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Cheap flights from Louisville to Santo Domingo from $532

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Santo Domingo departing on 1/9. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
11:21 am - 11:26 pmSDF-SDQ
11h 05m1 stop
American Airlines Logo
6:29 pm - 12:25 pmSDQ-SDF
18h 56m2 stops
$532American Airlines
Find Deal
Fri, Jan 9 - Fri, Jan 16
Multiple Airlines Logo
3:40 pm - 2:54 amSDF-SDQ
34h 14m2 stops
Multiple Airlines Logo
4:21 pm - 10:49 pmSDQ-SDF
7h 28m1 stop
$538Multiple Airlines
Find Deal
Tue, Dec 23 - Tue, Dec 30
Multiple Airlines Logo
2:55 pm - 4:49 pmSDF-SDQ
24h 54m2 stops
Multiple Airlines Logo
3:59 am - 10:49 pmSDQ-SDF
19h 50m1 stop
$551Multiple Airlines
Find Deal
Tue, Dec 23 - Mon, Dec 29
Delta Logo
5:35 am - 2:21 pmSDF-SDQ
7h 46m1 stop
Delta Logo
3:46 pm - 11:50 pmSDQ-SDF
9h 04m1 stop
$568Delta
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Sun, Jan 25 - Thu, Jan 29
Delta Logo
5:35 am - 12:30 amSDF-SDQ
17h 55m2 stops
Delta Logo
3:46 pm - 11:50 pmSDQ-SDF
9h 04m1 stop
$572Delta
Find Deal
Sun, Jan 25 - Thu, Jan 29
Spirit Airlines Logo
5:05 am - 3:23 pmSDF-SDQ
9h 18m1 stop
Spirit Airlines Logo
4:21 pm - 10:49 pmSDQ-SDF
7h 28m1 stop
$604Spirit Airlines
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Tue, Dec 23 - Tue, Dec 30
Delta Logo
5:35 am - 7:14 pmSDF-SDQ
12h 39m2 stops
Delta Logo
7:31 am - 5:01 pmSDQ-SDF
10h 30m2 stops
$607Delta
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Sun, Jan 25 - Thu, Jan 29
Spirit Airlines Logo
5:05 am - 2:54 amSDF-SDQ
20h 49m1 stop
Spirit Airlines Logo
3:59 am - 10:49 pmSDQ-SDF
19h 50m1 stop
$612Spirit Airlines
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Tue, Dec 23 - Mon, Dec 29
American Airlines Logo
6:00 am - 2:00 pmSDF-SDQ
7h 00m1 stop
American Airlines Logo
6:00 am - 11:59 pmSDQ-SDF
18h 59m1 stop
$625American Airlines
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Fri, Jan 9 - Fri, Jan 16
United Airlines Logo
1:50 pm - 11:46 pmSDF-SDQ
8h 56m1 stop
United Airlines Logo
2:53 pm - 11:23 pmSDQ-SDF
9h 30m1 stop
$628United Airlines
Find Deal
Thu, Feb 5 - Mon, Feb 9

American Airlines flights from Louisville to Santo Domingo

Our best American Airlines deals on Louisville to Santo Domingo flight tickets
American Airlines
Jan 9
SDF11:21 amLouisville Intl
11h 05m
1 stop
SDQ11:26 pmSanto Domingo Las Americas
Jan 16
SDQ6:29 pmSanto Domingo Las Americas
18h 56m
2 stops
SDF12:25 pmLouisville Intl
$532
Find similar
American Airlines
Nov 29
SDF6:00 amLouisville Intl
16h 45m
1 stop
SDQ11:45 pmSanto Domingo Las Americas
Dec 1
SDQ4:45 pmSanto Domingo Las Americas
7h 58m
1 stop
SDF11:43 pmLouisville Intl
$588
Find similar
American Airlines
Nov 29
SDF6:25 amLouisville Intl
8h 20m
2 stops
SDQ3:45 pmSanto Domingo Las Americas
Dec 1
SDQ4:45 pmSanto Domingo Las Americas
7h 58m
1 stop
SDF11:43 pmLouisville Intl
$592
Find similar

United Airlines flights from Louisville to Santo Domingo

Our best United Airlines deals on Louisville to Santo Domingo flight tickets
United Airlines
Feb 5
SDF1:50 pmLouisville Intl
8h 56m
1 stop
SDQ11:46 pmSanto Domingo Las Americas
Feb 9
SDQ2:53 pmSanto Domingo Las Americas
9h 30m
1 stop
SDF11:23 pmLouisville Intl
$628
Find similar
United Airlines
Feb 5
SDF5:35 amLouisville Intl
17h 11m
2 stops
SDQ11:46 pmSanto Domingo Las Americas
Feb 9
SDQ2:53 pmSanto Domingo Las Americas
9h 30m
1 stop
SDF11:23 pmLouisville Intl
$632
Find similar
United Airlines
Feb 5
SDF8:29 amLouisville Intl
14h 17m
2 stops
SDQ11:46 pmSanto Domingo Las Americas
Feb 9
SDQ6:00 amSanto Domingo Las Americas
17h 30m
2 stops
SDF10:30 pmLouisville Intl
$642
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Louisville to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Fri 1/9

11:21 am-11:26 pm

1 stop11h 05m

Santo Domingo Las Americas

Fri 1/16

6:29 pm-12:25 pm

2 stops18h 56m

$532

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Tue 12/23

3:40 pm-2:54 am

2 stops34h 14m

Santo Domingo Las Americas

Tue 12/30

4:21 pm-10:49 pm

1 stop7h 28m

$538

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Tue 12/23

2:55 pm-4:49 pm

2 stops24h 54m

Santo Domingo Las Americas

Mon 12/29

3:59 am-10:49 pm

1 stop19h 50m

$551

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Sun 1/25

5:35 am-2:21 pm

1 stop7h 46m

Santo Domingo Las Americas

Thu 1/29

3:46 pm-11:50 pm

1 stop9h 04m

$568

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Sun 1/25

5:35 am-12:30 am

2 stops17h 55m

Santo Domingo Las Americas

Thu 1/29

3:46 pm-11:50 pm

1 stop9h 04m

$572

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Tue 12/23

5:05 am-3:23 pm

1 stop9h 18m

Santo Domingo Las Americas

Tue 12/30

4:21 pm-10:49 pm

1 stop7h 28m

$604

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Sun 1/25

5:35 am-7:14 pm

2 stops12h 39m

Santo Domingo Las Americas

Thu 1/29

7:31 am-5:01 pm

2 stops10h 30m

$607

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Tue 12/23

5:05 am-2:54 am

1 stop20h 49m

Santo Domingo Las Americas

Mon 12/29

3:59 am-10:49 pm

1 stop19h 50m

$612

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Fri 1/9

6:00 am-2:00 pm

1 stop7h 00m

Santo Domingo Las Americas

Fri 1/16

6:00 am-11:59 pm

1 stop18h 59m

$625

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 2/5

1:50 pm-11:46 pm

1 stop8h 56m

Santo Domingo Las Americas

Mon 2/9

2:53 pm-11:23 pm

1 stop9h 30m

$628

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Louisville to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Louisville and Santo Domingo?

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Thursday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $524. The most expensive day to fly to Santo Domingo is Saturday, with ticket prices averaging around $899.

What is the cheapest time of day to depart on your flight to Santo Domingo?

The cheapest time of day to fly to Santo Domingo is in the evening when flights can be purchased for as low as $467. Try not to purchase tickets in the morning because they tend to be around $630. Of course, these prices can vary depending on the time of year and what airport you fly to.

Can stopping save me money on Louisville to Santo Domingo flights?

You could potentially save up to 9% on your flight if you consider stops on a Louisville to Santo Domingo flight.

When to book flights from Louisville to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Santo Domingo (SDF to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Santo Domingo

Fastest flight time

6h 21m

Direct flights

None
The fastest flight from Louisville to Santo Domingo takes 6h 21m
There are no direct flights from Louisville to Santo Domingo. There are no popular flight routes from Louisville to Santo Domingo.
Search flight deals

  • How far is Louisville Intl to Santo Domingo Las Americas by plane?

    The distance between Louisville Intl and Santo Domingo Las Americas is about 1663.7 mi. In terms of flight time, this usually takes a little over 7h 00m.

  • When did momondo last update prices for flights from Louisville Intl Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Louisville Intl Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to Santo Domingo?

Best airlines flying from Louisville to Santo Domingo

Compare and see reviews for airlines that fly from Louisville to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $514Free CancellationRating
7.2
11,038 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Santo Domingo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santo Domingo from Louisville.

Can I find flights from Louisville to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from Louisville.

I’m not ready to book a flight from Louisville to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Louisville to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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