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Cheap flights from Santa Ana, California to Guayaquil from $455

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Santa Ana, California to Guayaquil departing on 7/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Find the cheapest flights from Santa Ana, California to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
3:25 pm - 8:56 pm
SNA
-
GYE
26h 31m
2 stops
United Airlines Logo
12:24 pm - 9:53 pm
GYE
-
SNA
36h 29m
2 stops
$829United Airlines
Mon, Nov 2 - Thu, Nov 5
United Airlines Logo
3:25 pm - 8:56 pm
SNA
-
GYE
26h 31m
2 stops
United Airlines Logo
12:24 pm - 9:53 pm
GYE
-
SNA
36h 29m
2 stops
$839United Airlines
Mon, Nov 2 - Thu, Nov 5
United Airlines Logo
3:25 pm - 11:40 pm
SNA
-
GYE
29h 15m
2 stops
United Airlines Logo
2:47 pm - 8:19 pm
GYE
-
SNA
56h 32m
3 stops
$849United Airlines
Mon, Nov 2 - Thu, Nov 5
United Airlines Logo
3:25 pm - 11:40 pm
SNA
-
GYE
29h 15m
2 stops
United Airlines Logo
2:47 pm - 8:19 pm
GYE
-
SNA
56h 32m
3 stops
$860United Airlines
Mon, Nov 2 - Thu, Nov 5
Copa Airlines Logo
7:45 am - 11:38 pm
SNA
-
GYE
13h 53m
2 stops
Copa Airlines Logo
4:13 am - 9:45 pm
GYE
-
SNA
19h 32m
2 stops
$989Copa Airlines
Fri, Jul 31 - Sun, Aug 9
United Airlines Logo
7:45 am - 11:38 pm
SNA
-
GYE
13h 53m
2 stops
United Airlines Logo
2:37 pm - 8:55 pm
GYE
-
SNA
32h 18m
3 stops
$1,411United Airlines
Fri, Jul 31 - Sun, Aug 9
United Airlines Logo
8:45 am - 5:31 pm
SNA
-
GYE
54h 46m
3 stops
United Airlines Logo
2:37 pm - 8:55 pm
GYE
-
SNA
32h 18m
3 stops
$1,441United Airlines
Fri, Jul 31 - Sun, Aug 9
Multiple Airlines Logo
10:28 am - 7:45 am
SNA
-
GYE
19h 17m
2 stops
Multiple Airlines Logo
8:00 pm - 4:45 pm
GYE
-
SNA
22h 45m
2 stops
$1,556Multiple Airlines
Thu, Jul 23 - Tue, Sep 29
Delta Logo
7:15 am - 7:14 am
SNA
-
GYE
21h 59m
2 stops
Delta Logo
4:19 pm - 11:10 am
GYE
-
SNA
20h 51m
1 stop
$3,027Delta
Fri, Jul 31 - Sun, Aug 9
LATAM Airlines Logo
2:00 pm - 8:34 am
SNA
-
GYE
40h 34m
2 stops
LATAM Airlines Logo
4:05 pm - 12:33 pm
GYE
-
SNA
22h 28m
2 stops
$4,267LATAM Airlines
Thu, Jul 23 - Tue, Sep 29

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LATAM Airlines flights from Santa Ana, California to Guayaquil

Our best LATAM Airlines deals on Santa Ana, California to Guayaquil flight tickets
LATAM Airlines
Jul 23
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
40h 34m
2 stops
GYE8:34 amGuayaquil Jose Joaquin de Olmedo
Sep 29
GYE4:05 pmGuayaquil Jose Joaquin de Olmedo
22h 28m
2 stops
SNA12:33 pmSanta Ana J. Wayne/Orange Cnty
$4,267
LATAM Airlines
Jun 28
SNA2:00 pmSanta Ana J. Wayne/Orange Cnty
42h 30m
2 stops
GYE10:30 amGuayaquil Jose Joaquin de Olmedo
Jul 13
GYE5:28 pmGuayaquil Jose Joaquin de Olmedo
27h 32m
2 stops
SNA7:00 pmSanta Ana J. Wayne/Orange Cnty
$10,427

United Airlines flights from Santa Ana, California to Guayaquil

Our best United Airlines deals on Santa Ana, California to Guayaquil flight tickets
United Airlines
Nov 2
SNA3:25 pmSanta Ana J. Wayne/Orange Cnty
26h 31m
2 stops
GYE8:56 pmGuayaquil Jose Joaquin de Olmedo
Nov 5
GYE12:24 pmGuayaquil Jose Joaquin de Olmedo
36h 29m
2 stops
SNA9:53 pmSanta Ana J. Wayne/Orange Cnty
$829
United Airlines
Nov 2
SNA3:25 pmSanta Ana J. Wayne/Orange Cnty
26h 31m
2 stops
GYE8:56 pmGuayaquil Jose Joaquin de Olmedo
Nov 5
GYE12:24 pmGuayaquil Jose Joaquin de Olmedo
36h 29m
2 stops
SNA9:53 pmSanta Ana J. Wayne/Orange Cnty
$839
United Airlines
Nov 2
SNA3:25 pmSanta Ana J. Wayne/Orange Cnty
26h 31m
2 stops
GYE8:56 pmGuayaquil Jose Joaquin de Olmedo
Nov 5
GYE2:47 pmGuayaquil Jose Joaquin de Olmedo
56h 32m
3 stops
SNA8:19 pmSanta Ana J. Wayne/Orange Cnty
$849

momondo Fare Finder

 
Customize your flight search to find flights from Santa Ana, California to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 12, 2026.
Use the filters below to find and compare flights from Santa Ana, California to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa AnaGuayaquil

SNA - GYE

SNAGYE

Santa Ana J. Wayne/Orange Cnty

Mon 11/2

3:25 pm-8:56 pm

2 stops26h 31m

Guayaquil Jose Joaquin de Olmedo

Thu 11/5

12:24 pm-9:53 pm

2 stops36h 29m

$829

Santa AnaGuayaquil

SNA - GYE

SNAGYE

Santa Ana J. Wayne/Orange Cnty

Mon 11/2

3:25 pm-8:56 pm

2 stops26h 31m

Guayaquil Jose Joaquin de Olmedo

Thu 11/5

12:24 pm-9:53 pm

2 stops36h 29m

$839

Santa AnaGuayaquil

SNA - GYE

SNAGYE

Santa Ana J. Wayne/Orange Cnty

Mon 11/2

3:25 pm-11:40 pm

2 stops29h 15m

Guayaquil Jose Joaquin de Olmedo

Thu 11/5

2:47 pm-8:19 pm

3 stops56h 32m

$849

Santa AnaGuayaquil

SNA - GYE

SNAGYE

Santa Ana J. Wayne/Orange Cnty

Mon 11/2

3:25 pm-11:40 pm

2 stops29h 15m

Guayaquil Jose Joaquin de Olmedo

Thu 11/5

2:47 pm-8:19 pm

3 stops56h 32m

$860
Quickest round-trip

Santa AnaGuayaquil

SNA - GYE

SNAGYE

Santa Ana J. Wayne/Orange Cnty

Fri 7/31

7:45 am-11:38 pm

2 stops13h 53m

Guayaquil Jose Joaquin de Olmedo

Sun 8/9

4:13 am-9:45 pm

2 stops19h 32m

$989

Santa AnaGuayaquil

SNA - GYE

SNAGYE

Santa Ana J. Wayne/Orange Cnty

Fri 7/31

7:45 am-11:38 pm

2 stops13h 53m

Guayaquil Jose Joaquin de Olmedo

Sun 8/9

2:37 pm-8:55 pm

3 stops32h 18m

$1,411

Santa AnaGuayaquil

SNA - GYE

SNAGYE

Santa Ana J. Wayne/Orange Cnty

Fri 7/31

8:45 am-5:31 pm

3 stops54h 46m

Guayaquil Jose Joaquin de Olmedo

Sun 8/9

2:37 pm-8:55 pm

3 stops32h 18m

$1,441

Santa AnaGuayaquil

SNA - GYE

SNAGYE

Santa Ana J. Wayne/Orange Cnty

Thu 7/23

10:28 am-7:45 am

2 stops19h 17m

Guayaquil Jose Joaquin de Olmedo

Tue 9/29

8:00 pm-4:45 pm

2 stops22h 45m

$1,556

Santa AnaGuayaquil

SNA - GYE

SNAGYE

Santa Ana J. Wayne/Orange Cnty

Fri 7/31

7:15 am-7:14 am

2 stops21h 59m

Guayaquil Jose Joaquin de Olmedo

Sun 8/9

4:19 pm-11:10 am

1 stop20h 51m

$3,027

Santa AnaGuayaquil

SNA - GYE

SNAGYE

Santa Ana J. Wayne/Orange Cnty

Thu 7/23

2:00 pm-8:34 am

2 stops40h 34m

Guayaquil Jose Joaquin de Olmedo

Tue 9/29

4:05 pm-12:33 pm

2 stops22h 28m

$4,267

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from Santa Ana, California to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest airline that flies from Santa Ana J. Wayne/Orange Cnty to Guayaquil Jose Joaquin de Olmedo?

United Airlines is the most popular carrier operating from Santa Ana J. Wayne/Orange Cnty to Guayaquil Jose Joaquin de Olmedo

What airlines fly to Guayaquil?

Copa Airlines, Avianca and American Airlines are the top three most popular airlines that fly to Guayaquil from Santa Ana, California according to our data. Copa Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Guayaquil. Keep in mind that there are 5 different airlines that fly to Guayaquil on a routine basis, so you have a few additional options to choose from.

When to book flights from Santa Ana, California to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from Santa Ana, California to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Santa Ana, California to Guayaquil (SNA to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Santa Ana, California to Guayaquil

Fastest flight time

19h 17m

Direct flights

None
The fastest flight from Santa Ana, California to Guayaquil takes 19h 17m
There are no direct flights from Santa Ana, California to Guayaquil. There are no popular flight routes from Santa Ana, California to Guayaquil.
Search flight deals

Frequently asked questions about flying from Santa Ana, California to Guayaquil

  • How far is Santa Ana J. Wayne/Orange Cnty to Guayaquil Jose Joaquin de Olmedo by plane?

    The straight-line distance from Santa Ana J. Wayne/Orange Cnty to Guayaquil Jose Joaquin de Olmedo is 3499.1 mi. In terms of flight time, this usually takes a little over 19h 17m.

  • When did momondo last update prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from Santa Ana J. Wayne/Orange Cnty Airport to Guayaquil Jose Joaquin de Olmedo Airport were last updated today.

  • How old do you have to be to fly from Santa Ana J. Wayne/Orange Cnty Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Santa Ana J. Wayne/Orange Cnty Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The travel and health documents you'll need for your trip to Guayaquil Jose Joaquin de Olmedo Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Santa Ana to Guayaquil?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Santa Ana to Guayaquil. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Santa Ana to Guayaquil with flexible booking policies on momondo?

All flight searches from Santa Ana to Guayaquil on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Santa Ana to Guayaquil?

momondo provides multiple filters to help you find the best flight to Guayaquil from Santa Ana. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Santa Ana to Guayaquil right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Guayaquil, momondo offers a useful price alert feature which will track prices for flights to Guayaquil from Santa Ana and alert you when they change.

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