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Cheap flights from San Francisco to Santo Domingo from $274

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
7:36 pm - 10:54 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
23h 18m1 stop Panama City Tocumen Intl
Copa Airlines Logo
5:50 am - 5:25 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
15h 35m1 stop Panama City Tocumen Intl
$536Copa Airlines
Tue, Jan 19 - Tue, Jan 26
Avianca Logo
11:00 pm - 5:50 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
14h 50m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
6:45 pm - 11:55 amSDQ  Santo Domingo Las Americas-SFO San Francisco
21h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$537Avianca
Fri, Feb 19 - Sat, Feb 27
Avianca Logo
11:00 pm - 5:50 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
14h 50m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
6:45 pm - 11:55 amSDQ  Santo Domingo Las Americas-SFO San Francisco
21h 10m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$537Avianca
Fri, Feb 19 - Fri, Feb 26
Copa Airlines Logo
7:36 pm - 1:06 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
13h 30m1 stop Panama City Tocumen Intl
Copa Airlines Logo
5:53 am - 5:25 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
15h 32m1 stop Panama City Tocumen Intl
$554Copa Airlines
Tue, Feb 16 - Tue, Feb 23
Multiple Airlines Logo
7:14 pm - 11:12 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
23h 58m3 stops Las Vegas Harry Reid Intl Cleveland Hopkins Intl Miami
Multiple Airlines Logo
3:35 pm - 9:44 amSDQ  Santo Domingo Las Americas-SFO San Francisco
22h 09m3 stops Miami Atlanta Hartsfield-Jackson Denver Intl
$626Multiple Airlines
Wed, Nov 18 - Tue, Dec 1
Multiple Airlines Logo
6:02 am - 9:19 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
35h 17m2 stops Denver Intl Miami
Multiple Airlines Logo
3:35 pm - 7:49 amSDQ  Santo Domingo Las Americas-SFO San Francisco
20h 14m2 stops Miami Las Vegas Harry Reid Intl
$639Multiple Airlines
Sat, Nov 14 - Sat, Nov 21
American Airlines Logo
11:09 pm - 1:17 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
10h 08m1 stop Philadelphia
American Airlines Logo
3:55 pm - 10:54 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
10h 59m1 stop Miami
$722American Airlines
Fri, Dec 4 - Sat, Dec 12
American Airlines Logo
9:35 pm - 10:05 amSFO  San Francisco-SDQ Santo Domingo Las Americas
8h 30m1 stop Miami
American Airlines Logo
6:00 am - 7:20 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
17h 20m1 stop Miami
$722American Airlines
Sat, Dec 5 - Sat, Dec 12
JetBlue Logo
11:25 pm - 4:18 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
12h 53m1 stop Fort Lauderdale
JetBlue Logo
5:01 am - 12:09 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
11h 08m1 stop Fort Lauderdale
$739JetBlue
Mon, Nov 16 - Mon, Nov 23
JetBlue Logo
11:25 pm - 1:22 pmSFO  San Francisco-SDQ Santo Domingo Las Americas
9h 57m1 stop Fort Lauderdale
JetBlue Logo
3:04 pm - 11:48 pmSDQ  Santo Domingo Las Americas-SFO San Francisco
12h 44m1 stop Fort Lauderdale
$742JetBlue
Mon, Nov 16 - Tue, Nov 24

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Copa Airlines flights from San Francisco to Santo Domingo

Our best Copa Airlines deals on San Francisco to Santo Domingo flight tickets
Copa Airlines
Jan 19
SFO7:36 pmSan Francisco
23h 18m
1 stop
SDQ10:54 pmSanto Domingo Las Americas
Jan 26
SDQ5:50 amSanto Domingo Las Americas
15h 35m
1 stop
SFO5:25 pmSan Francisco
$536
Copa Airlines
Feb 16
SFO7:36 pmSan Francisco
13h 30m
1 stop
SDQ1:06 pmSanto Domingo Las Americas
Feb 23
SDQ5:53 amSanto Domingo Las Americas
15h 32m
1 stop
SFO5:25 pmSan Francisco
$554
Copa Airlines
Jan 31
SFO12:42 amSan Francisco
21h 22m
1 stop
SDQ2:04 amSanto Domingo Las Americas
Feb 5
SDQ7:02 pmSanto Domingo Las Americas
26h 23m
1 stop
SFO5:25 pmSan Francisco
$572

American Airlines flights from San Francisco to Santo Domingo

Our best American Airlines deals on San Francisco to Santo Domingo flight tickets
American Airlines
Nov 6
SFO9:35 pmSan Francisco
13h 20m
1 stop
SDQ2:55 pmSanto Domingo Las Americas
Nov 11
SDQ7:00 amSanto Domingo Las Americas
19h 47m
1 stop
SFO10:47 pmSan Francisco
$722
American Airlines
Nov 6
SFO9:35 pmSan Francisco
8h 44m
1 stop
SDQ10:19 amSanto Domingo Las Americas
Nov 11
SDQ12:59 pmSanto Domingo Las Americas
15h 40m
2 stops
SFO12:39 amSan Francisco
$727
American Airlines
Jan 11
SFO11:59 pmSan Francisco
18h 05m
1 stop
SDQ10:04 pmSanto Domingo Las Americas
Jan 15
SDQ12:41 pmSanto Domingo Las Americas
14h 22m
1 stop
SFO11:03 pmSan Francisco
$728

momondo Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Tue 1/19

7:36 pm-10:54 pm

1 stop23h 18m

Santo Domingo Las Americas

Tue 1/26

5:50 am-5:25 pm

1 stop15h 35m

$536

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Fri 2/19

11:00 pm-5:50 pm

2 stops14h 50m

Santo Domingo Las Americas

Sat 2/27

6:45 pm-11:55 am

2 stops21h 10m

$537

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Fri 2/19

11:00 pm-5:50 pm

2 stops14h 50m

Santo Domingo Las Americas

Fri 2/26

6:45 pm-11:55 am

2 stops21h 10m

$537

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Tue 2/16

7:36 pm-1:06 pm

1 stop13h 30m

Santo Domingo Las Americas

Tue 2/23

5:53 am-5:25 pm

1 stop15h 32m

$554

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Wed 11/18

7:14 pm-11:12 pm

3 stops23h 58m

Santo Domingo Las Americas

Tue 12/1

3:35 pm-9:44 am

3 stops22h 09m

$626

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Sat 11/14

6:02 am-9:19 pm

2 stops35h 17m

Santo Domingo Las Americas

Sat 11/21

3:35 pm-7:49 am

2 stops20h 14m

$639
Quickest round-trip

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Fri 12/4

11:09 pm-1:17 pm

1 stop10h 08m

Santo Domingo Las Americas

Sat 12/12

3:55 pm-10:54 pm

1 stop10h 59m

$722

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Sat 12/5

9:35 pm-10:05 am

1 stop8h 30m

Santo Domingo Las Americas

Sat 12/12

6:00 am-7:20 pm

1 stop17h 20m

$722

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Mon 11/16

11:25 pm-4:18 pm

1 stop12h 53m

Santo Domingo Las Americas

Mon 11/23

5:01 am-12:09 pm

1 stop11h 08m

$739

San FranciscoSanto Domingo

SFO San Francisco - SDQ Santo Domingo Las Americas

SFOSDQ

San Francisco

Mon 11/16

11:25 pm-1:22 pm

1 stop9h 57m

Santo Domingo Las Americas

Tue 11/24

3:04 pm-11:48 pm

1 stop12h 44m

$742

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from San Francisco to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Santo Domingo?

Prices are currently low for flights on this route.

Typical prices usually range from $580 to $849.
The lowest price recently found on this route was $536.

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in January, then you should wait until May to fly from San Francisco, when ticket prices are also cheap, with an average price of $553.

How far in advance should I book a flight from San Francisco to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $726 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from San Francisco for as low as $532 on momondo.

Can stopping save me money on San Francisco to Santo Domingo flights?

You could potentially save up to 2% on your flight if you consider stops on a San Francisco to Santo Domingo flight.

How have San Francisco to Santo Domingo flight prices changed over time?

As of October 2026, prices for San Francisco to Santo Domingo flights are approximately 37% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santo Domingo (SFO to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santo Domingo

Best Price Found

$274

Fastest flight time

9h 57m

Direct flights

None
The best one-way flight to Santo Domingo from San Francisco in the past 72 hours is $274. The best round-trip flight deal from San Francisco to Santo Domingo found on momondo in the last 72 hours is $536.
The fastest flight from San Francisco to Santo Domingo takes 9h 57m
There are no direct flights from San Francisco to Santo Domingo. There are no popular flight routes from San Francisco to Santo Domingo.
Search flight deals

Frequently asked questions about flying from San Francisco to Santo Domingo

  • How far is San Francisco to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 3410.4 mi away from San Francisco. A reasonable flight in good conditions will take 9h 57m.

  • When did momondo last update prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

    Prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from San Francisco Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santo Domingo?

Best airlines flying from San Francisco to Santo Domingo

Compare and see reviews for airlines that fly from San Francisco to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $420Free CancellationRating
7.6
1,559 reviews
Search Copa Airlines flights
JetBluePriceFrom $433Free CancellationRating
7.1
3,059 reviews
Search JetBlue flights
AviancaPriceFrom $542Free CancellationRating
6.5
2,552 reviews
Search Avianca flights
DeltaPriceFrom $587Free CancellationRating
7.8
8,661 reviews
Search Delta flights
American AirlinesPriceFrom $682Free CancellationRating
7.0
12,185 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Santo Domingo for you.

Can I find flights from San Francisco to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santo Domingo?

Once you have performed a search for San Francisco to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from San Francisco are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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