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Cheap flights from San Francisco to Guayaquil from $296

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Guayaquil departing on 7/20. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Francisco to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
1:12 am - 8:52 pm
SFO
-
GYE
17h 40m
1 stop
Copa Airlines Logo
4:29 am - 11:40 pm
GYE
-
SFO
21h 11m
1 stop
$512Copa Airlines
Tue, Sep 1 - Tue, Sep 15
American Airlines Logo
7:30 am - 10:45 pm
SFO
-
GYE
13h 15m
1 stop
American Airlines Logo
8:20 am - 8:34 am
GYE
-
SFO
26h 14m
2 stops
$528American Airlines
Wed, Sep 2 - Tue, Sep 15
GOL Logo
7:36 pm - 6:55 pm
SFO
-
GYE
21h 19m
2 stops
GOL Logo
8:25 am - 6:41 pm
GYE
-
SFO
12h 16m
1 stop
$531GOL
Thu, Oct 8 - Tue, Oct 13
Copa Airlines Logo
1:12 am - 1:33 pm
SFO
-
GYE
10h 21m
1 stop
Copa Airlines Logo
8:34 am - 6:10 pm
GYE
-
SFO
11h 36m
1 stop
$558Copa Airlines
Wed, Oct 14 - Sun, Oct 25
GOL Logo
1:29 pm - 1:33 pm
SFO
-
GYE
22h 04m
2 stops
GOL Logo
2:30 pm - 8:46 am
GYE
-
SFO
20h 16m
2 stops
$561GOL
Sun, Oct 4 - Thu, Oct 15
Copa Airlines Logo
1:12 am - 1:35 pm
SFO
-
GYE
10h 23m
1 stop
Copa Airlines Logo
4:29 am - 11:40 pm
GYE
-
SFO
21h 11m
1 stop
$586Copa Airlines
Thu, Aug 20 - Fri, Sep 11
American Airlines Logo
9:20 pm - 7:00 pm
SFO
-
GYE
19h 40m
2 stops
American Airlines Logo
8:20 am - 8:34 am
GYE
-
SFO
26h 14m
2 stops
$588American Airlines
Sat, Sep 19 - Sat, Sep 26
Copa Airlines Logo
1:12 am - 1:34 pm
SFO
-
GYE
10h 22m
1 stop
Copa Airlines Logo
4:29 am - 11:40 pm
GYE
-
SFO
21h 11m
1 stop
$609Copa Airlines
Fri, Sep 18 - Sat, Sep 26
Avianca Logo
2:15 pm - 8:55 am
SFO
-
GYE
16h 40m
2 stops
Avianca Logo
8:50 pm - 1:00 pm
GYE
-
SFO
18h 10m
2 stops
$619Avianca
Thu, Oct 15 - Sun, Oct 25
GOL Logo
11:59 pm - 1:33 pm
SFO
-
GYE
11h 34m
1 stop
GOL Logo
8:25 am - 6:41 pm
GYE
-
SFO
12h 16m
1 stop
$652GOL
Thu, Oct 8 - Tue, Oct 13

Copa Airlines flights from San Francisco to Guayaquil

Our best Copa Airlines deals on San Francisco to Guayaquil flight tickets
Copa Airlines
Sep 1
SFO1:12 amSan Francisco
17h 40m
1 stop
GYE8:52 pmGuayaquil Jose Joaquin de Olmedo
Sep 15
GYE4:29 amGuayaquil Jose Joaquin de Olmedo
21h 11m
1 stop
SFO11:40 pmSan Francisco
$512
Copa Airlines
Oct 14
SFO1:12 amSan Francisco
10h 21m
1 stop
GYE1:33 pmGuayaquil Jose Joaquin de Olmedo
Oct 25
GYE8:34 amGuayaquil Jose Joaquin de Olmedo
11h 36m
1 stop
SFO6:10 pmSan Francisco
$558
Copa Airlines
Aug 20
SFO1:12 amSan Francisco
10h 23m
1 stop
GYE1:35 pmGuayaquil Jose Joaquin de Olmedo
Sep 11
GYE4:29 amGuayaquil Jose Joaquin de Olmedo
21h 11m
1 stop
SFO11:40 pmSan Francisco
$586

Avianca flights from San Francisco to Guayaquil

Our best Avianca deals on San Francisco to Guayaquil flight tickets
Avianca
Oct 15
SFO2:15 pmSan Francisco
16h 40m
2 stops
GYE8:55 amGuayaquil Jose Joaquin de Olmedo
Oct 25
GYE8:50 pmGuayaquil Jose Joaquin de Olmedo
18h 10m
2 stops
SFO1:00 pmSan Francisco
$619
Avianca
May 18
SFO11:55 pmSan Francisco
15h 40m
2 stops
GYE5:35 pmGuayaquil Jose Joaquin de Olmedo
Jun 3
GYE9:35 pmGuayaquil Jose Joaquin de Olmedo
17h 15m
2 stops
SFO12:50 pmSan Francisco
$639
Avianca
May 18
SFO2:15 pmSan Francisco
16h 55m
2 stops
GYE9:10 amGuayaquil Jose Joaquin de Olmedo
Jun 3
GYE8:55 pmGuayaquil Jose Joaquin de Olmedo
17h 55m
2 stops
SFO12:50 pmSan Francisco
$659

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from San Francisco to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Tue 9/1

1:12 am-8:52 pm

1 stop17h 40m

Guayaquil Jose Joaquin de Olmedo

Tue 9/15

4:29 am-11:40 pm

1 stop21h 11m

$512

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Wed 9/2

7:30 am-10:45 pm

1 stop13h 15m

Guayaquil Jose Joaquin de Olmedo

Tue 9/15

8:20 am-8:34 am

2 stops26h 14m

$528

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Thu 10/8

7:36 pm-6:55 pm

2 stops21h 19m

Guayaquil Jose Joaquin de Olmedo

Tue 10/13

8:25 am-6:41 pm

1 stop12h 16m

$531
Quickest round-trip

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Wed 10/14

1:12 am-1:33 pm

1 stop10h 21m

Guayaquil Jose Joaquin de Olmedo

Sun 10/25

8:34 am-6:10 pm

1 stop11h 36m

$558

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Sun 10/4

1:29 pm-1:33 pm

2 stops22h 04m

Guayaquil Jose Joaquin de Olmedo

Thu 10/15

2:30 pm-8:46 am

2 stops20h 16m

$561

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Thu 8/20

1:12 am-1:35 pm

1 stop10h 23m

Guayaquil Jose Joaquin de Olmedo

Fri 9/11

4:29 am-11:40 pm

1 stop21h 11m

$586

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Sat 9/19

9:20 pm-7:00 pm

2 stops19h 40m

Guayaquil Jose Joaquin de Olmedo

Sat 9/26

8:20 am-8:34 am

2 stops26h 14m

$588

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Fri 9/18

1:12 am-1:34 pm

1 stop10h 22m

Guayaquil Jose Joaquin de Olmedo

Sat 9/26

4:29 am-11:40 pm

1 stop21h 11m

$609

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Thu 10/15

2:15 pm-8:55 am

2 stops16h 40m

Guayaquil Jose Joaquin de Olmedo

Sun 10/25

8:50 pm-1:00 pm

2 stops18h 10m

$619

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Thu 10/8

11:59 pm-1:33 pm

1 stop11h 34m

Guayaquil Jose Joaquin de Olmedo

Tue 10/13

8:25 am-6:41 pm

1 stop12h 16m

$652

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from San Francisco to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Guayaquil?

What is the cheapest month to fly to Guayaquil?

The month of February is another great option to travel to Guayaquil, with average flight prices from San Francisco averaging around $527.

How far in advance should I book a flight from San Francisco to Guayaquil?

You are more likely to see cheaper flights to Guayaquil from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Guayaquil for around $636 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Guayaquil from San Francisco for as low as $484 on momondo.

Can stopping save me money on San Francisco to Guayaquil flights?

You could potentially save up to 26% on your flight if you consider stops on a San Francisco to Guayaquil flight.

How have San Francisco to Guayaquil flight prices changed over time?

As of May 2026, prices for San Francisco to Guayaquil flights are approximately 77% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Guayaquil (SFO to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Guayaquil

Fastest flight time

13h 00m

Direct flights

None
The fastest flight from San Francisco to Guayaquil takes 13h 00m
There are no direct flights from San Francisco to Guayaquil. There are no popular flight routes from San Francisco to Guayaquil.
Search flight deals

Frequently asked questions about flying from San Francisco to Guayaquil

  • How far is San Francisco to Guayaquil Jose Joaquin de Olmedo by plane?

    The straight-line distance from San Francisco to Guayaquil Jose Joaquin de Olmedo is 3868.8 mi. By plane, this route typically takes 13h 00m.

  • When did momondo last update prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Guayaquil?

Best airlines flying from San Francisco to Guayaquil

Compare and see reviews for airlines that fly from San Francisco to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $203Free CancellationRating
7.1
2,971 reviews
Search JetBlue flights
Copa AirlinesPriceFrom $332Free CancellationRating
7.5
1,584 reviews
Search Copa Airlines flights
AviancaPriceFrom $352Free CancellationRating
6.5
2,523 reviews
Search Avianca flights
United AirlinesPriceFrom $486Free CancellationRating
7.4
9,707 reviews
Search United Airlines flights
American AirlinesPriceFrom $570Free CancellationRating
7.1
11,666 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Guayaquil for you.

Can I find flights from San Francisco to Guayaquil with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guayaquil from San Francisco with this policy.

How can momondo help me find flights from San Francisco to Guayaquil?

Once you have performed a search for San Francisco to Guayaquil flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Guayaquil right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guayaquil from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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