Cheap flights from Louisville to Chicago from $109

The month of October is another great option to travel to Chicago O'Hare Intl Airport, with average flight prices from Louisville averaging around $246.

The cheapest day to depart on your flight to Chicago O'Hare Intl Airport is on a Friday when prices can be found for as low as $525. This is often the case because there is less demand to fly during this day of the week. On the other hand, Sunday is the most expensive day to depart from Louisville because it is more convenient for both business and leisure travelers. As a result, prices tend to be around $716.

Flying to Chicago O'Hare Intl Airport from Louisville in the morning is the least expensive time of day to depart. momondo users have found prices as low as $530 when looking at flights departing in the morning. Try not to purchase tickets at noon because they tend to be around $1,034. Of course, these prices can vary depending on the time of year and what airport you fly to.

Fly from Louisville Intl to Chicago O'Hare Intl for the best Louisville Intl - Chicago O'Hare Intl flight prices

You are more likely to see cheaper flights to Chicago O'Hare Intl Airport from Louisville when booking weeks ahead of your departure date. In general, you can expect to find flights to Chicago O'Hare Intl Airport for around $347 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Chicago O'Hare Intl Airport from Louisville for as low as $97 on momondo.

There are 4 cabin classes available to choose from on Louisville to Chicago O'Hare Intl Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 59% on your flight if you consider stops on a Louisville to Chicago O'Hare Intl Airport flight.

As of September 2026, prices for Louisville to Chicago O'Hare Intl Airport flights are approximately 0% more expensive when compared to flights at the same time last year.

United Airlines and Delta are the most popular carriers operating from Louisville Intl to Chicago O'Hare Intl

United Airlines, American Airlines and Contour are the top three most popular airlines that fly to Chicago O'Hare Intl Airport from Louisville according to our data. United Airlines is the first choice among our users, with 56% of people opting to fly with this airline when traveling to Chicago O'Hare Intl Airport. Keep in mind that there are 3 different airlines that fly to Chicago O'Hare Intl Airport on a routine basis, so you have a few additional options to choose from.

The number of flights available between Louisville and Chicago O'Hare Intl Airport is 9 per day as of September 2026. The most frequent departure time is 11:00AM, with 62% of daily flights leaving at noon.

As of September 2026, there are 69 flights per week flying from Louisville to Chicago O'Hare Intl Airport. The most common day of the week flights depart is Mon, with 55% of flights taking off on this day.