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Cheap flights from Iowa to Santiago from $381

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Iowa to Santiago departing on 12/15. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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0 bags

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Find the cheapest flights from Iowa to Santiago

Cheap round-trip flights

LATAM Airlines Logo
11:25 am - 6:45 amDSM-SCL
17h 20m2 stops
LATAM Airlines Logo
12:25 am - 5:45 pmSCL-DSM
19h 20m2 stops
$783LATAM Airlines
Find Deal
jue., sep. 18 - mié., sep. 24
Delta Logo
11:17 am - 5:45 amDSM-SCL
16h 28m2 stops
Delta Logo
5:55 pm - 1:28 pmSCL-DSM
21h 33m2 stops
$784Delta
Find Deal
mié., oct. 1 - mié., oct. 8
American Airlines Logo
12:04 pm - 7:55 amOMA-SCL
17h 51m2 stops
American Airlines Logo
10:15 pm - 11:40 pmSCL-OMA
28h 25m1 stop
$788American Airlines
Find Deal
mar., sep. 16 - lun., nov. 3
American Airlines Logo
1:42 pm - 7:55 amOMA-SCL
16h 13m2 stops
American Airlines Logo
11:15 pm - 11:30 pmSCL-OMA
27h 15m1 stop
$789American Airlines
Find Deal
mar., sep. 16 - lun., nov. 3
United Airlines Logo
6:45 pm - 8:50 amDSM-SCL
35h 05m2 stops
United Airlines Logo
10:45 pm - 9:36 pmSCL-DSM
25h 51m2 stops
$808United Airlines
Find Deal
dom., feb. 1 - lun., feb. 16
United Airlines Logo
11:31 am - 8:50 amCID-SCL
18h 19m2 stops
United Airlines Logo
10:45 pm - 9:20 pmSCL-CID
25h 35m2 stops
$828United Airlines
Find Deal
lun., dic. 8 - vie., dic. 12
Logo
4:38 pm - 4:17 amDSM-SCL
33h 39m3 stops
Logo
12:25 am - 1:32 pmSCL-DSM
39h 07m3 stops
$971
Find Deal
jue., sep. 18 - mié., sep. 24
Logo
4:38 pm - 4:17 amDSM-SCL
33h 39m3 stops
Logo
5:22 am - 2:58 pmSCL-DSM
35h 36m3 stops
$1,135
Find Deal
jue., sep. 18 - jue., sep. 25
Copa Airlines Logo
10:50 am - 6:01 amMLI-SCL
16h 11m2 stops
Copa Airlines Logo
1:28 am - 5:05 pmSCL-MLI
18h 37m2 stops
$2,449Copa Airlines
Find Deal
lun., dic. 8 - jue., dic. 11
Copa Airlines Logo
10:50 am - 6:01 amMLI-SCL
16h 11m2 stops
Copa Airlines Logo
1:29 am - 5:05 pmSCL-MLI
18h 36m2 stops
$2,851Copa Airlines
Find Deal
lun., dic. 8 - jue., dic. 11

United Airlines flights from Iowa to Santiago

Our best United Airlines deals on Iowa to Santiago flight tickets
United Airlines
Feb 1
DSM6:45 pmDes Moines
35h 05m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Feb 16
SCL10:45 pmSantiago Arturo Merino Benitez
25h 51m
2 stops
DSM9:36 pmDes Moines
$808
Find similar
United Airlines
Dec 8
CID11:31 amCedar Rapids
18h 19m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Dec 12
SCL10:45 pmSantiago Arturo Merino Benitez
25h 35m
2 stops
CID9:20 pmCedar Rapids
$828
Find similar
United Airlines
Dec 4
MLI6:30 amMoline Quad-City
23h 20m
2 stops
SCL8:50 amSantiago Arturo Merino Benitez
Dec 8
SCL10:45 pmSantiago Arturo Merino Benitez
16h 05m
2 stops
MLI11:50 amMoline Quad-City
$838
Find similar

LATAM Airlines flights from Iowa to Santiago

Our best LATAM Airlines deals on Iowa to Santiago flight tickets
LATAM Airlines
Sep 18
DSM11:25 amDes Moines
17h 20m
2 stops
SCL6:45 amSantiago Arturo Merino Benitez
Sep 24
SCL12:25 amSantiago Arturo Merino Benitez
19h 20m
2 stops
DSM5:45 pmDes Moines
$783
Find similar
LATAM Airlines
Dec 8
DSM5:45 amDes Moines
19h 45m
2 stops
SCL4:30 amSantiago Arturo Merino Benitez
Dec 11
SCL4:35 amSantiago Arturo Merino Benitez
20h 48m
2 stops
DSM10:23 pmDes Moines
$824
Find similar
LATAM Airlines
Feb 1
DSM5:15 pmDes Moines
34h 45m
1 stop
SCL7:00 amSantiago Arturo Merino Benitez
Feb 18
SCL11:15 pmSantiago Arturo Merino Benitez
14h 08m
1 stop
DSM10:23 amDes Moines
$839
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Iowa to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated agosto 7, 2025.
Use the filters below to find and compare flights from Iowa to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

jue. 9/18

11:25 am-6:45 am

2 stops17h 20m

Santiago Arturo Merino Benitez

mié. 9/24

12:25 am-5:45 pm

2 stops19h 20m

$783

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

mié. 10/1

11:17 am-5:45 am

2 stops16h 28m

Santiago Arturo Merino Benitez

mié. 10/8

5:55 pm-1:28 pm

2 stops21h 33m

$784

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

mar. 9/16

12:04 pm-7:55 am

2 stops17h 51m

Santiago Arturo Merino Benitez

lun. 11/3

10:15 pm-11:40 pm

1 stop28h 25m

$788

OmahaSantiago

OMA - SCL

OMASCL

Omaha Eppley Airfield

mar. 9/16

1:42 pm-7:55 am

2 stops16h 13m

Santiago Arturo Merino Benitez

lun. 11/3

11:15 pm-11:30 pm

1 stop27h 15m

$789

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

dom. 2/1

6:45 pm-8:50 am

2 stops35h 05m

Santiago Arturo Merino Benitez

lun. 2/16

10:45 pm-9:36 pm

2 stops25h 51m

$808

Cedar RapidsSantiago

CID - SCL

CIDSCL

Cedar Rapids

lun. 12/8

11:31 am-8:50 am

2 stops18h 19m

Santiago Arturo Merino Benitez

vie. 12/12

10:45 pm-9:20 pm

2 stops25h 35m

$828

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

jue. 9/18

4:38 pm-4:17 am

3 stops33h 39m

Santiago Arturo Merino Benitez

mié. 9/24

12:25 am-1:32 pm

3 stops39h 07m

$971

Des MoinesSantiago

DSM - SCL

DSMSCL

Des Moines

jue. 9/18

4:38 pm-4:17 am

3 stops33h 39m

Santiago Arturo Merino Benitez

jue. 9/25

5:22 am-2:58 pm

3 stops35h 36m

$1,135

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

lun. 12/8

10:50 am-6:01 am

2 stops16h 11m

Santiago Arturo Merino Benitez

jue. 12/11

1:28 am-5:05 pm

2 stops18h 37m

$2,449

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

lun. 12/8

10:50 am-6:01 am

2 stops16h 11m

Santiago Arturo Merino Benitez

jue. 12/11

1:29 am-5:05 pm

2 stops18h 36m

$2,851

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Iowa to Santiago

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest day to depart on your flight to Santiago?

The cheapest day to depart on your flight to Santiago is on a Tuesday when prices can be found for as low as $958. This is often the case because there is less demand to fly during this day of the week. Be sure to avoid booking your departure on a Thursday as prices are generally higher than usual. According to our data, the average ticket price to Santiago on Thursday is $1,692.

What is the cheapest time of day to depart on your flight to Santiago?

In the afternoon is the cheapest time of day to fly from Iowa to Santiago when you can find flight prices for as low as $768. Flying to Santiago in the afternoon is an ideal time because this is during off-peak travel hours. In the morning is when there is more demand to fly to Santiago, so prices are often more expensive at around $1,081 per ticket.

Can stopping save me money on Iowa to Santiago flights?

You could potentially save up to 23% on your flight if you consider stops on a Iowa to Santiago flight.

Cheap Iowa to Santiago flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Iowa to Santiago

Best Price Found

$381

Fastest flight time

12h 46m

Direct flights

None

Airports in Santiago

1 airport
The best one-way flight to Santiago from Iowa in the past 72 hours is $381. The best round-trip flight deal from Iowa to Santiago found on momondo in the last 72 hours is $783.
The fastest flight from Iowa to Santiago takes 12h 46m
There are no direct flights from Iowa to Santiago. Popular non-direct routes for this connection are Des Moines Airport - Santiago Arturo Merino Benitez Airport, Omaha Eppley Airfield Airport - Santiago Arturo Merino Benitez Airport and Cedar Rapids Airport - Santiago Arturo Merino Benitez Airport.
There is 1 airport near Santiago: Santiago Arturo Merino Benitez (SCL)
Search flight deals

  • When did momondo last update prices for flights from Iowa to Santiago Arturo Merino Benitez Airport?

    Prices for flights from Iowa to Santiago Arturo Merino Benitez Airport were last updated today.

  • How many operators does momondo search for flights from Iowa to Santiago Arturo Merino Benitez Airport?

  • How old do you have to be to fly from Iowa to Santiago Arturo Merino Benitez Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Iowa to Santiago Arturo Merino Benitez Airport.

  • What documentation or ID do you need to fly to Santiago Arturo Merino Benitez Airport?

    The required travel and health documents for your Santiago Arturo Merino Benitez Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santiago Arturo Merino Benitez Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Iowa to Santiago

Compare and see reviews for airlines that fly from Iowa to Santiago with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $742Free CancellationRating
7.2
10,000 reviews
Search American Airlines flights
DeltaPriceFrom $782Free CancellationRating
8.0
7,985 reviews
Search Delta flights
LATAM AirlinesPriceFrom $843Free CancellationRating
7.5
1,833 reviews
Search LATAM Airlines flights

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar
Santa Cruz
Valparaíso
Valle Nevado
San Fernando
Pichilemu

Why use momondo?

Why should I use momondo to find a flight deal from Iowa to Santiago?

It is quick and easy to find Iowa to Santiago flights on momondo. We search and return numerous flight options from various airlines and agents. You can then use our filters to narrow your search until you have found the most convenient flight to Santiago that suits you.

Can I find flights from Iowa to Santiago with flexible booking policies on momondo?

momondo does allow users to show only those flights to Santiago from Iowa which offer a flexible booking policy as well as other useful filters and features.

How can momondo help me find flights from Iowa to Santiago?

momondo provides multiple filters to help you find the best flight to Santiago from Iowa. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Iowa to Santiago right now. Can momondo alert me if prices change?

Of course. momondo tracks the price of Iowa to Santiago flights. All you need is a valid email address and we will do the rest; it is that quick and easy.

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