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Cheap flights from Chicago Midway Airport to Brussels from $345

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago Midway Airport to Brussels departing on 4/23. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Chicago Midway Airport to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
Delta Logo
9:22 am - 9:40 am
MDW
-
BRU
17h 18m
2 stops
Delta Logo
9:45 am - 4:12 pm
BRU
-
MDW
13h 27m
1 stop
$994Delta
Thu, May 7 - Thu, May 14
Delta Logo
9:22 am - 7:35 am
MDW
-
BRU
15h 13m
2 stops
Delta Logo
9:45 am - 6:33 pm
BRU
-
MDW
15h 48m
2 stops
$999Delta
Thu, May 7 - Thu, May 14
Multiple Airlines Logo
9:22 am - 7:35 am
MDW
-
BRU
15h 13m
2 stops
Multiple Airlines Logo
9:45 am - 9:09 pm
BRU
-
MDW
18h 24m
1 stop
$1,025Multiple Airlines
Thu, May 7 - Thu, May 14
Multiple Airlines Logo
9:22 am - 7:35 am
MDW
-
BRU
15h 13m
2 stops
Multiple Airlines Logo
9:45 am - 6:33 pm
BRU
-
MDW
15h 48m
2 stops
$1,030Multiple Airlines
Thu, May 7 - Thu, May 14
Delta Logo
9:22 am - 9:40 am
MDW
-
BRU
17h 18m
2 stops
Delta Logo
9:45 am - 4:12 pm
BRU
-
MDW
13h 27m
1 stop
$1,044Delta
Thu, May 7 - Thu, May 14
Delta Logo
9:22 am - 7:35 am
MDW
-
BRU
15h 13m
2 stops
Delta Logo
9:45 am - 6:33 pm
BRU
-
MDW
15h 48m
2 stops
$1,049Delta
Thu, May 7 - Thu, May 14
Delta Logo
6:23 am - 7:40 am
MDW
-
BRU
18h 17m
1 stop
Delta Logo
9:45 am - 4:12 pm
BRU
-
MDW
13h 27m
1 stop
$1,081Delta
Sun, May 10 - Tue, May 19
Delta Logo
6:23 am - 7:40 am
MDW
-
BRU
18h 17m
1 stop
Delta Logo
9:45 am - 6:33 pm
BRU
-
MDW
15h 48m
2 stops
$1,086Delta
Sun, May 10 - Tue, May 19
KLM Logo
6:23 am - 7:40 am
MDW
-
BRU
18h 17m
1 stop
KLM Logo
9:45 am - 4:12 pm
BRU
-
MDW
13h 27m
1 stop
$1,117KLM
Sun, May 10 - Tue, May 19
Delta Logo
9:22 am - 9:40 am
MDW
-
BRU
17h 18m
2 stops
Delta Logo
9:45 am - 4:12 pm
BRU
-
MDW
13h 27m
1 stop
$1,119Delta
Thu, May 7 - Thu, May 14

KLM flights from Chicago Midway Airport to Brussels

Our best KLM deals on Chicago Midway Airport to Brussels flight tickets
KLM
May 10
MDW6:23 amChicago Midway
18h 17m
1 stop
BRU7:40 amBrussels Bruxelles-National
May 19
BRU9:45 amBrussels Bruxelles-National
13h 27m
1 stop
MDW4:12 pmChicago Midway
$1,117
KLM
May 10
MDW6:23 amChicago Midway
18h 17m
1 stop
BRU7:40 amBrussels Bruxelles-National
May 19
BRU10:25 amBrussels Bruxelles-National
14h 31m
2 stops
MDW5:56 pmChicago Midway
$1,126
KLM
May 10
MDW6:36 pmChicago Midway
13h 04m
2 stops
BRU2:40 pmBrussels Bruxelles-National
May 19
BRU10:25 amBrussels Bruxelles-National
14h 31m
2 stops
MDW5:56 pmChicago Midway
$1,135

Air France flights from Chicago Midway Airport to Brussels

Our best Air France deals on Chicago Midway Airport to Brussels flight tickets
Air France
Apr 20
MDW12:52 pmChicago Midway
11h 48m
1 stop
BRU7:40 amBrussels Bruxelles-National
Apr 28
BRU9:45 amBrussels Bruxelles-National
13h 41m
1 stop
MDW4:26 pmChicago Midway
$1,183
Air France
Sep 13
MDW1:05 pmChicago Midway
11h 35m
1 stop
BRU7:40 amBrussels Bruxelles-National
Sep 24
BRU9:45 amBrussels Bruxelles-National
13h 42m
1 stop
MDW4:27 pmChicago Midway
$1,226
Air France
Apr 22
MDW12:52 pmChicago Midway
11h 48m
1 stop
BRU7:40 amBrussels Bruxelles-National
May 4
BRU9:45 amBrussels Bruxelles-National
13h 41m
1 stop
MDW4:26 pmChicago Midway
$1,233

momondo Fare Finder

 
Customize your flight search to find flights from Chicago Midway Airport to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated March 21, 2026.
Use the filters below to find and compare flights from Chicago Midway Airport to Brussels that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 5/7

9:22 am-9:40 am

2 stops17h 18m

Brussels Bruxelles-National

Thu 5/14

9:45 am-4:12 pm

1 stop13h 27m

$994

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 5/7

9:22 am-7:35 am

2 stops15h 13m

Brussels Bruxelles-National

Thu 5/14

9:45 am-6:33 pm

2 stops15h 48m

$999

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 5/7

9:22 am-7:35 am

2 stops15h 13m

Brussels Bruxelles-National

Thu 5/14

9:45 am-9:09 pm

1 stop18h 24m

$1,025

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 5/7

9:22 am-7:35 am

2 stops15h 13m

Brussels Bruxelles-National

Thu 5/14

9:45 am-6:33 pm

2 stops15h 48m

$1,030

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 5/7

9:22 am-9:40 am

2 stops17h 18m

Brussels Bruxelles-National

Thu 5/14

9:45 am-4:12 pm

1 stop13h 27m

$1,044

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 5/7

9:22 am-7:35 am

2 stops15h 13m

Brussels Bruxelles-National

Thu 5/14

9:45 am-6:33 pm

2 stops15h 48m

$1,049

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Sun 5/10

6:23 am-7:40 am

1 stop18h 17m

Brussels Bruxelles-National

Tue 5/19

9:45 am-4:12 pm

1 stop13h 27m

$1,081

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Sun 5/10

6:23 am-7:40 am

1 stop18h 17m

Brussels Bruxelles-National

Tue 5/19

9:45 am-6:33 pm

2 stops15h 48m

$1,086

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Sun 5/10

6:23 am-7:40 am

1 stop18h 17m

Brussels Bruxelles-National

Tue 5/19

9:45 am-4:12 pm

1 stop13h 27m

$1,117

ChicagoBrussels

MDW - BRU

MDWBRU

Chicago Midway

Thu 5/7

9:22 am-9:40 am

2 stops17h 18m

Brussels Bruxelles-National

Thu 5/14

9:45 am-4:12 pm

1 stop13h 27m

$1,119

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Brussels from

How to get the cheapest flight ticket from Chicago Midway Airport to Brussels

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Brussels?

On average, the least expensive day to fly to Brussels from Chicago Midway Airport is on a Tuesday. momondo users have found tickets for Tuesday departures for as low as $1,058. However, this price may fluctuate depending on the airline, the season, and holidays. On the other hand, Saturday is the most expensive day to depart from Chicago Midway Airport because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $1,304.

Cheap Chicago Midway Airport to Brussels flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago Midway Airport to Brussels

Fastest flight time

13h 25m

Direct flights

None
The fastest flight from Chicago Midway Airport to Brussels takes 13h 25m
There are no direct flights from Chicago Midway Airport to Brussels. There are no popular flight routes from Chicago Midway Airport to Brussels.
Search flight deals

  • How far is Chicago Midway to Brussels by plane?

    Chicago Midway and Brussels are 4144.7 mi apart from one another. 13h 25m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Chicago Midway Airport to Brussels?

    Prices for flights from Chicago Midway Airport to Brussels were last updated today.

  • How old do you have to be to fly from Chicago Midway Airport to Brussels?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Chicago Midway Airport to Brussels.

  • What documentation or ID do you need to fly to Brussels?

    The required travel and health documents for your Brussels trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Brussels. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Brussels?

It is quick and easy to find Chicago to Brussels flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Brussels that suits you.

Can I find flights from Chicago to Brussels with flexible booking policies on momondo?

momondo does allow users to show only those flights to Brussels from Chicago which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Chicago to Brussels?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Brussels from Chicago.

I’m not ready to book a flight from Chicago to Brussels right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Brussels, momondo offers a useful price alert feature which will track prices for flights to Brussels from Chicago and alert you when they change.

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Find better results for your trip to Belgium

Fly into one of these airports located in Brussels

Airports listed have a maximum distance of 27.4 mi from Brussels
Brussels Bruxelles-National Airport
Charleroi Brussels Airport