What is the cheapest airline that flies from Lambert-St Louis to Santiago Arturo Merino Benitez?

Delta is the most popular carrier operating from Lambert-St Louis to Santiago Arturo Merino Benitez

What airlines fly to Santiago?

LATAM Airlines, Delta and American Airlines are the top three most popular airlines that fly to Santiago from St. Louis according to our data. LATAM Airlines is the first choice among our users, with 32% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 4 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.

How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

As of November 2025, there are 4 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$349 Cheap Flights from St. Louis to Santiago in 2025/26

Q: What is the typical price of a round-trip flight between St. Louis and Santiago?

Prices are currently low for flights on this route. Typical prices usually range from $839 to $1,340. The lowest price recently found on this route was $740.

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Find the cheapest flights from St. Louis to Santiago

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Cheap round-trip flights

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6:00 am - 5:35 amSTL-SCL

20h 35m2 stops

11:25 pm - 4:07 pmSCL-STL

19h 42m2 stops

$740LATAM Airlines

Find Deal

Mon, Dec 8 - Mon, Feb 2

10:05 am - 7:50 amSTL-SCL

19h 45m1 stop

9:45 pm - 9:21 amSCL-STL

13h 36m1 stop

$750United Airlines

Find Deal

Wed, Mar 11 - Mon, Mar 23

10:02 am - 5:35 amSTL-SCL

17h 33m2 stops

10:10 pm - 8:52 amSCL-STL

12h 42m1 stop

$754LATAM Airlines

Find Deal

Wed, Mar 11 - Mon, Mar 23

6:00 am - 7:50 amSTL-SCL

23h 50m1 stop

9:45 pm - 9:21 amSCL-STL

13h 36m1 stop

$756United Airlines

Find Deal

Wed, Mar 11 - Mon, Mar 23

10:00 am - 7:50 amSTL-SCL

19h 50m2 stops

9:45 pm - 9:50 pmSCL-STL

26h 05m2 stops

$757United Airlines

Find Deal

Wed, Mar 11 - Mon, Mar 23

7:10 am - 7:40 amSTL-SCL

22h 30m1 stop

10:10 pm - 8:52 amSCL-STL

12h 42m1 stop

$764Delta

Find Deal

Mon, Mar 9 - Thu, Mar 26

9:30 am - 6:25 amSTL-SCL

17h 55m2 stops

4:35 am - 11:37 pmSCL-STL

22h 02m2 stops

$766LATAM Airlines

Find Deal

Mon, Dec 8 - Sun, Feb 1

10:00 am - 7:50 amSTL-SCL

19h 50m2 stops

9:45 pm - 9:00 pmSCL-STL

25h 15m2 stops

$769United Airlines

Find Deal

Wed, Mar 11 - Tue, Mar 24

1:57 pm - 2:30 pmSTL-SCL

21h 33m3 stops

4:35 am - 11:37 pmSCL-STL

22h 02m2 stops

$770LATAM Airlines

Find Deal

Mon, Dec 8 - Sun, Feb 1

6:59 pm - 7:40 amSTL-SCL

34h 41m1 stop

8:50 am - 11:42 pmSCL-STL

16h 52m2 stops

$772Delta

Find Deal

Sun, Mar 8 - Tue, Mar 24

LATAM Airlines flights from St. Louis to Santiago

Our best LATAM Airlines deals on St. Louis to Santiago flight tickets

LATAM Airlines

Dec 8

STL6:00 amLambert-St Louis

20h 35m

2 stops

SCL5:35 amSantiago Arturo Merino Benitez

Feb 2

SCL11:25 pmSantiago Arturo Merino Benitez

19h 42m

2 stops

STL4:07 pmLambert-St Louis

$740

Find similar

LATAM Airlines

Mar 11

STL10:02 amLambert-St Louis

17h 33m

2 stops

SCL5:35 amSantiago Arturo Merino Benitez

Mar 23

SCL10:10 pmSantiago Arturo Merino Benitez

12h 42m

1 stop

STL8:52 amLambert-St Louis

$754

Find similar

LATAM Airlines

Dec 8

STL9:30 amLambert-St Louis

17h 55m

2 stops

SCL6:25 amSantiago Arturo Merino Benitez

Feb 1

SCL4:35 amSantiago Arturo Merino Benitez

22h 02m

2 stops

STL11:37 pmLambert-St Louis

$766

Find similar

Delta flights from St. Louis to Santiago

Our best Delta deals on St. Louis to Santiago flight tickets

Delta

Mar 9

STL7:10 amLambert-St Louis

22h 30m

1 stop

SCL7:40 amSantiago Arturo Merino Benitez

Mar 26

SCL10:10 pmSantiago Arturo Merino Benitez

12h 42m

1 stop

STL8:52 amLambert-St Louis

$764

Find similar

Delta

Mar 8

STL6:59 pmLambert-St Louis

34h 41m

1 stop

SCL7:40 amSantiago Arturo Merino Benitez

Mar 24

SCL8:50 amSantiago Arturo Merino Benitez

16h 52m

2 stops

STL11:42 pmLambert-St Louis

$772

Find similar

Delta

Dec 6

STL11:19 amLambert-St Louis

16h 16m

2 stops

SCL6:35 amSantiago Arturo Merino Benitez

Dec 10

SCL8:15 amSantiago Arturo Merino Benitez

16h 42m

2 stops

STL9:57 pmLambert-St Louis

$804

Find similar

Fly from

Fly to

Route

Depart

Return

Price

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Mon 12/8

6:00 am-5:35 am

2 stops20h 35m

Santiago Arturo Merino Benitez

Mon 2/2

11:25 pm-4:07 pm

2 stops19h 42m

$740

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

10:05 am-7:50 am

1 stop19h 45m

Santiago Arturo Merino Benitez

Mon 3/23

9:45 pm-9:21 am

1 stop13h 36m

$750

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

10:02 am-5:35 am

2 stops17h 33m

Santiago Arturo Merino Benitez

Mon 3/23

10:10 pm-8:52 am

1 stop12h 42m

$754

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

6:00 am-7:50 am

1 stop23h 50m

Santiago Arturo Merino Benitez

Mon 3/23

9:45 pm-9:21 am

1 stop13h 36m

$756

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

10:00 am-7:50 am

2 stops19h 50m

Santiago Arturo Merino Benitez

Mon 3/23

9:45 pm-9:50 pm

2 stops26h 05m

$757

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Mon 3/9

7:10 am-7:40 am

1 stop22h 30m

Santiago Arturo Merino Benitez

Thu 3/26

10:10 pm-8:52 am

1 stop12h 42m

$764

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Mon 12/8

9:30 am-6:25 am

2 stops17h 55m

Santiago Arturo Merino Benitez

Sun 2/1

4:35 am-11:37 pm

2 stops22h 02m

$766

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Wed 3/11

10:00 am-7:50 am

2 stops19h 50m

Santiago Arturo Merino Benitez

Tue 3/24

9:45 pm-9:00 pm

2 stops25h 15m

$769

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Mon 12/8

1:57 pm-2:30 pm

3 stops21h 33m

Santiago Arturo Merino Benitez

Sun 2/1

4:35 am-11:37 pm

2 stops22h 02m

$770

St. LouisSantiago

STL - SCL

STLSCL

Lambert-St Louis

Sun 3/8

6:59 pm-7:40 am

1 stop34h 41m

Santiago Arturo Merino Benitez

Tue 3/24

8:50 am-11:42 pm

2 stops16h 52m

$772

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 13 resultsSorted by cheapest first

How to get the cheapest flight ticket from St. Louis to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

What is the typical price of a round-trip flight between St. Louis and Santiago?

What is the cheapest month to fly to Santiago?

In general, March is the cheapest month to fly from St. Louis to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $883. If you don’t want to visit Santiago in March, then you should wait until July to fly from St. Louis, when ticket prices are also cheap, with an average price of $883.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Wednesday when prices can be found for as low as $955. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,189.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from St. Louis to Santiago when you can find flight prices for as low as $982. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,074 per ticket.

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from St. Louis when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $991 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from St. Louis for as low as $740 on momondo.

When to book flights from St. Louis to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from St. Louis to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap St. Louis to Santiago (STL to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santiago

Fastest flight time	15h 31m
Direct flights	None

The fastest flight from St. Louis to Santiago takes 15h 31m

There are no direct flights from St. Louis to Santiago. There are no popular flight routes from St. Louis to Santiago.

Search flight deals

How far is Lambert-St Louis to Santiago Arturo Merino Benitez by plane?
The distance between Lambert-St Louis and Santiago Arturo Merino Benitez is about 5131.6 mi. Typically, this will take 12h 40m by plane in normal conditions.
When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport are updated daily.
How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
As of November 2025, there are 4 operators available to choose from for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from St. Louis to Santiago?
Based on momondo bookings for flights between St. Louis and Santiago, the leading airline is LATAM Airlines, making up 32% of the total bookings. Other popular airlines include Delta with 31%, American Airlines with 27%, and United Airlines with 10%.

Best airlines flying from St. Louis to Santiago

Compare and see reviews for airlines that fly from St. Louis to Santiago with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $689	Free Cancellation	Rating 7.2 11,038 reviews	Search American Airlines flights
United Airlines	PriceFrom $764	Free Cancellation	Rating 7.4 9,046 reviews	Search United Airlines flights
Delta	PriceFrom $803	Free Cancellation	Rating 7.9 7,998 reviews	Search Delta flights
LATAM Airlines	PriceFrom $822	Free Cancellation	Rating 7.5 1,886 reviews	Search LATAM Airlines flights

Viña del Mar

Santa Cruz

Valparaíso

Valle Nevado

San Fernando

Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santiago?

Finding the right flight to Santiago from St. Louis is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Santiago quick and easy, saving you time and money.

Can I find flights from St. Louis to Santiago with flexible booking policies on momondo?

Flights from St. Louis to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from St. Louis to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from St. Louis. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from St. Louis to Santiago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from St. Louis to Santiago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Santiago and let you know when they change.

An easier way to manage your Santiago trip

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Cheap flights from St. Louis to Santiago from $349

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from St. Louis to Santiago departing on 12/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Filter for what you want

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Cheap round-trip flights

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LATAM Airlines flights from St. Louis to Santiago

Our best LATAM Airlines deals on St. Louis to Santiago flight tickets

Delta flights from St. Louis to Santiago

Our best Delta deals on St. Louis to Santiago flight tickets

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How to get the cheapest flight ticket from St. Louis to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between St. Louis and Santiago?

What is the cheapest month to fly to Santiago?

What is the cheapest day to depart on your flight to Santiago?

What is the cheapest time of day to depart on your flight to Santiago?

How far in advance should I book a flight to Santiago?

What is the cheapest airline that flies from Lambert-St Louis to Santiago Arturo Merino Benitez?

Delta is the most popular carrier operating from Lambert-St Louis to Santiago Arturo Merino Benitez

What airlines fly to Santiago?

When to book flights from St. Louis to Santiago

Cheap St. Louis to Santiago (STL to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from St. Louis to Santiago

Fastest flight time

Direct flights

How far is Lambert-St Louis to Santiago Arturo Merino Benitez by plane?

When did momondo last update prices for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

How many operators does momondo search for flights from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

How old do you have to be to fly from Lambert-St Louis Airport to Santiago Arturo Merino Benitez Airport?

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

What is the most popular airline from St. Louis to Santiago?

Best airlines flying from St. Louis to Santiago

Compare and see reviews for airlines that fly from St. Louis to Santiago with momondo

Traveling to a place near Santiago?

Why use momondo?

Why should I use momondo to find a flight deal from St. Louis to Santiago?

Can I find flights from St. Louis to Santiago with flexible booking policies on momondo?

How can momondo help me find flights from St. Louis to Santiago?

I’m not ready to book a flight from St. Louis to Santiago right now. Can momondo alert me if prices change?

An easier way to manage your Santiago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Chile

Airports servicing Chile