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Cheap flights from Harrisburg to Santo Domingo from $346

This is the cheapest round-trip flight price found by a momondo user in the last 72 hours by searching for a flight from Harrisburg to Santo Domingo departing on 1/12. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
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Find the cheapest flights from Harrisburg to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:00 am - 9:50 pmMDT-SDQ
13h 50m2 stops
American Airlines Logo
1:23 pm - 11:37 pmSDQ-MDT
11h 14m2 stops
$346American Airlines
Find Deal
Mon, Jan 12 - Tue, Jan 27
Frontier Logo
6:03 pm - 9:41 amMDT-SDQ
14h 38m1 stop
Frontier Logo
10:56 am - 5:41 pmSDQ-MDT
7h 45m1 stop
$366Frontier
Find Deal
Sat, Jan 10 - Sat, Jan 17
American Airlines Logo
6:28 am - 11:35 amMDT-SDQ
28h 07m2 stops
American Airlines Logo
6:20 pm - 10:20 pmSDQ-MDT
29h 00m2 stops
$406American Airlines
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Tue, Mar 3 - Thu, Mar 5
American Airlines Logo
7:39 am - 11:00 pmMDT-SDQ
14h 21m2 stops
American Airlines Logo
6:20 pm - 10:20 pmSDQ-MDT
29h 00m2 stops
$422American Airlines
Find Deal
Tue, Mar 3 - Thu, Mar 5
American Airlines Logo
10:42 am - 9:50 pmMDT-SDQ
10h 08m1 stop
American Airlines Logo
1:23 pm - 11:27 pmSDQ-MDT
11h 04m1 stop
$440American Airlines
Find Deal
Sat, Jan 10 - Sat, Jan 17
United Airlines Logo
6:30 am - 11:46 pmMDT-SDQ
16h 16m2 stops
United Airlines Logo
6:00 am - 9:20 pmSDQ-MDT
16h 20m2 stops
$456United Airlines
Find Deal
Tue, Mar 3 - Thu, Mar 5
Delta Logo
6:00 am - 2:15 pmMDT-SDQ
7h 15m1 stop
Delta Logo
3:40 pm - 11:40 pmSDQ-MDT
9h 00m1 stop
$520Delta
Find Deal
Tue, Mar 3 - Thu, Mar 5
United Airlines Logo
6:30 am - 11:46 pmMDT-SDQ
16h 16m2 stops
United Airlines Logo
6:00 am - 9:15 pmSDQ-MDT
16h 15m2 stops
$526United Airlines
Find Deal
Sat, Jan 10 - Sat, Jan 17
Delta Logo
6:00 am - 2:15 pmMDT-SDQ
7h 15m1 stop
Delta Logo
3:40 pm - 11:40 pmSDQ-MDT
9h 00m1 stop
$538Delta
Find Deal
Tue, Mar 3 - Thu, Mar 5
Delta Logo
6:00 am - 1:41 pmMDT-SDQ
7h 41m1 stop
Delta Logo
3:56 pm - 11:08 pmSDQ-MDT
8h 12m1 stop
$545Delta
Find Deal
Sat, Nov 1 - Thu, Nov 6

Delta flights from Harrisburg to Santo Domingo

Our best Delta deals on Harrisburg to Santo Domingo flight tickets
Delta
Mar 3
MDT6:00 amHarrisburg
7h 15m
1 stop
SDQ2:15 pmSanto Domingo Las Americas
Mar 5
SDQ3:40 pmSanto Domingo Las Americas
9h 00m
1 stop
MDT11:40 pmHarrisburg
$520
Find similar
Delta
Mar 3
MDT6:00 amHarrisburg
7h 15m
1 stop
SDQ2:15 pmSanto Domingo Las Americas
Mar 5
SDQ3:40 pmSanto Domingo Las Americas
9h 00m
1 stop
MDT11:40 pmHarrisburg
$538
Find similar
Delta
Nov 1
MDT6:00 amHarrisburg
7h 41m
1 stop
SDQ1:41 pmSanto Domingo Las Americas
Nov 6
SDQ3:56 pmSanto Domingo Las Americas
8h 12m
1 stop
MDT11:08 pmHarrisburg
$545
Find similar

American Airlines flights from Harrisburg to Santo Domingo

Our best American Airlines deals on Harrisburg to Santo Domingo flight tickets
American Airlines
Jan 12
MDT7:00 amHarrisburg
13h 50m
2 stops
SDQ9:50 pmSanto Domingo Las Americas
Jan 27
SDQ1:23 pmSanto Domingo Las Americas
11h 14m
2 stops
MDT11:37 pmHarrisburg
$346
Find similar
American Airlines
Oct 15
MDT9:33 amHarrisburg
10h 57m
2 stops
SDQ8:30 pmSanto Domingo Las Americas
Nov 4
SDQ1:19 pmSanto Domingo Las Americas
11h 34m
2 stops
MDT11:53 pmHarrisburg
$393
Find similar
American Airlines
Mar 3
MDT6:28 amHarrisburg
28h 07m
2 stops
SDQ11:35 amSanto Domingo Las Americas
Mar 5
SDQ6:20 pmSanto Domingo Las Americas
29h 00m
2 stops
MDT10:20 pmHarrisburg
$406
Find similar

momondo Fare Finder

 
Customize your flight search to find flights from Harrisburg to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated October 9, 2025.
Use the filters below to find and compare flights from Harrisburg to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Mon 1/12

7:00 am-9:50 pm

2 stops13h 50m

Santo Domingo Las Americas

Tue 1/27

1:23 pm-11:37 pm

2 stops11h 14m

$346

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sat 1/10

6:03 pm-9:41 am

1 stop14h 38m

Santo Domingo Las Americas

Sat 1/17

10:56 am-5:41 pm

1 stop7h 45m

$366

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Tue 3/3

6:28 am-11:35 am

2 stops28h 07m

Santo Domingo Las Americas

Thu 3/5

6:20 pm-10:20 pm

2 stops29h 00m

$406

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Tue 3/3

7:39 am-11:00 pm

2 stops14h 21m

Santo Domingo Las Americas

Thu 3/5

6:20 pm-10:20 pm

2 stops29h 00m

$422

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sat 1/10

10:42 am-9:50 pm

1 stop10h 08m

Santo Domingo Las Americas

Sat 1/17

1:23 pm-11:27 pm

1 stop11h 04m

$440

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Tue 3/3

6:30 am-11:46 pm

2 stops16h 16m

Santo Domingo Las Americas

Thu 3/5

6:00 am-9:20 pm

2 stops16h 20m

$456

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Tue 3/3

6:00 am-2:15 pm

1 stop7h 15m

Santo Domingo Las Americas

Thu 3/5

3:40 pm-11:40 pm

1 stop9h 00m

$520

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sat 1/10

6:30 am-11:46 pm

2 stops16h 16m

Santo Domingo Las Americas

Sat 1/17

6:00 am-9:15 pm

2 stops16h 15m

$526

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Tue 3/3

6:00 am-2:15 pm

1 stop7h 15m

Santo Domingo Las Americas

Thu 3/5

3:40 pm-11:40 pm

1 stop9h 00m

$538

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sat 11/1

6:00 am-1:41 pm

1 stop7h 41m

Santo Domingo Las Americas

Thu 11/6

3:56 pm-11:08 pm

1 stop8h 12m

$545

Flights are sorted by cheapest round-trip flights first.

Sorted by cheapest first

See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Harrisburg to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Harrisburg and Santo Domingo?

What is the cheapest day to depart on your flight to Santo Domingo?

Our data shows that Tuesday is the least expensive day to fly to Santo Domingo. Tickets to fly out on this day can be as low as $496. The most expensive day to fly to Santo Domingo is Saturday, with ticket prices averaging around $644.

When to book flights from Harrisburg to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Harrisburg to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Harrisburg to Santo Domingo (MDT to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to Santo Domingo

Direct flights

None
There are no direct flights from Harrisburg to Santo Domingo. There are no popular flight routes from Harrisburg to Santo Domingo.
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  • How far is Harrisburg to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 1560.2 mi away from Harrisburg. By plane, this route typically takes 7h 15m.

  • When did momondo last update prices for flights from Harrisburg Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Harrisburg Airport to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Harrisburg Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Harrisburg Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Harrisburg Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents required for your trip to Santo Domingo Las Americas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santo Domingo Las Americas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Harrisburg to Santo Domingo?

Best airlines flying from Harrisburg to Santo Domingo

Compare and see reviews for airlines that fly from Harrisburg to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
DeltaPriceFrom $420Free CancellationRating
7.9
7,969 reviews
Search Delta flights
American AirlinesPriceFrom $441Free CancellationRating
7.2
11,043 reviews
Search American Airlines flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to Santo Domingo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santo Domingo from Harrisburg.

Can I find flights from Harrisburg to Santo Domingo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santo Domingo from Harrisburg with this policy.

How can momondo help me find flights from Harrisburg to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from Harrisburg. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Harrisburg to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from Harrisburg are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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