Cheap flights from Rome to Chicago from $368

The month of April is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Rome averaging around $763.

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Thursday when prices can be found for as low as $746. This is often the case because there is less demand to fly during this day of the week. On the other hand, Tuesday is the most expensive day to depart from Rome because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $990.

Fly from Rome Fiumicino to Chicago O'Hare Intl for the best Rome - Chicago O'Hare Intl flight prices

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Rome when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $820 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Rome for as low as $648 on momondo.

There are 3 cabin classes available to choose from on Rome to Chicago O'Hare Intl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 3% on your flight if you consider stops on a Rome to Chicago O'Hare Intl Airport flight.

British Airways, Iberia, and Finnair are the most popular carriers operating from Rome to Chicago O'Hare Intl

United Airlines, American Airlines and ITA Airways are the top three most popular airlines that fly to Chicago O'Hare Intl Airport from Rome according to our data. United Airlines is the first choice among our users, with 63% of people opting to fly with this airline when traveling to Chicago O'Hare Intl Airport. Keep in mind that there are 3 different airlines that fly to Chicago O'Hare Intl Airport on a routine basis, so you have a few additional options to choose from.

Historically, on average around 16% of flights between Rome and Chicago have experienced a delay on any given week. The average delay length over the past 12 months has been 171 minutes.

Generally, flights departing in the evening tend to experience fewer delays. Flights at night have, in the past, seen delays more frequently in comparison.

Thursday is statistically the day of the week which experiences the fewest number of delays on this flight route. Sunday has historically seen more delays on average compared to the rest of the week.

According to our data, American Airlines have had the least number of delays on this route over the last 12 months; with about 14% of their flights experiencing any sort of delay.

Dublin (DUB) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Reykjavik (KEF) offer the lowest average round-trip price of $676.

Flights connecting via Dublin (DUB) have the shortest average one-way travel time: 13h 30m.

Dublin (DUB) has the shortest average layover time for this route: 1h 30m.

6 flights are operational daily from Rome to Chicago O'Hare Intl Airport as of November 2026. The most popular departure time for this route is 9:00AM, with 91% of flights per day taking off at noon.

As of November 2026, there are 46 flights per week flying from Rome to Chicago O'Hare Intl Airport. The most common day of the week flights depart is Mon, with 15% of flights taking off on this day.