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Cheap flights from San Diego to Guayaquil from $183

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from San Diego to Guayaquil departing on 3/31. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from San Diego to Guayaquil

Cheap round-trip flights

Enter your travel dates to find the best prices.
JetBlue Logo
9:30 pm - 5:26 am
SAN
-
GYE
28h 56m2 stops
JetBlue Logo
7:20 am - 7:50 pm
GYE
-
SAN
15h 30m1 stop
$458JetBlue
Sat, Jan 31 - Sat, Feb 7
Multiple Airlines Logo
7:51 am - 7:55 am
SAN
-
GYE
21h 04m1 stop
Multiple Airlines Logo
4:05 pm - 7:46 pm
GYE
-
SAN
30h 41m1 stop
$507Multiple Airlines
Fri, Jan 16 - Mon, Jan 19
Multiple Airlines Logo
12:38 pm - 12:21 am
SAN
-
GYE
32h 43m1 stop
Multiple Airlines Logo
1:26 am - 10:53 am
GYE
-
SAN
12h 27m1 stop
$511Multiple Airlines
Sat, Jan 31 - Fri, Feb 6
American Airlines Logo
6:20 am - 11:22 pm
SAN
-
GYE
14h 02m2 stops
American Airlines Logo
3:31 pm - 9:59 am
GYE
-
SAN
21h 28m2 stops
$518American Airlines
Tue, Feb 3 - Tue, Feb 17
American Airlines Logo
10:45 pm - 11:22 pm
SAN
-
GYE
21h 37m2 stops
American Airlines Logo
3:31 pm - 12:16 pm
GYE
-
SAN
23h 45m1 stop
$531American Airlines
Tue, Feb 3 - Tue, Feb 17
American Airlines Logo
1:27 pm - 11:22 pm
SAN
-
GYE
30h 55m1 stop
American Airlines Logo
3:31 pm - 12:16 pm
GYE
-
SAN
23h 45m1 stop
$539American Airlines
Tue, Feb 3 - Tue, Feb 17
Multiple Airlines Logo
7:51 am - 9:15 am
SAN
-
GYE
22h 24m2 stops
Multiple Airlines Logo
6:55 pm - 7:46 pm
GYE
-
SAN
27h 51m2 stops
$544Multiple Airlines
Sat, Jan 31 - Sat, Feb 7
United Airlines Logo
6:15 am - 11:38 pm
SAN
-
GYE
15h 23m2 stops
United Airlines Logo
12:22 pm - 5:53 pm
GYE
-
SAN
31h 31m2 stops
$547United Airlines
Mon, Apr 20 - Wed, Apr 22
JetBlue Logo
10:20 am - 4:00 am
SAN
-
GYE
15h 40m1 stop
JetBlue Logo
6:00 am - 7:44 pm
GYE
-
SAN
15h 44m1 stop
$548JetBlue
Mon, Apr 20 - Wed, Apr 22
United Airlines Logo
5:00 pm - 8:53 pm
SAN
-
GYE
25h 53m2 stops
United Airlines Logo
2:37 pm - 5:53 pm
GYE
-
SAN
29h 16m2 stops
$557United Airlines
Sat, Apr 18 - Tue, Apr 21

American Airlines flights from San Diego to Guayaquil

Our best American Airlines deals on San Diego to Guayaquil flight tickets
American Airlines
Feb 3
SAN6:20 amSan Diego
14h 02m
2 stops
GYE11:22 pmGuayaquil Jose Joaquin de Olmedo
Feb 17
GYE3:31 pmGuayaquil Jose Joaquin de Olmedo
21h 28m
2 stops
SAN9:59 amSan Diego
$518
Find similar
American Airlines
Feb 3
SAN10:45 pmSan Diego
21h 37m
2 stops
GYE11:22 pmGuayaquil Jose Joaquin de Olmedo
Feb 17
GYE3:31 pmGuayaquil Jose Joaquin de Olmedo
23h 45m
1 stop
SAN12:16 pmSan Diego
$531
Find similar
American Airlines
Feb 3
SAN1:27 pmSan Diego
30h 55m
1 stop
GYE11:22 pmGuayaquil Jose Joaquin de Olmedo
Feb 17
GYE3:31 pmGuayaquil Jose Joaquin de Olmedo
23h 45m
1 stop
SAN12:16 pmSan Diego
$539
Find similar

JetBlue flights from San Diego to Guayaquil

Our best JetBlue deals on San Diego to Guayaquil flight tickets
JetBlue
Jan 31
SAN9:30 pmSan Diego
28h 56m
2 stops
GYE5:26 amGuayaquil Jose Joaquin de Olmedo
Feb 7
GYE7:20 amGuayaquil Jose Joaquin de Olmedo
15h 30m
1 stop
SAN7:50 pmSan Diego
$458
Find similar
JetBlue
Apr 20
SAN10:20 amSan Diego
15h 40m
1 stop
GYE4:00 amGuayaquil Jose Joaquin de Olmedo
Apr 22
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
15h 44m
1 stop
SAN7:44 pmSan Diego
$548
Find similar
JetBlue
Apr 20
SAN10:20 amSan Diego
15h 40m
1 stop
GYE4:00 amGuayaquil Jose Joaquin de Olmedo
Apr 22
GYE6:00 amGuayaquil Jose Joaquin de Olmedo
15h 44m
1 stop
SAN7:44 pmSan Diego
$583
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from San Diego to Guayaquil that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from San Diego to Guayaquil that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoGuayaquil

SAN - GYE

SANGYE

San Diego

Sat 1/31

9:30 pm-5:26 am

2 stops28h 56m

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

7:20 am-7:50 pm

1 stop15h 30m

$458

San DiegoGuayaquil

SAN - GYE

SANGYE

San Diego

Fri 1/16

7:51 am-7:55 am

1 stop21h 04m

Guayaquil Jose Joaquin de Olmedo

Mon 1/19

4:05 pm-7:46 pm

1 stop30h 41m

$507

San DiegoGuayaquil

SAN - GYE

SANGYE

San Diego

Sat 1/31

12:38 pm-12:21 am

1 stop32h 43m

Guayaquil Jose Joaquin de Olmedo

Fri 2/6

1:26 am-10:53 am

1 stop12h 27m

$511

San DiegoGuayaquil

SAN - GYE

SANGYE

San Diego

Tue 2/3

6:20 am-11:22 pm

2 stops14h 02m

Guayaquil Jose Joaquin de Olmedo

Tue 2/17

3:31 pm-9:59 am

2 stops21h 28m

$518

San DiegoGuayaquil

SAN - GYE

SANGYE

San Diego

Tue 2/3

10:45 pm-11:22 pm

2 stops21h 37m

Guayaquil Jose Joaquin de Olmedo

Tue 2/17

3:31 pm-12:16 pm

1 stop23h 45m

$531

San DiegoGuayaquil

SAN - GYE

SANGYE

San Diego

Tue 2/3

1:27 pm-11:22 pm

1 stop30h 55m

Guayaquil Jose Joaquin de Olmedo

Tue 2/17

3:31 pm-12:16 pm

1 stop23h 45m

$539

San DiegoGuayaquil

SAN - GYE

SANGYE

San Diego

Sat 1/31

7:51 am-9:15 am

2 stops22h 24m

Guayaquil Jose Joaquin de Olmedo

Sat 2/7

6:55 pm-7:46 pm

2 stops27h 51m

$544

San DiegoGuayaquil

SAN - GYE

SANGYE

San Diego

Mon 4/20

6:15 am-11:38 pm

2 stops15h 23m

Guayaquil Jose Joaquin de Olmedo

Wed 4/22

12:22 pm-5:53 pm

2 stops31h 31m

$547

San DiegoGuayaquil

SAN - GYE

SANGYE

San Diego

Mon 4/20

10:20 am-4:00 am

1 stop15h 40m

Guayaquil Jose Joaquin de Olmedo

Wed 4/22

6:00 am-7:44 pm

1 stop15h 44m

$548

San DiegoGuayaquil

SAN - GYE

SANGYE

San Diego

Sat 4/18

5:00 pm-8:53 pm

2 stops25h 53m

Guayaquil Jose Joaquin de Olmedo

Tue 4/21

2:37 pm-5:53 pm

2 stops29h 16m

$557

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Guayaquil from

How to get the cheapest flight ticket from San Diego to Guayaquil

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Guayaquil?

The cheapest day to depart from San Diego to Guayaquil is on a Monday. Travelers who choose to depart for Guayaquil on a Monday will often find tickets for as low as $538. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Guayaquil on Friday is $1,012.

What is the cheapest time of day to depart on your flight to Guayaquil?

The cheapest time of day to fly to Guayaquil is in the morning when flights can be purchased for as low as $664. Flights to Guayaquil are more costly in the evening, with an average ticket price of $689. Departure times in the evening fall within the peak daily travel times, which is why tickets can be more expensive.

Can stopping save me money on San Diego to Guayaquil flights?

You could potentially save up to 11% on your flight if you consider stops on a San Diego to Guayaquil flight.

How have San Diego to Guayaquil flight prices changed over time?

When to book flights from San Diego to Guayaquil

Are you open to changing your travel dates? Check out the ideal times to fly from San Diego to Guayaquil according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap San Diego to Guayaquil (SAN to GYE) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from San Diego to Guayaquil

Fastest flight time

12h 42m

Direct flights

None
The fastest flight from San Diego to Guayaquil takes 12h 42m
There are no direct flights from San Diego to Guayaquil. There are no popular flight routes from San Diego to Guayaquil.
Search flight deals

  • How far is San Diego to Guayaquil Jose Joaquin de Olmedo by plane?

    There are 3423.3 mi between San Diego and Guayaquil Jose Joaquin de Olmedo. 13h 48m is a normal flight duration for this route.

  • When did momondo last update prices for flights from San Diego Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    Prices for flights from San Diego Airport to Guayaquil Jose Joaquin de Olmedo Airport are updated daily.

  • How many operators does momondo search for flights from San Diego Airport to Guayaquil Jose Joaquin de Olmedo Airport?

  • How old do you have to be to fly from San Diego Airport to Guayaquil Jose Joaquin de Olmedo Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from San Diego Airport to Guayaquil Jose Joaquin de Olmedo Airport.

  • What documentation or ID do you need to fly to Guayaquil Jose Joaquin de Olmedo Airport?

    The required travel and health documents for your Guayaquil Jose Joaquin de Olmedo Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Guayaquil Jose Joaquin de Olmedo Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from San Diego to Guayaquil?

Best airlines flying from San Diego to Guayaquil

Compare and see reviews for airlines that fly from San Diego to Guayaquil with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $546Free CancellationRating
7.4
9,066 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from San Diego to Guayaquil?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from San Diego to Guayaquil for you.

Can I find flights from San Diego to Guayaquil with flexible booking policies on momondo?

momondo does allow users to show only those flights to Guayaquil from San Diego which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from San Diego to Guayaquil?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Guayaquil from San Diego.

I’m not ready to book a flight from San Diego to Guayaquil right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Guayaquil from San Diego. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

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