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Cheap flights from San Francisco to Guayaquil from $176

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Francisco to Guayaquil departing on 4/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Francisco to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
11:59 pm - 2:26 pm
SFO
-
GYE
12h 27m
1 stop
JetBlue Logo
12:25 pm - 11:56 pm
GYE
-
SFO
13h 31m
1 stop
$432JetBlue
Mon, Apr 13 - Wed, Apr 29
Avianca Logo
11:55 pm - 5:35 pm
SFO
-
GYE
15h 40m
2 stops
Avianca Logo
9:10 am - 11:55 pm
GYE
-
SFO
16h 45m
2 stops
$444Avianca
Mon, May 25 - Thu, May 28
Avianca Logo
2:15 pm - 8:55 am
SFO
-
GYE
16h 40m
2 stops
Avianca Logo
8:55 pm - 12:50 pm
GYE
-
SFO
17h 55m
2 stops
$450Avianca
Mon, Apr 13 - Wed, Apr 29
JetBlue Logo
3:20 pm - 10:34 am
SFO
-
GYE
17h 14m
1 stop
JetBlue Logo
12:25 pm - 11:09 am
GYE
-
SFO
24h 44m
1 stop
$455JetBlue
Tue, Apr 7 - Tue, Apr 14
Multiple Airlines Logo
11:55 pm - 5:35 pm
SFO
-
GYE
15h 40m
2 stops
Multiple Airlines Logo
12:25 pm - 11:56 pm
GYE
-
SFO
13h 31m
1 stop
$456Multiple Airlines
Mon, Apr 13 - Wed, Apr 29
Avianca Logo
11:55 pm - 5:35 pm
SFO
-
GYE
15h 40m
2 stops
Avianca Logo
3:30 am - 10:35 pm
GYE
-
SFO
21h 05m
2 stops
$462Avianca
Mon, May 25 - Thu, May 28
Avianca Logo
2:15 pm - 8:55 am
SFO
-
GYE
16h 40m
2 stops
Avianca Logo
6:50 pm - 11:55 pm
GYE
-
SFO
31h 05m
2 stops
$473Avianca
Tue, May 26 - Wed, May 27
JetBlue Logo
3:31 pm - 10:58 am
SFO
-
GYE
17h 27m
1 stop
JetBlue Logo
3:51 pm - 9:23 am
GYE
-
SFO
19h 32m
1 stop
$481JetBlue
Sat, May 2 - Mon, May 11
Avianca Logo
11:55 pm - 7:30 am
SFO
-
GYE
29h 35m
2 stops
Avianca Logo
6:50 pm - 11:55 pm
GYE
-
SFO
31h 05m
2 stops
$482Avianca
Sat, May 2 - Mon, May 11
JetBlue Logo
11:59 pm - 2:26 pm
SFO
-
GYE
12h 27m
1 stop
JetBlue Logo
12:25 pm - 11:56 pm
GYE
-
SFO
13h 31m
1 stop
$485JetBlue
Mon, Apr 13 - Fri, Apr 17

Avianca flights from San Francisco to Guayaquil

Our best Avianca deals on San Francisco to Guayaquil flight tickets
Avianca
May 25
SFO11:55 pmSan Francisco
15h 40m
2 stops
GYE5:35 pmGuayaquil Jose Joaquin de Olmedo
May 28
GYE9:10 amGuayaquil Jose Joaquin de Olmedo
16h 45m
2 stops
SFO11:55 pmSan Francisco
$444
Avianca
Apr 13
SFO2:15 pmSan Francisco
16h 40m
2 stops
GYE8:55 amGuayaquil Jose Joaquin de Olmedo
Apr 29
GYE8:55 pmGuayaquil Jose Joaquin de Olmedo
17h 55m
2 stops
SFO12:50 pmSan Francisco
$450
Avianca
May 25
SFO11:55 pmSan Francisco
15h 40m
2 stops
GYE5:35 pmGuayaquil Jose Joaquin de Olmedo
May 27
GYE6:50 pmGuayaquil Jose Joaquin de Olmedo
20h 00m
2 stops
SFO12:50 pmSan Francisco
$462

American Airlines flights from San Francisco to Guayaquil

Our best American Airlines deals on San Francisco to Guayaquil flight tickets
American Airlines
May 24
SFO11:58 pmSan Francisco
11h 33m
1 stop
GYE1:31 pmGuayaquil Jose Joaquin de Olmedo
May 28
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
19h 59m
1 stop
SFO11:59 pmSan Francisco
$495
American Airlines
May 24
SFO6:08 pmSan Francisco
17h 23m
2 stops
GYE1:31 pmGuayaquil Jose Joaquin de Olmedo
May 28
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
19h 59m
1 stop
SFO11:59 pmSan Francisco
$500
American Airlines
Mar 4
SFO1:20 pmSan Francisco
22h 10m
1 stop
GYE2:30 pmGuayaquil Jose Joaquin de Olmedo
Mar 11
GYE6:12 amGuayaquil Jose Joaquin de Olmedo
19h 47m
1 stop
SFO11:59 pmSan Francisco
$526

momondo Fare Finder

 
Customize your flight search to find flights from San Francisco to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 2, 2026.
Use the filters below to find and compare flights from San Francisco to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 4/13

11:59 pm-2:26 pm

1 stop12h 27m

Guayaquil Jose Joaquin de Olmedo

Wed 4/29

12:25 pm-11:56 pm

1 stop13h 31m

$432

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 5/25

11:55 pm-5:35 pm

2 stops15h 40m

Guayaquil Jose Joaquin de Olmedo

Thu 5/28

9:10 am-11:55 pm

2 stops16h 45m

$444

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 4/13

2:15 pm-8:55 am

2 stops16h 40m

Guayaquil Jose Joaquin de Olmedo

Wed 4/29

8:55 pm-12:50 pm

2 stops17h 55m

$450

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Tue 4/7

3:20 pm-10:34 am

1 stop17h 14m

Guayaquil Jose Joaquin de Olmedo

Tue 4/14

12:25 pm-11:09 am

1 stop24h 44m

$455

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 4/13

11:55 pm-5:35 pm

2 stops15h 40m

Guayaquil Jose Joaquin de Olmedo

Wed 4/29

12:25 pm-11:56 pm

1 stop13h 31m

$456

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 5/25

11:55 pm-5:35 pm

2 stops15h 40m

Guayaquil Jose Joaquin de Olmedo

Thu 5/28

3:30 am-10:35 pm

2 stops21h 05m

$462

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Tue 5/26

2:15 pm-8:55 am

2 stops16h 40m

Guayaquil Jose Joaquin de Olmedo

Wed 5/27

6:50 pm-11:55 pm

2 stops31h 05m

$473

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Sat 5/2

3:31 pm-10:58 am

1 stop17h 27m

Guayaquil Jose Joaquin de Olmedo

Mon 5/11

3:51 pm-9:23 am

1 stop19h 32m

$481

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Sat 5/2

11:55 pm-7:30 am

2 stops29h 35m

Guayaquil Jose Joaquin de Olmedo

Mon 5/11

6:50 pm-11:55 pm

2 stops31h 05m

$482

San FranciscoGuayaquil

SFO - GYE

SFOGYE

San Francisco

Mon 4/13

11:59 pm-2:26 pm

1 stop12h 27m

Guayaquil Jose Joaquin de Olmedo

Fri 4/17

12:25 pm-11:56 pm

1 stop13h 31m

$485

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from San Francisco to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Guayaquil?

The month of October is another great option to travel to Guayaquil, with average flight prices from San Francisco averaging around $519.

How far in advance should I book a flight to Guayaquil?

You are more likely to see cheaper flights to Guayaquil from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Guayaquil for around $640 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Guayaquil from San Francisco for as low as $459 on momondo.

Can stopping save me money on San Francisco to Guayaquil flights?

You could potentially save up to 6% on your flight if you consider stops on a San Francisco to Guayaquil flight.

How have San Francisco to Guayaquil flight prices changed over time?

As of March 2026, prices for San Francisco to Guayaquil flights are approximately 16% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Guayaquil (SFO to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Guayaquil

Fastest flight time

13h 39m

Direct flights

None
The fastest flight from San Francisco to Guayaquil takes 13h 39m
There are no direct flights from San Francisco to Guayaquil. There are no popular flight routes from San Francisco to Guayaquil.
Search flight deals

  • How far is San Francisco to Guayaquil Jose Joaquin de Olmedo by plane?

    The straight-line distance from San Francisco to Guayaquil Jose Joaquin de Olmedo is 3869.7 mi. By plane, this route typically takes 13h 39m.

  • When did momondo last update prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Guayaquil?

Best airlines flying from San Francisco to Guayaquil

Compare and see reviews for airlines that fly from San Francisco to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $203Free CancellationRating
7.2
2,894 reviews
Search JetBlue flights
AviancaPriceFrom $352Free CancellationRating
6.5
2,496 reviews
Search Avianca flights
Copa AirlinesPriceFrom $419Free CancellationRating
7.5
1,559 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $486Free CancellationRating
7.4
9,372 reviews
Search United Airlines flights
American AirlinesPriceFrom $570Free CancellationRating
7.1
11,370 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Guayaquil for you.

Can I find flights from San Francisco to Guayaquil with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guayaquil from San Francisco with this policy.

How can momondo help me find flights from San Francisco to Guayaquil?

Once you have performed a search for San Francisco to Guayaquil flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Guayaquil right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guayaquil from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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