How do I get Price Alerts for flights from Knoxville to Santiago?

Price Alerts will notify you by email when the price for flights to Santiago from Knoxville decreases. To activate this, select your desired travel dates and search for offers. While browsing through offers you’ll see the Price Alert widget toggle. Click it to turn on notifications.

How can I save money on flights from Knoxville to Santiago with momondo?

Plan your trips smart with the “Price Forecast” feature, which uses flight data to help you pick the best days to fly for the lowest fares. Our “Price Calendar” helps you get the most for your money by showing you when it’s most advantageous to fly. Curate your own travel experiences for less with “Explore” . Expert travel hacks to fuel your next adventure are a click away with “Discover” by momondo. Set up our “Price Alerts” to track fare changes and book when prices are at their lowest point.

How does momondo find its flight prices?

We show prices from over 700+ competitors with a single click. With options from airlines and OTAs from across our 30 international markets, we are able to show you a diverse range of deals to create your adventure.

When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Santiago Arturo Merino Benitez Airport?

Prices for flights from Knoxville McGhee Tyson Airport to Santiago Arturo Merino Benitez Airport are updated daily.

How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Santiago Arturo Merino Benitez Airport?

There is 1 operator available for flights from Knoxville McGhee Tyson Airport to Santiago Arturo Merino Benitez Airport as of April 2026.

How old do you have to be to fly from Knoxville McGhee Tyson Airport to Santiago Arturo Merino Benitez Airport?

The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Santiago Arturo Merino Benitez Airport.

What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

$997 Cheap Flights from Knoxville to Santiago in 2026

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Find the cheapest flights from Knoxville to Santiago

Round-trip

One-way

Cheap round-trip flights

Enter your travel dates to find the best prices.

12:00 pm - 4:35 pm

TYS

SCL

27h 35m

2 stops

8:40 pm - 9:12 am

SCL

TYS

13h 32m

1 stop

$997LATAM Airlines

K, sept 30 - R, okt 9

12:00 pm - 8:15 am

TYS

SCL

19h 15m

1 stop

8:40 pm - 9:12 am

SCL

TYS

13h 32m

1 stop

$1,005Delta

K, sept 30 - R, okt 9

7:27 am - 1:35 pm

TYS

SCL

30h 08m

2 stops

4:25 pm - 11:09 am

SCL

TYS

18h 44m

2 stops

$1,187LATAM Airlines

E, mai 25 - N, juuni 4

3:30 pm - 1:25 pm

TYS

SCL

21h 55m

3 stops

4:25 pm - 11:09 am

SCL

TYS

18h 44m

2 stops

$1,192LATAM Airlines

E, mai 25 - N, juuni 4

4:00 pm - 1:25 pm

TYS

SCL

20h 25m

3 stops

7:45 am - 11:46 pm

SCL

TYS

17h 01m

2 stops

$1,202LATAM Airlines

K, sept 30 - R, okt 9

3:30 pm - 6:55 am

TYS

SCL

15h 25m

2 stops

8:40 pm - 9:34 am

SCL

TYS

12h 54m

1 stop

$1,224LATAM Airlines

E, mai 25 - N, juuni 4

7:33 pm - 7:15 am

TYS

SCL

11h 42m

1 stop

8:40 pm - 11:09 am

SCL

TYS

14h 29m

1 stop

$1,247LATAM Airlines

E, mai 25 - N, juuni 4

12:00 pm - 1:25 pm

TYS

SCL

25h 25m

3 stops

7:45 am - 11:56 pm

SCL

TYS

16h 11m

2 stops

$1,252LATAM Airlines

E, mai 25 - N, juuni 4

4:00 pm - 7:15 am

TYS

SCL

15h 15m

1 stop

8:40 pm - 9:11 am

SCL

TYS

12h 31m

1 stop

$1,275LATAM Airlines

E, aug 24 - N, aug 27

4:00 pm - 1:25 pm

TYS

SCL

21h 25m

3 stops

7:50 am - 11:47 pm

SCL

TYS

15h 57m

2 stops

$1,280LATAM Airlines

E, aug 24 - N, aug 27

LATAM Airlines flights from Knoxville to Santiago

Our best LATAM Airlines deals on Knoxville to Santiago flight tickets

LATAM Airlines

Sep 30

TYS12:00 pmKnoxville McGhee Tyson

27h 35m

2 stops

SCL4:35 pmSantiago Arturo Merino Benitez

Oct 9

SCL8:40 pmSantiago Arturo Merino Benitez

13h 32m

1 stop

TYS9:12 amKnoxville McGhee Tyson

$997

LATAM Airlines

May 25

TYS7:27 amKnoxville McGhee Tyson

30h 08m

2 stops

SCL1:35 pmSantiago Arturo Merino Benitez

Jun 4

SCL4:25 pmSantiago Arturo Merino Benitez

18h 44m

2 stops

TYS11:09 amKnoxville McGhee Tyson

$1,187

LATAM Airlines

May 25

TYS3:30 pmKnoxville McGhee Tyson

21h 55m

3 stops

SCL1:25 pmSantiago Arturo Merino Benitez

Jun 4

SCL4:25 pmSantiago Arturo Merino Benitez

18h 44m

2 stops

TYS11:09 amKnoxville McGhee Tyson

$1,192

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

K 9/30

12:00 pm-4:35 pm

2 stops27h 35m

Santiago Arturo Merino Benitez

R 10/9

8:40 pm-9:12 am

1 stop13h 32m

$997

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

K 9/30

12:00 pm-8:15 am

1 stop19h 15m

Santiago Arturo Merino Benitez

R 10/9

8:40 pm-9:12 am

1 stop13h 32m

$1,005

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

E 5/25

7:27 am-1:35 pm

2 stops30h 08m

Santiago Arturo Merino Benitez

N 6/4

4:25 pm-11:09 am

2 stops18h 44m

$1,187

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

E 5/25

3:30 pm-1:25 pm

3 stops21h 55m

Santiago Arturo Merino Benitez

N 6/4

4:25 pm-11:09 am

2 stops18h 44m

$1,192

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

K 9/30

4:00 pm-1:25 pm

3 stops20h 25m

Santiago Arturo Merino Benitez

R 10/9

7:45 am-11:46 pm

2 stops17h 01m

$1,202

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

E 5/25

3:30 pm-6:55 am

2 stops15h 25m

Santiago Arturo Merino Benitez

N 6/4

8:40 pm-9:34 am

1 stop12h 54m

$1,224

Quickest round-trip

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

E 5/25

7:33 pm-7:15 am

1 stop11h 42m

Santiago Arturo Merino Benitez

N 6/4

8:40 pm-11:09 am

1 stop14h 29m

$1,247

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

E 5/25

12:00 pm-1:25 pm

3 stops25h 25m

Santiago Arturo Merino Benitez

N 6/4

7:45 am-11:56 pm

2 stops16h 11m

$1,252

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

E 8/24

4:00 pm-7:15 am

1 stop15h 15m

Santiago Arturo Merino Benitez

N 8/27

8:40 pm-9:11 am

1 stop12h 31m

$1,275

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

E 8/24

4:00 pm-1:25 pm

3 stops21h 25m

Santiago Arturo Merino Benitez

N 8/27

7:50 am-11:47 pm

2 stops15h 57m

$1,280

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

When to book flights from Knoxville to Santiago

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Santiago according to our flight data. Find out which month and days have the cheapest flights.

Estimated round-trip price

Cheap Knoxville to Santiago (TYS to SCL) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Santiago

Fastest flight time	19h 15m
Direct flights	None

The fastest flight from Knoxville to Santiago takes 19h 15m

There are no direct flights from Knoxville to Santiago. There are no popular flight routes from Knoxville to Santiago.

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Frequently asked questions about flying from Knoxville to Santiago

How far is Knoxville McGhee Tyson to Santiago Arturo Merino Benitez by plane?
A flight from Knoxville McGhee Tyson to Santiago Arturo Merino Benitez will travel around 4868.2 mi. A reasonable flight in good conditions will take 19h 15m.
When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Santiago Arturo Merino Benitez Airport?
Prices for flights from Knoxville McGhee Tyson Airport to Santiago Arturo Merino Benitez Airport are updated daily.
How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Santiago Arturo Merino Benitez Airport?
There is 1 operator available for flights from Knoxville McGhee Tyson Airport to Santiago Arturo Merino Benitez Airport as of April 2026.
How old do you have to be to fly from Knoxville McGhee Tyson Airport to Santiago Arturo Merino Benitez Airport?
The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Santiago Arturo Merino Benitez Airport.
What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?
The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.
What is the most popular airline from Knoxville to Santiago?
momondo data reveals that the most frequently booked airline on the route from Knoxville to Santiago is American Airlines, representing 100% of all bookings.

Best airlines flying from Knoxville to Santiago

Compare and see reviews for airlines that fly from Knoxville to Santiago with momondo

Airline	Rating	Free Cancellation	Price
American Airlines	PriceFrom $678	Free Cancellation	Rating 7.1 11,678 reviews		Search American Airlines flights

Frequently asked questions about flying from Knoxville to Santiago

How do I get Price Alerts for flights from Knoxville to Santiago?
Price Alerts will notify you by email when the price for flights to Santiago from Knoxville decreases. To activate this, select your desired travel dates and search for offers. While browsing through offers you’ll see the Price Alert widget toggle. Click it to turn on notifications.
How can I save money on flights from Knoxville to Santiago with momondo?
Plan your trips smart with the “Price Forecast” feature, which uses flight data to help you pick the best days to fly for the lowest fares. Our “Price Calendar” helps you get the most for your money by showing you when it’s most advantageous to fly. Curate your own travel experiences for less with “Explore”. Expert travel hacks to fuel your next adventure are a click away with “Discover” by momondo. Set up our “Price Alerts” to track fare changes and book when prices are at their lowest point.
How does momondo find its flight prices?
We show prices from over 700+ competitors with a single click. With options from airlines and OTAs from across our 30 international markets, we are able to show you a diverse range of deals to create your adventure.

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Santa Cruz

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Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Santiago?

It is quick and easy to find Knoxville to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Knoxville to Santiago with flexible booking policies on momondo?

All flight searches from Knoxville to Santiago on momondo can be filtered to show those which offer flexible booking policies.

How can momondo help me find flights from Knoxville to Santiago?

Once you have performed a search in the form on the page, momondo provides useful filters and insights. We can show you the cheapest days and times to fly as well as help filter your options to help you make an informed choice when booking flights to Santiago from Knoxville.

I’m not ready to book a flight from Knoxville to Santiago right now. Can momondo alert me if prices change?

Yes. momondo can track prices for Knoxville to Santiago flights and alert you when they change. Perform a search to set up the price alert. All that is required is a valid email address.