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Cheap flights from San Francisco to Guayaquil from $281

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
11:10 pm - 3:22 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
14h 12m1 stop Fort Lauderdale
JetBlue Logo
1:30 pm - 12:07 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
12h 37m1 stop Fort Lauderdale
$498JetBlue
Fri, Oct 9 - Mon, Oct 12
Copa Airlines Logo
8:21 pm - 12:01 amSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
25h 40m1 stop Panama City Tocumen Intl
Copa Airlines Logo
8:23 am - 11:40 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
17h 17m1 stop Panama City Tocumen Intl
$572Copa Airlines
Thu, Oct 15 - Sun, Oct 25
Copa Airlines Logo
8:21 pm - 11:37 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
25h 16m1 stop Panama City Tocumen Intl
Copa Airlines Logo
2:45 pm - 11:40 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
10h 55m1 stop Panama City Tocumen Intl
$572Copa Airlines
Thu, Oct 15 - Sun, Oct 25
American Airlines Logo
11:44 pm - 11:16 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
20h 32m1 stop Miami
American Airlines Logo
6:00 am - 1:06 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
22h 06m1 stop Miami
$584American Airlines
Mon, Nov 9 - Mon, Nov 23
American Airlines Logo
11:23 pm - 11:16 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
20h 53m2 stops Dallas/Fort Worth Miami
American Airlines Logo
6:00 am - 10:53 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
19h 53m1 stop Miami
$589American Airlines
Mon, Nov 9 - Mon, Nov 23
JetBlue Logo
11:10 pm - 3:22 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
14h 12m1 stop Fort Lauderdale
JetBlue Logo
1:30 pm - 12:07 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
12h 37m1 stop Fort Lauderdale
$589JetBlue
Mon, Oct 19 - Thu, Oct 22
Avianca Logo
2:15 pm - 8:55 amSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
16h 40m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
10:05 am - 10:35 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
14h 30m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$639Avianca
Sat, Sep 19 - Thu, Sep 24
Avianca Logo
11:55 pm - 5:35 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
15h 40m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
9:15 pm - 12:55 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
17h 40m2 stops Quito Mariscal Sucr San Salvador El Salvador Intl
$639Avianca
Thu, Oct 15 - Sun, Oct 25
GOL Logo
5:00 pm - 10:10 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
27h 10m2 stops Dallas/Fort Worth Miami
GOL Logo
6:00 am - 11:59 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
19h 59m1 stop Miami
$653GOL
Sat, Sep 19 - Thu, Sep 24
Multiple Airlines Logo
11:55 pm - 12:22 amSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
22h 27m3 stops San Salvador El Salvador Intl Bogotá El Dorado Quito Mariscal Sucr
Multiple Airlines Logo
10:05 am - 10:35 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
14h 30m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$824Multiple Airlines
Thu, Oct 15 - Tue, Oct 20

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JetBlue flights from San Francisco to Guayaquil

Our best JetBlue deals on San Francisco to Guayaquil flight tickets
JetBlue
Oct 9
SFO11:10 pmSan Francisco
14h 12m
1 stop
GYE3:22 pmGuayaquil Jose Joaquin de Olmedo
Oct 12
GYE1:30 pmGuayaquil Jose Joaquin de Olmedo
12h 37m
1 stop
SFO12:07 amSan Francisco
$498
JetBlue
Nov 17
SFO2:35 pmSan Francisco
18h 30m
1 stop
GYE12:05 pmGuayaquil Jose Joaquin de Olmedo
Dec 1
GYE6:00 pmGuayaquil Jose Joaquin de Olmedo
19h 04m
1 stop
SFO10:04 amSan Francisco
$631
JetBlue
Oct 1
SFO11:10 pmSan Francisco
14h 04m
1 stop
GYE3:14 pmGuayaquil Jose Joaquin de Olmedo
Oct 8
GYE1:30 pmGuayaquil Jose Joaquin de Olmedo
12h 37m
1 stop
SFO12:07 amSan Francisco
$674

Copa Airlines flights from San Francisco to Guayaquil

Our best Copa Airlines deals on San Francisco to Guayaquil flight tickets
Copa Airlines
Oct 15
SFO8:21 pmSan Francisco
13h 00m
1 stop
GYE11:21 amGuayaquil Jose Joaquin de Olmedo
Oct 20
GYE2:33 pmGuayaquil Jose Joaquin de Olmedo
29h 37m
1 stop
SFO6:10 pmSan Francisco
$572
Copa Airlines
Oct 7
SFO8:21 pmSan Francisco
13h 00m
1 stop
GYE11:21 amGuayaquil Jose Joaquin de Olmedo
Oct 18
GYE4:14 amGuayaquil Jose Joaquin de Olmedo
21h 26m
1 stop
SFO11:40 pmSan Francisco
$608
Copa Airlines
Aug 31
SFO1:12 amSan Francisco
20h 25m
1 stop
GYE11:37 pmGuayaquil Jose Joaquin de Olmedo
Sep 15
GYE6:28 pmGuayaquil Jose Joaquin de Olmedo
25h 42m
1 stop
SFO6:10 pmSan Francisco
$632

momondo Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Fri 10/9

11:10 pm-3:22 pm

1 stop14h 12m

Guayaquil Jose Joaquin de Olmedo

Mon 10/12

1:30 pm-12:07 am

1 stop12h 37m

$498

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Thu 10/15

8:21 pm-12:01 am

1 stop25h 40m

Guayaquil Jose Joaquin de Olmedo

Sun 10/25

8:23 am-11:40 pm

1 stop17h 17m

$572

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Thu 10/15

8:21 pm-11:37 pm

1 stop25h 16m

Guayaquil Jose Joaquin de Olmedo

Sun 10/25

2:45 pm-11:40 pm

1 stop10h 55m

$572

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Mon 11/9

11:44 pm-11:16 pm

1 stop20h 32m

Guayaquil Jose Joaquin de Olmedo

Mon 11/23

6:00 am-1:06 am

1 stop22h 06m

$584

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Mon 11/9

11:23 pm-11:16 pm

2 stops20h 53m

Guayaquil Jose Joaquin de Olmedo

Mon 11/23

6:00 am-10:53 pm

1 stop19h 53m

$589

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Mon 10/19

11:10 pm-3:22 pm

1 stop14h 12m

Guayaquil Jose Joaquin de Olmedo

Thu 10/22

1:30 pm-12:07 am

1 stop12h 37m

$589

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sat 9/19

2:15 pm-8:55 am

2 stops16h 40m

Guayaquil Jose Joaquin de Olmedo

Thu 9/24

10:05 am-10:35 pm

2 stops14h 30m

$639

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Thu 10/15

11:55 pm-5:35 pm

2 stops15h 40m

Guayaquil Jose Joaquin de Olmedo

Sun 10/25

9:15 pm-12:55 pm

2 stops17h 40m

$639

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sat 9/19

5:00 pm-10:10 pm

2 stops27h 10m

Guayaquil Jose Joaquin de Olmedo

Thu 9/24

6:00 am-11:59 pm

1 stop19h 59m

$653

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Thu 10/15

11:55 pm-12:22 am

3 stops22h 27m

Guayaquil Jose Joaquin de Olmedo

Tue 10/20

10:05 am-10:35 pm

2 stops14h 30m

$824

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from San Francisco to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Guayaquil?

Prices are currently low for flights on this route.

Typical prices usually range from $524 to $612.
The lowest price recently found on this route was $498.

What is the cheapest month to fly to Guayaquil?

The month of September is another great option to travel to Guayaquil, with average flight prices from San Francisco averaging around $498.

How far in advance should I book a flight from San Francisco to Guayaquil?

You are more likely to see cheaper flights to Guayaquil from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Guayaquil for around $635 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Guayaquil from San Francisco for as low as $545 on momondo.

Can stopping save me money on San Francisco to Guayaquil flights?

You could potentially save up to 66% on your flight if you consider stops on a San Francisco to Guayaquil flight.

How have San Francisco to Guayaquil flight prices changed over time?

As of August 2026, prices for San Francisco to Guayaquil flights are approximately 7% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Guayaquil (SFO to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Guayaquil

Best Price Found

$281

Fastest flight time

13h 00m

Direct flights

None
The best one-way flight to Guayaquil from San Francisco in the past 72 hours is $281. The best round-trip flight deal from San Francisco to Guayaquil found on momondo in the last 72 hours is $498.
The fastest flight from San Francisco to Guayaquil takes 13h 00m
There are no direct flights from San Francisco to Guayaquil. There are no popular flight routes from San Francisco to Guayaquil.
Search flight deals

Frequently asked questions about flying from San Francisco to Guayaquil

  • How far is San Francisco to Guayaquil Jose Joaquin de Olmedo by plane?

    The straight-line distance from San Francisco to Guayaquil Jose Joaquin de Olmedo is 3868.8 mi. By plane, this route typically takes 13h 00m.

  • When did momondo last update prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Guayaquil?

Best airlines flying from San Francisco to Guayaquil

Compare and see reviews for airlines that fly from San Francisco to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $203Free CancellationRating
7.1
3,039 reviews
Search JetBlue flights
Copa AirlinesPriceFrom $289Free CancellationRating
7.6
1,553 reviews
Search Copa Airlines flights
AviancaPriceFrom $472Free CancellationRating
6.5
2,546 reviews
Search Avianca flights
United AirlinesPriceFrom $486Free CancellationRating
7.4
10,112 reviews
Search United Airlines flights
American AirlinesPriceFrom $570Free CancellationRating
7.1
11,990 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Guayaquil for you.

Can I find flights from San Francisco to Guayaquil with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guayaquil from San Francisco with this policy.

How can momondo help me find flights from San Francisco to Guayaquil?

Once you have performed a search for San Francisco to Guayaquil flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Guayaquil right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guayaquil from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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