Cheap flights from Massachusetts to Panama from $126

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Massachusetts to Panama departing on 3/3. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Multiple Airlines Logo
10:52 am - 8:19 pm
ALB
-
PTY
10h 27m
1 stop
Multiple Airlines Logo
12:03 pm - 10:02 am
PTY
-
ALB
20h 59m
1 stop
$537Multiple Airlines
Mon, Mar 16 - Thu, Mar 19
United Airlines Logo
7:33 pm - 2:14 pm
ALB
-
PTY
19h 41m
2 stops
United Airlines Logo
10:55 pm - 3:12 pm
PTY
-
ALB
15h 17m
2 stops
$543United Airlines
Mon, Apr 13 - Mon, Apr 27
American Airlines Logo
5:45 am - 12:46 pm
BDL
-
PTY
8h 01m
1 stop
American Airlines Logo
1:49 pm - 11:59 pm
PTY
-
BDL
9h 10m
1 stop
$553American Airlines
Thu, May 7 - Tue, May 12
Copa Airlines Logo
7:24 pm - 7:02 pm
ALB
-
PTY
24h 38m
2 stops
Copa Airlines Logo
3:41 pm - 9:13 pm
PTY
-
ALB
28h 32m
2 stops
$555Copa Airlines
Wed, Mar 18 - Thu, Mar 26
Avianca Logo
8:45 am - 1:05 am
BOS
-
PTY
17h 20m
1 stop
Avianca Logo
3:50 pm - 2:50 pm
PTY
-
BOS
22h 00m
1 stop
$557Avianca
Thu, May 21 - Thu, May 28
Avianca Logo
4:25 pm - 10:30 am
BOS
-
PTY
19h 05m
1 stop
Avianca Logo
8:10 pm - 2:50 pm
PTY
-
BOS
17h 40m
1 stop
$560Avianca
Wed, Mar 18 - Sat, Mar 28
LATAM Airlines Logo
2:12 pm - 1:03 pm
ALB
-
PTY
23h 51m
2 stops
LATAM Airlines Logo
2:28 pm - 12:12 pm
PTY
-
ALB
20h 44m
1 stop
$563LATAM Airlines
Mon, Mar 16 - Thu, Mar 19
American Airlines Logo
5:43 am - 12:41 pm
BDL
-
PTY
7h 58m
1 stop
American Airlines Logo
1:49 pm - 11:59 pm
PTY
-
BDL
9h 10m
1 stop
$573American Airlines
Mon, Mar 30 - Wed, Apr 8
Copa Airlines Logo
6:00 am - 6:38 pm
ALB
-
PTY
13h 38m
1 stop
Copa Airlines Logo
3:41 pm - 9:13 pm
PTY
-
ALB
28h 32m
2 stops
$593Copa Airlines
Wed, Mar 18 - Thu, Mar 26
LATAM Airlines Logo
6:10 am - 1:03 pm
ALB
-
PTY
7h 53m
1 stop
LATAM Airlines Logo
2:28 pm - 12:12 pm
PTY
-
ALB
20h 44m
1 stop
$617LATAM Airlines
Wed, Mar 18 - Thu, Mar 26

United Airlines flights from Massachusetts to Panama

Our best United Airlines deals on Massachusetts to Panama flight tickets
United Airlines
Mar 14
ALB8:14 amAlbany Intl
20h 56m
2 stops
PTY4:10 amPanama City Tocumen Intl
Mar 24
PTY3:41 pmPanama City Tocumen Intl
21h 25m
2 stops
ALB2:06 pmAlbany Intl
$543
United Airlines
Apr 7
BOS9:41 amBoston Logan Intl
9h 56m
1 stop
PTY6:37 pmPanama City Tocumen Intl
Apr 14
PTY10:55 pmPanama City Tocumen Intl
9h 16m
1 stop
BOS9:11 amBoston Logan Intl
$555
United Airlines
Mar 24
BDL6:00 amHartford Bradley Intl
13h 38m
2 stops
PTY6:38 pmPanama City Tocumen Intl
Mar 31
PTY10:55 pmPanama City Tocumen Intl
17h 37m
2 stops
BDL5:32 pmHartford Bradley Intl
$557

Copa Airlines flights from Massachusetts to Panama

Our best Copa Airlines deals on Massachusetts to Panama flight tickets
Copa Airlines
Mar 18
ALB7:24 pmAlbany Intl
24h 38m
2 stops
PTY7:02 pmPanama City Tocumen Intl
Mar 26
PTY3:41 pmPanama City Tocumen Intl
28h 32m
2 stops
ALB9:13 pmAlbany Intl
$555
Copa Airlines
Apr 13
BOS3:51 pmBoston Logan Intl
5h 50m
PTY8:41 pmPanama City Tocumen Intl
Apr 17
PTY4:18 pmPanama City Tocumen Intl
5h 51m
BOS11:09 pmBoston Logan Intl
$576
Copa Airlines
Mar 18
ALB6:00 amAlbany Intl
13h 38m
1 stop
PTY6:38 pmPanama City Tocumen Intl
Mar 26
PTY3:41 pmPanama City Tocumen Intl
28h 32m
2 stops
ALB9:13 pmAlbany Intl
$593

momondo Fare Finder

 
Customize your flight search to find flights from Massachusetts to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Massachusetts to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

AlbanyPanama City

ALB - PTY

ALBPTY

Albany Intl

Mon 3/16

10:52 am-8:19 pm

1 stop10h 27m

Panama City Tocumen Intl

Thu 3/19

12:03 pm-10:02 am

1 stop20h 59m

$537

AlbanyPanama City

ALB - PTY

ALBPTY

Albany Intl

Mon 4/13

7:33 pm-2:14 pm

2 stops19h 41m

Panama City Tocumen Intl

Mon 4/27

10:55 pm-3:12 pm

2 stops15h 17m

$543

HartfordPanama City

BDL - PTY

BDLPTY

Hartford Bradley Intl

Thu 5/7

5:45 am-12:46 pm

1 stop8h 01m

Panama City Tocumen Intl

Tue 5/12

1:49 pm-11:59 pm

1 stop9h 10m

$553

AlbanyPanama City

ALB - PTY

ALBPTY

Albany Intl

Wed 3/18

7:24 pm-7:02 pm

2 stops24h 38m

Panama City Tocumen Intl

Thu 3/26

3:41 pm-9:13 pm

2 stops28h 32m

$555

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Thu 5/21

8:45 am-1:05 am

1 stop17h 20m

Panama City Tocumen Intl

Thu 5/28

3:50 pm-2:50 pm

1 stop22h 00m

$557

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Wed 3/18

4:25 pm-10:30 am

1 stop19h 05m

Panama City Tocumen Intl

Sat 3/28

8:10 pm-2:50 pm

1 stop17h 40m

$560

AlbanyPanama City

ALB - PTY

ALBPTY

Albany Intl

Mon 3/16

2:12 pm-1:03 pm

2 stops23h 51m

Panama City Tocumen Intl

Thu 3/19

2:28 pm-12:12 pm

1 stop20h 44m

$563

HartfordPanama City

BDL - PTY

BDLPTY

Hartford Bradley Intl

Mon 3/30

5:43 am-12:41 pm

1 stop7h 58m

Panama City Tocumen Intl

Wed 4/8

1:49 pm-11:59 pm

1 stop9h 10m

$573

AlbanyPanama City

ALB - PTY

ALBPTY

Albany Intl

Wed 3/18

6:00 am-6:38 pm

1 stop13h 38m

Panama City Tocumen Intl

Thu 3/26

3:41 pm-9:13 pm

2 stops28h 32m

$593

AlbanyPanama City

ALB - PTY

ALBPTY

Albany Intl

Wed 3/18

6:10 am-1:03 pm

1 stop7h 53m

Panama City Tocumen Intl

Thu 3/26

2:28 pm-12:12 pm

1 stop20h 44m

$617

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Panama from

How to get the cheapest flight ticket from Massachusetts to Panama

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Panama?

The month of October is, on average, the cheapest month to fly to Panama from Massachusetts, with most prices found around $559. If you don’t want to visit Panama in October, then you should wait until May to fly from Massachusetts, when ticket prices are also cheap, with an average price of $576.

What is the cheapest day to depart on your flight to Panama?

According to our data, Tuesday is the cheapest day to fly to Panama from Massachusetts. The lowest ticket price found for a Tuesday departure recently was $569. Keep in mind that prices can always vary depending on your route and whether or not you are flying domestic or international. When flying out on a Friday, the most expensive travel day of the week, you can expect to see flight prices from Massachusetts to Panama for around $667.

What is the cheapest time of day to depart on your flight to Panama?

In the afternoon is the cheapest time of day to fly from Massachusetts to Panama when you can find flight prices for as low as $512. Flying to Panama in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Panama, so prices are often more expensive at around $651 per ticket.

What is the cheapest Massachusetts to Panama flight route?

Fly from Boston Logan Intl to Panama City Tocumen Intl for the best Massachusetts - Panama flight prices

How far in advance should I book a flight to Panama?

You are more likely to see cheaper flights to Panama from Massachusetts when booking weeks ahead of your departure date. In general, you can expect to find flights to Panama for around $612 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Panama from Massachusetts for as low as $498 on momondo.

What cabin class options are available on Massachusetts to Panama flights?

There are 3 cabin classes available to choose from on Massachusetts to Panama flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Massachusetts to Panama flights?

You could potentially save up to 13% on your flight if you consider stops on a Massachusetts to Panama flight.

Cheap Massachusetts to Panama flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Massachusetts to Panama

Best Price Found

$245

Fastest flight time

5h 34m

Direct flights

Every day

Airports in Panama

21 airports
The best one-way flight to Panama from Massachusetts in the past 72 hours is $245. The best round-trip flight deal from Massachusetts to Panama found on momondo in the last 72 hours is $337.
The fastest flight from Massachusetts to Panama takes 5h 34m
Direct flights go from Massachusetts to Panama every day.
There are 21 airports in Panama. From Massachusetts there are direct flights to Panama City Tocumen Intl (PTY).
  • When did momondo last update prices for flights from Massachusetts to Panama?

    Prices for flights from Massachusetts to Panama are refreshed on a daily basis.

  • How many operators does momondo search for flights from Massachusetts to Panama?

  • How old do you have to be to fly from Massachusetts to Panama?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Massachusetts to Panama.

  • What documentation or ID do you need to fly to Panama?

    The necessary travel and health documents for your Panama trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular plane model from Massachusetts to Panama?

Best airlines flying from Massachusetts to Panama

Compare and see reviews for airlines that fly from Massachusetts to Panama with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $281Free CancellationRating
7.2
11,218 reviews
Search American Airlines flights
AviancaPriceFrom $460Free CancellationRating
6.5
2,498 reviews
Search Avianca flights
Copa AirlinesPriceFrom $472Free CancellationRating
7.6
1,558 reviews
Search Copa Airlines flights
DeltaPriceFrom $487Free CancellationRating
7.9
8,139 reviews
Search Delta flights
United AirlinesPriceFrom $559Free CancellationRating
7.4
9,236 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Massachusetts to Panama?

We help find the flight that best suits your needs, momondo compares prices from hundreds of airlines and travel agents and helps you filter them to find the best flight from Massachusetts to Panama for you.

Can I find flights from Massachusetts to Panama with flexible booking policies on momondo?

All flight searches from Massachusetts to Panama on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Massachusetts to Panama?

Once all potential Massachusetts to Panama flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Massachusetts to Panama right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Massachusetts to Panama flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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1 adult
Thu 3/5
Thu 3/12

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