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Cheap flights from Chicago O'Hare Intl Airport to Panama City from $179

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Panama City departing on 9/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago O'Hare Intl Airport to Panama City

Cheap round-trip flights

Logo
10:27 am - 7:29 pmORD-PTY
9h 02m1 stop
Logo
9:33 pm - 9:22 amPTY-ORD
11h 49m1 stop
$442
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Wed, Aug 27 - Mon, Sep 1
Logo
10:27 am - 7:29 pmORD-PTY
9h 02m1 stop
Logo
9:33 pm - 9:18 amPTY-ORD
11h 45m1 stop
$443
Find Deal
Tue, Sep 2 - Sun, Sep 7
Avianca Logo
2:35 pm - 12:45 amORD-PTY
10h 10m1 stop
Avianca Logo
3:25 am - 1:15 pmPTY-ORD
9h 50m1 stop
$446Avianca
Find Deal
Fri, Sep 12 - Mon, Sep 15
Copa Airlines Logo
3:07 pm - 8:35 pmORD-PTY
5h 28mnonstop
Copa Airlines Logo
6:45 pm - 12:21 amPTY-ORD
5h 36mnonstop
$451Copa Airlines
Find Deal
Fri, Sep 12 - Sun, Sep 21
Delta Logo
5:20 am - 12:56 pmORD-PTY
7h 36m1 stop
Delta Logo
2:21 pm - 8:32 amPTY-ORD
18h 11m1 stop
$465Delta
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Sat, Oct 11 - Mon, Oct 27
Copa Airlines Logo
7:53 am - 1:21 pmORD-PTY
5h 28mnonstop
Copa Airlines Logo
7:55 am - 1:41 pmPTY-ORD
5h 46mnonstop
$466Copa Airlines
Find Deal
Thu, Oct 2 - Sun, Oct 5
Delta Logo
7:59 pm - 12:56 pmORD-PTY
16h 57m1 stop
Delta Logo
2:21 pm - 9:12 amPTY-ORD
18h 51m2 stops
$470Delta
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Fri, Oct 17 - Fri, Oct 24
American Airlines Logo
8:29 pm - 2:31 pmORD-PTY
18h 02m2 stops
American Airlines Logo
3:31 pm - 7:42 amPTY-ORD
16h 11m2 stops
$471American Airlines
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Sat, Sep 20 - Sat, Sep 27
American Airlines Logo
7:05 am - 2:31 pmORD-PTY
7h 26m1 stop
American Airlines Logo
3:31 pm - 7:47 amPTY-ORD
16h 16m2 stops
$475American Airlines
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Fri, Sep 12 - Sun, Sep 21
Avianca Logo
2:35 pm - 12:45 amORD-PTY
10h 10m1 stop
Avianca Logo
3:20 am - 1:15 pmPTY-ORD
9h 55m1 stop
$476Avianca
Find Deal
Wed, Sep 3 - Sun, Sep 7

American Airlines flights from Chicago O'Hare Intl Airport to Panama City

Our best American Airlines deals on Chicago O'Hare Intl Airport to Panama City flight tickets
American Airlines
Sep 20
ORD8:29 pmChicago O'Hare Intl
18h 02m
2 stops
PTY2:31 pmPanama City Tocumen Intl
Sep 27
PTY3:31 pmPanama City Tocumen Intl
16h 11m
2 stops
ORD7:42 amChicago O'Hare Intl
$471
Find similar
American Airlines
Sep 12
ORD7:05 amChicago O'Hare Intl
7h 26m
1 stop
PTY2:31 pmPanama City Tocumen Intl
Sep 21
PTY3:31 pmPanama City Tocumen Intl
16h 16m
2 stops
ORD7:47 amChicago O'Hare Intl
$475
Find similar
American Airlines
Oct 1
ORD4:40 pmChicago O'Hare Intl
21h 51m
1 stop
PTY2:31 pmPanama City Tocumen Intl
Oct 8
PTY3:15 pmPanama City Tocumen Intl
8h 43m
1 stop
ORD11:58 pmChicago O'Hare Intl
$477
Find similar

Avianca flights from Chicago O'Hare Intl Airport to Panama City

Our best Avianca deals on Chicago O'Hare Intl Airport to Panama City flight tickets
Avianca
Sep 12
ORD2:35 pmChicago O'Hare Intl
10h 10m
1 stop
PTY12:45 amPanama City Tocumen Intl
Sep 15
PTY3:25 amPanama City Tocumen Intl
9h 50m
1 stop
ORD1:15 pmChicago O'Hare Intl
$446
Find similar
Avianca
Sep 3
ORD2:35 pmChicago O'Hare Intl
10h 10m
1 stop
PTY12:45 amPanama City Tocumen Intl
Sep 7
PTY3:20 amPanama City Tocumen Intl
9h 55m
1 stop
ORD1:15 pmChicago O'Hare Intl
$476
Find similar
Avianca
Sep 12
ORD2:35 pmChicago O'Hare Intl
10h 10m
1 stop
PTY12:45 amPanama City Tocumen Intl
Sep 18
PTY3:20 amPanama City Tocumen Intl
9h 55m
1 stop
ORD1:15 pmChicago O'Hare Intl
$481
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 8/27

10:27 am-7:29 pm

1 stop9h 02m

Panama City Tocumen Intl

Mon 9/1

9:33 pm-9:22 am

1 stop11h 49m

$442

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Tue 9/2

10:27 am-7:29 pm

1 stop9h 02m

Panama City Tocumen Intl

Sun 9/7

9:33 pm-9:18 am

1 stop11h 45m

$443

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 9/12

2:35 pm-12:45 am

1 stop10h 10m

Panama City Tocumen Intl

Mon 9/15

3:25 am-1:15 pm

1 stop9h 50m

$446

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 9/12

3:07 pm-8:35 pm

Nonstop5h 28m

Panama City Tocumen Intl

Sun 9/21

6:45 pm-12:21 am

Nonstop5h 36m

$451

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 10/11

5:20 am-12:56 pm

1 stop7h 36m

Panama City Tocumen Intl

Mon 10/27

2:21 pm-8:32 am

1 stop18h 11m

$465

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 10/2

7:53 am-1:21 pm

Nonstop5h 28m

Panama City Tocumen Intl

Sun 10/5

7:55 am-1:41 pm

Nonstop5h 46m

$466

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 10/17

7:59 pm-12:56 pm

1 stop16h 57m

Panama City Tocumen Intl

Fri 10/24

2:21 pm-9:12 am

2 stops18h 51m

$470

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 9/20

8:29 pm-2:31 pm

2 stops18h 02m

Panama City Tocumen Intl

Sat 9/27

3:31 pm-7:42 am

2 stops16h 11m

$471

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 9/12

7:05 am-2:31 pm

1 stop7h 26m

Panama City Tocumen Intl

Sun 9/21

3:31 pm-7:47 am

2 stops16h 16m

$475

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 9/3

2:35 pm-12:45 am

1 stop10h 10m

Panama City Tocumen Intl

Sun 9/7

3:20 am-1:15 pm

1 stop9h 55m

$476

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, September is the cheapest month to fly from Chicago O'Hare Intl Airport to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $479. If you’re not able to fly to Panama City in September, then November is your next best option. Flight prices from Chicago O'Hare Intl Airport to Panama City during November average around $479.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $534. If your travel schedule is flexible, try to avoid departing on a Saturday because tickets tend to average around $621. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Chicago O'Hare Intl Airport to Panama City during this time can be as low as $518. Try not to purchase tickets at noon because they tend to be around $599. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago O'Hare Intl to Panama City Tocumen Intl flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago O'Hare Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $577 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Chicago O'Hare Intl Airport for as low as $514 on momondo.

What cabin class options are available on Chicago O'Hare Intl to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Chicago O'Hare Intl to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Panama City flights?

You could potentially save up to 58% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Panama City flight.

How have Chicago O'Hare Intl Airport to Panama City flight prices changed over time?

As of August 2025, prices for Chicago O'Hare Intl Airport to Panama City flights are approximately 55% cheaper when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Panama City (ORD to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Panama City

Best Price Found

$179

Fastest flight time

5h 20m

Direct flights

Every day

Airports in Panama City

1 airport
The best one-way flight to Panama City from Chicago O'Hare Intl Airport in the past 72 hours is $179. The best round-trip flight deal from Chicago O'Hare Intl Airport to Panama City found on momondo in the last 72 hours is $442.
The fastest flight from Chicago O'Hare Intl Airport to Panama City takes 5h 20m
Direct flights go from Chicago O'Hare Intl Airport to Panama City every day.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
Search flight deals

  • How far is Chicago O'Hare Intl to Panama City Tocumen Intl by plane?

    There are 2334.5 mi between Chicago O'Hare Intl and Panama City Tocumen Intl. In terms of flight time, this usually takes a little over 5h 28m.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Panama City?

  • What is the most popular airline from Chicago O'Hare Intl Airport to Panama City?

Best airlines flying from Chicago O'Hare Intl Airport to Panama City

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $339Free CancellationRating
6.7
2,394 reviews
Search Avianca flights
Copa AirlinesPriceFrom $464Free CancellationRating
7.5
1,500 reviews
Search Copa Airlines flights
American AirlinesPriceFrom $478Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $478Free CancellationRating
8.0
7,985 reviews
Search Delta flights
United AirlinesPriceFrom $478Free CancellationRating
7.4
8,917 reviews
Search United Airlines flights

  • Copa Airlines Flights From Chicago O'Hare Intl Airport to Panama City

    Copa Airlines flies from Chicago O'Hare Intl Airport to Panama City around 13 times per week, with 1,500 momondo users rating the airline 7.5/10. The cheapest Copa Airlines deal from Chicago O'Hare Intl Airport to Panama City in the last 72 hours was $464 (round-trip), much lower than the average airfare cost of $586 for Copa Airlines flights on this route.

  • United Airlines Flights From Chicago O'Hare Intl Airport to Panama City

    United Airlines is also a popular choice for this route. United Airlines flight deals for Chicago O'Hare Intl Airport to Panama City start from as low as $478 round-trip, depending on your selected dates, with average United Airlines deals seen on momondo around $652. United Airlines operates 13 flights to Panama City from Chicago O'Hare Intl Airport in an average week. Users have rated it 7.4/10 across 8,917 reviews.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Chicago to Panama City for you.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Chicago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Chicago to Panama City?

Once you have performed a search for Chicago to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Panama City flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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