Cheap flights from Panama City to Sao Paulo from $252

In general, December is the cheapest month to fly from Panama City to Sao Paulo Guarulhos Intl Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $366. If you don’t want to visit Sao Paulo Guarulhos Intl Airport in December, then you should wait until October to fly from Panama City, when ticket prices are also cheap, with an average price of $443.

On average, the least expensive day to fly to Sao Paulo Guarulhos Intl Airport from Panama City is on a Monday. momondo users have found tickets for Monday departures for as low as $529. However, this price may fluctuate depending on the airline, the season, and holidays. The most expensive day to fly to Sao Paulo Guarulhos Intl Airport is Friday, with ticket prices averaging around $739.

Our data shows that the cheapest Panama City to Sao Paulo Guarulhos Intl Airport flights are usually those with departure times in the morning. Our users have found flights to Sao Paulo Guarulhos Intl Airport in the morning for as low as $538. Flights in the evening are often more expensive with an average ticket price of $684.

Fly from Panama City Tocumen Intl to Sao Paulo Guarulhos Intl for the best Panama City Tocumen Intl - Sao Paulo Guarulhos Intl flight prices

You are more likely to see cheaper flights to Sao Paulo Guarulhos Intl Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Sao Paulo Guarulhos Intl Airport for around $526 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Sao Paulo Guarulhos Intl Airport from Panama City for as low as $367 on momondo.

There are 3 cabin classes available to choose from on Panama City to Sao Paulo Guarulhos Intl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 60% on your flight if you consider stops on a Panama City to Sao Paulo Guarulhos Intl Airport flight.

As of August 2026, prices for Panama City to Sao Paulo Guarulhos Intl Airport flights are approximately 3% cheaper when compared to flights at the same time last year.

16 flights are operational daily from Panama City to Sao Paulo Guarulhos Intl Airport as of August 2026. The most popular departure time for this route is 3:00PM, with 52% of flights per day taking off in the afternoon.

As of August 2026, there are 117 flights per week flying from Panama City to Sao Paulo Guarulhos Intl Airport. The most common day of the week flights depart is Wed, with 19% of flights taking off on this day.