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Cheap flights from San Francisco to Guayaquil from $261

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
1:15 pm - 9:00 amSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
16h 45m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
9:15 pm - 12:55 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
17h 40m2 stops Quito Mariscal Sucr San Salvador El Salvador Intl
$759Avianca
Mon, Mar 8 - Mon, Mar 15
Avianca Logo
2:15 pm - 8:55 amSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
16h 40m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
10:05 am - 11:55 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
15h 50m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$759Avianca
Sat, Apr 3 - Sat, Apr 10
Copa Airlines Logo
8:36 pm - 1:40 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
15h 04m1 stop Panama City Tocumen Intl
Copa Airlines Logo
2:47 pm - 5:25 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
29h 38m1 stop Panama City Tocumen Intl
$759Copa Airlines
Thu, Oct 29 - Mon, Nov 2
Avianca Logo
11:55 pm - 5:35 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
15h 40m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
9:10 am - 11:55 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
16h 45m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$759Avianca
Fri, Apr 2 - Sat, Apr 10
Multiple Airlines Logo
6:02 am - 6:25 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
34h 23m3 stops Denver Intl Miami Bogotá El Dorado
Multiple Airlines Logo
6:55 pm - 12:20 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
32h 25m2 stops Miami Denver Intl
$789Multiple Airlines
Thu, Oct 29 - Mon, Nov 2
American Airlines Logo
8:35 am - 11:16 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
11h 41m1 stop Miami
American Airlines Logo
6:00 am - 12:13 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
21h 13m1 stop Miami
$791American Airlines
Mon, Nov 16 - Thu, Dec 3
Copa Airlines Logo
12:33 am - 5:35 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
14h 02m1 stop Panama City Tocumen Intl
Copa Airlines Logo
2:45 pm - 5:25 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
29h 40m1 stop Panama City Tocumen Intl
$792Copa Airlines
Tue, Nov 24 - Wed, Dec 2
Copa Airlines Logo
8:36 pm - 11:15 amSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
12h 39m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:38 pm - 11:12 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
31h 34m1 stop Panama City Tocumen Intl
$829Copa Airlines
Thu, Oct 29 - Mon, Nov 2
United Airlines Logo
7:15 am - 11:37 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
14h 22m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
United Airlines Logo
12:25 pm - 12:19 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
26h 54m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$841United Airlines
Thu, Oct 29 - Mon, Nov 2
United Airlines Logo
6:41 pm - 8:57 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
23h 16m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
United Airlines Logo
8:25 am - 12:45 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
19h 20m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$869United Airlines
Thu, Dec 10 - Sun, Dec 13

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Avianca flights from San Francisco to Guayaquil

Our best Avianca deals on San Francisco to Guayaquil flight tickets
Avianca
Oct 15
SFO2:15 pmSan Francisco
22h 20m
2 stops
GYE2:35 pmGuayaquil Jose Joaquin de Olmedo
Oct 25
GYE7:35 pmGuayaquil Jose Joaquin de Olmedo
19h 20m
2 stops
SFO12:55 pmSan Francisco
$685
Avianca
Oct 15
SFO2:15 pmSan Francisco
22h 20m
2 stops
GYE2:35 pmGuayaquil Jose Joaquin de Olmedo
Oct 25
GYE5:05 pmGuayaquil Jose Joaquin de Olmedo
21h 50m
2 stops
SFO12:55 pmSan Francisco
$735
Avianca
Mar 8
SFO1:15 pmSan Francisco
16h 45m
2 stops
GYE9:00 amGuayaquil Jose Joaquin de Olmedo
Mar 15
GYE9:15 pmGuayaquil Jose Joaquin de Olmedo
17h 40m
2 stops
SFO12:55 pmSan Francisco
$759

American Airlines flights from San Francisco to Guayaquil

Our best American Airlines deals on San Francisco to Guayaquil flight tickets
American Airlines
Mar 8
SFO8:00 amSan Francisco
12h 42m
1 stop
GYE11:42 pmGuayaquil Jose Joaquin de Olmedo
Mar 15
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
17h 05m
1 stop
SFO9:05 pmSan Francisco
$791
American Airlines
Mar 8
SFO11:30 pmSan Francisco
21h 12m
2 stops
GYE11:42 pmGuayaquil Jose Joaquin de Olmedo
Mar 15
GYE2:40 pmGuayaquil Jose Joaquin de Olmedo
22h 11m
1 stop
SFO10:51 amSan Francisco
$795
American Airlines
Dec 7
SFO12:04 pmSan Francisco
23h 27m
1 stop
GYE2:31 pmGuayaquil Jose Joaquin de Olmedo
Dec 16
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
16h 20m
1 stop
SFO7:20 pmSan Francisco
$810

momondo Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Mon 3/8

1:15 pm-9:00 am

2 stops16h 45m

Guayaquil Jose Joaquin de Olmedo

Mon 3/15

9:15 pm-12:55 pm

2 stops17h 40m

$759

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sat 4/3

2:15 pm-8:55 am

2 stops16h 40m

Guayaquil Jose Joaquin de Olmedo

Sat 4/10

10:05 am-11:55 pm

2 stops15h 50m

$759

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Thu 10/29

8:36 pm-1:40 pm

1 stop15h 04m

Guayaquil Jose Joaquin de Olmedo

Mon 11/2

2:47 pm-5:25 pm

1 stop29h 38m

$759
Quickest round-trip

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Fri 4/2

11:55 pm-5:35 pm

2 stops15h 40m

Guayaquil Jose Joaquin de Olmedo

Sat 4/10

9:10 am-11:55 pm

2 stops16h 45m

$759

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Thu 10/29

6:02 am-6:25 pm

3 stops34h 23m

Guayaquil Jose Joaquin de Olmedo

Mon 11/2

6:55 pm-12:20 am

2 stops32h 25m

$789

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Mon 11/16

8:35 am-11:16 pm

1 stop11h 41m

Guayaquil Jose Joaquin de Olmedo

Thu 12/3

6:00 am-12:13 am

1 stop21h 13m

$791

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Tue 11/24

12:33 am-5:35 pm

1 stop14h 02m

Guayaquil Jose Joaquin de Olmedo

Wed 12/2

2:45 pm-5:25 pm

1 stop29h 40m

$792

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Thu 10/29

8:36 pm-11:15 am

1 stop12h 39m

Guayaquil Jose Joaquin de Olmedo

Mon 11/2

6:38 pm-11:12 pm

1 stop31h 34m

$829

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Thu 10/29

7:15 am-11:37 pm

2 stops14h 22m

Guayaquil Jose Joaquin de Olmedo

Mon 11/2

12:25 pm-12:19 pm

2 stops26h 54m

$841

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Thu 12/10

6:41 pm-8:57 pm

2 stops23h 16m

Guayaquil Jose Joaquin de Olmedo

Sun 12/13

8:25 am-12:45 am

2 stops19h 20m

$869

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from San Francisco to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Guayaquil?

Prices are currently high for flights on this route.

Typical prices usually range from $453 to $619.
The lowest price recently found on this route was $759.

What is the cheapest month to fly to Guayaquil?

The month of November is another great option to travel to Guayaquil, with average flight prices from San Francisco averaging around $572.

Can stopping save me money on San Francisco to Guayaquil flights?

You could potentially save up to 3% on your flight if you consider stops on a San Francisco to Guayaquil flight.

How have San Francisco to Guayaquil flight prices changed over time?

As of October 2026, prices for San Francisco to Guayaquil flights are approximately 147% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Guayaquil (SFO to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Guayaquil

Best Price Found

$261

Fastest flight time

13h 26m

Direct flights

None
The best one-way flight to Guayaquil from San Francisco in the past 72 hours is $261. The best round-trip flight deal from San Francisco to Guayaquil found on momondo in the last 72 hours is $759.
The fastest flight from San Francisco to Guayaquil takes 13h 26m
There are no direct flights from San Francisco to Guayaquil. There are no popular flight routes from San Francisco to Guayaquil.
Search flight deals

Frequently asked questions about flying from San Francisco to Guayaquil

  • How far is San Francisco to Guayaquil Jose Joaquin de Olmedo by plane?

    The straight-line distance from San Francisco to Guayaquil Jose Joaquin de Olmedo is 3868.8 mi. By plane, this route typically takes 13h 26m.

  • When did momondo last update prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Guayaquil?

Best airlines flying from San Francisco to Guayaquil

Compare and see reviews for airlines that fly from San Francisco to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $203Free CancellationRating
7.1
3,053 reviews
Search JetBlue flights
Copa AirlinesPriceFrom $332Free CancellationRating
7.6
1,549 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $344Free CancellationRating
7.4
10,365 reviews
Search United Airlines flights
AviancaPriceFrom $609Free CancellationRating
6.5
2,553 reviews
Search Avianca flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Guayaquil for you.

Can I find flights from San Francisco to Guayaquil with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guayaquil from San Francisco with this policy.

How can momondo help me find flights from San Francisco to Guayaquil?

Once you have performed a search for San Francisco to Guayaquil flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Guayaquil right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guayaquil from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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