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Cheap flights from San Francisco to Santo Domingo from $257

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santo Domingo departing on 5/26. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
1:12 am - 4:15 pm
SFO
-
SDQ
12h 03m
1 stop
Copa Airlines Logo
6:06 am - 11:40 pm
SDQ
-
SFO
20h 34m
1 stop
$500Copa Airlines
Mon, Aug 31 - Tue, Sep 15
Copa Airlines Logo
8:21 pm - 1:12 pm
SFO
-
SDQ
13h 51m
1 stop
Copa Airlines Logo
2:11 pm - 11:40 pm
SDQ
-
SFO
12h 29m
1 stop
$523Copa Airlines
Thu, Oct 22 - Thu, Oct 29
Avianca Logo
2:15 pm - 11:50 am
SFO
-
SDQ
18h 35m
2 stops
Avianca Logo
6:50 pm - 12:50 pm
SDQ
-
SFO
21h 00m
2 stops
$541Avianca
Sat, May 9 - Fri, May 22
Avianca Logo
2:15 pm - 11:50 am
SFO
-
SDQ
18h 35m
2 stops
Avianca Logo
6:50 pm - 12:50 pm
SDQ
-
SFO
21h 00m
2 stops
$542Avianca
Wed, May 27 - Wed, Jun 3
Avianca Logo
11:55 pm - 5:55 pm
SFO
-
SDQ
15h 00m
2 stops
Avianca Logo
6:50 pm - 12:50 pm
SDQ
-
SFO
21h 00m
2 stops
$550Avianca
Sat, Aug 8 - Sat, Aug 22
Avianca Logo
2:15 pm - 11:50 am
SFO
-
SDQ
18h 35m
2 stops
Avianca Logo
6:50 pm - 12:50 pm
SDQ
-
SFO
21h 00m
2 stops
$558Avianca
Sun, May 10 - Fri, May 29
Avianca Logo
2:15 pm - 11:50 am
SFO
-
SDQ
18h 35m
2 stops
Avianca Logo
6:50 pm - 12:50 pm
SDQ
-
SFO
21h 00m
2 stops
$560Avianca
Thu, May 21 - Mon, May 25
JetBlue Logo
9:33 pm - 12:28 pm
SFO
-
SDQ
11h 55m
1 stop
JetBlue Logo
9:20 am - 12:33 am
SDQ
-
SFO
18h 13m
1 stop
$566JetBlue
Sat, May 9 - Fri, May 22
Avianca Logo
11:55 pm - 5:55 pm
SFO
-
SDQ
15h 00m
2 stops
Avianca Logo
6:50 pm - 12:50 pm
SDQ
-
SFO
21h 00m
2 stops
$568Avianca
Sat, Aug 8 - Sat, Aug 22
Avianca Logo
2:15 pm - 11:50 am
SFO
-
SDQ
18h 35m
2 stops
Avianca Logo
5:45 pm - 1:00 pm
SDQ
-
SFO
22h 15m
2 stops
$569Avianca
Tue, Oct 13 - Thu, Oct 29

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JetBlue flights from San Francisco to Santo Domingo

Our best JetBlue deals on San Francisco to Santo Domingo flight tickets
JetBlue
May 23
SFO11:37 amSan Francisco
17h 32m
1 stop
SDQ8:09 amSanto Domingo Las Americas
May 27
SDQ6:47 pmSanto Domingo Las Americas
18h 25m
1 stop
SFO10:12 amSan Francisco
$590
JetBlue
May 23
SFO11:37 amSan Francisco
17h 32m
1 stop
SDQ8:09 amSanto Domingo Las Americas
May 30
SDQ9:20 amSanto Domingo Las Americas
18h 13m
1 stop
SFO12:33 amSan Francisco
$612
JetBlue
May 27
SFO8:40 pmSan Francisco
8h 29m
1 stop
SDQ8:09 amSanto Domingo Las Americas
Jun 2
SDQ3:11 amSanto Domingo Las Americas
20h 10m
1 stop
SFO8:21 pmSan Francisco
$628

Copa Airlines flights from San Francisco to Santo Domingo

Our best Copa Airlines deals on San Francisco to Santo Domingo flight tickets
Copa Airlines
Aug 31
SFO1:12 amSan Francisco
12h 03m
1 stop
SDQ4:15 pmSanto Domingo Las Americas
Sep 15
SDQ6:06 amSanto Domingo Las Americas
20h 34m
1 stop
SFO11:40 pmSan Francisco
$500
Copa Airlines
Oct 22
SFO8:21 pmSan Francisco
13h 51m
1 stop
SDQ1:12 pmSanto Domingo Las Americas
Oct 29
SDQ2:11 pmSanto Domingo Las Americas
12h 29m
1 stop
SFO11:40 pmSan Francisco
$523
Copa Airlines
Aug 7
SFO1:12 amSan Francisco
12h 03m
1 stop
SDQ4:15 pmSanto Domingo Las Americas
Aug 22
SDQ12:13 pmSanto Domingo Las Americas
14h 27m
1 stop
SFO11:40 pmSan Francisco
$620

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Mon 8/31

1:12 am-4:15 pm

1 stop12h 03m

Santo Domingo Las Americas

Tue 9/15

6:06 am-11:40 pm

1 stop20h 34m

$500
Quickest round-trip

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 10/22

8:21 pm-1:12 pm

1 stop13h 51m

Santo Domingo Las Americas

Thu 10/29

2:11 pm-11:40 pm

1 stop12h 29m

$523

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 5/9

2:15 pm-11:50 am

2 stops18h 35m

Santo Domingo Las Americas

Fri 5/22

6:50 pm-12:50 pm

2 stops21h 00m

$541

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Wed 5/27

2:15 pm-11:50 am

2 stops18h 35m

Santo Domingo Las Americas

Wed 6/3

6:50 pm-12:50 pm

2 stops21h 00m

$542

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 8/8

11:55 pm-5:55 pm

2 stops15h 00m

Santo Domingo Las Americas

Sat 8/22

6:50 pm-12:50 pm

2 stops21h 00m

$550

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sun 5/10

2:15 pm-11:50 am

2 stops18h 35m

Santo Domingo Las Americas

Fri 5/29

6:50 pm-12:50 pm

2 stops21h 00m

$558

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 5/21

2:15 pm-11:50 am

2 stops18h 35m

Santo Domingo Las Americas

Mon 5/25

6:50 pm-12:50 pm

2 stops21h 00m

$560

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 5/9

9:33 pm-12:28 pm

1 stop11h 55m

Santo Domingo Las Americas

Fri 5/22

9:20 am-12:33 am

1 stop18h 13m

$566

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 8/8

11:55 pm-5:55 pm

2 stops15h 00m

Santo Domingo Las Americas

Sat 8/22

6:50 pm-12:50 pm

2 stops21h 00m

$568

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 10/13

2:15 pm-11:50 am

2 stops18h 35m

Santo Domingo Las Americas

Thu 10/29

5:45 pm-1:00 pm

2 stops22h 15m

$569

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from San Francisco to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in October, then you should wait until January to fly from San Francisco, when ticket prices are also cheap, with an average price of $550.

How far in advance should I book a flight from San Francisco to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $656 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from San Francisco for as low as $447 on momondo.

Can stopping save me money on San Francisco to Santo Domingo flights?

You could potentially save up to 10% on your flight if you consider stops on a San Francisco to Santo Domingo flight.

How have San Francisco to Santo Domingo flight prices changed over time?

As of April 2026, prices for San Francisco to Santo Domingo flights are approximately 13% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santo Domingo (SFO to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santo Domingo

Fastest flight time

8h 29m

Direct flights

None
The fastest flight from San Francisco to Santo Domingo takes 8h 29m
There are no direct flights from San Francisco to Santo Domingo. There are no popular flight routes from San Francisco to Santo Domingo.
Search flight deals

Frequently asked questions about flying from San Francisco to Santo Domingo

  • How far is San Francisco to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 3410.4 mi away from San Francisco. A reasonable flight in good conditions will take 8h 29m.

  • When did momondo last update prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

    Prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from San Francisco Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santo Domingo?

Best airlines flying from San Francisco to Santo Domingo

Compare and see reviews for airlines that fly from San Francisco to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $313Free CancellationRating
6.5
2,514 reviews
Search Avianca flights
Copa AirlinesPriceFrom $420Free CancellationRating
7.5
1,580 reviews
Search Copa Airlines flights
JetBluePriceFrom $433Free CancellationRating
7.1
2,968 reviews
Search JetBlue flights
DeltaPriceFrom $587Free CancellationRating
7.9
8,467 reviews
Search Delta flights
American AirlinesPriceFrom $617Free CancellationRating
7.1
11,679 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Santo Domingo for you.

Can I find flights from San Francisco to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santo Domingo?

Once you have performed a search for San Francisco to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from San Francisco are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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