm-11:50 am

1 stop14h 35m

$737

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/4

11:55 am-7:00 am

2 stops16h 05m

Santiago Arturo Merino Benitez

Wed 3/18

11:25 pm-3:01 pm

2 stops17h 36m

$740

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/4

11:55 am-7:00 am

2 stops16h 05m

Santiago Arturo Merino Benitez

Wed 3/18

11:15 pm-10:50 am

1 stop13h 35m

$745

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

1:00 pm-7:00 am

2 stops16h 00m

Santiago Arturo Merino Benitez

Mon 3/23

11:25 pm-7:14 pm

2 stops21h 49m

$746

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

6:00 am-5:35 am

2 stops21h 35m

Santiago Arturo Merino Benitez

Mon 3/23

11:25 pm-7:14 pm

2 stops21h 49m

$748

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

6:00 am-5:35 am

2 stops21h 35m

Santiago Arturo Merino Benitez

Mon 3/23

11:25 pm-7:14 pm

2 stops21h 49m

$749

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

1:00 pm-7:00 am

2 stops16h 00m

Santiago Arturo Merino Benitez

Mon 3/23

11:15 pm-7:14 pm

1 stop21h 59m

$750

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

1:00 pm-7:00 am

2 stops16h 00m

Santiago Arturo Merino Benitez

Mon 3/23

11:15 pm-11:50 am

1 stop14h 35m

$752

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

10:00 am-5:35 am

2 stops17h 35m

Santiago Arturo Merino Benitez

Mon 3/23

11:15 pm-11:50 am

1 stop14h 35m

$753

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between St. Louis and Santiago?

What is the cheapest month to fly to Santiago?

In general, March is the cheapest month to fly from St. Louis to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $883. If you don’t want to visit Santiago in March, then you should wait until July to fly from St. Louis, when ticket prices are also cheap, with an average price of $883.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $955. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,189.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from St. Louis to Santiago when you can find flight prices for as low as $982. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,074 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $991 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from St. Louis for as low as $740 on momondo.

When to book flights from St. Louis to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to Santiago (STL to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santiago

Direct flights	None

There are no direct flights from St. Louis to Santiago. There are no popular flight routes from St. Louis to Santiago.

Search flight deals

How far is Lambert-St Louis to Santiago Arturo Merino Benitez by plane?
The distance between Lambert-St Louis and Santiago Arturo Merino Benitez is about 5131.6 mi. Typically, this will take 12h 00m by plane in normal conditions.
When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.
How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
As of November 2025, there are 4 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from St. Louis to Santiago?
Based on momondo bookings for flights between St. Louis and Santiago, the leading airline is LATAM Airlines, making up 40% of the total bookings. Other popular airlines include Delta with 29%, American Airlines with 22%, and United Airlines with 9%.

Best airlines flying from St. Louis to Santiago

Compare and see reviews for airlines that fly from St. Louis to Santiago with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $689	Free Cancellation	Rating 7.2 11,045 reviews	Search American Airlines flights
United Airlines	PriceFrom $764	Free Cancellation	Rating 7.4 9,027 reviews	Search United Airlines flights
LATAM Airlines	PriceFrom $773	Free Cancellation	Rating 7.5 1,882 reviews	Search LATAM Airlines flights
Delta	PriceFrom $803	Free Cancellation	Rating 7.9 8,002 reviews	Search Delta flights

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Valparaíso

Valle Nevado

San Fernando

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Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santiago?

Finding the right flight to Santiago from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from St. Louis to Santiago with flexible booking policies on momondo?

Flights from St. Louis to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from St. Louis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from St. Louis to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.