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Cheap flights from Madrid to Santiago from $493

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Madrid to Santiago departing on 11/19. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Madrid to Santiago

Cheap round-trip flights

Iberia Logo
4:55 pm - 10:10 amMAD-SCL
21h 15m1 stop
Iberia Logo
10:55 am - 5:35 amSCL-MAD
12h 40mnonstop
$865Iberia
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Mon, Mar 16 - Tue, Apr 7
Delta Logo
11:05 am - 7:40 amMAD-SCL
24h 35m1 stop
Delta Logo
11:10 pm - 9:15 amSCL-MAD
30h 05m1 stop
$867Delta
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Sun, Nov 2 - Sat, Nov 8
United Airlines Logo
11:05 am - 8:50 amMAD-SCL
49h 45m2 stops
United Airlines Logo
9:45 pm - 8:05 amSCL-MAD
54h 20m2 stops
$869United Airlines
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Wed, Nov 26 - Sun, Mar 15
Delta Logo
10:00 am - 7:40 amMAD-SCL
25h 40m2 stops
Delta Logo
11:10 pm - 7:10 pmSCL-MAD
40h 00m2 stops
$870Delta
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Thu, Oct 30 - Sun, Nov 23
Delta Logo
1:05 pm - 7:00 amMAD-SCL
45h 55m2 stops
Delta Logo
11:15 pm - 1:20 pmSCL-MAD
34h 05m2 stops
$872Delta
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Sat, Feb 7 - Fri, Feb 13
Delta Logo
11:15 am - 7:40 amMAD-SCL
24h 25m1 stop
Delta Logo
11:10 pm - 9:15 amSCL-MAD
30h 05m1 stop
$873Delta
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Tue, Nov 4 - Mon, Nov 17
LATAM Airlines Logo
11:05 am - 8:30 pmMAD-SCL
13h 25mnonstop
LATAM Airlines Logo
4:00 pm - 8:50 amSCL-MAD
12h 50mnonstop
$874LATAM Airlines
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Mon, Nov 17 - Sun, Nov 30
LATAM Airlines Logo
12:40 am - 5:20 pmMAD-SCL
20h 40m1 stop
LATAM Airlines Logo
1:35 pm - 2:00 pmSCL-MAD
18h 25m1 stop
$877LATAM Airlines
Find Deal
Sun, Mar 15 - Tue, Apr 7
LATAM Airlines Logo
10:55 pm - 2:10 pmMAD-SCL
19h 15m2 stops
LATAM Airlines Logo
4:00 pm - 2:00 pmSCL-MAD
16h 00m1 stop
$883LATAM Airlines
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Mon, Mar 16 - Tue, Apr 7
United Airlines Logo
11:15 am - 8:50 amMAD-SCL
25h 35m2 stops
United Airlines Logo
9:45 pm - 8:05 amSCL-MAD
54h 20m2 stops
$928United Airlines
Find Deal
Tue, Nov 25 - Sun, Mar 15

Delta flights from Madrid to Santiago

Our best Delta deals on Madrid to Santiago flight tickets
Delta
Nov 2
MAD11:05 amMadrid Barajas
24h 35m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Nov 8
SCL11:10 pmSantiago Arturo Merino Benitez
30h 05m
1 stop
MAD9:15 amMadrid Barajas
$867
Find similar
Delta
Oct 30
MAD10:00 amMadrid Barajas
25h 40m
2 stops
SCL7:40 amSantiago Arturo Merino Benitez
Nov 23
SCL11:10 pmSantiago Arturo Merino Benitez
40h 00m
2 stops
MAD7:10 pmMadrid Barajas
$870
Find similar
Delta
Sep 30
MAD10:05 amMadrid Barajas
25h 55m
2 stops
SCL7:00 amSantiago Arturo Merino Benitez
Oct 13
SCL9:40 pmSantiago Arturo Merino Benitez
40h 40m
2 stops
MAD7:20 pmMadrid Barajas
$871
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LATAM Airlines flights from Madrid to Santiago

Our best LATAM Airlines deals on Madrid to Santiago flight tickets
LATAM Airlines
Nov 17
MAD11:05 amMadrid Barajas
13h 25m
SCL8:30 pmSantiago Arturo Merino Benitez
Nov 30
SCL4:00 pmSantiago Arturo Merino Benitez
12h 50m
MAD8:50 amMadrid Barajas
$874
Find similar
LATAM Airlines
Mar 15
MAD12:40 amMadrid Barajas
20h 40m
1 stop
SCL5:20 pmSantiago Arturo Merino Benitez
Apr 7
SCL1:35 pmSantiago Arturo Merino Benitez
18h 25m
1 stop
MAD2:00 pmMadrid Barajas
$877
Find similar
LATAM Airlines
Mar 16
MAD10:55 pmMadrid Barajas
19h 15m
2 stops
SCL2:10 pmSantiago Arturo Merino Benitez
Apr 7
SCL4:00 pmSantiago Arturo Merino Benitez
16h 00m
1 stop
MAD2:00 pmMadrid Barajas
$883
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 3/16

4:55 pm-10:10 am

1 stop21h 15m

Santiago Arturo Merino Benitez

Tue 4/7

10:55 am-5:35 am

Nonstop12h 40m

$865

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 11/2

11:05 am-7:40 am

1 stop24h 35m

Santiago Arturo Merino Benitez

Sat 11/8

11:10 pm-9:15 am

1 stop30h 05m

$867

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 11/26

11:05 am-8:50 am

2 stops49h 45m

Santiago Arturo Merino Benitez

Sun 3/15

9:45 pm-8:05 am

2 stops54h 20m

$869

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 10/30

10:00 am-7:40 am

2 stops25h 40m

Santiago Arturo Merino Benitez

Sun 11/23

11:10 pm-7:10 pm

2 stops40h 00m

$870

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sat 2/7

1:05 pm-7:00 am

2 stops45h 55m

Santiago Arturo Merino Benitez

Fri 2/13

11:15 pm-1:20 pm

2 stops34h 05m

$872

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 11/4

11:15 am-7:40 am

1 stop24h 25m

Santiago Arturo Merino Benitez

Mon 11/17

11:10 pm-9:15 am

1 stop30h 05m

$873

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 11/17

11:05 am-8:30 pm

Nonstop13h 25m

Santiago Arturo Merino Benitez

Sun 11/30

4:00 pm-8:50 am

Nonstop12h 50m

$874

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 3/15

12:40 am-5:20 pm

1 stop20h 40m

Santiago Arturo Merino Benitez

Tue 4/7

1:35 pm-2:00 pm

1 stop18h 25m

$877

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 3/16

10:55 pm-2:10 pm

2 stops19h 15m

Santiago Arturo Merino Benitez

Tue 4/7

4:00 pm-2:00 pm

1 stop16h 00m

$883

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 11/25

11:15 am-8:50 am

2 stops25h 35m

Santiago Arturo Merino Benitez

Sun 3/15

9:45 pm-8:05 am

2 stops54h 20m

$928

Flights are sorted by cheapest round-trip flights first.

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See travel insights to Santiago from

How to get the cheapest flight ticket from Madrid to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Madrid and Santiago?

What is the cheapest month to fly to Santiago?

In general, March is the cheapest month to fly from Madrid to Santiago. Due to it being the ‘off-season’ during this time, you can expect flight prices to be around $895. If you don’t want to visit Santiago in March, then you should wait until April to fly from Madrid, when ticket prices are also cheap, with an average price of $944.

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $1,160. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Saturday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Saturday is $1,528.

What is the cheapest time of day to depart on your flight to Santiago?

At noon is the cheapest time of day to fly from Madrid to Santiago when you can find flight prices for as low as $1,171. Flying to Santiago at noon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,342 per ticket.

What is the cheapest Madrid Barajas to Santiago Arturo Merino Benitez flight route?

Fly from Madrid Barajas to Santiago Arturo Merino Benitez for the best Madrid Barajas - Santiago Arturo Merino Benitez flight prices

How far in advance should I book a flight to Santiago?

You are more likely to see cheaper flights to Santiago from Madrid when booking weeks ahead of your departure date. In general, you can expect to find flights to Santiago for around $1,084 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Santiago from Madrid for as low as $935 on momondo.

What cabin class options are available on Madrid Barajas to Santiago Arturo Merino Benitez flights?

There are 3 cabin classes available to choose from on Madrid Barajas to Santiago Arturo Merino Benitez flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

Can stopping save me money on Madrid to Santiago flights?

You could potentially save up to 19% on your flight if you consider stops on a Madrid to Santiago flight.

How have Madrid to Santiago flight prices changed over time?

As of September 2025, prices for Madrid to Santiago flights are approximately 12% cheaper when compared to flights at the same time last year.

When to book flights from Madrid to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Madrid to Santiago according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Madrid to Santiago (MAD to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Madrid to Santiago

Best Price Found

$687

Fastest flight time

13h 15m

Direct flights

Every day

Airports in Santiago

1 airport
The best one-way flight to Santiago from Madrid in the past 72 hours is $687. The best round-trip flight deal from Madrid to Santiago found on momondo in the last 72 hours is $1,240.
The fastest flight from Madrid to Santiago takes 13h 15m
Direct flights go from Madrid to Santiago every day.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
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  • How far is Madrid Barajas to Santiago Arturo Merino Benitez by plane?

    A flight from Madrid Barajas to Santiago Arturo Merino Benitez will travel around 6644.6 mi. 13h 25m is a normal flight duration for this route.

  • When did momondo last update prices for flights from Madrid Barajas Airport to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Madrid Barajas Airport to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Madrid Barajas Airport to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Madrid Barajas Airport to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Madrid Barajas Airport to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The travel and health documents required for your trip to Santiago Arturo Merino Benitez Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santiago Arturo Merino Benitez Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular plane model from Madrid to Santiago?

  • What is the most popular airline from Madrid to Santiago?

Best airlines flying from Madrid to Santiago

Compare and see reviews for airlines that fly from Madrid to Santiago with momondo
Airline
Rating
Free Cancellation
Price
IberiaPriceFrom $706Free CancellationRating
7.0
2,925 reviews
Search Iberia flights
British AirwaysPriceFrom $714Free CancellationRating
6.7
7,367 reviews
Search British Airways flights
LATAM AirlinesPriceFrom $719Free CancellationRating
7.5
1,849 reviews
Search LATAM Airlines flights
AviancaPriceFrom $804Free CancellationRating
6.7
2,436 reviews
Search Avianca flights

  • LATAM Airlines Flights From Madrid to Santiago

    LATAM Airlines flight deals from Madrid to Santiago start from $719 round-trip. Over the 28 LATAM Airlines flights for this route in a normal week, average airfare is usually $1,319 round-trip - but some users have found much cheaper deals with momondo.

  • Iberia Flights From Madrid to Santiago

    The best Iberia deal for Madrid to Santiago flight tickets found on momondo in the last 72 hours was $706, round-trip. It should be noted that an average Iberia flight deal for this route in this time was higher, at $1,122 round-trip. Iberia operates 20 flights out of Madrid into Santiago in an average week, so prices vary by time and availability. 2,925 Iberia reviews by users on momondo have scored the airline at 7.0/10.

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Madrid to Santiago?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Madrid to Santiago. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Madrid to Santiago with flexible booking policies on momondo?

Flights from Madrid to Santiago with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Madrid to Santiago?

momondo offers useful filters to help you find the right flight. Choose specific flight times, airports or even what payment method you prefer. We have numerous options to help you book your ideal flight from Madrid to Santiago.

I’m not ready to book a flight from Madrid to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Madrid to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.

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