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Cheap flights from San Francisco to Guayaquil from $249

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
7:14 pm - 5:35 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
19h 21m2 stops Las Vegas Harry Reid Intl Panama City Tocumen Intl
Multiple Airlines Logo
12:25 pm - 11:12 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
13h 47m1 stop Panama City Tocumen Intl
$581Multiple Airlines
Wed, Nov 11 - Sun, Nov 15
Avianca Logo
1:15 pm - 9:00 amSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
16h 45m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
7:35 pm - 11:55 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
19h 20m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$611Avianca
Fri, Nov 6 - Sun, Nov 15
Avianca Logo
1:15 pm - 9:00 amSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
16h 45m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
7:35 pm - 11:55 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
19h 20m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$611Avianca
Fri, Nov 6 - Sun, Nov 15
Copa Airlines Logo
7:36 pm - 5:38 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
19h 02m1 stop Panama City Tocumen Intl
Copa Airlines Logo
2:44 pm - 5:25 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
29h 41m1 stop Panama City Tocumen Intl
$612Copa Airlines
Tue, Jan 12 - Tue, Jan 19
American Airlines Logo
10:56 pm - 10:33 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
20h 37m1 stop Miami
American Airlines Logo
2:30 pm - 11:09 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
22h 39m1 stop Miami
$624American Airlines
Mon, Mar 8 - Mon, Mar 15
American Airlines Logo
10:56 pm - 9:33 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
20h 37m1 stop Miami
American Airlines Logo
6:05 am - 8:49 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
16h 44m1 stop Miami
$624American Airlines
Mon, Mar 29 - Wed, Apr 7
Copa Airlines Logo
7:36 pm - 8:56 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
22h 20m1 stop Panama City Tocumen Intl
Copa Airlines Logo
12:25 pm - 11:12 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
13h 47m1 stop Panama City Tocumen Intl
$649Copa Airlines
Wed, Nov 11 - Sun, Nov 15
Multiple Airlines Logo
9:14 am - 1:42 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
25h 28m2 stops Los Angeles Panama City Tocumen Intl
Multiple Airlines Logo
6:38 pm - 11:12 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
31h 34m1 stop Panama City Tocumen Intl
$689Multiple Airlines
Thu, Nov 5 - Sat, Nov 14
United Airlines Logo
5:00 am - 11:40 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
15h 40m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
United Airlines Logo
8:25 am - 9:50 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
28h 25m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$829United Airlines
Wed, Nov 18 - Mon, Nov 23
United Airlines Logo
11:59 pm - 5:35 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
38h 36m2 stops Newark Panama City Tocumen Intl
United Airlines Logo
8:25 am - 7:28 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
26h 03m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$829United Airlines
Sun, Nov 15 - Sun, Nov 22

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Copa Airlines flights from San Francisco to Guayaquil

Our best Copa Airlines deals on San Francisco to Guayaquil flight tickets
Copa Airlines
Jan 12
SFO7:36 pmSan Francisco
19h 02m
1 stop
GYE5:38 pmGuayaquil Jose Joaquin de Olmedo
Jan 19
GYE2:44 pmGuayaquil Jose Joaquin de Olmedo
29h 41m
1 stop
SFO5:25 pmSan Francisco
$612
Copa Airlines
Nov 11
SFO7:36 pmSan Francisco
22h 20m
1 stop
GYE8:56 pmGuayaquil Jose Joaquin de Olmedo
Nov 15
GYE12:25 pmGuayaquil Jose Joaquin de Olmedo
13h 47m
1 stop
SFO11:12 pmSan Francisco
$649
Copa Airlines
Nov 17
SFO7:36 pmSan Francisco
18h 59m
1 stop
GYE5:35 pmGuayaquil Jose Joaquin de Olmedo
Nov 24
GYE2:47 pmGuayaquil Jose Joaquin de Olmedo
11h 25m
1 stop
SFO11:12 pmSan Francisco
$654

GOL flights from San Francisco to Guayaquil

Our best GOL deals on San Francisco to Guayaquil flight tickets
GOL
Jan 12
SFO8:00 amSan Francisco
12h 37m
1 stop
GYE11:37 pmGuayaquil Jose Joaquin de Olmedo
Jan 19
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
30h 30m
2 stops
SFO9:30 amSan Francisco
$778
GOL
Dec 7
SFO11:23 pmSan Francisco
21h 29m
2 stops
GYE11:52 pmGuayaquil Jose Joaquin de Olmedo
Dec 15
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
16h 20m
1 stop
SFO7:20 pmSan Francisco
$830

momondo Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Guayaquil that are best for you.

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Route

Depart

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Price

Cheapest round-trip
Quickest round-trip

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Wed 11/11

7:14 pm-5:35 pm

2 stops19h 21m

Guayaquil Jose Joaquin de Olmedo

Sun 11/15

12:25 pm-11:12 pm

1 stop13h 47m

$581

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Fri 11/6

1:15 pm-9:00 am

2 stops16h 45m

Guayaquil Jose Joaquin de Olmedo

Sun 11/15

7:35 pm-11:55 am

2 stops19h 20m

$611

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Fri 11/6

1:15 pm-9:00 am

2 stops16h 45m

Guayaquil Jose Joaquin de Olmedo

Sun 11/15

7:35 pm-11:55 am

2 stops19h 20m

$611

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Tue 1/12

7:36 pm-5:38 pm

1 stop19h 02m

Guayaquil Jose Joaquin de Olmedo

Tue 1/19

2:44 pm-5:25 pm

1 stop29h 41m

$612

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Mon 3/8

10:56 pm-10:33 pm

1 stop20h 37m

Guayaquil Jose Joaquin de Olmedo

Mon 3/15

2:30 pm-11:09 am

1 stop22h 39m

$624

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Mon 3/29

10:56 pm-9:33 pm

1 stop20h 37m

Guayaquil Jose Joaquin de Olmedo

Wed 4/7

6:05 am-8:49 pm

1 stop16h 44m

$624

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Wed 11/11

7:36 pm-8:56 pm

1 stop22h 20m

Guayaquil Jose Joaquin de Olmedo

Sun 11/15

12:25 pm-11:12 pm

1 stop13h 47m

$649

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Thu 11/5

9:14 am-1:42 pm

2 stops25h 28m

Guayaquil Jose Joaquin de Olmedo

Sat 11/14

6:38 pm-11:12 pm

1 stop31h 34m

$689

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Wed 11/18

5:00 am-11:40 pm

2 stops15h 40m

Guayaquil Jose Joaquin de Olmedo

Mon 11/23

8:25 am-9:50 am

2 stops28h 25m

$829

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sun 11/15

11:59 pm-5:35 pm

2 stops38h 36m

Guayaquil Jose Joaquin de Olmedo

Sun 11/22

8:25 am-7:28 am

2 stops26h 03m

$829

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from San Francisco to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Guayaquil?

Prices are currently typical for flights on this route.

Typical prices usually range from $449 to $656.
The lowest price recently found on this route was $581.

What is the cheapest month to fly to Guayaquil?

The month of February is another great option to travel to Guayaquil, with average flight prices from San Francisco averaging around $570.

How far in advance should I book a flight from San Francisco to Guayaquil?

You are more likely to see cheaper flights to Guayaquil from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Guayaquil for around $663 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Guayaquil from San Francisco for as low as $552 on momondo.

Can stopping save me money on San Francisco to Guayaquil flights?

You could potentially save up to 3% on your flight if you consider stops on a San Francisco to Guayaquil flight.

How have San Francisco to Guayaquil flight prices changed over time?

As of October 2026, prices for San Francisco to Guayaquil flights are approximately 5% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Guayaquil (SFO to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Guayaquil

Best Price Found

$249

Fastest flight time

12h 44m

Direct flights

None
The best one-way flight to Guayaquil from San Francisco in the past 72 hours is $249. The best round-trip flight deal from San Francisco to Guayaquil found on momondo in the last 72 hours is $581.
The fastest flight from San Francisco to Guayaquil takes 12h 44m
There are no direct flights from San Francisco to Guayaquil. There are no popular flight routes from San Francisco to Guayaquil.
Search flight deals

Frequently asked questions about flying from San Francisco to Guayaquil

  • How far is San Francisco to Guayaquil Jose Joaquin de Olmedo by plane?

    The straight-line distance from San Francisco to Guayaquil Jose Joaquin de Olmedo is 3868.8 mi. By plane, this route typically takes 12h 44m.

  • When did momondo last update prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Guayaquil?

Best airlines flying from San Francisco to Guayaquil

Compare and see reviews for airlines that fly from San Francisco to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $203Free CancellationRating
7.1
3,044 reviews
Search JetBlue flights
Copa AirlinesPriceFrom $332Free CancellationRating
7.6
1,545 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $344Free CancellationRating
7.4
10,280 reviews
Search United Airlines flights
AviancaPriceFrom $550Free CancellationRating
6.5
2,558 reviews
Search Avianca flights
American AirlinesPriceFrom $570Free CancellationRating
7.0
12,126 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Guayaquil for you.

Can I find flights from San Francisco to Guayaquil with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guayaquil from San Francisco with this policy.

How can momondo help me find flights from San Francisco to Guayaquil?

Once you have performed a search for San Francisco to Guayaquil flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Guayaquil right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guayaquil from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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