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Cheap flights from Louisville to Santo Domingo from $339

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Louisville to Santo Domingo departing on 3/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Louisville to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
Spirit Airlines Logo
3:33 pm - 1:25 pm
SDF
-
SDQ
21h 52m
1 stop
Spirit Airlines Logo
2:59 am - 2:33 pm
SDQ
-
SDF
11h 34m
1 stop
$339Spirit Airlines
Thu, Mar 12 - Wed, Mar 18
Spirit Airlines Logo
3:33 pm - 2:20 pm
SDF
-
SDQ
21h 47m
1 stop
Spirit Airlines Logo
2:59 am - 2:33 pm
SDQ
-
SDF
11h 34m
1 stop
$378Spirit Airlines
Thu, Mar 5 - Wed, Mar 18
Spirit Airlines Logo
1:19 pm - 2:20 pm
SDF
-
SDQ
24h 01m
2 stops
Spirit Airlines Logo
3:32 pm - 2:38 pm
SDQ
-
SDF
24h 06m
1 stop
$399Spirit Airlines
Fri, Feb 20 - Wed, Feb 25
Multiple Airlines Logo
3:33 pm - 10:41 am
SDF
-
SDQ
18h 08m
2 stops
Multiple Airlines Logo
2:59 am - 2:33 pm
SDQ
-
SDF
11h 34m
1 stop
$434Multiple Airlines
Thu, Mar 5 - Wed, Mar 18
Multiple Airlines Logo
9:30 am - 2:20 pm
SDF
-
SDQ
27h 50m
1 stop
Multiple Airlines Logo
3:32 pm - 2:38 pm
SDQ
-
SDF
24h 06m
1 stop
$453Multiple Airlines
Fri, Feb 20 - Wed, Feb 25
Spirit Airlines Logo
3:33 pm - 1:25 pm
SDF
-
SDQ
21h 52m
1 stop
Spirit Airlines Logo
2:30 pm - 11:08 am
SDQ
-
SDF
20h 38m
2 stops
$455Spirit Airlines
Thu, Mar 12 - Thu, Mar 19
Multiple Airlines Logo
3:33 pm - 4:26 pm
SDF
-
SDQ
24h 53m
3 stops
Multiple Airlines Logo
2:59 am - 2:33 pm
SDQ
-
SDF
11h 34m
1 stop
$496Multiple Airlines
Thu, Mar 12 - Wed, Mar 18
Delta Logo
6:35 am - 6:52 pm
SDF
-
SDQ
12h 17m
1 stop
Delta Logo
6:35 am - 8:42 pm
SDQ
-
SDF
14h 07m
1 stop
$549Delta
Thu, Apr 2 - Wed, Apr 8
American Airlines Logo
6:00 am - 5:50 pm
SDF
-
SDQ
10h 50m
2 stops
American Airlines Logo
2:16 pm - 12:27 am
SDQ
-
SDF
10h 11m
2 stops
$553American Airlines
Thu, Mar 5 - Thu, Mar 19
United Airlines Logo
9:00 am - 11:46 pm
SDF
-
SDQ
13h 46m
2 stops
United Airlines Logo
6:00 am - 8:09 pm
SDQ
-
SDF
15h 09m
2 stops
$578United Airlines
Fri, Feb 20 - Wed, Feb 25

United Airlines flights from Louisville to Santo Domingo

Our best United Airlines deals on Louisville to Santo Domingo flight tickets
United Airlines
Feb 20
SDF9:00 amLouisville Intl
13h 46m
2 stops
SDQ11:46 pmSanto Domingo Las Americas
Feb 25
SDQ6:00 amSanto Domingo Las Americas
15h 09m
2 stops
SDF8:09 pmLouisville Intl
$578
United Airlines
Feb 3
SDF6:28 amLouisville Intl
7h 38m
1 stop
SDQ3:06 pmSanto Domingo Las Americas
Feb 5
SDQ2:53 pmSanto Domingo Las Americas
9h 30m
1 stop
SDF11:23 pmLouisville Intl
$699
United Airlines
Feb 17
SDF5:35 amLouisville Intl
17h 11m
2 stops
SDQ11:46 pmSanto Domingo Las Americas
Feb 19
SDQ6:00 amSanto Domingo Las Americas
17h 13m
2 stops
SDF10:13 pmLouisville Intl
$703

Spirit Airlines flights from Louisville to Santo Domingo

Our best Spirit Airlines deals on Louisville to Santo Domingo flight tickets
Spirit Airlines
Mar 12
SDF3:33 pmLouisville Intl
21h 52m
1 stop
SDQ1:25 pmSanto Domingo Las Americas
Mar 18
SDQ2:59 amSanto Domingo Las Americas
11h 34m
1 stop
SDF2:33 pmLouisville Intl
$339
Spirit Airlines
Mar 5
SDF3:33 pmLouisville Intl
21h 47m
1 stop
SDQ2:20 pmSanto Domingo Las Americas
Mar 18
SDQ2:59 amSanto Domingo Las Americas
11h 34m
1 stop
SDF2:33 pmLouisville Intl
$378
Spirit Airlines
Feb 20
SDF1:19 pmLouisville Intl
24h 01m
2 stops
SDQ2:20 pmSanto Domingo Las Americas
Feb 25
SDQ3:32 pmSanto Domingo Las Americas
24h 06m
1 stop
SDF2:38 pmLouisville Intl
$399

momondo Fare Finder

 
Customize your flight search to find flights from Louisville to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Louisville to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 3/12

3:33 pm-1:25 pm

1 stop21h 52m

Santo Domingo Las Americas

Wed 3/18

2:59 am-2:33 pm

1 stop11h 34m

$339

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 3/5

3:33 pm-2:20 pm

1 stop21h 47m

Santo Domingo Las Americas

Wed 3/18

2:59 am-2:33 pm

1 stop11h 34m

$378

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Fri 2/20

1:19 pm-2:20 pm

2 stops24h 01m

Santo Domingo Las Americas

Wed 2/25

3:32 pm-2:38 pm

1 stop24h 06m

$399

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 3/5

3:33 pm-10:41 am

2 stops18h 08m

Santo Domingo Las Americas

Wed 3/18

2:59 am-2:33 pm

1 stop11h 34m

$434

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Fri 2/20

9:30 am-2:20 pm

1 stop27h 50m

Santo Domingo Las Americas

Wed 2/25

3:32 pm-2:38 pm

1 stop24h 06m

$453

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 3/12

3:33 pm-1:25 pm

1 stop21h 52m

Santo Domingo Las Americas

Thu 3/19

2:30 pm-11:08 am

2 stops20h 38m

$455

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 3/12

3:33 pm-4:26 pm

3 stops24h 53m

Santo Domingo Las Americas

Wed 3/18

2:59 am-2:33 pm

1 stop11h 34m

$496

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 4/2

6:35 am-6:52 pm

1 stop12h 17m

Santo Domingo Las Americas

Wed 4/8

6:35 am-8:42 pm

1 stop14h 07m

$549

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Thu 3/5

6:00 am-5:50 pm

2 stops10h 50m

Santo Domingo Las Americas

Thu 3/19

2:16 pm-12:27 am

2 stops10h 11m

$553

LouisvilleSanto Domingo

SDF - SDQ

SDFSDQ

Louisville Intl

Fri 2/20

9:00 am-11:46 pm

2 stops13h 46m

Santo Domingo Las Americas

Wed 2/25

6:00 am-8:09 pm

2 stops15h 09m

$578

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Louisville to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in November, then you should wait until September to fly from Louisville, when ticket prices are also cheap, with an average price of $534.

Can stopping save me money on Louisville to Santo Domingo flights?

You could potentially save up to 9% on your flight if you consider stops on a Louisville to Santo Domingo flight.

When to book flights from Louisville to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Louisville to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Louisville to Santo Domingo (SDF to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Louisville to Santo Domingo

Fastest flight time

7h 38m

Direct flights

None
The fastest flight from Louisville to Santo Domingo takes 7h 38m
There are no direct flights from Louisville to Santo Domingo. There are no popular flight routes from Louisville to Santo Domingo.
Search flight deals

  • How far is Louisville Intl to Santo Domingo Las Americas by plane?

    The distance between Louisville Intl and Santo Domingo Las Americas is about 1663.7 mi. In terms of flight time, this usually takes a little over 7h 38m.

  • When did momondo last update prices for flights from Louisville Intl Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Louisville Intl Airport to Santo Domingo Las Americas Airport were last updated today.

  • How many operators does momondo search for flights from Louisville Intl Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Louisville Intl Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Louisville Intl Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The required travel and health documents for your Santo Domingo Las Americas Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santo Domingo Las Americas Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular airline from Louisville to Santo Domingo?

Best airlines flying from Louisville to Santo Domingo

Compare and see reviews for airlines that fly from Louisville to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $517Free CancellationRating
7.2
11,201 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Louisville to Santo Domingo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santo Domingo from Louisville.

Can I find flights from Louisville to Santo Domingo with flexible booking policies on momondo?

Yes. All flights to Santo Domingo from Louisville on momondo can be compared and filtered by various policies on offer, including flexible booking.

How can momondo help me find flights from Louisville to Santo Domingo?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santo Domingo from Louisville.

I’m not ready to book a flight from Louisville to Santo Domingo right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Louisville to Santo Domingo flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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