Latest deals
Insights
FAQs
Reviews
Price Alerts

Cheap flights from Iowa to Santiago from $396

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Santiago departing on 11/7. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

Discover deals from 900+ travel sites with momondo.

Save money when you book flights with momondo

Big names and deals

Big names and deals

Search 100s of travel sites to compare prices.

Filter for what you want

Filter for what you want

Free Wi-Fi? Stopover? Instantly customize your results.

Trusted and free

Trusted and free

We’re completely free to use - no hidden charges or fees.

Price Alerts

Price Alerts

Not ready to book? to track prices.
Search flight deals

Find the cheapest flights from Iowa to Santiago

Cheap round-trip flights

Multiple Airlines Logo
5:49 pm - 4:17 amDSM-SCL
31h 28m3 stops
Multiple Airlines Logo
5:50 am - 5:08 pmSCL-DSM
38h 18m3 stops
$740Multiple Airlines
Find Deal
Thu, Nov 6 - Thu, Nov 13
Multiple Airlines Logo
5:49 pm - 4:17 amDSM-SCL
31h 28m3 stops
Multiple Airlines Logo
12:30 pm - 5:08 pmSCL-DSM
31h 38m3 stops
$742Multiple Airlines
Find Deal
Thu, Nov 6 - Thu, Nov 13
LATAM Airlines Logo
5:15 pm - 3:30 pmDSM-SCL
20h 15m2 stops
LATAM Airlines Logo
4:55 pm - 10:23 amSCL-DSM
18h 28m2 stops
$804LATAM Airlines
Find Deal
Mon, Mar 9 - Thu, Apr 9
LATAM Airlines Logo
11:04 am - 2:10 pmDSM-SCL
25h 06m3 stops
LATAM Airlines Logo
4:55 pm - 10:23 amSCL-DSM
18h 28m2 stops
$808LATAM Airlines
Find Deal
Mon, Mar 9 - Thu, Apr 9
Delta Logo
5:35 am - 6:35 amDSM-SCL
22h 00m2 stops
Delta Logo
6:30 pm - 10:42 amSCL-DSM
19h 12m2 stops
$870Delta
Find Deal
Mon, Nov 17 - Mon, Nov 24
Delta Logo
11:01 am - 7:40 amDSM-SCL
17h 39m2 stops
Delta Logo
4:35 am - 10:33 pmSCL-DSM
20h 58m2 stops
$914Delta
Find Deal
Mon, Dec 8 - Thu, Dec 11
United Airlines Logo
2:52 pm - 8:50 amOMA-SCL
14h 58m1 stop
United Airlines Logo
10:45 pm - 8:09 pmSCL-OMA
24h 24m2 stops
$953United Airlines
Find Deal
Thu, Nov 6 - Thu, Nov 13
American Airlines Logo
3:38 pm - 7:55 amOMA-SCL
13h 17m1 stop
American Airlines Logo
10:25 pm - 11:56 pmSCL-OMA
28h 31m1 stop
$961American Airlines
Find Deal
Thu, Nov 6 - Thu, Nov 13
American Airlines Logo
6:00 am - 9:00 amDSM-SCL
24h 00m1 stop
American Airlines Logo
10:25 pm - 11:38 pmSCL-DSM
28h 13m1 stop
$983American Airlines
Find Deal
Thu, Nov 6 - Thu, Nov 13
United Airlines Logo
6:05 am - 8:50 amDSM-SCL
23h 45m1 stop
United Airlines Logo
10:45 pm - 2:11 pmSCL-DSM
18h 26m1 stop
$987United Airlines
Find Deal
Thu, Nov 6 - Thu, Nov 13

LATAM Airlines flights from Iowa to Santiago

Our best LATAM Airlines deals on Iowa to Santiago flight tickets
LATAM Airlines
Mar 9
DSM5:15 pmDes Moines
20h 15m
2 stops
SCL3:30 pmSantiago Arturo Merino Benitez
Apr 9
SCL4:55 pmSantiago Arturo Merino Benitez
18h 28m
2 stops
DSM10:23 amDes Moines
$804
Find similar
LATAM Airlines
Mar 9
DSM11:04 amDes Moines
25h 06m
3 stops
SCL2:10 pmSantiago Arturo Merino Benitez
Apr 9
SCL4:55 pmSantiago Arturo Merino Benitez
18h 28m
2 stops
DSM10:23 amDes Moines
$808
Find similar
LATAM Airlines
Dec 8
DSM2:15 pmDes Moines
14h 25m
1 stop
SCL7:40 amSantiago Arturo Merino Benitez
Dec 11
SCL4:35 amSantiago Arturo Merino Benitez
20h 58m
2 stops
DSM10:33 pmDes Moines
$910
Find similar

Delta flights from Iowa to Santiago

Our best Delta deals on Iowa to Santiago flight tickets
Delta
Nov 17
DSM5:35 amDes Moines
22h 00m
2 stops
SCL6:35 amSantiago Arturo Merino Benitez
Nov 24
SCL6:30 pmSantiago Arturo Merino Benitez
19h 12m
2 stops
DSM10:42 amDes Moines
$870
Find similar
Delta
Dec 8
DSM11:01 amDes Moines
17h 39m
2 stops
SCL7:40 amSantiago Arturo Merino Benitez
Dec 11
SCL4:35 amSantiago Arturo Merino Benitez
20h 58m
2 stops
DSM10:33 pmDes Moines
$914
Find similar
Delta
Nov 6
DSM2:13 pmDes Moines
21h 22m
2 stops
SCL2:35 pmSantiago Arturo Merino Benitez
Nov 12
SCL12:55 amSantiago Arturo Merino Benitez
19h 51m
2 stops
DSM5:46 pmDes Moines
$1,104
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated September 23, 2025.
Use the filters below to find and compare flights from Iowa to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 11/6

5:49 pm-4:17 am

3 stops31h 28m

Santiago Arturo Merino Benitez

Thu 11/13

5:50 am-5:08 pm

3 stops38h 18m

$740

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 11/6

5:49 pm-4:17 am

3 stops31h 28m

Santiago Arturo Merino Benitez

Thu 11/13

12:30 pm-5:08 pm

3 stops31h 38m

$742

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Mon 3/9

5:15 pm-3:30 pm

2 stops20h 15m

Santiago Arturo Merino Benitez

Thu 4/9

4:55 pm-10:23 am

2 stops18h 28m

$804

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Mon 3/9

11:04 am-2:10 pm

3 stops25h 06m

Santiago Arturo Merino Benitez

Thu 4/9

4:55 pm-10:23 am

2 stops18h 28m

$808

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Mon 11/17

5:35 am-6:35 am

2 stops22h 00m

Santiago Arturo Merino Benitez

Mon 11/24

6:30 pm-10:42 am

2 stops19h 12m

$870

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Mon 12/8

11:01 am-7:40 am

2 stops17h 39m

Santiago Arturo Merino Benitez

Thu 12/11

4:35 am-10:33 pm

2 stops20h 58m

$914

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Thu 11/6

2:52 pm-8:50 am

1 stop14h 58m

Santiago Arturo Merino Benitez

Thu 11/13

10:45 pm-8:09 pm

2 stops24h 24m

$953

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

Thu 11/6

3:38 pm-7:55 am

1 stop13h 17m

Santiago Arturo Merino Benitez

Thu 11/13

10:25 pm-11:56 pm

1 stop28h 31m

$961

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 11/6

6:00 am-9:00 am

1 stop24h 00m

Santiago Arturo Merino Benitez

Thu 11/13

10:25 pm-11:38 pm

1 stop28h 13m

$983

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

Thu 11/6

6:05 am-8:50 am

1 stop23h 45m

Santiago Arturo Merino Benitez

Thu 11/13

10:45 pm-2:11 pm

1 stop18h 26m

$987

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

See travel insights to Santiago from

How to get the cheapest flight ticket from Iowa to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $958. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Thursday is $1,692.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Iowa to Santiago when you can find flight prices for as low as $768. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,081 per ticket.

Can stopping save me money on Iowa to Santiago flights?

You could potentially save up to 23% on your flight if you consider stops on a Iowa to Santiago flight.

Cheap Iowa to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Santiago

Direct flights

None
There are no direct flights from Iowa to Santiago. There are no popular flight routes from Iowa to Santiago.
Search flight deals

  • When did momondo last update prices for flights from Iowa to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Iowa to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Iowa to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Iowa to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Iowa to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Iowa to Santiago

Compare and see reviews for airlines that fly from Iowa to Santiago with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $808Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
LATAM AirlinesPriceFrom $843Free CancellationRating
7.5
1,854 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Santiago?

It is quick and easy to find Iowa to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Iowa to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Iowa which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Iowa to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Iowa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Iowa to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Iowa to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

An easier way to manage your Santiago trip

We make it super easy to schedule, organize and travel with friends or family. Trips is free — and available to use no matter where you book.
Start using Trips
Find my bookings

Get notified when prices go down

Daily price changes in your inbox - only with Price Alerts.
1 adult
Thu 10/23
Thu 10/30
By creating a price alert you accept our terms of use and privacy policy.

Find better results for your trip to Chile