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Cheap flights from Panama City to Sao Paulo from $282

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Sao Paulo departing on 12/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
3:20 am - 3:20 pm
PTY
-
GRU
10h 00m1 stop
Avianca Logo
7:20 am - 4:30 pm
GRU
-
PTY
11h 10m1 stop
$500Avianca
Sun, May 10 - Wed, May 13
Avianca Logo
9:45 am - 10:40 pm
PTY
-
GRU
10h 55m1 stop
Avianca Logo
7:35 am - 4:55 pm
GRU
-
PTY
11h 20m1 stop
$519Avianca
Wed, Jan 21 - Tue, Mar 10
Avianca Logo
9:55 am - 2:10 am
PTY
-
GRU
14h 15m1 stop
Avianca Logo
4:50 pm - 12:45 am
GRU
-
PTY
9h 55m1 stop
$522Avianca
Thu, May 21 - Mon, May 25
Multiple Airlines Logo
3:20 am - 3:20 pm
PTY
-
GRU
10h 00m1 stop
Multiple Airlines Logo
4:50 pm - 12:10 am
GRU
-
PTY
9h 20m1 stop
$528Multiple Airlines
Tue, Apr 14 - Sat, Apr 18
Copa Airlines Logo
9:46 pm - 6:30 am
PTY
-
GRU
6h 44mnonstop
Copa Airlines Logo
3:10 am - 7:59 am
GRU
-
PTY
6h 49mnonstop
$529Copa Airlines
Thu, Mar 19 - Wed, Mar 25
Copa Airlines Logo
3:20 pm - 12:10 am
PTY
-
GRU
6h 50mnonstop
Copa Airlines Logo
5:25 am - 10:23 am
GRU
-
PTY
6h 58mnonstop
$538Copa Airlines
Thu, May 21 - Mon, May 25
Avianca Logo
9:45 am - 1:35 am
PTY
-
GRU
13h 50m1 stop
Avianca Logo
1:20 am - 4:55 pm
GRU
-
PTY
17h 35m1 stop
$541Avianca
Thu, Mar 19 - Wed, Mar 25
Avianca Logo
3:20 am - 3:20 pm
PTY
-
GRU
10h 00m1 stop
Avianca Logo
4:10 am - 8:55 am
GRU
-
PTY
30h 45m1 stop
$552Avianca
Thu, May 7 - Mon, May 11
Copa Airlines Logo
11:45 am - 8:50 pm
PTY
-
GRU
7h 05mnonstop
Copa Airlines Logo
5:25 am - 10:07 am
GRU
-
PTY
6h 42mnonstop
$562Copa Airlines
Wed, Jan 14 - Wed, Jan 28
Avianca Logo
2:55 am - 4:15 pm
PTY
-
GRU
11h 20m1 stop
Avianca Logo
7:35 am - 4:55 pm
GRU
-
PTY
11h 20m1 stop
$571Avianca
Mon, Jan 19 - Tue, Mar 10

Avianca flights from Panama City to Sao Paulo Guarulhos Intl Airport

Our best Avianca deals on Panama City to Sao Paulo Guarulhos Intl Airport flight tickets
Avianca
May 10
PTY3:20 amPanama City Tocumen Intl
10h 00m
1 stop
GRU3:20 pmSao Paulo Guarulhos Intl
May 13
GRU7:20 amSao Paulo Guarulhos Intl
11h 10m
1 stop
PTY4:30 pmPanama City Tocumen Intl
$500
Find similar
Avianca
Jan 21
PTY9:45 amPanama City Tocumen Intl
10h 55m
1 stop
GRU10:40 pmSao Paulo Guarulhos Intl
Mar 10
GRU7:35 amSao Paulo Guarulhos Intl
11h 20m
1 stop
PTY4:55 pmPanama City Tocumen Intl
$519
Find similar
Avianca
May 21
PTY9:55 amPanama City Tocumen Intl
12h 45m
1 stop
GRU12:40 amSao Paulo Guarulhos Intl
May 25
GRU4:10 amSao Paulo Guarulhos Intl
14h 20m
1 stop
PTY4:30 pmPanama City Tocumen Intl
$522
Find similar

Copa Airlines flights from Panama City to Sao Paulo Guarulhos Intl Airport

Our best Copa Airlines deals on Panama City to Sao Paulo Guarulhos Intl Airport flight tickets
Copa Airlines
Mar 19
PTY9:46 pmPanama City Tocumen Intl
6h 44m
GRU6:30 amSao Paulo Guarulhos Intl
Mar 25
GRU3:10 amSao Paulo Guarulhos Intl
6h 49m
PTY7:59 amPanama City Tocumen Intl
$529
Find similar
Copa Airlines
May 25
PTY12:00 pmPanama City Tocumen Intl
6h 50m
GRU8:50 pmSao Paulo Guarulhos Intl
May 31
GRU11:10 amSao Paulo Guarulhos Intl
6h 58m
PTY4:08 pmPanama City Tocumen Intl
$538
Find similar
Copa Airlines
Feb 1
PTY6:52 pmPanama City Tocumen Intl
6h 58m
GRU3:50 amSao Paulo Guarulhos Intl
Feb 7
GRU5:25 amSao Paulo Guarulhos Intl
6h 47m
PTY10:12 amPanama City Tocumen Intl
$562
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Sao Paulo Guarulhos Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Panama City to Sao Paulo Guarulhos Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Sun 5/10

3:20 am-3:20 pm

1 stop10h 00m

Sao Paulo Guarulhos Intl

Wed 5/13

7:20 am-4:30 pm

1 stop11h 10m

$500

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Wed 1/21

9:45 am-10:40 pm

1 stop10h 55m

Sao Paulo Guarulhos Intl

Tue 3/10

7:35 am-4:55 pm

1 stop11h 20m

$519

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Thu 5/21

9:55 am-2:10 am

1 stop14h 15m

Sao Paulo Guarulhos Intl

Mon 5/25

4:50 pm-12:45 am

1 stop9h 55m

$522

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Tue 4/14

3:20 am-3:20 pm

1 stop10h 00m

Sao Paulo Guarulhos Intl

Sat 4/18

4:50 pm-12:10 am

1 stop9h 20m

$528

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Thu 3/19

9:46 pm-6:30 am

Nonstop6h 44m

Sao Paulo Guarulhos Intl

Wed 3/25

3:10 am-7:59 am

Nonstop6h 49m

$529

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Thu 5/21

3:20 pm-12:10 am

Nonstop6h 50m

Sao Paulo Guarulhos Intl

Mon 5/25

5:25 am-10:23 am

Nonstop6h 58m

$538

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Thu 3/19

9:45 am-1:35 am

1 stop13h 50m

Sao Paulo Guarulhos Intl

Wed 3/25

1:20 am-4:55 pm

1 stop17h 35m

$541

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Thu 5/7

3:20 am-3:20 pm

1 stop10h 00m

Sao Paulo Guarulhos Intl

Mon 5/11

4:10 am-8:55 am

1 stop30h 45m

$552

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Wed 1/14

11:45 am-8:50 pm

Nonstop7h 05m

Sao Paulo Guarulhos Intl

Wed 1/28

5:25 am-10:07 am

Nonstop6h 42m

$562

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Mon 1/19

2:55 am-4:15 pm

1 stop11h 20m

Sao Paulo Guarulhos Intl

Tue 3/10

7:35 am-4:55 pm

1 stop11h 20m

$571

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Sao Paulo from

How to get the cheapest flight ticket from Panama City to Sao Paulo Guarulhos Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Sao Paulo Guarulhos Intl Airport?

In general, August is the cheapest month to fly from Panama City to Sao Paulo Guarulhos Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $405. If you don’t want to visit Sao Paulo Guarulhos Intl Airport in August, then you should wait until October to fly from Panama City, when ticket prices are also cheap, with an average price of $443.

What is the cheapest day to depart on your flight to Sao Paulo Guarulhos Intl Airport?

On average, the least expensive day to fly to Sao Paulo Guarulhos Intl Airport from Panama City is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $485. However, this price may fluctuate depending on the airline, the season, and holidays. The most expensive day to fly to Sao Paulo Guarulhos Intl Airport is Sunday, with ticket prices averaging around $732.

What is the cheapest time of day to depart on your flight to Sao Paulo Guarulhos Intl Airport?

Our data shows that the cheapest Panama City to Sao Paulo Guarulhos Intl Airport flights are usually those with departure times in the afternoon. Our users have found flights to Sao Paulo Guarulhos Intl Airport in the afternoon for as low as $495. Flights in the evening are often more expensive with an average ticket price of $588.

What is the cheapest Panama City Tocumen Intl to Sao Paulo Guarulhos Intl flight route?

Fly from Panama City Tocumen Intl to Sao Paulo Guarulhos Intl for the best Panama City Tocumen Intl - Sao Paulo Guarulhos Intl flight prices

How far in advance should I book a flight to Sao Paulo Guarulhos Intl Airport?

You are more likely to see cheaper flights to Sao Paulo Guarulhos Intl Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Sao Paulo Guarulhos Intl Airport for around $473 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Sao Paulo Guarulhos Intl Airport from Panama City for as low as $340 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Sao Paulo Guarulhos Intl flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Sao Paulo Guarulhos Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Sao Paulo Guarulhos Intl Airport flights?

You could potentially save up to 65% on your flight if you consider stops on a Panama City to Sao Paulo Guarulhos Intl Airport flight.

How have Panama City to Sao Paulo Guarulhos Intl Airport flight prices changed over time?

As of December 2025, prices for Panama City to Sao Paulo Guarulhos Intl Airport flights are approximately 10% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Sao Paulo Guarulhos Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Sao Paulo Guarulhos Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Sao Paulo Guarulhos Intl Airport (PTY to GRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Sao Paulo Guarulhos Intl Airport

Best Price Found

$1,434

Fastest flight time

6h 44m

Direct flights

Every day
The best one-way flight to Sao Paulo Guarulhos Intl Airport from Panama City in the past 72 hours is $1,434. The best round-trip flight deal from Panama City to Sao Paulo Guarulhos Intl Airport found on momondo in the last 72 hours is $529.
The fastest flight from Panama City to Sao Paulo Guarulhos Intl Airport takes 6h 44m
Direct flights go from Panama City to Sao Paulo Guarulhos Intl Airport every day.
Search flight deals

  • How far is Panama City Tocumen Intl to Sao Paulo Guarulhos Intl by plane?

    The straight-line distance from Panama City Tocumen Intl to Sao Paulo Guarulhos Intl is 3160.2 mi. By plane, this route typically takes 6h 44m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Sao Paulo Guarulhos Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Sao Paulo Guarulhos Intl Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Sao Paulo Guarulhos Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Sao Paulo Guarulhos Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Sao Paulo Guarulhos Intl Airport.

  • What documentation or ID do you need to fly to Sao Paulo Guarulhos Intl Airport?

    The travel and health documents required for your trip to Sao Paulo Guarulhos Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Sao Paulo Guarulhos Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Panama City to Sao Paulo Guarulhos Intl Airport?

  • What is the most popular airline from Panama City to Sao Paulo Guarulhos Intl Airport?

Best airlines flying from Panama City to Sao Paulo Guarulhos Intl Airport

Compare and see reviews for airlines that fly from Panama City to Sao Paulo Guarulhos Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $259Free CancellationRating
6.6
2,490 reviews
Search Avianca flights
Copa AirlinesPriceFrom $346Free CancellationRating
7.6
1,556 reviews
Search Copa Airlines flights

  • Copa Airlines Flights From Panama City to Sao Paulo Guarulhos Intl Airport

    Copa Airlines operates around 36 flights from Panama City to Sao Paulo Guarulhos Intl Airport every week. The average price of these flights found in the last 72 hours has been $496, but momondo users have found Copa Airlines deals from Panama City to Sao Paulo Guarulhos Intl Airport from as low as $346 round-trip. Copa Airlines has been scored 7.6/10 in 1,556 reviews.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Guarulhos
Santos
Guarujá
Campinas
Aparecida

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Sao Paulo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Sao Paulo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Sao Paulo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Sao Paulo from Panama City with this policy.

How can momondo help me find flights from Panama City to Sao Paulo?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Panama City to Sao Paulo.

I’m not ready to book a flight from Panama City to Sao Paulo right now. Can momondo alert me if prices change?

Price alerts on flights to Sao Paulo from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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