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Cheap flights from Harrisburg to Santo Domingo from $260

This is the cheapest one-way flight price found by a momondo user in the last 72 hours by searching for a flight from Harrisburg to Santo Domingo departing on 6/10. Fares may change, and may not be available for all flights or travel dates. Click the price to refresh the search for this deal.
1 adult
0 bags

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Find the cheapest flights from Harrisburg to Santo Domingo

Cheap round-trip flights

Enter your travel dates to find the best prices.
American Airlines Logo
7:30 pm - 3:24 pm
MDT
-
SDQ
19h 54m
2 stops
American Airlines Logo
2:22 pm - 11:45 am
SDQ
-
MDT
21h 23m
2 stops
$381American Airlines
Tue, Aug 11 - Tue, Aug 18
American Airlines Logo
7:34 pm - 1:00 pm
MDT
-
SDQ
17h 26m
1 stop
American Airlines Logo
2:22 pm - 11:45 am
SDQ
-
MDT
21h 23m
2 stops
$386American Airlines
Tue, Aug 11 - Tue, Aug 18
Delta Logo
5:15 pm - 1:28 pm
MDT
-
SDQ
20h 13m
2 stops
Delta Logo
2:53 pm - 11:43 pm
SDQ
-
MDT
8h 50m
1 stop
$484Delta
Fri, Aug 14 - Wed, Aug 19
Delta Logo
5:15 pm - 1:28 pm
MDT
-
SDQ
20h 13m
2 stops
Delta Logo
2:53 pm - 11:36 am
SDQ
-
MDT
20h 43m
2 stops
$539Delta
Fri, Aug 14 - Fri, Aug 21
Delta Logo
5:15 pm - 1:28 pm
MDT
-
SDQ
20h 13m
2 stops
Delta Logo
2:53 pm - 11:36 am
SDQ
-
MDT
20h 43m
2 stops
$550Delta
Sun, Aug 9 - Wed, Aug 19
Delta Logo
5:15 pm - 1:28 pm
MDT
-
SDQ
20h 13m
2 stops
Delta Logo
2:53 pm - 11:43 pm
SDQ
-
MDT
8h 50m
1 stop
$564Delta
Fri, Aug 14 - Tue, Aug 18
Multiple Airlines Logo
7:13 pm - 10:53 am
MDT
-
SDQ
15h 40m
1 stop
Multiple Airlines Logo
3:30 pm - 5:02 pm
SDQ
-
MDT
25h 32m
2 stops
$566Multiple Airlines
Mon, Aug 10 - Sun, Aug 16
Delta Logo
12:17 pm - 1:28 pm
MDT
-
SDQ
25h 11m
2 stops
Delta Logo
2:53 pm - 11:43 pm
SDQ
-
MDT
8h 50m
1 stop
$570Delta
Thu, Aug 13 - Wed, Aug 19
Multiple Airlines Logo
10:26 am - 10:53 am
MDT
-
SDQ
24h 27m
1 stop
Multiple Airlines Logo
3:30 pm - 5:02 pm
SDQ
-
MDT
25h 32m
2 stops
$574Multiple Airlines
Sat, Aug 8 - Sun, Aug 16
American Airlines Logo
7:30 pm - 3:24 pm
MDT
-
SDQ
19h 54m
2 stops
American Airlines Logo
2:00 pm - 11:03 pm
SDQ
-
MDT
9h 03m
1 stop
$578American Airlines
Tue, Aug 18 - Mon, Sep 7

American Airlines flights from Harrisburg to Santo Domingo

Our best American Airlines deals on Harrisburg to Santo Domingo flight tickets
American Airlines
Aug 11
MDT7:30 pmHarrisburg
19h 54m
2 stops
SDQ3:24 pmSanto Domingo Las Americas
Aug 18
SDQ2:22 pmSanto Domingo Las Americas
21h 23m
2 stops
MDT11:45 amHarrisburg
$381
American Airlines
Aug 11
MDT7:34 pmHarrisburg
17h 26m
1 stop
SDQ1:00 pmSanto Domingo Las Americas
Aug 18
SDQ2:22 pmSanto Domingo Las Americas
21h 23m
2 stops
MDT11:45 amHarrisburg
$386
American Airlines
May 20
MDT7:51 pmHarrisburg
16h 54m
1 stop
SDQ12:45 pmSanto Domingo Las Americas
May 24
SDQ1:45 pmSanto Domingo Las Americas
20h 23m
1 stop
MDT10:08 amHarrisburg
$431

United Airlines flights from Harrisburg to Santo Domingo

Our best United Airlines deals on Harrisburg to Santo Domingo flight tickets
United Airlines
May 21
MDT7:59 pmHarrisburg
18h 11m
2 stops
SDQ2:10 pmSanto Domingo Las Americas
May 30
SDQ6:00 amSanto Domingo Las Americas
18h 27m
2 stops
MDT12:27 amHarrisburg
$767
United Airlines
May 21
MDT6:15 amHarrisburg
31h 55m
2 stops
SDQ2:10 pmSanto Domingo Las Americas
May 30
SDQ6:00 amSanto Domingo Las Americas
18h 27m
2 stops
MDT12:27 amHarrisburg
$788
United Airlines
May 21
MDT7:59 pmHarrisburg
18h 11m
2 stops
SDQ2:10 pmSanto Domingo Las Americas
May 30
SDQ6:00 amSanto Domingo Las Americas
13h 47m
2 stops
MDT7:47 pmHarrisburg
$789

momondo Fare Finder

 
Customize your flight search to find flights from Harrisburg to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, momondo users made 832,500 searches. Data last updated May 14, 2026.
Use the filters below to find and compare flights from Harrisburg to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Tue 8/11

7:30 pm-3:24 pm

2 stops19h 54m

Santo Domingo Las Americas

Tue 8/18

2:22 pm-11:45 am

2 stops21h 23m

$381

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Tue 8/11

7:34 pm-1:00 pm

1 stop17h 26m

Santo Domingo Las Americas

Tue 8/18

2:22 pm-11:45 am

2 stops21h 23m

$386

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Fri 8/14

5:15 pm-1:28 pm

2 stops20h 13m

Santo Domingo Las Americas

Wed 8/19

2:53 pm-11:43 pm

1 stop8h 50m

$484

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Fri 8/14

5:15 pm-1:28 pm

2 stops20h 13m

Santo Domingo Las Americas

Fri 8/21

2:53 pm-11:36 am

2 stops20h 43m

$539

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sun 8/9

5:15 pm-1:28 pm

2 stops20h 13m

Santo Domingo Las Americas

Wed 8/19

2:53 pm-11:36 am

2 stops20h 43m

$550

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Fri 8/14

5:15 pm-1:28 pm

2 stops20h 13m

Santo Domingo Las Americas

Tue 8/18

2:53 pm-11:43 pm

1 stop8h 50m

$564

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Mon 8/10

7:13 pm-10:53 am

1 stop15h 40m

Santo Domingo Las Americas

Sun 8/16

3:30 pm-5:02 pm

2 stops25h 32m

$566

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Thu 8/13

12:17 pm-1:28 pm

2 stops25h 11m

Santo Domingo Las Americas

Wed 8/19

2:53 pm-11:43 pm

1 stop8h 50m

$570

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Sat 8/8

10:26 am-10:53 am

1 stop24h 27m

Santo Domingo Las Americas

Sun 8/16

3:30 pm-5:02 pm

2 stops25h 32m

$574
Quickest round-trip

HarrisburgSanto Domingo

MDT - SDQ

MDTSDQ

Harrisburg

Tue 8/18

7:30 pm-3:24 pm

2 stops19h 54m

Santo Domingo Las Americas

Mon 9/7

2:00 pm-11:03 pm

1 stop9h 03m

$578

Flights are sorted by cheapest round-trip flights first.

Showing 1-10 of 20 resultsSorted by cheapest first
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See travel insights to Santo Domingo from

How to get the cheapest flight ticket from Harrisburg to Santo Domingo

Look no further. We've gone through all the searches for this route on momondo so you have the important information and insights to find the cheapest flight ticket for your trip

What is the typical price of a round-trip flight between Harrisburg and Santo Domingo?

What is the cheapest month to fly to Santo Domingo?

If you don’t want to visit Santo Domingo in September, then you should wait until October to fly from Harrisburg, when ticket prices are also cheap, with an average price of $465.

Can stopping save me money on Harrisburg to Santo Domingo flights?

You could potentially save up to 52% on your flight if you consider stops on a Harrisburg to Santo Domingo flight.

When to book flights from Harrisburg to Santo Domingo

Are you open to changing your travel dates? Check out the ideal times to fly from Harrisburg to Santo Domingo according to our flight data. Find out which month and days have the cheapest flights.
Estimated round-trip price

Cheap Harrisburg to Santo Domingo (MDT to SDQ) flight deals and tips

Find info about flight duration, direct flights, and airports for your flight from Harrisburg to Santo Domingo

Fastest flight time

7h 28m

Direct flights

None
The fastest flight from Harrisburg to Santo Domingo takes 7h 28m
There are no direct flights from Harrisburg to Santo Domingo. There are no popular flight routes from Harrisburg to Santo Domingo.
Search flight deals

Frequently asked questions about flying from Harrisburg to Santo Domingo

  • How far is Harrisburg to Santo Domingo Las Americas by plane?

    Santo Domingo Las Americas is 1560.2 mi away from Harrisburg. By plane, this route typically takes 7h 28m.

  • When did momondo last update prices for flights from Harrisburg Airport to Santo Domingo Las Americas Airport?

    Prices for flights from Harrisburg Airport to Santo Domingo Las Americas Airport are updated daily.

  • How many operators does momondo search for flights from Harrisburg Airport to Santo Domingo Las Americas Airport?

  • How old do you have to be to fly from Harrisburg Airport to Santo Domingo Las Americas Airport?

    The minimum age for a child to fly alone is five, but airlines that offer an unaccompanied minor (UNMR) service may have their own age limitations. Flight duration, scheduling, and layovers are among the considerations that may influence age limits. We recommend that you double-check with the airline you are booking with for travel from Harrisburg Airport to Santo Domingo Las Americas Airport.

  • What documentation or ID do you need to fly to Santo Domingo Las Americas Airport?

    The travel and health documents required for your trip to Santo Domingo Las Americas Airport can vary based on your itinerary and personal situation. As a rule, consider having multiple documents such as a national ID card or driver’s license, and a passport valid for six-months after you plan to arrive at Santo Domingo Las Americas Airport. We always recommend checking with your airline or a trusted third party such as IATA to get advice.

  • What is the most popular airline from Harrisburg to Santo Domingo?

Best airlines flying from Harrisburg to Santo Domingo

Compare and see reviews for airlines that fly from Harrisburg to Santo Domingo with momondo
Airline
Rating
Free Cancellation
Price
American AirlinesPriceFrom $399Free CancellationRating
7.1
11,664 reviews
Search American Airlines flights
DeltaPriceFrom $464Free CancellationRating
7.9
8,452 reviews
Search Delta flights

Traveling to a place near Santo Domingo?

Book flights to Santo Domingo if you plan to visit one of these locations
Juan Dolio

Why use momondo?

Why should I use momondo to find a flight deal from Harrisburg to Santo Domingo?

To find the flight that best suits your needs, momondo gathers a range of flights from a large pool of different airlines and agents; you can then use our insights and filters to find and book the right flight to Santo Domingo from Harrisburg.

Can I find flights from Harrisburg to Santo Domingo with flexible booking policies on momondo?

Yes. momondo enables you to select and highlight flights to Santo Domingo from Harrisburg with this policy.

How can momondo help me find flights from Harrisburg to Santo Domingo?

momondo provides multiple filters to help you find the best flight to Santo Domingo from Harrisburg. Filter by price, airline, airports, cabin, aircraft, payment method, number of stops and more.

I’m not ready to book a flight from Harrisburg to Santo Domingo right now. Can momondo alert me if prices change?

Price alerts on flights to Santo Domingo from Harrisburg are quick and easy to set up on momondo. Simply perform a search and select the price alert feature. It is as simple as that.

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