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Cheap flights from Panama to Chicago from $240

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama to Chicago departing on 10/29. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama to Chicago

Recent round-trip flight deals from Panama to Chicago

Logo
5:25 pm - 9:18 amPTY-ORD
15h 53m2 stops
Logo
10:27 am - 12:45 amORD-PTY
14h 18m2 stops
$406
Find Deal
Wed, Sep 17 - Fri, Sep 26
Logo
1:30 pm - 9:18 amPTY-ORD
19h 48m3 stops
Logo
10:27 am - 8:55 amORD-PTY
22h 28m2 stops
$414
Find Deal
Wed, Sep 17 - Fri, Sep 26
Avianca Logo
2:55 am - 9:20 pmPTY-ORD
18h 25m1 stop
Avianca Logo
10:20 pm - 8:50 amORD-PTY
9h 30m1 stop
$485Avianca
Find Deal
Fri, Oct 31 - Thu, Nov 6
Copa Airlines Logo
6:45 pm - 12:21 amPTY-ORD
5h 36mnonstop
Copa Airlines Logo
8:02 am - 1:22 pmORD-PTY
5h 20mnonstop
$495Copa Airlines
Find Deal
Mon, Sep 8 - Thu, Sep 18
United Airlines Logo
3:30 pm - 9:24 amPTY-ORD
17h 54m1 stop
United Airlines Logo
7:00 am - 6:37 pmORD-PTY
11h 37m1 stop
$500United Airlines
Find Deal
Sat, Sep 6 - Fri, Sep 12
Avianca Logo
3:20 am - 1:15 pmPTY-ORD
9h 55m1 stop
Avianca Logo
2:35 pm - 12:45 amORD-PTY
10h 10m1 stop
$505Avianca
Find Deal
Thu, Sep 18 - Mon, Sep 22
United Airlines Logo
3:30 pm - 9:21 amPTY-ORD
17h 51m1 stop
United Airlines Logo
7:55 pm - 1:45 pmORD-PTY
17h 50m1 stop
$509United Airlines
Find Deal
Mon, Oct 13 - Sat, Oct 25
Copa Airlines Logo
7:55 am - 1:41 pmPTY-ORD
5h 46mnonstop
Copa Airlines Logo
8:02 am - 1:22 pmORD-PTY
5h 20mnonstop
$511Copa Airlines
Find Deal
Wed, Sep 10 - Sat, Sep 20
American Airlines Logo
3:31 pm - 7:42 amPTY-ORD
16h 11m2 stops
American Airlines Logo
5:05 pm - 2:03 pmORD-PTY
20h 58m1 stop
$512American Airlines
Find Deal
Sat, Oct 4 - Sat, Oct 11
American Airlines Logo
3:15 pm - 7:25 amPTY-ORD
16h 10m2 stops
American Airlines Logo
8:44 pm - 2:03 pmORD-PTY
17h 19m2 stops
$514American Airlines
Find Deal
Tue, Oct 14 - Fri, Oct 24

United Airlines flights from Panama to Chicago O'Hare Intl Airport

Our best United Airlines deals on Panama to Chicago O'Hare Intl Airport flight tickets
United Airlines
Aug 30
PTY3:30 pmPanama City Tocumen Intl
17h 54m
1 stop
ORD9:24 amChicago O'Hare Intl
Sep 15
ORD9:05 pmChicago O'Hare Intl
17h 09m
1 stop
PTY2:14 pmPanama City Tocumen Intl
$500
Find similar
United Airlines
Oct 13
PTY3:30 pmPanama City Tocumen Intl
17h 51m
1 stop
ORD9:21 amChicago O'Hare Intl
Oct 25
ORD7:55 pmChicago O'Hare Intl
17h 50m
1 stop
PTY1:45 pmPanama City Tocumen Intl
$509
Find similar
United Airlines
Sep 13
PTY3:30 pmPanama City Tocumen Intl
17h 54m
1 stop
ORD9:24 amChicago O'Hare Intl
Sep 20
ORD3:58 pmChicago O'Hare Intl
22h 16m
1 stop
PTY2:14 pmPanama City Tocumen Intl
$529
Find similar

Copa Airlines flights from Panama to Chicago O'Hare Intl Airport

Our best Copa Airlines deals on Panama to Chicago O'Hare Intl Airport flight tickets
Copa Airlines
Aug 30
PTY6:45 pmPanama City Tocumen Intl
5h 36m
ORD12:21 amChicago O'Hare Intl
Sep 15
ORD3:07 pmChicago O'Hare Intl
5h 28m
PTY8:35 pmPanama City Tocumen Intl
$495
Find similar
Copa Airlines
Sep 10
PTY7:55 amPanama City Tocumen Intl
5h 46m
ORD1:41 pmChicago O'Hare Intl
Sep 20
ORD8:02 amChicago O'Hare Intl
5h 20m
PTY1:22 pmPanama City Tocumen Intl
$511
Find similar
Copa Airlines
Aug 26
PTY6:45 pmPanama City Tocumen Intl
5h 36m
ORD12:21 amChicago O'Hare Intl
Aug 28
ORD7:55 amChicago O'Hare Intl
5h 27m
PTY1:22 pmPanama City Tocumen Intl
$617
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama to Chicago O'Hare Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 21, 2025.
Use the filters below to find and compare flights from Panama to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 9/17

5:25 pm-9:18 am

2 stops15h 53m

Chicago O'Hare Intl

Fri 9/26

10:27 am-12:45 am

2 stops14h 18m

$406

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 9/17

1:30 pm-9:18 am

3 stops19h 48m

Chicago O'Hare Intl

Fri 9/26

10:27 am-8:55 am

2 stops22h 28m

$414

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 10/31

2:55 am-9:20 pm

1 stop18h 25m

Chicago O'Hare Intl

Thu 11/6

10:20 pm-8:50 am

1 stop9h 30m

$485

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 9/8

6:45 pm-12:21 am

Nonstop5h 36m

Chicago O'Hare Intl

Thu 9/18

8:02 am-1:22 pm

Nonstop5h 20m

$495

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 9/6

3:30 pm-9:24 am

1 stop17h 54m

Chicago O'Hare Intl

Fri 9/12

7:00 am-6:37 pm

1 stop11h 37m

$500

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 9/18

3:20 am-1:15 pm

1 stop9h 55m

Chicago O'Hare Intl

Mon 9/22

2:35 pm-12:45 am

1 stop10h 10m

$505

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 10/13

3:30 pm-9:21 am

1 stop17h 51m

Chicago O'Hare Intl

Sat 10/25

7:55 pm-1:45 pm

1 stop17h 50m

$509

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 9/10

7:55 am-1:41 pm

Nonstop5h 46m

Chicago O'Hare Intl

Sat 9/20

8:02 am-1:22 pm

Nonstop5h 20m

$511

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 10/4

3:31 pm-7:42 am

2 stops16h 11m

Chicago O'Hare Intl

Sat 10/11

5:05 pm-2:03 pm

1 stop20h 58m

$512

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 10/14

3:15 pm-7:25 am

2 stops16h 10m

Chicago O'Hare Intl

Fri 10/24

8:44 pm-2:03 pm

2 stops17h 19m

$514

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Panama to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of March is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Panama averaging around $489.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Wednesday when prices can be found for as low as $529. This is often the case because there is less demand to fly during this day of the week. On the other hand, Tuesday is the most expensive day to depart from Panama because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,166.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Panama in the afternoon is the least expensive time of day to depart. momondo users have found prices as low as $552 when looking at flights departing in the afternoon. Try not to purchase tickets in the morning because they tend to be around $679. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Panama to Chicago O'Hare Intl flight route?

Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Panama when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $559 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Panama for as low as $478 on momondo.

What cabin class options are available on Panama to Chicago O'Hare Intl flights?

There are 3 cabin classes available to choose from on Panama to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Panama to Chicago O'Hare Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Chicago O'Hare Intl Airport

Best Price Found

$263

Fastest flight time

5h 36m

Direct flights

Every day
The best one-way flight to Chicago O'Hare Intl Airport from Panama in the past 72 hours is $263. The best round-trip flight deal from Panama to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $465.
The fastest flight from Panama to Chicago O'Hare Intl Airport takes 5h 36m
Direct flights go from Panama to Chicago O'Hare Intl Airport every day.
Search flight deals

  • When did momondo last update prices for flights from Panama to Chicago O'Hare Intl Airport?

    Prices for flights from Panama to Chicago O'Hare Intl Airport are updated daily.

  • How many operators does momondo search for flights from Panama to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Panama to Chicago O'Hare Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The required travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago O'Hare Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Panama to Chicago O'Hare Intl Airport?

Best airlines flying from Panama to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Panama to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $415Free CancellationRating
7.5
1,512 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $485Free CancellationRating
7.4
8,930 reviews
Search United Airlines flights
DeltaPriceFrom $569Free CancellationRating
7.9
7,981 reviews
Search Delta flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
Rockford
South Haven
Schaumburg
Merrillville
Gurnee
Naperville
Rosemont
Kenosha
New Buffalo
Joliet
Oak Brook
Racine
Hammond
Tinley Park
Orland Park
Elgin
Aurora
Janesville
Benton Harbor

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Chicago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama to Chicago. momondo saves you time and could save you money on your trip.

Can I find flights from Panama to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Panama which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from Panama. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama to Chicago right now. Can momondo alert me if prices change?

Price alerts on flights to Chicago from Panama are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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