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Cheap flights from San Francisco to Santo Domingo from $257

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
12:42 am - 2:04 amSFO  San Francisco-SDQ Santo Domingo Las Americas
21h 22m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:05 pm - 11:17 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
15h 12m1 stop Panama City Tocumen Intl
$540Copa Airlines
Sun, Jan 31 - Wed, Feb 10
Copa Airlines Logo
7:36 pm - 2:04 amSFO  San Francisco-SDQ Santo Domingo Las Americas
26h 28m1 stop Panama City Tocumen Intl
Copa Airlines Logo
8:48 am - 5:25 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
12h 37m1 stop Panama City Tocumen Intl
$544Copa Airlines
Tue, Feb 2 - Tue, Mar 2
American Airlines Logo
12:04 pm - 10:05 amSFO  San Francisco-SDQ Santo Domingo Las Americas
18h 01m1 stop Miami
American Airlines Logo
11:09 am - 12:13 amSDQ  Santo Domingo Las Americas-SFO San Francisco
17h 04m1 stop Miami
$548American Airlines
Fri, Dec 4 - Sat, Dec 12
American Airlines Logo
9:35 pm - 3:58 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
14h 23m1 stop Miami
American Airlines Logo
11:09 am - 12:13 amSDQ  Santo Domingo Las Americas-SFO San Francisco
17h 04m1 stop Miami
$548American Airlines
Sat, Dec 5 - Sat, Dec 12
Multiple Airlines Logo
10:17 pm - 9:45 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
19h 28m2 stops Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
10:56 am - 11:17 amSDQ  Santo Domingo Las Americas-SFO San Francisco
28h 21m3 stops Miami Atlanta Hartsfield-Jackson Denver Intl
$635Multiple Airlines
Mon, Nov 9 - Mon, Nov 16
Multiple Airlines Logo
9:14 am - 9:45 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
32h 31m3 stops Los Angeles Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
10:56 am - 11:17 amSDQ  Santo Domingo Las Americas-SFO San Francisco
28h 21m3 stops Miami Atlanta Hartsfield-Jackson Denver Intl
$666Multiple Airlines
Mon, Nov 9 - Mon, Nov 16
Avianca Logo
2:15 pm - 11:50 amSFO  San Francisco-SDQ Santo Domingo Las Americas
18h 35m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
6:50 pm - 12:50 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
21h 00m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$720Avianca
Fri, Oct 16 - Mon, Oct 19
Avianca Logo
11:55 pm - 5:55 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
15h 00m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
6:50 pm - 12:50 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
21h 00m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$720Avianca
Thu, Oct 15 - Mon, Oct 19
JetBlue Logo
10:10 pm - 4:59 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
14h 49m1 stop Boston Logan Intl
JetBlue Logo
3:35 am - 1:44 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
14h 09m1 stop New York John F Kennedy Intl
$732JetBlue
Mon, Nov 9 - Mon, Dec 7
JetBlue Logo
12:14 pm - 2:50 amSFO  San Francisco-SDQ Santo Domingo Las Americas
10h 36m1 stop Boston Logan Intl
JetBlue Logo
6:03 am - 7:34 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
17h 31m1 stop New York John F Kennedy Intl
$752JetBlue
Mon, Nov 2 - Thu, Nov 5

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Copa Airlines flights from San Francisco to Santo Domingo

Our best Copa Airlines deals on San Francisco to Santo Domingo flight tickets
Copa Airlines
Jan 31
SFO12:42 amSan Francisco
21h 22m
1 stop
SDQ2:04 amSanto Domingo Las Americas
Feb 10
SDQ12:05 pmSanto Domingo Las Americas
15h 12m
1 stop
SFO11:17 pmSan Francisco
$540
Copa Airlines
Feb 2
SFO7:36 pmSan Francisco
26h 28m
1 stop
SDQ2:04 amSanto Domingo Las Americas
Mar 2
SDQ8:48 amSanto Domingo Las Americas
12h 37m
1 stop
SFO5:25 pmSan Francisco
$544
Copa Airlines
Dec 10
SFO7:36 pmSan Francisco
13h 38m
1 stop
SDQ1:14 pmSanto Domingo Las Americas
Feb 17
SDQ7:02 pmSanto Domingo Las Americas
26h 23m
1 stop
SFO5:25 pmSan Francisco
$723

American Airlines flights from San Francisco to Santo Domingo

Our best American Airlines deals on San Francisco to Santo Domingo flight tickets
American Airlines
Dec 4
SFO11:09 pmSan Francisco
10h 08m
1 stop
SDQ1:17 pmSanto Domingo Las Americas
Dec 12
SDQ3:55 pmSanto Domingo Las Americas
10h 59m
1 stop
SFO10:54 pmSan Francisco
$548
American Airlines
Dec 4
SFO12:04 pmSan Francisco
18h 01m
1 stop
SDQ10:05 amSanto Domingo Las Americas
Dec 12
SDQ6:00 amSanto Domingo Las Americas
13h 13m
2 stops
SFO3:13 pmSan Francisco
$553
American Airlines
Oct 28
SFO11:39 amSan Francisco
18h 43m
1 stop
SDQ9:22 amSanto Domingo Las Americas
Nov 2
SDQ6:00 amSanto Domingo Las Americas
13h 36m
2 stops
SFO3:36 pmSan Francisco
$558

momondo Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Sun 1/31

12:42 am-2:04 am

1 stop21h 22m

Santo Domingo Las Americas

Wed 2/10

12:05 pm-11:17 pm

1 stop15h 12m

$540

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Tue 2/2

7:36 pm-2:04 am

1 stop26h 28m

Santo Domingo Las Americas

Tue 3/2

8:48 am-5:25 pm

1 stop12h 37m

$544

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Fri 12/4

12:04 pm-10:05 am

1 stop18h 01m

Santo Domingo Las Americas

Sat 12/12

11:09 am-12:13 am

1 stop17h 04m

$548

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Sat 12/5

9:35 pm-3:58 pm

1 stop14h 23m

Santo Domingo Las Americas

Sat 12/12

11:09 am-12:13 am

1 stop17h 04m

$548

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Mon 11/9

10:17 pm-9:45 pm

2 stops19h 28m

Santo Domingo Las Americas

Mon 11/16

10:56 am-11:17 am

3 stops28h 21m

$635

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Mon 11/9

9:14 am-9:45 pm

3 stops32h 31m

Santo Domingo Las Americas

Mon 11/16

10:56 am-11:17 am

3 stops28h 21m

$666

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Fri 10/16

2:15 pm-11:50 am

2 stops18h 35m

Santo Domingo Las Americas

Mon 10/19

6:50 pm-12:50 pm

2 stops21h 00m

$720

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Thu 10/15

11:55 pm-5:55 pm

2 stops15h 00m

Santo Domingo Las Americas

Mon 10/19

6:50 pm-12:50 pm

2 stops21h 00m

$720

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Mon 11/9

10:10 pm-4:59 pm

1 stop14h 49m

Santo Domingo Las Americas

Mon 12/7

3:35 am-1:44 pm

1 stop14h 09m

$732
Quickest round-trip

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Mon 11/2

12:14 pm-2:50 am

1 stop10h 36m

Santo Domingo Las Americas

Thu 11/5

6:03 am-7:34 pm

1 stop17h 31m

$752

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from San Francisco to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Santo Domingo?

Prices are currently low for flights on this route.

Typical prices usually range from $612 to $953.
The lowest price recently found on this route was $540.

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in January, then you should wait until May to fly from San Francisco, when ticket prices are also cheap, with an average price of $553.

How far in advance should I book a flight from San Francisco to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $717 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from San Francisco for as low as $532 on momondo.

Can stopping save me money on San Francisco to Santo Domingo flights?

You could potentially save up to 5% on your flight if you consider stops on a San Francisco to Santo Domingo flight.

How have San Francisco to Santo Domingo flight prices changed over time?

As of September 2026, prices for San Francisco to Santo Domingo flights are approximately 8% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santo Domingo (SFO to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santo Domingo

Best Price Found

$257

Fastest flight time

13h 38m

Direct flights

None
The best one-way flight to Santo Domingo from San Francisco in the past 72 hours is $257. The best round-trip flight deal from San Francisco to Santo Domingo found on momondo in the last 72 hours is $540.
The fastest flight from San Francisco to Santo Domingo takes 13h 38m
There are no direct flights from San Francisco to Santo Domingo. There are no popular flight routes from San Francisco to Santo Domingo.
Search flight deals

Frequently asked questions about flying from San Francisco to Santo Domingo

  • How far is San Francisco to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 3410.4 mi away from San Francisco. A reasonable flight in good conditions will take 13h 38m.

  • When did momondo last update prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

    Prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from San Francisco Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santo Domingo?

Best airlines flying from San Francisco to Santo Domingo

Compare and see reviews for airlines that fly from San Francisco to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $420Free CancellationRating
7.6
1,543 reviews
Search Copa Airlines flights
JetBluePriceFrom $453Free CancellationRating
7.1
3,039 reviews
Search JetBlue flights
AviancaPriceFrom $542Free CancellationRating
6.5
2,555 reviews
Search Avianca flights
DeltaPriceFrom $587Free CancellationRating
7.8
8,606 reviews
Search Delta flights
American AirlinesPriceFrom $669Free CancellationRating
7.0
12,098 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Santo Domingo for you.

Can I find flights from San Francisco to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santo Domingo?

Once you have performed a search for San Francisco to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from San Francisco are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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