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Cheap flights from San Francisco to Guayaquil from $312

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
11:10 pm - 3:24 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
14h 14m1 stop Fort Lauderdale
JetBlue Logo
1:30 pm - 12:07 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
12h 37m1 stop Fort Lauderdale
$503JetBlue
Mon, Oct 19 - Thu, Oct 22
JetBlue Logo
11:10 pm - 3:24 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
14h 14m1 stop Fort Lauderdale
JetBlue Logo
5:54 pm - 9:34 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
18h 40m1 stop New York John F Kennedy Intl
$523JetBlue
Mon, Oct 19 - Mon, Nov 2
Copa Airlines Logo
8:21 pm - 11:21 amSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
13h 00m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:01 am - 11:40 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
19h 39m1 stop Panama City Tocumen Intl
$572Copa Airlines
Thu, Oct 15 - Sun, Oct 25
Copa Airlines Logo
8:21 pm - 12:01 amSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
25h 40m1 stop Panama City Tocumen Intl
Copa Airlines Logo
8:23 am - 11:40 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
17h 17m1 stop Panama City Tocumen Intl
$572Copa Airlines
Thu, Oct 15 - Sun, Oct 25
American Airlines Logo
5:22 pm - 2:34 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
18h 12m2 stops Chicago O'Hare Intl Miami
American Airlines Logo
6:00 am - 7:28 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
16h 28m2 stops Miami Dallas/Fort Worth
$589American Airlines
Sat, Nov 14 - Tue, Nov 24
American Airlines Logo
5:22 pm - 2:34 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
18h 12m2 stops Chicago O'Hare Intl Miami
American Airlines Logo
6:00 am - 12:58 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
21h 58m1 stop Miami
$589American Airlines
Sat, Nov 14 - Tue, Nov 24
GOL Logo
1:57 pm - 2:34 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
21h 37m2 stops Dallas/Fort Worth Miami
GOL Logo
6:00 am - 10:47 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
19h 47m1 stop Miami
$634GOL
Fri, Nov 6 - Wed, Nov 11
GOL Logo
11:43 pm - 10:42 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
19h 59m2 stops Philadelphia Miami
GOL Logo
3:31 pm - 12:36 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
24h 05m2 stops Miami Charlotte Douglas
$634GOL
Sat, Feb 13 - Sun, Feb 21
Avianca Logo
1:15 pm - 9:00 amSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
16h 45m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
7:35 pm - 11:55 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
19h 20m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$639Avianca
Fri, Nov 13 - Mon, Nov 23
Avianca Logo
11:55 pm - 5:35 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
15h 40m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
9:15 pm - 12:55 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
17h 40m2 stops Quito Mariscal Sucr San Salvador El Salvador Intl
$639Avianca
Thu, Oct 15 - Sun, Oct 25

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American Airlines flights from San Francisco to Guayaquil

Our best American Airlines deals on San Francisco to Guayaquil flight tickets
American Airlines
Nov 13
SFO9:35 pmSan Francisco
13h 59m
1 stop
GYE2:34 pmGuayaquil Jose Joaquin de Olmedo
Nov 23
GYE3:35 pmGuayaquil Jose Joaquin de Olmedo
22h 17m
1 stop
SFO10:52 amSan Francisco
$607
American Airlines
Nov 13
SFO9:35 pmSan Francisco
13h 59m
1 stop
GYE2:34 pmGuayaquil Jose Joaquin de Olmedo
Nov 23
GYE3:35 pmGuayaquil Jose Joaquin de Olmedo
20h 25m
2 stops
SFO9:00 amSan Francisco
$612
American Airlines
Nov 14
SFO9:35 pmSan Francisco
22h 41m
1 stop
GYE11:16 pmGuayaquil Jose Joaquin de Olmedo
Nov 24
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
16h 23m
1 stop
SFO7:23 pmSan Francisco
$623

GOL flights from San Francisco to Guayaquil

Our best GOL deals on San Francisco to Guayaquil flight tickets
GOL
Nov 6
SFO1:57 pmSan Francisco
21h 37m
2 stops
GYE2:34 pmGuayaquil Jose Joaquin de Olmedo
Nov 11
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
19h 47m
1 stop
SFO10:47 pmSan Francisco
$634
GOL
Sep 19
SFO2:00 pmSan Francisco
30h 10m
2 stops
GYE10:10 pmGuayaquil Jose Joaquin de Olmedo
Sep 26
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
19h 59m
1 stop
SFO11:59 pmSan Francisco
$665
GOL
Dec 2
SFO9:35 pmSan Francisco
13h 56m
1 stop
GYE2:31 pmGuayaquil Jose Joaquin de Olmedo
Jan 5
GYE3:30 pmGuayaquil Jose Joaquin de Olmedo
21h 52m
2 stops
SFO10:22 amSan Francisco
$848

momondo Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Mon 10/19

11:10 pm-3:24 pm

1 stop14h 14m

Guayaquil Jose Joaquin de Olmedo

Thu 10/22

1:30 pm-12:07 am

1 stop12h 37m

$503

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Mon 10/19

11:10 pm-3:24 pm

1 stop14h 14m

Guayaquil Jose Joaquin de Olmedo

Mon 11/2

5:54 pm-9:34 am

1 stop18h 40m

$523

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Thu 10/15

8:21 pm-11:21 am

1 stop13h 00m

Guayaquil Jose Joaquin de Olmedo

Sun 10/25

6:01 am-11:40 pm

1 stop19h 39m

$572

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Thu 10/15

8:21 pm-12:01 am

1 stop25h 40m

Guayaquil Jose Joaquin de Olmedo

Sun 10/25

8:23 am-11:40 pm

1 stop17h 17m

$572

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sat 11/14

5:22 pm-2:34 pm

2 stops18h 12m

Guayaquil Jose Joaquin de Olmedo

Tue 11/24

6:00 am-7:28 pm

2 stops16h 28m

$589

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sat 11/14

5:22 pm-2:34 pm

2 stops18h 12m

Guayaquil Jose Joaquin de Olmedo

Tue 11/24

6:00 am-12:58 am

1 stop21h 58m

$589

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Fri 11/6

1:57 pm-2:34 pm

2 stops21h 37m

Guayaquil Jose Joaquin de Olmedo

Wed 11/11

6:00 am-10:47 pm

1 stop19h 47m

$634

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sat 2/13

11:43 pm-10:42 pm

2 stops19h 59m

Guayaquil Jose Joaquin de Olmedo

Sun 2/21

3:31 pm-12:36 pm

2 stops24h 05m

$634

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Fri 11/13

1:15 pm-9:00 am

2 stops16h 45m

Guayaquil Jose Joaquin de Olmedo

Mon 11/23

7:35 pm-11:55 am

2 stops19h 20m

$639

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Thu 10/15

11:55 pm-5:35 pm

2 stops15h 40m

Guayaquil Jose Joaquin de Olmedo

Sun 10/25

9:15 pm-12:55 pm

2 stops17h 40m

$639

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from San Francisco to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Guayaquil?

Prices are currently typical for flights on this route.

Typical prices usually range from $486 to $550.
The lowest price recently found on this route was $503.

What is the cheapest month to fly to Guayaquil?

The month of September is another great option to travel to Guayaquil, with average flight prices from San Francisco averaging around $498.

How far in advance should I book a flight from San Francisco to Guayaquil?

You are more likely to see cheaper flights to Guayaquil from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Guayaquil for around $639 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Guayaquil from San Francisco for as low as $545 on momondo.

Can stopping save me money on San Francisco to Guayaquil flights?

You could potentially save up to 57% on your flight if you consider stops on a San Francisco to Guayaquil flight.

How have San Francisco to Guayaquil flight prices changed over time?

As of August 2026, prices for San Francisco to Guayaquil flights are approximately 24% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Guayaquil (SFO to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Guayaquil

Best Price Found

$312

Fastest flight time

11h 44m

Direct flights

None
The best one-way flight to Guayaquil from San Francisco in the past 72 hours is $312. The best round-trip flight deal from San Francisco to Guayaquil found on momondo in the last 72 hours is $503.
The fastest flight from San Francisco to Guayaquil takes 11h 44m
There are no direct flights from San Francisco to Guayaquil. There are no popular flight routes from San Francisco to Guayaquil.
Search flight deals

Frequently asked questions about flying from San Francisco to Guayaquil

  • How far is San Francisco to Guayaquil Jose Joaquin de Olmedo by plane?

    The straight-line distance from San Francisco to Guayaquil Jose Joaquin de Olmedo is 3868.8 mi. By plane, this route typically takes 11h 44m.

  • When did momondo last update prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Guayaquil?

Best airlines flying from San Francisco to Guayaquil

Compare and see reviews for airlines that fly from San Francisco to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $203Free CancellationRating
7.1
3,033 reviews
Search JetBlue flights
Copa AirlinesPriceFrom $289Free CancellationRating
7.6
1,550 reviews
Search Copa Airlines flights
AviancaPriceFrom $472Free CancellationRating
6.5
2,551 reviews
Search Avianca flights
United AirlinesPriceFrom $486Free CancellationRating
7.4
10,138 reviews
Search United Airlines flights
American AirlinesPriceFrom $570Free CancellationRating
7.1
12,017 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Guayaquil for you.

Can I find flights from San Francisco to Guayaquil with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guayaquil from San Francisco with this policy.

How can momondo help me find flights from San Francisco to Guayaquil?

Once you have performed a search for San Francisco to Guayaquil flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Guayaquil right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guayaquil from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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