Latest deals
Insights
When to book
FAQs
Reviews
Price Alerts

Cheap flights from Chicago O'Hare Intl Airport to Brussels from $246

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Chicago O'Hare Intl Airport to Brussels departing on 11/16. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Chicago O'Hare Intl Airport to Brussels (ORD-BRU)

Cheap round-trip flights

Icelandair Logo
6:30 pm - 11:55 amORD-BRU
10h 25m1 stop
Icelandair Logo
12:50 pm - 5:20 pmBRU-ORD
11h 30m1 stop
$423Icelandair
Find Deal
Wed, Jan 28 - Fri, Feb 6
Icelandair Logo
7:25 pm - 12:50 pmORD-BRU
10h 25m1 stop
Icelandair Logo
1:50 pm - 6:15 pmBRU-ORD
11h 25m1 stop
$425Icelandair
Find Deal
Sun, Oct 5 - Thu, Oct 16
Scandinavian Airlines Logo
7:20 pm - 10:50 amORD-BRU
32h 30m2 stops
Scandinavian Airlines Logo
11:30 am - 4:45 pmBRU-ORD
36h 15m2 stops
$428Scandinavian Airlines
Find Deal
Wed, Nov 5 - Tue, Dec 9
Scandinavian Airlines Logo
7:20 pm - 10:50 amORD-BRU
32h 30m2 stops
Scandinavian Airlines Logo
3:10 pm - 4:45 pmBRU-ORD
32h 35m1 stop
$432Scandinavian Airlines
Find Deal
Wed, Nov 5 - Tue, Dec 9
Scandinavian Airlines Logo
7:20 pm - 11:55 amORD-BRU
33h 35m2 stops
Scandinavian Airlines Logo
7:45 pm - 4:45 pmBRU-ORD
28h 00m2 stops
$433Scandinavian Airlines
Find Deal
Fri, Nov 28 - Sun, Dec 7
Scandinavian Airlines Logo
7:20 pm - 7:50 pmORD-BRU
17h 30m1 stop
Scandinavian Airlines Logo
3:10 pm - 4:45 pmBRU-ORD
32h 35m1 stop
$435Scandinavian Airlines
Find Deal
Wed, Nov 5 - Tue, Dec 9
Scandinavian Airlines Logo
7:20 pm - 2:30 pmORD-BRU
12h 10m1 stop
Scandinavian Airlines Logo
10:20 am - 4:45 pmBRU-ORD
13h 25m1 stop
$436Scandinavian Airlines
Find Deal
Wed, Jan 28 - Mon, Feb 2
Scandinavian Airlines Logo
7:20 pm - 7:50 pmORD-BRU
17h 30m1 stop
Scandinavian Airlines Logo
10:20 am - 4:45 pmBRU-ORD
13h 25m1 stop
$439Scandinavian Airlines
Find Deal
Wed, Nov 26 - Thu, Dec 4
Scandinavian Airlines Logo
7:20 pm - 10:50 amORD-BRU
32h 30m2 stops
Scandinavian Airlines Logo
7:20 pm - 4:45 pmBRU-ORD
28h 25m2 stops
$441Scandinavian Airlines
Find Deal
Mon, Feb 16 - Thu, Feb 19
Scandinavian Airlines Logo
7:20 pm - 11:55 amORD-BRU
33h 35m2 stops
Scandinavian Airlines Logo
8:30 pm - 4:45 pmBRU-ORD
27h 15m1 stop
$442Scandinavian Airlines
Find Deal
Fri, Nov 28 - Sun, Dec 7

Scandinavian Airlines flights from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport

Our best Scandinavian Airlines deals on Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport flight tickets
Scandinavian Airlines
Nov 5
ORD7:20 pmChicago O'Hare Intl
32h 30m
2 stops
BRU10:50 amBrussels Bruxelles-National
Dec 9
BRU11:30 amBrussels Bruxelles-National
36h 15m
2 stops
ORD4:45 pmChicago O'Hare Intl
$428
Find similar
Scandinavian Airlines
Nov 5
ORD7:20 pmChicago O'Hare Intl
32h 30m
2 stops
BRU10:50 amBrussels Bruxelles-National
Dec 9
BRU3:10 pmBrussels Bruxelles-National
32h 35m
1 stop
ORD4:45 pmChicago O'Hare Intl
$432
Find similar
Scandinavian Airlines
Nov 28
ORD7:20 pmChicago O'Hare Intl
33h 35m
2 stops
BRU11:55 amBrussels Bruxelles-National
Dec 7
BRU7:45 pmBrussels Bruxelles-National
28h 00m
2 stops
ORD4:45 pmChicago O'Hare Intl
$433
Find similar

Turkish Airlines flights from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport

Our best Turkish Airlines deals on Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport flight tickets
Turkish Airlines
Sep 6
ORD11:45 pmChicago O'Hare Intl
27h 05m
1 stop
BRU9:50 amBrussels Bruxelles-National
Sep 12
BRU4:15 pmBrussels Bruxelles-National
24h 25m
1 stop
ORD9:40 amChicago O'Hare Intl
$703
Find similar
Turkish Airlines
Sep 11
ORD7:50 pmChicago O'Hare Intl
18h 30m
1 stop
BRU9:20 pmBrussels Bruxelles-National
Sep 15
BRU2:25 pmBrussels Bruxelles-National
26h 15m
1 stop
ORD9:40 amChicago O'Hare Intl
$808
Find similar
Turkish Airlines
Sep 3
ORD11:45 pmChicago O'Hare Intl
27h 25m
1 stop
BRU10:10 amBrussels Bruxelles-National
Sep 10
BRU6:50 pmBrussels Bruxelles-National
21h 50m
1 stop
ORD9:40 amChicago O'Hare Intl
$817
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 28, 2025.
Use the filters below to find and compare flights from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

ChicagoBrussels

ORD - BRU

ORDBRU

Chicago O'Hare Intl

Wed 1/28

6:30 pm-11:55 am

1 stop10h 25m

Brussels Bruxelles-National

Fri 2/6

12:50 pm-5:20 pm

1 stop11h 30m

$423

ChicagoBrussels

ORD - BRU

ORDBRU

Chicago O'Hare Intl

Sun 10/5

7:25 pm-12:50 pm

1 stop10h 25m

Brussels Bruxelles-National

Thu 10/16

1:50 pm-6:15 pm

1 stop11h 25m

$425

ChicagoBrussels

ORD - BRU

ORDBRU

Chicago O'Hare Intl

Wed 11/5

7:20 pm-10:50 am

2 stops32h 30m

Brussels Bruxelles-National

Tue 12/9

11:30 am-4:45 pm

2 stops36h 15m

$428

ChicagoBrussels

ORD - BRU

ORDBRU

Chicago O'Hare Intl

Wed 11/5

7:20 pm-10:50 am

2 stops32h 30m

Brussels Bruxelles-National

Tue 12/9

3:10 pm-4:45 pm

1 stop32h 35m

$432

ChicagoBrussels

ORD - BRU

ORDBRU

Chicago O'Hare Intl

Fri 11/28

7:20 pm-11:55 am

2 stops33h 35m

Brussels Bruxelles-National

Sun 12/7

7:45 pm-4:45 pm

2 stops28h 00m

$433

ChicagoBrussels

ORD - BRU

ORDBRU

Chicago O'Hare Intl

Wed 11/5

7:20 pm-7:50 pm

1 stop17h 30m

Brussels Bruxelles-National

Tue 12/9

3:10 pm-4:45 pm

1 stop32h 35m

$435

ChicagoBrussels

ORD - BRU

ORDBRU

Chicago O'Hare Intl

Wed 1/28

7:20 pm-2:30 pm

1 stop12h 10m

Brussels Bruxelles-National

Mon 2/2

10:20 am-4:45 pm

1 stop13h 25m

$436

ChicagoBrussels

ORD - BRU

ORDBRU

Chicago O'Hare Intl

Wed 11/26

7:20 pm-7:50 pm

1 stop17h 30m

Brussels Bruxelles-National

Thu 12/4

10:20 am-4:45 pm

1 stop13h 25m

$439

ChicagoBrussels

ORD - BRU

ORDBRU

Chicago O'Hare Intl

Mon 2/16

7:20 pm-10:50 am

2 stops32h 30m

Brussels Bruxelles-National

Thu 2/19

7:20 pm-4:45 pm

2 stops28h 25m

$441

ChicagoBrussels

ORD - BRU

ORDBRU

Chicago O'Hare Intl

Fri 11/28

7:20 pm-11:55 am

2 stops33h 35m

Brussels Bruxelles-National

Sun 12/7

8:30 pm-4:45 pm

1 stop27h 15m

$442

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

See travel insights to Brussels from

How to get the cheapest flight ticket from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Brussels Bruxelles-National Airport?

The cheapest month to fly to Brussels Bruxelles-National Airport from Chicago O'Hare Intl Airport is in September. Flight prices, which tend to average around $547, are often lower during this time because this is during the off-season. If you aren’t able to travel during the month of September, then book flights to Brussels Bruxelles-National Airport from Chicago O'Hare Intl Airport during October instead. Flights to Brussels Bruxelles-National Airport in October, while not as cheap as those in September, still average around $582.

What is the cheapest day to depart on your flight to Brussels Bruxelles-National Airport?

The cheapest day to depart from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport is on a Wednesday. Travelers who choose to depart for Brussels Bruxelles-National Airport on a Wednesday will often find tickets for as low as $1,097. When flying out on a Saturday, the most expensive travel day of the week, you can expect to see flight prices from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport for around $1,308.

What is the cheapest time of day to depart on your flight to Brussels Bruxelles-National Airport?

Our most recent data shows that the best time of day to fly to Brussels Bruxelles-National Airport is in the evening. Flights from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport during this time can be as low as $579. If you have a flexible travel schedule, then try to avoid flying in the afternoon when prices are $1,179 on average. Flights to Brussels Bruxelles-National Airport from Chicago O'Hare Intl Airport in the afternoon are generally more expensive because this time of day is more convenient for travelers’ schedules.

What is the cheapest Chicago O'Hare Intl to Brussels Bruxelles-National flight route?

Fly from Chicago O'Hare Intl to Brussels Bruxelles-National for the best Chicago O'Hare Intl - Brussels Bruxelles-National flight prices

How far in advance should I book a flight to Brussels Bruxelles-National Airport?

You are more likely to see cheaper flights to Brussels Bruxelles-National Airport from Chicago O'Hare Intl Airport when booking weeks ahead of your departure date. In general, you can expect to find flights to Brussels Bruxelles-National Airport for around $779 when searching weeks out. However, flight prices might be lower outside of this timeframe. For example, people recently found flights to Brussels Bruxelles-National Airport from Chicago O'Hare Intl Airport for as low as $597 on momondo.

What cabin class options are available on Chicago O'Hare Intl to Brussels Bruxelles-National flights?

There are 3 cabin classes available to choose from on Chicago O'Hare Intl to Brussels Bruxelles-National flights. Cabin price and availability will vary by airline so perform a search above to find the right deals for you.

How have Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport flight prices changed over time?

As of August 2025, prices for Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport flights are approximately 54% cheaper when compared to flights at the same time last year.

When to book flights from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport

Are you open to changing your travel dates? Check out the ideal times to fly from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport (ORD to BRU) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport

Best Price Found

$612

Fastest flight time

8h 00m

Direct flights

Every day
The best one-way flight to Brussels Bruxelles-National Airport from Chicago O'Hare Intl Airport in the past 72 hours is $612. The best round-trip flight deal from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport found on momondo in the last 72 hours is $751.
The fastest flight from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport takes 8h 00m
Direct flights go from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport every day.
Search flight deals

  • How far is Chicago O'Hare Intl to Brussels Bruxelles-National by plane?

    Chicago O'Hare Intl and Brussels Bruxelles-National are 4144.8 mi apart from one another. Flights usually cover this in 10h 25m, depending on flying conditions and air traffic around both airports.

  • When did momondo last update prices for flights from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport?

    Prices for flights from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport are updated daily.

  • How many operators does momondo search for flights from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport?

  • How old do you have to be to fly from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport?

    The minimum age a child must be to fly alone is five but airlines that offer an unaccompanied minor (UNMR) service will have their own age restrictions, including rules around flight length, timings, and stopovers. We always recommend checking with the individual airline you are booking with to travel from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport.

  • What documentation or ID do you need to fly to Brussels Bruxelles-National Airport?

    The required travel and health documents for your Brussels Bruxelles-National Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Brussels Bruxelles-National Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

  • What is the most popular plane model from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport?

  • What is the most popular airline from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport?

Best airlines flying from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport

Compare and see reviews for airlines that fly from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport with momondo
Airline
Rating
Free Cancellation
Price
Scandinavian AirlinesPriceFrom $312Free CancellationRating
7.4
1,481 reviews
Search Scandinavian Airlines flights
IcelandairPriceFrom $405Free CancellationRating
7.0
534 reviews
Search Icelandair flights
Turkish AirlinesPriceFrom $492Free CancellationRating
7.3
3,954 reviews
Search Turkish Airlines flights
KLMPriceFrom $506Free CancellationRating
7.8
1,382 reviews
Search KLM flights
Aer LingusPriceFrom $536Free CancellationRating
7.2
1,239 reviews
Search Aer Lingus flights
TAP AIR PORTUGALPriceFrom $542Free CancellationRating
7.1
1,963 reviews
Search TAP AIR PORTUGAL flights
United AirlinesPriceFrom $590Free CancellationRating
7.4
8,944 reviews
Search United Airlines flights
LufthansaPriceFrom $728Free CancellationRating
6.8
7,368 reviews
Search Lufthansa flights

  • United Airlines Flights From Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport

    United Airlines flight deals from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport start from $590 round-trip. Over the 7 United Airlines flights for this route in a normal week, average airfare is usually $1,032 round-trip - but some users have found much cheaper deals with momondo.

  • Lufthansa Flights From Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport

    Another popular option for Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport flights is Lufthansa (6.8/10, 7,368 ratings). Lufthansa flies from Chicago O'Hare Intl Airport to Brussels Bruxelles-National Airport around 7 times per week, with deals starting from $728 round-trip and rising to an average price of around $1,110.

Traveling to a place near Brussels?

Book flights to Brussels if you plan to visit one of these locations
Ghent
Bruges
Leuven
Charleroi
Hasselt
Spa
Aalst
Namur
Mons
Zaventem
Dinant
Waterloo
Genk
Mechelen
Francorchamps
Knokke-Heist
Tournai
Durbuy
Oostkamp

Why use momondo?

Why should I use momondo to find a flight deal from Chicago to Brussels?

momondo compares prices from hundreds of airlines and agents so you can find and book the best deal on flights from Chicago to Brussels. Millions of users trust and use momondo every year so you are in good hands.

Can I find flights from Chicago to Brussels with flexible booking policies on momondo?

Yes. momondo allows you to filter the results for Chicago to Brussels flights to just show those with flexible booking policies.

How can momondo help me find flights from Chicago to Brussels?

momondo provides multiple filters to help you find the best flight to Brussels from Chicago. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Chicago to Brussels right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Brussels, momondo offers a useful price alert feature which will track prices for flights to Brussels from Chicago and alert you when they change.

An easier way to manage your Brussels Bruxelles-National Airport trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Tue 9/2
Tue 9/9
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Brussels

Popular cities in Belgium

Popular flights according to clicks in the last 7 days on momondo
Flights to Charleroi Brussels Airportfrom $449