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Cheap flights from Panama City to Sao Paulo from $263

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Sao Paulo departing on 3/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
2:55 am - 4:15 pmPTY-GRU
11h 20m1 stop
Avianca Logo
7:35 am - 4:55 pmGRU-PTY
11h 20m1 stop
$444Avianca
Find Deal
Wed, Nov 19 - Sun, Nov 23
Avianca Logo
2:55 am - 4:15 pmPTY-GRU
11h 20m1 stop
Avianca Logo
7:35 am - 4:55 pmGRU-PTY
11h 20m1 stop
$481Avianca
Find Deal
Mon, Nov 10 - Sun, Nov 16
Copa Airlines Logo
6:54 pm - 3:50 amPTY-GRU
6h 56mnonstop
Copa Airlines Logo
3:10 am - 8:11 amGRU-PTY
7h 01mnonstop
$485Copa Airlines
Find Deal
Tue, Nov 11 - Sat, Nov 15
Multiple Airlines Logo
2:55 am - 4:15 pmPTY-GRU
11h 20m1 stop
Multiple Airlines Logo
7:35 am - 8:50 amGRU-PTY
27h 15m1 stop
$500Multiple Airlines
Find Deal
Mon, Mar 2 - Thu, Mar 12
Copa Airlines Logo
11:57 am - 8:50 pmPTY-GRU
6h 53mnonstop
Copa Airlines Logo
5:30 am - 10:12 amGRU-PTY
6h 42mnonstop
$502Copa Airlines
Find Deal
Tue, Dec 9 - Tue, Jan 13
Multiple Airlines Logo
2:55 am - 4:15 pmPTY-GRU
11h 20m1 stop
Multiple Airlines Logo
1:20 am - 2:00 pmGRU-PTY
14h 40m1 stop
$503Multiple Airlines
Find Deal
Fri, Feb 13 - Tue, Feb 17
Avianca Logo
2:55 pm - 5:40 amPTY-GRU
12h 45m1 stop
Avianca Logo
7:35 am - 4:55 pmGRU-PTY
11h 20m1 stop
$504Avianca
Find Deal
Tue, Nov 11 - Sun, Nov 16
Copa Airlines Logo
3:19 pm - 12:15 amPTY-GRU
6h 56mnonstop
Copa Airlines Logo
3:10 am - 8:11 amGRU-PTY
7h 01mnonstop
$516Copa Airlines
Find Deal
Tue, Nov 25 - Wed, Dec 3
Multiple Airlines Logo
2:55 am - 4:15 pmPTY-GRU
11h 20m1 stop
Multiple Airlines Logo
1:45 am - 10:10 amGRU-PTY
10h 25m1 stop
$519Multiple Airlines
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Sun, Mar 15 - Tue, Mar 31
Copa Airlines Logo
3:19 pm - 12:15 amPTY-GRU
6h 56mnonstop
Copa Airlines Logo
3:10 am - 8:11 amGRU-PTY
7h 01mnonstop
$527Copa Airlines
Find Deal
Tue, Nov 25 - Wed, Dec 3

Avianca flights from Panama City to Sao Paulo Guarulhos Intl Airport

Our best Avianca deals on Panama City to Sao Paulo Guarulhos Intl Airport flight tickets
Avianca
Nov 4
PTY2:55 amPanama City Tocumen Intl
17h 45m
1 stop
GRU10:40 pmSao Paulo Guarulhos Intl
Nov 8
GRU2:40 amSao Paulo Guarulhos Intl
13h 20m
1 stop
PTY2:00 pmPanama City Tocumen Intl
$436
Find similar
Avianca
Nov 19
PTY2:55 amPanama City Tocumen Intl
11h 20m
1 stop
GRU4:15 pmSao Paulo Guarulhos Intl
Nov 23
GRU7:35 amSao Paulo Guarulhos Intl
11h 20m
1 stop
PTY4:55 pmPanama City Tocumen Intl
$444
Find similar
Avianca
Nov 10
PTY2:55 amPanama City Tocumen Intl
11h 20m
1 stop
GRU4:15 pmSao Paulo Guarulhos Intl
Nov 16
GRU7:35 amSao Paulo Guarulhos Intl
11h 20m
1 stop
PTY4:55 pmPanama City Tocumen Intl
$481
Find similar

Copa Airlines flights from Panama City to Sao Paulo Guarulhos Intl Airport

Our best Copa Airlines deals on Panama City to Sao Paulo Guarulhos Intl Airport flight tickets
Copa Airlines
Nov 11
PTY6:54 pmPanama City Tocumen Intl
6h 56m
GRU3:50 amSao Paulo Guarulhos Intl
Nov 15
GRU3:10 amSao Paulo Guarulhos Intl
7h 01m
PTY8:11 amPanama City Tocumen Intl
$485
Find similar
Copa Airlines
Dec 9
PTY11:57 amPanama City Tocumen Intl
6h 53m
GRU8:50 pmSao Paulo Guarulhos Intl
Jan 13
GRU5:30 amSao Paulo Guarulhos Intl
6h 42m
PTY10:12 amPanama City Tocumen Intl
$502
Find similar
Copa Airlines
Nov 25
PTY3:19 pmPanama City Tocumen Intl
6h 56m
GRU12:15 amSao Paulo Guarulhos Intl
Dec 3
GRU3:10 amSao Paulo Guarulhos Intl
7h 01m
PTY8:11 amPanama City Tocumen Intl
$516
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Panama City to Sao Paulo Guarulhos Intl Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Panama City to Sao Paulo Guarulhos Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Wed 11/19

2:55 am-4:15 pm

1 stop11h 20m

Sao Paulo Guarulhos Intl

Sun 11/23

7:35 am-4:55 pm

1 stop11h 20m

$444

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Mon 11/10

2:55 am-4:15 pm

1 stop11h 20m

Sao Paulo Guarulhos Intl

Sun 11/16

7:35 am-4:55 pm

1 stop11h 20m

$481

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Tue 11/11

6:54 pm-3:50 am

Nonstop6h 56m

Sao Paulo Guarulhos Intl

Sat 11/15

3:10 am-8:11 am

Nonstop7h 01m

$485

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Mon 3/2

2:55 am-4:15 pm

1 stop11h 20m

Sao Paulo Guarulhos Intl

Thu 3/12

7:35 am-8:50 am

1 stop27h 15m

$500

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Tue 12/9

11:57 am-8:50 pm

Nonstop6h 53m

Sao Paulo Guarulhos Intl

Tue 1/13

5:30 am-10:12 am

Nonstop6h 42m

$502

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Fri 2/13

2:55 am-4:15 pm

1 stop11h 20m

Sao Paulo Guarulhos Intl

Tue 2/17

1:20 am-2:00 pm

1 stop14h 40m

$503

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Tue 11/11

2:55 pm-5:40 am

1 stop12h 45m

Sao Paulo Guarulhos Intl

Sun 11/16

7:35 am-4:55 pm

1 stop11h 20m

$504

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Tue 11/25

3:19 pm-12:15 am

Nonstop6h 56m

Sao Paulo Guarulhos Intl

Wed 12/3

3:10 am-8:11 am

Nonstop7h 01m

$516

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Sun 3/15

2:55 am-4:15 pm

1 stop11h 20m

Sao Paulo Guarulhos Intl

Tue 3/31

1:45 am-10:10 am

1 stop10h 25m

$519

Panama CitySao Paulo

PTY - GRU

PTYGRU

Panama City Tocumen Intl

Tue 11/25

3:19 pm-12:15 am

Nonstop6h 56m

Sao Paulo Guarulhos Intl

Wed 12/3

3:10 am-8:11 am

Nonstop7h 01m

$527

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Panama City to Sao Paulo Guarulhos Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Sao Paulo Guarulhos Intl Airport?

In general, August is the cheapest month to fly from Panama City to Sao Paulo Guarulhos Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $405. If you don’t want to visit Sao Paulo Guarulhos Intl Airport in August, then you should wait until October to fly from Panama City, when ticket prices are also cheap, with an average price of $446.

What is the cheapest day to depart on your flight to Sao Paulo Guarulhos Intl Airport?

On average, the least expensive day to fly to Sao Paulo Guarulhos Intl Airport from Panama City is on a Wednesday. momondo users have found tickets for Wednesday departures for as low as $444. However, this price may fluctuate depending on the airline, the season, and holidays. The most expensive day to fly to Sao Paulo Guarulhos Intl Airport is Friday, with ticket prices averaging around $739.

What is the cheapest time of day to depart on your flight to Sao Paulo Guarulhos Intl Airport?

Our data shows that the cheapest Panama City to Sao Paulo Guarulhos Intl Airport flights are usually those with departure times in the morning. Our users have found flights to Sao Paulo Guarulhos Intl Airport in the morning for as low as $534. Flights in the evening are often more expensive with an average ticket price of $620.

What is the cheapest Panama City Tocumen Intl to Sao Paulo Guarulhos Intl flight route?

Fly from Panama City Tocumen Intl to Sao Paulo Guarulhos Intl for the best Panama City Tocumen Intl - Sao Paulo Guarulhos Intl flight prices

How far in advance should I book a flight to Sao Paulo Guarulhos Intl Airport?

You are more likely to see cheaper flights to Sao Paulo Guarulhos Intl Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Sao Paulo Guarulhos Intl Airport for around $480 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Sao Paulo Guarulhos Intl Airport from Panama City for as low as $314 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Sao Paulo Guarulhos Intl flights?

There are 2 cabin classes available to choose from on Panama City Tocumen Intl to Sao Paulo Guarulhos Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Sao Paulo Guarulhos Intl Airport flights?

No. A direct flight is the cheapest option for a flight between Panama City to Sao Paulo Guarulhos Intl Airport.

How have Panama City to Sao Paulo Guarulhos Intl Airport flight prices changed over time?

As of October 2025, prices for Panama City to Sao Paulo Guarulhos Intl Airport flights are approximately 13% cheaper when compared to flights at the same time last year.

When to book flights from Panama City to Sao Paulo Guarulhos Intl Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Sao Paulo Guarulhos Intl Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City to Sao Paulo Guarulhos Intl Airport (PTY to GRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Sao Paulo Guarulhos Intl Airport

Best Price Found

$1,434

Fastest flight time

6h 40m

Direct flights

Every day
The best one-way flight to Sao Paulo Guarulhos Intl Airport from Panama City in the past 72 hours is $1,434. The best round-trip flight deal from Panama City to Sao Paulo Guarulhos Intl Airport found on momondo in the last 72 hours is $416.
The fastest flight from Panama City to Sao Paulo Guarulhos Intl Airport takes 6h 40m
Direct flights go from Panama City to Sao Paulo Guarulhos Intl Airport every day.
Search flight deals

  • How far is Panama City Tocumen Intl to Sao Paulo Guarulhos Intl by plane?

    The straight-line distance from Panama City Tocumen Intl to Sao Paulo Guarulhos Intl is 3160.2 mi. By plane, this route typically takes 6h 40m.

  • When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Sao Paulo Guarulhos Intl Airport?

    Prices for flights from Panama City Tocumen Intl Airport to Sao Paulo Guarulhos Intl Airport refresh daily.

  • How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Sao Paulo Guarulhos Intl Airport?

  • How old do you have to be to fly from Panama City Tocumen Intl Airport to Sao Paulo Guarulhos Intl Airport?

    Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Sao Paulo Guarulhos Intl Airport.

  • What documentation or ID do you need to fly to Sao Paulo Guarulhos Intl Airport?

    The travel and health documents required for your trip to Sao Paulo Guarulhos Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Sao Paulo Guarulhos Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Panama City to Sao Paulo Guarulhos Intl Airport?

  • What is the most popular airline from Panama City to Sao Paulo Guarulhos Intl Airport?

Best airlines flying from Panama City to Sao Paulo Guarulhos Intl Airport

Compare and see reviews for airlines that fly from Panama City to Sao Paulo Guarulhos Intl Airport with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $338Free CancellationRating
6.6
2,467 reviews
Search Avianca flights
Copa AirlinesPriceFrom $346Free CancellationRating
7.6
1,561 reviews
Search Copa Airlines flights

  • Copa Airlines Flights From Panama City to Sao Paulo Guarulhos Intl Airport

    Copa Airlines operates around 12 flights from Panama City to Sao Paulo Guarulhos Intl Airport every week. The average price of these flights found in the last 72 hours has been $501, but momondo users have found Copa Airlines deals from Panama City to Sao Paulo Guarulhos Intl Airport from as low as $346 round-trip. Copa Airlines has been scored 7.6/10 in 1,561 reviews.

Traveling to a place near Sao Paulo?

Book flights to Sao Paulo if you plan to visit one of these locations
Guarulhos
Santos
Campinas
Guarujá
Aparecida

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Sao Paulo?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Panama City to Sao Paulo. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Panama City to Sao Paulo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Sao Paulo from Panama City with this policy.

How can momondo help me find flights from Panama City to Sao Paulo?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Panama City to Sao Paulo.

I’m not ready to book a flight from Panama City to Sao Paulo right now. Can momondo alert me if prices change?

Price alerts on flights to Sao Paulo from Panama City are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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