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Cheap flights from Knoxville to Brussels from $872

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Knoxville to Brussels departing on 5/4. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Knoxville to Brussels

Cheap round-trip flights

Enter your travel dates to find the best prices.
United Airlines Logo
9:50 am - 7:15 am
TYS
-
BRU
15h 25m
1 stop
United Airlines Logo
10:15 am - 8:45 pm
BRU
-
TYS
16h 30m
1 stop
$872United Airlines
Mon, May 4 - Sun, May 10
Multiple Airlines Logo
7:00 am - 7:50 am
TYS
-
BRU
18h 50m
2 stops
Multiple Airlines Logo
9:55 am - 8:45 pm
BRU
-
TYS
16h 50m
2 stops
$884Multiple Airlines
Mon, May 4 - Sun, May 10
Multiple Airlines Logo
7:00 am - 7:50 am
TYS
-
BRU
18h 50m
2 stops
Multiple Airlines Logo
2:25 pm - 10:49 am
BRU
-
TYS
26h 24m
3 stops
$895Multiple Airlines
Mon, May 4 - Sun, May 10
United Airlines Logo
10:00 am - 7:15 am
TYS
-
BRU
15h 15m
1 stop
United Airlines Logo
10:15 am - 4:59 pm
BRU
-
TYS
12h 44m
1 stop
$1,034United Airlines
Tue, Sep 1 - Sun, Sep 13
United Airlines Logo
10:49 am - 7:45 am
TYS
-
BRU
14h 56m
2 stops
United Airlines Logo
10:15 am - 5:12 pm
BRU
-
TYS
12h 57m
1 stop
$1,040United Airlines
Fri, May 15 - Fri, May 22
United Airlines Logo
7:00 am - 7:45 am
TYS
-
BRU
18h 45m
2 stops
United Airlines Logo
11:10 am - 12:30 am
BRU
-
TYS
19h 20m
2 stops
$1,045United Airlines
Fri, May 15 - Fri, May 22
United Airlines Logo
7:05 am - 5:30 pm
TYS
-
BRU
28h 25m
2 stops
United Airlines Logo
10:45 am - 11:54 pm
BRU
-
TYS
19h 09m
1 stop
$1,060United Airlines
Sun, May 17 - Sun, May 24
United Airlines Logo
7:05 am - 5:30 pm
TYS
-
BRU
28h 25m
2 stops
United Airlines Logo
9:55 am - 8:56 pm
BRU
-
TYS
17h 01m
2 stops
$1,064United Airlines
Sun, May 17 - Sun, May 24
United Airlines Logo
7:00 am - 9:00 am
TYS
-
BRU
20h 00m
1 stop
United Airlines Logo
9:40 am - 2:27 pm
BRU
-
TYS
34h 47m
2 stops
$1,087United Airlines
Tue, May 19 - Wed, Jun 17
United Airlines Logo
7:00 am - 9:00 am
TYS
-
BRU
20h 00m
1 stop
United Airlines Logo
12:00 pm - 8:34 pm
BRU
-
TYS
14h 34m
1 stop
$1,107United Airlines
Tue, May 19 - Wed, Jun 17

Lufthansa flights from Knoxville to Brussels Bruxelles-National Airport

Our best Lufthansa deals on Knoxville to Brussels Bruxelles-National Airport flight tickets
Lufthansa
Apr 8
TYS1:52 pmKnoxville McGhee Tyson
16h 53m
2 stops
BRU12:45 pmBrussels Bruxelles-National
Apr 22
BRU7:00 amBrussels Bruxelles-National
22h 08m
2 stops
TYS11:08 pmKnoxville McGhee Tyson
$938
Lufthansa
Apr 8
TYS5:53 pmKnoxville McGhee Tyson
17h 37m
2 stops
BRU5:30 pmBrussels Bruxelles-National
Apr 22
BRU8:30 amBrussels Bruxelles-National
20h 38m
2 stops
TYS11:08 pmKnoxville McGhee Tyson
$939
Lufthansa
Jul 21
TYS10:00 amKnoxville McGhee Tyson
15h 45m
2 stops
BRU7:45 amBrussels Bruxelles-National
Aug 17
BRU12:45 pmBrussels Bruxelles-National
17h 12m
2 stops
TYS11:57 pmKnoxville McGhee Tyson
$1,155

KLM flights from Knoxville to Brussels Bruxelles-National Airport

Our best KLM deals on Knoxville to Brussels Bruxelles-National Airport flight tickets
KLM
May 17
TYS7:33 pmKnoxville McGhee Tyson
30h 07m
1 stop
BRU7:40 amBrussels Bruxelles-National
May 24
BRU9:45 amBrussels Bruxelles-National
15h 03m
1 stop
TYS6:48 pmKnoxville McGhee Tyson
$1,200
KLM
Jul 21
TYS1:59 pmKnoxville McGhee Tyson
11h 41m
1 stop
BRU7:40 amBrussels Bruxelles-National
Aug 17
BRU9:45 amBrussels Bruxelles-National
16h 57m
1 stop
TYS8:42 pmKnoxville McGhee Tyson
$1,206
KLM
Jun 21
TYS10:26 amKnoxville McGhee Tyson
15h 14m
1 stop
BRU7:40 amBrussels Bruxelles-National
Jun 28
BRU9:45 amBrussels Bruxelles-National
20h 09m
1 stop
TYS11:54 pmKnoxville McGhee Tyson
$1,304

momondo Fare Finder

 
Customize your flight search to find flights from Knoxville to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated April 5, 2026.
Use the filters below to find and compare flights from Knoxville to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Mon 5/4

9:50 am-7:15 am

1 stop15h 25m

Brussels Bruxelles-National

Sun 5/10

10:15 am-8:45 pm

1 stop16h 30m

$872

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Mon 5/4

7:00 am-7:50 am

2 stops18h 50m

Brussels Bruxelles-National

Sun 5/10

9:55 am-8:45 pm

2 stops16h 50m

$884

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Mon 5/4

7:00 am-7:50 am

2 stops18h 50m

Brussels Bruxelles-National

Sun 5/10

2:25 pm-10:49 am

3 stops26h 24m

$895

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 9/1

10:00 am-7:15 am

1 stop15h 15m

Brussels Bruxelles-National

Sun 9/13

10:15 am-4:59 pm

1 stop12h 44m

$1,034
Quickest round-trip

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Fri 5/15

10:49 am-7:45 am

2 stops14h 56m

Brussels Bruxelles-National

Fri 5/22

10:15 am-5:12 pm

1 stop12h 57m

$1,040

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Fri 5/15

7:00 am-7:45 am

2 stops18h 45m

Brussels Bruxelles-National

Fri 5/22

11:10 am-12:30 am

2 stops19h 20m

$1,045

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Sun 5/17

7:05 am-5:30 pm

2 stops28h 25m

Brussels Bruxelles-National

Sun 5/24

10:45 am-11:54 pm

1 stop19h 09m

$1,060

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Sun 5/17

7:05 am-5:30 pm

2 stops28h 25m

Brussels Bruxelles-National

Sun 5/24

9:55 am-8:56 pm

2 stops17h 01m

$1,064

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 5/19

7:00 am-9:00 am

1 stop20h 00m

Brussels Bruxelles-National

Wed 6/17

9:40 am-2:27 pm

2 stops34h 47m

$1,087

KnoxvilleBrussels

TYS - BRU

TYSBRU

Knoxville McGhee Tyson

Tue 5/19

7:00 am-9:00 am

1 stop20h 00m

Brussels Bruxelles-National

Wed 6/17

12:00 pm-8:34 pm

1 stop14h 34m

$1,107

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Brussels from

How to get the cheapest flight ticket from Knoxville to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Knoxville and Brussels Bruxelles-National Airport?

Can stopping save me money on Knoxville to Brussels Bruxelles-National Airport flights?

You could potentially save up to 1% on your flight if you consider stops on a Knoxville to Brussels Bruxelles-National Airport flight.

When to book flights from Knoxville to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Knoxville to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Knoxville to Brussels Bruxelles-National Airport (TYS to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Knoxville to Brussels Bruxelles-National Airport

Fastest flight time

15h 14m

Direct flights

None
The fastest flight from Knoxville to Brussels Bruxelles-National Airport takes 15h 14m
There are no direct flights from Knoxville to Brussels Bruxelles-National Airport. There are no popular flight routes from Knoxville to Brussels Bruxelles-National Airport.
Search flight deals

Frequently asked questions about flying from Knoxville to Brussels Bruxelles-National Airport

  • How far is Knoxville McGhee Tyson to Brussels Bruxelles-National by plane?

    Knoxville McGhee Tyson and Brussels Bruxelles-National are 4278.7 mi apart from one another. In terms of flight time, this usually takes a little over 15h 14m.

  • When did momondo last update prices for flights from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport?

    Prices for flights from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport were last updated today.

  • How many operators does momondo search for flights from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Knoxville McGhee Tyson Airport to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The necessary travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your travel plans and individual circumstances. Generally, you should have various documents, such as a national ID card or driver's license and a passport that is valid for six months beyond your scheduled arrival date. We recommend seeking advice from your airline or a trusted third party, such as IATA.

  • What is the most popular airline from Knoxville to Brussels Bruxelles-National Airport?

Best airlines flying from Knoxville to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Knoxville to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
United AirlinesPriceFrom $603Free CancellationRating
7.4
9,545 reviews
Search United Airlines flights

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Ghent
Bruges
Leuven
Charleroi
Zaventem
Hasselt
Namur
Genk
Waterloo
Dinant
Durbuy
Mons
Aalst
Knokke-Heist
Spa
Mechelen
Francorchamps
Tournai
Oostkamp
Halle

Why use momondo?

Why should I use momondo to find a flight deal from Knoxville to Brussels?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Knoxville to Brussels. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Knoxville to Brussels with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Brussels from Knoxville with this policy.

How can momondo help me find flights from Knoxville to Brussels?

momondo helps you find the best flight between Knoxville and Brussels by providing filters to narrow your choice of flights to those matching your criteria. You can select flights based on numerous factors such as price, departure and landing times, airport and airline.

I’m not ready to book a flight from Knoxville to Brussels right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Knoxville to Brussels flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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