Cheap flights from Panama City to Frankfurt am Main from $509

In general, November is the cheapest month to fly from Panama City to Frankfurt am Main Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $796. If you aren’t able to travel to Frankfurt am Main Airport during the month of November, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $802.

On average, the least expensive day to fly to Frankfurt am Main Airport from Panama City is on a Thursday. momondo users have found tickets for Thursday departures for as low as $563. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from Panama City to Frankfurt am Main Airport on a Saturday will generally be more expensive and average around $1,196. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

According to our data, the cheapest time of day to fly to Frankfurt am Main Airport is in the morning. momondo users have found flights departing from Panama City to Frankfurt am Main Airport in the morning for as low as $610. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In contrast, the most expensive time of day to depart to Frankfurt am Main Airport is in the afternoon when prices are around $950.

Fly from Panama City Tocumen Intl to Frankfurt am Main for the best Panama City Tocumen Intl - Frankfurt am Main flight prices

You are more likely to see cheaper flights to Frankfurt am Main Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Frankfurt am Main Airport for around $883 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Frankfurt am Main Airport from Panama City for as low as $761 on momondo.

You could potentially save up to 29% on your flight if you consider stops on a Panama City to Frankfurt am Main Airport flight.

As of May 2026, prices for Panama City to Frankfurt am Main Airport flights are approximately 12% cheaper when compared to flights at the same time last year.

Air Europa is the most popular carrier operating from Panama City Tocumen Intl to Frankfurt am Main

KLM, Condor and Air Europa are the top three most popular airlines that fly to Frankfurt am Main Airport from Panama City according to our data. KLM is the first choice among our users, with 32% of people opting to fly with this airline when traveling to Frankfurt am Main Airport. Keep in mind that there are 4 different airlines that fly to Frankfurt am Main Airport on a routine basis, so you have a few additional options to choose from.

Historically, on average around 7% of flights between Panama City and Frankfurt am Main have experienced a delay on any given week. The average delay length over the past 12 months has been 149 minutes.

Generally, flights departing in the morning tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Thursday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

According to our data, Condor have had the least number of delays on this route over the last 12 months; with about 7% of their flights experiencing any sort of delay.

Madrid (MAD) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Madrid (MAD) offer the lowest average round-trip price of $1,295.

Flights connecting via Madrid (MAD) have the shortest average one-way travel time: 14h 25m.

Madrid (MAD) has the shortest average layover time for this route: 1h 40m.