What airlines fly to Chicago O'Hare Intl Airport?

American Airlines, United Airlines and Contour are the top three most popular airlines that fly to Chicago O'Hare Intl Airport from Missouri according to our data. American Airlines is the first choice among our users, with 52% of people opting to fly with this airline when traveling to Chicago O'Hare Intl Airport. Keep in mind that there are 4 different airlines that fly to Chicago O'Hare Intl Airport on a routine basis, so you have a few additional options to choose from.

What is the cheapest airline that flies from Missouri to Chicago O'Hare Intl?

Contour, United Airlines, and Southwest are the most popular carriers operating from Missouri to Chicago O'Hare Intl

How long does it take to fly to Chicago O'Hare Intl Airport?

On average, it takes 1h 22m to fly from Missouri to Chicago O'Hare Intl Airport if you fly out of St. Louis (the most popular airport in Missouri) and into Chicago O'Hare Intl Airport (the most popular airport in Chicago O'Hare Intl Airport). If you’re flying out of Columbia and into Chicago O'Hare Intl Airport, then the flight time is around 1h 28m.

How many flights depart from Missouri to Chicago O'Hare Intl Airport on average per week?

888 flights are operational weekly from Missouri to Chicago O'Hare Intl Airport as of February 2026. The most popular departure day for this route is Fri, with 16% of flights per week taking off on this day.

How many flights depart from Missouri to Chicago O'Hare Intl Airport on average per day?

As of February 2026, there are 126 flights per day flying from Missouri to Chicago O'Hare Intl Airport. The most common time of day flights depart is 3:00PM, with 54% of flights taking off at noon.

When did momondo last update prices for flights from Missouri to Chicago O'Hare Intl Airport?

Prices for flights from Missouri to Chicago O'Hare Intl Airport were last updated today.

How many operators does momondo search for flights from Missouri to Chicago O'Hare Intl Airport?

As of February 2026, there are 4 operators available to choose from for flights from Missouri to Chicago O'Hare Intl Airport.

How old do you have to be to fly from Missouri to Chicago O'Hare Intl Airport?

The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Chicago O'Hare Intl Airport.

What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

The travel and health documents required for your trip to Chicago O'Hare Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Chicago O'Hare Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

$42 Cheap Flights from Missouri to Chicago O'Hare Intl Airport in 2026

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Find the cheapest flights from Missouri to Chicago

Round-trip

One-way

Last minute

Direct

Cheap round-trip flights

Enter your travel dates to find the best prices.

9:35 am - 11:10 am

UIN

ORD

1h 35mnonstop

12:05 pm - 1:25 pm

ORD

UIN

1h 20mnonstop

$83Contour

Sat, Mar 14 - Sat, Mar 21

9:50 am - 11:10 am

UIN

ORD

1h 20mnonstop

7:30 pm - 8:50 pm

ORD

UIN

1h 20mnonstop

$84Contour

Fri, Feb 20 - Sun, Feb 22

5:21 pm - 6:55 pm

STL

ORD

1h 34mnonstop

10:30 pm - 11:46 pm

ORD

STL

1h 16mnonstop

$112American Airlines

Wed, May 6 - Wed, May 6

3:49 pm - 3:52 pm

STL

ORD

24h 03m

1 stop

7:41 pm - 10:37 am

ORD

STL

14h 56m

1 stop

$118Frontier

Tue, Mar 3 - Tue, Mar 10

3:49 pm - 3:52 pm

STL

ORD

24h 03m

1 stop

9:28 am - 9:49 am

ORD

STL

24h 21m

2 stops

$139Frontier

Tue, Mar 3 - Tue, Mar 10

5:45 am - 11:10 am

STL

ORD

5h 25m

1 stop

2:40 pm - 10:00 pm

ORD

STL

7h 20m

1 stop

$142Southwest

Wed, May 6 - Wed, May 13

12:25 pm - 1:49 pm

STL

ORD

1h 24mnonstop

6:59 am - 8:24 am

ORD

STL

1h 25mnonstop

$144American Airlines

Wed, Apr 22 - Sat, Apr 25

5:45 am - 11:10 am

STL

ORD

5h 25m

1 stop

1:55 pm - 7:10 pm

ORD

STL

5h 15m

1 stop

$164Southwest

Wed, Apr 22 - Sat, Apr 25

7:45 am - 9:11 am

STL

ORD

1h 26mnonstop

9:30 pm - 10:56 pm

ORD

STL

1h 26mnonstop

$171United Airlines

Thu, Apr 9 - Thu, Apr 23

8:00 am - 9:30 am

COU

ORD

1h 30mnonstop

9:00 am - 10:33 am

ORD

COU

1h 33mnonstop

$179United Airlines

Thu, Mar 5 - Thu, Mar 12

United Airlines flights from Missouri to Chicago O'Hare Intl Airport

Our best United Airlines deals on Missouri to Chicago O'Hare Intl Airport flight tickets

United Airlines

Apr 9

STL7:45 amLambert-St Louis

1h 26m

ORD9:11 amChicago O'Hare Intl

Apr 23

ORD9:30 pmChicago O'Hare Intl

1h 26m

STL10:56 pmLambert-St Louis

$171

United Airlines

Mar 5

COU8:00 amColumbia Regional

1h 30m

ORD9:30 amChicago O'Hare Intl

Mar 12

ORD9:00 amChicago O'Hare Intl

1h 33m

COU10:33 amColumbia Regional

$179

United Airlines

May 15

COU11:30 amColumbia Regional

1h 30m

ORD1:00 pmChicago O'Hare Intl

May 16

ORD1:00 pmChicago O'Hare Intl

1h 32m

COU2:32 pmColumbia Regional

$194

American Airlines flights from Missouri to Chicago O'Hare Intl Airport

Our best American Airlines deals on Missouri to Chicago O'Hare Intl Airport flight tickets

American Airlines

May 6

STL5:21 pmLambert-St Louis

1h 34m

ORD6:55 pmChicago O'Hare Intl

May 6

ORD10:30 pmChicago O'Hare Intl

1h 16m

STL11:46 pmLambert-St Louis

$112

American Airlines

Apr 22

STL12:25 pmLambert-St Louis

1h 24m

ORD1:49 pmChicago O'Hare Intl

Apr 25

ORD6:59 amChicago O'Hare Intl

1h 25m

STL8:24 amLambert-St Louis

$144

American Airlines

Mar 4

SGF7:34 amSpringfield-Branson

1h 51m

ORD9:25 amChicago O'Hare Intl

Mar 11

ORD8:03 amChicago O'Hare Intl

1h 50m

SGF9:53 amSpringfield-Branson

$189

momondo Fare Finder

Use the filters below to find and compare flights from Missouri to Chicago O'Hare Intl Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

QuincyChicago

UIN - ORD

UINORD

Quincy Regional

Sat 3/14

9:35 am-11:10 am

Nonstop1h 35m

Chicago O'Hare Intl

Sat 3/21

12:05 pm-1:25 pm

Nonstop1h 20m

$83

QuincyChicago

UIN - ORD

UINORD

Quincy Regional

Fri 2/20

9:50 am-11:10 am

Nonstop1h 20m

Chicago O'Hare Intl

Sun 2/22

7:30 pm-8:50 pm

Nonstop1h 20m

$84

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Wed 5/6

5:21 pm-6:55 pm

Nonstop1h 34m

Chicago O'Hare Intl

Wed 5/6

10:30 pm-11:46 pm

Nonstop1h 16m

$112

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Tue 3/3

3:49 pm-3:52 pm

1 stop24h 03m

Chicago O'Hare Intl

Tue 3/10

7:41 pm-10:37 am

1 stop14h 56m

$118

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Tue 3/3

3:49 pm-3:52 pm

1 stop24h 03m

Chicago O'Hare Intl

Tue 3/10

9:28 am-9:49 am

2 stops24h 21m

$139

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Wed 5/6

5:45 am-11:10 am

1 stop5h 25m

Chicago O'Hare Intl

Wed 5/13

2:40 pm-10:00 pm

1 stop7h 20m

$142

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Wed 4/22

12:25 pm-1:49 pm

Nonstop1h 24m

Chicago O'Hare Intl

Sat 4/25

6:59 am-8:24 am

Nonstop1h 25m

$144

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Wed 4/22

5:45 am-11:10 am

1 stop5h 25m

Chicago O'Hare Intl

Sat 4/25

1:55 pm-7:10 pm

1 stop5h 15m

$164

St. LouisChicago

STL - ORD

STLORD

Lambert-St Louis

Thu 4/9

7:45 am-9:11 am

Nonstop1h 26m

Chicago O'Hare Intl

Thu 4/23

9:30 pm-10:56 pm

Nonstop1h 26m

$171

ColumbiaChicago

COU - ORD

COUORD

Columbia Regional

Thu 3/5

8:00 am-9:30 am

Nonstop1h 30m

Chicago O'Hare Intl

Thu 3/12

9:00 am-10:33 am

Nonstop1h 33m

$179

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first

How to get the cheapest flight ticket from Missouri to Chicago O'Hare Intl Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

Prices

Airlines

Other information

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of August is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Missouri averaging around $247.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Thursday when prices can be found for as low as $750. This is often the case because there is less demand to fly during this day of the week. On the other hand, Wednesday is the most expensive day to depart from Missouri because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $914.

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

Flying to Chicago O'Hare Intl Airport from Missouri in the morning is the least expensive time of day to depart. momondo users have found prices as low as $628 when looking at flights departing in the morning. Try not to purchase tickets at noon because they tend to be around $1,191. Of course, these prices can vary depending on the time of year and what airport you fly to.

What is the cheapest Missouri to Chicago O'Hare Intl flight route?

Fly from Kirksville Cannon Memorial to Chicago O'Hare Intl for the best Missouri - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Missouri when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $288 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Missouri for as low as $178 on momondo.

What cabin class options are available on Missouri to Chicago O'Hare Intl flights?

There are 4 cabin classes available to choose from on Missouri to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Missouri to Chicago O'Hare Intl Airport flights?

No. A direct flight is the cheapest option for a flight between Missouri to Chicago O'Hare Intl Airport.

Cheap Missouri to Chicago O'Hare Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Chicago O'Hare Intl Airport

Best Price Found	$69
Fastest flight time	1h 20m
Direct flights	Every day

The best one-way flight to Chicago O'Hare Intl Airport from Missouri in the past 72 hours is $69. The best round-trip flight deal from Missouri to Chicago O'Hare Intl Airport found on momondo in the last 72 hours is $158.

The fastest flight from Missouri to Chicago O'Hare Intl Airport takes 1h 20m

Direct flights go from Missouri to Chicago O'Hare Intl Airport every day.

Search flight deals

When did momondo last update prices for flights from Missouri to Chicago O'Hare Intl Airport?
Prices for flights from Missouri to Chicago O'Hare Intl Airport were last updated today.
How many operators does momondo search for flights from Missouri to Chicago O'Hare Intl Airport?
As of February 2026, there are 4 operators available to choose from for flights from Missouri to Chicago O'Hare Intl Airport.
How old do you have to be to fly from Missouri to Chicago O'Hare Intl Airport?
The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Missouri to Chicago O'Hare Intl Airport.
What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?
The travel and health documents required for your trip to Chicago O'Hare Intl Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Chicago O'Hare Intl Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.
What is the most popular plane model from Missouri to Chicago O'Hare Intl Airport?
Based on momondo bookings for this flight route, the most popular plane model on flight routes from Missouri to Chicago O'Hare Intl Airport is Embraer 170 (14.68% of total bookings). The next most popular plane models are Embraer 175 (10.26%), Canadair (Bombardier) Regional Jet CRJ-550 (9.83%), and Boeing 737-800 (9.28%).

Best airlines flying from Missouri to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Missouri to Chicago O'Hare Intl Airport with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $107	Free Cancellation	Rating 7.2 11,245 reviews	Search American Airlines flights
United Airlines	PriceFrom $114	Free Cancellation	Rating 7.4 9,246 reviews	Search United Airlines flights
Contour	PriceFrom $123	Free Cancellation	Rating 7.6 42 reviews	Search Contour flights
Southern / Mokulele	PriceFrom $140	Free Cancellation	Rating 0.0 0 reviews	Search Southern / Mokulele flights

Lake Geneva

Schaumburg

South Haven

Rockford

Merrillville

Gurnee

Naperville

Rosemont

New Buffalo

Kenosha

Joliet

Oak Brook

Orland Park

Racine

Hammond

Janesville

Tinley Park

Elgin

Aurora

South Holland

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Chicago?

It is quick and easy to find Missouri to Chicago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Chicago that suits you.

Can I find flights from Missouri to Chicago with flexible booking policies on momondo?

Yes. All flights to Chicago from Missouri on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Missouri to Chicago?

momondo provides multiple filters to help you find the best flight to Chicago from Missouri. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Missouri to Chicago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Missouri to Chicago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

An easier way to manage your Chicago O'Hare Intl Airport trip

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Cheap flights from Missouri to Chicago from $42

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Missouri to Chicago departing on 6/2. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.

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United Airlines flights from Missouri to Chicago O'Hare Intl Airport

Our best United Airlines deals on Missouri to Chicago O'Hare Intl Airport flight tickets

American Airlines flights from Missouri to Chicago O'Hare Intl Airport

Our best American Airlines deals on Missouri to Chicago O'Hare Intl Airport flight tickets

momondo Fare Finder

Use the filters below to find and compare flights from Missouri to Chicago O'Hare Intl Airport that are best for you.

See travel insights to Chicago from

How to get the cheapest flight ticket from Missouri to Chicago O'Hare Intl Airport

What is the cheapest month to fly to Chicago O'Hare Intl Airport?

The month of August is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Missouri averaging around $247.

What is the cheapest day to depart on your flight to Chicago O'Hare Intl Airport?

What is the cheapest time of day to depart on your flight to Chicago O'Hare Intl Airport?

What is the cheapest Missouri to Chicago O'Hare Intl flight route?

Fly from Kirksville Cannon Memorial to Chicago O'Hare Intl for the best Missouri - Chicago O'Hare Intl flight prices

How far in advance should I book a flight to Chicago O'Hare Intl Airport?

What cabin class options are available on Missouri to Chicago O'Hare Intl flights?

There are 4 cabin classes available to choose from on Missouri to Chicago O'Hare Intl flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Missouri to Chicago O'Hare Intl Airport flights?

No. A direct flight is the cheapest option for a flight between Missouri to Chicago O'Hare Intl Airport.

What is the cheapest airline that flies from Missouri to Chicago O'Hare Intl?

Contour, United Airlines, and Southwest are the most popular carriers operating from Missouri to Chicago O'Hare Intl

What airlines fly to Chicago O'Hare Intl Airport?

How many flights depart from Missouri to Chicago O'Hare Intl Airport on average per day?

As of February 2026, there are 126 flights per day flying from Missouri to Chicago O'Hare Intl Airport. The most common time of day flights depart is 3:00PM, with 54% of flights taking off at noon.

How many flights depart from Missouri to Chicago O'Hare Intl Airport on average per week?

888 flights are operational weekly from Missouri to Chicago O'Hare Intl Airport as of February 2026. The most popular departure day for this route is Fri, with 16% of flights per week taking off on this day.

How long does it take to fly to Chicago O'Hare Intl Airport?

Cheap Missouri to Chicago O'Hare Intl Airport flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Missouri to Chicago O'Hare Intl Airport

Best Price Found

Fastest flight time

Direct flights

When did momondo last update prices for flights from Missouri to Chicago O'Hare Intl Airport?

How many operators does momondo search for flights from Missouri to Chicago O'Hare Intl Airport?

How old do you have to be to fly from Missouri to Chicago O'Hare Intl Airport?

What documentation or ID do you need to fly to Chicago O'Hare Intl Airport?

What is the most popular plane model from Missouri to Chicago O'Hare Intl Airport?

Best airlines flying from Missouri to Chicago O'Hare Intl Airport

Compare and see reviews for airlines that fly from Missouri to Chicago O'Hare Intl Airport with momondo

Traveling to a place near Chicago?

Why use momondo?

Why should I use momondo to find a flight deal from Missouri to Chicago?

Can I find flights from Missouri to Chicago with flexible booking policies on momondo?

How can momondo help me find flights from Missouri to Chicago?

I’m not ready to book a flight from Missouri to Chicago right now. Can momondo alert me if prices change?

An easier way to manage your Chicago O'Hare Intl Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.

Find better results for your trip to Chicago

Popular cities in the United States

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According to popular flight searches on momondo this year

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List of cabin classes available on flights landing in Chicago. Availability may vary depending on flight origin and airline.

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