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Cheap flights from San Francisco to Santo Domingo from $290

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
11:00 pm - 5:50 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
14h 50m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
6:45 pm - 11:55 amSDQ  Santo Domingo Las Americas-SFO San Francisco
21h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$537Avianca
Fri, Feb 19 - Fri, Feb 26
Avianca Logo
1:15 pm - 11:50 amSFO  San Francisco-SDQ Santo Domingo Las Americas
18h 35m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
6:45 pm - 11:55 amSDQ  Santo Domingo Las Americas-SFO San Francisco
21h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$537Avianca
Mon, Jan 18 - Mon, Feb 1
Copa Airlines Logo
7:36 pm - 11:42 amSFO  San Francisco-SDQ Santo Domingo Las Americas
12h 06m1 stop Panama City Tocumen Intl
Copa Airlines Logo
7:02 pm - 5:25 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
26h 23m1 stop Panama City Tocumen Intl
$538Copa Airlines
Mon, Jan 18 - Mon, Feb 1
Copa Airlines Logo
7:36 pm - 2:04 amSFO  San Francisco-SDQ Santo Domingo Las Americas
26h 28m1 stop Panama City Tocumen Intl
Copa Airlines Logo
2:37 pm - 11:05 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
12h 28m1 stop Panama City Tocumen Intl
$544Copa Airlines
Sun, Feb 21 - Wed, Mar 10
Multiple Airlines Logo
10:17 pm - 9:45 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
19h 28m2 stops Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
5:02 pm - 12:20 amSDQ  Santo Domingo Las Americas-SFO San Francisco
35h 18m2 stops Miami Denver Intl
$621Multiple Airlines
Mon, Nov 2 - Thu, Nov 5
Multiple Airlines Logo
10:17 pm - 9:45 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
19h 28m2 stops Atlanta Hartsfield-Jackson Miami
Multiple Airlines Logo
5:02 pm - 11:04 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
34h 02m3 stops Miami Atlanta Hartsfield-Jackson Dallas/Fort Worth
$657Multiple Airlines
Mon, Nov 2 - Thu, Nov 5
JetBlue Logo
11:30 am - 1:46 amSFO  San Francisco-SDQ Santo Domingo Las Americas
10h 16m1 stop Fort Lauderdale
JetBlue Logo
2:32 pm - 10:30 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
11h 58m1 stop Fort Lauderdale
$686JetBlue
Sun, Nov 1 - Sat, Nov 7
JetBlue Logo
11:25 pm - 4:18 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
12h 53m1 stop Fort Lauderdale
JetBlue Logo
2:32 pm - 10:30 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
11h 58m1 stop Fort Lauderdale
$686JetBlue
Mon, Nov 2 - Tue, Nov 10
American Airlines Logo
10:58 pm - 1:55 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
10h 57m1 stop Philadelphia
American Airlines Logo
3:55 pm - 10:47 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
10h 52m1 stop Miami
$715American Airlines
Mon, Nov 2 - Thu, Nov 5
American Airlines Logo
11:53 pm - 3:51 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
11h 58m1 stop Miami
American Airlines Logo
2:22 pm - 10:17 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
11h 55m1 stop Philadelphia
$722American Airlines
Tue, Nov 24 - Wed, Dec 2

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Avianca flights from San Francisco to Santo Domingo

Our best Avianca deals on San Francisco to Santo Domingo flight tickets
Avianca
Jan 18
SFO1:15 pmSan Francisco
18h 35m
2 stops
SDQ11:50 amSanto Domingo Las Americas
Feb 1
SDQ6:45 pmSanto Domingo Las Americas
21h 10m
2 stops
SFO11:55 amSan Francisco
$537
Avianca
Jan 18
SFO1:15 pmSan Francisco
24h 35m
2 stops
SDQ5:50 pmSanto Domingo Las Americas
Feb 1
SDQ12:45 pmSanto Domingo Las Americas
27h 10m
2 stops
SFO11:55 amSan Francisco
$571
Avianca
Nov 11
SFO1:15 pmSan Francisco
24h 35m
2 stops
SDQ5:50 pmSanto Domingo Las Americas
Nov 15
SDQ6:45 pmSanto Domingo Las Americas
45h 10m
2 stops
SFO11:55 amSan Francisco
$581

Copa Airlines flights from San Francisco to Santo Domingo

Our best Copa Airlines deals on San Francisco to Santo Domingo flight tickets
Copa Airlines
Jan 18
SFO7:36 pmSan Francisco
12h 06m
1 stop
SDQ11:42 amSanto Domingo Las Americas
Feb 1
SDQ7:02 pmSanto Domingo Las Americas
26h 23m
1 stop
SFO5:25 pmSan Francisco
$538
Copa Airlines
Feb 21
SFO7:36 pmSan Francisco
26h 28m
1 stop
SDQ2:04 amSanto Domingo Las Americas
Mar 10
SDQ2:37 pmSanto Domingo Las Americas
12h 28m
1 stop
SFO11:05 pmSan Francisco
$544
Copa Airlines
Jan 17
SFO12:40 amSan Francisco
21h 24m
1 stop
SDQ2:04 amSanto Domingo Las Americas
Feb 1
SDQ7:02 pmSanto Domingo Las Americas
26h 23m
1 stop
SFO5:25 pmSan Francisco
$567

momondo Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Fri 2/19

11:00 pm-5:50 pm

2 stops14h 50m

Santo Domingo Las Americas

Fri 2/26

6:45 pm-11:55 am

2 stops21h 10m

$537

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Mon 1/18

1:15 pm-11:50 am

2 stops18h 35m

Santo Domingo Las Americas

Mon 2/1

6:45 pm-11:55 am

2 stops21h 10m

$537

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Mon 1/18

7:36 pm-11:42 am

1 stop12h 06m

Santo Domingo Las Americas

Mon 2/1

7:02 pm-5:25 pm

1 stop26h 23m

$538

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Sun 2/21

7:36 pm-2:04 am

1 stop26h 28m

Santo Domingo Las Americas

Wed 3/10

2:37 pm-11:05 pm

1 stop12h 28m

$544

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Mon 11/2

10:17 pm-9:45 pm

2 stops19h 28m

Santo Domingo Las Americas

Thu 11/5

5:02 pm-12:20 am

2 stops35h 18m

$621

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Mon 11/2

10:17 pm-9:45 pm

2 stops19h 28m

Santo Domingo Las Americas

Thu 11/5

5:02 pm-11:04 pm

3 stops34h 02m

$657

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Sun 11/1

11:30 am-1:46 am

1 stop10h 16m

Santo Domingo Las Americas

Sat 11/7

2:32 pm-10:30 pm

1 stop11h 58m

$686

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Mon 11/2

11:25 pm-4:18 pm

1 stop12h 53m

Santo Domingo Las Americas

Tue 11/10

2:32 pm-10:30 pm

1 stop11h 58m

$686
Quickest round-trip

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Mon 11/2

10:58 pm-1:55 pm

1 stop10h 57m

Santo Domingo Las Americas

Thu 11/5

3:55 pm-10:47 pm

1 stop10h 52m

$715

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Tue 11/24

11:53 pm-3:51 pm

1 stop11h 58m

Santo Domingo Las Americas

Wed 12/2

2:22 pm-10:17 pm

1 stop11h 55m

$722

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from San Francisco to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Santo Domingo?

Prices are currently low for flights on this route.

Typical prices usually range from $596 to $880.
The lowest price recently found on this route was $581.

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in January, then you should wait until May to fly from San Francisco, when ticket prices are also cheap, with an average price of $553.

How far in advance should I book a flight from San Francisco to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $721 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from San Francisco for as low as $532 on momondo.

Can stopping save me money on San Francisco to Santo Domingo flights?

You could potentially save up to 2% on your flight if you consider stops on a San Francisco to Santo Domingo flight.

How have San Francisco to Santo Domingo flight prices changed over time?

As of October 2026, prices for San Francisco to Santo Domingo flights are approximately 24% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santo Domingo (SFO to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santo Domingo

Best Price Found

$290

Fastest flight time

9h 37m

Direct flights

None
The best one-way flight to Santo Domingo from San Francisco in the past 72 hours is $290. The best round-trip flight deal from San Francisco to Santo Domingo found on momondo in the last 72 hours is $537.
The fastest flight from San Francisco to Santo Domingo takes 9h 37m
There are no direct flights from San Francisco to Santo Domingo. There are no popular flight routes from San Francisco to Santo Domingo.
Search flight deals

Frequently asked questions about flying from San Francisco to Santo Domingo

  • How far is San Francisco to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 3410.4 mi away from San Francisco. A reasonable flight in good conditions will take 9h 37m.

  • When did momondo last update prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

    Prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from San Francisco Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santo Domingo?

Best airlines flying from San Francisco to Santo Domingo

Compare and see reviews for airlines that fly from San Francisco to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $420Free CancellationRating
7.6
1,549 reviews
Search Copa Airlines flights
JetBluePriceFrom $453Free CancellationRating
7.1
3,054 reviews
Search JetBlue flights
AviancaPriceFrom $542Free CancellationRating
6.5
2,553 reviews
Search Avianca flights
DeltaPriceFrom $587Free CancellationRating
7.8
8,651 reviews
Search Delta flights
American AirlinesPriceFrom $669Free CancellationRating
7.0
12,168 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Santo Domingo for you.

Can I find flights from San Francisco to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santo Domingo?

Once you have performed a search for San Francisco to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from San Francisco are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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