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Cheap flights from San Francisco to Santo Domingo from $202

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santo Domingo departing on 5/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

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Find the cheapest flights from San Francisco to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
8:40 pm - 8:09 am
SFO
-
SDQ
8h 29m
1 stop
JetBlue Logo
5:01 am - 8:21 pm
SDQ
-
SFO
18h 20m
1 stop
$491JetBlue
Tue, May 26 - Tue, Jun 2
JetBlue Logo
11:05 pm - 12:28 pm
SFO
-
SDQ
10h 23m
1 stop
JetBlue Logo
7:30 pm - 9:23 am
SDQ
-
SFO
16h 53m
1 stop
$499JetBlue
Mon, Apr 27 - Wed, Apr 29
JetBlue Logo
8:44 pm - 2:55 pm
SFO
-
SDQ
15h 11m
1 stop
JetBlue Logo
1:40 pm - 11:51 pm
SDQ
-
SFO
13h 11m
1 stop
$501JetBlue
Mon, May 11 - Thu, May 14
JetBlue Logo
8:45 pm - 2:55 pm
SFO
-
SDQ
15h 10m
1 stop
JetBlue Logo
8:32 pm - 9:25 am
SDQ
-
SFO
15h 53m
1 stop
$519JetBlue
Tue, May 5 - Fri, May 8
JetBlue Logo
2:53 pm - 9:42 am
SFO
-
SDQ
15h 49m
1 stop
JetBlue Logo
5:01 am - 7:23 pm
SDQ
-
SFO
17h 22m
1 stop
$525JetBlue
Sat, Jun 6 - Sat, Jun 13
JetBlue Logo
8:25 pm - 10:41 am
SFO
-
SDQ
11h 16m
1 stop
JetBlue Logo
7:22 pm - 9:10 am
SDQ
-
SFO
16h 48m
1 stop
$532JetBlue
Mon, Sep 14 - Sun, Sep 20
JetBlue Logo
10:50 pm - 1:58 pm
SFO
-
SDQ
12h 08m
1 stop
JetBlue Logo
5:50 am - 7:21 pm
SDQ
-
SFO
16h 31m
1 stop
$541JetBlue
Fri, May 1 - Fri, May 8
Avianca Logo
11:55 pm - 5:55 pm
SFO
-
SDQ
15h 00m
2 stops
Avianca Logo
6:50 pm - 12:50 pm
SDQ
-
SFO
21h 00m
2 stops
$542Avianca
Sun, Apr 19 - Sat, Apr 25
Avianca Logo
11:55 pm - 5:55 pm
SFO
-
SDQ
15h 00m
2 stops
Avianca Logo
6:50 pm - 12:50 pm
SDQ
-
SFO
21h 00m
2 stops
$544Avianca
Wed, Apr 22 - Mon, Apr 27
JetBlue Logo
8:44 pm - 2:55 pm
SFO
-
SDQ
15h 11m
1 stop
JetBlue Logo
1:40 pm - 11:51 pm
SDQ
-
SFO
13h 11m
1 stop
$545JetBlue
Mon, May 11 - Thu, May 14

Copa Airlines flights from San Francisco to Santo Domingo

Our best Copa Airlines deals on San Francisco to Santo Domingo flight tickets
Copa Airlines
Aug 21
SFO1:12 amSan Francisco
12h 03m
1 stop
SDQ4:15 pmSanto Domingo Las Americas
Sep 5
SDQ12:42 pmSanto Domingo Las Americas
13h 58m
1 stop
SFO11:40 pmSan Francisco
$563
Copa Airlines
Aug 9
SFO8:21 pmSan Francisco
12h 21m
1 stop
SDQ11:42 amSanto Domingo Las Americas
Aug 13
SDQ2:17 pmSanto Domingo Las Americas
12h 23m
1 stop
SFO11:40 pmSan Francisco
$580
Copa Airlines
Aug 16
SFO8:21 pmSan Francisco
12h 21m
1 stop
SDQ11:42 amSanto Domingo Las Americas
Aug 22
SDQ12:43 pmSanto Domingo Las Americas
13h 57m
1 stop
SFO11:40 pmSan Francisco
$583

JetBlue flights from San Francisco to Santo Domingo

Our best JetBlue deals on San Francisco to Santo Domingo flight tickets
JetBlue
May 26
SFO8:40 pmSan Francisco
8h 29m
1 stop
SDQ8:09 amSanto Domingo Las Americas
Jun 2
SDQ5:01 amSanto Domingo Las Americas
18h 20m
1 stop
SFO8:21 pmSan Francisco
$491
JetBlue
Apr 27
SFO11:05 pmSan Francisco
10h 23m
1 stop
SDQ12:28 pmSanto Domingo Las Americas
Apr 29
SDQ7:30 pmSanto Domingo Las Americas
16h 53m
1 stop
SFO9:23 amSan Francisco
$499
JetBlue
May 11
SFO8:44 pmSan Francisco
15h 11m
1 stop
SDQ2:55 pmSanto Domingo Las Americas
May 14
SDQ1:40 pmSanto Domingo Las Americas
13h 11m
1 stop
SFO11:51 pmSan Francisco
$501

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 5/26

8:40 pm-8:09 am

1 stop8h 29m

Santo Domingo Las Americas

Tue 6/2

5:01 am-8:21 pm

1 stop18h 20m

$491

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Mon 4/27

11:05 pm-12:28 pm

1 stop10h 23m

Santo Domingo Las Americas

Wed 4/29

7:30 pm-9:23 am

1 stop16h 53m

$499

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Mon 5/11

8:44 pm-2:55 pm

1 stop15h 11m

Santo Domingo Las Americas

Thu 5/14

1:40 pm-11:51 pm

1 stop13h 11m

$501

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 5/5

8:45 pm-2:55 pm

1 stop15h 10m

Santo Domingo Las Americas

Fri 5/8

8:32 pm-9:25 am

1 stop15h 53m

$519

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 6/6

2:53 pm-9:42 am

1 stop15h 49m

Santo Domingo Las Americas

Sat 6/13

5:01 am-7:23 pm

1 stop17h 22m

$525

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Mon 9/14

8:25 pm-10:41 am

1 stop11h 16m

Santo Domingo Las Americas

Sun 9/20

7:22 pm-9:10 am

1 stop16h 48m

$532

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Fri 5/1

10:50 pm-1:58 pm

1 stop12h 08m

Santo Domingo Las Americas

Fri 5/8

5:50 am-7:21 pm

1 stop16h 31m

$541

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sun 4/19

11:55 pm-5:55 pm

2 stops15h 00m

Santo Domingo Las Americas

Sat 4/25

6:50 pm-12:50 pm

2 stops21h 00m

$542

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Wed 4/22

11:55 pm-5:55 pm

2 stops15h 00m

Santo Domingo Las Americas

Mon 4/27

6:50 pm-12:50 pm

2 stops21h 00m

$544

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Mon 5/11

8:44 pm-2:55 pm

1 stop15h 11m

Santo Domingo Las Americas

Thu 5/14

1:40 pm-11:51 pm

1 stop13h 11m

$545

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from San Francisco to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in October, then you should wait until January to fly from San Francisco, when ticket prices are also cheap, with an average price of $550.

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $658 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from San Francisco for as low as $447 on momondo.

Can stopping save me money on San Francisco to Santo Domingo flights?

You could potentially save up to 9% on your flight if you consider stops on a San Francisco to Santo Domingo flight.

How have San Francisco to Santo Domingo flight prices changed over time?

As of April 2026, prices for San Francisco to Santo Domingo flights are approximately 12% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santo Domingo (SFO to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santo Domingo

Fastest flight time

8h 29m

Direct flights

None
The fastest flight from San Francisco to Santo Domingo takes 8h 29m
There are no direct flights from San Francisco to Santo Domingo. There are no popular flight routes from San Francisco to Santo Domingo.
Search flight deals

Frequently asked questions about flying from San Francisco to Santo Domingo

  • How far is San Francisco to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 3410.4 mi away from San Francisco. A reasonable flight in good conditions will take 8h 29m.

  • When did momondo last update prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

    Prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from San Francisco Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santo Domingo?

Best airlines flying from San Francisco to Santo Domingo

Compare and see reviews for airlines that fly from San Francisco to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $313Free CancellationRating
6.5
2,503 reviews
Search Avianca flights
Copa AirlinesPriceFrom $420Free CancellationRating
7.5
1,575 reviews
Search Copa Airlines flights
JetBluePriceFrom $433Free CancellationRating
7.2
2,925 reviews
Search JetBlue flights
DeltaPriceFrom $587Free CancellationRating
7.9
8,392 reviews
Search Delta flights
American AirlinesPriceFrom $617Free CancellationRating
7.1
11,563 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Santo Domingo for you.

Can I find flights from San Francisco to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santo Domingo?

Once you have performed a search for San Francisco to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from San Francisco are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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