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Cheap flights from San Francisco to Guayaquil from $367

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Guayaquil departing on 1/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from San Francisco to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
1:20 pm - 9:15 am
SFO
-
GYE
16h 55m2 stops
Avianca Logo
10:25 am - 11:20 pm
GYE
-
SFO
15h 55m2 stops
$367Avianca
Fri, Jan 16 - Thu, Jan 29
Copa Airlines Logo
12:42 am - 11:42 pm
SFO
-
GYE
20h 00m1 stop
Copa Airlines Logo
8:34 am - 11:20 pm
GYE
-
SFO
17h 46m1 stop
$386Copa Airlines
Sun, Jan 18 - Mon, Feb 2
Avianca Logo
2:20 pm - 8:45 am
SFO
-
GYE
16h 25m2 stops
Avianca Logo
9:45 am - 11:55 pm
GYE
-
SFO
16h 10m2 stops
$387Avianca
Sat, Apr 11 - Sat, Apr 18
Avianca Logo
1:20 pm - 9:15 am
SFO
-
GYE
16h 55m2 stops
Avianca Logo
6:55 pm - 12:00 pm
GYE
-
SFO
20h 05m2 stops
$395Avianca
Mon, Jan 19 - Mon, Feb 2
Copa Airlines Logo
12:42 am - 11:18 am
SFO
-
GYE
31h 36m1 stop
Copa Airlines Logo
6:33 pm - 11:20 pm
GYE
-
SFO
31h 47m1 stop
$432Copa Airlines
Thu, Jan 29 - Fri, Feb 6
Multiple Airlines Logo
11:20 pm - 12:21 am
SFO
-
GYE
22h 01m2 stops
Multiple Airlines Logo
2:35 pm - 11:20 pm
GYE
-
SFO
11h 45m1 stop
$443Multiple Airlines
Fri, Jan 16 - Thu, Jan 29
Multiple Airlines Logo
11:10 pm - 5:45 pm
SFO
-
GYE
15h 35m2 stops
Multiple Airlines Logo
4:45 pm - 10:31 am
GYE
-
SFO
20h 46m1 stop
$445Multiple Airlines
Fri, Jan 30 - Fri, Feb 6
Avianca Logo
1:20 pm - 9:15 am
SFO
-
GYE
16h 55m2 stops
Avianca Logo
6:55 pm - 12:00 pm
GYE
-
SFO
20h 05m2 stops
$485Avianca
Fri, Jan 16 - Thu, Jan 29
American Airlines Logo
10:59 pm - 11:22 pm
SFO
-
GYE
21h 23m1 stop
American Airlines Logo
7:15 am - 11:12 pm
GYE
-
SFO
18h 57m2 stops
$498American Airlines
Mon, Jan 19 - Mon, Feb 2
JetBlue Logo
11:59 pm - 3:35 pm
SFO
-
GYE
12h 36m1 stop
JetBlue Logo
7:45 am - 12:22 am
GYE
-
SFO
19h 37m1 stop
$521JetBlue
Fri, Jan 16 - Thu, Jan 29

Avianca flights from San Francisco to Guayaquil

Our best Avianca deals on San Francisco to Guayaquil flight tickets
Avianca
Jan 16
SFO1:20 pmSan Francisco
16h 55m
2 stops
GYE9:15 amGuayaquil Jose Joaquin de Olmedo
Jan 29
GYE10:25 amGuayaquil Jose Joaquin de Olmedo
15h 55m
2 stops
SFO11:20 pmSan Francisco
$367
Find similar
Avianca
Apr 11
SFO2:20 pmSan Francisco
16h 25m
2 stops
GYE8:45 amGuayaquil Jose Joaquin de Olmedo
Apr 18
GYE9:45 amGuayaquil Jose Joaquin de Olmedo
16h 10m
2 stops
SFO11:55 pmSan Francisco
$387
Find similar
Avianca
Jan 19
SFO1:20 pmSan Francisco
16h 55m
2 stops
GYE9:15 amGuayaquil Jose Joaquin de Olmedo
Feb 2
GYE6:55 pmGuayaquil Jose Joaquin de Olmedo
20h 05m
2 stops
SFO12:00 pmSan Francisco
$395
Find similar

JetBlue flights from San Francisco to Guayaquil

Our best JetBlue deals on San Francisco to Guayaquil flight tickets
JetBlue
Jan 16
SFO11:59 pmSan Francisco
12h 36m
1 stop
GYE3:35 pmGuayaquil Jose Joaquin de Olmedo
Jan 29
GYE7:45 amGuayaquil Jose Joaquin de Olmedo
19h 37m
1 stop
SFO12:22 amSan Francisco
$521
Find similar
JetBlue
Jan 16
SFO12:40 pmSan Francisco
13h 36m
1 stop
GYE5:16 amGuayaquil Jose Joaquin de Olmedo
Jan 29
GYE7:45 amGuayaquil Jose Joaquin de Olmedo
18h 04m
1 stop
SFO10:49 pmSan Francisco
$532
Find similar
JetBlue
May 5
SFO9:00 pmSan Francisco
15h 55m
1 stop
GYE2:55 pmGuayaquil Jose Joaquin de Olmedo
May 7
GYE6:59 amGuayaquil Jose Joaquin de Olmedo
16h 14m
1 stop
SFO9:13 pmSan Francisco
$617
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 17, 2025.
Use the filters below to find and compare flights from San Francisco to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Fri 1/16

1:20 pm-9:15 am

2 stops16h 55m

Guayaquil Jose Joaquin de Olmedo

Thu 1/29

10:25 am-11:20 pm

2 stops15h 55m

$367

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Sun 1/18

12:42 am-11:42 pm

1 stop20h 00m

Guayaquil Jose Joaquin de Olmedo

Mon 2/2

8:34 am-11:20 pm

1 stop17h 46m

$386

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Sat 4/11

2:20 pm-8:45 am

2 stops16h 25m

Guayaquil Jose Joaquin de Olmedo

Sat 4/18

9:45 am-11:55 pm

2 stops16h 10m

$387

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 1/19

1:20 pm-9:15 am

2 stops16h 55m

Guayaquil Jose Joaquin de Olmedo

Mon 2/2

6:55 pm-12:00 pm

2 stops20h 05m

$395

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Thu 1/29

12:42 am-11:18 am

1 stop31h 36m

Guayaquil Jose Joaquin de Olmedo

Fri 2/6

6:33 pm-11:20 pm

1 stop31h 47m

$432

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Fri 1/16

11:20 pm-12:21 am

2 stops22h 01m

Guayaquil Jose Joaquin de Olmedo

Thu 1/29

2:35 pm-11:20 pm

1 stop11h 45m

$443

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Fri 1/30

11:10 pm-5:45 pm

2 stops15h 35m

Guayaquil Jose Joaquin de Olmedo

Fri 2/6

4:45 pm-10:31 am

1 stop20h 46m

$445

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Fri 1/16

1:20 pm-9:15 am

2 stops16h 55m

Guayaquil Jose Joaquin de Olmedo

Thu 1/29

6:55 pm-12:00 pm

2 stops20h 05m

$485

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 1/19

10:59 pm-11:22 pm

1 stop21h 23m

Guayaquil Jose Joaquin de Olmedo

Mon 2/2

7:15 am-11:12 pm

2 stops18h 57m

$498

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Fri 1/16

11:59 pm-3:35 pm

1 stop12h 36m

Guayaquil Jose Joaquin de Olmedo

Thu 1/29

7:45 am-12:22 am

1 stop19h 37m

$521

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from San Francisco to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Guayaquil?

The month of September is another great option to travel to Guayaquil, with average flight prices from San Francisco averaging around $492.

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from San Francisco to Guayaquil is on a Sunday. Travelers who choose to depart for Guayaquil on a Sunday will often find tickets for as low as $600. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Friday is $698.

What is the cheapest time of day to depart on your flight to Guayaquil?

The cheapest time of day to fly to Guayaquil is in the afternoon when flights can be purchased for as low as $578. Flights to Guayaquil are more costly in the evening, with an average ticket price of $676. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Guayaquil?

You are more likely to see cheaper flights to Guayaquil from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Guayaquil for around $641 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Guayaquil from San Francisco for as low as $444 on momondo.

How have San Francisco to Guayaquil flight prices changed over time?

As of December 2025, prices for San Francisco to Guayaquil flights are approximately 18% cheaper when compared to flights at the same time last year.

When to book flights from San Francisco to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Guayaquil (SFO to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Guayaquil

Fastest flight time

13h 22m

Direct flights

None
The fastest flight from San Francisco to Guayaquil takes 13h 22m
There are no direct flights from San Francisco to Guayaquil. There are no popular flight routes from San Francisco to Guayaquil.
Search flight deals

  • How far is San Francisco to Guayaquil Jose Joaquin de Olmedo by plane?

    The straight-line distance from San Francisco to Guayaquil Jose Joaquin de Olmedo is 3869.7 mi. By plane, this route typically takes 13h 22m.

  • When did momondo last update prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Guayaquil?

Best airlines flying from San Francisco to Guayaquil

Compare and see reviews for airlines that fly from San Francisco to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $203Free CancellationRating
7.2
2,895 reviews
Search JetBlue flights
AviancaPriceFrom $432Free CancellationRating
6.6
2,487 reviews
Search Avianca flights
Copa AirlinesPriceFrom $440Free CancellationRating
7.6
1,556 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $486Free CancellationRating
7.4
9,092 reviews
Search United Airlines flights
American AirlinesPriceFrom $570Free CancellationRating
7.2
11,049 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Guayaquil for you.

Can I find flights from San Francisco to Guayaquil with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guayaquil from San Francisco with this policy.

How can momondo help me find flights from San Francisco to Guayaquil?

Once you have performed a search for San Francisco to Guayaquil flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Guayaquil right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guayaquil from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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