Cheap flights from Chicago O'Hare Intl Airport to Panama City from $160

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Panama City departing on 1/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Chicago O'Hare Intl Airport to Panama City

Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
9:14 am - 7:20 pmORD-PTY
9h 06m1 stop
Multiple Airlines Logo
9:33 pm - 8:09 amPTY-ORD
11h 36m1 stop
$466Multiple Airlines
Find Deal
Thu, Jan 15 - Mon, Jan 19
Multiple Airlines Logo
6:57 pm - 8:06 amORD-PTY
12h 09m1 stop
Multiple Airlines Logo
9:33 pm - 8:09 amPTY-ORD
11h 36m1 stop
$467Multiple Airlines
Find Deal
Sat, Jan 17 - Fri, Jan 23
Multiple Airlines Logo
9:14 am - 7:20 pmORD-PTY
9h 06m1 stop
Multiple Airlines Logo
5:50 pm - 8:09 amPTY-ORD
15h 19m2 stops
$468Multiple Airlines
Find Deal
Thu, Feb 5 - Mon, Feb 9
Multiple Airlines Logo
6:57 pm - 6:55 pmORD-PTY
22h 58m2 stops
Multiple Airlines Logo
2:55 pm - 8:09 amPTY-ORD
18h 14m2 stops
$469Multiple Airlines
Find Deal
Sat, Jan 10 - Sat, Jan 17
Multiple Airlines Logo
6:57 pm - 8:30 amORD-PTY
12h 33m1 stop
Multiple Airlines Logo
9:33 pm - 8:09 amPTY-ORD
11h 36m1 stop
$471Multiple Airlines
Find Deal
Fri, Jan 16 - Mon, Jan 19
Multiple Airlines Logo
6:57 pm - 8:06 amORD-PTY
12h 09m1 stop
Multiple Airlines Logo
9:33 pm - 8:09 amPTY-ORD
11h 36m1 stop
$472Multiple Airlines
Find Deal
Fri, Jan 16 - Sun, Jan 25
Multiple Airlines Logo
6:33 pm - 4:55 pmORD-PTY
21h 22m2 stops
Multiple Airlines Logo
5:50 pm - 10:43 pmPTY-ORD
29h 53m3 stops
$475Multiple Airlines
Find Deal
Mon, Feb 23 - Fri, Feb 27
Multiple Airlines Logo
6:57 pm - 8:06 amORD-PTY
12h 09m1 stop
Multiple Airlines Logo
9:33 pm - 9:16 amPTY-ORD
12h 43m1 stop
$477Multiple Airlines
Find Deal
Sun, Feb 8 - Sat, Feb 28
Multiple Airlines Logo
6:20 am - 8:50 amORD-PTY
25h 30m3 stops
Multiple Airlines Logo
9:45 am - 8:09 amPTY-ORD
23h 24m2 stops
$479Multiple Airlines
Find Deal
Wed, Jan 14 - Mon, Jan 19
Multiple Airlines Logo
6:57 pm - 8:06 amORD-PTY
12h 09m1 stop
Multiple Airlines Logo
8:10 am - 6:39 pmPTY-ORD
11h 29m1 stop
$480Multiple Airlines
Find Deal
Fri, Jan 16 - Sat, Jan 24

Avianca flights from Chicago O'Hare Intl Airport to Panama City

Our best Avianca deals on Chicago O'Hare Intl Airport to Panama City flight tickets
Avianca
Dec 1
ORD10:20 pmChicago O'Hare Intl
9h 30m
1 stop
PTY8:50 amPanama City Tocumen Intl
Dec 5
PTY2:55 amPanama City Tocumen Intl
18h 25m
1 stop
ORD8:20 pmChicago O'Hare Intl
Avianca
Dec 2
ORD8:45 amChicago O'Hare Intl
15h 15m
2 stops
PTY1:00 amPanama City Tocumen Intl
Dec 6
PTY9:45 amPanama City Tocumen Intl
11h 35m
1 stop
ORD8:20 pmChicago O'Hare Intl
Avianca
Dec 1
ORD10:20 pmChicago O'Hare Intl
14h 40m
1 stop
PTY2:00 pmPanama City Tocumen Intl
Dec 6
PTY9:45 amPanama City Tocumen Intl
11h 35m
1 stop
ORD8:20 pmChicago O'Hare Intl

Copa Airlines flights from Chicago O'Hare Intl Airport to Panama City

Our best Copa Airlines deals on Chicago O'Hare Intl Airport to Panama City flight tickets
Copa Airlines
Dec 1
ORD7:33 amChicago O'Hare Intl
5h 27m
PTY2:00 pmPanama City Tocumen Intl
Dec 8
PTY7:56 amPanama City Tocumen Intl
5h 56m
ORD12:52 pmChicago O'Hare Intl
Copa Airlines
Dec 5
ORD7:33 amChicago O'Hare Intl
5h 27m
PTY2:00 pmPanama City Tocumen Intl
Dec 13
PTY7:20 pmPanama City Tocumen Intl
5h 45m
ORD12:05 amChicago O'Hare Intl
Copa Airlines
Dec 1
ORD7:33 amChicago O'Hare Intl
5h 27m
PTY2:00 pmPanama City Tocumen Intl
Dec 6
PTY7:20 pmPanama City Tocumen Intl
5h 45m
ORD12:05 amChicago O'Hare Intl

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 1/15

9:14 am-7:20 pm

1 stop9h 06m

Panama City Tocumen Intl

Mon 1/19

9:33 pm-8:09 am

1 stop11h 36m

$466

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 1/17

6:57 pm-8:06 am

1 stop12h 09m

Panama City Tocumen Intl

Fri 1/23

9:33 pm-8:09 am

1 stop11h 36m

$467

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 2/5

9:14 am-7:20 pm

1 stop9h 06m

Panama City Tocumen Intl

Mon 2/9

5:50 pm-8:09 am

2 stops15h 19m

$468

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 1/10

6:57 pm-6:55 pm

2 stops22h 58m

Panama City Tocumen Intl

Sat 1/17

2:55 pm-8:09 am

2 stops18h 14m

$469

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 1/16

6:57 pm-8:30 am

1 stop12h 33m

Panama City Tocumen Intl

Mon 1/19

9:33 pm-8:09 am

1 stop11h 36m

$471

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 1/16

6:57 pm-8:06 am

1 stop12h 09m

Panama City Tocumen Intl

Sun 1/25

9:33 pm-8:09 am

1 stop11h 36m

$472

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Mon 2/23

6:33 pm-4:55 pm

2 stops21h 22m

Panama City Tocumen Intl

Fri 2/27

5:50 pm-10:43 pm

3 stops29h 53m

$475

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 2/8

6:57 pm-8:06 am

1 stop12h 09m

Panama City Tocumen Intl

Sat 2/28

9:33 pm-9:16 am

1 stop12h 43m

$477

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 1/14

6:20 am-8:50 am

3 stops25h 30m

Panama City Tocumen Intl

Mon 1/19

9:45 am-8:09 am

2 stops23h 24m

$479

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Fri 1/16

6:57 pm-8:06 am

1 stop12h 09m

Panama City Tocumen Intl

Sat 1/24

8:10 am-6:39 pm

1 stop11h 29m

$480

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama City from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Panama City

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama City?

In general, October is the cheapest month to fly from Chicago O'Hare Intl Airport to Panama City. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $480. If you’re not able to fly to Panama City in October, then September is your next best option. Flight prices from Chicago O'Hare Intl Airport to Panama City during September average around $521.

What is the cheapest day to depart on your flight to Panama City?

Our data shows that Tuesday is the least expensive day to fly to Panama City. Tickets to fly out on this day can be as low as $529. If your travel schedule is flexible, try to avoid departing on a Sunday because tickets tend to average around $594. These prices are subject to change though, so be sure to set up a Price Alert for flights to Panama City.

What is the cheapest time of day to depart on your flight to Panama City?

Our most recent data shows that the best time of day to fly to Panama City is in the evening. Flights from Chicago O'Hare Intl Airport to Panama City during this time can be as low as $502. Try not to purchase tickets in the morning because they tend to be around $581. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Chicago O'Hare Intl to Panama City Tocumen Intl flight route?

Fly from Chicago O'Hare Intl to Panama City Tocumen Intl for the best Chicago O'Hare Intl - Panama City Tocumen Intl flight prices

How far in advance should I book a flight to Panama City?

You are more likely to see cheaper flights to Panama City from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama City for around $567 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama City from Chicago O'Hare Intl Airport for as low as $528 on momondo.

What cabin class options are available on Chicago O'Hare Intl to Panama City Tocumen Intl flights?

There are 3 cabin classes available to choose from on Chicago O'Hare Intl to Panama City Tocumen Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Chicago O'Hare Intl Airport to Panama City flights?

You could potentially save up to 50% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Panama City flight.

How have Chicago O'Hare Intl Airport to Panama City flight prices changed over time?

As of November 2025, prices for Chicago O'Hare Intl Airport to Panama City flights are approximately 33% cheaper when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Panama City

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Panama City according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Panama City (ORD to PTY) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Panama City

Best Price Found

$214

Fastest flight time

5h 13m

Direct flights

Mon, Tue, Thu, Fri, Sat and Sun

Airports in Panama City

1 airport
The best one-way flight to Panama City from Chicago O'Hare Intl Airport in the past 72 hours is $214. The best round-trip flight deal from Chicago O'Hare Intl Airport to Panama City found on momondo in the last 72 hours is $464.
The fastest flight from Chicago O'Hare Intl Airport to Panama City takes 5h 13m
Direct flights go from Chicago O'Hare Intl Airport to Panama City on Monday, Tuesday, Thursday, Friday, Saturday and Sunday. There are no airlines offering direct flights.
There is 1 airport near Panama City: Panama City Tocumen Intl (PTY)
  • How far is Chicago O'Hare Intl to Panama City Tocumen Intl by plane?

    There are 2334.5 mi between Chicago O'Hare Intl and Panama City Tocumen Intl. In terms of flight time, this usually takes a little over 8h 49m.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport are updated daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Chicago O'Hare Intl Airport to Panama City Tocumen Intl Airport.

  • What documentation or ID do you need to fly to Panama City Tocumen Intl Airport?

    The travel and health documents you'll need for your trip to Panama City Tocumen Intl Airport may differ based on your itinerary and personal situation. Typically, you should have several documents on hand, such as a national ID card or driver's license and a passport that is valid for six months after your intended arrival at Panama City Tocumen Intl Airport. It is always advisable to seek advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Panama City?

  • What is the most popular airline from Chicago O'Hare Intl Airport to Panama City?

Best airlines flying from Chicago O'Hare Intl Airport to Panama City

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Panama City with momondo
Airline
Rating
Free Cancellation
Price
AviancaPriceFrom $356Free CancellationRating
6.6
2,477 reviews
Search Avianca flights
Copa AirlinesPriceFrom $464Free CancellationRating
7.6
1,569 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $479Free CancellationRating
7.4
9,046 reviews
Search United Airlines flights
DeltaPriceFrom $479Free CancellationRating
7.9
7,998 reviews
Search Delta flights
American AirlinesPriceFrom $589Free CancellationRating
7.2
11,038 reviews
Search American Airlines flights
  • Copa Airlines Flights From Chicago O'Hare Intl Airport to Panama City

    Copa Airlines flies from Chicago O'Hare Intl Airport to Panama City around 11 times per week, with 1,569 momondo users rating the airline 7.6/10. The cheapest Copa Airlines deal from Chicago O'Hare Intl Airport to Panama City in the last 72 hours was $464 (round-trip), much lower than the average airfare cost of $582 for Copa Airlines flights on this route.

  • United Airlines Flights From Chicago O'Hare Intl Airport to Panama City

    United Airlines is also a popular choice for this route. United Airlines flight deals for Chicago O'Hare Intl Airport to Panama City start from as low as $479 round-trip, depending on your selected dates, with average United Airlines deals seen on momondo around $653. United Airlines operates 11 flights to Panama City from Chicago O'Hare Intl Airport in an average week. Users have rated it 7.4/10 across 9,046 reviews.

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
San Blas

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Panama City?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Chicago to Panama City for you.

Can I find flights from Chicago to Panama City with flexible booking policies on momondo?

momondo does allow users to show only those flights to Panama City from Chicago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Chicago to Panama City?

Once you have performed a search for Chicago to Panama City flights, momondo helps you find the right one by offering useful filters to narrow down your flight selection. Flights can be filtered by multiple factors such as airline, airport and price; but also by other criteria like aircraft type and payment method.

I’m not ready to book a flight from Chicago to Panama City right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Chicago to Panama City flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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Fri 12/26
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