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Cheap flights from Panama City, Florida to Detroit from $219

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Panama City, Florida to Detroit departing on 11/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Panama City, Florida to Detroit

Cheap round-trip flights

Southwest Logo
5:35 pm - 10:20 pmECP-DTW
3h 45m1 stop
Southwest Logo
5:25 pm - 9:05 pmDTW-ECP
4h 40m1 stop
$219Southwest
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Fri, Nov 7 - Mon, Nov 10
Southwest Logo
10:40 am - 9:30 pmECP-DTW
9h 50m1 stop
Southwest Logo
6:05 am - 9:00 amDTW-ECP
3h 55m1 stop
$224Southwest
Find Deal
Mon, Sep 22 - Thu, Sep 25
Delta Logo
6:00 am - 1:03 pmECP-DTW
6h 03m1 stop
Delta Logo
7:59 pm - 11:03 pmDTW-ECP
4h 04m1 stop
$238Delta
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Thu, Sep 11 - Tue, Sep 16
Delta Logo
6:00 am - 11:11 amECP-DTW
4h 11m1 stop
Delta Logo
7:59 pm - 11:03 pmDTW-ECP
4h 04m1 stop
$239Delta
Find Deal
Sun, Sep 7 - Mon, Sep 15
Delta Logo
5:00 pm - 12:56 amECP-DTW
6h 56m1 stop
Delta Logo
5:45 am - 10:19 amDTW-ECP
5h 34m1 stop
$243Delta
Find Deal
Fri, Oct 31 - Mon, Nov 3
Delta Logo
6:00 am - 11:09 amECP-DTW
4h 09m1 stop
Delta Logo
5:25 am - 8:08 amDTW-ECP
3h 43m1 stop
$259Delta
Find Deal
Mon, Sep 8 - Fri, Sep 19
American Airlines Logo
2:29 pm - 10:29 pmECP-DTW
7h 00m1 stop
American Airlines Logo
11:05 am - 5:36 pmDTW-ECP
7h 31m2 stops
$268American Airlines
Find Deal
Thu, Sep 11 - Wed, Sep 17
United Airlines Logo
6:30 am - 6:50 pmECP-DTW
11h 20m2 stops
United Airlines Logo
6:00 am - 1:03 pmDTW-ECP
8h 03m2 stops
$269United Airlines
Find Deal
Tue, Sep 9 - Sat, Sep 13
American Airlines Logo
12:01 pm - 11:21 pmECP-DTW
10h 20m2 stops
American Airlines Logo
11:05 am - 5:36 pmDTW-ECP
7h 31m2 stops
$273American Airlines
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Wed, Sep 10 - Wed, Sep 17
United Airlines Logo
5:06 pm - 11:56 pmECP-DTW
5h 50m1 stop
United Airlines Logo
7:00 am - 4:20 pmDTW-ECP
10h 20m2 stops
$314United Airlines
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Mon, Sep 8 - Sat, Sep 20

Delta flights from Panama City, Florida to Detroit Metropolitan Wayne County Airport

Our best Delta deals on Panama City, Florida to Detroit Metropolitan Wayne County Airport flight tickets
Delta
Sep 11
ECP6:00 amPanama City NW Florida Beaches
6h 03m
1 stop
DTW1:03 pmDetroit Metropolitan Wayne County
Sep 16
DTW7:59 pmDetroit Metropolitan Wayne County
4h 04m
1 stop
ECP11:03 pmPanama City NW Florida Beaches
$238
Find similar
Delta
Sep 7
ECP6:00 amPanama City NW Florida Beaches
4h 11m
1 stop
DTW11:11 amDetroit Metropolitan Wayne County
Sep 15
DTW7:59 pmDetroit Metropolitan Wayne County
4h 04m
1 stop
ECP11:03 pmPanama City NW Florida Beaches
$239
Find similar
Delta
Oct 31
ECP5:00 pmPanama City NW Florida Beaches
6h 56m
1 stop
DTW12:56 amDetroit Metropolitan Wayne County
Nov 3
DTW5:45 amDetroit Metropolitan Wayne County
5h 34m
1 stop
ECP10:19 amPanama City NW Florida Beaches
$243
Find similar

American Airlines flights from Panama City, Florida to Detroit Metropolitan Wayne County Airport

Our best American Airlines deals on Panama City, Florida to Detroit Metropolitan Wayne County Airport flight tickets
American Airlines
Aug 27
ECP12:06 pmPanama City NW Florida Beaches
6h 05m
1 stop
DTW7:11 pmDetroit Metropolitan Wayne County
Sep 5
DTW9:49 amDetroit Metropolitan Wayne County
5h 31m
1 stop
ECP2:20 pmPanama City NW Florida Beaches
$229
Find similar
American Airlines
Aug 27
ECP12:06 pmPanama City NW Florida Beaches
10h 33m
2 stops
DTW11:39 pmDetroit Metropolitan Wayne County
Sep 5
DTW9:49 amDetroit Metropolitan Wayne County
5h 31m
1 stop
ECP2:20 pmPanama City NW Florida Beaches
$234
Find similar
American Airlines
Sep 11
ECP2:29 pmPanama City NW Florida Beaches
7h 00m
1 stop
DTW10:29 pmDetroit Metropolitan Wayne County
Sep 17
DTW11:05 amDetroit Metropolitan Wayne County
7h 31m
2 stops
ECP5:36 pmPanama City NW Florida Beaches
$268
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momondo Fare Finder

 
Customize your flight search to find flights from Panama City, Florida to Detroit Metropolitan Wayne County Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 26, 2025.
Use the filters below to find and compare flights from Panama City, Florida to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Fri 11/7

5:35 pm-10:20 pm

1 stop3h 45m

Detroit Metropolitan Wayne County

Mon 11/10

5:25 pm-9:05 pm

1 stop4h 40m

$219

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Mon 9/22

10:40 am-9:30 pm

1 stop9h 50m

Detroit Metropolitan Wayne County

Thu 9/25

6:05 am-9:00 am

1 stop3h 55m

$224

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Thu 9/11

6:00 am-1:03 pm

1 stop6h 03m

Detroit Metropolitan Wayne County

Tue 9/16

7:59 pm-11:03 pm

1 stop4h 04m

$238

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Sun 9/7

6:00 am-11:11 am

1 stop4h 11m

Detroit Metropolitan Wayne County

Mon 9/15

7:59 pm-11:03 pm

1 stop4h 04m

$239

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Fri 10/31

5:00 pm-12:56 am

1 stop6h 56m

Detroit Metropolitan Wayne County

Mon 11/3

5:45 am-10:19 am

1 stop5h 34m

$243

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Mon 9/8

6:00 am-11:09 am

1 stop4h 09m

Detroit Metropolitan Wayne County

Fri 9/19

5:25 am-8:08 am

1 stop3h 43m

$259

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Thu 9/11

2:29 pm-10:29 pm

1 stop7h 00m

Detroit Metropolitan Wayne County

Wed 9/17

11:05 am-5:36 pm

2 stops7h 31m

$268

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Tue 9/9

6:30 am-6:50 pm

2 stops11h 20m

Detroit Metropolitan Wayne County

Sat 9/13

6:00 am-1:03 pm

2 stops8h 03m

$269

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Wed 9/10

12:01 pm-11:21 pm

2 stops10h 20m

Detroit Metropolitan Wayne County

Wed 9/17

11:05 am-5:36 pm

2 stops7h 31m

$273

Panama CityDetroit

ECP - DTW

ECPDTW

Panama City NW Florida Beaches

Mon 9/8

5:06 pm-11:56 pm

1 stop5h 50m

Detroit Metropolitan Wayne County

Sat 9/20

7:00 am-4:20 pm

2 stops10h 20m

$314

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Detroit from

How to get the cheapest flight ticket from Panama City, Florida to Detroit Metropolitan Wayne County Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Detroit Metropolitan Wayne County Airport?

The cheapest month to fly to Detroit Metropolitan Wayne County Airport from Panama City, Florida is in October. Flight prices, which tend to average around $286, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of October, then book flights to Detroit Metropolitan Wayne County Airport from Panama City, Florida during April instead. Flights to Detroit Metropolitan Wayne County Airport in April, while not as cheap as those in October, still average around $298.

What is the cheapest day to depart on your flight to Detroit Metropolitan Wayne County Airport?

The cheapest day to depart from Panama City, Florida to Detroit Metropolitan Wayne County Airport is on a Wednesday when prices can be found for as low as $284. Be sure to avoid booking your departure on a Friday as prices are generally higher than usual. According to our data, the average ticket price to Detroit Metropolitan Wayne County Airport on Friday is $791.

When to book flights from Panama City, Florida to Detroit Metropolitan Wayne County Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Panama City, Florida to Detroit Metropolitan Wayne County Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Panama City, Florida to Detroit Metropolitan Wayne County Airport (ECP to DTW) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Panama City, Florida to Detroit Metropolitan Wayne County Airport

Direct flights

None
There are no direct flights from Panama City, Florida to Detroit Metropolitan Wayne County Airport. There are no popular flight routes from Panama City, Florida to Detroit Metropolitan Wayne County Airport.
Search flight deals

  • How far is Panama City NW Florida Beaches to Detroit Metropolitan Wayne County by plane?

    The distance between Panama City NW Florida Beaches and Detroit Metropolitan Wayne County is about 842.6 mi. By plane, this route typically takes 3h 45m.

  • When did momondo last update prices for flights from Panama City NW Florida Beaches Airport to Detroit Metropolitan Wayne County Airport?

    Prices for flights from Panama City NW Florida Beaches Airport to Detroit Metropolitan Wayne County Airport are updated daily.

  • How many operators does momondo search for flights from Panama City NW Florida Beaches Airport to Detroit Metropolitan Wayne County Airport?

  • How old do you have to be to fly from Panama City NW Florida Beaches Airport to Detroit Metropolitan Wayne County Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Panama City NW Florida Beaches Airport to Detroit Metropolitan Wayne County Airport.

  • What documentation or ID do you need to fly to Detroit Metropolitan Wayne County Airport?

    The necessary travel and health documents for your Detroit Metropolitan Wayne County Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Panama City, Florida to Detroit Metropolitan Wayne County Airport?

Best airlines flying from Panama City, Florida to Detroit Metropolitan Wayne County Airport

Compare and see reviews for airlines that fly from Panama City, Florida to Detroit Metropolitan Wayne County Airport with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $218Free CancellationRating
7.9
7,979 reviews
Search Delta flights
American AirlinesPriceFrom $258Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

Traveling to a place near Detroit?

Book flights to Detroit if you plan to visit one of these locations
Put-in-Bay
Auburn Hills
Warren
Monroe
Southfield
Troy
Novi
Dearborn
Romulus
Livonia
Port Huron
Port Clinton
Sterling Heights
Roseville
Brighton
Ypsilanti
Pontiac
Madison Heights
Belleville
Royal Oak

Why use momondo?

Why should I use momondo to find a flight deal from Panama City to Detroit?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Panama City to Detroit for you.

Can I find flights from Panama City to Detroit with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Detroit from Panama City with this policy.

How can momondo help me find flights from Panama City to Detroit?

Once you have performed a search for Panama City to Detroit flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Panama City to Detroit right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Panama City to Detroit flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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