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Cheap flights from Panama City, Florida to Detroit from $150

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Detroit departing on 4/21. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Panama City, Florida to Detroit

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
1:50 pm - 6:55 pm
ECP
-
DTW
4h 05m
1 stop
Delta Logo
8:30 am - 2:04 pm
DTW
-
ECP
6h 34m
1 stop
$319Delta
Thu, May 28 - Sun, May 31
American Airlines Logo
4:16 pm - 12:33 am
ECP
-
DTW
7h 17m
1 stop
American Airlines Logo
10:12 am - 6:22 pm
DTW
-
ECP
9h 10m
2 stops
$324American Airlines
Tue, Jun 23 - Tue, Jul 14
Southwest Logo
7:20 am - 3:00 pm
ECP
-
DTW
6h 40m
1 stop
Southwest Logo
6:15 am - 9:00 am
DTW
-
ECP
3h 45m
1 stop
$335Southwest
Sat, Apr 25 - Sat, May 2
Southwest Logo
7:20 am - 3:00 pm
ECP
-
DTW
6h 40m
1 stop
Southwest Logo
6:15 am - 2:30 pm
DTW
-
ECP
9h 15m
2 stops
$340Southwest
Sat, Apr 25 - Sat, May 2
Southwest Logo
12:40 pm - 11:25 pm
ECP
-
DTW
9h 45m
2 stops
Southwest Logo
5:50 am - 12:50 pm
DTW
-
ECP
8h 00m
2 stops
$345Southwest
Sat, Apr 25 - Sat, May 2
American Airlines Logo
4:40 pm - 12:25 am
ECP
-
DTW
6h 45m
1 stop
American Airlines Logo
6:00 am - 10:03 am
DTW
-
ECP
5h 03m
1 stop
$349American Airlines
Mon, May 4 - Fri, May 15
Delta Logo
5:49 am - 11:02 am
ECP
-
DTW
4h 13m
1 stop
Delta Logo
5:20 am - 8:35 am
DTW
-
ECP
4h 15m
1 stop
$369Delta
Fri, Apr 24 - Sun, May 3
United Airlines Logo
4:57 pm - 11:57 pm
ECP
-
DTW
6h 00m
1 stop
United Airlines Logo
7:18 am - 1:23 pm
DTW
-
ECP
7h 05m
1 stop
$379United Airlines
Tue, Apr 28 - Wed, Apr 29
Southwest Logo
5:25 pm - 10:20 pm
ECP
-
DTW
3h 55m
1 stop
Southwest Logo
1:00 pm - 6:20 pm
DTW
-
ECP
6h 20m
2 stops
$384Southwest
Mon, May 4 - Fri, May 15
Delta Logo
1:33 pm - 6:39 pm
ECP
-
DTW
4h 06m
1 stop
Delta Logo
2:05 pm - 6:00 pm
DTW
-
ECP
4h 55m
1 stop
$389Delta
Wed, Apr 22 - Tue, May 5

United Airlines flights from Panama City, Florida to Detroit Metropolitan Wayne County Airport

Our best United Airlines deals on Panama City, Florida to Detroit Metropolitan Wayne County Airport flight tickets
United Airlines
Apr 28
ECP4:57 pmPanama City NW Florida Beaches
6h 00m
1 stop
DTW11:57 pmDetroit Metropolitan Wayne County
Apr 29
DTW7:18 amDetroit Metropolitan Wayne County
7h 05m
1 stop
ECP1:23 pmPanama City NW Florida Beaches
$379
United Airlines
Apr 25
ECP4:57 pmPanama City NW Florida Beaches
6h 01m
1 stop
DTW11:58 pmDetroit Metropolitan Wayne County
Apr 29
DTW7:18 amDetroit Metropolitan Wayne County
7h 05m
1 stop
ECP1:23 pmPanama City NW Florida Beaches
$397
United Airlines
Apr 14
ECP2:19 pmPanama City NW Florida Beaches
6h 58m
1 stop
DTW10:17 pmDetroit Metropolitan Wayne County
Apr 18
DTW6:00 amDetroit Metropolitan Wayne County
4h 48m
1 stop
ECP9:48 amPanama City NW Florida Beaches
$399

Southwest flights from Panama City, Florida to Detroit Metropolitan Wayne County Airport

Our best Southwest deals on Panama City, Florida to Detroit Metropolitan Wayne County Airport flight tickets
Southwest
Apr 25
ECP7:20 amPanama City NW Florida Beaches
6h 40m
1 stop
DTW3:00 pmDetroit Metropolitan Wayne County
May 2
DTW6:15 amDetroit Metropolitan Wayne County
3h 45m
1 stop
ECP9:00 amPanama City NW Florida Beaches
$335
Southwest
Apr 25
ECP7:20 amPanama City NW Florida Beaches
6h 40m
1 stop
DTW3:00 pmDetroit Metropolitan Wayne County
May 2
DTW6:15 amDetroit Metropolitan Wayne County
9h 15m
2 stops
ECP2:30 pmPanama City NW Florida Beaches
$340
Southwest
Apr 25
ECP12:40 pmPanama City NW Florida Beaches
9h 45m
2 stops
DTW11:25 pmDetroit Metropolitan Wayne County
May 2
DTW5:50 amDetroit Metropolitan Wayne County
8h 00m
2 stops
ECP12:50 pmPanama City NW Florida Beaches
$345

momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 3, 2026.
Use the filters below to find and compare flights from Panama City, Florida to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Thu 5/28

1:50 pm-6:55 pm

1 stop4h 05m

Detroit Metropolitan Wayne County

Sun 5/31

8:30 am-2:04 pm

1 stop6h 34m

$319

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Tue 6/23

4:16 pm-12:33 am

1 stop7h 17m

Detroit Metropolitan Wayne County

Tue 7/14

10:12 am-6:22 pm

2 stops9h 10m

$324

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Sat 4/25

7:20 am-3:00 pm

1 stop6h 40m

Detroit Metropolitan Wayne County

Sat 5/2

6:15 am-9:00 am

1 stop3h 45m

$335

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Sat 4/25

7:20 am-3:00 pm

1 stop6h 40m

Detroit Metropolitan Wayne County

Sat 5/2

6:15 am-2:30 pm

2 stops9h 15m

$340

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Sat 4/25

12:40 pm-11:25 pm

2 stops9h 45m

Detroit Metropolitan Wayne County

Sat 5/2

5:50 am-12:50 pm

2 stops8h 00m

$345

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Mon 5/4

4:40 pm-12:25 am

1 stop6h 45m

Detroit Metropolitan Wayne County

Fri 5/15

6:00 am-10:03 am

1 stop5h 03m

$349
Quickest round-trip

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Fri 4/24

5:49 am-11:02 am

1 stop4h 13m

Detroit Metropolitan Wayne County

Sun 5/3

5:20 am-8:35 am

1 stop4h 15m

$369

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Tue 4/28

4:57 pm-11:57 pm

1 stop6h 00m

Detroit Metropolitan Wayne County

Wed 4/29

7:18 am-1:23 pm

1 stop7h 05m

$379

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Mon 5/4

5:25 pm-10:20 pm

1 stop3h 55m

Detroit Metropolitan Wayne County

Fri 5/15

1:00 pm-6:20 pm

2 stops6h 20m

$384

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Wed 4/22

1:33 pm-6:39 pm

1 stop4h 06m

Detroit Metropolitan Wayne County

Tue 5/5

2:05 pm-6:00 pm

1 stop4h 55m

$389

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Detroit from

How to get the cheapest flight ticket from Panama City, Florida to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Panama City, Florida and Detroit Metropolitan Wayne County Airport?

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Panama City, Florida is in September. Flight prices, which tend to average around $258, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to Detroit Metropolitan Wayne County Airport from Panama City, Florida during April instead. Flights to Detroit Metropolitan Wayne County Airport in April, while not as cheap as those in September, still average around $292.

What is the cheapest Panama City NW Florida Beaches to Detroit Metropolitan Wayne County flight route?

Fly from Panama City NW Florida Beaches to Detroit Metropolitan Wayne County for the best Panama City NW Florida Beaches - Detroit Metropolitan Wayne County flight prices

What cabin class options are available on Panama City NW Florida Beaches to Detroit Metropolitan Wayne County flights?

There are 2 cabin classes available to choose from on Panama City NW Florida Beaches to Detroit Metropolitan Wayne County flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Panama City, Florida to Detroit Metropolitan Wayne County Airport flights?

You could potentially save up to 11% on your flight if you consider stops on a Panama City, Florida to Detroit Metropolitan Wayne County Airport flight.

How have Panama City, Florida to Detroit Metropolitan Wayne County Airport flight prices changed over time?

When to book flights from Panama City, Florida to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Detroit Metropolitan Wayne County Airport (ECP to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Detroit Metropolitan Wayne County Airport

Fastest flight time

3h 55m

Direct flights

Mon and Sun
The fastest flight from Panama City, Florida to Detroit Metropolitan Wayne County Airport takes 3h 55m
Direct flights go from Panama City, Florida to Detroit Metropolitan Wayne County Airport on Monday and Sunday. There are no airlines offering direct flights.
Search flight deals

Frequently asked questions about flying from Panama City, Florida to Detroit Metropolitan Wayne County Airport

  • How far is Panama City NW Florida Beaches to Detroit Metropolitan Wayne County by plane?

    The distance between Panama City NW Florida Beaches and Detroit Metropolitan Wayne County is about 842.6 mi. By plane, this route typically takes 3h 55m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Detroit Metropolitan Wayne County Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City NW Florida Beaches Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to Detroit Metropolitan Wayne County Airport?

Best airlines flying from Panama City, Florida to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Panama City, Florida to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $218Free CancellationRating
7.9
8,374 reviews
Search Delta flights
American AirlinesPriceFrom $238Free CancellationRating
7.1
11,551 reviews
Search American Airlines flights

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Dearborn
Romulus
Troy
Monroe
Southfield
Livonia
Novi
Port Clinton
Roseville
Port Huron
Sterling Heights
Dundee
Brighton
Ypsilanti
Pontiac
Farmington Hills
Plymouth

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Detroit?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to Detroit for you.

Can I find flights from Panama City to Detroit with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Detroit from Panama City with this policy.

How can momondo help me find flights from Panama City to Detroit?

Once you have performed a search for Panama City to Detroit flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Detroit right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Detroit flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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