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Cheap flights from Knoxville to Brussels from $527

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Brussels departing on 10/24. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Brussels

Cheap round-trip flights

Scandinavian Airlines Logo
3:48 pm - 10:40 amTYS-BRU
36h 52m2 stops
Scandinavian Airlines Logo
8:30 pm - 11:07 pmBRU-TYS
31h 37m2 stops
$527Scandinavian Airlines
Find Deal
Fri, Oct 24 - Fri, Oct 31
Scandinavian Airlines Logo
3:48 pm - 3:20 pmTYS-BRU
17h 32m2 stops
Scandinavian Airlines Logo
3:10 pm - 11:46 pmBRU-TYS
37h 36m2 stops
$647Scandinavian Airlines
Find Deal
Wed, Oct 22 - Wed, Oct 29
United Airlines Logo
9:50 am - 7:50 amTYS-BRU
16h 00m2 stops
United Airlines Logo
11:55 am - 11:59 pmBRU-TYS
18h 04m1 stop
$657United Airlines
Find Deal
Wed, Nov 12 - Sun, Nov 16
United Airlines Logo
2:16 pm - 7:15 amTYS-BRU
10h 59m1 stop
United Airlines Logo
10:10 am - 10:55 pmBRU-TYS
17h 45m1 stop
$687United Airlines
Find Deal
Wed, Oct 22 - Wed, Oct 29
United Airlines Logo
8:26 am - 8:55 amTYS-BRU
18h 29m1 stop
United Airlines Logo
10:10 am - 5:08 pmBRU-TYS
12h 58m1 stop
$707United Airlines
Find Deal
Sun, Nov 9 - Sun, Nov 16
United Airlines Logo
8:50 am - 9:00 amTYS-BRU
18h 10m1 stop
United Airlines Logo
10:00 am - 5:08 pmBRU-TYS
36h 08m2 stops
$714United Airlines
Find Deal
Fri, Oct 24 - Fri, Oct 31
Multiple Airlines Logo
9:55 am - 8:05 amTYS-BRU
16h 10m3 stops
Multiple Airlines Logo
10:00 am - 11:59 pmBRU-TYS
18h 59m2 stops
$793Multiple Airlines
Find Deal
Wed, Oct 22 - Wed, Oct 29
Multiple Airlines Logo
5:37 pm - 7:10 pmTYS-BRU
19h 33m2 stops
Multiple Airlines Logo
9:50 am - 10:09 pmBRU-TYS
17h 19m3 stops
$1,005Multiple Airlines
Find Deal
Fri, Oct 24 - Fri, Oct 31
Air Canada Logo
9:55 am - 8:05 amTYS-BRU
16h 10m3 stops
Air Canada Logo
7:00 am - 8:20 pmBRU-TYS
18h 20m3 stops
$1,351Air Canada
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Wed, Oct 22 - Wed, Oct 29
Air Canada Logo
9:55 am - 8:05 amTYS-BRU
16h 10m3 stops
Air Canada Logo
7:00 am - 8:20 pmBRU-TYS
18h 20m3 stops
$2,136Air Canada
Find Deal
Fri, Oct 24 - Fri, Oct 31

United Airlines flights from Knoxville to Brussels Bruxelles-National Airport

Our best United Airlines deals on Knoxville to Brussels Bruxelles-National Airport flight tickets
United Airlines
Nov 12
TYS9:50 amKnoxville McGhee Tyson
16h 00m
2 stops
BRU7:50 amBrussels Bruxelles-National
Nov 16
BRU11:55 amBrussels Bruxelles-National
18h 04m
1 stop
TYS11:59 pmKnoxville McGhee Tyson
$657
Find similar
United Airlines
Oct 22
TYS2:16 pmKnoxville McGhee Tyson
10h 59m
1 stop
BRU7:15 amBrussels Bruxelles-National
Oct 29
BRU10:10 amBrussels Bruxelles-National
17h 45m
1 stop
TYS10:55 pmKnoxville McGhee Tyson
$687
Find similar
United Airlines
Nov 9
TYS8:26 amKnoxville McGhee Tyson
18h 29m
1 stop
BRU8:55 amBrussels Bruxelles-National
Nov 16
BRU10:10 amBrussels Bruxelles-National
12h 58m
1 stop
TYS5:08 pmKnoxville McGhee Tyson
$707
Find similar

Scandinavian Airlines flights from Knoxville to Brussels Bruxelles-National Airport

Our best Scandinavian Airlines deals on Knoxville to Brussels Bruxelles-National Airport flight tickets
Scandinavian Airlines
Oct 24
TYS3:48 pmKnoxville McGhee Tyson
36h 52m
2 stops
BRU10:40 amBrussels Bruxelles-National
Oct 31
BRU8:30 pmBrussels Bruxelles-National
31h 37m
2 stops
TYS11:07 pmKnoxville McGhee Tyson
$527
Find similar
Scandinavian Airlines
Oct 22
TYS3:48 pmKnoxville McGhee Tyson
17h 32m
2 stops
BRU3:20 pmBrussels Bruxelles-National
Oct 29
BRU3:10 pmBrussels Bruxelles-National
37h 36m
2 stops
TYS11:46 pmKnoxville McGhee Tyson
$647
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 26, 2025.
Use the filters below to find and compare flights from Knoxville to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Fri 10/24

3:48 pm-10:40 am

2 stops36h 52m

Brussels Bruxelles-National

Fri 10/31

8:30 pm-11:07 pm

2 stops31h 37m

$527

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Wed 10/22

3:48 pm-3:20 pm

2 stops17h 32m

Brussels Bruxelles-National

Wed 10/29

3:10 pm-11:46 pm

2 stops37h 36m

$647

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Wed 11/12

9:50 am-7:50 am

2 stops16h 00m

Brussels Bruxelles-National

Sun 11/16

11:55 am-11:59 pm

1 stop18h 04m

$657

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Wed 10/22

2:16 pm-7:15 am

1 stop10h 59m

Brussels Bruxelles-National

Wed 10/29

10:10 am-10:55 pm

1 stop17h 45m

$687

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Sun 11/9

8:26 am-8:55 am

1 stop18h 29m

Brussels Bruxelles-National

Sun 11/16

10:10 am-5:08 pm

1 stop12h 58m

$707

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Fri 10/24

8:50 am-9:00 am

1 stop18h 10m

Brussels Bruxelles-National

Fri 10/31

10:00 am-5:08 pm

2 stops36h 08m

$714

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Wed 10/22

9:55 am-8:05 am

3 stops16h 10m

Brussels Bruxelles-National

Wed 10/29

10:00 am-11:59 pm

2 stops18h 59m

$793

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Fri 10/24

5:37 pm-7:10 pm

2 stops19h 33m

Brussels Bruxelles-National

Fri 10/31

9:50 am-10:09 pm

3 stops17h 19m

$1,005

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Wed 10/22

9:55 am-8:05 am

3 stops16h 10m

Brussels Bruxelles-National

Wed 10/29

7:00 am-8:20 pm

3 stops18h 20m

$1,351

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Fri 10/24

9:55 am-8:05 am

3 stops16h 10m

Brussels Bruxelles-National

Fri 10/31

7:00 am-8:20 pm

3 stops18h 20m

$2,136

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Brussels from

How to get the cheapest flight ticket from Knoxville to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Brussels Bruxelles-National Airport?

The cheapest day to depart from Knoxville to Brussels Bruxelles-National Airport is on a Tuesday. Travelers who choose to depart for Brussels Bruxelles-National Airport on a Tuesday will often find tickets for as low as $912. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Knoxville to Brussels Bruxelles-National Airport for around $1,355.

What is the cheapest time of day to depart on your flight to Brussels Bruxelles-National Airport?

Our most recent data shows that the best time of day to fly to Brussels Bruxelles-National Airport is in the afternoon. Flights from Knoxville to Brussels Bruxelles-National Airport during this time can be as low as $949. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $1,105 on average. Flights to Brussels Bruxelles-National Airport from Knoxville at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

When to book flights from Knoxville to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Brussels Bruxelles-National Airport (TYS to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Brussels Bruxelles-National Airport

Direct flights

None
There are no direct flights from Knoxville to Brussels Bruxelles-National Airport. There are no popular flight routes from Knoxville to Brussels Bruxelles-National Airport.
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  • How far is Knoxville McGhee Tyson to Brussels Bruxelles-National by plane?

    Knoxville McGhee Tyson and Brussels Bruxelles-National are 4278.7 mi apart from one another. In terms of flight time, this usually takes a little over 10h 59m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The necessary travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Brussels Bruxelles-National Airport?

Best airlines flying from Knoxville to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Knoxville to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $676Free CancellationRating
7.4
8,928 reviews
Search United Airlines flights

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Bruges
Ghent
Leuven
Charleroi
Hasselt
Spa
Namur
Aalst
Dinant
Mons
Zaventem
Waterloo
Genk
Mechelen
Francorchamps
Knokke-Heist
Tournai
Durbuy
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Brussels?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Brussels. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Brussels with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Brussels from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Brussels?

momondo helps you find the best flight between Knoxville and Brussels by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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