What is the cheapest airline that flies from Lambert-St Louis to Santiago Arturo Merino Benitez?

LATAM Airlines and Delta are the most popular carriers operating from Lambert-St Louis to Santiago Arturo Merino Benitez

Which layover airport offers the lowest fares from St. Louis to Santiago?

Flights via Miami (MIA) offer the lowest average round-trip price of $898.

Which layover airport has the shortest travel time from St. Louis to Santiago?

Flights connecting via Miami (MIA) have the shortest average one-way travel time: 12h 45m.

Which airport is the most popular layover for flights between St. Louis and Santiago?

Atlanta (ATL) was the most common stop: 67% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport has the shortest connection time from St. Louis to Santiago?

Atlanta (ATL) has the shortest average layover time for this route: 2h 05m.

What airlines fly to Santiago?

Delta, American Airlines and LATAM Airlines are the top three most popular airlines that fly to Santiago from St. Louis according to our data. Delta is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 3 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.

How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

As of November 2026, there are 3 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$359 Cheap Flights from St. Louis to Santiago in 2026/27

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from St. Louis to Santiago

Round-trip

One-way

Last minute

Cheap round-trip flights

Enter your travel dates to find the best prices.

1:20 pm - 3:10 pmSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

22h 50m2 stops Orlando Bogotá El Dorado

4:15 pm - 12:12 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

34h 57m2 stops Bogotá El Dorado Orlando

$718Multiple Airlines

Fri, Nov 27 - Fri, Dec 4

3:04 pm - 5:45 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

35h 41m3 stops Denver Intl Orlando Bogotá El Dorado

4:15 pm - 12:12 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

34h 57m2 stops Bogotá El Dorado Orlando

$771Multiple Airlines

Mon, Nov 23 - Thu, Dec 3

9:52 am - 3:00 pmSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

26h 08m3 stops Atlanta Hartsfield-Jackson Miami Buenos Aires Ministro Pistarini

8:25 pm - 9:07 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

15h 42m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

$962LATAM Airlines

Wed, Dec 23 - Mon, Dec 28

6:00 am - 5:55 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

20h 55m2 stops Atlanta Hartsfield-Jackson Miami

11:00 pm - 11:52 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

15h 52m1 stop Atlanta Hartsfield-Jackson

$962LATAM Airlines

Wed, Dec 23 - Mon, Dec 28

6:00 am - 5:55 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

20h 55m2 stops Atlanta Hartsfield-Jackson Miami

5:55 pm - 9:07 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

18h 12m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

$962LATAM Airlines

Wed, Dec 23 - Mon, Dec 28

1:20 pm - 5:45 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

37h 25m2 stops Orlando Bogotá El Dorado

2:10 am - 12:12 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

25h 02m2 stops Bogotá El Dorado Orlando

$1,099Multiple Airlines

Mon, Nov 23 - Wed, Dec 2

6:49 pm - 2:55 pmSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

17h 06m2 stops Atlanta Hartsfield-Jackson Sao Paulo Guarulhos Intl

11:10 pm - 9:09 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

12h 59m1 stop Atlanta Hartsfield-Jackson

$1,116Delta

Mon, Feb 15 - Tue, Mar 2

4:50 pm - 3:00 pmSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

19h 10m2 stops Atlanta Hartsfield-Jackson Lima J Chavez Intl

8:13 am - 11:39 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

18h 26m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$1,116Delta

Mon, Feb 15 - Tue, Mar 2

10:00 am - 7:05 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

20h 05m1 stop Miami

8:35 pm - 9:20 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

13h 45m1 stop Miami

$1,116American Airlines

Fri, Apr 9 - Fri, Apr 16

12:27 pm - 7:05 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

17h 38m2 stops Chicago O'Hare Intl Miami

8:35 pm - 9:20 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

13h 45m1 stop Miami

$1,120American Airlines

Fri, Apr 9 - Fri, Apr 16

Cheap last minute flights

Enter your travel dates to find the best prices.

6:00 am - 7:30 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

22h 30m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

4:35 pm - 4:23 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

26h 48m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$1,138LATAM Airlines

Sun, Nov 8 - Thu, Nov 12

12:00 pm - 7:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

16h 40m1 stop Atlanta Hartsfield-Jackson

4:35 pm - 11:56 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

34h 21m2 stops Bogotá El Dorado Atlanta Hartsfield-Jackson

$1,138LATAM Airlines

Sun, Nov 8 - Thu, Nov 12

10:47 am - 7:30 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

17h 43m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

11:10 pm - 4:43 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

20h 33m1 stop Atlanta Hartsfield-Jackson

$1,163Delta

Sat, Nov 7 - Mon, Nov 9

6:00 am - 7:40 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

22h 40m1 stop Atlanta Hartsfield-Jackson

11:10 pm - 11:15 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

15h 05m1 stop Atlanta Hartsfield-Jackson

$1,163Delta

Sun, Nov 8 - Thu, Nov 12

2:55 pm - 8:50 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

14h 55m1 stop Houston George Bush Intcntl

10:45 pm - 6:38 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

22h 53m1 stop Houston George Bush Intcntl

$1,163United Airlines

Sat, Nov 7 - Mon, Nov 9

6:00 am - 7:30 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

22h 30m2 stops Atlanta Hartsfield-Jackson Bogotá El Dorado

8:25 pm - 9:00 amSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

15h 35m2 stops Lima J Chavez Intl Atlanta Hartsfield-Jackson

$1,163Delta

Sat, Nov 7 - Mon, Nov 9

7:30 am - 8:50 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

22h 20m2 stops Chicago O'Hare Intl Houston George Bush Intcntl

10:45 pm - 2:34 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

18h 49m2 stops Houston George Bush Intcntl Chicago O'Hare Intl

$1,167United Airlines

Sun, Nov 8 - Thu, Nov 12

4:26 pm - 5:45 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

34h 19m3 stops Orlando Dallas/Fort Worth Bogotá El Dorado

9:55 pm - 7:23 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

24h 28m2 stops Toronto Pearson Intl Chicago O'Hare Intl

$2,114Multiple Airlines

Sat, Nov 7 - Mon, Nov 9

4:26 pm - 5:45 amSTL Lambert-St Louis-SCL Santiago Arturo Merino Benitez

34h 19m3 stops Orlando Dallas/Fort Worth Bogotá El Dorado

8:30 am - 3:23 pmSCL Santiago Arturo Merino Benitez-STL Lambert-St Louis

33h 53m3 stops Rio de Janeiro–Galeão Intl Sao Paulo Guarulhos Intl Toronto Pearson Intl

$2,617Multiple Airlines

Sat, Nov 7 - Mon, Nov 9

Save money when you book flights with momondo

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Not ready to book? to track prices.

Search flight deals

United Airlines flights from St. Louis to Santiago

Our best United Airlines deals on St. Louis to Santiago flight tickets

United Airlines

Dec 25

STL6:15 amLambert-St Louis

23h 35m

1 stop

SCL8:50 amSantiago Arturo Merino Benitez

Jan 21

SCL10:45 pmSantiago Arturo Merino Benitez

18h 21m

1 stop

STL2:06 pmLambert-St Louis

$1,127

United Airlines

Dec 25

STL6:15 amLambert-St Louis

23h 35m

1 stop

SCL8:50 amSantiago Arturo Merino Benitez

Jan 19

SCL10:45 pmSantiago Arturo Merino Benitez

21h 28m

2 stops

STL5:13 pmLambert-St Louis

$1,131

United Airlines

Nov 7

STL2:55 pmLambert-St Louis

14h 55m

1 stop

SCL8:50 amSantiago Arturo Merino Benitez

Nov 9

SCL10:45 pmSantiago Arturo Merino Benitez

22h 53m

1 stop

STL6:38 pmLambert-St Louis

$1,163

Delta flights from St. Louis to Santiago

Our best Delta deals on St. Louis to Santiago flight tickets

Delta

Feb 15

STL4:50 pmLambert-St Louis

19h 10m

2 stops

SCL3:00 pmSantiago Arturo Merino Benitez

Mar 2

SCL8:13 amSantiago Arturo Merino Benitez

18h 26m

2 stops

STL11:39 pmLambert-St Louis

$1,116

Delta

Dec 26

STL7:15 pmLambert-St Louis

32h 25m

1 stop

SCL6:40 amSantiago Arturo Merino Benitez

Jan 19

SCL12:48 amSantiago Arturo Merino Benitez

23h 57m

2 stops

STL9:45 pmLambert-St Louis

$1,135

Delta

Nov 27

STL3:15 pmLambert-St Louis

20h 45m

2 stops

SCL3:00 pmSantiago Arturo Merino Benitez

Dec 4

SCL11:10 pmSantiago Arturo Merino Benitez

13h 39m

1 stop

STL9:49 amLambert-St Louis

$1,138

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Fri 11/27

1:20 pm-3:10 pm

2 stops22h 50m

Santiago Arturo Merino Benitez

Fri 12/4

4:15 pm-12:12 am

2 stops34h 57m

$718

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Mon 11/23

3:04 pm-5:45 am

3 stops35h 41m

Santiago Arturo Merino Benitez

Thu 12/3

4:15 pm-12:12 am

2 stops34h 57m

$771

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Wed 12/23

9:52 am-3:00 pm

3 stops26h 08m

Santiago Arturo Merino Benitez

Mon 12/28

8:25 pm-9:07 am

2 stops15h 42m

$962

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Wed 12/23

6:00 am-5:55 am

2 stops20h 55m

Santiago Arturo Merino Benitez

Mon 12/28

11:00 pm-11:52 am

1 stop15h 52m

$962

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Wed 12/23

6:00 am-5:55 am

2 stops20h 55m

Santiago Arturo Merino Benitez

Mon 12/28

5:55 pm-9:07 am

2 stops18h 12m

$962

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Mon 11/23

1:20 pm-5:45 am

2 stops37h 25m

Santiago Arturo Merino Benitez

Wed 12/2

2:10 am-12:12 am

2 stops25h 02m

$1,099

Quickest round-trip

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Mon 2/15

6:49 pm-2:55 pm

2 stops17h 06m

Santiago Arturo Merino Benitez

Tue 3/2

11:10 pm-9:09 am

1 stop12h 59m

$1,116

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Mon 2/15

4:50 pm-3:00 pm

2 stops19h 10m

Santiago Arturo Merino Benitez

Tue 3/2

8:13 am-11:39 pm

2 stops18h 26m

$1,116

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Fri 4/9

10:00 am-7:05 am

1 stop20h 05m

Santiago Arturo Merino Benitez

Fri 4/16

8:35 pm-9:20 am

1 stop13h 45m

$1,116

St. LouisSantiago

STL Lambert-St Louis - SCL Santiago Arturo Merino Benitez

STLSCL

Lambert-St Louis

Fri 4/9

12:27 pm-7:05 am

2 stops17h 38m

Santiago Arturo Merino Benitez

Fri 4/16

8:35 pm-9:20 am

1 stop13h 45m

$1,120

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Layovers

What is the typical price of a round-trip flight between St. Louis and Santiago?

Prices are currently low for flights on this route.

Typical prices usually range from $1,258 to $1,405.
The lowest price recently found on this route was $718.

What is the cheapest month to fly to Santiago?

In general, October is the cheapest month to fly from St. Louis to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $995. If you don’t want to visit Santiago in October, then you should wait until March to fly from St. Louis, when ticket prices are also cheap, with an average price of $1,003.

When to book flights from St. Louis to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to Santiago (STL to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santiago

Best Price Found	$359
Fastest flight time	14h 50m
Direct flights	None

The best one-way flight to Santiago from St. Louis in the past 72 hours is $359. The best round-trip flight deal from St. Louis to Santiago found on momondo in the last 72 hours is $718.

The fastest flight from St. Louis to Santiago takes 14h 50m

There are no direct flights from St. Louis to Santiago. There are no popular flight routes from St. Louis to Santiago.

Search flight deals

Frequently asked questions about flying from St. Louis to Santiago

How far is Lambert-St Louis to Santiago Arturo Merino Benitez by plane?
The distance between Lambert-St Louis and Santiago Arturo Merino Benitez is about 5131.6 mi. Typically, this will take 14h 50m by plane in normal conditions.
When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.
How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
As of November 2026, there are 3 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from St. Louis to Santiago?
Based on momondo bookings for flights between St. Louis and Santiago, the leading airline is Delta, making up 52% of the total bookings. Other popular airlines include American Airlines with 24% and LATAM Airlines with 24%.

Best airlines flying from St. Louis to Santiago

Compare and see reviews for airlines that fly from St. Louis to Santiago with momondo

Airline	Rating	Free Cancellation	Price
LATAM Airlines	PriceFrom $792	Free Cancellation	Rating 7.4 1,968 reviews	Search LATAM Airlines flights
Delta	PriceFrom $858	Free Cancellation	Rating 7.8 8,696 reviews	Search Delta flights
American Airlines	PriceFrom $894	Free Cancellation	Rating 7.0 12,230 reviews	Search American Airlines flights

Viña del Mar

Valparaíso

Santa Cruz

San Fernando

Valle Nevado

Pichilemu

Zapallar

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santiago?

Finding the right flight to Santiago from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from St. Louis to Santiago with flexible booking policies on momondo?

Flights from St. Louis to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from St. Louis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from St. Louis to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.