Cheap flights from Newark Airport to Santiago from $295

In general, May is the cheapest month to fly from Newark Airport to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $759. If you don’t want to visit Santiago in May, then you should wait until February to fly from Newark Airport, when ticket prices are also cheap, with an average price of $833.

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $899. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,028.

In the evening is the cheapest time of day to fly from Newark Airport to Santiago when you can find flight prices for as low as $907. Flying to Santiago in the evening is an ideal time because this is during off-peak travel hours. In the afternoon is when there is more demand to fly to Santiago, so prices are often more expensive at around $999 per ticket.

You are more likely to see cheaper flights to Santiago from Newark Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $879 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Newark Airport for as low as $698 on momondo.

You could potentially save up to 9% on your flight if you consider stops on a Newark Airport to Santiago flight.

As of October 2026, prices for Newark Airport to Santiago flights are approximately 36% cheaper when compared to flights at the same time last year.

Arajet is the most popular carrier operating from Newark to Santiago Arturo Merino Benitez

American Airlines, LATAM Airlines and United Airlines are the top three most popular airlines that fly to Santiago from Newark Airport according to our data. American Airlines is the first choice among our users, with 40% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 6 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Atlanta (ATL) was the most common stop: 50% of momondo users choosing 1-stop flights on this route connected there.

Flights via Punta Cana (PUJ) offer the lowest average round-trip price of $771.

Flights connecting via Miami (MIA) have the shortest average one-way travel time: 13h 36m.

Houston (IAH) has the shortest average layover time for this route: 2h 03m.