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Cheap flights from Knoxville to Brussels from $873

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Brussels departing on 9/22. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Knoxville to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
3:05 pm - 3:15 pm
TYS
-
BRU
18h 10m
2 stops
American Airlines Logo
12:00 pm - 9:24 pm
BRU
-
TYS
15h 24m
2 stops
$873American Airlines
Tue, Sep 22 - Tue, Nov 10
United Airlines Logo
1:35 pm - 1:15 pm
TYS
-
BRU
17h 40m
2 stops
United Airlines Logo
11:55 am - 7:17 pm
BRU
-
TYS
13h 22m
1 stop
$899United Airlines
Tue, Sep 22 - Tue, Nov 10
United Airlines Logo
1:59 pm - 9:00 am
TYS
-
BRU
13h 01m
1 stop
United Airlines Logo
10:10 am - 4:49 pm
BRU
-
TYS
12h 39m
1 stop
$903United Airlines
Tue, Sep 22 - Tue, Nov 10
Multiple Airlines Logo
9:45 am - 7:10 am
TYS
-
BRU
15h 25m
3 stops
Multiple Airlines Logo
10:00 am - 11:37 pm
BRU
-
TYS
19h 37m
2 stops
$918Multiple Airlines
Tue, Sep 22 - Tue, Nov 10
United Airlines Logo
7:19 pm - 8:00 pm
TYS
-
BRU
18h 41m
2 stops
United Airlines Logo
12:00 pm - 8:34 pm
BRU
-
TYS
14h 34m
1 stop
$993United Airlines
Tue, Jul 7 - Wed, Jul 15
United Airlines Logo
10:18 am - 9:00 am
TYS
-
BRU
16h 42m
1 stop
United Airlines Logo
10:15 am - 10:34 pm
BRU
-
TYS
18h 19m
1 stop
$997United Airlines
Tue, Jul 7 - Wed, Jul 15
United Airlines Logo
1:35 pm - 1:15 pm
TYS
-
BRU
17h 40m
2 stops
United Airlines Logo
12:00 pm - 8:44 pm
BRU
-
TYS
14h 44m
2 stops
$998United Airlines
Tue, Jul 7 - Wed, Jul 15
United Airlines Logo
5:45 am - 7:10 am
TYS
-
BRU
19h 25m
2 stops
United Airlines Logo
12:00 pm - 8:34 pm
BRU
-
TYS
14h 34m
1 stop
$1,000United Airlines
Tue, Jul 7 - Wed, Jul 15
United Airlines Logo
10:00 am - 7:45 am
TYS
-
BRU
15h 45m
2 stops
United Airlines Logo
12:00 pm - 10:34 pm
BRU
-
TYS
16h 34m
2 stops
$1,001United Airlines
Tue, Jul 7 - Wed, Jul 15
United Airlines Logo
1:35 pm - 8:00 pm
TYS
-
BRU
24h 25m
2 stops
United Airlines Logo
10:15 am - 4:58 pm
BRU
-
TYS
12h 43m
1 stop
$1,053United Airlines
Tue, Jul 21 - Mon, Aug 17

British Airways flights from Knoxville to Brussels Bruxelles-National Airport

Our best British Airways deals on Knoxville to Brussels Bruxelles-National Airport flight tickets
British Airways
Jun 6
TYS1:03 pmKnoxville McGhee Tyson
19h 17m
2 stops
BRU2:20 pmBrussels Bruxelles-National
Jun 12
BRU5:00 pmBrussels Bruxelles-National
31h 04m
2 stops
TYS6:04 pmKnoxville McGhee Tyson
$2,678
British Airways
Jun 6
TYS6:12 amKnoxville McGhee Tyson
26h 08m
2 stops
BRU2:20 pmBrussels Bruxelles-National
Jun 12
BRU5:00 pmBrussels Bruxelles-National
31h 04m
2 stops
TYS6:04 pmKnoxville McGhee Tyson
$2,869

United Airlines flights from Knoxville to Brussels Bruxelles-National Airport

Our best United Airlines deals on Knoxville to Brussels Bruxelles-National Airport flight tickets
United Airlines
Sep 22
TYS1:35 pmKnoxville McGhee Tyson
17h 40m
2 stops
BRU1:15 pmBrussels Bruxelles-National
Nov 10
BRU11:55 amBrussels Bruxelles-National
13h 22m
1 stop
TYS7:17 pmKnoxville McGhee Tyson
$899
United Airlines
Sep 22
TYS1:59 pmKnoxville McGhee Tyson
13h 01m
1 stop
BRU9:00 amBrussels Bruxelles-National
Nov 10
BRU10:10 amBrussels Bruxelles-National
12h 39m
1 stop
TYS4:49 pmKnoxville McGhee Tyson
$903
United Airlines
Jul 7
TYS7:19 pmKnoxville McGhee Tyson
18h 41m
2 stops
BRU8:00 pmBrussels Bruxelles-National
Jul 15
BRU12:00 pmBrussels Bruxelles-National
14h 34m
1 stop
TYS8:34 pmKnoxville McGhee Tyson
$993

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 23, 2026.
Use the filters below to find and compare flights from Knoxville to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 9/22

3:05 pm-3:15 pm

2 stops18h 10m

Brussels Bruxelles-National

Tue 11/10

12:00 pm-9:24 pm

2 stops15h 24m

$873

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 9/22

1:35 pm-1:15 pm

2 stops17h 40m

Brussels Bruxelles-National

Tue 11/10

11:55 am-7:17 pm

1 stop13h 22m

$899
Quickest round-trip

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 9/22

1:59 pm-9:00 am

1 stop13h 01m

Brussels Bruxelles-National

Tue 11/10

10:10 am-4:49 pm

1 stop12h 39m

$903

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 9/22

9:45 am-7:10 am

3 stops15h 25m

Brussels Bruxelles-National

Tue 11/10

10:00 am-11:37 pm

2 stops19h 37m

$918

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 7/7

7:19 pm-8:00 pm

2 stops18h 41m

Brussels Bruxelles-National

Wed 7/15

12:00 pm-8:34 pm

1 stop14h 34m

$993

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 7/7

10:18 am-9:00 am

1 stop16h 42m

Brussels Bruxelles-National

Wed 7/15

10:15 am-10:34 pm

1 stop18h 19m

$997

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 7/7

1:35 pm-1:15 pm

2 stops17h 40m

Brussels Bruxelles-National

Wed 7/15

12:00 pm-8:44 pm

2 stops14h 44m

$998

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 7/7

5:45 am-7:10 am

2 stops19h 25m

Brussels Bruxelles-National

Wed 7/15

12:00 pm-8:34 pm

1 stop14h 34m

$1,000

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 7/7

10:00 am-7:45 am

2 stops15h 45m

Brussels Bruxelles-National

Wed 7/15

12:00 pm-10:34 pm

2 stops16h 34m

$1,001

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 7/21

1:35 pm-8:00 pm

2 stops24h 25m

Brussels Bruxelles-National

Mon 8/17

10:15 am-4:58 pm

1 stop12h 43m

$1,053

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Brussels from

How to get the cheapest flight ticket from Knoxville to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Brussels Bruxelles-National Airport?

What is the cheapest month to fly to Brussels Bruxelles-National Airport?

The cheapest month to fly to Brussels Bruxelles-National Airport from Knoxville is in January. Flight prices, which tend to average around $0, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of January, then book flights to Brussels Bruxelles-National Airport from Knoxville during October instead. Flights to Brussels Bruxelles-National Airport in October, while not as cheap as those in January, still average around $702.

Can stopping save me money on Knoxville to Brussels Bruxelles-National Airport flights?

You could potentially save up to 1% on your flight if you consider stops on a Knoxville to Brussels Bruxelles-National Airport flight.

When to book flights from Knoxville to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Brussels Bruxelles-National Airport (TYS to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Brussels Bruxelles-National Airport

Fastest flight time

16h 40m

Direct flights

None
The fastest flight from Knoxville to Brussels Bruxelles-National Airport takes 16h 40m
There are no direct flights from Knoxville to Brussels Bruxelles-National Airport. There are no popular flight routes from Knoxville to Brussels Bruxelles-National Airport.
Search flight deals

Frequently asked questions about flying from Knoxville to Brussels Bruxelles-National Airport

  • How far is Knoxville McGhee Tyson to Brussels Bruxelles-National by plane?

    Knoxville McGhee Tyson and Brussels Bruxelles-National are 4278.7 mi apart from one another. In terms of flight time, this usually takes a little over 16h 40m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The necessary travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Brussels Bruxelles-National Airport?

Best airlines flying from Knoxville to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Knoxville to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $603Free CancellationRating
7.4
9,751 reviews
Search United Airlines flights

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Bruges
Ghent
Leuven
Charleroi
Zaventem
Mons
Hasselt
Durbuy
Genk
Dinant
Namur
Waterloo
Aalst
Mechelen
Knokke-Heist
Spa
Francorchamps
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Brussels?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Brussels. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Brussels with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Brussels from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Brussels?

momondo helps you find the best flight between Knoxville and Brussels by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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