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Cheap flights from Chicago O'Hare Intl Airport to Panama City from $100

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Panama City departing on 4/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago O'Hare Intl Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Avianca Logo
7:00 am - 1:55 am
ORD
-
PTY
18h 55m
3 stops
Avianca Logo
10:05 pm - 1:15 pm
PTY
-
ORD
15h 10m
1 stop
$556Avianca
Thu, Apr 9 - Sun, Apr 12
Multiple Airlines Logo
10:55 am - 7:20 pm
ORD
-
PTY
8h 25m
1 stop
Multiple Airlines Logo
5:25 pm - 8:25 am
PTY
-
ORD
15h 00m
2 stops
$560Multiple Airlines
Mon, Mar 16 - Mon, Mar 30
Multiple Airlines Logo
6:04 am - 12:40 am
ORD
-
PTY
17h 36m
2 stops
Multiple Airlines Logo
2:55 pm - 8:20 pm
PTY
-
ORD
30h 25m
1 stop
$561Multiple Airlines
Wed, Feb 25 - Sun, Mar 1
Multiple Airlines Logo
5:05 am - 8:34 pm
ORD
-
PTY
14h 29m
1 stop
Multiple Airlines Logo
9:45 am - 8:20 pm
PTY
-
ORD
11h 35m
1 stop
$564Multiple Airlines
Sat, Feb 28 - Wed, Mar 4
Avianca Logo
10:35 am - 12:45 am
ORD
-
PTY
14h 10m
2 stops
Avianca Logo
10:05 pm - 1:15 pm
PTY
-
ORD
15h 10m
1 stop
$567Avianca
Mon, Apr 6 - Thu, Apr 9
Multiple Airlines Logo
9:23 am - 1:00 am
ORD
-
PTY
14h 37m
2 stops
Multiple Airlines Logo
10:25 am - 6:16 pm
PTY
-
ORD
8h 51m
1 stop
$568Multiple Airlines
Tue, Feb 3 - Thu, Feb 5
Multiple Airlines Logo
10:55 am - 7:20 pm
ORD
-
PTY
8h 25m
1 stop
Multiple Airlines Logo
9:33 pm - 8:25 am
PTY
-
ORD
10h 52m
1 stop
$570Multiple Airlines
Wed, Mar 18 - Mon, Mar 30
Multiple Airlines Logo
11:20 pm - 8:50 am
ORD
-
PTY
9h 30m
1 stop
Multiple Airlines Logo
5:25 pm - 8:25 am
PTY
-
ORD
15h 00m
2 stops
$572Multiple Airlines
Sat, Mar 21 - Mon, Mar 30
Multiple Airlines Logo
11:20 pm - 8:50 am
ORD
-
PTY
9h 30m
1 stop
Multiple Airlines Logo
5:25 pm - 8:25 am
PTY
-
ORD
15h 00m
2 stops
$573Multiple Airlines
Thu, Mar 19 - Mon, Mar 30
Multiple Airlines Logo
10:55 am - 12:40 am
ORD
-
PTY
13h 45m
2 stops
Multiple Airlines Logo
6:34 pm - 8:25 am
PTY
-
ORD
13h 51m
1 stop
$574Multiple Airlines
Mon, Mar 16 - Wed, Apr 1

Copa Airlines flights from Chicago O'Hare Intl Airport to Panama City

Our best Copa Airlines deals on Chicago O'Hare Intl Airport to Panama City flight tickets
Copa Airlines
May 21
ORD8:02 amChicago O'Hare Intl
5h 20m
PTY1:22 pmPanama City Tocumen Intl
May 26
PTY7:25 pmPanama City Tocumen Intl
5h 50m
ORD1:15 amChicago O'Hare Intl
$584
Copa Airlines
Mar 18
ORD3:22 pmChicago O'Hare Intl
5h 13m
PTY8:35 pmPanama City Tocumen Intl
Mar 23
PTY7:20 pmPanama City Tocumen Intl
5h 44m
ORD1:04 amChicago O'Hare Intl
$593
Copa Airlines
Mar 14
ORD3:22 pmChicago O'Hare Intl
5h 13m
PTY8:35 pmPanama City Tocumen Intl
Mar 21
PTY7:20 pmPanama City Tocumen Intl
5h 44m
ORD1:04 amChicago O'Hare Intl
$602

Avianca flights from Chicago O'Hare Intl Airport to Panama City

Our best Avianca deals on Chicago O'Hare Intl Airport to Panama City flight tickets
Avianca
Feb 20
ORD10:20 pmChicago O'Hare Intl
9h 30m
1 stop
PTY8:50 amPanama City Tocumen Intl
Mar 2
PTY9:45 amPanama City Tocumen Intl
11h 35m
1 stop
ORD8:20 pmChicago O'Hare Intl
$487
Avianca
Feb 6
ORD7:16 amChicago O'Hare Intl
16h 24m
2 stops
PTY12:40 amPanama City Tocumen Intl
Feb 7
PTY2:55 amPanama City Tocumen Intl
18h 25m
1 stop
ORD8:20 pmChicago O'Hare Intl
$494
Avianca
Feb 16
ORD10:20 pmChicago O'Hare Intl
14h 40m
1 stop
PTY2:00 pmPanama City Tocumen Intl
Feb 24
PTY5:50 pmPanama City Tocumen Intl
18h 48m
2 stops
ORD11:38 amChicago O'Hare Intl
$500

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 4/9

7:00 am-1:55 am

3 stops18h 55m

Panama City Tocumen Intl

Sun 4/12

10:05 pm-1:15 pm

1 stop15h 10m

$556

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 3/16

10:55 am-7:20 pm

1 stop8h 25m

Panama City Tocumen Intl

Mon 3/30

5:25 pm-8:25 am

2 stops15h 00m

$560

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 2/25

6:04 am-12:40 am

2 stops17h 36m

Panama City Tocumen Intl

Sun 3/1

2:55 pm-8:20 pm

1 stop30h 25m

$561

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 2/28

5:05 am-8:34 pm

1 stop14h 29m

Panama City Tocumen Intl

Wed 3/4

9:45 am-8:20 pm

1 stop11h 35m

$564

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 4/6

10:35 am-12:45 am

2 stops14h 10m

Panama City Tocumen Intl

Thu 4/9

10:05 pm-1:15 pm

1 stop15h 10m

$567

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Tue 2/3

9:23 am-1:00 am

2 stops14h 37m

Panama City Tocumen Intl

Thu 2/5

10:25 am-6:16 pm

1 stop8h 51m

$568

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 3/18

10:55 am-7:20 pm

1 stop8h 25m

Panama City Tocumen Intl

Mon 3/30

9:33 pm-8:25 am

1 stop10h 52m

$570

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 3/21

11:20 pm-8:50 am

1 stop9h 30m

Panama City Tocumen Intl

Mon 3/30

5:25 pm-8:25 am

2 stops15h 00m

$572

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 3/19

11:20 pm-8:50 am

1 stop9h 30m

Panama City Tocumen Intl

Mon 3/30

5:25 pm-8:25 am

2 stops15h 00m

$573

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 3/16

10:55 am-12:40 am

2 stops13h 45m

Panama City Tocumen Intl

Wed 4/1

6:34 pm-8:25 am

1 stop13h 51m

$574

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, October is the cheapest month to fly from Chicago O'Hare Intl Airport to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $480. If you’re not able to fly to Panama City in October, then September is your next best option. Flight prices from Chicago O'Hare Intl Airport to Panama City during September average around $509.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $530. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $584. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Chicago O'Hare Intl Airport to Panama City during this time can be as low as $496. Try not to purchase tickets in the morning because they tend to be around $577. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago O'Hare Intl to Panama City Tocumen Intl flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago O'Hare Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $585 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Chicago O'Hare Intl Airport for as low as $535 on momondo.

What cabin class options are available on Chicago O'Hare Intl to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Chicago O'Hare Intl to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Panama City flights?

You could potentially save up to 81% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Panama City flight.

How have Chicago O'Hare Intl Airport to Panama City flight prices changed over time?

As of January 2026, prices for Chicago O'Hare Intl Airport to Panama City flights are approximately 35% more expensive when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Panama City (ORD to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Panama City

Best Price Found

$179

Fastest flight time

5h 13m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Chicago O'Hare Intl Airport in the past 72 hours is $179. The best round-trip flight deal from Chicago O'Hare Intl Airport to Panama City found on momondo in the last 72 hours is $376.
The fastest flight from Chicago O'Hare Intl Airport to Panama City takes 5h 13m
Direct flights go from Chicago O'Hare Intl Airport to Panama City every day.
There is 1 airport in Panama City. From Chicago O'Hare Intl Airport there are direct flights to Panama City Tocumen Intl (PTY).
Search flight deals

  • How far is Chicago O'Hare Intl to Panama City Tocumen Intl by plane?

    There are 2334.5 mi between Chicago O'Hare Intl and Panama City Tocumen Intl. In terms of flight time, this usually takes a little over 5h 13m.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Panama City?

  • What is the most popular airline from Chicago O'Hare Intl Airport to Panama City?

Best airlines flying from Chicago O'Hare Intl Airport to Panama City

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $272Free CancellationRating
6.6
2,496 reviews
Search Avianca flights
Copa AirlinesPriceFrom $463Free CancellationRating
7.6
1,559 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $479Free CancellationRating
7.4
9,188 reviews
Search United Airlines flights
DeltaPriceFrom $479Free CancellationRating
7.9
8,081 reviews
Search Delta flights
American AirlinesPriceFrom $563Free CancellationRating
7.2
11,169 reviews
Search American Airlines flights

  • Copa Airlines Flights From Chicago O'Hare Intl Airport to Panama City

    Copa Airlines flies from Chicago O'Hare Intl Airport to Panama City around 14 times per week, with 1,559 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Chicago O'Hare Intl Airport to Panama City in the last 72 hours was $463 (round-trip), much lower than the average airfare cost of $580 for Copa Airlines flights on this route.

  • United Airlines Flights From Chicago O'Hare Intl Airport to Panama City

    United Airlines is also a popular choice for this route. United Airlines flight deals for Chicago O'Hare Intl Airport to Panama City start from as low as $479 round-trip, depending on your selected dates, with average United Airlines deals seen on momondo around $653. United Airlines operates 12 flights to Panama City from Chicago O'Hare Intl Airport in an average week. Users have rated it 7.4/10 across 9,188 reviews.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Chicago to Panama City for you.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Chicago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Chicago to Panama City?

Once you have performed a search for Chicago to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Panama City flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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