Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Chicago O'Hare Intl Airport to Panama City from $108

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Panama City departing on 11/11. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Chicago O'Hare Intl Airport to Panama City

Cheap round-trip flights

Copa Airlines Logo
2:07 pm - 8:35 pmORD-PTY
5h 28mnonstop
Copa Airlines Logo
7:50 am - 12:46 pmPTY-ORD
5h 56mnonstop
$451Copa Airlines
Find Deal
Sat, Nov 22 - Tue, Nov 25
Multiple Airlines Logo
10:20 pm - 4:55 pmORD-PTY
17h 35m1 stop
Multiple Airlines Logo
9:45 am - 12:30 pmPTY-ORD
27h 45m2 stops
$452Multiple Airlines
Find Deal
Thu, Jan 22 - Sun, Jan 25
Avianca Logo
4:10 pm - 10:30 amORD-PTY
17h 20m1 stop
Avianca Logo
9:45 am - 8:20 pmPTY-ORD
11h 35m1 stop
$453Avianca
Find Deal
Thu, Jan 8 - Thu, Jan 15
Multiple Airlines Logo
10:27 am - 7:29 pmORD-PTY
9h 02m1 stop
Multiple Airlines Logo
6:34 pm - 9:22 amPTY-ORD
14h 48m1 stop
$454Multiple Airlines
Find Deal
Sun, Oct 19 - Sun, Oct 26
Multiple Airlines Logo
2:35 pm - 12:10 amORD-PTY
9h 35m1 stop
Multiple Airlines Logo
9:34 am - 1:03 amPTY-ORD
15h 29m2 stops
$455Multiple Airlines
Find Deal
Thu, Oct 23 - Mon, Oct 27
Delta Logo
6:45 am - 7:59 pmORD-PTY
12h 14m1 stop
Delta Logo
8:05 am - 4:43 pmPTY-ORD
9h 38m1 stop
$465Delta
Find Deal
Sat, Dec 6 - Sat, Dec 13
Avianca Logo
4:10 pm - 8:50 amORD-PTY
15h 40m2 stops
Avianca Logo
9:45 am - 8:20 pmPTY-ORD
11h 35m1 stop
$468Avianca
Find Deal
Tue, Jan 27 - Tue, Feb 3
Delta Logo
7:59 pm - 12:56 pmORD-PTY
16h 57m1 stop
Delta Logo
2:21 pm - 9:43 amPTY-ORD
19h 22m2 stops
$470Delta
Find Deal
Thu, Oct 23 - Tue, Oct 28
American Airlines Logo
8:25 pm - 1:10 pmORD-PTY
15h 45m2 stops
American Airlines Logo
4:40 pm - 8:30 amPTY-ORD
16h 50m2 stops
$472American Airlines
Find Deal
Tue, Jan 27 - Fri, Feb 6
American Airlines Logo
5:00 am - 3:37 pmORD-PTY
9h 37m2 stops
American Airlines Logo
4:37 pm - 12:37 amPTY-ORD
9h 00m1 stop
$475American Airlines
Find Deal
Sat, Dec 6 - Sun, Dec 14

Avianca flights from Chicago O'Hare Intl Airport to Panama City

Our best Avianca deals on Chicago O'Hare Intl Airport to Panama City flight tickets
Avianca
Jan 8
ORD4:10 pmChicago O'Hare Intl
17h 20m
1 stop
PTY10:30 amPanama City Tocumen Intl
Jan 15
PTY9:45 amPanama City Tocumen Intl
11h 35m
1 stop
ORD8:20 pmChicago O'Hare Intl
$453
Find similar
Avianca
Oct 1
ORD10:54 amChicago O'Hare Intl
13h 51m
2 stops
PTY12:45 amPanama City Tocumen Intl
Oct 18
PTY10:05 pmPanama City Tocumen Intl
15h 10m
1 stop
ORD1:15 pmChicago O'Hare Intl
$461
Find similar
Avianca
Jan 27
ORD4:10 pmChicago O'Hare Intl
15h 40m
2 stops
PTY8:50 amPanama City Tocumen Intl
Feb 3
PTY9:45 amPanama City Tocumen Intl
11h 35m
1 stop
ORD8:20 pmChicago O'Hare Intl
$468
Find similar

American Airlines flights from Chicago O'Hare Intl Airport to Panama City

Our best American Airlines deals on Chicago O'Hare Intl Airport to Panama City flight tickets
American Airlines
Oct 1
ORD8:47 pmChicago O'Hare Intl
17h 44m
2 stops
PTY2:31 pmPanama City Tocumen Intl
Oct 18
PTY3:15 pmPanama City Tocumen Intl
17h 03m
2 stops
ORD8:18 amChicago O'Hare Intl
$470
Find similar
American Airlines
Jan 27
ORD8:25 pmChicago O'Hare Intl
15h 45m
2 stops
PTY1:10 pmPanama City Tocumen Intl
Feb 6
PTY4:40 pmPanama City Tocumen Intl
16h 50m
2 stops
ORD8:30 amChicago O'Hare Intl
$472
Find similar
American Airlines
Dec 6
ORD5:00 amChicago O'Hare Intl
9h 37m
2 stops
PTY3:37 pmPanama City Tocumen Intl
Dec 14
PTY4:37 pmPanama City Tocumen Intl
9h 00m
1 stop
ORD12:37 amChicago O'Hare Intl
$475
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 25, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 11/22

2:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Tue 11/25

7:50 am-12:46 pm

Nonstop5h 56m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/22

10:20 pm-4:55 pm

1 stop17h 35m

Panama City Tocumen Intl

Sun 1/25

9:45 am-12:30 pm

2 stops27h 45m

$452

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/8

4:10 pm-10:30 am

1 stop17h 20m

Panama City Tocumen Intl

Thu 1/15

9:45 am-8:20 pm

1 stop11h 35m

$453

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 10/19

10:27 am-7:29 pm

1 stop9h 02m

Panama City Tocumen Intl

Sun 10/26

6:34 pm-9:22 am

1 stop14h 48m

$454

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/23

2:35 pm-12:10 am

1 stop9h 35m

Panama City Tocumen Intl

Mon 10/27

9:34 am-1:03 am

2 stops15h 29m

$455

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 12/6

6:45 am-7:59 pm

1 stop12h 14m

Panama City Tocumen Intl

Sat 12/13

8:05 am-4:43 pm

1 stop9h 38m

$465

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Tue 1/27

4:10 pm-8:50 am

2 stops15h 40m

Panama City Tocumen Intl

Tue 2/3

9:45 am-8:20 pm

1 stop11h 35m

$468

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/23

7:59 pm-12:56 pm

1 stop16h 57m

Panama City Tocumen Intl

Tue 10/28

2:21 pm-9:43 am

2 stops19h 22m

$470

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Tue 1/27

8:25 pm-1:10 pm

2 stops15h 45m

Panama City Tocumen Intl

Fri 2/6

4:40 pm-8:30 am

2 stops16h 50m

$472

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 12/6

5:00 am-3:37 pm

2 stops9h 37m

Panama City Tocumen Intl

Sun 12/14

4:37 pm-12:37 am

1 stop9h 00m

$475

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Panama City from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, November is the cheapest month to fly from Chicago O'Hare Intl Airport to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $464. If you’re not able to fly to Panama City in November, then July is your next best option. Flight prices from Chicago O'Hare Intl Airport to Panama City during July average around $523.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $536. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $609. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Chicago O'Hare Intl Airport to Panama City during this time can be as low as $511. Try not to purchase tickets at noon because they tend to be around $606. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago O'Hare Intl to Panama City Tocumen Intl flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago O'Hare Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $583 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Chicago O'Hare Intl Airport for as low as $501 on momondo.

What cabin class options are available on Chicago O'Hare Intl to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Chicago O'Hare Intl to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Panama City flights?

You could potentially save up to 53% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Panama City flight.

How have Chicago O'Hare Intl Airport to Panama City flight prices changed over time?

As of September 2025, prices for Chicago O'Hare Intl Airport to Panama City flights are approximately 16% more expensive when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Panama City (ORD to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Panama City

Best Price Found

$162

Fastest flight time

5h 13m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Chicago O'Hare Intl Airport in the past 72 hours is $162. The best round-trip flight deal from Chicago O'Hare Intl Airport to Panama City found on momondo in the last 72 hours is $392.
The fastest flight from Chicago O'Hare Intl Airport to Panama City takes 5h 13m
Direct flights go from Chicago O'Hare Intl Airport to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • How far is Chicago O'Hare Intl to Panama City Tocumen Intl by plane?

    There are 2334.5 mi between Chicago O'Hare Intl and Panama City Tocumen Intl. In terms of flight time, this usually takes a little over 5h 22m.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Panama City?

  • What is the most popular airline from Chicago O'Hare Intl Airport to Panama City?

Best airlines flying from Chicago O'Hare Intl Airport to Panama City

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $334Free CancellationRating
6.7
2,442 reviews
Search Avianca flights
Copa AirlinesPriceFrom $464Free CancellationRating
7.6
1,539 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $479Free CancellationRating
7.4
8,926 reviews
Search United Airlines flights
DeltaPriceFrom $479Free CancellationRating
7.9
7,973 reviews
Search Delta flights
American AirlinesPriceFrom $563Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights

  • Copa Airlines Flights From Chicago O'Hare Intl Airport to Panama City

    Copa Airlines flies from Chicago O'Hare Intl Airport to Panama City around 10 times per week, with 1,539 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Chicago O'Hare Intl Airport to Panama City in the last 72 hours was $464 (round-trip), much lower than the average airfare cost of $578 for Copa Airlines flights on this route.

  • United Airlines Flights From Chicago O'Hare Intl Airport to Panama City

    United Airlines is also a popular choice for this route. United Airlines flight deals for Chicago O'Hare Intl Airport to Panama City start from as low as $479 round-trip, depending on your selected dates, with average United Airlines deals seen on momondo around $653. United Airlines operates 10 flights to Panama City from Chicago O'Hare Intl Airport in an average week. Users have rated it 7.4/10 across 8,926 reviews.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Chicago to Panama City for you.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Chicago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Chicago to Panama City?

Once you have performed a search for Chicago to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Panama City flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Panama City trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Sat 10/25
Sat 11/1
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Panama