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Cheap flights from San Francisco to Santo Domingo from $189

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santo Domingo departing on 2/17. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
12:42 am - 6:05 pm
SFO
-
SDQ
13h 23m1 stop
Copa Airlines Logo
2:11 pm - 11:20 pm
SDQ
-
SFO
13h 09m1 stop
$421Copa Airlines
Tue, Jan 27 - Wed, Feb 4
JetBlue Logo
8:26 am - 4:35 am
SFO
-
SDQ
16h 09m1 stop
JetBlue Logo
3:30 pm - 11:29 pm
SDQ
-
SFO
11h 59m1 stop
$433JetBlue
Mon, Feb 2 - Fri, Feb 6
JetBlue Logo
12:40 pm - 1:54 pm
SFO
-
SDQ
21h 14m1 stop
JetBlue Logo
10:05 am - 12:22 am
SDQ
-
SFO
18h 17m1 stop
$438JetBlue
Fri, Jan 30 - Tue, Feb 3
Multiple Airlines Logo
11:00 pm - 11:20 pm
SFO
-
SDQ
20h 20m2 stops
Multiple Airlines Logo
6:10 am - 10:01 pm
SDQ
-
SFO
19h 51m1 stop
$448Multiple Airlines
Sat, Feb 21 - Sat, Feb 28
Frontier Logo
7:15 pm - 11:26 am
SFO
-
SDQ
12h 11m2 stops
Frontier Logo
12:35 pm - 12:28 am
SDQ
-
SFO
15h 53m2 stops
$450Frontier
Wed, Feb 11 - Sun, Feb 15
Multiple Airlines Logo
1:20 pm - 4:50 pm
SFO
-
SDQ
23h 30m2 stops
Multiple Airlines Logo
6:01 am - 6:55 pm
SDQ
-
SFO
16h 54m1 stop
$451Multiple Airlines
Thu, Jan 22 - Fri, Jan 30
JetBlue Logo
12:20 pm - 4:36 am
SFO
-
SDQ
12h 16m1 stop
JetBlue Logo
7:30 am - 4:56 pm
SDQ
-
SFO
13h 26m1 stop
$455JetBlue
Sat, Feb 7 - Wed, Mar 4
Avianca Logo
11:10 pm - 4:50 pm
SFO
-
SDQ
13h 40m2 stops
Avianca Logo
12:20 pm - 1:00 pm
SDQ
-
SFO
27h 40m2 stops
$456Avianca
Sat, Mar 7 - Tue, Mar 10
JetBlue Logo
12:40 pm - 2:53 am
SFO
-
SDQ
10h 13m1 stop
JetBlue Logo
4:15 am - 2:12 pm
SDQ
-
SFO
13h 57m1 stop
$460JetBlue
Thu, Jan 22 - Thu, Jan 29
JetBlue Logo
12:20 pm - 4:35 am
SFO
-
SDQ
12h 15m1 stop
JetBlue Logo
3:23 pm - 11:59 pm
SDQ
-
SFO
12h 36m1 stop
$462JetBlue
Tue, Feb 3 - Thu, Feb 12

Avianca flights from San Francisco to Santo Domingo

Our best Avianca deals on San Francisco to Santo Domingo flight tickets
Avianca
Mar 7
SFO11:10 pmSan Francisco
13h 40m
2 stops
SDQ4:50 pmSanto Domingo Las Americas
Mar 10
SDQ12:20 pmSanto Domingo Las Americas
27h 40m
2 stops
SFO1:00 pmSan Francisco
$456
Avianca
Jan 28
SFO1:20 pmSan Francisco
23h 30m
2 stops
SDQ4:50 pmSanto Domingo Las Americas
Feb 2
SDQ5:45 pmSanto Domingo Las Americas
22h 15m
2 stops
SFO12:00 pmSan Francisco
$491
Avianca
Feb 3
SFO11:10 pmSan Francisco
13h 40m
2 stops
SDQ4:50 pmSanto Domingo Las Americas
Feb 12
SDQ12:20 pmSanto Domingo Las Americas
27h 40m
2 stops
SFO12:00 pmSan Francisco
$499

JetBlue flights from San Francisco to Santo Domingo

Our best JetBlue deals on San Francisco to Santo Domingo flight tickets
JetBlue
Feb 2
SFO8:26 amSan Francisco
16h 09m
1 stop
SDQ4:35 amSanto Domingo Las Americas
Feb 6
SDQ3:30 pmSanto Domingo Las Americas
11h 59m
1 stop
SFO11:29 pmSan Francisco
$433
JetBlue
Jan 30
SFO12:40 pmSan Francisco
21h 14m
1 stop
SDQ1:54 pmSanto Domingo Las Americas
Feb 3
SDQ10:05 amSanto Domingo Las Americas
18h 17m
1 stop
SFO12:22 amSan Francisco
$438
JetBlue
Feb 7
SFO12:20 pmSan Francisco
12h 16m
1 stop
SDQ4:36 amSanto Domingo Las Americas
Mar 4
SDQ7:30 amSanto Domingo Las Americas
13h 26m
1 stop
SFO4:56 pmSan Francisco
$455

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 1/27

12:42 am-6:05 pm

1 stop13h 23m

Santo Domingo Las Americas

Wed 2/4

2:11 pm-11:20 pm

1 stop13h 09m

$421

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Mon 2/2

8:26 am-4:35 am

1 stop16h 09m

Santo Domingo Las Americas

Fri 2/6

3:30 pm-11:29 pm

1 stop11h 59m

$433

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Fri 1/30

12:40 pm-1:54 pm

1 stop21h 14m

Santo Domingo Las Americas

Tue 2/3

10:05 am-12:22 am

1 stop18h 17m

$438

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 2/21

11:00 pm-11:20 pm

2 stops20h 20m

Santo Domingo Las Americas

Sat 2/28

6:10 am-10:01 pm

1 stop19h 51m

$448

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Wed 2/11

7:15 pm-11:26 am

2 stops12h 11m

Santo Domingo Las Americas

Sun 2/15

12:35 pm-12:28 am

2 stops15h 53m

$450

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 1/22

1:20 pm-4:50 pm

2 stops23h 30m

Santo Domingo Las Americas

Fri 1/30

6:01 am-6:55 pm

1 stop16h 54m

$451

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 2/7

12:20 pm-4:36 am

1 stop12h 16m

Santo Domingo Las Americas

Wed 3/4

7:30 am-4:56 pm

1 stop13h 26m

$455

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 3/7

11:10 pm-4:50 pm

2 stops13h 40m

Santo Domingo Las Americas

Tue 3/10

12:20 pm-1:00 pm

2 stops27h 40m

$456

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Thu 1/22

12:40 pm-2:53 am

1 stop10h 13m

Santo Domingo Las Americas

Thu 1/29

4:15 am-2:12 pm

1 stop13h 57m

$460

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 2/3

12:20 pm-4:35 am

1 stop12h 15m

Santo Domingo Las Americas

Thu 2/12

3:23 pm-11:59 pm

1 stop12h 36m

$462

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from San Francisco to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in October, then you should wait until January to fly from San Francisco, when ticket prices are also cheap, with an average price of $588.

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $644 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from San Francisco for as low as $575 on momondo.

Can stopping save me money on San Francisco to Santo Domingo flights?

You could potentially save up to 17% on your flight if you consider stops on a San Francisco to Santo Domingo flight.

How have San Francisco to Santo Domingo flight prices changed over time?

As of January 2026, prices for San Francisco to Santo Domingo flights are approximately 6% cheaper when compared to flights at the same time last year.

When to book flights from San Francisco to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santo Domingo (SFO to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santo Domingo

Fastest flight time

9h 25m

Direct flights

None
The fastest flight from San Francisco to Santo Domingo takes 9h 25m
There are no direct flights from San Francisco to Santo Domingo. There are no popular flight routes from San Francisco to Santo Domingo.
Search flight deals

  • How far is San Francisco to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 3411.1 mi away from San Francisco. A reasonable flight in good conditions will take 9h 25m.

  • When did momondo last update prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

    Prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from San Francisco Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santo Domingo?

Best airlines flying from San Francisco to Santo Domingo

Compare and see reviews for airlines that fly from San Francisco to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $453Free CancellationRating
7.2
2,891 reviews
Search JetBlue flights
AviancaPriceFrom $487Free CancellationRating
6.6
2,490 reviews
Search Avianca flights
Copa AirlinesPriceFrom $497Free CancellationRating
7.6
1,562 reviews
Search Copa Airlines flights
DeltaPriceFrom $600Free CancellationRating
7.9
8,032 reviews
Search Delta flights
American AirlinesPriceFrom $619Free CancellationRating
7.2
11,097 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Santo Domingo for you.

Can I find flights from San Francisco to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santo Domingo?

Once you have performed a search for San Francisco to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from San Francisco are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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