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Cheap flights from Portland to Santa Cruz de la Sierra from $475

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Portland to Santa Cruz de la Sierra departing on 8/18. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Portland to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
11:30 pm - 10:44 pmPDX  Portland-VVI Santa Cruz de la Sierra Viru Viru Intl
20h 14m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
United Airlines Logo
11:55 am - 11:09 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-PDX Portland
38h 14m2 stops Panama City Tocumen Intl Denver Intl
$929United Airlines
Tue, Oct 20 - Thu, Oct 29
United Airlines Logo
11:30 pm - 10:44 pmPDX  Portland-VVI Santa Cruz de la Sierra Viru Viru Intl
20h 14m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
United Airlines Logo
11:55 am - 11:15 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-PDX Portland
38h 20m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$929United Airlines
Wed, Oct 21 - Thu, Oct 29
United Airlines Logo
11:30 pm - 3:38 amPDX  Portland-VVI Santa Cruz de la Sierra Viru Viru Intl
25h 08m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
United Airlines Logo
11:55 am - 9:02 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-PDX Portland
36h 07m3 stops Panama City Tocumen Intl Chicago O'Hare Intl San Francisco
$929United Airlines
Tue, Oct 20 - Tue, Oct 27
United Airlines Logo
11:30 pm - 3:38 amPDX  Portland-VVI Santa Cruz de la Sierra Viru Viru Intl
25h 08m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
United Airlines Logo
11:55 am - 10:46 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-PDX Portland
37h 51m2 stops Panama City Tocumen Intl San Francisco
$929United Airlines
Tue, Oct 20 - Tue, Oct 27
Avianca Logo
10:33 pm - 10:44 pmPDX  Portland-VVI Santa Cruz de la Sierra Viru Viru Intl
45h 11m2 stops Newark Panama City Tocumen Intl
Avianca Logo
3:40 am - 9:58 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-PDX Portland
21h 18m2 stops Bogotá El Dorado Newark
$937Avianca
Wed, Oct 21 - Tue, Oct 27
Multiple Airlines Logo
12:45 pm - 10:44 pmPDX  Portland-VVI Santa Cruz de la Sierra Viru Viru Intl
30h 59m3 stops Denver Intl Chicago O'Hare Intl Panama City Tocumen Intl
Multiple Airlines Logo
3:40 am - 12:13 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-PDX Portland
35h 33m2 stops Bogotá El Dorado Houston George Bush Intcntl
$950Multiple Airlines
Wed, Oct 21 - Tue, Oct 27
United Airlines Logo
7:02 am - 3:38 amPDX  Portland-VVI Santa Cruz de la Sierra Viru Viru Intl
17h 36m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
United Airlines Logo
11:55 am - 10:27 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-PDX Portland
37h 32m3 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl Chicago O'Hare Intl
$952United Airlines
Wed, Oct 21 - Thu, Oct 29
United Airlines Logo
11:30 pm - 10:44 pmPDX  Portland-VVI Santa Cruz de la Sierra Viru Viru Intl
20h 14m2 stops Chicago O'Hare Intl Panama City Tocumen Intl
United Airlines Logo
11:55 am - 10:27 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-PDX Portland
37h 32m3 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl Chicago O'Hare Intl
$952United Airlines
Tue, Oct 20 - Thu, Oct 29
Copa Airlines Logo
10:33 pm - 3:38 amPDX  Portland-VVI Santa Cruz de la Sierra Viru Viru Intl
26h 05m2 stops Newark Panama City Tocumen Intl
Copa Airlines Logo
1:12 am - 11:15 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-PDX Portland
25h 03m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$964Copa Airlines
Tue, Oct 20 - Tue, Oct 27
Copa Airlines Logo
11:59 pm - 3:38 amPDX  Portland-VVI Santa Cruz de la Sierra Viru Viru Intl
24h 39m2 stops Houston George Bush Intcntl Panama City Tocumen Intl
Copa Airlines Logo
1:12 am - 11:15 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-PDX Portland
25h 03m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$997Copa Airlines
Thu, Oct 22 - Tue, Oct 27

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United Airlines flights from Portland to Santa Cruz de la Sierra

Our best United Airlines deals on Portland to Santa Cruz de la Sierra flight tickets
United Airlines
Oct 20
PDX11:30 pmPortland
25h 08m
2 stops
VVI3:38 amSanta Cruz de la Sierra Viru Viru Intl
Oct 27
VVI11:55 amSanta Cruz de la Sierra Viru Viru Intl
37h 51m
2 stops
PDX10:46 pmPortland
$929
United Airlines
Oct 20
PDX11:30 pmPortland
20h 14m
2 stops
VVI10:44 pmSanta Cruz de la Sierra Viru Viru Intl
Oct 29
VVI11:55 amSanta Cruz de la Sierra Viru Viru Intl
37h 32m
3 stops
PDX10:27 pmPortland
$952
United Airlines
Oct 21
PDX7:02 amPortland
17h 36m
2 stops
VVI3:38 amSanta Cruz de la Sierra Viru Viru Intl
Oct 27
VVI11:55 amSanta Cruz de la Sierra Viru Viru Intl
37h 32m
2 stops
PDX10:27 pmPortland
$954

momondo Fare Finder

 
Customize your flight search to find flights from Portland to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 5, 2026.
Use the filters below to find and compare flights from Portland to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

PortlandSanta Cruz de la Sierra

PDX Portland - VVI Santa Cruz de la Sierra Viru Viru Intl

PDXVVI

Portland

Tue 10/20

11:30 pm-10:44 pm

2 stops20h 14m

Santa Cruz de la Sierra Viru Viru Intl

Thu 10/29

11:55 am-11:09 pm

2 stops38h 14m

$929

PortlandSanta Cruz de la Sierra

PDX Portland - VVI Santa Cruz de la Sierra Viru Viru Intl

PDXVVI

Portland

Wed 10/21

11:30 pm-10:44 pm

2 stops20h 14m

Santa Cruz de la Sierra Viru Viru Intl

Thu 10/29

11:55 am-11:15 pm

2 stops38h 20m

$929

PortlandSanta Cruz de la Sierra

PDX Portland - VVI Santa Cruz de la Sierra Viru Viru Intl

PDXVVI

Portland

Tue 10/20

11:30 pm-3:38 am

2 stops25h 08m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/27

11:55 am-9:02 pm

3 stops36h 07m

$929

PortlandSanta Cruz de la Sierra

PDX Portland - VVI Santa Cruz de la Sierra Viru Viru Intl

PDXVVI

Portland

Tue 10/20

11:30 pm-3:38 am

2 stops25h 08m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/27

11:55 am-10:46 pm

2 stops37h 51m

$929

PortlandSanta Cruz de la Sierra

PDX Portland - VVI Santa Cruz de la Sierra Viru Viru Intl

PDXVVI

Portland

Wed 10/21

10:33 pm-10:44 pm

2 stops45h 11m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/27

3:40 am-9:58 pm

2 stops21h 18m

$937

PortlandSanta Cruz de la Sierra

PDX Portland - VVI Santa Cruz de la Sierra Viru Viru Intl

PDXVVI

Portland

Wed 10/21

12:45 pm-10:44 pm

3 stops30h 59m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/27

3:40 am-12:13 pm

2 stops35h 33m

$950

PortlandSanta Cruz de la Sierra

PDX Portland - VVI Santa Cruz de la Sierra Viru Viru Intl

PDXVVI

Portland

Wed 10/21

7:02 am-3:38 am

2 stops17h 36m

Santa Cruz de la Sierra Viru Viru Intl

Thu 10/29

11:55 am-10:27 pm

3 stops37h 32m

$952

PortlandSanta Cruz de la Sierra

PDX Portland - VVI Santa Cruz de la Sierra Viru Viru Intl

PDXVVI

Portland

Tue 10/20

11:30 pm-10:44 pm

2 stops20h 14m

Santa Cruz de la Sierra Viru Viru Intl

Thu 10/29

11:55 am-10:27 pm

3 stops37h 32m

$952

PortlandSanta Cruz de la Sierra

PDX Portland - VVI Santa Cruz de la Sierra Viru Viru Intl

PDXVVI

Portland

Tue 10/20

10:33 pm-3:38 am

2 stops26h 05m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/27

1:12 am-11:15 pm

2 stops25h 03m

$964
Quickest round-trip

PortlandSanta Cruz de la Sierra

PDX Portland - VVI Santa Cruz de la Sierra Viru Viru Intl

PDXVVI

Portland

Thu 10/22

11:59 pm-3:38 am

2 stops24h 39m

Santa Cruz de la Sierra Viru Viru Intl

Tue 10/27

1:12 am-11:15 pm

2 stops25h 03m

$997

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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When to book flights from Portland to Santa Cruz de la Sierra

Are you open to changing your travel dates? Check out the ideal times to fly from Portland to Santa Cruz de la Sierra according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Portland to Santa Cruz de la Sierra (PDX to VVI) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Portland to Santa Cruz de la Sierra

Fastest flight time

28h 16m

Direct flights

None
The fastest flight from Portland to Santa Cruz de la Sierra takes 28h 16m
There are no direct flights from Portland to Santa Cruz de la Sierra. There are no popular flight routes from Portland to Santa Cruz de la Sierra.
Search flight deals

Frequently asked questions about flying from Portland to Santa Cruz de la Sierra

  • How far is Portland to Santa Cruz de la Sierra Viru Viru Intl by plane?

    The distance between Portland and Santa Cruz de la Sierra Viru Viru Intl is about 5737.8 mi. By plane, this route typically takes 28h 16m.

  • When did momondo last update prices for flights from Portland Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Portland Airport to Santa Cruz de la Sierra Viru Viru Intl Airport are updated daily.

  • How many operators does momondo search for flights from Portland Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from Portland Airport to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Portland Airport to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The travel and health documents required for your trip to Santa Cruz de la Sierra Viru Viru Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santa Cruz de la Sierra Viru Viru Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Portland to Santa Cruz de la Sierra?

Best airlines flying from Portland to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from Portland to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $997Free CancellationRating
7.6
1,565 reviews
Search Copa Airlines flights

Frequently asked questions about flying from Portland to Santa Cruz de la Sierra

  • How do I get Price Alerts for flights from Portland to Santa Cruz de la Sierra?

    Confirm your travel details to search for the latest offers for flights from Portland to Santa Cruz de la Sierra. While browsing offers there will be the option to toggle “Price Alerts”. You’ll then receive updates when prices for the flight route increase or decrease.

  • How can I save money on flights from Portland to Santa Cruz de la Sierra with momondo?

    Plan your trips smart with the “Price Forecast” feature, which uses flight data to help you pick the best days to fly for the lowest fares. Our “Price Calendar” helps you get the most for your money by showing you when it’s most advantageous to fly. Curate your own travel experiences for less with “Explore”. Expert travel hacks to fuel your next adventure are a click away with “Discover” by momondo. Set up our “Price Alerts” to track fare changes and book when prices are at their lowest point.

  • How does momondo find its flight prices?

    We aggregate our prices from over 700+ competitors from airlines to OTAs. We operate in over 30 markets worldwide to show you a wide range of travel options.

Why use momondo?

Why should I use momondo to find a flight deal from Portland to Santa Cruz de la Sierra?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Portland to Santa Cruz de la Sierra. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Portland to Santa Cruz de la Sierra with flexible booking policies on momondo?

Flights from Portland to Santa Cruz de la Sierra with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Portland to Santa Cruz de la Sierra?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santa Cruz de la Sierra from Portland.

I’m not ready to book a flight from Portland to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Portland to Santa Cruz de la Sierra flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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