Cheap flights from Mendoza to Santiago from $66

In general, October is the cheapest month to fly from Mendoza to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $124. If you don’t want to visit Santiago in October, then you should wait until May to fly from Mendoza, when ticket prices are also cheap, with an average price of $126.

The cheapest day to depart on your flight to Santiago is on a Saturday when prices can be found for as low as $401. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Sunday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Sunday is $912.

In the afternoon is the cheapest time of day to fly from Mendoza to Santiago when you can find flight prices for as low as $142. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. At noon is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,006 per ticket.

Fly from Mendoza El Plumerillo to Santiago Arturo Merino Benitez for the best Mendoza El Plumerillo - Santiago Arturo Merino Benitez flight prices

You are more likely to see cheaper flights to Santiago from Mendoza when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $137 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Mendoza for as low as $120 on momondo.

JetSMART and Sky Airline are the most popular carriers operating from Mendoza El Plumerillo to Santiago Arturo Merino Benitez

Sky Airline, LATAM Airlines and JetSMART are the top three most popular airlines that fly to Santiago from Mendoza according to our data. Sky Airline is the first choice among our users, with 55% of people opting to fly with this airline when traveling to Santiago. Keep in mind that there are 3 different airlines that fly to Santiago on a routine basis, so you have a few additional options to choose from.

Historically, on average around 8% of flights between Mendoza and Santiago have experienced a delay on any given week. The average delay length over the past 12 months has been 100 minutes.

Generally, flights departing in the early afternoon tend to experience fewer delays. Flights in the evening have, in the past, seen delays more frequently in comparison.

Tuesday is statistically the day of the week which experiences the fewest number of delays on this flight route. Monday has historically seen more delays on average compared to the rest of the week.

According to our data, Sky Airline have had the least number of delays on this route over the last 12 months; with about 6% of their flights experiencing any sort of delay.

As of May 2026, there are 3 flights per day flying from Mendoza to Santiago. The most common time of day flights depart is 7:00PM, with 69% of flights taking off in the evening.

As of May 2026, there are 22 flights per week flying from Mendoza to Santiago. The most common day of the week flights depart is Fri, with 41% of flights taking off on this day.