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Cheap flights from Louisville to Santo Domingo from $168

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Santo Domingo departing on 12/5. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
10:55 am - 5:50 pmSDF-SDQ
5h 55m1 stop
Spirit Airlines Logo
6:55 pm - 9:54 amSDQ-SDF
15h 59m1 stop
$462Spirit Airlines
Find Deal
mié., feb. 11 - dom., feb. 15
American Airlines Logo
6:33 am - 11:00 pmSDF-SDQ
15h 27m1 stop
American Airlines Logo
7:50 am - 12:14 amSDQ-SDF
16h 24m1 stop
$518American Airlines
Find Deal
jue., mar. 5 - jue., mar. 19
American Airlines Logo
6:00 am - 2:05 pmSDF-SDQ
7h 05m1 stop
American Airlines Logo
1:19 pm - 11:41 pmSDQ-SDF
11h 22m1 stop
$528American Airlines
Find Deal
vie., nov. 14 - lun., nov. 17
American Airlines Logo
6:00 am - 11:45 pmSDF-SDQ
16h 45m1 stop
American Airlines Logo
1:19 pm - 11:59 pmSDQ-SDF
11h 40m2 stops
$532American Airlines
Find Deal
vie., nov. 14 - lun., nov. 17
Delta Logo
7:00 am - 1:15 pmSDF-SDQ
6h 15m1 stop
Delta Logo
2:40 pm - 11:56 pmSDQ-SDF
9h 16m1 stop
$548Delta
Find Deal
mié., abr. 1 - lun., abr. 6
Delta Logo
6:00 am - 5:35 pmSDF-SDQ
11h 35m2 stops
Delta Logo
2:40 pm - 11:56 pmSDQ-SDF
9h 16m1 stop
$552Delta
Find Deal
mié., abr. 1 - lun., abr. 6
United Airlines Logo
6:28 am - 3:06 pmSDF-SDQ
7h 38m1 stop
United Airlines Logo
2:53 pm - 11:23 pmSDQ-SDF
9h 30m1 stop
$628United Airlines
Find Deal
jue., feb. 5 - lun., feb. 9
United Airlines Logo
8:29 am - 11:46 pmSDF-SDQ
14h 17m2 stops
United Airlines Logo
2:53 pm - 11:23 pmSDQ-SDF
9h 30m1 stop
$632United Airlines
Find Deal
jue., feb. 5 - lun., feb. 9
Multiple Airlines Logo
2:55 pm - 10:11 amSDF-SDQ
18h 16m2 stops
Multiple Airlines Logo
4:31 pm - 11:25 amSDQ-SDF
19h 54m1 stop
$1,014Multiple Airlines
Find Deal
jue., dic. 25 - mar., ene. 6
Multiple Airlines Logo
2:55 pm - 10:11 amSDF-SDQ
18h 16m2 stops
Multiple Airlines Logo
3:47 am - 11:25 amSDQ-SDF
8h 38m1 stop
$1,088Multiple Airlines
Find Deal
jue., dic. 25 - lun., ene. 5

Delta flights from Louisville to Santo Domingo

Our best Delta deals on Louisville to Santo Domingo flight tickets
Delta
Apr 1
SDF7:00 amLouisville Intl
6h 15m
1 stop
SDQ1:15 pmSanto Domingo Las Americas
Apr 6
SDQ2:40 pmSanto Domingo Las Americas
9h 16m
1 stop
SDF11:56 pmLouisville Intl
$548
Find similar
Delta
Apr 1
SDF6:00 amLouisville Intl
11h 35m
2 stops
SDQ5:35 pmSanto Domingo Las Americas
Apr 6
SDQ2:40 pmSanto Domingo Las Americas
9h 16m
1 stop
SDF11:56 pmLouisville Intl
$552
Find similar
Delta
Mar 2
SDF6:00 amLouisville Intl
7h 15m
1 stop
SDQ2:15 pmSanto Domingo Las Americas
Mar 6
SDQ8:00 pmSanto Domingo Las Americas
16h 37m
2 stops
SDF11:37 amLouisville Intl
$572
Find similar

Spirit Airlines flights from Louisville to Santo Domingo

Our best Spirit Airlines deals on Louisville to Santo Domingo flight tickets
Spirit Airlines
Feb 11
SDF10:55 amLouisville Intl
5h 55m
1 stop
SDQ5:50 pmSanto Domingo Las Americas
Feb 15
SDQ6:55 pmSanto Domingo Las Americas
15h 59m
1 stop
SDF9:54 amLouisville Intl
$462
Find similar
Spirit Airlines
Dec 25
SDF12:20 pmLouisville Intl
13h 22m
1 stop
SDQ2:42 amSanto Domingo Las Americas
Jan 5
SDQ3:47 amSanto Domingo Las Americas
8h 38m
1 stop
SDF11:25 amLouisville Intl
$966
Find similar
Spirit Airlines
Dec 23
SDF12:20 pmLouisville Intl
13h 22m
1 stop
SDQ2:42 amSanto Domingo Las Americas
Jan 2
SDQ3:47 amSanto Domingo Las Americas
8h 38m
1 stop
SDF11:25 amLouisville Intl
$1,026
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated octubre 14, 2025.
Use the filters below to find and compare flights from Louisville to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

mié. 2/11

10:55 am-5:50 pm

1 stop5h 55m

Santo Domingo Las Americas

dom. 2/15

6:55 pm-9:54 am

1 stop15h 59m

$462

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

jue. 3/5

6:33 am-11:00 pm

1 stop15h 27m

Santo Domingo Las Americas

jue. 3/19

7:50 am-12:14 am

1 stop16h 24m

$518

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

vie. 11/14

6:00 am-2:05 pm

1 stop7h 05m

Santo Domingo Las Americas

lun. 11/17

1:19 pm-11:41 pm

1 stop11h 22m

$528

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

vie. 11/14

6:00 am-11:45 pm

1 stop16h 45m

Santo Domingo Las Americas

lun. 11/17

1:19 pm-11:59 pm

2 stops11h 40m

$532

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

mié. 4/1

7:00 am-1:15 pm

1 stop6h 15m

Santo Domingo Las Americas

lun. 4/6

2:40 pm-11:56 pm

1 stop9h 16m

$548

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

mié. 4/1

6:00 am-5:35 pm

2 stops11h 35m

Santo Domingo Las Americas

lun. 4/6

2:40 pm-11:56 pm

1 stop9h 16m

$552

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

jue. 2/5

6:28 am-3:06 pm

1 stop7h 38m

Santo Domingo Las Americas

lun. 2/9

2:53 pm-11:23 pm

1 stop9h 30m

$628

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

jue. 2/5

8:29 am-11:46 pm

2 stops14h 17m

Santo Domingo Las Americas

lun. 2/9

2:53 pm-11:23 pm

1 stop9h 30m

$632

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

jue. 12/25

2:55 pm-10:11 am

2 stops18h 16m

Santo Domingo Las Americas

mar. 1/6

4:31 pm-11:25 am

1 stop19h 54m

$1,014

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

jue. 12/25

2:55 pm-10:11 am

2 stops18h 16m

Santo Domingo Las Americas

lun. 1/5

3:47 am-11:25 am

1 stop8h 38m

$1,088

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Louisville to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Thursday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $524. The most expensive day to fly to Santo Domingo is Saturday, with ticket prices averaging around $899.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the evening when flights can be purchased for as low as $467. Try not to purchase tickets in the morning because they tend to be around $630. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Louisville to Santo Domingo flights?

You could potentially save up to 9% on your flight if you consider stops on a Louisville to Santo Domingo flight.

When to book flights from Louisville to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Santo Domingo (SDF to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Santo Domingo

Direct flights

None
There are no direct flights from Louisville to Santo Domingo. There are no popular flight routes from Louisville to Santo Domingo.
Search flight deals

  • How far is Louisville Intl to Santo Domingo Las Americas by plane?

    The distance between Louisville Intl and Santo Domingo Las Americas is about 1663.7 mi. In terms of flight time, this usually takes a little over 5h 55m.

  • When did momondo last update prices for flights from Louisville Intl Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Louisville Intl Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to Santo Domingo?

Best airlines flying from Louisville to Santo Domingo

Compare and see reviews for airlines that fly from Louisville to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $513Free CancellationRating
7.9
7,975 reviews
Search Delta flights
American AirlinesPriceFrom $514Free CancellationRating
7.2
11,042 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Santo Domingo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santo Domingo from Louisville.

Can I find flights from Louisville to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from Louisville.

I’m not ready to book a flight from Louisville to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Louisville to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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