Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from San Francisco to Guayaquil from $348

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Guayaquil departing on 1/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from San Francisco to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
1:20 pm - 9:15 am
SFO
-
GYE
16h 55m2 stops
Avianca Logo
6:55 pm - 12:00 pm
GYE
-
SFO
20h 05m2 stops
$348Avianca
Mon, Jan 19 - Mon, Feb 2
Avianca Logo
11:10 pm - 11:35 pm
SFO
-
GYE
21h 25m2 stops
Avianca Logo
6:55 pm - 12:00 pm
GYE
-
SFO
20h 05m2 stops
$367Avianca
Mon, Feb 2 - Mon, Feb 9
Copa Airlines Logo
12:42 am - 5:35 pm
SFO
-
GYE
13h 53m1 stop
Copa Airlines Logo
2:35 pm - 11:20 pm
GYE
-
SFO
11h 45m1 stop
$386Copa Airlines
Sun, Jan 18 - Mon, Feb 2
Multiple Airlines Logo
11:10 pm - 5:45 pm
SFO
-
GYE
15h 35m2 stops
Multiple Airlines Logo
7:45 am - 10:49 pm
GYE
-
SFO
18h 04m1 stop
$399Multiple Airlines
Mon, Jan 19 - Mon, Feb 2
Avianca Logo
2:20 pm - 8:35 am
SFO
-
GYE
16h 15m2 stops
Avianca Logo
3:35 am - 10:45 pm
GYE
-
SFO
21h 10m2 stops
$408Avianca
Fri, Apr 10 - Thu, Apr 16
Copa Airlines Logo
12:42 am - 11:18 am
SFO
-
GYE
31h 36m1 stop
Copa Airlines Logo
8:34 am - 11:20 pm
GYE
-
SFO
17h 46m1 stop
$412Copa Airlines
Sat, Jan 17 - Thu, Jan 22
JetBlue Logo
12:40 pm - 5:16 am
SFO
-
GYE
13h 36m1 stop
JetBlue Logo
7:45 am - 10:49 pm
GYE
-
SFO
18h 04m1 stop
$416JetBlue
Mon, Jan 19 - Mon, Feb 2
JetBlue Logo
12:40 pm - 5:16 am
SFO
-
GYE
13h 36m1 stop
JetBlue Logo
7:45 am - 10:49 pm
GYE
-
SFO
18h 04m1 stop
$418JetBlue
Mon, Jan 26 - Mon, Feb 2
Avianca Logo
2:20 pm - 9:00 am
SFO
-
GYE
16h 40m2 stops
Avianca Logo
8:50 am - 10:45 pm
GYE
-
SFO
15h 55m2 stops
$438Avianca
Sat, Apr 11 - Sat, Apr 18
Avianca Logo
11:10 pm - 11:35 pm
SFO
-
GYE
21h 25m2 stops
Avianca Logo
6:55 pm - 12:00 pm
GYE
-
SFO
20h 05m2 stops
$442Avianca
Mon, Jan 19 - Mon, Feb 2

Avianca flights from San Francisco to Guayaquil

Our best Avianca deals on San Francisco to Guayaquil flight tickets
Avianca
Jan 19
SFO1:20 pmSan Francisco
16h 55m
2 stops
GYE9:15 amGuayaquil Jose Joaquin de Olmedo
Feb 2
GYE6:55 pmGuayaquil Jose Joaquin de Olmedo
20h 05m
2 stops
SFO12:00 pmSan Francisco
$348
Find similar
Avianca
Feb 2
SFO11:10 pmSan Francisco
21h 25m
2 stops
GYE11:35 pmGuayaquil Jose Joaquin de Olmedo
Feb 9
GYE6:55 pmGuayaquil Jose Joaquin de Olmedo
20h 05m
2 stops
SFO12:00 pmSan Francisco
$367
Find similar
Avianca
Apr 10
SFO2:20 pmSan Francisco
16h 15m
2 stops
GYE8:35 amGuayaquil Jose Joaquin de Olmedo
Apr 16
GYE3:35 amGuayaquil Jose Joaquin de Olmedo
21h 10m
2 stops
SFO10:45 pmSan Francisco
$408
Find similar

Copa Airlines flights from San Francisco to Guayaquil

Our best Copa Airlines deals on San Francisco to Guayaquil flight tickets
Copa Airlines
Jan 18
SFO12:42 amSan Francisco
13h 53m
1 stop
GYE5:35 pmGuayaquil Jose Joaquin de Olmedo
Feb 2
GYE2:35 pmGuayaquil Jose Joaquin de Olmedo
11h 45m
1 stop
SFO11:20 pmSan Francisco
$386
Find similar
Copa Airlines
Jan 17
SFO12:42 amSan Francisco
31h 36m
1 stop
GYE11:18 amGuayaquil Jose Joaquin de Olmedo
Jan 22
GYE8:34 amGuayaquil Jose Joaquin de Olmedo
17h 46m
1 stop
SFO11:20 pmSan Francisco
$412
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 21, 2025.
Use the filters below to find and compare flights from San Francisco to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 1/19

1:20 pm-9:15 am

2 stops16h 55m

Guayaquil Jose Joaquin de Olmedo

Mon 2/2

6:55 pm-12:00 pm

2 stops20h 05m

$348

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 2/2

11:10 pm-11:35 pm

2 stops21h 25m

Guayaquil Jose Joaquin de Olmedo

Mon 2/9

6:55 pm-12:00 pm

2 stops20h 05m

$367

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Sun 1/18

12:42 am-5:35 pm

1 stop13h 53m

Guayaquil Jose Joaquin de Olmedo

Mon 2/2

2:35 pm-11:20 pm

1 stop11h 45m

$386

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 1/19

11:10 pm-5:45 pm

2 stops15h 35m

Guayaquil Jose Joaquin de Olmedo

Mon 2/2

7:45 am-10:49 pm

1 stop18h 04m

$399

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Fri 4/10

2:20 pm-8:35 am

2 stops16h 15m

Guayaquil Jose Joaquin de Olmedo

Thu 4/16

3:35 am-10:45 pm

2 stops21h 10m

$408

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Sat 1/17

12:42 am-11:18 am

1 stop31h 36m

Guayaquil Jose Joaquin de Olmedo

Thu 1/22

8:34 am-11:20 pm

1 stop17h 46m

$412

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 1/19

12:40 pm-5:16 am

1 stop13h 36m

Guayaquil Jose Joaquin de Olmedo

Mon 2/2

7:45 am-10:49 pm

1 stop18h 04m

$416

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 1/26

12:40 pm-5:16 am

1 stop13h 36m

Guayaquil Jose Joaquin de Olmedo

Mon 2/2

7:45 am-10:49 pm

1 stop18h 04m

$418

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Sat 4/11

2:20 pm-9:00 am

2 stops16h 40m

Guayaquil Jose Joaquin de Olmedo

Sat 4/18

8:50 am-10:45 pm

2 stops15h 55m

$438

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 1/19

11:10 pm-11:35 pm

2 stops21h 25m

Guayaquil Jose Joaquin de Olmedo

Mon 2/2

6:55 pm-12:00 pm

2 stops20h 05m

$442

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Guayaquil from

How to get the cheapest flight ticket from San Francisco to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Guayaquil?

The month of September is another great option to travel to Guayaquil, with average flight prices from San Francisco averaging around $492.

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from San Francisco to Guayaquil is on a Sunday. Travelers who choose to depart for Guayaquil on a Sunday will often find tickets for as low as $600. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Friday is $698.

What is the cheapest time of day to depart on your flight to Guayaquil?

The cheapest time of day to fly to Guayaquil is in the afternoon when flights can be purchased for as low as $578. Flights to Guayaquil are more costly in the evening, with an average ticket price of $676. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

How far in advance should I book a flight to Guayaquil?

You are more likely to see cheaper flights to Guayaquil from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Guayaquil for around $641 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Guayaquil from San Francisco for as low as $444 on momondo.

How have San Francisco to Guayaquil flight prices changed over time?

As of December 2025, prices for San Francisco to Guayaquil flights are approximately 18% cheaper when compared to flights at the same time last year.

When to book flights from San Francisco to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Guayaquil (SFO to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Guayaquil

Fastest flight time

13h 51m

Direct flights

None
The fastest flight from San Francisco to Guayaquil takes 13h 51m
There are no direct flights from San Francisco to Guayaquil. There are no popular flight routes from San Francisco to Guayaquil.
Search flight deals

  • How far is San Francisco to Guayaquil Jose Joaquin de Olmedo by plane?

    The straight-line distance from San Francisco to Guayaquil Jose Joaquin de Olmedo is 3869.7 mi. By plane, this route typically takes 13h 51m.

  • When did momondo last update prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Guayaquil?

Best airlines flying from San Francisco to Guayaquil

Compare and see reviews for airlines that fly from San Francisco to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $203Free CancellationRating
7.2
2,895 reviews
Search JetBlue flights
AviancaPriceFrom $432Free CancellationRating
6.6
2,488 reviews
Search Avianca flights
Copa AirlinesPriceFrom $440Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $486Free CancellationRating
7.4
9,100 reviews
Search United Airlines flights
American AirlinesPriceFrom $570Free CancellationRating
7.2
11,051 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Guayaquil for you.

Can I find flights from San Francisco to Guayaquil with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guayaquil from San Francisco with this policy.

How can momondo help me find flights from San Francisco to Guayaquil?

Once you have performed a search for San Francisco to Guayaquil flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Guayaquil right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guayaquil from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Guayaquil trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 1/20
Tue 1/27
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Ecuador