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Cheap flights from San Francisco to Guayaquil from $226

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from San Francisco to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
2:18 pm - 12:05 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
19h 47m1 stop New York John F Kennedy Intl
JetBlue Logo
4:55 pm - 10:49 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
19h 54m1 stop New York John F Kennedy Intl
$532JetBlue
Tue, Oct 13 - Tue, Oct 20
JetBlue Logo
8:44 pm - 12:05 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
13h 21m1 stop New York John F Kennedy Intl
JetBlue Logo
4:55 pm - 9:25 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
18h 30m1 stop New York John F Kennedy Intl
$544JetBlue
Sat, Oct 10 - Mon, Oct 19
Copa Airlines Logo
7:36 pm - 5:35 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
18h 59m1 stop Panama City Tocumen Intl
Copa Airlines Logo
6:38 pm - 5:25 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
25h 47m1 stop Panama City Tocumen Intl
$572Copa Airlines
Sun, Nov 15 - Sat, Nov 21
Copa Airlines Logo
7:36 pm - 5:35 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
18h 59m1 stop Panama City Tocumen Intl
Copa Airlines Logo
5:58 am - 11:12 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
20h 14m1 stop Panama City Tocumen Intl
$572Copa Airlines
Sun, Nov 15 - Sat, Nov 21
Multiple Airlines Logo
7:59 pm - 10:33 amSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
36h 34m2 stops Las Vegas Harry Reid Intl Panama City Tocumen Intl
Multiple Airlines Logo
8:23 am - 11:40 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
17h 17m1 stop Panama City Tocumen Intl
$594Multiple Airlines
Sun, Oct 18 - Sun, Oct 25
Multiple Airlines Logo
7:11 pm - 1:33 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
16h 22m2 stops Las Vegas Harry Reid Intl Panama City Tocumen Intl
Multiple Airlines Logo
11:44 am - 11:40 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
13h 56m1 stop Panama City Tocumen Intl
$596Multiple Airlines
Tue, Oct 13 - Tue, Oct 20
American Airlines Logo
5:22 pm - 2:34 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
18h 12m2 stops Chicago O'Hare Intl Miami
American Airlines Logo
6:00 am - 12:58 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
21h 58m1 stop Miami
$609American Airlines
Sun, Nov 15 - Sat, Nov 21
American Airlines Logo
5:22 pm - 2:34 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
18h 12m2 stops Chicago O'Hare Intl Miami
American Airlines Logo
3:35 pm - 8:43 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
20h 08m2 stops Miami Los Angeles
$609American Airlines
Sun, Nov 15 - Sat, Nov 21
Avianca Logo
11:55 pm - 5:35 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
15h 40m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
10:05 am - 10:35 pmGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
14h 30m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$658Avianca
Sat, Oct 10 - Mon, Oct 19
Avianca Logo
11:00 pm - 6:25 pmSFO  San Francisco-GYE Guayaquil Jose Joaquin de Olmedo
16h 25m2 stops San Salvador El Salvador Intl Bogotá El Dorado
Avianca Logo
7:35 pm - 11:55 amGYE  Guayaquil Jose Joaquin de Olmedo-SFO San Francisco
19h 20m2 stops Bogotá El Dorado San Salvador El Salvador Intl
$659Avianca
Wed, Nov 4 - Sun, Nov 8

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GOL flights from San Francisco to Guayaquil

Our best GOL deals on San Francisco to Guayaquil flight tickets
GOL
Nov 5
SFO1:57 pmSan Francisco
21h 37m
2 stops
GYE2:34 pmGuayaquil Jose Joaquin de Olmedo
Nov 9
GYE3:34 pmGuayaquil Jose Joaquin de Olmedo
21h 06m
2 stops
SFO9:40 amSan Francisco
$654
GOL
Nov 9
SFO12:39 pmSan Francisco
22h 55m
2 stops
GYE2:34 pmGuayaquil Jose Joaquin de Olmedo
Nov 18
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
16h 17m
1 stop
SFO7:17 pmSan Francisco
$657
GOL
Sep 18
SFO11:58 pmSan Francisco
20h 12m
2 stops
GYE10:10 pmGuayaquil Jose Joaquin de Olmedo
Sep 21
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
19h 59m
1 stop
SFO11:59 pmSan Francisco
$1,147

American Airlines flights from San Francisco to Guayaquil

Our best American Airlines deals on San Francisco to Guayaquil flight tickets
American Airlines
Nov 15
SFO5:22 pmSan Francisco
18h 12m
2 stops
GYE2:34 pmGuayaquil Jose Joaquin de Olmedo
Nov 21
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
21h 58m
1 stop
SFO12:58 amSan Francisco
$609
American Airlines
Oct 29
SFO6:00 amSan Francisco
14h 39m
2 stops
GYE10:39 pmGuayaquil Jose Joaquin de Olmedo
Nov 5
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
21h 12m
1 stop
SFO12:12 amSan Francisco
$627
American Airlines
Nov 4
SFO12:04 pmSan Francisco
23h 30m
1 stop
GYE2:34 pmGuayaquil Jose Joaquin de Olmedo
Nov 8
GYE3:34 pmGuayaquil Jose Joaquin de Olmedo
22h 19m
1 stop
SFO10:53 amSan Francisco
$643

momondo Fare Finder

 
Use the filters below to find and compare flights from San Francisco to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Tue 10/13

2:18 pm-12:05 pm

1 stop19h 47m

Guayaquil Jose Joaquin de Olmedo

Tue 10/20

4:55 pm-10:49 am

1 stop19h 54m

$532

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sat 10/10

8:44 pm-12:05 pm

1 stop13h 21m

Guayaquil Jose Joaquin de Olmedo

Mon 10/19

4:55 pm-9:25 am

1 stop18h 30m

$544

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sun 11/15

7:36 pm-5:35 pm

1 stop18h 59m

Guayaquil Jose Joaquin de Olmedo

Sat 11/21

6:38 pm-5:25 pm

1 stop25h 47m

$572

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sun 11/15

7:36 pm-5:35 pm

1 stop18h 59m

Guayaquil Jose Joaquin de Olmedo

Sat 11/21

5:58 am-11:12 pm

1 stop20h 14m

$572

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sun 10/18

7:59 pm-10:33 am

2 stops36h 34m

Guayaquil Jose Joaquin de Olmedo

Sun 10/25

8:23 am-11:40 pm

1 stop17h 17m

$594

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Tue 10/13

7:11 pm-1:33 pm

2 stops16h 22m

Guayaquil Jose Joaquin de Olmedo

Tue 10/20

11:44 am-11:40 pm

1 stop13h 56m

$596

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sun 11/15

5:22 pm-2:34 pm

2 stops18h 12m

Guayaquil Jose Joaquin de Olmedo

Sat 11/21

6:00 am-12:58 am

1 stop21h 58m

$609

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sun 11/15

5:22 pm-2:34 pm

2 stops18h 12m

Guayaquil Jose Joaquin de Olmedo

Sat 11/21

3:35 pm-8:43 am

2 stops20h 08m

$609
Quickest round-trip

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Sat 10/10

11:55 pm-5:35 pm

2 stops15h 40m

Guayaquil Jose Joaquin de Olmedo

Mon 10/19

10:05 am-10:35 pm

2 stops14h 30m

$658

San FranciscoGuayaquil

SFO San Francisco - GYE Guayaquil Jose Joaquin de Olmedo

SFOGYE

San Francisco

Wed 11/4

11:00 pm-6:25 pm

2 stops16h 25m

Guayaquil Jose Joaquin de Olmedo

Sun 11/8

7:35 pm-11:55 am

2 stops19h 20m

$659

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from San Francisco to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between San Francisco and Guayaquil?

Prices are currently typical for flights on this route.

Typical prices usually range from $503 to $855.
The lowest price recently found on this route was $532.

What is the cheapest month to fly to Guayaquil?

The month of February is another great option to travel to Guayaquil, with average flight prices from San Francisco averaging around $570.

How far in advance should I book a flight from San Francisco to Guayaquil?

You are more likely to see cheaper flights to Guayaquil from San Francisco when booking weeks ahead of your departure date. In general, you can expect to find flights to Guayaquil for around $662 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Guayaquil from San Francisco for as low as $552 on momondo.

Can stopping save me money on San Francisco to Guayaquil flights?

You could potentially save up to 57% on your flight if you consider stops on a San Francisco to Guayaquil flight.

How have San Francisco to Guayaquil flight prices changed over time?

As of September 2026, prices for San Francisco to Guayaquil flights are approximately 11% more expensive when compared to flights at the same time last year.

When to book flights from San Francisco to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from San Francisco to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Francisco to Guayaquil (SFO to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Francisco to Guayaquil

Best Price Found

$226

Fastest flight time

13h 19m

Direct flights

None
The best one-way flight to Guayaquil from San Francisco in the past 72 hours is $226. The best round-trip flight deal from San Francisco to Guayaquil found on momondo in the last 72 hours is $532.
The fastest flight from San Francisco to Guayaquil takes 13h 19m
There are no direct flights from San Francisco to Guayaquil. There are no popular flight routes from San Francisco to Guayaquil.
Search flight deals

Frequently asked questions about flying from San Francisco to Guayaquil

  • How far is San Francisco to Guayaquil Jose Joaquin de Olmedo by plane?

    The straight-line distance from San Francisco to Guayaquil Jose Joaquin de Olmedo is 3868.8 mi. By plane, this route typically takes 13h 19m.

  • When did momondo last update prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport refresh daily.

  • How many operators does momondo search for flights from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Francisco Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Francisco to Guayaquil?

Best airlines flying from San Francisco to Guayaquil

Compare and see reviews for airlines that fly from San Francisco to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
JetBluePriceFrom $203Free CancellationRating
7.1
3,035 reviews
Search JetBlue flights
Copa AirlinesPriceFrom $289Free CancellationRating
7.6
1,543 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $486Free CancellationRating
7.4
10,214 reviews
Search United Airlines flights
AviancaPriceFrom $550Free CancellationRating
6.5
2,549 reviews
Search Avianca flights
American AirlinesPriceFrom $570Free CancellationRating
7.1
12,076 reviews
Search American Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Francisco to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Francisco to Guayaquil for you.

Can I find flights from San Francisco to Guayaquil with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Guayaquil from San Francisco with this policy.

How can momondo help me find flights from San Francisco to Guayaquil?

Once you have performed a search for San Francisco to Guayaquil flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from San Francisco to Guayaquil right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guayaquil from San Francisco. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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