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Cheap flights from San Francisco to Guayaquil from $176

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Guayaquil departing on 5/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from San Francisco to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
11:55 pm - 5:35 pm
SFO
-
GYE
15h 40m
2 stops
Avianca Logo
9:10 am - 11:55 pm
GYE
-
SFO
16h 45m
2 stops
$399Avianca
Mon, May 4 - Tue, May 12
JetBlue Logo
8:35 pm - 2:25 pm
SFO
-
GYE
15h 50m
1 stop
JetBlue Logo
12:25 pm - 11:54 pm
GYE
-
SFO
13h 29m
1 stop
$409JetBlue
Tue, Sep 1 - Fri, Sep 4
JetBlue Logo
2:45 pm - 10:58 am
SFO
-
GYE
18h 13m
1 stop
JetBlue Logo
12:25 pm - 11:56 pm
GYE
-
SFO
13h 31m
1 stop
$432JetBlue
Fri, May 1 - Tue, May 12
Avianca Logo
11:55 pm - 5:35 pm
SFO
-
GYE
15h 40m
2 stops
Avianca Logo
6:50 pm - 11:55 pm
GYE
-
SFO
31h 05m
2 stops
$444Avianca
Wed, Apr 22 - Mon, Apr 27
JetBlue Logo
2:45 pm - 10:58 am
SFO
-
GYE
18h 13m
1 stop
JetBlue Logo
12:25 pm - 11:56 pm
GYE
-
SFO
13h 31m
1 stop
$456JetBlue
Mon, May 4 - Tue, May 12
Avianca Logo
2:15 pm - 2:35 pm
SFO
-
GYE
22h 20m
2 stops
Avianca Logo
6:50 pm - 11:55 pm
GYE
-
SFO
31h 05m
2 stops
$464Avianca
Wed, Apr 22 - Mon, Apr 27
Multiple Airlines Logo
2:15 pm - 2:35 pm
SFO
-
GYE
22h 20m
2 stops
Multiple Airlines Logo
4:00 pm - 9:23 am
GYE
-
SFO
19h 23m
1 stop
$468Multiple Airlines
Mon, May 4 - Tue, May 12
Copa Airlines Logo
1:23 am - 1:35 pm
SFO
-
GYE
10h 12m
1 stop
Copa Airlines Logo
2:43 pm - 11:40 pm
GYE
-
SFO
10h 57m
1 stop
$469Copa Airlines
Tue, Apr 21 - Mon, Apr 27
Avianca Logo
2:15 pm - 5:35 pm
SFO
-
GYE
25h 20m
2 stops
Avianca Logo
3:45 pm - 11:55 pm
GYE
-
SFO
34h 10m
2 stops
$471Avianca
Mon, Apr 13 - Mon, Apr 20
Avianca Logo
11:55 pm - 5:35 pm
SFO
-
GYE
15h 40m
2 stops
Avianca Logo
6:50 pm - 10:35 pm
GYE
-
SFO
29h 45m
2 stops
$472Avianca
Tue, Apr 21 - Tue, Apr 28

JetBlue flights from San Francisco to Guayaquil

Our best JetBlue deals on San Francisco to Guayaquil flight tickets
JetBlue
Sep 1
SFO8:35 pmSan Francisco
15h 50m
1 stop
GYE2:25 pmGuayaquil Jose Joaquin de Olmedo
Sep 4
GYE12:25 pmGuayaquil Jose Joaquin de Olmedo
13h 29m
1 stop
SFO11:54 pmSan Francisco
$409
JetBlue
May 1
SFO2:45 pmSan Francisco
18h 13m
1 stop
GYE10:58 amGuayaquil Jose Joaquin de Olmedo
May 12
GYE12:25 pmGuayaquil Jose Joaquin de Olmedo
13h 31m
1 stop
SFO11:56 pmSan Francisco
$432
JetBlue
May 4
SFO2:45 pmSan Francisco
18h 13m
1 stop
GYE10:58 amGuayaquil Jose Joaquin de Olmedo
May 12
GYE12:25 pmGuayaquil Jose Joaquin de Olmedo
13h 31m
1 stop
SFO11:56 pmSan Francisco
$456

Copa Airlines flights from San Francisco to Guayaquil

Our best Copa Airlines deals on San Francisco to Guayaquil flight tickets
Copa Airlines
Apr 21
SFO1:23 amSan Francisco
10h 12m
1 stop
GYE1:35 pmGuayaquil Jose Joaquin de Olmedo
Apr 27
GYE2:43 pmGuayaquil Jose Joaquin de Olmedo
10h 57m
1 stop
SFO11:40 pmSan Francisco
$469
Copa Airlines
May 7
SFO8:06 pmSan Francisco
15h 27m
1 stop
GYE1:33 pmGuayaquil Jose Joaquin de Olmedo
May 17
GYE12:22 pmGuayaquil Jose Joaquin de Olmedo
13h 18m
1 stop
SFO11:40 pmSan Francisco
$476
Copa Airlines
May 3
SFO8:06 pmSan Francisco
15h 27m
1 stop
GYE1:33 pmGuayaquil Jose Joaquin de Olmedo
May 12
GYE12:22 pmGuayaquil Jose Joaquin de Olmedo
13h 18m
1 stop
SFO11:40 pmSan Francisco
$558

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 7, 2026.
Use the filters below to find and compare flights from San Francisco to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 5/4

11:55 pm-5:35 pm

2 stops15h 40m

Guayaquil Jose Joaquin de Olmedo

Tue 5/12

9:10 am-11:55 pm

2 stops16h 45m

$399

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Tue 9/1

8:35 pm-2:25 pm

1 stop15h 50m

Guayaquil Jose Joaquin de Olmedo

Fri 9/4

12:25 pm-11:54 pm

1 stop13h 29m

$409

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Fri 5/1

2:45 pm-10:58 am

1 stop18h 13m

Guayaquil Jose Joaquin de Olmedo

Tue 5/12

12:25 pm-11:56 pm

1 stop13h 31m

$432

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Wed 4/22

11:55 pm-5:35 pm

2 stops15h 40m

Guayaquil Jose Joaquin de Olmedo

Mon 4/27

6:50 pm-11:55 pm

2 stops31h 05m

$444

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 5/4

2:45 pm-10:58 am

1 stop18h 13m

Guayaquil Jose Joaquin de Olmedo

Tue 5/12

12:25 pm-11:56 pm

1 stop13h 31m

$456

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Wed 4/22

2:15 pm-2:35 pm

2 stops22h 20m

Guayaquil Jose Joaquin de Olmedo

Mon 4/27

6:50 pm-11:55 pm

2 stops31h 05m

$464

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 5/4

2:15 pm-2:35 pm

2 stops22h 20m

Guayaquil Jose Joaquin de Olmedo

Tue 5/12

4:00 pm-9:23 am

1 stop19h 23m

$468
Quickest round-trip

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Tue 4/21

1:23 am-1:35 pm

1 stop10h 12m

Guayaquil Jose Joaquin de Olmedo

Mon 4/27

2:43 pm-11:40 pm

1 stop10h 57m

$469

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 4/13

2:15 pm-5:35 pm

2 stops25h 20m

Guayaquil Jose Joaquin de Olmedo

Mon 4/20

3:45 pm-11:55 pm

2 stops34h 10m

$471

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Tue 4/21

11:55 pm-5:35 pm

2 stops15h 40m

Guayaquil Jose Joaquin de Olmedo

Tue 4/28

6:50 pm-10:35 pm

2 stops29h 45m

$472

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from San Francisco to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Guayaquil?

What is the cheapest month to fly to Guayaquil?

The month of September is another great option to travel to Guayaquil, with average flight prices from San Francisco averaging around $492.

How far in advance should I book a flight to Guayaquil?

You are more likely to see cheaper flights to Guayaquil from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Guayaquil for around $622 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Guayaquil from San Francisco for as low as $459 on momondo.

Can stopping save me money on San Francisco to Guayaquil flights?

You could potentially save up to 6% on your flight if you consider stops on a San Francisco to Guayaquil flight.

How have San Francisco to Guayaquil flight prices changed over time?

As of March 2026, prices for San Francisco to Guayaquil flights are approximately 16% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Guayaquil (SFO to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Guayaquil

Fastest flight time

13h 15m

Direct flights

None
The fastest flight from San Francisco to Guayaquil takes 13h 15m
There are no direct flights from San Francisco to Guayaquil. There are no popular flight routes from San Francisco to Guayaquil.
Search flight deals

  • How far is San Francisco to Guayaquil Jose Joaquin de Olmedo by plane?

    The straight-line distance from San Francisco to Guayaquil Jose Joaquin de Olmedo is 3869.7 mi. By plane, this route typically takes 13h 15m.

  • When did momondo last update prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Guayaquil?

Best airlines flying from San Francisco to Guayaquil

Compare and see reviews for airlines that fly from San Francisco to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $203Free CancellationRating
7.2
2,897 reviews
Search JetBlue flights
AviancaPriceFrom $352Free CancellationRating
6.5
2,498 reviews
Search Avianca flights
Copa AirlinesPriceFrom $419Free CancellationRating
7.5
1,565 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $486Free CancellationRating
7.4
9,406 reviews
Search United Airlines flights
American AirlinesPriceFrom $570Free CancellationRating
7.1
11,400 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Guayaquil for you.

Can I find flights from San Francisco to Guayaquil with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guayaquil from San Francisco with this policy.

How can momondo help me find flights from San Francisco to Guayaquil?

Once you have performed a search for San Francisco to Guayaquil flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Guayaquil right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guayaquil from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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