What airlines fly to Chicago O'Hare Intl Airport?

American Airlines, United Airlines and Contour are the top three most popular airlines that fly to Chicago O'Hare Intl Airport from Missouri according to our data. American Airlines is the first choice among our users, with 59% of people opting to fly with this airline when traveling to Chicago O'Hare Intl Airport. Keep in mind that there are 4 different airlines that fly to Chicago O'Hare Intl Airport on a routine basis, so you have a few additional options to choose from.

How many flights depart from Missouri to Chicago O'Hare Intl Airport on average per day?

As of July 2025, there are 116 flights per day flying from Missouri to Chicago O'Hare Intl Airport. The most common time of day flights depart is 8:00AM, with 53% of flights taking off at noon.

What is the cheapest airline that flies from Missouri to Chicago O'Hare Intl?

American Airlines, United Airlines, and Southwest are the most popular carriers operating from Missouri to Chicago O'Hare Intl

How long does it take to fly to Chicago O'Hare Intl Airport?

On average, it takes 1h 18m to fly from Missouri to Chicago O'Hare Intl Airport if you fly out of St. Louis (the most popular airport in Missouri) and into Chicago O'Hare Intl Airport (the most popular airport in Chicago O'Hare Intl Airport). If you’re flying out of Columbia and into Chicago O'Hare Intl Airport, then the flight time is around 1h 27m.

How many flights depart from Missouri to Chicago O'Hare Intl Airport on average per week?

813 flights are operational weekly from Missouri to Chicago O'Hare Intl Airport as of July 2025. The most popular departure day for this route is Thu, with 21% of flights per week taking off on this day.

When did momondo last update prices for flights from Missouri to Chicago O'Hare Intl Airport?

Prices for flights from Missouri to Chicago O'Hare Intl Airport were last updated today.

How many operators does momondo search for flights from Missouri to Chicago O'Hare Intl Airport?

As of July 2025, there are 4 operators available to choose from for flights from Missouri to Chicago O'Hare Intl Airport.

How old do you have to be to fly from Missouri to Chicago O'Hare Intl Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Chicago O'Hare Intl Airport.

What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

The travel and health documents required for your trip to Chicago O'Hare Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Chicago O'Hare Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$46 Cheap Flights from Missouri to Chicago O'Hare Intl Airport in 2025

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Find the cheapest flights from Missouri to Chicago

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

7:23 am - 8:45 amSTL-ORD

1h 22mnonstop

7:10 pm - 8:32 pmORD-STL

1h 22mnonstop

$91American Airlines

Find Deal

Sat, Sep 13 - Sat, Sep 20

4:50 pm - 11:05 pmSTL-ORD

6h 15m1 stop

11:25 am - 8:00 pmORD-STL

8h 35m1 stop

$111Southwest

Find Deal

Tue, Aug 26 - Wed, Aug 27

3:05 pm - 4:45 pmCGI-ORD

1h 40mnonstop

11:50 am - 1:25 pmORD-CGI

1h 35mnonstop

$122Contour

Find Deal

Tue, Sep 2 - Tue, Sep 9

9:10 am - 10:50 amCGI-ORD

1h 40mnonstop

5:30 pm - 7:05 pmORD-CGI

1h 35mnonstop

$140Contour

Find Deal

Wed, Aug 13 - Wed, Aug 20

5:30 pm - 6:55 pmSTL-ORD

1h 25mnonstop

2:20 pm - 3:44 pmORD-STL

1h 24mnonstop

$149United Airlines

Find Deal

Tue, Aug 26 - Wed, Aug 27

5:40 am - 7:37 amUIN-ORD

1h 57mnonstop

8:15 am - 10:10 amORD-UIN

1h 55mnonstop

$153Southern / Mokulele

Find Deal

Thu, Aug 14 - Mon, Aug 18

10:35 am - 12:32 pmUIN-ORD

1h 57mnonstop

8:15 am - 10:10 amORD-UIN

1h 55mnonstop

$158Southern / Mokulele

Find Deal

Wed, Aug 13 - Sun, Aug 17

1:26 pm - 7:05 pmSTL-ORD

5h 39m1 stop

5:30 am - 12:21 pmORD-STL

6h 51m1 stop

$177Delta

Find Deal

Sat, Sep 13 - Tue, Sep 16

3:20 pm - 4:45 pmSTL-ORD

1h 25mnonstop

12:55 pm - 2:19 pmORD-STL

1h 24mnonstop

$178United Airlines

Find Deal

Sat, Sep 6 - Mon, Sep 8

5:27 pm - 9:34 pmSTL-ORD

4h 07m1 stop

1:22 pm - 11:09 pmORD-STL

9h 47m2 stops

$182Delta

Find Deal

Sat, Sep 13 - Tue, Sep 16

Spirit Airlines flights from Missouri to Chicago O'Hare Intl Airport

Our best Spirit Airlines deals on Missouri to Chicago O'Hare Intl Airport flight tickets

Spirit Airlines

Aug 23

MCI6:00 amKansas City

10h 10m

1 stop

ORD4:10 pmChicago O'Hare Intl

Aug 25

ORD6:56 amChicago O'Hare Intl

15h 57m

1 stop

MCI10:53 pmKansas City

$211

Find similar

Spirit Airlines

Aug 27

MCI6:00 amKansas City

10h 10m

1 stop

ORD4:10 pmChicago O'Hare Intl

Sep 3

ORD6:56 amChicago O'Hare Intl

15h 57m

1 stop

MCI10:53 pmKansas City

$212

Find similar

Spirit Airlines

Aug 23

MCI6:00 amKansas City

16h 22m

1 stop

ORD10:22 pmChicago O'Hare Intl

Aug 25

ORD6:56 amChicago O'Hare Intl

15h 57m

1 stop

MCI10:53 pmKansas City

$213

Find similar

Southern / Mokulele flights from Missouri to Chicago O'Hare Intl Airport

Our best Southern / Mokulele deals on Missouri to Chicago O'Hare Intl Airport flight tickets

Southern / Mokulele

Aug 14

UIN5:40 amQuincy Regional

1h 57m

ORD7:37 amChicago O'Hare Intl

Aug 18

ORD8:15 amChicago O'Hare Intl

1h 55m

UIN10:10 amQuincy Regional

$153

Find similar

Southern / Mokulele

Aug 13

UIN10:35 amQuincy Regional

1h 57m

ORD12:32 pmChicago O'Hare Intl

Aug 17

ORD8:15 amChicago O'Hare Intl

1h 55m

UIN10:10 amQuincy Regional

$158

Find similar

Southern / Mokulele

Sep 12

STL1:00 pmLambert-St Louis

3h 19m

1 stop

ORD4:19 pmChicago O'Hare Intl

Sep 19

ORD8:15 amChicago O'Hare Intl

3h 45m

1 stop

STL12:00 pmLambert-St Louis

$166

Find similar

momondo Fare Finder

Use the filters below to find and compare flights from Missouri to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Sat 9/13

7:23 am-8:45 am

Nonstop1h 22m

Chicago O'Hare Intl

Sat 9/20

7:10 pm-8:32 pm

Nonstop1h 22m

$91

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Tue 8/26

4:50 pm-11:05 pm

1 stop6h 15m

Chicago O'Hare Intl

Wed 8/27

11:25 am-8:00 pm

1 stop8h 35m

$111

Cape GirardeauChicago

CGI - ORD

CGIORD

Cape Girardeau

Tue 9/2

3:05 pm-4:45 pm

Nonstop1h 40m

Chicago O'Hare Intl

Tue 9/9

11:50 am-1:25 pm

Nonstop1h 35m

$122

Cape GirardeauChicago

CGI - ORD

CGIORD

Cape Girardeau

Wed 8/13

9:10 am-10:50 am

Nonstop1h 40m

Chicago O'Hare Intl

Wed 8/20

5:30 pm-7:05 pm

Nonstop1h 35m

$140

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Tue 8/26

5:30 pm-6:55 pm

Nonstop1h 25m

Chicago O'Hare Intl

Wed 8/27

2:20 pm-3:44 pm

Nonstop1h 24m

$149

QuincyChicago

UIN - ORD

UINORD

Quincy Regional

Thu 8/14

5:40 am-7:37 am

Nonstop1h 57m

Chicago O'Hare Intl

Mon 8/18

8:15 am-10:10 am

Nonstop1h 55m

$153

QuincyChicago

UIN - ORD

UINORD

Quincy Regional

Wed 8/13

10:35 am-12:32 pm

Nonstop1h 57m

Chicago O'Hare Intl

Sun 8/17

8:15 am-10:10 am

Nonstop1h 55m

$158

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Sat 9/13

1:26 pm-7:05 pm

1 stop5h 39m

Chicago O'Hare Intl

Tue 9/16

5:30 am-12:21 pm

1 stop6h 51m

$177

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Sat 9/6

3:20 pm-4:45 pm

Nonstop1h 25m

Chicago O'Hare Intl

Mon 9/8

12:55 pm-2:19 pm

Nonstop1h 24m

$178

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Sat 9/13

5:27 pm-9:34 pm

1 stop4h 07m

Chicago O'Hare Intl

Tue 9/16

1:22 pm-11:09 pm

2 stops9h 47m

$182

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of September is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Missouri averaging around $203.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Thursday when prices can be found for as low as $791. This is often the case because there is less demand to fly during this day of the week. On the other hand, Monday is the most expensive day to depart from Missouri because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $975.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Missouri in the morning is the least expensive time of day to depart. momondo users have found prices as low as $663 when looking at flights departing in the morning. Try not to purchase tickets at noon because they tend to be around $1,272. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Missouri to Chicago O'Hare Intl flight route?

Fly from Kirksville Cannon Memorial to Chicago O'Hare Intl for the best Missouri - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $269 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Missouri for as low as $183 on momondo.

What cabin class options are available on Missouri to Chicago O'Hare Intl flights?

There are 4 cabin classes available to choose from on Missouri to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Cheap Missouri to Chicago O'Hare Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Chicago O'Hare Intl Airport

Best Price Found	$46
Fastest flight time	1h 20m
Direct flights	Every day

The best one-way flight to Chicago O'Hare Intl Airport from Missouri in the past 72 hours is $46. The best round-trip flight deal from Missouri to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $91.

The fastest flight from Missouri to Chicago O'Hare Intl Airport takes 1h 20m

Direct flights go from Missouri to Chicago O'Hare Intl Airport every day.

Search flight deals

When did momondo last update prices for flights from Missouri to Chicago O'Hare Intl Airport?
Prices for flights from Missouri to Chicago O'Hare Intl Airport were last updated today.
How many operators does momondo search for flights from Missouri to Chicago O'Hare Intl Airport?
As of July 2025, there are 4 operators available to choose from for flights from Missouri to Chicago O'Hare Intl Airport.
How old do you have to be to fly from Missouri to Chicago O'Hare Intl Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Chicago O'Hare Intl Airport.
What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?
The travel and health documents required for your trip to Chicago O'Hare Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Chicago O'Hare Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Missouri to Chicago O'Hare Intl Airport?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Missouri to Chicago O'Hare Intl Airport is Airbus A319 (13.07% of total bookings). The next most popular plane models are Boeing 737-800 (10.11%), Embraer 175 (9.47%), and Canadair (Bombardier) Regional Jet 700 (8.86%).

Best airlines flying from Missouri to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Missouri to Chicago O'Hare Intl Airport with momondo

Airline	Rating	Free Cancellation	Price
Contour	PriceFrom $86	Free Cancellation	Rating 7.1 32 reviews	Search Contour flights
American Airlines	PriceFrom $115	Free Cancellation	Rating 7.2 10,000 reviews	Search American Airlines flights
Southern / Mokulele	PriceFrom $129	Free Cancellation	Rating 6.4 26 reviews	Search Southern / Mokulele flights
United Airlines	PriceFrom $130	Free Cancellation	Rating 7.4 8,900 reviews	Search United Airlines flights

Lake Geneva

Rockford

Schaumburg

South Haven

Merrillville

Gurnee

Naperville

Rosemont

Kenosha

New Buffalo

Joliet

Oak Brook

Racine

Hammond

Tinley Park

Elgin

Orland Park

Aurora

Janesville

Benton Harbor

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Chicago?

It is quick and easy to find Missouri to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Missouri to Chicago with flexible booking policies on momondo?

Yes. All flights to Chicago from Missouri on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Missouri to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from Missouri. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Missouri to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Chicago O'Hare Intl Airport trip

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Cheap flights from Missouri to Chicago from $46

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Chicago departing on 11/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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Spirit Airlines flights from Missouri to Chicago O'Hare Intl Airport

Our best Spirit Airlines deals on Missouri to Chicago O'Hare Intl Airport flight tickets

Southern / Mokulele flights from Missouri to Chicago O'Hare Intl Airport

Our best Southern / Mokulele deals on Missouri to Chicago O'Hare Intl Airport flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Missouri to Chicago O'Hare Intl Airport that are best for you.

See travel insights to Chicago from

How to get the cheapest flight ticket from Missouri to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of September is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Missouri averaging around $203.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

What is the cheapest Missouri to Chicago O'Hare Intl flight route?

Fly from Kirksville Cannon Memorial to Chicago O'Hare Intl for the best Missouri - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

What cabin class options are available on Missouri to Chicago O'Hare Intl flights?

There are 4 cabin classes available to choose from on Missouri to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

What is the cheapest airline that flies from Missouri to Chicago O'Hare Intl?

American Airlines, United Airlines, and Southwest are the most popular carriers operating from Missouri to Chicago O'Hare Intl

What airlines fly to Chicago O'Hare Intl Airport?

How many flights depart from Missouri to Chicago O'Hare Intl Airport on average per day?

As of July 2025, there are 116 flights per day flying from Missouri to Chicago O'Hare Intl Airport. The most common time of day flights depart is 8:00AM, with 53% of flights taking off at noon.

How many flights depart from Missouri to Chicago O'Hare Intl Airport on average per week?

813 flights are operational weekly from Missouri to Chicago O'Hare Intl Airport as of July 2025. The most popular departure day for this route is Thu, with 21% of flights per week taking off on this day.

How long does it take to fly to Chicago O'Hare Intl Airport?

Cheap Missouri to Chicago O'Hare Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Chicago O'Hare Intl Airport

Best Price Found

Fastest flight time

Direct flights

When did momondo last update prices for flights from Missouri to Chicago O'Hare Intl Airport?

How many operators does momondo search for flights from Missouri to Chicago O'Hare Intl Airport?

How old do you have to be to fly from Missouri to Chicago O'Hare Intl Airport?

What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

What is the most popular plane model from Missouri to Chicago O'Hare Intl Airport?

Best airlines flying from Missouri to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Missouri to Chicago O'Hare Intl Airport with momondo

Traveling to a place near Chicago?

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Chicago?

Can I find flights from Missouri to Chicago with flexible booking policies on momondo?

How can momondo help me find flights from Missouri to Chicago?

I’m not ready to book a flight from Missouri to Chicago right now. Can momondo alert me if prices change?

An easier way to manage your Chicago O'Hare Intl Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Chicago

Popular cities in the United States

Popular flights according to clicks in the last 7 days on momondo