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Cheap flights from San Francisco to Santo Domingo from $197

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Santo Domingo departing on 3/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Frontier Logo
8:58 am - 9:39 am
SFO
-
SDQ
20h 41m
2 stops
Frontier Logo
11:56 am - 9:38 pm
SDQ
-
SFO
13h 42m
2 stops
$404Frontier
Sat, Feb 21 - Sat, Mar 7
Frontier Logo
7:20 am - 11:26 am
SFO
-
SDQ
24h 06m
2 stops
Frontier Logo
11:56 am - 9:38 pm
SDQ
-
SFO
13h 42m
2 stops
$419Frontier
Wed, Feb 25 - Sat, Mar 7
JetBlue Logo
10:39 pm - 2:13 pm
SFO
-
SDQ
11h 34m
1 stop
JetBlue Logo
6:20 am - 4:56 pm
SDQ
-
SFO
14h 36m
1 stop
$433JetBlue
Sat, Feb 21 - Wed, Mar 4
JetBlue Logo
11:59 pm - 2:14 pm
SFO
-
SDQ
10h 15m
1 stop
JetBlue Logo
6:01 am - 6:55 pm
SDQ
-
SFO
16h 54m
1 stop
$434JetBlue
Sat, Jan 31 - Tue, Feb 3
Multiple Airlines Logo
10:58 pm - 4:29 pm
SFO
-
SDQ
13h 31m
2 stops
Multiple Airlines Logo
1:11 pm - 11:28 pm
SDQ
-
SFO
14h 17m
1 stop
$436Multiple Airlines
Tue, Feb 24 - Tue, Mar 3
Copa Airlines Logo
12:42 am - 10:39 pm
SFO
-
SDQ
17h 57m
1 stop
Copa Airlines Logo
8:50 am - 11:20 pm
SDQ
-
SFO
18h 30m
1 stop
$441Copa Airlines
Mon, Feb 2 - Sat, Feb 7
JetBlue Logo
11:59 pm - 2:14 pm
SFO
-
SDQ
10h 15m
1 stop
JetBlue Logo
3:28 pm - 11:59 pm
SDQ
-
SFO
12h 31m
1 stop
$444JetBlue
Sun, Feb 1 - Wed, Feb 25
JetBlue Logo
8:00 am - 2:55 am
SFO
-
SDQ
14h 55m
1 stop
JetBlue Logo
2:28 pm - 9:29 am
SDQ
-
SFO
22h 01m
1 stop
$446JetBlue
Mon, Feb 23 - Sun, Mar 8
Multiple Airlines Logo
10:58 pm - 4:29 pm
SFO
-
SDQ
13h 31m
2 stops
Multiple Airlines Logo
12:31 pm - 11:28 pm
SDQ
-
SFO
14h 57m
1 stop
$453Multiple Airlines
Tue, Feb 24 - Thu, Mar 5
Multiple Airlines Logo
10:58 pm - 2:20 pm
SFO
-
SDQ
35h 22m
2 stops
Multiple Airlines Logo
1:11 pm - 11:28 pm
SDQ
-
SFO
14h 17m
1 stop
$456Multiple Airlines
Wed, Feb 25 - Tue, Mar 3

Frontier flights from San Francisco to Santo Domingo

Our best Frontier deals on San Francisco to Santo Domingo flight tickets
Frontier
Feb 21
SFO8:58 amSan Francisco
20h 41m
2 stops
SDQ9:39 amSanto Domingo Las Americas
Mar 7
SDQ11:56 amSanto Domingo Las Americas
13h 42m
2 stops
SFO9:38 pmSan Francisco
$404
Frontier
Feb 25
SFO7:20 amSan Francisco
24h 06m
2 stops
SDQ11:26 amSanto Domingo Las Americas
Mar 7
SDQ11:56 amSanto Domingo Las Americas
13h 42m
2 stops
SFO9:38 pmSan Francisco
$419
Frontier
Feb 20
SFO10:28 amSan Francisco
22h 42m
2 stops
SDQ1:10 pmSanto Domingo Las Americas
Mar 7
SDQ11:56 amSanto Domingo Las Americas
13h 42m
2 stops
SFO9:38 pmSan Francisco
$459

JetBlue flights from San Francisco to Santo Domingo

Our best JetBlue deals on San Francisco to Santo Domingo flight tickets
JetBlue
Feb 21
SFO10:39 pmSan Francisco
11h 34m
1 stop
SDQ2:13 pmSanto Domingo Las Americas
Mar 2
SDQ3:28 pmSanto Domingo Las Americas
12h 31m
1 stop
SFO11:59 pmSan Francisco
$433
JetBlue
Jan 31
SFO11:59 pmSan Francisco
10h 15m
1 stop
SDQ2:14 pmSanto Domingo Las Americas
Feb 3
SDQ6:01 amSanto Domingo Las Americas
16h 54m
1 stop
SFO6:55 pmSan Francisco
$434
JetBlue
Feb 1
SFO11:59 pmSan Francisco
10h 15m
1 stop
SDQ2:14 pmSanto Domingo Las Americas
Feb 25
SDQ3:28 pmSanto Domingo Las Americas
12h 31m
1 stop
SFO11:59 pmSan Francisco
$444

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from San Francisco to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 2/21

8:58 am-9:39 am

2 stops20h 41m

Santo Domingo Las Americas

Sat 3/7

11:56 am-9:38 pm

2 stops13h 42m

$404

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Wed 2/25

7:20 am-11:26 am

2 stops24h 06m

Santo Domingo Las Americas

Sat 3/7

11:56 am-9:38 pm

2 stops13h 42m

$419

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 2/21

10:39 pm-2:13 pm

1 stop11h 34m

Santo Domingo Las Americas

Wed 3/4

6:20 am-4:56 pm

1 stop14h 36m

$433

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sat 1/31

11:59 pm-2:14 pm

1 stop10h 15m

Santo Domingo Las Americas

Tue 2/3

6:01 am-6:55 pm

1 stop16h 54m

$434

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 2/24

10:58 pm-4:29 pm

2 stops13h 31m

Santo Domingo Las Americas

Tue 3/3

1:11 pm-11:28 pm

1 stop14h 17m

$436

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Mon 2/2

12:42 am-10:39 pm

1 stop17h 57m

Santo Domingo Las Americas

Sat 2/7

8:50 am-11:20 pm

1 stop18h 30m

$441

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Sun 2/1

11:59 pm-2:14 pm

1 stop10h 15m

Santo Domingo Las Americas

Wed 2/25

3:28 pm-11:59 pm

1 stop12h 31m

$444

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Mon 2/23

8:00 am-2:55 am

1 stop14h 55m

Santo Domingo Las Americas

Sun 3/8

2:28 pm-9:29 am

1 stop22h 01m

$446

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Tue 2/24

10:58 pm-4:29 pm

2 stops13h 31m

Santo Domingo Las Americas

Thu 3/5

12:31 pm-11:28 pm

1 stop14h 57m

$453

San FranciscoSanto Domingo

SFO - SDQ

SFOSDQ

San Francisco

Wed 2/25

10:58 pm-2:20 pm

2 stops35h 22m

Santo Domingo Las Americas

Tue 3/3

1:11 pm-11:28 pm

1 stop14h 17m

$456

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from San Francisco to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in October, then you should wait until January to fly from San Francisco, when ticket prices are also cheap, with an average price of $588.

How far in advance should I book a flight to Santo Domingo?

You are more likely to see cheaper flights to Santo Domingo from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Santo Domingo for around $643 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santo Domingo from San Francisco for as low as $575 on momondo.

Can stopping save me money on San Francisco to Santo Domingo flights?

You could potentially save up to 17% on your flight if you consider stops on a San Francisco to Santo Domingo flight.

How have San Francisco to Santo Domingo flight prices changed over time?

As of January 2026, prices for San Francisco to Santo Domingo flights are approximately 6% cheaper when compared to flights at the same time last year.

When to book flights from San Francisco to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Santo Domingo (SFO to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Santo Domingo

Fastest flight time

9h 25m

Direct flights

None
The fastest flight from San Francisco to Santo Domingo takes 9h 25m
There are no direct flights from San Francisco to Santo Domingo. There are no popular flight routes from San Francisco to Santo Domingo.
Search flight deals

  • How far is San Francisco to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 3411.1 mi away from San Francisco. A reasonable flight in good conditions will take 9h 25m.

  • When did momondo last update prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

    Prices for flights from San Francisco Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from San Francisco Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from San Francisco Airport to Santo Domingo Las Americas Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from San Francisco Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The necessary travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from San Francisco to Santo Domingo?

Best airlines flying from San Francisco to Santo Domingo

Compare and see reviews for airlines that fly from San Francisco to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $313Free CancellationRating
6.6
2,492 reviews
Search Avianca flights
JetBluePriceFrom $453Free CancellationRating
7.2
2,887 reviews
Search JetBlue flights
Copa AirlinesPriceFrom $497Free CancellationRating
7.6
1,559 reviews
Search Copa Airlines flights
DeltaPriceFrom $587Free CancellationRating
7.9
8,048 reviews
Search Delta flights
American AirlinesPriceFrom $619Free CancellationRating
7.2
11,129 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Santo Domingo?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Santo Domingo for you.

Can I find flights from San Francisco to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from San Francisco on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from San Francisco to Santo Domingo?

Once you have performed a search for San Francisco to Santo Domingo flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from San Francisco are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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