Cheap flights from Chicago O'Hare Intl Airport to Brussels from $257

The cheapest month to fly to Brussels Bruxelles-National Airport from Chicago O'Hare Intl Airport is in October. Flight prices, which tend to average around $673, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of October, then book flights to Brussels Bruxelles-National Airport from Chicago O'Hare Intl Airport during November instead. Flights to Brussels Bruxelles-National Airport in November, while not as cheap as those in October, still average around $674.

The cheapest day to depart from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport is on a Tuesday. Travelers who choose to depart for Brussels Bruxelles-National Airport on a Tuesday will often find tickets for as low as $1,148. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport for around $1,406.

Our most recent data shows that the best time of day to fly to Brussels Bruxelles-National Airport is in the evening. Flights from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport during this time can be as low as $1,234. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $1,303 on average. Flights to Brussels Bruxelles-National Airport from Chicago O'Hare Intl Airport in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

Fly from Chicago O'Hare Intl to Brussels Bruxelles-National for the best Chicago O'Hare Intl - Brussels Bruxelles-National flight prices

You are more likely to see cheaper flights to Brussels Bruxelles-National Airport from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Brussels Bruxelles-National Airport for around $891 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Brussels Bruxelles-National Airport from Chicago O'Hare Intl Airport for as low as $591 on momondo.

There are 3 cabin classes available to choose from on Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

You could potentially save up to 14% on your flight if you consider stops on a Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport flight.

Aer Lingus and Turkish Airlines are the most popular carriers operating from Chicago O'Hare Intl to Brussels Bruxelles-National

Scandinavian Airlines, United Airlines and Icelandair are the top three most popular airlines that fly to Brussels Bruxelles-National Airport from Chicago O'Hare Intl Airport according to our data. Scandinavian Airlines is the first choice among our users, with 33% of people opting to fly with this airline when traveling to Brussels Bruxelles-National Airport. Keep in mind that there are 7 different airlines that fly to Brussels Bruxelles-National Airport on a routine basis, so you have a few additional options to choose from.

Copenhagen (CPH) was the most common stop: 29% of momondo users choosing 1-stop flights on this route connected there.

Flights via Dublin (DUB) offer the lowest average round-trip price of $656.

Flights connecting via Reykjavik (KEF) have the shortest average one-way travel time: 10h 29m.

Reykjavik (KEF) has the shortest average layover time for this route: 1h 04m.

5 flights are operational daily from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport as of September 2026. The most popular departure time for this route is 6:00PM, with 100% of flights per day taking off in the evening.

As of September 2026, there are 35 flights per week flying from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport. The most common day of the week flights depart is Mon, with 14% of flights taking off on this day.