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Cheap flights from Santa Cruz de la Sierra to Chicago from $454

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Chicago departing on 4/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Santa Cruz de la Sierra to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
3:35 am - 12:24 am
VVI
-
ORD
21h 49m
2 stops
Multiple Airlines Logo
11:20 pm - 2:30 am
ORD
-
VVI
26h 10m
1 stop
$805Multiple Airlines
Thu, Apr 16 - Mon, Apr 27
Multiple Airlines Logo
3:35 am - 5:35 am
VVI
-
ORD
27h 00m
3 stops
Multiple Airlines Logo
11:20 pm - 2:30 am
ORD
-
VVI
26h 10m
1 stop
$811Multiple Airlines
Thu, Apr 16 - Mon, Apr 27
Multiple Airlines Logo
3:35 am - 5:35 am
VVI
-
ORD
27h 00m
3 stops
Multiple Airlines Logo
7:50 am - 2:30 am
ORD
-
VVI
17h 40m
2 stops
$848Multiple Airlines
Thu, Apr 16 - Mon, Apr 27
Copa Airlines Logo
1:12 am - 1:57 pm
VVI
-
ORD
13h 45m
1 stop
Copa Airlines Logo
8:02 am - 10:40 pm
ORD
-
VVI
13h 38m
1 stop
$918Copa Airlines
Sun, Jul 5 - Mon, Jul 27
Avianca Logo
3:35 am - 9:20 pm
VVI
-
ORD
18h 45m
1 stop
Avianca Logo
11:20 pm - 2:30 am
ORD
-
VVI
26h 10m
1 stop
$936Avianca
Thu, Apr 16 - Sun, Apr 19
Avianca Logo
3:35 am - 9:20 pm
VVI
-
ORD
18h 45m
1 stop
Avianca Logo
11:20 pm - 2:30 am
ORD
-
VVI
26h 10m
1 stop
$940Avianca
Thu, Jul 30 - Sun, Aug 9
Avianca Logo
3:35 am - 9:20 pm
VVI
-
ORD
18h 45m
1 stop
Avianca Logo
11:20 pm - 2:30 am
ORD
-
VVI
26h 10m
1 stop
$948Avianca
Thu, Apr 16 - Sun, Apr 19
Multiple Airlines Logo
3:35 am - 5:35 am
VVI
-
ORD
27h 00m
3 stops
Multiple Airlines Logo
7:50 am - 6:35 am
ORD
-
VVI
21h 45m
3 stops
$972Multiple Airlines
Thu, Apr 16 - Mon, Apr 27
Multiple Airlines Logo
3:35 am - 11:12 am
VVI
-
ORD
32h 37m
2 stops
Multiple Airlines Logo
11:20 pm - 2:30 am
ORD
-
VVI
26h 10m
1 stop
$1,029Multiple Airlines
Thu, Jul 30 - Sun, Aug 9
Avianca Logo
3:35 am - 9:20 pm
VVI
-
ORD
18h 45m
1 stop
Avianca Logo
7:00 am - 2:30 am
ORD
-
VVI
18h 30m
2 stops
$1,047Avianca
Thu, Apr 16 - Sun, Apr 19

Copa Airlines flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport

Our best Copa Airlines deals on Santa Cruz de la Sierra to Chicago O'Hare Intl Airport flight tickets
Copa Airlines
Jul 5
VVI1:12 amSanta Cruz de la Sierra Viru Viru Intl
13h 45m
1 stop
ORD1:57 pmChicago O'Hare Intl
Jul 27
ORD8:02 amChicago O'Hare Intl
13h 38m
1 stop
VVI10:40 pmSanta Cruz de la Sierra Viru Viru Intl
$918
Copa Airlines
Mar 23
VVI1:14 amSanta Cruz de la Sierra Viru Viru Intl
13h 17m
1 stop
ORD1:31 pmChicago O'Hare Intl
Mar 28
ORD8:34 amChicago O'Hare Intl
13h 16m
1 stop
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
$1,068
Copa Airlines
Jul 30
VVI1:12 amSanta Cruz de la Sierra Viru Viru Intl
13h 45m
1 stop
ORD1:57 pmChicago O'Hare Intl
Aug 9
ORD8:02 amChicago O'Hare Intl
13h 38m
1 stop
VVI10:40 pmSanta Cruz de la Sierra Viru Viru Intl
$1,070

Avianca flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport

Our best Avianca deals on Santa Cruz de la Sierra to Chicago O'Hare Intl Airport flight tickets
Avianca
Apr 16
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
18h 45m
1 stop
ORD9:20 pmChicago O'Hare Intl
Apr 19
ORD11:20 pmChicago O'Hare Intl
26h 10m
1 stop
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
$936
Avianca
Jul 30
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
18h 45m
1 stop
ORD9:20 pmChicago O'Hare Intl
Aug 9
ORD11:20 pmChicago O'Hare Intl
26h 10m
1 stop
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
$940
Avianca
Apr 16
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
18h 45m
1 stop
ORD9:20 pmChicago O'Hare Intl
Apr 19
ORD11:20 pmChicago O'Hare Intl
26h 10m
1 stop
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
$948

momondo Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/16

3:35 am-12:24 am

2 stops21h 49m

Chicago O'Hare Intl

Mon 4/27

11:20 pm-2:30 am

1 stop26h 10m

$805

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/16

3:35 am-5:35 am

3 stops27h 00m

Chicago O'Hare Intl

Mon 4/27

11:20 pm-2:30 am

1 stop26h 10m

$811

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/16

3:35 am-5:35 am

3 stops27h 00m

Chicago O'Hare Intl

Mon 4/27

7:50 am-2:30 am

2 stops17h 40m

$848
Quickest round-trip

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Sun 7/5

1:12 am-1:57 pm

1 stop13h 45m

Chicago O'Hare Intl

Mon 7/27

8:02 am-10:40 pm

1 stop13h 38m

$918

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/16

3:35 am-9:20 pm

1 stop18h 45m

Chicago O'Hare Intl

Sun 4/19

11:20 pm-2:30 am

1 stop26h 10m

$936

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Thu 7/30

3:35 am-9:20 pm

1 stop18h 45m

Chicago O'Hare Intl

Sun 8/9

11:20 pm-2:30 am

1 stop26h 10m

$940

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/16

3:35 am-9:20 pm

1 stop18h 45m

Chicago O'Hare Intl

Sun 4/19

11:20 pm-2:30 am

1 stop26h 10m

$948

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/16

3:35 am-5:35 am

3 stops27h 00m

Chicago O'Hare Intl

Mon 4/27

7:50 am-6:35 am

3 stops21h 45m

$972

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Thu 7/30

3:35 am-11:12 am

2 stops32h 37m

Chicago O'Hare Intl

Sun 8/9

11:20 pm-2:30 am

1 stop26h 10m

$1,029

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/16

3:35 am-9:20 pm

1 stop18h 45m

Chicago O'Hare Intl

Sun 4/19

7:00 am-2:30 am

2 stops18h 30m

$1,047

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Santa Cruz de la Sierra to Chicago O'Hare Intl Airport flights?

You could potentially save up to 22% on your flight if you consider stops on a Santa Cruz de la Sierra to Chicago O'Hare Intl Airport flight.

When to book flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Cruz de la Sierra to Chicago O'Hare Intl Airport (VVI to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport

Fastest flight time

18h 45m

Direct flights

None
The fastest flight from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport takes 18h 45m
There are no direct flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport. There are no popular flight routes from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport.
Search flight deals

  • How far is Santa Cruz de la Sierra Viru Viru Intl to Chicago O'Hare Intl by plane?

    Chicago O'Hare Intl is 4419.8 mi away from Santa Cruz de la Sierra Viru Viru Intl. In terms of flight time, this usually takes a little over 18h 45m.

  • When did momondo last update prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago O'Hare Intl Airport were last updated today.

  • How many operators does momondo search for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago O'Hare Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The travel and health documents you'll need for your trip to Chicago O'Hare Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago O'Hare Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport?

Best airlines flying from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $690Free CancellationRating
7.5
1,571 reviews
Search Copa Airlines flights

Traveling to a place near Chicago?

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Elgin
South Holland

Why use momondo?

Why should I use momondo to find a flight deal from Santa Cruz de la Sierra to Chicago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Chicago from Santa Cruz de la Sierra.

Can I find flights from Santa Cruz de la Sierra to Chicago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santa Cruz de la Sierra to Chicago flights to just show those with flexible booking policies.

How can momondo help me find flights from Santa Cruz de la Sierra to Chicago?

momondo helps you find the best flight between Santa Cruz de la Sierra and Chicago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santa Cruz de la Sierra to Chicago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santa Cruz de la Sierra to Chicago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Chicago and let you know when they change.

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