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Cheap flights from San Francisco to Santo Domingo from $182

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santo Domingo departing on 2/6. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
4:07 pm - 4:29 pmSFO-SDQ
20h 22m2 stops
Multiple Airlines Logo
4:39 pm - 1:18 pmSDQ-SFO
24h 39m1 stop
$436Multiple Airlines
Find Deal
jue., dic. 4 - jue., dic. 11
JetBlue Logo
8:26 am - 4:34 amSFO-SDQ
16h 08m1 stop
JetBlue Logo
6:00 am - 7:15 pmSDQ-SFO
17h 15m1 stop
$454JetBlue
Find Deal
vie., ene. 23 - mar., feb. 10
Multiple Airlines Logo
11:20 pm - 3:07 pmSFO-SDQ
11h 47m1 stop
Multiple Airlines Logo
4:40 pm - 7:48 amSDQ-SFO
19h 08m2 stops
$459Multiple Airlines
Find Deal
mié., ene. 14 - sáb., ene. 24
Frontier Logo
11:20 pm - 3:24 pmSFO-SDQ
12h 04m1 stop
Frontier Logo
10:56 am - 12:25 amSDQ-SFO
41h 29m2 stops
$460Frontier
Find Deal
mié., dic. 31 - sáb., ene. 10
Frontier Logo
11:20 pm - 3:07 pmSFO-SDQ
11h 47m1 stop
Frontier Logo
4:19 pm - 7:53 amSDQ-SFO
19h 34m2 stops
$462Frontier
Find Deal
mié., ene. 14 - dom., ene. 18
Multiple Airlines Logo
10:49 am - 9:45 pmSFO-SDQ
30h 56m2 stops
Multiple Airlines Logo
4:39 pm - 1:13 pmSDQ-SFO
24h 34m1 stop
$478Multiple Airlines
Find Deal
vie., dic. 5 - jue., dic. 18
Copa Airlines Logo
1:54 am - 4:14 pmSFO-SDQ
11h 20m1 stop
Copa Airlines Logo
6:00 am - 6:28 pmSDQ-SFO
15h 28m1 stop
$482Copa Airlines
Find Deal
lun., mar. 16 - jue., mar. 26
Copa Airlines Logo
12:42 am - 6:05 pmSFO-SDQ
13h 23m1 stop
Copa Airlines Logo
6:00 am - 11:20 pmSDQ-SFO
21h 20m1 stop
$498Copa Airlines
Find Deal
jue., ene. 22 - mar., feb. 10
Avianca Logo
1:20 pm - 4:50 pmSFO-SDQ
23h 30m2 stops
Avianca Logo
5:45 pm - 11:20 pmSDQ-SFO
33h 35m2 stops
$500Avianca
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vie., feb. 27 - vie., mar. 6
Avianca Logo
2:20 pm - 5:15 pmSFO-SDQ
23h 55m2 stops
Avianca Logo
11:45 am - 11:55 pmSDQ-SFO
15h 10m2 stops
$501Avianca
Find Deal
mar., abr. 7 - mar., abr. 14

Copa Airlines flights from San Francisco to Santo Domingo

Our best Copa Airlines deals on San Francisco to Santo Domingo flight tickets
Copa Airlines
Mar 16
SFO1:54 amSan Francisco
11h 20m
1 stop
SDQ4:14 pmSanto Domingo Las Americas
Mar 26
SDQ6:00 amSanto Domingo Las Americas
15h 28m
1 stop
SFO6:28 pmSan Francisco
$482
Find similar
Copa Airlines
Jan 22
SFO12:42 amSan Francisco
13h 23m
1 stop
SDQ6:05 pmSanto Domingo Las Americas
Feb 10
SDQ6:00 amSanto Domingo Las Americas
21h 20m
1 stop
SFO11:20 pmSan Francisco
$498
Find similar
Copa Airlines
Mar 3
SFO12:54 amSan Francisco
11h 20m
1 stop
SDQ4:14 pmSanto Domingo Las Americas
Mar 8
SDQ11:56 amSanto Domingo Las Americas
14h 44m
1 stop
SFO11:40 pmSan Francisco
$560
Find similar

Avianca flights from San Francisco to Santo Domingo

Our best Avianca deals on San Francisco to Santo Domingo flight tickets
Avianca
Feb 27
SFO1:20 pmSan Francisco
23h 30m
2 stops
SDQ4:50 pmSanto Domingo Las Americas
Mar 6
SDQ5:45 pmSanto Domingo Las Americas
33h 35m
2 stops
SFO11:20 pmSan Francisco
$500
Find similar
Avianca
Apr 7
SFO2:20 pmSan Francisco
23h 55m
2 stops
SDQ5:15 pmSanto Domingo Las Americas
Apr 14
SDQ11:45 amSanto Domingo Las Americas
15h 10m
2 stops
SFO11:55 pmSan Francisco
$501
Find similar
Avianca
Apr 7
SFO2:20 pmSan Francisco
23h 55m
2 stops
SDQ5:15 pmSanto Domingo Las Americas
Apr 13
SDQ11:45 amSanto Domingo Las Americas
27h 50m
2 stops
SFO12:35 pmSan Francisco
$509
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momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

jue. 12/4

4:07 pm-4:29 pm

2 stops20h 22m

Santo Domingo Las Americas

jue. 12/11

4:39 pm-1:18 pm

1 stop24h 39m

$436

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

vie. 1/23

8:26 am-4:34 am

1 stop16h 08m

Santo Domingo Las Americas

mar. 2/10

6:00 am-7:15 pm

1 stop17h 15m

$454

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

mié. 1/14

11:20 pm-3:07 pm

1 stop11h 47m

Santo Domingo Las Americas

sáb. 1/24

4:40 pm-7:48 am

2 stops19h 08m

$459

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

mié. 12/31

11:20 pm-3:24 pm

1 stop12h 04m

Santo Domingo Las Americas

sáb. 1/10

10:56 am-12:25 am

2 stops41h 29m

$460

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

mié. 1/14

11:20 pm-3:07 pm

1 stop11h 47m

Santo Domingo Las Americas

dom. 1/18

4:19 pm-7:53 am

2 stops19h 34m

$462

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

vie. 12/5

10:49 am-9:45 pm

2 stops30h 56m

Santo Domingo Las Americas

jue. 12/18

4:39 pm-1:13 pm

1 stop24h 34m

$478

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

lun. 3/16

1:54 am-4:14 pm

1 stop11h 20m

Santo Domingo Las Americas

jue. 3/26

6:00 am-6:28 pm

1 stop15h 28m

$482

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

jue. 1/22

12:42 am-6:05 pm

1 stop13h 23m

Santo Domingo Las Americas

mar. 2/10

6:00 am-11:20 pm

1 stop21h 20m

$498

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

vie. 2/27

1:20 pm-4:50 pm

2 stops23h 30m

Santo Domingo Las Americas

vie. 3/6

5:45 pm-11:20 pm

2 stops33h 35m

$500

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

mar. 4/7

2:20 pm-5:15 pm

2 stops23h 55m

Santo Domingo Las Americas

mar. 4/14

11:45 am-11:55 pm

2 stops15h 10m

$501

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from San Francisco to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in September, then you should wait until January to fly from San Francisco, when ticket prices are also cheap, with an average price of $598.

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Tuesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $621. The most expensive day to fly to Santo Domingo is Saturday, with ticket prices averaging around $753.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the afternoon when flights can be purchased for as low as $621. Try not to purchase tickets in the morning because they tend to be around $750. Of course, these prices can vary depending on the time of year and what airport you fly to.

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $670 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from San Francisco for as low as $580 on momondo.

Can stopping save me money on San Francisco to Santo Domingo flights?

You could potentially save up to 13% on your flight if you consider stops on a San Francisco to Santo Domingo flight.

How have San Francisco to Santo Domingo flight prices changed over time?

As of November 2025, prices for San Francisco to Santo Domingo flights are approximately 11% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santo Domingo (SFO to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santo Domingo

Direct flights

None
There are no direct flights from San Francisco to Santo Domingo. There are no popular flight routes from San Francisco to Santo Domingo.
Search flight deals

  • How far is San Francisco to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 3411.1 mi away from San Francisco. A reasonable flight in good conditions will take 10h 40m.

  • When did momondo last update prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

    Prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from San Francisco Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santo Domingo?

Best airlines flying from San Francisco to Santo Domingo

Compare and see reviews for airlines that fly from San Francisco to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
AeromexicoPriceFrom $378Free CancellationRating
7.4
1,672 reviews
Search Aeromexico flights
JetBluePriceFrom $453Free CancellationRating
7.2
2,907 reviews
Search JetBlue flights
AviancaPriceFrom $487Free CancellationRating
6.6
2,468 reviews
Search Avianca flights
Copa AirlinesPriceFrom $497Free CancellationRating
7.6
1,563 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $619Free CancellationRating
7.2
11,040 reviews
Search American Airlines flights
DeltaPriceFrom $637Free CancellationRating
7.9
8,001 reviews
Search Delta flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Santo Domingo for you.

Can I find flights from San Francisco to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santo Domingo?

Once you have performed a search for San Francisco to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from San Francisco are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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