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Cheap flights from Santo Domingo to Chicago from $160

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santo Domingo to Chicago departing on 1/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
3:59 am - 6:39 pmSDQ-ORD
16h 40m1 stop
Spirit Airlines Logo
5:05 am - 5:50 pmORD-SDQ
10h 45m1 stop
$271Spirit Airlines
Find Deal
Wed, Dec 24 - Sat, Jan 24
Spirit Airlines Logo
4:21 pm - 12:09 amSDQ-ORD
9h 48m1 stop
Spirit Airlines Logo
5:00 am - 3:23 pmORD-SDQ
8h 23m1 stop
$290Spirit Airlines
Find Deal
Thu, Dec 4 - Sun, Dec 7
Spirit Airlines Logo
4:25 pm - 9:47 amSDQ-ORD
19h 22m1 stop
Spirit Airlines Logo
5:05 am - 5:50 pmORD-SDQ
10h 45m1 stop
$303Spirit Airlines
Find Deal
Mon, Nov 17 - Wed, Jan 21
Spirit Airlines Logo
4:21 pm - 11:13 amSDQ-ORD
20h 52m1 stop
Spirit Airlines Logo
5:00 am - 3:23 pmORD-SDQ
8h 23m1 stop
$307Spirit Airlines
Find Deal
Thu, Dec 4 - Thu, Dec 11
Multiple Airlines Logo
4:35 pm - 4:25 pmSDQ-ORD
25h 50m1 stop
Multiple Airlines Logo
3:26 pm - 3:23 pmORD-SDQ
21h 57m1 stop
$325Multiple Airlines
Find Deal
Wed, Nov 26 - Sat, Dec 6
Multiple Airlines Logo
4:35 pm - 4:25 pmSDQ-ORD
25h 50m1 stop
Multiple Airlines Logo
3:20 pm - 3:23 pmORD-SDQ
22h 03m1 stop
$331Multiple Airlines
Find Deal
Wed, Nov 26 - Sun, Dec 7
JetBlue Logo
3:18 pm - 10:04 pmSDQ-ORD
8h 46m1 stop
JetBlue Logo
7:41 pm - 10:04 amORD-SDQ
12h 23m1 stop
$406JetBlue
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Sat, Dec 20 - Sun, Jan 4
American Airlines Logo
6:14 pm - 12:04 pmSDQ-ORD
19h 50m1 stop
American Airlines Logo
7:17 pm - 12:15 pmORD-SDQ
14h 58m1 stop
$424American Airlines
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Tue, Nov 18 - Sun, Nov 30
American Airlines Logo
1:28 pm - 10:54 pmSDQ-ORD
11h 26m2 stops
American Airlines Logo
2:40 pm - 11:50 pmORD-SDQ
7h 10m1 stop
$426American Airlines
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Thu, Dec 4 - Sun, Dec 7
Copa Airlines Logo
2:14 pm - 12:05 amSDQ-ORD
11h 51m1 stop
Copa Airlines Logo
2:13 pm - 2:17 amORD-SDQ
10h 04m1 stop
$431Copa Airlines
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Sat, Dec 27 - Sat, Jan 3

JetBlue flights from Santo Domingo to Chicago O'Hare Intl Airport

Our best JetBlue deals on Santo Domingo to Chicago O'Hare Intl Airport flight tickets
JetBlue
Dec 20
SDQ3:18 pmSanto Domingo Las Americas
8h 46m
1 stop
ORD10:04 pmChicago O'Hare Intl
Jan 4
ORD7:41 pmChicago O'Hare Intl
12h 23m
1 stop
SDQ10:04 amSanto Domingo Las Americas
$406
Find similar
JetBlue
Nov 7
SDQ4:10 amSanto Domingo Las Americas
18h 42m
1 stop
ORD8:52 pmChicago O'Hare Intl
Nov 11
ORD6:45 amChicago O'Hare Intl
16h 04m
1 stop
SDQ12:49 amSanto Domingo Las Americas
$539
Find similar
JetBlue
Nov 7
SDQ4:10 amSanto Domingo Las Americas
18h 42m
1 stop
ORD8:52 pmChicago O'Hare Intl
Nov 12
ORD6:45 amChicago O'Hare Intl
17h 08m
1 stop
SDQ1:53 amSanto Domingo Las Americas
$542
Find similar

American Airlines flights from Santo Domingo to Chicago O'Hare Intl Airport

Our best American Airlines deals on Santo Domingo to Chicago O'Hare Intl Airport flight tickets
American Airlines
Nov 18
SDQ6:14 pmSanto Domingo Las Americas
19h 50m
1 stop
ORD12:04 pmChicago O'Hare Intl
Nov 30
ORD7:17 pmChicago O'Hare Intl
14h 58m
1 stop
SDQ12:15 pmSanto Domingo Las Americas
$424
Find similar
American Airlines
Dec 4
SDQ1:28 pmSanto Domingo Las Americas
11h 26m
2 stops
ORD10:54 pmChicago O'Hare Intl
Dec 7
ORD2:40 pmChicago O'Hare Intl
7h 10m
1 stop
SDQ11:50 pmSanto Domingo Las Americas
$426
Find similar
American Airlines
Nov 13
SDQ6:00 amSanto Domingo Las Americas
12h 05m
2 stops
ORD4:05 pmChicago O'Hare Intl
Nov 16
ORD7:10 amChicago O'Hare Intl
8h 14m
2 stops
SDQ5:24 pmSanto Domingo Las Americas
$429
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momondo Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Santo Domingo to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Wed 12/24

3:59 am-6:39 pm

1 stop16h 40m

Chicago O'Hare Intl

Sat 1/24

5:05 am-5:50 pm

1 stop10h 45m

$271

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Thu 12/4

4:21 pm-12:09 am

1 stop9h 48m

Chicago O'Hare Intl

Sun 12/7

5:00 am-3:23 pm

1 stop8h 23m

$290

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Mon 11/17

4:25 pm-9:47 am

1 stop19h 22m

Chicago O'Hare Intl

Wed 1/21

5:05 am-5:50 pm

1 stop10h 45m

$303

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Thu 12/4

4:21 pm-11:13 am

1 stop20h 52m

Chicago O'Hare Intl

Thu 12/11

5:00 am-3:23 pm

1 stop8h 23m

$307

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Wed 11/26

4:35 pm-4:25 pm

1 stop25h 50m

Chicago O'Hare Intl

Sat 12/6

3:26 pm-3:23 pm

1 stop21h 57m

$325

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Wed 11/26

4:35 pm-4:25 pm

1 stop25h 50m

Chicago O'Hare Intl

Sun 12/7

3:20 pm-3:23 pm

1 stop22h 03m

$331

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Sat 12/20

3:18 pm-10:04 pm

1 stop8h 46m

Chicago O'Hare Intl

Sun 1/4

7:41 pm-10:04 am

1 stop12h 23m

$406

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Tue 11/18

6:14 pm-12:04 pm

1 stop19h 50m

Chicago O'Hare Intl

Sun 11/30

7:17 pm-12:15 pm

1 stop14h 58m

$424

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Thu 12/4

1:28 pm-10:54 pm

2 stops11h 26m

Chicago O'Hare Intl

Sun 12/7

2:40 pm-11:50 pm

1 stop7h 10m

$426

Santo DomingoChicago

SDQ - ORD

SDQORD

Santo Domingo Las Americas

Sat 12/27

2:14 pm-12:05 am

1 stop11h 51m

Chicago O'Hare Intl

Sat 1/3

2:13 pm-2:17 am

1 stop10h 04m

$431

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santo Domingo to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of February is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Santo Domingo averaging around $437.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Saturday when prices can be found for as low as $471. This is often the case because there is less demand to fly during this day of the week. On the other hand, Wednesday is the most expensive day to depart from Santo Domingo because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $572.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Santo Domingo in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $440 when looking at flights departing in the afternoon. Try not to purchase tickets in the morning because they tend to be around $599. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Santo Domingo when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $506 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Santo Domingo for as low as $186 on momondo.

How have Santo Domingo to Chicago O'Hare Intl Airport flight prices changed over time?

As of October 2025, prices for Santo Domingo to Chicago O'Hare Intl Airport flights are approximately 77% more expensive when compared to flights at the same time last year.

When to book flights from Santo Domingo to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Santo Domingo to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santo Domingo to Chicago O'Hare Intl Airport (SDQ to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santo Domingo to Chicago O'Hare Intl Airport

Direct flights

None
There are no direct flights from Santo Domingo to Chicago O'Hare Intl Airport. There are no popular flight routes from Santo Domingo to Chicago O'Hare Intl Airport.
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  • How far is Santo Domingo Las Americas to Chicago O'Hare Intl by plane?

    Santo Domingo Las Americas and Chicago O'Hare Intl are 1935.5 mi apart from one another. By plane, this route typically takes 8h 10m.

  • When did momondo last update prices for flights from Santo Domingo Las Americas Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Santo Domingo Las Americas Airport to Chicago O'Hare Intl Airport are refreshed on a daily basis.

  • How many operators does momondo search for flights from Santo Domingo Las Americas Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Santo Domingo Las Americas Airport to Chicago O'Hare Intl Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Santo Domingo Las Americas Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The travel and health documents required for your trip to Chicago O'Hare Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Chicago O'Hare Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Santo Domingo to Chicago O'Hare Intl Airport?

Best airlines flying from Santo Domingo to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Santo Domingo to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Spirit AirlinesPriceFrom $189Free CancellationRating
6.3
8,115 reviews
Search Spirit Airlines flights
DeltaPriceFrom $449Free CancellationRating
7.9
7,998 reviews
Search Delta flights
American AirlinesPriceFrom $468Free CancellationRating
7.2
11,034 reviews
Search American Airlines flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
South Haven
Schaumburg
Rockford
Merrillville
Gurnee
Naperville
Rosemont
Kenosha
New Buffalo
Joliet
Oak Brook
Orland Park
Racine
Hammond
Tinley Park
Janesville
Aurora
Elgin
Benton Harbor

Why use momondo?

Why should I use momondo to find a flight deal from Santo Domingo to Chicago?

Finding the right flight to Chicago from Santo Domingo is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Chicago quick and easy, saving you time and money.

Can I find flights from Santo Domingo to Chicago with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Chicago from Santo Domingo with this policy.

How can momondo help me find flights from Santo Domingo to Chicago?

Once you have performed a search for Santo Domingo to Chicago flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Santo Domingo to Chicago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santo Domingo to Chicago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Chicago and let you know when they change.

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