Which airport is the most popular layover for flights between Panama City and Frankfurt am Main Airport?

Madrid (MAD) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

How many flights depart from Panama City to Frankfurt am Main Airport on average per week?

As of December 2025, 2 flights take off from Panama City and land in Frankfurt am Main Airport each week. The most common flight departure day for this route is Mon, with 50% of weekly flights taking off on this day.

What day of the week experiences the fewest flight delays on this route?

Monday is statistically the day of the week which experiences the fewest number of delays on this flight route. Thursday has historically seen more delays on average compared to the rest of the week.

What is the most punctual flight time for Panama City to Frankfurt am Main flights?

Generally, flights departing in the morning tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Which layover airport has the shortest connection time from Panama City to Frankfurt am Main Airport?

Paris (CDG) has the shortest average layover time for this route: 2h 55m.

Which layover airport offers the lowest fares from Panama City to Frankfurt am Main Airport?

Flights via Madrid (MAD) offer the lowest average round-trip price of $994.

Which layover airport has the shortest travel time from Panama City to Frankfurt am Main Airport?

Flights connecting via Paris (CDG) have the shortest average one-way travel time: 14h 50m.

What is the cheapest airline that flies from Panama City Tocumen Intl to Frankfurt am Main?

Condor and Avianca are the most popular carriers operating from Panama City Tocumen Intl to Frankfurt am Main

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Frankfurt am Main Airport?

Prices for flights from Panama City Tocumen Intl Airport to Frankfurt am Main Airport refresh daily.

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Frankfurt am Main Airport?

As of December 2025, there are 2 operators available to choose from for flights from Panama City Tocumen Intl Airport to Frankfurt am Main Airport.

How old do you have to be to fly from Panama City Tocumen Intl Airport to Frankfurt am Main Airport?

Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Frankfurt am Main Airport.

What documentation or ID do you need to fly to Frankfurt am Main Airport?

The necessary travel and health documents for your Frankfurt am Main Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

$456 Cheap Flights from Panama City to Frankfurt am Main Airport in 2025/26

Q: How often are flights from Panama City to Frankfurt am Main delayed?

Historically, on average around 0% of flights between Panama City and Frankfurt am Main have experienced a delay on any given week. The average delay length over the past 12 months has been 0 minutes.

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Enter your travel dates to find the best prices.

6:50 pm - 9:35 am

PTY

FRA

31h 45m1 stop

2:15 pm - 4:50 pm

FRA

PTY

33h 35m1 stop

$817KLM

Thu, Apr 23 - Tue, May 19

3:20 pm - 8:40 am

PTY

FRA

35h 20m1 stop

12:00 pm - 8:10 pm

FRA

PTY

14h 10m1 stop

$819Air France

Thu, Mar 5 - Wed, Mar 18

3:20 pm - 8:40 am

PTY

FRA

35h 20m1 stop

9:40 am - 8:10 pm

FRA

PTY

16h 30m1 stop

$824Air France

Thu, Mar 5 - Wed, Mar 18

3:20 pm - 8:40 am

PTY

FRA

35h 20m1 stop

9:40 am - 8:10 pm

FRA

PTY

16h 30m1 stop

$825Air France

Thu, Mar 5 - Wed, Mar 18

6:45 pm - 11:05 am

PTY

FRA

34h 20m1 stop

9:50 am - 8:00 pm

FRA

PTY

16h 10m1 stop

$826Multiple Airlines

Thu, Dec 25 - Tue, Dec 30

8:25 pm - 5:50 pm

PTY

FRA

14h 25m1 stop

10:55 am - 6:40 pm

FRA

PTY

14h 45m1 stop

$834Air Europa

Sun, May 17 - Sun, May 31

10:05 pm - 10:25 pm

PTY

FRA

18h 20m1 stop

9:40 am - 8:10 pm

FRA

PTY

16h 30m1 stop

$846Multiple Airlines

Mon, Feb 2 - Tue, Feb 10

2:20 pm - 8:55 am

PTY

FRA

35h 35m1 stop

6:45 pm - 4:50 pm

FRA

PTY

29h 05m1 stop

$847Multiple Airlines

Tue, Apr 7 - Tue, Apr 14

10:20 pm - 10:05 pm

PTY

FRA

17h 45m1 stop

12:00 pm - 8:10 pm

FRA

PTY

14h 10m1 stop

$848Air France

Wed, Mar 11 - Wed, Mar 18

3:20 pm - 8:40 am

PTY

FRA

35h 20m1 stop

9:40 am - 8:10 pm

FRA

PTY

16h 30m1 stop

$849Air France

Thu, Feb 5 - Tue, Feb 10

Air France flights from Panama City to Frankfurt am Main Airport

Our best Air France deals on Panama City to Frankfurt am Main Airport flight tickets

Air France

Mar 5

PTY3:20 pmPanama City Tocumen Intl

35h 20m

1 stop

FRA8:40 amFrankfurt am Main

Mar 18

FRA12:00 pmFrankfurt am Main

14h 10m

1 stop

PTY8:10 pmPanama City Tocumen Intl

$819

Find similar

Air France

Mar 5

PTY3:20 pmPanama City Tocumen Intl

35h 20m

1 stop

FRA8:40 amFrankfurt am Main

Mar 18

FRA9:40 amFrankfurt am Main

16h 30m

1 stop

PTY8:10 pmPanama City Tocumen Intl

$824

Find similar

Air France

Mar 5

PTY3:20 pmPanama City Tocumen Intl

35h 20m

1 stop

FRA8:40 amFrankfurt am Main

Mar 18

FRA9:40 amFrankfurt am Main

16h 30m

1 stop

PTY8:10 pmPanama City Tocumen Intl

$825

Find similar

Air Europa flights from Panama City to Frankfurt am Main Airport

Our best Air Europa deals on Panama City to Frankfurt am Main Airport flight tickets

Air Europa

May 17

PTY8:25 pmPanama City Tocumen Intl

14h 25m

1 stop

FRA5:50 pmFrankfurt am Main

May 31

FRA10:55 amFrankfurt am Main

14h 45m

1 stop

PTY6:40 pmPanama City Tocumen Intl

$834

Find similar

Air Europa

Apr 28

PTY8:25 pmPanama City Tocumen Intl

14h 25m

1 stop

FRA5:50 pmFrankfurt am Main

May 19

FRA10:55 amFrankfurt am Main

14h 45m

1 stop

PTY6:40 pmPanama City Tocumen Intl

$908

Find similar

Air Europa

May 3

PTY8:25 pmPanama City Tocumen Intl

14h 25m

1 stop

FRA5:50 pmFrankfurt am Main

May 20

FRA10:55 amFrankfurt am Main

14h 45m

1 stop

PTY6:40 pmPanama City Tocumen Intl

$941

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Panama City to Frankfurt am Main Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityFrankfurt am Main

PTY - FRA

PTYFRA

Panama City Tocumen Intl

Thu 4/23

6:50 pm-9:35 am

1 stop31h 45m

Frankfurt am Main

Tue 5/19

2:15 pm-4:50 pm

1 stop33h 35m

$817

Panama CityFrankfurt am Main

PTY - FRA

PTYFRA

Panama City Tocumen Intl

Thu 3/5

3:20 pm-8:40 am

1 stop35h 20m

Frankfurt am Main

Wed 3/18

12:00 pm-8:10 pm

1 stop14h 10m

$819

Panama CityFrankfurt am Main

PTY - FRA

PTYFRA

Panama City Tocumen Intl

Thu 3/5

3:20 pm-8:40 am

1 stop35h 20m

Frankfurt am Main

Wed 3/18

9:40 am-8:10 pm

1 stop16h 30m

$824

Panama CityFrankfurt am Main

PTY - FRA

PTYFRA

Panama City Tocumen Intl

Thu 3/5

3:20 pm-8:40 am

1 stop35h 20m

Frankfurt am Main

Wed 3/18

9:40 am-8:10 pm

1 stop16h 30m

$825

Panama CityFrankfurt am Main

PTY - FRA

PTYFRA

Panama City Tocumen Intl

Thu 12/25

6:45 pm-11:05 am

1 stop34h 20m

Frankfurt am Main

Tue 12/30

9:50 am-8:00 pm

1 stop16h 10m

$826

Panama CityFrankfurt am Main

PTY - FRA

PTYFRA

Panama City Tocumen Intl

Sun 5/17

8:25 pm-5:50 pm

1 stop14h 25m

Frankfurt am Main

Sun 5/31

10:55 am-6:40 pm

1 stop14h 45m

$834

Panama CityFrankfurt am Main

PTY - FRA

PTYFRA

Panama City Tocumen Intl

Mon 2/2

10:05 pm-10:25 pm

1 stop18h 20m

Frankfurt am Main

Tue 2/10

9:40 am-8:10 pm

1 stop16h 30m

$846

Panama CityFrankfurt am Main

PTY - FRA

PTYFRA

Panama City Tocumen Intl

Tue 4/7

2:20 pm-8:55 am

1 stop35h 35m

Frankfurt am Main

Tue 4/14

6:45 pm-4:50 pm

1 stop29h 05m

$847

Panama CityFrankfurt am Main

PTY - FRA

PTYFRA

Panama City Tocumen Intl

Wed 3/11

10:20 pm-10:05 pm

1 stop17h 45m

Frankfurt am Main

Wed 3/18

12:00 pm-8:10 pm

1 stop14h 10m

$848

Panama CityFrankfurt am Main

PTY - FRA

PTYFRA

Panama City Tocumen Intl

Thu 2/5

3:20 pm-8:40 am

1 stop35h 20m

Frankfurt am Main

Tue 2/10

9:40 am-8:10 pm

1 stop16h 30m

$849

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Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Panama City to Frankfurt am Main Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Delays

Layovers

Other information

What is the cheapest month to fly to Frankfurt am Main Airport?

In general, June is the cheapest month to fly from Panama City to Frankfurt am Main Airport. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $724. If you aren’t able to travel to Frankfurt am Main Airport during the month of June, then flying in October is also cheap. Prices for this month can be found on momondo for an average of $802.

What is the cheapest day to depart on your flight to Frankfurt am Main Airport?

On average, the least expensive day to fly to Frankfurt am Main Airport from Panama City is on a Thursday. momondo users have found tickets for Thursday departures for as low as $580. However, this price may fluctuate depending on the airline, the season, and holidays. Flights from Panama City to Frankfurt am Main Airport on a Saturday will generally be more expensive and average around $1,196. Keep in mind that these prices on both days could fluctuate depending on the season and the demand.

What is the cheapest time of day to depart on your flight to Frankfurt am Main Airport?

According to our data, the cheapest time of day to fly to Frankfurt am Main Airport is in the morning. momondo users have found flights departing from Panama City to Frankfurt am Main Airport in the morning for as low as $612. Keep in mind that these prices may fluctuate based on what airline you choose and the time of year you plan to travel. In contrast, the most expensive time of day to depart to Frankfurt am Main Airport is in the afternoon when prices are around $950.

What is the cheapest Panama City Tocumen Intl to Frankfurt am Main flight route?

Fly from Panama City Tocumen Intl to Frankfurt am Main for the best Panama City Tocumen Intl - Frankfurt am Main flight prices

How far in advance should I book a flight to Frankfurt am Main Airport?

You are more likely to see cheaper flights to Frankfurt am Main Airport from Panama City when booking weeks ahead of your departure date. In general, you can expect to find flights to Frankfurt am Main Airport for around $865 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Frankfurt am Main Airport from Panama City for as low as $525 on momondo.

What cabin class options are available on Panama City Tocumen Intl to Frankfurt am Main flights?

There are 3 cabin classes available to choose from on Panama City Tocumen Intl to Frankfurt am Main flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Frankfurt am Main Airport flights?

No. A direct flight is the cheapest option for a flight between Panama City to Frankfurt am Main Airport.

How have Panama City to Frankfurt am Main Airport flight prices changed over time?

As of December 2025, prices for Panama City to Frankfurt am Main Airport flights are approximately 89% more expensive when compared to flights at the same time last year.

When to book flights from Panama City to Frankfurt am Main Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City to Frankfurt am Main Airport according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Panama City to Frankfurt am Main Airport (PTY to FRA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Frankfurt am Main Airport

Best Price Found	$885
Fastest flight time	35h 20m
Direct flights	Tue and Fri

The best flight deal from Panama City to Frankfurt am Main Airport found on momondo in the last 72 hours is $885

The fastest flight from Panama City to Frankfurt am Main Airport takes 35h 20m

Direct flights go from Panama City to Frankfurt am Main Airport on Tuesday and Friday. There are no airlines offering direct flights.

Search flight deals

How far is Panama City Tocumen Intl to Frankfurt am Main by plane?
Frankfurt am Main is 5654.7 mi away from Panama City Tocumen Intl. Typically, this will take 35h 20m by plane in normal conditions.
When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Frankfurt am Main Airport?
Prices for flights from Panama City Tocumen Intl Airport to Frankfurt am Main Airport refresh daily.
How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Frankfurt am Main Airport?
As of December 2025, there are 2 operators available to choose from for flights from Panama City Tocumen Intl Airport to Frankfurt am Main Airport.
How old do you have to be to fly from Panama City Tocumen Intl Airport to Frankfurt am Main Airport?
Although the minimum age for a child to fly alone is five, airlines that offer an unaccompanied minor (UMNR) service may have their own age limits, which could be impacted by factors such as flight length, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Panama City Tocumen Intl Airport to Frankfurt am Main Airport.
What documentation or ID do you need to fly to Frankfurt am Main Airport?
The necessary travel and health documents for your Frankfurt am Main Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.
What is the most popular plane model from Panama City to Frankfurt am Main Airport?
momondo data reveals that the most frequently booked plane model on the route from Panama City to Frankfurt am Main Airport is Airbus A330-900neo, representing 51.26% of all bookings. The subsequent popular model is Airbus A350-900 at 48.74%.
What is the most popular airline from Panama City to Frankfurt am Main Airport?
Based on momondo bookings for this flight route, the most popular airline on flight routes from Panama City to Frankfurt am Main Airport is Condor (71% of total bookings). The next most popular airline is KLM (29%).

Best airlines flying from Panama City to Frankfurt am Main Airport

Compare and see reviews for airlines that fly from Panama City to Frankfurt am Main Airport with momondo

Airline	Rating	Free Cancellation	Price
Condor	PriceFrom $320	Free Cancellation	Rating 6.4 390 reviews		Search Condor flights
KLM	PriceFrom $725	Free Cancellation	Rating 7.7 1,432 reviews		Search KLM flights

Condor Flights From Panama City to Frankfurt am Main Airport
Condor flies from Panama City to Frankfurt am Main Airport around 2 times per week, with 390 momondo users rating the airline 6.4/10. The cheapest Condor deal from Panama City to Frankfurt am Main Airport in the last 72 hours was $320 (round-trip), much lower than the average airfare cost of $800 for Condor flights on this route.

Heidelberg

Baden-Baden

Mainz

Koblenz

Rothenburg ob der Tauber

Wurzburg

Trier

Darmstadt

Fulda

Kaiserslautern

Wiesbaden

Heilbronn

Marburg

Cochem

Rüdesheim am Rhein

Bernkastel-Kues

Nuerburg

Schweinfurt

Aschaffenburg

Bad Kissingen

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Frankfurt am Main?

Finding the right flight to Frankfurt am Main from Panama City is quick and easy when you have a range of options in front of you, from reputable agents and recognisable airlines. Options that can then be filtered down to find the best fit. That is what momondo does. We make finding flights to Frankfurt am Main quick and easy, saving you time and money.

Can I find flights from Panama City to Frankfurt am Main with flexible booking policies on momondo?

Flights from Panama City to Frankfurt am Main with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Panama City to Frankfurt am Main?

Once all potential Panama City to Frankfurt am Main flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Panama City to Frankfurt am Main right now. Can momondo alert me if prices change?

Yes momondo offers price alerts on flights to Frankfurt am Main from Panama City. After performing a search on this page you should be able to see the price alert set up feature. Simply provide a valid email address and momondo will instantly alert you when prices change.

An easier way to manage your Frankfurt am Main Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

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Cheap flights from Panama City to Frankfurt am Main from $612

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City to Frankfurt am Main departing on 3/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Air France flights from Panama City to Frankfurt am Main Airport

Our best Air France deals on Panama City to Frankfurt am Main Airport flight tickets

Air Europa flights from Panama City to Frankfurt am Main Airport

Our best Air Europa deals on Panama City to Frankfurt am Main Airport flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Panama City to Frankfurt am Main Airport that are best for you.

See travel insights to Frankfurt am Main from

How to get the cheapest flight ticket from Panama City to Frankfurt am Main Airport

What is the cheapest month to fly to Frankfurt am Main Airport?

What is the cheapest day to depart on your flight to Frankfurt am Main Airport?

What is the cheapest time of day to depart on your flight to Frankfurt am Main Airport?

What is the cheapest Panama City Tocumen Intl to Frankfurt am Main flight route?

Fly from Panama City Tocumen Intl to Frankfurt am Main for the best Panama City Tocumen Intl - Frankfurt am Main flight prices

How far in advance should I book a flight to Frankfurt am Main Airport?

What cabin class options are available on Panama City Tocumen Intl to Frankfurt am Main flights?

There are 3 cabin classes available to choose from on Panama City Tocumen Intl to Frankfurt am Main flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City to Frankfurt am Main Airport flights?

No. A direct flight is the cheapest option for a flight between Panama City to Frankfurt am Main Airport.

How have Panama City to Frankfurt am Main Airport flight prices changed over time?

As of December 2025, prices for Panama City to Frankfurt am Main Airport flights are approximately 89% more expensive when compared to flights at the same time last year.

What is the cheapest airline that flies from Panama City Tocumen Intl to Frankfurt am Main?

Condor and Avianca are the most popular carriers operating from Panama City Tocumen Intl to Frankfurt am Main

How often are flights from Panama City to Frankfurt am Main delayed?

Historically, on average around 0% of flights between Panama City and Frankfurt am Main have experienced a delay on any given week. The average delay length over the past 12 months has been 0 minutes.

What is the most punctual flight time for Panama City to Frankfurt am Main flights?

Generally, flights departing in the morning tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

What day of the week experiences the fewest flight delays on this route?

Monday is statistically the day of the week which experiences the fewest number of delays on this flight route. Thursday has historically seen more delays on average compared to the rest of the week.

Which airport is the most popular layover for flights between Panama City and Frankfurt am Main Airport?

Madrid (MAD) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Which layover airport offers the lowest fares from Panama City to Frankfurt am Main Airport?

Flights via Madrid (MAD) offer the lowest average round-trip price of $994.

Which layover airport has the shortest travel time from Panama City to Frankfurt am Main Airport?

Flights connecting via Paris (CDG) have the shortest average one-way travel time: 14h 50m.

Which layover airport has the shortest connection time from Panama City to Frankfurt am Main Airport?

Paris (CDG) has the shortest average layover time for this route: 2h 55m.

How many flights depart from Panama City to Frankfurt am Main Airport on average per week?

As of December 2025, 2 flights take off from Panama City and land in Frankfurt am Main Airport each week. The most common flight departure day for this route is Mon, with 50% of weekly flights taking off on this day.

When to book flights from Panama City to Frankfurt am Main Airport

Cheap Panama City to Frankfurt am Main Airport (PTY to FRA) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City to Frankfurt am Main Airport

Best Price Found

Fastest flight time

Direct flights

How far is Panama City Tocumen Intl to Frankfurt am Main by plane?

When did momondo last update prices for flights from Panama City Tocumen Intl Airport to Frankfurt am Main Airport?

How many operators does momondo search for flights from Panama City Tocumen Intl Airport to Frankfurt am Main Airport?

How old do you have to be to fly from Panama City Tocumen Intl Airport to Frankfurt am Main Airport?

What documentation or ID do you need to fly to Frankfurt am Main Airport?

What is the most popular plane model from Panama City to Frankfurt am Main Airport?

What is the most popular airline from Panama City to Frankfurt am Main Airport?

Best airlines flying from Panama City to Frankfurt am Main Airport

Compare and see reviews for airlines that fly from Panama City to Frankfurt am Main Airport with momondo

Condor Flights From Panama City to Frankfurt am Main Airport

Traveling to a place near Frankfurt am Main?

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Frankfurt am Main?

Can I find flights from Panama City to Frankfurt am Main with flexible booking policies on momondo?

How can momondo help me find flights from Panama City to Frankfurt am Main?

I’m not ready to book a flight from Panama City to Frankfurt am Main right now. Can momondo alert me if prices change?

An easier way to manage your Frankfurt am Main Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Frankfurt am Main