Cheap flights from Mexico City to Cali from $159

The cheapest month to fly to Cali from Mexico City is in February. Flight prices, which tend to average around $273, are often lower during this time because this is during the off-season. If you’re not able to fly to Cali in February, then October is your next best option. Flight prices from Mexico City to Cali during October average around $277.

The cheapest day to depart on your flight to Cali is on a Tuesday when prices can be found for as low as $278. This is often the case because there is less demand to fly during this day of the week. If your travel schedule is flexible, try to avoid departing on a Thursday because tickets tend to average around $506. These prices are subject to change though, so be sure to set up a Price Alert for flights to Cali.

Our most recent data shows that the best time of day to fly to Cali is in the morning. Flights from Mexico City to Cali during this time can be as low as $278. At noon is when there is more demand to fly to Cali, so prices are often more expensive at around $360 per ticket.

Fly from Mexico City Benito Juarez to Cali Alfonso B. Aragon Intl for the best Mexico City Benito Juarez - Cali Alfonso B. Aragon Intl flight prices

You are more likely to see cheaper flights to Cali from Mexico City when booking weeks ahead of your departure date. In general, you can expect to find flights to Cali for around $321 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Cali from Mexico City for as low as $270 on momondo.

You could potentially save up to 57% on your flight if you consider stops on a Mexico City to Cali flight.

As of April 2026, prices for Mexico City to Cali flights are approximately 14% cheaper when compared to flights at the same time last year.

Historically, on average around 5% of flights between Mexico City and Cali have experienced a delay on any given week. The average delay length over the past 12 months has been 100 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the early afternoon have, in the past, seen delays more frequently in comparison.

Thursday is statistically the day of the week which experiences the fewest number of delays on this flight route. Tuesday has historically seen more delays on average compared to the rest of the week.

According to our data, Aeromexico have had the least number of delays on this route over the last 12 months; with about 5% of their flights experiencing any sort of delay.