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Cheap flights from Panama to Chicago from $378

1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Panama to Chicago

Recent round-trip flight deals from Panama to Chicago

Enter your travel dates to find the best prices.
American Airlines Logo
2:26 pm - 1:05 amPTY  Panama City Tocumen Intl-ORD Chicago O'Hare Intl
11h 39m1 stop Miami
American Airlines Logo
5:59 pm - 1:26 pmORD  Chicago O'Hare Intl-PTY Panama City Tocumen Intl
18h 27m1 stop Miami
$689American Airlines
Wed, Jan 27 - Thu, Feb 4
American Airlines Logo
2:26 pm - 7:27 amPTY  Panama City Tocumen Intl-ORD Chicago O'Hare Intl
18h 01m2 stops Miami Washington, D.C. Reagan-National
American Airlines Logo
5:59 pm - 1:26 pmORD  Chicago O'Hare Intl-PTY Panama City Tocumen Intl
18h 27m1 stop Miami
$693American Airlines
Wed, Jan 27 - Thu, Feb 4
American Airlines Logo
2:26 pm - 7:27 amPTY  Panama City Tocumen Intl-ORD Chicago O'Hare Intl
18h 01m2 stops Miami Washington, D.C. Reagan-National
American Airlines Logo
8:55 pm - 1:26 pmORD  Chicago O'Hare Intl-PTY Panama City Tocumen Intl
15h 31m2 stops Charlotte Douglas Miami
$693American Airlines
Wed, Jan 27 - Thu, Feb 4
American Airlines Logo
2:41 pm - 12:33 amPTY  Panama City Tocumen Intl-ORD Chicago O'Hare Intl
10h 52m1 stop Miami
American Airlines Logo
5:59 pm - 1:26 pmORD  Chicago O'Hare Intl-PTY Panama City Tocumen Intl
18h 27m1 stop Miami
$707American Airlines
Wed, Dec 23 - Mon, Jan 11
American Airlines Logo
4:33 pm - 8:20 amPTY  Panama City Tocumen Intl-ORD Chicago O'Hare Intl
16h 47m2 stops Miami Washington, D.C. Reagan-National
American Airlines Logo
8:59 pm - 1:26 pmORD  Chicago O'Hare Intl-PTY Panama City Tocumen Intl
15h 27m2 stops Washington, D.C. Reagan-National Miami
$711American Airlines
Wed, Dec 23 - Mon, Jan 11
American Airlines Logo
4:33 pm - 9:23 amPTY  Panama City Tocumen Intl-ORD Chicago O'Hare Intl
17h 50m1 stop Miami
American Airlines Logo
8:59 pm - 1:26 pmORD  Chicago O'Hare Intl-PTY Panama City Tocumen Intl
15h 27m2 stops Washington, D.C. Reagan-National Miami
$711American Airlines
Wed, Dec 23 - Mon, Jan 11
American Airlines Logo
4:24 pm - 12:47 amPTY  Panama City Tocumen Intl-ORD Chicago O'Hare Intl
9h 23m1 stop Miami
American Airlines Logo
6:00 am - 2:24 pmORD  Chicago O'Hare Intl-PTY Panama City Tocumen Intl
8h 24m1 stop Miami
$715American Airlines
Wed, Mar 10 - Tue, Mar 16
Multiple Airlines Logo
4:10 pm - 10:13 pmPTY  Panama City Tocumen Intl-ORD Chicago O'Hare Intl
31h 03m3 stops Bogotá El Dorado Guatemala City La Aurora Mexico City Benito Juarez
Multiple Airlines Logo
12:04 am - 2:10 amORD  Chicago O'Hare Intl-PTY Panama City Tocumen Intl
25h 06m3 stops Mexico City Benito Juarez Guatemala City La Aurora San Salvador El Salvador Intl
$736Multiple Airlines
Sat, Feb 6 - Tue, Feb 9
Copa Airlines Logo
7:28 pm - 12:11 amPTY  Panama City Tocumen Intl-ORD Chicago O'Hare Intl
5h 43mnonstop
Copa Airlines Logo
2:13 pm - 8:37 pmORD  Chicago O'Hare Intl-PTY Panama City Tocumen Intl
5h 24mnonstop
$757Copa Airlines
Thu, Nov 19 - Mon, Nov 23
Copa Airlines Logo
8:05 am - 12:46 pmPTY  Panama City Tocumen Intl-ORD Chicago O'Hare Intl
5h 41mnonstop
Copa Airlines Logo
2:17 pm - 8:41 pmORD  Chicago O'Hare Intl-PTY Panama City Tocumen Intl
5h 24mnonstop
$757Copa Airlines
Mon, Nov 23 - Thu, Dec 10

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American Airlines flights from Panama to Chicago O'Hare Intl Airport

Our best American Airlines deals on Panama to Chicago O'Hare Intl Airport flight tickets
American Airlines
Jan 27
PTY2:26 pmPanama City Tocumen Intl
11h 39m
1 stop
ORD1:05 amChicago O'Hare Intl
Feb 4
ORD5:59 pmChicago O'Hare Intl
18h 27m
1 stop
PTY1:26 pmPanama City Tocumen Intl
$689
American Airlines
Jan 27
PTY2:26 pmPanama City Tocumen Intl
18h 01m
2 stops
ORD7:27 amChicago O'Hare Intl
Feb 4
ORD8:55 pmChicago O'Hare Intl
15h 31m
2 stops
PTY1:26 pmPanama City Tocumen Intl
$693
American Airlines
Dec 23
PTY2:41 pmPanama City Tocumen Intl
10h 52m
1 stop
ORD12:33 amChicago O'Hare Intl
Jan 11
ORD5:59 pmChicago O'Hare Intl
18h 27m
1 stop
PTY1:26 pmPanama City Tocumen Intl
$707

Avianca flights from Panama to Chicago O'Hare Intl Airport

Our best Avianca deals on Panama to Chicago O'Hare Intl Airport flight tickets
Avianca
Nov 19
PTY10:05 amPanama City Tocumen Intl
11h 25m
1 stop
ORD8:30 pmChicago O'Hare Intl
Nov 23
ORD10:30 pmChicago O'Hare Intl
15h 45m
1 stop
PTY3:15 pmPanama City Tocumen Intl
$822
Avianca
Nov 3
PTY2:30 amPanama City Tocumen Intl
19h 00m
1 stop
ORD8:30 pmChicago O'Hare Intl
Nov 10
ORD10:30 pmChicago O'Hare Intl
9h 40m
1 stop
PTY9:10 amPanama City Tocumen Intl
$872
Avianca
Nov 5
PTY5:30 amPanama City Tocumen Intl
16h 00m
2 stops
ORD8:30 pmChicago O'Hare Intl
Nov 10
ORD10:30 pmChicago O'Hare Intl
26h 40m
2 stops
PTY2:10 amPanama City Tocumen Intl
$1,073

momondo Fare Finder

 
Use the filters below to find and compare flights from Panama to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityChicago

PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl

PTYORD

Panama City Tocumen Intl

Wed 1/27

2:26 pm-1:05 am

1 stop11h 39m

Chicago O'Hare Intl

Thu 2/4

5:59 pm-1:26 pm

1 stop18h 27m

$689

Panama CityChicago

PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl

PTYORD

Panama City Tocumen Intl

Wed 1/27

2:26 pm-7:27 am

2 stops18h 01m

Chicago O'Hare Intl

Thu 2/4

5:59 pm-1:26 pm

1 stop18h 27m

$693

Panama CityChicago

PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl

PTYORD

Panama City Tocumen Intl

Wed 1/27

2:26 pm-7:27 am

2 stops18h 01m

Chicago O'Hare Intl

Thu 2/4

8:55 pm-1:26 pm

2 stops15h 31m

$693

Panama CityChicago

PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl

PTYORD

Panama City Tocumen Intl

Wed 12/23

2:41 pm-12:33 am

1 stop10h 52m

Chicago O'Hare Intl

Mon 1/11

5:59 pm-1:26 pm

1 stop18h 27m

$707

Panama CityChicago

PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl

PTYORD

Panama City Tocumen Intl

Wed 12/23

4:33 pm-8:20 am

2 stops16h 47m

Chicago O'Hare Intl

Mon 1/11

8:59 pm-1:26 pm

2 stops15h 27m

$711

Panama CityChicago

PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl

PTYORD

Panama City Tocumen Intl

Wed 12/23

4:33 pm-9:23 am

1 stop17h 50m

Chicago O'Hare Intl

Mon 1/11

8:59 pm-1:26 pm

2 stops15h 27m

$711

Panama CityChicago

PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl

PTYORD

Panama City Tocumen Intl

Wed 3/10

4:24 pm-12:47 am

1 stop9h 23m

Chicago O'Hare Intl

Tue 3/16

6:00 am-2:24 pm

1 stop8h 24m

$715

Panama CityChicago

PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl

PTYORD

Panama City Tocumen Intl

Sat 2/6

4:10 pm-10:13 pm

3 stops31h 03m

Chicago O'Hare Intl

Tue 2/9

12:04 am-2:10 am

3 stops25h 06m

$736

Panama CityChicago

PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl

PTYORD

Panama City Tocumen Intl

Thu 11/19

7:28 pm-12:11 am

Nonstop5h 43m

Chicago O'Hare Intl

Mon 11/23

2:13 pm-8:37 pm

Nonstop5h 24m

$757
Quickest round-trip

Panama CityChicago

PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl

PTYORD

Panama City Tocumen Intl

Mon 11/23

8:05 am-12:46 pm

Nonstop5h 41m

Chicago O'Hare Intl

Thu 12/10

2:17 pm-8:41 pm

Nonstop5h 24m

$757

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Chicago from

How to get the cheapest flight ticket from Panama to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of January is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Panama averaging around $596.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Wednesday when prices can be found for as low as $779. This is often the case because there is less demand to fly during this day of the week. On the other hand, Sunday is the most expensive day to depart from Panama because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,152.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Panama in the morning is the least expensive time of day to depart. momondo users have found prices as low as $885 when looking at flights departing in the morning. Try not to purchase tickets in the evening because they tend to be around $887. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Panama to Chicago O'Hare Intl flight route?

Fly from Panama City Tocumen Intl to Chicago O'Hare Intl for the best Panama - Chicago O'Hare Intl flight prices

What cabin class options are available on Panama to Chicago O'Hare Intl Airport flights?

There are 3 cabin classes available to choose from on Panama to Chicago O'Hare Intl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama to Chicago O'Hare Intl Airport flights?

No. A direct flight is the cheapest option for a flight between Panama to Chicago O'Hare Intl Airport.

Cheap Panama to Chicago O'Hare Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama to Chicago O'Hare Intl Airport

Best Price Found

$378

Fastest flight time

5h 36m

Direct flights

Every day
The best one-way flight to Chicago O'Hare Intl Airport from Panama in the past 72 hours is $378. The best round-trip flight deal from Panama to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $689.
The fastest flight from Panama to Chicago O'Hare Intl Airport takes 5h 36m
Direct flights go from Panama to Chicago O'Hare Intl Airport every day.
Search flight deals

Frequently asked questions about flying from Panama to Chicago O'Hare Intl Airport

  • When did momondo last update prices for flights from Panama to Chicago O'Hare Intl Airport?

    Prices for flights from Panama to Chicago O'Hare Intl Airport are updated daily.

  • How many operators does momondo search for flights from Panama to Chicago O'Hare Intl Airport?

  • How old do you have to be to fly from Panama to Chicago O'Hare Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama to Chicago O'Hare Intl Airport.

  • What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

    The required travel and health documents for your Chicago O'Hare Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Chicago O'Hare Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Panama to Chicago O'Hare Intl Airport?

Best airlines flying from Panama to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Panama to Chicago O'Hare Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $574Free CancellationRating
7.6
1,552 reviews
Search Copa Airlines flights

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lake Geneva
Schaumburg
Merrillville
Rockford
South Haven
Oak Brook
Rosemont
Gurnee
Orland Park
Joliet
Naperville
New Buffalo
Kenosha
Hammond
Aurora
Racine
Elgin
Janesville
Skokie
Waukegan

Why use momondo?

Why should I use momondo to find a flight deal from Panama to Chicago?

momondo collates all your flight options in one place and lets you filter them to find the perfect flight from Panama to Chicago. momondo saves you time and could save you money on your trip.

Can I find flights from Panama to Chicago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Chicago from Panama which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Panama to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from Panama. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Panama to Chicago right now. Can momondo alert me if prices change?

Price alerts on flights to Chicago from Panama are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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