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Cheap flights from Santa Cruz de la Sierra to Chicago from $398

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Cruz de la Sierra to Chicago departing on 2/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Santa Cruz de la Sierra to Chicago

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
11:48 am - 1:13 am
VVI
-
ORD
14h 25m1 stop
Copa Airlines Logo
3:21 pm - 3:40 am
ORD
-
VVI
11h 19m1 stop
$691Copa Airlines
Thu, Apr 16 - Sun, Apr 19
United Airlines Logo
11:42 am - 6:51 pm
VVI
-
ORD
32h 09m2 stops
United Airlines Logo
9:10 pm - 10:50 pm
ORD
-
VVI
24h 40m2 stops
$696United Airlines
Tue, Mar 24 - Sat, Mar 28
United Airlines Logo
11:42 am - 9:54 am
VVI
-
ORD
23h 12m2 stops
United Airlines Logo
9:05 pm - 10:50 pm
ORD
-
VVI
24h 45m2 stops
$729United Airlines
Tue, Mar 24 - Sat, Mar 28
United Airlines Logo
11:44 am - 9:28 pm
VVI
-
ORD
35h 44m2 stops
United Airlines Logo
9:05 pm - 10:50 pm
ORD
-
VVI
24h 45m2 stops
$784United Airlines
Thu, Feb 26 - Sat, Mar 21
Avianca Logo
3:40 am - 8:20 pm
VVI
-
ORD
18h 40m1 stop
Avianca Logo
11:20 pm - 2:35 am
ORD
-
VVI
26h 15m1 stop
$814Avianca
Wed, Feb 25 - Sat, Mar 21
Avianca Logo
2:55 am - 1:15 pm
VVI
-
ORD
11h 20m1 stop
Avianca Logo
10:35 am - 1:50 am
ORD
-
VVI
14h 15m2 stops
$832Avianca
Wed, Apr 15 - Sun, Apr 19
United Airlines Logo
11:48 am - 11:11 pm
VVI
-
ORD
36h 23m2 stops
United Airlines Logo
9:15 pm - 3:40 am
ORD
-
VVI
29h 25m2 stops
$855United Airlines
Thu, Apr 16 - Sun, Apr 19
Multiple Airlines Logo
3:40 am - 8:20 pm
VVI
-
ORD
18h 40m1 stop
Multiple Airlines Logo
5:45 am - 2:35 am
ORD
-
VVI
42h 50m2 stops
$873Multiple Airlines
Sun, Dec 21 - Mon, Jan 5
Copa Airlines Logo
1:15 am - 12:31 pm
VVI
-
ORD
13h 16m1 stop
Copa Airlines Logo
8:34 am - 10:50 pm
ORD
-
VVI
13h 16m1 stop
$884Copa Airlines
Wed, Feb 25 - Sat, Mar 21
Avianca Logo
3:40 am - 8:20 pm
VVI
-
ORD
18h 40m1 stop
Avianca Logo
7:15 am - 2:35 am
ORD
-
VVI
17h 20m2 stops
$893Avianca
Sat, Dec 20 - Fri, Jan 9

Avianca flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport

Our best Avianca deals on Santa Cruz de la Sierra to Chicago O'Hare Intl Airport flight tickets
Avianca
Feb 25
VVI3:40 amSanta Cruz de la Sierra Viru Viru Intl
18h 40m
1 stop
ORD8:20 pmChicago O'Hare Intl
Mar 21
ORD11:20 pmChicago O'Hare Intl
26h 15m
1 stop
VVI2:35 amSanta Cruz de la Sierra Viru Viru Intl
$814
Find similar
Avianca
Apr 15
VVI2:55 amSanta Cruz de la Sierra Viru Viru Intl
11h 20m
1 stop
ORD1:15 pmChicago O'Hare Intl
Apr 19
ORD10:35 amChicago O'Hare Intl
14h 15m
2 stops
VVI1:50 amSanta Cruz de la Sierra Viru Viru Intl
$832
Find similar
Avianca
Dec 20
VVI3:40 amSanta Cruz de la Sierra Viru Viru Intl
18h 40m
1 stop
ORD8:20 pmChicago O'Hare Intl
Jan 9
ORD7:15 amChicago O'Hare Intl
17h 20m
2 stops
VVI2:35 amSanta Cruz de la Sierra Viru Viru Intl
$893
Find similar

Copa Airlines flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport

Our best Copa Airlines deals on Santa Cruz de la Sierra to Chicago O'Hare Intl Airport flight tickets
Copa Airlines
Apr 15
VVI1:15 amSanta Cruz de la Sierra Viru Viru Intl
13h 43m
1 stop
ORD1:58 pmChicago O'Hare Intl
Apr 19
ORD8:06 amChicago O'Hare Intl
13h 36m
1 stop
VVI10:42 pmSanta Cruz de la Sierra Viru Viru Intl
$691
Find similar
Copa Airlines
Feb 25
VVI1:15 amSanta Cruz de la Sierra Viru Viru Intl
13h 16m
1 stop
ORD12:31 pmChicago O'Hare Intl
Mar 21
ORD8:34 amChicago O'Hare Intl
13h 16m
1 stop
VVI10:50 pmSanta Cruz de la Sierra Viru Viru Intl
$884
Find similar
Copa Airlines
Dec 20
VVI1:09 amSanta Cruz de la Sierra Viru Viru Intl
13h 43m
1 stop
ORD12:52 pmChicago O'Hare Intl
Jan 9
ORD2:13 pmChicago O'Hare Intl
11h 31m
1 stop
VVI3:44 amSanta Cruz de la Sierra Viru Viru Intl
$1,045
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/16

11:48 am-1:13 am

1 stop14h 25m

Chicago O'Hare Intl

Sun 4/19

3:21 pm-3:40 am

1 stop11h 19m

$691

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/24

11:42 am-6:51 pm

2 stops32h 09m

Chicago O'Hare Intl

Sat 3/28

9:10 pm-10:50 pm

2 stops24h 40m

$696

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Tue 3/24

11:42 am-9:54 am

2 stops23h 12m

Chicago O'Hare Intl

Sat 3/28

9:05 pm-10:50 pm

2 stops24h 45m

$729

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Thu 2/26

11:44 am-9:28 pm

2 stops35h 44m

Chicago O'Hare Intl

Sat 3/21

9:05 pm-10:50 pm

2 stops24h 45m

$784

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Wed 2/25

3:40 am-8:20 pm

1 stop18h 40m

Chicago O'Hare Intl

Sat 3/21

11:20 pm-2:35 am

1 stop26h 15m

$814

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Wed 4/15

2:55 am-1:15 pm

1 stop11h 20m

Chicago O'Hare Intl

Sun 4/19

10:35 am-1:50 am

2 stops14h 15m

$832

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/16

11:48 am-11:11 pm

2 stops36h 23m

Chicago O'Hare Intl

Sun 4/19

9:15 pm-3:40 am

2 stops29h 25m

$855

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Sun 12/21

3:40 am-8:20 pm

1 stop18h 40m

Chicago O'Hare Intl

Mon 1/5

5:45 am-2:35 am

2 stops42h 50m

$873

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Wed 2/25

1:15 am-12:31 pm

1 stop13h 16m

Chicago O'Hare Intl

Sat 3/21

8:34 am-10:50 pm

1 stop13h 16m

$884

Santa Cruz de la SierraChicago

VVI - ORD

VVIORD

Santa Cruz de la Sierra Viru Viru Intl

Sat 12/20

3:40 am-8:20 pm

1 stop18h 40m

Chicago O'Hare Intl

Fri 1/9

7:15 am-2:35 am

2 stops17h 20m

$893

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Sunday when prices can be found for as low as $667. This is often the case because there is less demand to fly during this day of the week. On the other hand, Wednesday is the most expensive day to depart from Santa Cruz de la Sierra because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,268.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Santa Cruz de la Sierra in the morning is the least expensive time of day to depart. momondo users have found prices as low as $835 when looking at flights departing in the morning. Try not to purchase tickets in the evening because they tend to be around $937. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Santa Cruz de la Sierra to Chicago O'Hare Intl Airport flights?

You could potentially save up to 7% on your flight if you consider stops on a Santa Cruz de la Sierra to Chicago O'Hare Intl Airport flight.

When to book flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Cruz de la Sierra to Chicago O'Hare Intl Airport (VVI to ORD) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport

Fastest flight time

14h 25m

Direct flights

None
The fastest flight from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport takes 14h 25m
There are no direct flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport. There are no popular flight routes from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport.
Search flight deals

  • How far is Santa Cruz de la Sierra Viru Viru Intl to Chicago O'Hare Intl by plane?

    Chicago O'Hare Intl is 4419.8 mi away from Santa Cruz de la Sierra Viru Viru Intl. In terms of flight time, this usually takes a little over 14h 25m.

  • When did momondo last update prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago O'Hare Intl Airport?

    Prices for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago O'Hare Intl Airport were last updated today.

  • How many operators does momondo search for flights from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago O'Hare Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Santa Cruz de la Sierra Viru Viru Intl Airport to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The travel and health documents you'll need for your trip to Chicago O'Hare Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Chicago O'Hare Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport?

Best airlines flying from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $690Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
South Haven
Schaumburg
Rockford
Merrillville
Gurnee
Naperville
Rosemont
Kenosha
New Buffalo
Joliet
Oak Brook
Orland Park
Racine
Hammond
Tinley Park
Janesville
Aurora
Elgin
Benton Harbor

Why use momondo?

Why should I use momondo to find a flight deal from Santa Cruz de la Sierra to Chicago?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Chicago from Santa Cruz de la Sierra.

Can I find flights from Santa Cruz de la Sierra to Chicago with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Santa Cruz de la Sierra to Chicago flights to just show those with flexible booking policies.

How can momondo help me find flights from Santa Cruz de la Sierra to Chicago?

momondo helps you find the best flight between Santa Cruz de la Sierra and Chicago by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Santa Cruz de la Sierra to Chicago right now. Can momondo alert me if prices change?

If you are not ready to book a flight from Santa Cruz de la Sierra to Chicago now, use our insights above to find helpful tips or alternatively set up a price alert, where momondo will track prices on flights to Chicago and let you know when they change.

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