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Cheap flights from Illinois to Santa Cruz de la Sierra from $293

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Illinois to Santa Cruz de la Sierra departing on 11/28. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
1 adult, Economy, 0 bags

Discover deals from 900+ travel sites with momondo.

Find the cheapest flights from Illinois to Santa Cruz de la Sierra

Cheap round-trip flights

Enter your travel dates to find the best prices.
Copa Airlines Logo
7:35 am - 3:37 amORD  Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
18h 02m1 stop Panama City Tocumen Intl
Copa Airlines Logo
11:49 am - 12:11 amVVI  Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl
14h 22m1 stop Panama City Tocumen Intl
$568Copa Airlines
Sun, Nov 1 - Tue, Nov 17
Copa Airlines Logo
3:20 pm - 3:38 amORD  Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
11h 18m1 stop Panama City Tocumen Intl
Copa Airlines Logo
11:47 am - 1:02 amVVI  Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl
14h 15m1 stop Panama City Tocumen Intl
$568Copa Airlines
Mon, Sep 14 - Thu, Sep 17
Copa Airlines Logo
2:13 pm - 3:37 amORD  Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
11h 24m1 stop Panama City Tocumen Intl
Copa Airlines Logo
1:10 am - 12:11 amVVI  Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl
25h 01m1 stop Panama City Tocumen Intl
$568Copa Airlines
Wed, Nov 18 - Tue, Dec 8
Copa Airlines Logo
2:13 pm - 3:37 amORD  Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
11h 24m1 stop Panama City Tocumen Intl
Copa Airlines Logo
11:42 am - 12:46 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl
27h 04m1 stop Panama City Tocumen Intl
$568Copa Airlines
Wed, Nov 18 - Wed, Dec 9
United Airlines Logo
5:00 am - 10:44 pmORD  Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
40h 44m2 stops Newark Panama City Tocumen Intl
United Airlines Logo
11:47 am - 12:28 amVVI  Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl
37h 41m2 stops Panama City Tocumen Intl Newark
$603United Airlines
Mon, Sep 14 - Thu, Sep 17
United Airlines Logo
9:10 am - 3:37 amORD  Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
16h 27m2 stops Atlanta Hartsfield-Jackson Panama City Tocumen Intl
United Airlines Logo
11:49 am - 9:45 amVVI  Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl
23h 56m2 stops Panama City Tocumen Intl Washington, D.C. Dulles Intl
$603United Airlines
Sun, Nov 1 - Tue, Nov 17
United Airlines Logo
11:00 am - 3:37 amORD  Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
14h 37m2 stops Baltimore/Washington Panama City Tocumen Intl
United Airlines Logo
11:42 am - 12:15 amVVI  Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl
14h 33m2 stops Panama City Tocumen Intl Houston George Bush Intcntl
$603United Airlines
Wed, Nov 18 - Wed, Dec 9
Avianca Logo
11:20 pm - 2:30 amORD  Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
26h 10m1 stop Bogotá El Dorado
Avianca Logo
3:35 am - 9:20 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl
18h 45m1 stop Bogotá El Dorado
$716Avianca
Sat, Sep 12 - Mon, Sep 14
Avianca Logo
7:00 am - 2:35 amORD  Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
17h 35m2 stops Miami Bogotá El Dorado
Avianca Logo
3:40 am - 8:20 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl
18h 40m1 stop Bogotá El Dorado
$740Avianca
Wed, Nov 18 - Tue, Dec 8
Avianca Logo
6:59 am - 2:35 amORD  Chicago O'Hare Intl-VVI Santa Cruz de la Sierra Viru Viru Intl
17h 36m2 stops Miami Bogotá El Dorado
Avianca Logo
3:40 am - 8:20 pmVVI  Santa Cruz de la Sierra Viru Viru Intl-ORD Chicago O'Hare Intl
18h 40m1 stop Bogotá El Dorado
$740Avianca
Sun, Nov 1 - Mon, Nov 16

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Avianca flights from Illinois to Santa Cruz de la Sierra

Our best Avianca deals on Illinois to Santa Cruz de la Sierra flight tickets
Avianca
Sep 12
ORD11:20 pmChicago O'Hare Intl
26h 10m
1 stop
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
Sep 14
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
18h 45m
1 stop
ORD9:20 pmChicago O'Hare Intl
$716
Avianca
Nov 1
ORD6:59 amChicago O'Hare Intl
17h 36m
2 stops
VVI2:35 amSanta Cruz de la Sierra Viru Viru Intl
Nov 16
VVI3:40 amSanta Cruz de la Sierra Viru Viru Intl
18h 40m
1 stop
ORD8:20 pmChicago O'Hare Intl
$740
Avianca
Sep 14
ORD7:30 amChicago O'Hare Intl
18h 00m
2 stops
VVI2:30 amSanta Cruz de la Sierra Viru Viru Intl
Sep 16
VVI3:35 amSanta Cruz de la Sierra Viru Viru Intl
18h 45m
1 stop
ORD9:20 pmChicago O'Hare Intl
$748

Copa Airlines flights from Illinois to Santa Cruz de la Sierra

Our best Copa Airlines deals on Illinois to Santa Cruz de la Sierra flight tickets
Copa Airlines
Sep 14
ORD3:20 pmChicago O'Hare Intl
11h 18m
1 stop
VVI3:38 amSanta Cruz de la Sierra Viru Viru Intl
Sep 17
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
14h 15m
1 stop
ORD1:02 amChicago O'Hare Intl
$568
Copa Airlines
Sep 30
ORD3:20 pmChicago O'Hare Intl
30h 24m
1 stop
VVI10:44 pmSanta Cruz de la Sierra Viru Viru Intl
Oct 24
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
26h 59m
1 stop
ORD1:46 pmChicago O'Hare Intl
$589
Copa Airlines
Sep 30
ORD3:20 pmChicago O'Hare Intl
30h 24m
1 stop
VVI10:44 pmSanta Cruz de la Sierra Viru Viru Intl
Oct 24
VVI11:47 amSanta Cruz de la Sierra Viru Viru Intl
26h 59m
1 stop
ORD1:46 pmChicago O'Hare Intl
$601

momondo Fare Finder

 
Customize your flight search to find flights from Illinois to Santa Cruz de la Sierra that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from Illinois to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Sun 11/1

7:35 am-3:37 am

1 stop18h 02m

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/17

11:49 am-12:11 am

1 stop14h 22m

$568
Quickest round-trip

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Mon 9/14

3:20 pm-3:38 am

1 stop11h 18m

Santa Cruz de la Sierra Viru Viru Intl

Thu 9/17

11:47 am-1:02 am

1 stop14h 15m

$568

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Wed 11/18

2:13 pm-3:37 am

1 stop11h 24m

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/8

1:10 am-12:11 am

1 stop25h 01m

$568

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Wed 11/18

2:13 pm-3:37 am

1 stop11h 24m

Santa Cruz de la Sierra Viru Viru Intl

Wed 12/9

11:42 am-12:46 pm

1 stop27h 04m

$568

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Mon 9/14

5:00 am-10:44 pm

2 stops40h 44m

Santa Cruz de la Sierra Viru Viru Intl

Thu 9/17

11:47 am-12:28 am

2 stops37h 41m

$603

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Sun 11/1

9:10 am-3:37 am

2 stops16h 27m

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/17

11:49 am-9:45 am

2 stops23h 56m

$603

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Wed 11/18

11:00 am-3:37 am

2 stops14h 37m

Santa Cruz de la Sierra Viru Viru Intl

Wed 12/9

11:42 am-12:15 am

2 stops14h 33m

$603

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Sat 9/12

11:20 pm-2:30 am

1 stop26h 10m

Santa Cruz de la Sierra Viru Viru Intl

Mon 9/14

3:35 am-9:20 pm

1 stop18h 45m

$716

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Wed 11/18

7:00 am-2:35 am

2 stops17h 35m

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/8

3:40 am-8:20 pm

1 stop18h 40m

$740

ChicagoSanta Cruz de la Sierra

ORD Chicago O'Hare Intl - VVI Santa Cruz de la Sierra Viru Viru Intl

ORDVVI

Chicago O'Hare Intl

Sun 11/1

6:59 am-2:35 am

2 stops17h 36m

Santa Cruz de la Sierra Viru Viru Intl

Mon 11/16

3:40 am-8:20 pm

1 stop18h 40m

$740

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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How to get the cheapest flight ticket from Illinois to Santa Cruz de la Sierra

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the cheapest month to fly to Santa Cruz de la Sierra?

The cheapest month to fly to Santa Cruz de la Sierra from Illinois is in November. Flight prices, which tend to average around $555, are often lower during this time because this is during the off-season. If you don’t want to visit Santa Cruz de la Sierra in November, then you should wait until October to fly from Illinois, when ticket prices are also cheap, with an average price of $569.

Can stopping save me money on Illinois to Santa Cruz de la Sierra flights?

You could potentially save up to 25% on your flight if you consider stops on a Illinois to Santa Cruz de la Sierra flight.

Cheap Illinois to Santa Cruz de la Sierra flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Illinois to Santa Cruz de la Sierra

Fastest flight time

11h 18m

Direct flights

None
The fastest flight from Illinois to Santa Cruz de la Sierra takes 11h 18m
There are no direct flights from Illinois to Santa Cruz de la Sierra. There are no popular flight routes from Illinois to Santa Cruz de la Sierra.
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Frequently asked questions about flying from Illinois to Santa Cruz de la Sierra

  • When did momondo last update prices for flights from Illinois to Santa Cruz de la Sierra Viru Viru Intl Airport?

    Prices for flights from Illinois to Santa Cruz de la Sierra Viru Viru Intl Airport refresh daily.

  • How many operators does momondo search for flights from Illinois to Santa Cruz de la Sierra Viru Viru Intl Airport?

  • How old do you have to be to fly from Illinois to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The minimum age for a child to fly alone is five, but airlines offering an unaccompanied minor (UNMR) service may have their age restrictions, such as regulations concerning flight duration, timing, and layovers. It is recommended that you verify with the airline you are booking with for travel from Illinois to Santa Cruz de la Sierra Viru Viru Intl Airport.

  • What documentation or ID do you need to fly to Santa Cruz de la Sierra Viru Viru Intl Airport?

    The required travel and health documents for your Santa Cruz de la Sierra Viru Viru Intl Airport trip may vary depending on your itinerary and personal circumstances. As a general rule, you should carry multiple documents, including a national ID card or driver's license and a passport valid for six months after your intended arrival at Santa Cruz de la Sierra Viru Viru Intl Airport. We recommend that you seek guidance from your airline or a reliable third party such as IATA.

Best airlines flying from Illinois to Santa Cruz de la Sierra

Compare and see reviews for airlines that fly from Illinois to Santa Cruz de la Sierra with momondo
Airline
Rating
Free Cancellation
Price
Copa AirlinesPriceFrom $458Free CancellationRating
7.6
1,559 reviews
Search Copa Airlines flights
United AirlinesPriceFrom $506Free CancellationRating
7.4
10,113 reviews
Search United Airlines flights

Why use momondo?

Why should I use momondo to find a flight deal from Illinois to Santa Cruz de la Sierra?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santa Cruz de la Sierra from Illinois.

Can I find flights from Illinois to Santa Cruz de la Sierra with flexible booking policies on momondo?

Flights from Illinois to Santa Cruz de la Sierra with flexible booking policies can be found by using the search form above and then selecting our dedicated flexible booking filter, which will highlight only the flights where this policy is applied.

How can momondo help me find flights from Illinois to Santa Cruz de la Sierra?

Once all potential Illinois to Santa Cruz de la Sierra flight options are in front of you, momondo lets you sort and filter flights based on preferences such as airline, price and flight times amongst many other options.

I’m not ready to book a flight from Illinois to Santa Cruz de la Sierra right now. Can momondo alert me if prices change?

If you are simply researching potential flights to Santa Cruz de la Sierra, momondo offers a useful price alert feature which will track prices for flights to Santa Cruz de la Sierra from Illinois and alert you when they change.

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