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Cheap flights from San Francisco to Guayaquil from $300

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Guayaquil departing on 8/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
8:21 pm - 12:01 am
SFO
-
GYE
25h 40m
1 stop
Copa Airlines Logo
6:40 pm - 6:25 pm
GYE
-
SFO
25h 45m
1 stop
$555Copa Airlines
Thu, Oct 22 - Wed, Oct 28
Copa Airlines Logo
8:21 pm - 12:01 am
SFO
-
GYE
25h 40m
1 stop
Copa Airlines Logo
8:25 am - 11:40 pm
GYE
-
SFO
17h 15m
1 stop
$578Copa Airlines
Thu, Oct 15 - Sun, Oct 25
Copa Airlines Logo
8:16 pm - 11:38 pm
SFO
-
GYE
25h 22m
1 stop
Copa Airlines Logo
4:12 am - 5:59 pm
GYE
-
SFO
15h 47m
1 stop
$580Copa Airlines
Tue, Jul 14 - Wed, Jul 22
Avianca Logo
11:55 pm - 5:35 pm
SFO
-
GYE
15h 40m
2 stops
Avianca Logo
10:25 am - 10:50 pm
GYE
-
SFO
14h 25m
2 stops
$619Avianca
Thu, Oct 15 - Sun, Oct 25
Avianca Logo
11:55 pm - 11:30 pm
SFO
-
GYE
21h 35m
2 stops
Avianca Logo
3:45 pm - 12:50 pm
GYE
-
SFO
23h 05m
2 stops
$626Avianca
Tue, Jul 14 - Wed, Jul 22
Avianca Logo
2:15 pm - 7:30 am
SFO
-
GYE
15h 15m
2 stops
Avianca Logo
10:05 am - 10:35 pm
GYE
-
SFO
14h 30m
2 stops
$639Avianca
Fri, Jul 24 - Mon, Jul 27
Avianca Logo
1:20 pm - 5:45 pm
SFO
-
GYE
25h 25m
2 stops
Avianca Logo
4:40 am - 10:40 pm
GYE
-
SFO
21h 00m
2 stops
$653Avianca
Thu, Nov 5 - Fri, Nov 13
Avianca Logo
2:30 am - 8:55 am
SFO
-
GYE
28h 25m
2 stops
Avianca Logo
6:50 pm - 10:35 pm
GYE
-
SFO
29h 45m
2 stops
$669Avianca
Sat, Jun 27 - Mon, Jul 6
Copa Airlines Logo
8:16 pm - 11:38 pm
SFO
-
GYE
25h 22m
1 stop
Copa Airlines Logo
6:27 pm - 6:00 pm
GYE
-
SFO
25h 33m
1 stop
$670Copa Airlines
Fri, Jul 24 - Mon, Jul 27
Avianca Logo
2:30 am - 11:30 pm
SFO
-
GYE
19h 00m
2 stops
Avianca Logo
9:10 am - 11:55 pm
GYE
-
SFO
16h 45m
2 stops
$679Avianca
Tue, Jul 21 - Sat, Aug 1

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GOL flights from San Francisco to Guayaquil

Our best GOL deals on San Francisco to Guayaquil flight tickets
GOL
Jul 23
SFO12:26 amSan Francisco
20h 11m
2 stops
GYE10:37 pmGuayaquil Jose Joaquin de Olmedo
Jul 27
GYE2:25 pmGuayaquil Jose Joaquin de Olmedo
21h 59m
1 stop
SFO10:24 amSan Francisco
$689
GOL
Nov 6
SFO3:09 pmSan Francisco
20h 18m
2 stops
GYE2:27 pmGuayaquil Jose Joaquin de Olmedo
Nov 15
GYE3:30 pmGuayaquil Jose Joaquin de Olmedo
22h 38m
1 stop
SFO11:08 amSan Francisco
$702
GOL
Jun 17
SFO12:21 pmSan Francisco
23h 10m
2 stops
GYE1:31 pmGuayaquil Jose Joaquin de Olmedo
Jun 25
GYE6:01 amGuayaquil Jose Joaquin de Olmedo
19h 43m
1 stop
SFO11:44 pmSan Francisco
$752

JetBlue flights from San Francisco to Guayaquil

Our best JetBlue deals on San Francisco to Guayaquil flight tickets
JetBlue
Jul 7
SFO8:35 pmSan Francisco
15h 52m
1 stop
GYE2:27 pmGuayaquil Jose Joaquin de Olmedo
Jul 21
GYE1:27 pmGuayaquil Jose Joaquin de Olmedo
12h 24m
1 stop
SFO11:51 pmSan Francisco
$744
JetBlue
Jul 24
SFO10:40 pmSan Francisco
14h 42m
1 stop
GYE3:22 pmGuayaquil Jose Joaquin de Olmedo
Jul 27
GYE1:27 pmGuayaquil Jose Joaquin de Olmedo
12h 24m
1 stop
SFO11:51 pmSan Francisco
$758
JetBlue
Jul 24
SFO10:40 pmSan Francisco
14h 42m
1 stop
GYE3:22 pmGuayaquil Jose Joaquin de Olmedo
Jul 27
GYE1:27 pmGuayaquil Jose Joaquin de Olmedo
22h 21m
1 stop
SFO9:48 amSan Francisco
$774

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated June 15, 2026.
Use the filters below to find and compare flights from San Francisco to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Thu 10/22

8:21 pm-12:01 am

1 stop25h 40m

Guayaquil Jose Joaquin de Olmedo

Wed 10/28

6:40 pm-6:25 pm

1 stop25h 45m

$555

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Thu 10/15

8:21 pm-12:01 am

1 stop25h 40m

Guayaquil Jose Joaquin de Olmedo

Sun 10/25

8:25 am-11:40 pm

1 stop17h 15m

$578

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Tue 7/14

8:16 pm-11:38 pm

1 stop25h 22m

Guayaquil Jose Joaquin de Olmedo

Wed 7/22

4:12 am-5:59 pm

1 stop15h 47m

$580

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Thu 10/15

11:55 pm-5:35 pm

2 stops15h 40m

Guayaquil Jose Joaquin de Olmedo

Sun 10/25

10:25 am-10:50 pm

2 stops14h 25m

$619

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Tue 7/14

11:55 pm-11:30 pm

2 stops21h 35m

Guayaquil Jose Joaquin de Olmedo

Wed 7/22

3:45 pm-12:50 pm

2 stops23h 05m

$626
Quickest round-trip

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Fri 7/24

2:15 pm-7:30 am

2 stops15h 15m

Guayaquil Jose Joaquin de Olmedo

Mon 7/27

10:05 am-10:35 pm

2 stops14h 30m

$639

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Thu 11/5

1:20 pm-5:45 pm

2 stops25h 25m

Guayaquil Jose Joaquin de Olmedo

Fri 11/13

4:40 am-10:40 pm

2 stops21h 00m

$653

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Sat 6/27

2:30 am-8:55 am

2 stops28h 25m

Guayaquil Jose Joaquin de Olmedo

Mon 7/6

6:50 pm-10:35 pm

2 stops29h 45m

$669

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Fri 7/24

8:16 pm-11:38 pm

1 stop25h 22m

Guayaquil Jose Joaquin de Olmedo

Mon 7/27

6:27 pm-6:00 pm

1 stop25h 33m

$670

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Tue 7/21

2:30 am-11:30 pm

2 stops19h 00m

Guayaquil Jose Joaquin de Olmedo

Sat 8/1

9:10 am-11:55 pm

2 stops16h 45m

$679

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from San Francisco to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Guayaquil?

What is the cheapest month to fly to Guayaquil?

The month of September is another great option to travel to Guayaquil, with average flight prices from San Francisco averaging around $492.

How far in advance should I book a flight from San Francisco to Guayaquil?

You are more likely to see cheaper flights to Guayaquil from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Guayaquil for around $629 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Guayaquil from San Francisco for as low as $484 on momondo.

Can stopping save me money on San Francisco to Guayaquil flights?

You could potentially save up to 34% on your flight if you consider stops on a San Francisco to Guayaquil flight.

How have San Francisco to Guayaquil flight prices changed over time?

As of June 2026, prices for San Francisco to Guayaquil flights are approximately 29% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Guayaquil (SFO to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Guayaquil

Fastest flight time

16h 55m

Direct flights

None
The fastest flight from San Francisco to Guayaquil takes 16h 55m
There are no direct flights from San Francisco to Guayaquil. There are no popular flight routes from San Francisco to Guayaquil.
Search flight deals

Frequently asked questions about flying from San Francisco to Guayaquil

  • How far is San Francisco to Guayaquil Jose Joaquin de Olmedo by plane?

    The straight-line distance from San Francisco to Guayaquil Jose Joaquin de Olmedo is 3868.8 mi. By plane, this route typically takes 16h 55m.

  • When did momondo last update prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Guayaquil?

Best airlines flying from San Francisco to Guayaquil

Compare and see reviews for airlines that fly from San Francisco to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $203Free CancellationRating
7.1
2,984 reviews
Search JetBlue flights
Copa AirlinesPriceFrom $279Free CancellationRating
7.5
1,568 reviews
Search Copa Airlines flights
AviancaPriceFrom $472Free CancellationRating
6.5
2,532 reviews
Search Avianca flights
United AirlinesPriceFrom $486Free CancellationRating
7.4
9,827 reviews
Search United Airlines flights
American AirlinesPriceFrom $570Free CancellationRating
7.1
11,662 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Guayaquil for you.

Can I find flights from San Francisco to Guayaquil with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guayaquil from San Francisco with this policy.

How can momondo help me find flights from San Francisco to Guayaquil?

Once you have performed a search for San Francisco to Guayaquil flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Guayaquil right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guayaquil from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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