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Cheap flights from Roanoke to Panama City from $271

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Roanoke to Panama City departing on 4/13. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Roanoke to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
7:59 pm - 4:12 pm
ROA
-
PTY
21h 13m
2 stops
United Airlines Logo
7:55 am - 9:46 am
PTY
-
ROA
24h 51m
2 stops
$581United Airlines
Thu, May 14 - Thu, May 21
United Airlines Logo
8:37 am - 7:31 pm
ROA
-
PTY
11h 54m
2 stops
United Airlines Logo
3:30 pm - 9:44 am
PTY
-
ROA
17h 14m
2 stops
$591United Airlines
Mon, Apr 13 - Tue, Apr 28
Delta Logo
6:00 am - 1:02 pm
ROA
-
PTY
8h 02m
1 stop
Delta Logo
2:27 pm - 12:25 am
PTY
-
ROA
8h 58m
1 stop
$617Delta
Mon, Apr 13 - Tue, Apr 28
United Airlines Logo
7:59 pm - 2:14 pm
ROA
-
PTY
19h 15m
2 stops
United Airlines Logo
10:55 pm - 9:07 pm
PTY
-
ROA
21h 12m
2 stops
$621United Airlines
Mon, Apr 13 - Sat, Apr 25
United Airlines Logo
7:59 pm - 2:14 pm
ROA
-
PTY
19h 15m
2 stops
United Airlines Logo
10:55 pm - 9:07 pm
PTY
-
ROA
21h 12m
2 stops
$632United Airlines
Mon, Apr 13 - Sat, Apr 25
United Airlines Logo
7:59 pm - 4:12 pm
ROA
-
PTY
21h 13m
2 stops
United Airlines Logo
3:30 pm - 9:44 am
PTY
-
ROA
17h 14m
2 stops
$653United Airlines
Mon, Apr 13 - Sat, Apr 25
Delta Logo
6:00 am - 1:02 pm
ROA
-
PTY
8h 02m
1 stop
Delta Logo
2:27 pm - 12:25 am
PTY
-
ROA
8h 58m
1 stop
$697Delta
Mon, Apr 13 - Sat, Apr 25
Delta Logo
6:00 am - 1:02 pm
ROA
-
PTY
8h 02m
1 stop
Delta Logo
2:27 pm - 12:25 am
PTY
-
ROA
8h 58m
1 stop
$709Delta
Mon, Apr 13 - Sat, Apr 25
Delta Logo
6:00 am - 1:02 pm
ROA
-
PTY
8h 02m
1 stop
Delta Logo
2:27 pm - 12:25 am
PTY
-
ROA
8h 58m
1 stop
$794Delta
Mon, Apr 13 - Sat, Apr 25
Delta Logo
6:00 am - 1:02 pm
ROA
-
PTY
8h 02m
1 stop
Delta Logo
2:27 pm - 12:25 am
PTY
-
ROA
8h 58m
1 stop
$837Delta
Mon, Apr 13 - Sat, Apr 25

United Airlines flights from Roanoke to Panama City

Our best United Airlines deals on Roanoke to Panama City flight tickets
United Airlines
May 14
ROA7:59 pmRoanoke
21h 13m
2 stops
PTY4:12 pmPanama City Tocumen Intl
May 21
PTY7:55 amPanama City Tocumen Intl
24h 51m
2 stops
ROA9:46 amRoanoke
$581
United Airlines
Apr 13
ROA8:37 amRoanoke
11h 54m
2 stops
PTY7:31 pmPanama City Tocumen Intl
Apr 28
PTY3:30 pmPanama City Tocumen Intl
17h 14m
2 stops
ROA9:44 amRoanoke
$591
United Airlines
Apr 13
ROA7:59 pmRoanoke
19h 15m
2 stops
PTY2:14 pmPanama City Tocumen Intl
Apr 25
PTY10:55 pmPanama City Tocumen Intl
21h 12m
2 stops
ROA9:07 pmRoanoke
$621

Avianca flights from Roanoke to Panama City

Our best Avianca deals on Roanoke to Panama City flight tickets
Avianca
Apr 13
ROA7:59 pmRoanoke
19h 56m
3 stops
PTY2:55 pmPanama City Tocumen Intl
Apr 25
PTY4:25 amPanama City Tocumen Intl
13h 45m
2 stops
ROA7:10 pmRoanoke
$1,218
Avianca
Apr 13
ROA7:59 pmRoanoke
19h 56m
3 stops
PTY2:55 pmPanama City Tocumen Intl
Apr 25
PTY4:25 amPanama City Tocumen Intl
13h 45m
2 stops
ROA7:10 pmRoanoke
$1,308
Avianca
Apr 11
ROA7:59 pmRoanoke
19h 56m
3 stops
PTY2:55 pmPanama City Tocumen Intl
Apr 19
PTY5:55 pmPanama City Tocumen Intl
24h 15m
2 stops
ROA7:10 pmRoanoke
$1,418

momondo Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 2, 2026.
Use the filters below to find and compare flights from Roanoke to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Thu 5/14

7:59 pm-4:12 pm

2 stops21h 13m

Panama City Tocumen Intl

Thu 5/21

7:55 am-9:46 am

2 stops24h 51m

$581

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 4/13

8:37 am-7:31 pm

2 stops11h 54m

Panama City Tocumen Intl

Tue 4/28

3:30 pm-9:44 am

2 stops17h 14m

$591
Quickest round-trip

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 4/13

6:00 am-1:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Tue 4/28

2:27 pm-12:25 am

1 stop8h 58m

$617

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 4/13

7:59 pm-2:14 pm

2 stops19h 15m

Panama City Tocumen Intl

Sat 4/25

10:55 pm-9:07 pm

2 stops21h 12m

$621

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 4/13

7:59 pm-2:14 pm

2 stops19h 15m

Panama City Tocumen Intl

Sat 4/25

10:55 pm-9:07 pm

2 stops21h 12m

$632

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 4/13

7:59 pm-4:12 pm

2 stops21h 13m

Panama City Tocumen Intl

Sat 4/25

3:30 pm-9:44 am

2 stops17h 14m

$653

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 4/13

6:00 am-1:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Sat 4/25

2:27 pm-12:25 am

1 stop8h 58m

$697

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 4/13

6:00 am-1:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Sat 4/25

2:27 pm-12:25 am

1 stop8h 58m

$709

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 4/13

6:00 am-1:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Sat 4/25

2:27 pm-12:25 am

1 stop8h 58m

$794

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 4/13

6:00 am-1:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Sat 4/25

2:27 pm-12:25 am

1 stop8h 58m

$837

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 17 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Roanoke to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Can stopping save me money on Roanoke to Panama City flights?

You could potentially save up to 6% on your flight if you consider stops on a Roanoke to Panama City flight.

When to book flights from Roanoke to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Roanoke to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Roanoke to Panama City (ROA to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Roanoke to Panama City

Fastest flight time

12h 52m

Direct flights

None
The fastest flight from Roanoke to Panama City takes 12h 52m
There are no direct flights from Roanoke to Panama City. There are no popular flight routes from Roanoke to Panama City.
Search flight deals

Frequently asked questions about flying from Roanoke to Panama City

  • How far is Roanoke to Panama City Tocumen Intl by plane?

    Roanoke and Panama City Tocumen Intl are 1953.3 mi apart from one another. Flights usually cover this in 12h 52m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Roanoke Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Roanoke Airport to Panama City Tocumen Intl Airport refresh daily.

  • How old do you have to be to fly from Roanoke Airport to Panama City Tocumen Intl Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Roanoke Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The required travel and health documents for your Panama City Tocumen Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Panama City Tocumen Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Roanoke to Panama City?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Roanoke to Panama City. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Roanoke to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Roanoke which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Roanoke to Panama City?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Roanoke to Panama City.

I’m not ready to book a flight from Roanoke to Panama City right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Roanoke to Panama City flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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