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Cheap flights from San Francisco to Santo Domingo from $242

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santo Domingo departing on 9/8. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
8:21 pm - 4:14 pm
SFO
-
SDQ
16h 53m
1 stop
Copa Airlines Logo
12:12 pm - 11:40 pm
SDQ
-
SFO
14h 28m
1 stop
$530Copa Airlines
Sun, Oct 18 - Wed, Oct 21
Copa Airlines Logo
8:21 pm - 2:25 am
SFO
-
SDQ
27h 04m
1 stop
Copa Airlines Logo
12:12 pm - 11:40 pm
SDQ
-
SFO
14h 28m
1 stop
$550Copa Airlines
Sun, Oct 18 - Wed, Oct 21
Avianca Logo
11:55 pm - 5:55 pm
SFO
-
SDQ
15h 00m
2 stops
Avianca Logo
6:50 pm - 12:50 pm
SDQ
-
SFO
21h 00m
2 stops
$552Avianca
Thu, Sep 3 - Sun, Sep 6
Copa Airlines Logo
7:36 pm - 4:12 pm
SFO
-
SDQ
16h 36m
1 stop
Copa Airlines Logo
8:55 am - 5:25 pm
SDQ
-
SFO
12h 30m
1 stop
$553Copa Airlines
Wed, Nov 11 - Sun, Nov 15
Copa Airlines Logo
8:21 pm - 10:56 pm
SFO
-
SDQ
23h 35m
1 stop
Copa Airlines Logo
2:16 pm - 11:40 pm
SDQ
-
SFO
12h 24m
1 stop
$573Copa Airlines
Thu, Sep 10 - Thu, Sep 24
Avianca Logo
2:15 pm - 5:55 pm
SFO
-
SDQ
24h 40m
2 stops
Avianca Logo
12:45 pm - 10:35 pm
SDQ
-
SFO
36h 50m
2 stops
$575Avianca
Tue, Aug 4 - Wed, Aug 12
Copa Airlines Logo
7:36 pm - 4:12 pm
SFO
-
SDQ
16h 36m
1 stop
Copa Airlines Logo
5:55 am - 11:12 pm
SDQ
-
SFO
21h 17m
1 stop
$576Copa Airlines
Thu, Nov 12 - Sun, Nov 15
Avianca Logo
7:45 am - 5:55 pm
SFO
-
SDQ
31h 10m
3 stops
Avianca Logo
12:45 pm - 6:25 am
SDQ
-
SFO
44h 40m
3 stops
$587Avianca
Tue, Aug 18 - Tue, Aug 25
Copa Airlines Logo
7:36 pm - 1:10 pm
SFO
-
SDQ
13h 34m
1 stop
Copa Airlines Logo
12:06 pm - 11:15 pm
SDQ
-
SFO
15h 09m
1 stop
$590Copa Airlines
Thu, Nov 26 - Tue, Jan 26
Avianca Logo
2:30 am - 11:50 am
SFO
-
SDQ
30h 20m
2 stops
Avianca Logo
12:45 pm - 6:25 am
SDQ
-
SFO
44h 40m
3 stops
$592Avianca
Tue, Aug 11 - Sun, Aug 16

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Avianca flights from San Francisco to Santo Domingo

Our best Avianca deals on San Francisco to Santo Domingo flight tickets
Avianca
Sep 3
SFO11:55 pmSan Francisco
15h 00m
2 stops
SDQ5:55 pmSanto Domingo Las Americas
Sep 6
SDQ6:50 pmSanto Domingo Las Americas
21h 00m
2 stops
SFO12:50 pmSan Francisco
$552
Avianca
Aug 4
SFO2:15 pmSan Francisco
24h 40m
2 stops
SDQ5:55 pmSanto Domingo Las Americas
Aug 12
SDQ12:45 pmSanto Domingo Las Americas
36h 50m
2 stops
SFO10:35 pmSan Francisco
$575
Avianca
Aug 4
SFO2:15 pmSan Francisco
24h 40m
2 stops
SDQ5:55 pmSanto Domingo Las Americas
Aug 12
SDQ12:45 pmSanto Domingo Las Americas
36h 50m
2 stops
SFO10:35 pmSan Francisco
$587

JetBlue flights from San Francisco to Santo Domingo

Our best JetBlue deals on San Francisco to Santo Domingo flight tickets
JetBlue
Aug 24
SFO10:40 pmSan Francisco
10h 45m
1 stop
SDQ12:25 pmSanto Domingo Las Americas
Aug 27
SDQ4:44 pmSanto Domingo Las Americas
10h 07m
1 stop
SFO11:51 pmSan Francisco
$610
JetBlue
Sep 21
SFO11:59 pmSan Francisco
12h 53m
2 stops
SDQ3:52 pmSanto Domingo Las Americas
Sep 25
SDQ3:59 pmSanto Domingo Las Americas
20h 06m
1 stop
SFO9:05 amSan Francisco
$656
JetBlue
Aug 17
SFO10:40 pmSan Francisco
10h 45m
1 stop
SDQ12:25 pmSanto Domingo Las Americas
Aug 27
SDQ4:44 pmSanto Domingo Las Americas
10h 07m
1 stop
SFO11:51 pmSan Francisco
$671

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated July 22, 2026.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sun 10/18

8:21 pm-4:14 pm

1 stop16h 53m

Santo Domingo Las Americas

Wed 10/21

12:12 pm-11:40 pm

1 stop14h 28m

$530

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sun 10/18

8:21 pm-2:25 am

1 stop27h 04m

Santo Domingo Las Americas

Wed 10/21

12:12 pm-11:40 pm

1 stop14h 28m

$550

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 9/3

11:55 pm-5:55 pm

2 stops15h 00m

Santo Domingo Las Americas

Sun 9/6

6:50 pm-12:50 pm

2 stops21h 00m

$552

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Wed 11/11

7:36 pm-4:12 pm

1 stop16h 36m

Santo Domingo Las Americas

Sun 11/15

8:55 am-5:25 pm

1 stop12h 30m

$553

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 9/10

8:21 pm-10:56 pm

1 stop23h 35m

Santo Domingo Las Americas

Thu 9/24

2:16 pm-11:40 pm

1 stop12h 24m

$573

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 8/4

2:15 pm-5:55 pm

2 stops24h 40m

Santo Domingo Las Americas

Wed 8/12

12:45 pm-10:35 pm

2 stops36h 50m

$575

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 11/12

7:36 pm-4:12 pm

1 stop16h 36m

Santo Domingo Las Americas

Sun 11/15

5:55 am-11:12 pm

1 stop21h 17m

$576

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 8/18

7:45 am-5:55 pm

3 stops31h 10m

Santo Domingo Las Americas

Tue 8/25

12:45 pm-6:25 am

3 stops44h 40m

$587
Quickest round-trip

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 11/26

7:36 pm-1:10 pm

1 stop13h 34m

Santo Domingo Las Americas

Tue 1/26

12:06 pm-11:15 pm

1 stop15h 09m

$590

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 8/11

2:30 am-11:50 am

2 stops30h 20m

Santo Domingo Las Americas

Sun 8/16

12:45 pm-6:25 am

3 stops44h 40m

$592

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from San Francisco to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in October, then you should wait until January to fly from San Francisco, when ticket prices are also cheap, with an average price of $550.

How far in advance should I book a flight from San Francisco to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $671 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from San Francisco for as low as $453 on momondo.

Can stopping save me money on San Francisco to Santo Domingo flights?

You could potentially save up to 17% on your flight if you consider stops on a San Francisco to Santo Domingo flight.

How have San Francisco to Santo Domingo flight prices changed over time?

As of July 2026, prices for San Francisco to Santo Domingo flights are approximately 13% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santo Domingo (SFO to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santo Domingo

Fastest flight time

10h 00m

Direct flights

None
The fastest flight from San Francisco to Santo Domingo takes 10h 00m
There are no direct flights from San Francisco to Santo Domingo. There are no popular flight routes from San Francisco to Santo Domingo.
Search flight deals

Frequently asked questions about flying from San Francisco to Santo Domingo

  • How far is San Francisco to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 3410.4 mi away from San Francisco. A reasonable flight in good conditions will take 10h 00m.

  • When did momondo last update prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

    Prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from San Francisco Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santo Domingo?

Best airlines flying from San Francisco to Santo Domingo

Compare and see reviews for airlines that fly from San Francisco to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $313Free CancellationRating
6.5
2,522 reviews
Search Avianca flights
Copa AirlinesPriceFrom $420Free CancellationRating
7.6
1,563 reviews
Search Copa Airlines flights
JetBluePriceFrom $432Free CancellationRating
7.1
3,019 reviews
Search JetBlue flights
DeltaPriceFrom $587Free CancellationRating
7.8
8,477 reviews
Search Delta flights
American AirlinesPriceFrom $679Free CancellationRating
7.1
11,838 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Santo Domingo for you.

Can I find flights from San Francisco to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santo Domingo?

Once you have performed a search for San Francisco to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from San Francisco are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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