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Cheap flights from Knoxville to Brussels from $1,138

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Brussels departing on 3/27. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Cheap round-trip flights

Enter your travel dates to find the best prices.
Scandinavian Airlines Logo
2:30 pm - 2:30 pmTYS-BRU
19h 00m2 stops
Scandinavian Airlines Logo
10:20 am - 11:44 pmBRU-TYS
19h 24m2 stops
$1,138Scandinavian Airlines
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Fri, Mar 27 - Tue, Mar 31
United Airlines Logo
10:50 am - 1:15 pmTYS-BRU
20h 25m2 stops
United Airlines Logo
1:50 pm - 10:39 pmBRU-TYS
38h 49m2 stops
$1,157United Airlines
Find Deal
Sun, Dec 14 - Mon, Dec 29
Lufthansa Logo
2:30 pm - 7:15 amTYS-BRU
11h 45m1 stop
Lufthansa Logo
10:15 am - 5:28 pmBRU-TYS
13h 13m1 stop
$1,171Lufthansa
Find Deal
Fri, Mar 27 - Tue, Mar 31
Multiple Airlines Logo
2:30 pm - 11:10 amTYS-BRU
14h 40m2 stops
Multiple Airlines Logo
11:55 am - 7:51 pmBRU-TYS
13h 56m1 stop
$1,232Multiple Airlines
Find Deal
Sun, Dec 14 - Mon, Dec 29
Multiple Airlines Logo
6:00 am - 9:05 amTYS-BRU
21h 05m2 stops
Multiple Airlines Logo
11:50 am - 12:00 pmBRU-TYS
30h 10m3 stops
$1,358Multiple Airlines
Find Deal
Sun, Dec 14 - Mon, Dec 29
Multiple Airlines Logo
5:23 pm - 11:25 pmTYS-BRU
24h 02m3 stops
Multiple Airlines Logo
11:50 am - 12:00 pmBRU-TYS
30h 10m3 stops
$1,398Multiple Airlines
Find Deal
Sun, Dec 14 - Mon, Dec 29
Lufthansa Logo
7:25 pm - 7:15 amTYS-BRU
29h 50m1 stop
Lufthansa Logo
11:55 am - 11:59 pmBRU-TYS
18h 04m1 stop
$1,486Lufthansa
Find Deal
Sun, Dec 14 - Mon, Dec 29
United Airlines Logo
5:45 am - 7:15 amTYS-BRU
19h 30m1 stop
United Airlines Logo
11:55 am - 10:17 amBRU-TYS
28h 22m2 stops
$1,515United Airlines
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Fri, Dec 26 - Fri, Jan 2
United Airlines Logo
6:45 am - 7:50 amTYS-BRU
19h 05m2 stops
United Airlines Logo
11:55 am - 11:59 pmBRU-TYS
18h 04m1 stop
$1,541United Airlines
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Sun, Dec 28 - Sun, Jan 4
United Airlines Logo
6:45 am - 7:50 amTYS-BRU
19h 05m2 stops
United Airlines Logo
11:55 am - 11:11 amBRU-TYS
29h 16m2 stops
$1,546United Airlines
Find Deal
Sun, Dec 28 - Sun, Jan 4

Lufthansa flights from Knoxville to Brussels Bruxelles-National Airport

Our best Lufthansa deals on Knoxville to Brussels Bruxelles-National Airport flight tickets
Lufthansa
Mar 27
TYS2:30 pmKnoxville McGhee Tyson
11h 45m
1 stop
BRU7:15 amBrussels Bruxelles-National
Mar 31
BRU10:15 amBrussels Bruxelles-National
13h 13m
1 stop
TYS5:28 pmKnoxville McGhee Tyson
$1,171
Find similar
Lufthansa
Dec 14
TYS7:25 pmKnoxville McGhee Tyson
29h 50m
1 stop
BRU7:15 amBrussels Bruxelles-National
Dec 29
BRU11:55 amBrussels Bruxelles-National
18h 04m
1 stop
TYS11:59 pmKnoxville McGhee Tyson
$1,486
Find similar

United Airlines flights from Knoxville to Brussels Bruxelles-National Airport

Our best United Airlines deals on Knoxville to Brussels Bruxelles-National Airport flight tickets
United Airlines
Dec 14
TYS10:50 amKnoxville McGhee Tyson
20h 25m
2 stops
BRU1:15 pmBrussels Bruxelles-National
Dec 29
BRU1:50 pmBrussels Bruxelles-National
38h 49m
2 stops
TYS10:39 pmKnoxville McGhee Tyson
$1,157
Find similar
United Airlines
Dec 26
TYS5:45 amKnoxville McGhee Tyson
19h 30m
1 stop
BRU7:15 amBrussels Bruxelles-National
Jan 2
BRU11:55 amBrussels Bruxelles-National
28h 22m
2 stops
TYS10:17 amKnoxville McGhee Tyson
$1,515
Find similar
United Airlines
Dec 28
TYS6:45 amKnoxville McGhee Tyson
19h 05m
2 stops
BRU7:50 amBrussels Bruxelles-National
Jan 4
BRU11:55 amBrussels Bruxelles-National
18h 04m
1 stop
TYS11:59 pmKnoxville McGhee Tyson
$1,541
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Knoxville to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Fri 3/27

2:30 pm-2:30 pm

2 stops19h 00m

Brussels Bruxelles-National

Tue 3/31

10:20 am-11:44 pm

2 stops19h 24m

$1,138

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Sun 12/14

10:50 am-1:15 pm

2 stops20h 25m

Brussels Bruxelles-National

Mon 12/29

1:50 pm-10:39 pm

2 stops38h 49m

$1,157

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Fri 3/27

2:30 pm-7:15 am

1 stop11h 45m

Brussels Bruxelles-National

Tue 3/31

10:15 am-5:28 pm

1 stop13h 13m

$1,171

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Sun 12/14

2:30 pm-11:10 am

2 stops14h 40m

Brussels Bruxelles-National

Mon 12/29

11:55 am-7:51 pm

1 stop13h 56m

$1,232

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Sun 12/14

6:00 am-9:05 am

2 stops21h 05m

Brussels Bruxelles-National

Mon 12/29

11:50 am-12:00 pm

3 stops30h 10m

$1,358

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Sun 12/14

5:23 pm-11:25 pm

3 stops24h 02m

Brussels Bruxelles-National

Mon 12/29

11:50 am-12:00 pm

3 stops30h 10m

$1,398

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Sun 12/14

7:25 pm-7:15 am

1 stop29h 50m

Brussels Bruxelles-National

Mon 12/29

11:55 am-11:59 pm

1 stop18h 04m

$1,486

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Fri 12/26

5:45 am-7:15 am

1 stop19h 30m

Brussels Bruxelles-National

Fri 1/2

11:55 am-10:17 am

2 stops28h 22m

$1,515

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Sun 12/28

6:45 am-7:50 am

2 stops19h 05m

Brussels Bruxelles-National

Sun 1/4

11:55 am-11:59 pm

1 stop18h 04m

$1,541

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Sun 12/28

6:45 am-7:50 am

2 stops19h 05m

Brussels Bruxelles-National

Sun 1/4

11:55 am-11:11 am

2 stops29h 16m

$1,546

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Brussels from

How to get the cheapest flight ticket from Knoxville to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Brussels Bruxelles-National Airport?

The cheapest day to depart from Knoxville to Brussels Bruxelles-National Airport is on a Tuesday. Travelers who choose to depart for Brussels Bruxelles-National Airport on a Tuesday will often find tickets for as low as $912. When flying out on a Thursday, the most expensive travel day of the week, you can expect to see flight prices from Knoxville to Brussels Bruxelles-National Airport for around $1,355.

What is the cheapest time of day to depart on your flight to Brussels Bruxelles-National Airport?

Our most recent data shows that the best time of day to fly to Brussels Bruxelles-National Airport is in the afternoon. Flights from Knoxville to Brussels Bruxelles-National Airport during this time can be as low as $949. If you have a flexible travel schedule, then try to avoid flying at noon when prices are $1,105 on average. Flights to Brussels Bruxelles-National Airport from Knoxville at noon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Can stopping save me money on Knoxville to Brussels Bruxelles-National Airport flights?

You could potentially save up to 15% on your flight if you consider stops on a Knoxville to Brussels Bruxelles-National Airport flight.

When to book flights from Knoxville to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Brussels Bruxelles-National Airport (TYS to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Brussels Bruxelles-National Airport

Direct flights

None
There are no direct flights from Knoxville to Brussels Bruxelles-National Airport. There are no popular flight routes from Knoxville to Brussels Bruxelles-National Airport.
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  • How far is Knoxville McGhee Tyson to Brussels Bruxelles-National by plane?

    Knoxville McGhee Tyson and Brussels Bruxelles-National are 4278.7 mi apart from one another. In terms of flight time, this usually takes a little over 11h 45m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The necessary travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Brussels Bruxelles-National Airport?

Best airlines flying from Knoxville to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Knoxville to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $603Free CancellationRating
7.4
9,017 reviews
Search United Airlines flights

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Ghent
Bruges
Leuven
Charleroi
Hasselt
Spa
Zaventem
Namur
Dinant
Mons
Genk
Waterloo
Mechelen
Durbuy
Francorchamps
Knokke-Heist
Aalst
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Brussels?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Brussels. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Brussels with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Brussels from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Brussels?

momondo helps you find the best flight between Knoxville and Brussels by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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